Markowitz, US
Aaron F. Markowitz, Huntsville, AL US
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20080294505 | METHODS AND SYSTEMS FOR TASK ASSESSMENT MANAGEMENT - Methods and systems for managing an assessment of tasks using a computer implemented task assessment management system are provided. The method includes generating a program objective by a customer that defines an end-product to be supplied to the customer by a contractor and generating a plurality of tasks that support supplying the end-product to the customer, the plurality of tasks including at least one metric that defines the performance of the task to support supplying the supplying the end-product to the customer. The method also includes evaluating the contractor performance in completing each of the plurality of tasks using the respective at least one metric, the self-assessment stored in a memory of the task assessment management system and evaluating the contractor performance in completing each of the plurality of tasks by the customer using the respective at least one metric and the self-assessment. | 11-27-2008 |
Baruch Markowitz, Monroe, NY US
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20140371038 | Exercise Apparatus and System for Stationary Users - Exercise equipment, particularly a linear movable structure and associated selectable elastic resistance bands with or without guide track members are designed to allow low-impact exercises for one or two persons at the same time while permitting either or both participants to remain stationary when utilizing the equipment. | 12-18-2014 |
Batsheva Markowitz, Brooklyn, NY US
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20090320173 | STRAP ATTACHMENT FOR ATTACHING ITEMS TO GARMENTS - A strap attachment for fastening an object to a baby garment may include an adornment for attaching to the baby garment; a strap extending from the adornment; a first fastener including two releasably engagable parts, a first engageable part fixedly attached to the strap, and a second engageable part fixedly attached to the strap between the first end and the first part of the two engageable parts; and a second fastener including two releasably engagable parts, a first engageable part of the second fastener fixedly attached to the garment at a location of the garment that is spatially separated from the adornment and from the first end of the strap, and a second engageable part of the second fastener attached to the strap at a location backing one of the first part of the first fastener and the second part of the first fastener. | 12-31-2009 |
David Markowitz, Plymouth Meeting, PA US
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20130218838 | MOVEABLE STORAGE - A mobile storage system is disclosed that in one aspect identifies a geographical location change of a user, such as movement from a first geographical location to a second geographical location. In response, the mobile storage system may move the user's information to a storage device associated with the second geographical location so that the user's information may be accessed by the user more efficiently. | 08-22-2013 |
20130308470 | Wireless Network Supporting Extended Coverage of Service - A communications access point may provide access to a wireless communications network to a user device located at a first location. The communications access point may determine that the user device is moving from the first location to a second location where access to the wireless network is limited or not available. In response to the determination, the communications access point may provide access to the wireless network at the second location by extending a coverage area of the wireless network. | 11-21-2013 |
20140297582 | Movable Storage - A mobile storage system is disclosed that in one aspect identifies a geographical location change of a user, such as movement from a first geographical location to a second geographical location. In response, the mobile storage system may move the user's information to a storage device associated with the second geographical location so that the user's information may be accessed by the user more efficiently. | 10-02-2014 |
David Markowitz, New York, NY US
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20090249234 | SYSTEM AND METHOD FOR EFFICIENTLY DISPLAYING SCORE INFORMATION RELATED TO ENTITIES - A system and method for graphically presenting profile data includes providing a plurality of fields on a display, each field representing a different trait. The fields are populated with a representative shape. Each shape represents a trait or sub trait where the shape represents a magnitude of the trait or sub trait. The traits and sub traits collectively provide an entity profile. Graphic modification to the representative shape permits a comparison with another entity profile with graphically depicted traits in accordance with the graphic modification. | 10-01-2009 |
Harold Toby Markowitz, Roseville, MN US
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20110106196 | IDENTIFICATION AND TREATMENT OF JUNCTIONAL RHYTHMS - An implantable medical device and associated method provide atrial pacing and measure intervals between atrial pacing pulses and subsequently sensed ventricular events. A decreasing trend in the of intervals indicative of a pre-junctional rhythm is detected. The atrial pacing pulse is delivered at a shortened atrial pacing pulse interval in response to detecting the decreasing trend to reduce the likelihood of a junctional rhythm. | 05-05-2011 |
Jared Markowitz, Columbia, MD US
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20160082331 | Force-sensing net - In exemplary implementations of this invention, a basketball net or flat net measures the translational kinetic energy of a ball that passes through an aperture in the net or impacts the net. The net includes one or more electrically conductive cords, which have a resistance that varies depending on the degree to which the cord is stretched. From sensor measurements, a processor determines: (a) instantaneous rate of change of resistance, and (b) duration of a time period that begins when resistance exceeds a baseline (with hysteresis). In the case of a basketball net, a processor may calculate the translational kinetic energy of the ball as equal to a sum of two terms. The first term is inversely proportional to the square of the duration; the second is proportional to the square of the integral of the instantaneous rate of change of resistance over the time period. | 03-24-2016 |
Jared Markowitz, Cambridge, MA US
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20130172131 | Force-sensing net - In exemplary implementations of this invention, a basketball net or flat net measures the translational kinetic energy of a ball that passes through an aperture in the net or impacts the net. The net includes one or more electrically conductive cords, which have a resistance that varies depending on the degree to which the cord is stretched. From sensor measurements, a processor determines: (a) instantaneous rate of change of resistance, and (b) duration of a time period that begins when resistance exceeds a baseline (with hysteresis). In the case of a basketball net, a processor may calculate the translational kinetic energy of the ball as equal to a sum of two terms. The first term is inversely proportional to the square of the duration; the second is proportional to the square of the integral of the instantaneous rate of change of resistance over the time period. | 07-04-2013 |
20130310979 | Neuromuscular Model-Based Sensing And Control Paradigm For A Robotic Leg - A neuromuscular model-based controller for a robotic limb having at least one joint includes a neuromuscular model having a muscle model, muscle geometry and reflex feedback loop to determine at least one torque or impedance command to be sent to the robotic limb. One or more parameters that determine relation between feedback data and activation of the muscle model are adjusted consequent to sensory data from at least one of an intrinsic sensor and an extrinsic sensor. A controller in communication with the neuromuscular model is configured to receive the at least one torque or impedance command and controls at least one of position, torque and impedance of the robotic limb joint. | 11-21-2013 |
John S. Markowitz, Gainesville, FL US
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20120245201 | Isopropylphenidate for Treatment of Attention-Deficit/Hyperactivity Disorder and Fatigue-Related Disorders and Conditions - The present invention relates to the identification of isopropylphenidate as a useful therapeutic agent in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) as well as various fatigue causing disease and disorders and medication induced fatigue. | 09-27-2012 |
20140162896 | COMPOSITIONS AND METHODS FOR GENOTYPING CES1 GENETIC VARIANTS AND USE THEREOF - The invention features compositions and methods that are useful for genotyping CES1 isoforms (CES1A1, CES1A2, CES1A3). The ability to specifically genotype one or more CES1 isoforms (e.g. CES1A1) is useful for assessing drug metabolism in a subject and guiding treatment selection. | 06-12-2014 |
John S. Markowitz, Charleston, SC US
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20110020801 | Carboxylesterase-1 Polymorphisms and Methods of Use Therefor - Methods and kits are provided for detecting polymorphisms in carboxylesterase-1 (CES1). Several single nucleotide polymorphisms (SNPs) in CES1 in humans, and methods for detecting the same, are provided (e.g., Gly143Glu, 12754T>del). Results indicate that the Gly143Glu (9486G>A) polymorphism has an allelic frequency of 1.5% in the Caucasian population. Polymorphisms of the present invention may alter the function of the carboxylesterase-1 enzyme (hCES1). Thus, the methods and kits of the present invention may be used to personalize a therapy and/or avoid adverse consequences of altered metabolism of a therapeutic or compound (e.g., enalapril, methylphenidate, etc.) which may result due to a CES1 polymorphism. In addition, recombinant cells lines overexpressing wild-type CES1 or expressing CES1 mutants are provided. Such cell lines may be used to assess the effects of candidate compounds on CES1, and the action of CES1 on these candidate compounds. | 01-27-2011 |
Jonathan Markowitz, Chicago, IL US
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20160078466 | MANAGING LOYALTY REWARDS - A loyalty rewards management system includes a server, which includes a database including current values of loyalty points customers have available for redemption with vendors from whom the customers have earned loyalty points, wherein each of the current values of loyalty points corresponds to a particular customer and a particular vendor. The server also includes an interaction tracker that is configured to record an interaction between the customer and the vendor. The system also includes a vendor device and a customer device. The customer device includes a location determining system that is involved in a determination of whether the customer device is in proximity to the vendor device. The interaction tracker is configured to receive interaction information from the customer device and/or the vendor device and update the current value of loyalty points corresponding to the customer and the vendor based thereon. | 03-17-2016 |
Kenneth Markowitz, Fanwood, NJ US
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20120329790 | Dentinal Drug Delivery Composition - The present invention is a dentinal drug delivery composition composed of cationic and/or neutral porous particles containing an effective amount of a therapeutic agent and a method for using the same to provide a dental treatment. | 12-27-2012 |
20130065866 | DENTINAL DRUG DELIVERY COMPOSITION AND SCREENING METHOD - The present invention is a dentinal drug delivery composition composed of cationic and/or neutral porous particles containing an effective amount of a therapeutic agent, a method for using the dentinal drug delivery to provide a dental treatment, and a method for identifying anti-inflammatory agents capable of diffusing through dentin. | 03-14-2013 |
Leo Markowitz, Brooklyn, NY US
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20120270663 | Inflatable Vehicles for Simulating Driving for use with Handheld Video Games - An inflatable vehicle for simulating a driving experience while playing realistic computer-video driving games such as the WII games and handheld game players. The vehicle is life-like in construction and allows a player to sit therein while playing driving game. A steering wheel or handle bar is configured to receive a game controller or a motion-sensitive handheld game player. Movement of the steering wheel, thus, correspondingly controls images on a video game screen. | 10-25-2012 |
Lipa Markowitz, Brooklyn, NY US
Patent application number | Description | Published |
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20100304873 | Bowling Ball and Football Game Controller - A ball-shaped housing for encapsulating a game controller. The game controller is held in a compartment within the hollow of a ball. A user accesses control buttons on the game controller by way of buttons on the housing that are mechanically linked to contact ends that are in close proximity to the game controller buttons. When a user presses the buttons on the housing, its mechanical linkages transfer motion to the contact ends, which press respective buttons on the game controller. The invention allows a player to approximate real game conditions and allows for a realistic gaming experience | 12-02-2010 |
20110272880 | INFLATABLE VEHICLES FOR SIMULATING DRIVING FOR USE WITH VIDEO GAMES - An inflatable vehicle for simulating a driving experience while playing realistic computer-video driving games such as the WII games, The vehicle is life-like in construction and allows a player to sit therein while playing driving game. A steering wheel or handle bar is configured to receive a game controller—which controls the video game when the steering wheel or handle bar is manipulated like a real life equivalent thereof. | 11-10-2011 |
20120040728 | Inflatable Vehicles for Simulating Driving for use with Video Games - An inflatable vehicle for simulating a driving experience while playing realistic computer-video driving games such as the WII games. The vehicle is life-like in construction and allows a player to sit therein while playing driving game. A steering wheel or handle bar is configured to receive a game controller—which controls the video game when the steering wheel or handle bar is manipulated like a real life equivalent thereof. | 02-16-2012 |
Lynn Markowitz, Waltham, MA US
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20150252108 | GLYCOPROTEIN PREPARATIONS - Preparations of glycoproteins, e.g., therapeutic preparations of glycoproteins, having altered levels of affinity for Fcγ receptors relative to reference glycoprotein preparations, and methods of making and methods of using such preparations, are described. | 09-10-2015 |
20150299331 | MODIFIED GLYCOPROTEINS - Modified glycoproteins, and methods of making and using such modified glycoproteins, are described. | 10-22-2015 |
Martin Markowitz, New York, NY US
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20130177583 | MOLECULAR CLONE OF HIV-1 - The present invention relates, in general, to HIV-1 and, in particular, to a molecular clone of HIV-1. The invention further relates to methods of inducing an immune response to HIV-1 in a patient and to immunogens suitable for use in such methods. The invention also relates to anti-HIV-1 antibodies and to methods of using same to prevent or treat HIV-infection. | 07-11-2013 |
Michael A. Markowitz, Burke, VA US
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20090325261 | Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles - Enzymes are modified by incorporating anchor sites for linking the enzymes to a target surface without destroying the catalytic activity of the enzymes. A stable carrier to accommodate and bind the selected enzyme is constructed, and the enzyme is non-covalently liked to the carrier, generally through metal salts of iminodiacetate | 12-31-2009 |
Michael A. Markowitz, Springfield, VA US
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20090130422 | MESOPOROUS MONOLITHS CONTAINING CONDUCTING POLYMERS - The present invention relates to a mesoporous monolith containing a conducting polymer such as poly(3,4-ethylenedioxythiophene) and methods for making the monolith. The mesoporous monolith is electroactive, at least semi-transparent and has one or more of a large internal pore surface area, pore size and pore volume. It can be used for various applications in photovoltaics, sensing electrochromics, separations, reversible ion exchange and control of protein activity. The method employs hydrothermal treatment and/or substantially complete drying to obtain the desirable properties of the monolith. Conducting polymer can be covalently bound to the internal pore surfaces and polymerized in situ to partially or completely fill the pores producing increased mechanical strength and a high conductivity per unit area. | 05-21-2009 |
20100073847 | TETHER-CONTAINING CONDUCTING POLYMERS - A compound having the formula below. X is hydroxyl, a sulfonic ester or salt thereof, a phosphonate or salt thereof, a carboxylate or salt thereof, or a boronic ester or salt thereof. The value n is an integer greater than or equal to 2. A polymer made by polymerizing the compound. A method of: reacting NH | 03-25-2010 |
20100081205 | FLUOROPHORE EMBEDDED/INCORPORATING/BRIDGED PERIODIC MESOPOROUS ORGANOSILICAS AS RECOGNITION ELEMENTS FOR OPTICAL SENSORS - Periodic mesoporous organosilicas (PMO) which incorporate an optically active molecule into the material for use as an optical indicator of target binding. This material combines the stability, selectivity, and high density of binding sites characteristic of the PMO with the sensitivity and selectivity of the optically active molecule. The material undergoes a change when exposed to a sample containing a target molecule. The change can be observed by visual inspection or through the use of fluorescence spectra. | 04-01-2010 |
20100083736 | HYBRID PRECONCENTRATOR FOR DETECTION OF MATERIALS - A device having: one or more substrates in an enclosure having an inlet and an outlet; a template directed molecular imprinted material on the substrates; and a heater to heat the material. A method of: providing the above device including a sensor coupled to the outlet; flowing a gas though the device; heating the material; and flowing any vapor evolved from the material into the sensor. | 04-08-2010 |
20110223331 | Mesoporous Monoliths Containing Conducting Polymers - The present invention relates to a mesoporous monolith containing a conducting polymer such as poly(3,4-ethylenedioxythiophene) and methods for making the monolith. The mesoporous monolith is electroactive, at least semi-transparent and has one or more of a large internal pore surface area, pore size and pore volume. It can be used for various applications in photovoltaics, sensing electrochromics, separations, reversible ion exchange and control of protein activity. The method employs hydrothermal treatment and/or substantially complete drying to obtain the desirable properties of the monolith. Conducting polymer can be covalently bound to the internal pore surfaces and polymerized in situ to partially or completely fill the pores producing increased mechanical strength and a high conductivity per unit area. | 09-15-2011 |
20110305894 | COMPOSITE FOR CONTROLLED RELEASE OF SMALL MOLECULES IN AQUATIC ENVIRONMENTS - A composite material formulated for slow release of a small molecule in seawater includes a porous inorganic oxide framework and micelles embedded within the pores of the framework. The micelles include a surfactant and a small molecule, the surfactant being present in the composite material at no more than 80 parts by weight per 100 parts by weight inorganic oxide, the composite material being stable in seawater for releasing the small molecule over at least 20 days. | 12-15-2011 |
20130011459 | Composite for Controleed Release of Small Molecules in Aquatic Environments - A composite material formulated for slow release of a small molecule in seawater includes a porous inorganic oxide framework and micelles embedded within the pores of the framework. The micelles include a surfactant and a small molecule, the surfactant being present in the composite material at no more than 80 parts by weight per 100 parts by weight inorganic oxide, the composite material being stable in seawater for releasing the small molecule over at least 20 days. | 01-10-2013 |
Michael Ira Markowitz, Brooklyn, NY US
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20100057629 | Inventive Process Documentation, Management, and Stimulation System - A system for use in an inventive process for at least one invention includes at least one of a conception module that is adapted to receive, process and communicate information associated with conception and reduction to practice of the at least one invention; an exploitation module that is adapted to receive, process and communicate information associated with deciding whether to exploit the at least one invention in a market place; a testing module that is adapted to receive, process and communicate information associated with testing of the at least one invention; and a patent application module that is adapted to receive, process and communicate information associated with preparation, filing and prosecution of the at least one invention. Each of the modules is adapted for installation and operation with one or more computer devices, and further adapted to share particular information associated with the inventive process with at least another one of the modules. | 03-04-2010 |
Robert E. Markowitz, Glen Rock, NJ US
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20130041703 | SYSTEM AND METHOD FOR MANAGING IMMIGRATION STATUS - Disclosed herein are systems, methods, and non-transitory computer-readable storage media for managing immigration status. A system configured to practice the method identifies a project, such as a work contract. The system identifies a worker assigned to the project, wherein an immigration status of the worker requires the worker to have a visa, such as an H-1B visa, to participate in the project. The system electronically prepares and tracks immigration documentation associated with the visa in order to allow the worker to participate in the project. Then the system determines if an event occurs that impacts the immigration status, and, if the event occurs, the system updates the immigration documentation based on the event. The immigration documentation can include a labor condition application (LCA) and/or a public access file (PAF). The system can prepare the immigration documentation based on information stored in a personal profile of the worker. | 02-14-2013 |
20140059183 | Proxy Apparatus and Method for Streaming Media Information and for Increasing the Quality of Stored Media Information - A proxy apparatus and method for streaming media information via at least one network and for building-up a good quality version of the media information are provided. When a user device communicates with the proxy apparatus using a particular bandwidth and requests that media information be provided, the proxy apparatus first determines if a version of the media information encoded for the user device's connection bandwidth has been stored in the proxy apparatus. If a version of the media information encoded for the user device's bandwidth is not available from the proxy apparatus, the proxy apparatus sends a request to a media server for the media information. If the version of the media information has missing packets, the proxy device sends retransmission requests to the media server to obtain the missing packets, thereby building-up a good quality version of the media information. | 02-27-2014 |
Robert Edward Markowitz, Glen Rock, NJ US
Patent application number | Description | Published |
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20100242072 | NETWORK-BASED SERVICE TO PROVIDE ON-DEMAND VIDEO SUMMARIES OF TELEVISION PROGRAMS - A network-based device allows customers to receive television programming and to view summaries of the programming. A method of providing the summaries comprises: dividing a received program into program segments each identified by index marks, summarizing each program segment into summary segments identified by similar index marks, generating metadata files for delimiting a beginning and an end of summary segments and program segments, storing the summary segments and accessing the summary segments to supply the summary segments in lieu of program segments upon demand. | 09-23-2010 |
20110035641 | Proxy Apparatus and Method for Streaming Media Information and for Increasing the Quality of Stored Media Information - A proxy apparatus and method for streaming media information via at least one network and for building-up a good quality version of the media information. When a user device communicates with the proxy apparatus using a particular bandwidth and requests that media information be provided, the proxy apparatus first determines if a version of the media information encoded for the user device's connection bandwidth has been stored in the proxy apparatus. If a version of the media information encoded for the user device's bandwidth is not available from the proxy apparatus, the proxy apparatus sends a request to a media server for the media information. If the version of the media information has missing packets, the proxy device sends retransmission requests to the media server to obtain the missing packets, thereby building-up a good quality version of the media information. | 02-10-2011 |
20120072959 | NETWORK-BASED SERVICE TO PROVIDE ON-DEMAND VIDEO SUMMARIES OF TELEVISION PROGRAMS - A network-based device allows customers to receive television programming and to view summaries of the programming. A method of providing the summaries comprises: dividing a received program into program segments each identified by index marks, summarizing each program segment into summary segments identified by similar index marks, generating metadata files for delimiting a beginning and an end of summary segments and program segments, storing the summary segments and accessing the summary segments to supply the summary segments in lieu of program segments upon demand. | 03-22-2012 |
20130042283 | Method and Apparatus for Automatically Converting Source Video into Electronic Mail Messages - The invention relates to a method and system for automatically identifying video content within source video and transmitting the video content to an electronic mail client. The transmitted video content can be streaming video, video files, and/or other medium derived from the source video. An enhanced electronic mail client is also disclosed. | 02-14-2013 |
20140053218 | NETWORK-BASED SERVICE TO PROVIDE ON-DEMAND VIDEO SUMMARIES OF TELEVISION PROGRAMS - A network-based device allows customers to receive television programming and to view summaries of the programming. A method of providing the summaries comprises: dividing a received program into program segments each identified by index marks, summarizing each program segment into summary segments identified by similar index marks, generating metadata files for delimiting a beginning and an end of summary segments and program segments, storing the summary segments and accessing the summary segments to supply the summary segments in lieu of program segments upon demand. | 02-20-2014 |
20160100209 | Method and Apparatus for Automatically Converting Source Video into Electronic Mail Messages - The invention relates to a method and system for automatically identifying video content within source video and transmitting the video content to an electronic mail client. The transmitted video content can be streaming video, video files, and/or other medium derived from the source video. An enhanced electronic mail client is also disclosed. | 04-07-2016 |
Sanford Markowitz, Pepper Pike, OH US
Patent application number | Description | Published |
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20120164638 | Digital Quantification of DNA Methylation - Abnormal DNA methylation can be used as a biomarker in cancer patients. For such purposes, it is important to determine precisely the fraction of methylated molecules in an analyzed sample. A technology we term Methyl-BEAMing achieves this goal. Individual bisulfite-treated DNA molecules can be PCR-amplified within aqueous nanocompartments containing beads, resulting in a population of beads each containing thousands of copies of the template molecule. After hybridization with probes specific for methylated sequences, the beads can be analyzed by flow cytometry. This approach enables detection and enumeration of one methylated molecule in a population of ˜5000 unmethylated molecules. Methyl-BEAMing provides digital quantification of rare methylation events and is generally applicable to the assessment of methylated genes in clinical samples. | 06-28-2012 |
20150072998 | COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY - Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein. | 03-12-2015 |
Sanford D. Markowitz, Pepper Pike, OH US
Patent application number | Description | Published |
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20090061453 | Methods and compositions for detecting colon cancers - This application describes methods and compositions for detecting and treating HLTF-associated neoplasia. Differential methylation of the HLTF nucleotide sequences has been observed in HLTF-associated neoplasia such as colon neoplasia. | 03-05-2009 |
20090311726 | Methods and compositions for categorizing patients - The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular markers, and methods for identifying candidate molecular markers in highly parallel gene expression data. | 12-17-2009 |
20100009359 | Methods and compositions for detecting colon cancers - This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia. | 01-14-2010 |
20100209906 | Methods and compositions for detecting colon cancers - This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia. | 08-19-2010 |
20100284989 | 15-PGDH IN COLON CANCER - The disclosure provides, among other things, a method of decreasing resistance to the chemopreventive properties of non-steroidal anti-inflammatory agents, e.g., celecoxib, particularly in the prevention of cancer, e.g., colon cancer, by increasing the levels or activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). The disclosure also provides a method of identifying compounds that upregulate or reactivate 15-PGDH. The disclosure also provides a method of identifying an individual suitable for treatment with a non-steroidal anti-inflammatory agent in the treatment or prevention of colon cancer. | 11-11-2010 |
20110027283 | METHODS FOR DIAGNOSING AND TREATING CANCERS - This disclosure provides methods and compositions for inhibiting immune responses. The disclosure also provides methods and compositions for inhibiting graft rejection and promoting or prolonging graft survival. | 02-03-2011 |
20110165567 | ABERRANT METHYLATION OF C6Orf150 DNA SEQUENCES IN HUMAN COLORECTAL CANCER - This application describes methods and compositions for detecting and treating C6Orf150-associated neoplasia. Differential methylation of the C6Orf150 nucleotide sequences has been observed in C6Orf150-associated neoplasia such as colon neoplasia. | 07-07-2011 |
20110217708 | METHODS AND COMPOSITIONS FOR DETECTING COLON CANCERS - This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia. | 09-08-2011 |
20120094287 | METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS - This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder. | 04-19-2012 |
20120329077 | METHODS AND COMPOSITIONS FOR CATEGORIZING PATIENTS - The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular markers, and methods for identifying candidate molecular markers in highly parallel gene expression data. | 12-27-2012 |
20130131329 | METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS - This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder. | 05-23-2013 |
20130280241 | 15-PGDH IN COLON CANCER - The disclosure provides, among other things, a method of decreasing resistance to the chemopreventive properties of non-steroidal anti-inflammatory agents, e.g., celecoxib, particularly in the prevention of cancer, e.g., colon cancer, by increasing the levels or activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). The disclosure also provides a method of identifying compounds that upregulate or reactivate 15-PGDH. The disclosure also provides a method of identifying an individual suitable for treatment with a non-steroidal anti-inflammatory agent in the treatment or prevention of colon cancer. | 10-24-2013 |
20140113290 | ABERRANT METHYLATION OF C6ORF150 DNA SEQUENCES IN HUMAN COLORECTAL CANCER - This application describes methods and compositions for detecting and treating C6Orf150-associated neoplasia. Differential methylation of the C6Orf150 nucleotide sequences has been observed in C6Orf150-associated neoplasia such as colon neoplasia. | 04-24-2014 |
20140206855 | METHODS AND COMPOSITIONS FOR DETECTING CANCERS ASSOCIATED WITH METHYLATION OF HMLH1 PROMOTER DNA - Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay. | 07-24-2014 |
20140220679 | METHODS AND COMPOSITIONS FOR CATEGORIZING PATIENTS - The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular markers, and methods for identifying candidate molecular markers in highly parallel gene expression data. | 08-07-2014 |
20140221505 | METHODS AND COMPOSITIONS FOR CATEGORIZING PATIENTS - The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular markers, and methods for identifying candidate molecular markers in highly parallel gene expression data. | 08-07-2014 |
Steve Markowitz, Honolulu, HI US
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20120245994 | TRACKING AND REWARDING MAILER RESPONSE - Direct mail campaigns for a plurality of vendors are included in a rewards program. The corresponding mailers have a distinctive identifier visible from the outside of the mailer and a unique code inside the mailer that is not visible from the outside of the mailer. Recipients of the mailers submit the corresponding unique codes to a rewards program implementer that tracks recipients' responses to the mailers and rewards the recipients for promoted activities. | 09-27-2012 |
Steven Markowitz, Ventura, CA US
Patent application number | Description | Published |
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20110131113 | SCHEDULED REPETITIVE SEARCH - A host computing device conducts scheduled repetitive searches for a resource to be purchased and delivery according to a specified delivery schedule. A customer provides the host with a description of the resource and provides a specified delivery schedule. The host computing device conducts automated scheduled repetitive searches for the resource, selects a vendor offering the resource based on a criterion (e.g., lowest price), and conducts the respective purchases such that the resources are delivered in accordance with the specified delivery schedule. Here, the resource may be purchased from a first vendor in a first purchase and a second, different vendor in a subsequent second purchase for the resource. | 06-02-2011 |
20120215657 | Vendor Selection for Purchase of Resources - A vendor sends, to a host, affiliate links for resources that the vendor is offering for sale and formatting for its on-line order form. The host uses the affiliate links and a vendor selection criterion to select a vendor from which to purchase a customer's desired resource. The host populates, without further customer input, the order form of the selected vendor. The host receives a purchase availability status for the desired resource and, when the desired resource is available, completes the purchase from the selected vendor, without any additional customer input. When the desired resource is unavailable, the host populates an order form of another selected vendor using the respective formatting and completes the purchase without any additional customer input. | 08-23-2012 |
Steven M. Markowitz, Honolulu, HI US
Patent application number | Description | Published |
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20080317795 | HIGHLY CHARGED MICROCAPSULES - The invention encompasses compositions containing sol-gel microcapsules that are highly positively charged. The sol-gel capsules generally contain additives. The invention also encompasses methods for producing highly charged microcapsules using cationic additives which can include cationic polymers. The methods allow for the encapsulation of polar or non-polar active ingredients. | 12-25-2008 |
20120203715 | Bodywash Additive Business Methods - The invention encompasses business methods that include supplying an additive for addition to a bodywash, or a bodywash containing such an additive, and receiving payment for the additive or bodywash, as well as encompassing business methods that include designing, testing, and marketing an additive for addition to a bodywash. | 08-09-2012 |
20120207804 | SUNSCREEN COMPOSITIONS AND METHODS OF USE - The invention encompasses additives for addition to a bodywash, where the additives contain one or more sunscreens, and where a bodywash which contains the additive imparts to the skin an SPF of at least about 2, in some cases at least about 5, or 10, or 15. Also described are methods of making and using the additives. | 08-16-2012 |
20150347582 | Method of Redirecting Search Queries from an Untrusted Search Engine to a Trusted Search Engine - A method of redirecting search queries from an untrusted search engine to a trusted search engine is a software application that is used to prevent personal information from being collected by untrusted search engines. The software application receives a search query URL for a desired search engine which corresponds to a search query. The search query is compared to a provided plurality of untrusted URL patterns in order to determine if the desired search engine can be trusted. If the search query URL is not found on in the plurality of untrusted URL patterns, the search is allowed to proceed. If the search query URL is found in the plurality of untrusted URL patterns, the search query is redirected to a trusted search engine. At least one trusted URL pattern is provided so that the search can be redirected to a trusted search engine. | 12-03-2015 |
Toby H. Markowitz, Roseville, MN US
Patent application number | Description | Published |
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20150080762 | Devices and Systems for Navigation and Positioning a Central Venous Catheter Within a Patient - Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet. | 03-19-2015 |