Maria Begona
Maria Begona Cachon-Gonzalez, Saffron Walden GB
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20130090374 | METHODS FOR THE TREATMENT OF TAY-SACHS DISEASE, SANDHOFF DISEASE, AND GM1-GANGLIOSIDOSIS - The present disclosure provides methods for the treatment of lysosomal storage disorders using gene replacement therapy. In particular, methods are provided for the treatment of Tay-Sachs disease, Sandhoff Disease, and GM1-gangliosidosis using enzyme replacement therapy. Expression constructs encoding enzymes required for ganglioside metabolism are delivered to the brain of subjects with an enzyme deficiency. Methods are also provided for delaying the onset of, reducing the likelihood of onset of, or reducing the severity of Tay-Sachs disease, Sandhoff Disease, and GM1-gangliosidosis. | 04-11-2013 |
Maria Begona Castro Feo, Leioa ES
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20110256186 | BIOMATERIAL BASED ON WHARTON'S JELLY FROM THE HUMAN UMBILICAL CORD - The present invention relates to a biomaterial, specifically a hydrogel, formed from the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans isolated exclusively from the Wharton's jelly of the umbilical cord which can optionally contain cells, and also to the methods for the production and use thereof. | 10-20-2011 |
20130095049 | ANTIOXIDANT COMPOSITION - The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds. | 04-18-2013 |
Maria Begona Delgado-Charro, Copponex FR
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20090281405 | METHOD FOR NON-INVASIVELY DETERMINING THE RELATIVE LEVELS OF TWO BIOLOGICAL SUBSTANCES - An iontophoretic sampling device for non-invasively determining the relative levels of two substances present in a biological system. | 11-12-2009 |
Maria Begona Ruiz-Arguello, Berango ES
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20090104178 | Chemokine binding activity of viral tnf receptors and related proteins - Chemokine binding activity of viral TNF receptors and related proteins. The invention relates to a C-terminal domain (CTD) of viral tumour necrosis factor receptors (vTNFRs) CrmB or CrmD or CTD homologues (CTD1, CTD2 and CTD3) from poxvirus and their functional homologues, including derivatives, and fragments, for use in binding chemokines and their analogues and/or to enhance the immunomodulatory properties of TNFRs or in bloking binding of chemokines to their corresponding cell surface receptors and/or to modulate chemokine biological activity. | 04-23-2009 |
Maria Begona Seijo Rey, Santiago De Compostela ES
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20110142890 | NANOPARTICLES OF CHITOSAN AND HYALURONAN FOR THE ADMINISTRATION OF ACTIVE MOLECULES - The present invention relates to a nanoparticulate system useful for the delivery of pharmacologically active molecules, and especially for transfecting polynucleotides into cells. It comprises nanoparticles of chitosan of low molecular weight and hyaluronan. | 06-16-2011 |
Maria Begona Villada-Moiron, Almere NL
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20160132482 | AUTOMATIC ONTOLOGY GENERATION FOR NATURAL-LANGUAGE PROCESSING APPLICATIONS - A method of generating ontologies for a Virtual Assistant across different languages may include extracting a plurality of tokens in a first language from a plurality of web resources in a web domain that includes the Virtual Assistant. The web resources may be made available in a first language and a second language. The method may also include determining a first part-of-speech (POS) for each of the plurality of tokens, where the first POS may be specific to the first language. The method may additionally include mapping the first POS to a second POS from a standardized set of POS's that are general across the first language and the second language, and generating a plurality of lemmas from the plurality of tokens. The method may further include displaying a network representing the ontology. | 05-12-2016 |
20160132484 | AUTOMATIC GENERATION OF N-GRAMS AND CONCEPT RELATIONS FROM LINGUISTIC INPUT DATA - A method of automatically generating a lemma dictionary from a web resource may include extracting a plurality of tokens from text-based documents within the web resource, and generating a plurality of N-grams from the plurality of tokens. The method may additionally include receiving one or more filter definitions that identify valid N-grams, and filtering the plurality of N-grams using the one or more filter definitions to generate a lemma dictionary. The method may further include generating an ontology that comprises the lemma dictionary. | 05-12-2016 |
Maria Begoña Aguilera Diez, Leiden NL
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20140045763 | COMPOUNDS FOR TREATING, DELAYING AND/OR PREVENTING A HUMAN GENETIC DISORDER SUCH AS MYOTONIC DYSTROPHY TYPE I (DMI) - The current invention provides new compounds for treating, delaying and/or preventing a human genetic disorder such as myotonic dystrophy type 1 (DM1), spino-cerebellar ataxia 8 and/or Huntington's disease-like 2 caused by expansions of CUG repeats in the transcripts of DM1/DMPK, SCA8 or JPH3 genes. | 02-13-2014 |
Maria Begoña Castrofeo, Leioa ES
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20110158963 | THREE-DIMENSIONAL MATRICES OF STRUCTURED POROUS MONETITE FOR TISSUE ENGINEERING AND BONE REGENERATION, AND METHOD OF THE PREPARATION THEREOF - The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc. | 06-30-2011 |
Maria Begoña Castro Feo, Derio ES
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20120135445 | CELL TRANSPORT SYSTEM - The present invention relates to a system for cell transport Said system allows the transport of cells, assuring their integrity and viability during the entire transport process. It consists of a system suitable for a wide variety of formats which allows a broad range of technical applications of the system The system of the invention allows providing ready-to-use cells, without the cells having to be manipulated before they are used by technical experts in cell biology The invention particularly relates to an agarose plus agarase mixture covering or enveloping, depending on the format of the selected transport system, the cell culture, protecting it during the transport process, as well as to the methodology of cell recovery of the cells transported in the system. | 05-31-2012 |
Maria Begoña Castro Feo, Leioa ES
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20130095049 | ANTIOXIDANT COMPOSITION - The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a skin disease or condition resulting from reactive oxygen species production in the skin or involving reactive oxygen species production in the skin, to a hydrogel containing said combination as well as to dressing wounds comprising said hydrogel and its use in the healing of ulcers, wounds, burns and scalds. | 04-18-2013 |
Maria Begoña Castro Feo, Leioa (bizkaia) ES
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20130095143 | BIOMATERIAL FROM WHARTON'S JELLY UMBILICAL CORD - The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton's jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof. | 04-18-2013 |
Maria Begoña Castro Feo, Leioa (bizkaia) ES
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20130095143 | BIOMATERIAL FROM WHARTON'S JELLY UMBILICAL CORD - The present invention relates to a biomaterial, specifically a hydrogel, based on the extracellular matrix of the umbilical cord for its application in regenerative medicine. The invention particularly relates to a biomaterial made up of glycosaminoglycans present exclusively in the Wharton's jelly of the umbilical cord (which can optionally be combined with cells as a combination therapy), and also to the methods for the production and use thereof. | 04-18-2013 |
Maria Begoña Coco Martin, Valladolid ES
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20110164215 | DEVICE FOR ASSISTING AND PROTECTING VISION - The invention relates to a device comprising one left electrochromic filter ( | 07-07-2011 |
Maria Begoña Hernandez Olasagarre, Barcelona ES
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20150291595 | PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS - New pyrrolotriazinone derivatives having the chemical structure of Formula (I) are disclosed; as well as process for theft preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). | 10-15-2015 |
Maria Begoña Jordá Albiñana, Valencia ES
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20110054253 | METHOD AND DEVICE FOR AUTOMATED TRANSLATIONAL MOVEMENT OF AN ENDOSCOPE THROUGH THE DIGESTIVE TRACT - Device for automated translational movement of an endoscope through the digestive tract, comprising, at least: (i) pneumatic translational movement means; and (ii) electronic control means, that enable the automated and coordinated method of the translational movement means. The translational movement means include: at least one radial chamber immobilized on the endoscope; at least one bellows-shaped axial chamber connected via one end to the body of the endoscope; at least one radial chamber floating on the endoscope and secured to the second end of the bellows-shaped axial chamber. | 03-03-2011 |
Maria Begoña Jordá Albiñana, Valencia ES
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20110054253 | METHOD AND DEVICE FOR AUTOMATED TRANSLATIONAL MOVEMENT OF AN ENDOSCOPE THROUGH THE DIGESTIVE TRACT - Device for automated translational movement of an endoscope through the digestive tract, comprising, at least: (i) pneumatic translational movement means; and (ii) electronic control means, that enable the automated and coordinated method of the translational movement means. The translational movement means include: at least one radial chamber immobilized on the endoscope; at least one bellows-shaped axial chamber connected via one end to the body of the endoscope; at least one radial chamber floating on the endoscope and secured to the second end of the bellows-shaped axial chamber. | 03-03-2011 |