Patent application number | Description | Published |
20090182130 | Methods of protein production using ovomucoid promoters - Methods of producing protein using a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences. | 07-16-2009 |
20090188002 | Artificial chromosomes and transchromosomic avians - The invention includes avians containing an artificial chromosome in their genome and methods of making the avians. | 07-23-2009 |
20090193534 | In vivo transfection in avians - The present invention provides for methods of producing transgenic avians which may include delivering a heterologous nucleic acid to oviduct tissue of an avian wherein the nucleic acid enters a cell of the oviduct tissue and is expressed. | 07-30-2009 |
20090210951 | Avian transgenesis using an ovalbumin nucleotide sequence - The invention includes delivering to an avian a nucleic acid molecule which includes nucleotide sequence of an ovalbumin gene expression controlling region and a heterologous coding sequence operably linked to the gene expression controlling region wherein the heterologous coding sequence is expressed in a cell of the avian. | 08-20-2009 |
20090299037 | METHODS OF PURIFYING PROTEINS FROM EGG WHITE - The invention provides methods of purifying proteins, e.g., cytokines, from egg whites. | 12-03-2009 |
20100083389 | Production of heterologous protein in the avian oviduct - The invention includes methods of making transgenic avians by introducing a nucleic acid sequence into the genome of an avian embryo wherein the nucleic acid sequence comprises a nucleotide sequence encoding a heterologous protein, developing the avian embryo to hatch, developing the hatched chick to sexual maturity and obtaining offspring from the sexually mature hatched chick which produce egg white containing the heterologous protein. | 04-01-2010 |
20100310552 | Antibodies produced in the avian oviduct - The invention relates to transgenic avians which produce antibodies in the egg white by introducing a nucleic acid sequence into the genome of an avian embryo wherein the nucleic acid sequence comprises a nucleotide sequence encoding an antibody and to the antibodies and to methods related thereto. | 12-09-2010 |
20130095092 | RECOMBINANT HUMAN NAGLU PROTEIN AND USES THEREOF - The present invention provides compositions comprising an isolated mixture of recombinant human NaGlu proteins in which a substantial amount of the NaGlu proteins in the mixture has increased levels of phosphorylated mannose that confer the proteins to be efficiently internalized into human cells. The present invention also provides methods of producing such mixture of NaGlu proteins, vectors used in transgenesis and expression, host cells harboring such vectors, and methods of isolating and purifying the mixture of NaGlu proteins. The invention further provides methods of treating NaGlu associated diseases. | 04-18-2013 |
20140255383 | RECOMBINANT HUMAN NAGLU PROTEIN AND USES THEREOF - The present invention provides compositions comprising an isolated mixture of recombinant human NaGlu proteins in which a substantial amount of the NaGlu proteins in the mixture has increased levels of phosphorylated mannose that confer the proteins to be efficiently internalized into human cells. The present invention also provides methods of producing such mixture of NaGlu proteins, vectors used in transgenesis and expression, host cells harboring such vectors, and methods of isolating and purifying the mixture of NaGlu proteins. The invention further provides methods of treating NaGlu associated diseases. | 09-11-2014 |