Marinier
Anne Marinier, Kirland CA
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20100022503 | AMINOPYRAZOLE KINASE INHIBITORS - The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents. | 01-28-2010 |
Anne Marinier, Kirkland CA
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20100041636 | NOVEL KINASE INHIBITORS - The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts thereof. The Formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1 and IGFR-1, thereby making them useful as anti-cancer agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors. | 02-18-2010 |
20100048581 | THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS - The invention provides compounds of formula I [INSERT CHEMICAL STRUCTURE HERE] (I) and pharmaceutically acceptable salts thereof. The formula I thiazolyl compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease. | 02-25-2010 |
20100120770 | THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS - The invention provides compounds of formula I | 05-13-2010 |
20130165426 | IMIDAZOPYRIDINE, IMIDAZOPYRIMIDINE AND IMIDAZOPYRAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS - Disclosed is a compound of Formula I or a salt thereof, in which X, X1, X2, R1, R2, and R3 are described herein. Also disclosed are pharmaceutical compositions and methods of using the compounds of Formula I to treat disorders mediated by melanocortin-4 receptors. | 06-27-2013 |
20140057894 | PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS - Disclosed herein is a compound of Formula I: wherein X, R | 02-27-2014 |
20140235499 | ASSAY FOR INHIBITORS OF CIP/KIP PROTEIN DEGRADATION - An assay and system compatible with high throughput screening (HTS) that is capable of identifying inhibitors, such as small-molecule inhibitors, of the degradation of the Cdk inhibitor p21, are described. The assay is based on the use of fusion protein comprising (i) a p2 polypeptide; and (i) a reporter protein linked to the C-terminal of said p21 polypeptide, wherein the fusion protein has a half-life that is similar to that of the p21 polypeptide. Inhibitors identified by this assay may be useful to inhibit the proliferation of tumor cells, and thus for the treatment of cancers. | 08-21-2014 |
20150119390 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRIDAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION - The present invention provides imidazothiadiazole compounds of Formula (I); Wherein W, Y, R | 04-30-2015 |
20150197520 | PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS - Disclosed herein is a compound of Formula I: | 07-16-2015 |
Laurent Marinier, Lumbin FR
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20130054154 | SYSTEM AND METHOD FOR ASSESSING INHOMOGENEOUS DEFORMATIONS IN MULTILAYER PLATES - A method and device for evaluating inhomogeneous deformations in a first wafer bonded by molecular adhesion to a second wafer. This evaluation method includes the steps of making at least one reading of a plurality of measurement points, the reading corresponding to a surface profile of the first wafer along a predefined direction and over a predefined length, computing a second derivative from the measurement points of the surface profile and evaluating a level of inhomogeneous deformations in the first wafer according to the second derivative. | 02-28-2013 |
Paul Marinier US
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20110249578 | CHANNEL STATE INFORMATION TRANSMISSION FOR MULTIPLE CARRIERS - Channel state information is reported in periodic and aperiodic reports for multiple component carriers or serving cells. Channel state information may be reported for a subset of aggregated downlink carriers or serving cells. For an aperiodic report, the carrier(s)/serving cell(s) for which channel state information is reported are determined based on the request for the aperiodic report. When a CQI/PMI/RI report and a HARQ ACK/NACK report coincide in a subframe, the HARQ ACK/NACK report is transmitted on PUCCH, and the CQI/PMI/RI report is transmitted on PUSCH. | 10-13-2011 |
Paul Marinier, Bressard CA
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20130215837 | Method And Apparatus For Supporting Uplink Protocol Changes - A method and apparatus for supporting uplink (UL) protocol changes includes reconfiguring a medium access control (MAC) protocol. A hybrid automatic repeat request (HARM) process is flushed, and a MAC-e/es reset is performed. | 08-22-2013 |
20150289131 | METHOD AND APPARATUS FOR SUPPORTING UPLINK PROTOCOL CHANGES - A method and apparatus for supporting uplink (UL) protocol changes includes reconfiguring a medium access control (MAC) protocol. A hybrid automatic repeat request (HARM) process is flushed, and a MAC-e/es reset is performed. | 10-08-2015 |
Paul Marinier, Brossard, CA US
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20160037532 | METHOD AND APPARATUS FOR MAPPING OF ABSOLUTE POWER GRANT VALUES IN WIRELESS COMMUNICATIONS - A method and apparatus for adjusting power grants in wireless communications. Multiple power grant tables are stored and one or more tables are designated during communication. | 02-04-2016 |
Paul Marinier, Quebec CA
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20110110238 | METHOD AND APPARATUS FOR PREVENTING TRANSMISSION BLOCKING IN AN HSUPA WIRELESS COMMUNICATION SYSTEM - A method and apparatus for preventing mitigating transmission blocking are provided. A wireless transmit/receive unit (WTRU) detects whether transmission of a medium access control (MAC) flow, such as a MAC dedicated transport channel flow, is prevented by a small non-zero grant. Transmission blocking may be detected when a non-zero grant is smaller than required for transmission of a MAC protocol data unit. If transmission blocking is detected, the WTRU transmits scheduling information. The WTRU may continue to periodically transmit scheduling information on a condition that the blocking continues. | 05-12-2011 |
Paul Marinier, Montreal CA
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20110205945 | METHOD AND APPARATUS FOR TRANSMITTING AND RECEIVING A PACKET VIA HIGH SPEED DOWNLINK PACKET ACCESS - A method and apparatus for transmitting and receiving a packet via high speed downlink packet access (HSDPA) are disclosed. At least one HSDPA medium access control (MAC-hs) service data unit (SDU) is segmented into a plurality of segments. MAC-hs protocol data units (PDUs) are generated from the segments wherein each MAC-hs PDU includes at least one segment. Each MAC-hs PDU may include one segment from a single MAC-hs SDU. The size of the segments may match to the size of the MAC-hs PDUs minus the size of the header of the MAC-hs PDU. The sizes of the segments may be determined based on the number of segments to which the MAC-hs SDU is segmented. Alternatively, each MAC-hs PDU may include a combination of segments from a plurality of MAC-hs SDUs or a combination of at least one segment from one MAC-hs SDU and at least one entire MAC-hs SDU. | 08-25-2011 |
20120250521 | CONTROLLING INTER-CELL INTERFERENCE IN FORWARD ACCESS CHANNEL (CELL_FACH) STATE - Since common E-DCH resources may be assigned from a single Node B, uplink macro-diversity may not be possible between neighboring Node B's. In addition, a user equipment (UE) assigned a common E-DCH resource may not be allowed to perform cell reselection. Thus, maintaining the assignment of a common E-DCH resource to a given UE for more than a few hundred milliseconds may result in unacceptable inter-cell interference, for example, when the UE moves closer to a neighboring cell controlled by a non-serving Node B. To overcome inter-cell interference and allow a more extensive utilization of the Cell_FACH state, a method may be used to detect and/or control inter-cell interference. | 10-04-2012 |