Mankin, US
Alexander Mankin, River Forest, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090042186 | MAPPING NEW SITES FOR ANTIBIOTIC ACTION IN THE RIBOSOME - The present invention provides a method of mapping and identifying new sites for antibiotic action in the ribosome of a microorganism. The method comprises: (a) providing a random mutant library of the rRNA genes of the microorganism prepared by randomly mutating the rRNA genes of the microorganism; (b) enriching the library in clones with deleterious rRNA mutants by negative selection; (c) screening for clones with deleterious rRNA mutations; (d) mapping the deleterious rRNA mutations in the clones obtained from step (c) to identify sites in the rRNA which are important functional sites in the ribosome; and (e) selecting functional sites identified in the rRNA in step (d) which are not targeted by a known antibiotic as new sites for antibiotic action for the microorganism. The rRNA gene can be the 16S rRNA of the small subunit or the 23S rRNA or the 5S rRNA of the large subunit of the ribosome of the microorganism. | 02-12-2009 |
Alexander S. Mankin, River Forest, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110143998 | IDENTIFICATION AND USE OF PEPTIDE INHIBITORS OF PROTEIN SYNTHESIS - The present invention discloses compositions of peptide inhibitors of protein synthesis, and methods of identifying peptide inhibitors that are capable of inhibiting protein synthesis through an interaction at a stem-loop H18 in 16S rRNA of a 30S ribosomal subunit. Screening methods for peptides are disclosed, in addition to methods of determining the affinity of a test compound for a ribosomal subunit. | 06-16-2011 |
| 20120316106 | SYNERGISTIC ANTIBIOTIC COMBINATIONS AND DERIVATIVES - Improved antibiotic analogs, and synergistic combinations of antibiotics designed based on structural crystallographic analysis, are provided as well as pharmaceutical compositions that include these improved analogs and synergistic combinations, along with methods for their production and use. The synergistic combinations target neighboring sites in the ribosome demonstrating the importance of the corresponding ribosomal sites for development of clinically-relevant synergistic antibiotics. | 12-13-2012 |
| 20130267457 | PEPTIDE INHIBITORS OF PROTEIN SYNTHESIS - The present invention discloses compositions of peptide inhibitors of protein synthesis, and methods of identifying peptide inhibitors that are capable of inhibiting protein synthesis through an interaction at a stem-loop H18 in 16S rRNA of a 30S ribosomal subunit. Screening methods for peptides are disclosed, in addition to methods of determining the affinity of a test compound for a ribosomal subunit. | 10-10-2013 |
Allison Mankin, Bethesda, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20150106931 | CLASSIFYING MALWARE BY ORDER OF NETWORK BEHAVIOR ARTIFACTS - The present invention generally relates to systems and methods for classifying executable files as likely malware or likely benign. The techniques utilize temporally-ordered network behavioral artifacts together with machine learning techniques to perform the classification. Because they rely on network behavioral artifacts, the disclosed techniques may be applied to executable files with obfuscated code. | 04-16-2015 |
| 20150156162 | SMART NAVIGATION FOR SHORTENED URLS - The present invention generally relates to a system for, and method of, obtaining, from a first identifier in a first name space, a second identifier in a second name space. The disclosed technique involves obtaining the first identifier in the first name space from a source, applying a rule to the first identifier in the first name space, such that a second identifier in a second name space is obtained, and providing the second identifier, such that the source obtains the second identifier without resolving the first identifier using a domain name system (DNS). | 06-04-2015 |
| 20150256424 | NAME COLLISION RISK MANAGER - Embodiments relate to systems, devices, and computer-implemented methods for managing domain name space collisions by accessing information, such as a domain name string, corresponding to a domain name resolution request and response. Based on at least the domain name string, a type of use value associated with the request can be determined. Based on at least the type of use value, a name collision risk value for the request can be determined. If the name collision risk value indicates there is a specified risk of a domain name string collision, then a domain name collision mitigation strategy can be generated and/or implemented. | 09-10-2015 |
Glenn Mankin, Martinez, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100065238 | SILICA-BASED SOLS AND THEIR PRODUCTION AND USE - A process for producing an aqueous silica-based sol is disclosed wherein a cationic ion exchange resin having part of its ion exchange capacity in hydrogen form is contacted with an aqueous alkali metal silicate to form a slurry having a pH from 5.0 to 11.5 and/or having particle aggregation or microgel formation corresponding to a S value up to 45%; adjusting the pH using a material comprising an aluminium compound; and separating the resin from the slurry. | 03-18-2010 |
| 20100236738 | SILICA-BASED SOLS AND THEIR PRODUCTION AND USE - The invention relates to a process for producing aqueous silica-based sols which comprises providing a cationic ion exchange resin having at least part of its ion exchange capacity in hydrogen form; bringing said ion exchange resin in contact with an aqueous alkali metal silicate to form an aqueous slurry; adjusting the pH of the aqueous slurry and separating the ion exchange resin from the aqueous slurry, as well as the silica-based sols obtained by the process. | 09-23-2010 |
| 20110065812 | SILICA-BASED SOLS AND THEIR PRODUCTION AND USE - A process for producing an aqueous silica-based sol is disclosed wherein a cationic ion exchange resin having part of its ion exchange capacity in hydrogen form is contacted with an aqueous alkali metal silicate to form a slurry having a pH from 5.0 to 11.5 and/or having particle aggregation or microgel formation corresponding to a S value up to 45%; adjusting the pH using a material comprising an aluminum compound; and separating the resin from the slurry. | 03-17-2011 |
Jennifer Mankin, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20160094564 | TAXONOMIC MALWARE DETECTION AND MITIGATION - In an example, a classification engine compares two binary objects to determine whether they can be classified as belonging to a common family. As an example application, the classification engine may be used to detect malware objects derived from a common ancestor. To classify the object, the binary is disassembled and the resulting assembly code is normalized. Known “clean” functions, such as compiler-generated library code, are filtered out. Normalized blocks of assembly code may then be characterized, such as by forming N-grams, and checksumming each N-gram. These may be compared to known malware routines. | 03-31-2016 |
| 20160094570 | CROSS-VIEW MALWARE DETECTION - In an example, a cross-view detection engine is disclosed for detecting malware behavior. Malware may attempt to avoid detection by remaining in volatile memory for as long as possible, and writing to disk only when necessary. To avoid detection, the malware may also provide a pseudo-driver at a file system level that performs legitimate-looking dummy operations. A firmware-level driver may simultaneously perform malicious operations. The cross-view detection engine detects this behavior by deconstructing call traces from the file system-level operations, and reconstructing call traces from firmware-level operations. If the traces do not match, the object may be flagged as suspicious. | 03-31-2016 |
Kyle D. Mankin, Prospect, KY US
| Patent application number | Description | Published |
|---|---|---|
| 20110004037 | Use of Mixed Activity Dehydrogenation Catalyst Following Oxidative Reheat - Methods are disclosed for the dehydrogenation of feed streams, such as in the manufacture of styrene from ethylbenzene, using a catalyst bed having catalyst with differing activities. In particular, the use of upstream and downstream catalyst beds of relatively low and high activities, respectively, can reduce the production of unwanted byproducts, especially in styrene production processes employing an oxidative reheat step (oxidation zone) prior to ethylbenzene dehydrogenation. The methods allow the maximum temperature in the oxidation zone to be decreased, thereby reducing the formation of unwanted oxygenated byproducts (e.g., phenol). | 01-06-2011 |
Lacy Gallaway Mankin, Abilene, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20160114185 | Internal UV Treatment Administered Via Endoscopy - A device and method is proposed to enable the treatment of interior of bodily hollow organs and other interior cavities of a body for a number of harmful virus, fungal, and bacterial entities and autoimmune conditions by internal short wavelength ultraviolet light by use of specially equipped endoscope-like devices. | 04-28-2016 |
Luke Mankin, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090038025 | Selection system for maize transformation - The present invention relates to improved methods for the incorporation of DNA into the genome of a | 02-05-2009 |
| 20090083883 | D-Amino Acid Selection For Soybean - The present invention relates to improved methods and means for transformation of soybean ( | 03-26-2009 |
| 20090106856 | Selection System for Wheat - The present invention relates to improved methods for the incorporation of DNA into the genome of a wheat plant based on a D-alanine or D-serine selection. Preferably, the transformation is mediated by | 04-23-2009 |
| 20090249514 | Improved Methods for the Production of Stably Transformed, Fertile Zea Mays Plants - The present invention relates to improved methods for the incorporation of DNA into the genome of a | 10-01-2009 |
| 20090300800 | D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation - The present invention relates to improved methods for the incorporation of DNA into the genome of a barley plant based on a D-alanine or D-serine selection. Preferably, the transformation is mediated by | 12-03-2009 |
Maria G. Mankin, Pt. Reyes Station, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20130057030 | Collapsible Chair - A collapsible chair includes a frame having two sidepieces, each having a base portion and a back portion. The base has an upward facing concave edge complementary to a portion of a spherical profile of a seating ball, the base portion further includes a frontal aspect. Each sidepiece has one or more hinges to connect the two sidepieces. The sidepieces, when hinged together, are moveable between a collapsed arrangement and an open arrangement. The chair further includes a cross member having an upward facing concave edge complementary to a portion of the spherical profile of the seating ball. The cross member is configured to mate with the frontal aspects of the two sidepieces so as to stabilize the two sidepieces in the open position. The upward facing concave edges of the sidepieces and the cross member form a triangular cradle that supports the seating ball. | 03-07-2013 |
Maria G. Mankin, Point Reyes Station, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20140210248 | COLLAPSIBLE CHAIR - A collapsible chair includes a frame having two sidepieces, each having a base portion and a back portion. The base has an upward facing concave edge complementary to a portion of a spherical profile of a seating ball, the base portion further includes a frontal aspect. Each sidepiece has one or more hinges to connect the two sidepieces. The sidepieces, when hinged together, are moveable between a collapsed arrangement and an open arrangement. The chair further includes a cross member having an upward facing concave edge complementary to a portion of the spherical profile of the seating ball. The cross member is configured to mate with the frontal aspects of the two sidepieces so as to stabilize the two sidepieces in the open position. The upward facing concave edges of the sidepieces and the cross member form a triangular cradle that supports the seating ball. | 07-31-2014 |
Max N. Mankin, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20160141382 | Fabrication of Nanoscale Vacuum Grid and Electrode Structure With High Aspect Ratio Dielectric Spacers Between the Grid and Electrode - Some embodiments of vacuum electronics call for a grid that is fabricated in close proximity to an electrode, where, for example, the grid and electrode are separated by nanometers or microns. Methods and apparatus for fabricating a nanoscale vacuum grid and electrode structure are described herein. | 05-19-2016 |
Max N. Mankin, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20150213992 | ELECTRONIC DEVICE MULTI-LAYER GRAPHENE GRID - A vacuum electronic device includes a multi-layer graphene grid that includes at least two layers of graphene, where the transmission of electrons through the multi-layer graphene grid can be tuned by varying the parameters of the vacuum electronic device such as the number of graphene layers, relative positions of the electrodes, voltage biases applied to the electrodes, and other device parameters. | 07-30-2015 |
| 20150243468 | APPLICATIONS OF GRAPHENE GRIDS IN VACUUM ELECTRONICS - Graphene grids are configured for applications in vacuum electronic devices. A multilayer graphene grid is configured as a filter for electrons in a specific energy range, in a field emission device or other vacuum electronic device. A graphene grid can be deformable responsive to an input to vary electric fields proximate to the grid. A mesh can be configured to support a graphene grid. | 08-27-2015 |
| 20160120733 | GARMENT SYSTEM INCLUDING AT LEAST ONE SENSOR AND AT LEAST ONE ACTUATOR RESPONSIVE TO THE SENSOR AND RELATED METHODS - Embodiments disclosed herein relate to a garment system including at least one sensor, and at least one actuator that operates responsive to sensing feedback from the at least one sensor to selectively constrict or selectively dilate at least one flexible compression garment. Such selective constriction or dilation of the at least one flexible compression garment against at least one body part can improve muscle functioning or joint functioning during an activity, such as a sport or other activity. | 05-05-2016 |
| 20160120734 | GARMENT SYSTEM INCLUDING AT LEAST ONE SENSOR AND AT LEAST ONE ACTUATOR RESPONSIVE TO THE SENSOR AND RELATED METHODS - Embodiments disclosed herein relate to a garment system including at least one sensor, and at least one actuator that operates responsive to sensing feedback from the at least one sensor to activate a flexible compression garment to selectively constrict or selectively dilate. Such selective constriction or dilation against the at least one body part can improve muscle functioning, or joint functioning during an activity such as a sport or other athletic activity. | 05-05-2016 |
Robb Mankin, Loveland, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110060886 | Systems and Methods for Selecting Bit Per Cell Density of a Memory Cell Based on Data Typing - Various embodiments of the present invention provide systems and methods for selecting data encoding. As an example, some embodiments of the present invention provide methods that include receiving a data set to be written to a plurality of multi-bit memory cells that are each operable to hold at least two bits. In addition, the methods include determining a characteristic of the data set, and encoding the data set. The level of encoding is selected based at least in part on the characteristic of the data set. In some instances of the aforementioned embodiments, the characteristic of the data set indicates an expected frequency of access of the data set from the plurality of multi-bit memory cells. | 03-10-2011 |
| 20110185111 | Systems and Methods for Extended Life Multi-Bit Memory Cells - Various embodiments of the present invention provide for extended life operation of multi-bit memory cells. As an example, some embodiments of the present invention provide electronic systems that include a plurality of multi-bit memory cells, an encoding circuit and a decoding circuit. Each of the plurality of multi-bit memory cells is operable to hold at least two bits. The encoding circuit is operable to receive a data input including at least two data bits, and to encode the two data bits as an encoded output to the plurality of multi-bit memory cells. The encoded output may be selected to be either a single two bit output representing the two bits, or a series of two two bit outputs representing the two bits. The decoding circuit is operable to reverse the encoding applied by the encoding circuit. | 07-28-2011 |
Scots Mankin, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120284812 | Herbicide-Tolerant Plants - The present invention provides herbicide-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an herbicide to which herbicide-tolerant plants of the invention are tolerant. Plants of the invention may express an acetyl-Coenzyme A carboxylase enzyme that is tolerant to the action of acetyl-Coenzyme A carboxylase enzyme inhibitors. | 11-08-2012 |
| 20140045686 | HERBICIDE-TOLERANT PLANTS - The present invention provides herbicide tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an herbicide to which herbicide-tolerant plants of the invention are tolerant. Plants of the invention may express an acetyl-Coenzyme A carboxylase enzyme that is tolerant to the action of acetyl-Coenzyme A carboxylase enzyme inhibitors. | 02-13-2014 |
| 20160108423 | HERBICIDE-TOLERANT PLANTS - The present invention provides herbicide-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an herbicide to which herbicide-tolerant plants of the invention are tolerant. Plants of the invention may express an acetyl-Coenzyme A carboxylase enzyme that is tolerant to the action of acetyl-Coenzyme A carboxylase enzyme inhibitors | 04-21-2016 |
Scots L. Mankin, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120284853 | HERBICIDE-TOLERANT PLANTS - The present invention provides herbicide-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying an herbicide to which herbicide-tolerant plants of the invention are tolerant. Plants of the invention may express an acetyl-Coenzyme A carboxylase enzyme that is tolerant to the action of acetyl-Coenzyme A carboxylase enzyme inhibitors. | 11-08-2012 |
| 20130042366 | HERBICIDE-TOLERANT PLANTS - The present invention provides saflufenacil-tolerant plants. The present invention also provides methods for controlling the growth of weeds by applying saflufenacil to which the saflufenacil-tolerant plants of the invention are tolerant. Plants of the invention express a cytochrome P450 polypeptide, the expression of which confers, to the plants, tolerance to the saflufenacil. | 02-14-2013 |
| 20130111618 | HERBICIDE-TOLERANT PLANTS | 05-02-2013 |
Shevek Mankin, Dulles, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20150058139 | EXISTENT DOMAIN NAME DNS TRAFFIC CAPTURE AND ANALYSIS - Systems and methods for scoring a domain web traffic based on DNS traffic requests received at an authoritative name server to resolve the domain name. A request to resolve the domain name is received at an authoritative name server. A counter, such as a server counter or a hit counter, for the domain name is incremented based on the received request. A score, such as a domain traffic score or a domain rank, is calculated based upon a count of the counter. Calculating the score may also include applying a weighting factor to the counters based on information about a requesting set of resolvers and other domains/websites that may be linking and driving traffic to the domain whose traffic score is being calculated. Examples of relevant set of resolvers information may include location, traffic levels, traffic type and architecture of the set of resolvers. | 02-26-2015 |
Shevek Mankin, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110087769 | Domain Popularity Scoring - Systems and methods for scoring a domain including analyzing counter data and information obtained from a web site associated with the domain. Methods may include receiving requests to resolve the domain at an authoritative domain resolution server. A counter may be incremented for the domain based on the received requests. Information may be obtained from a web page associated with the domain. For example, obtaining information from the web page may include obtaining quantitative, qualitative, and/or functional information from the web page, such as link information, a status of network links corresponding to the link information, and associated ratios. The status of link information may include searching for functional details and/or results, such as, domain redirections, domain errors, mirror content, and commonly linked sites. A score may be calculated for the domain based upon the counter data and the information obtained from the web page associated with the domain. | 04-14-2011 |
| 20150089056 | DOMAIN POPULARITY SCORING - Systems and methods for scoring a domain including analyzing counter data and information obtained from a web site associated with the domain. Methods may include receiving requests to resolve the domain at an authoritative domain resolution server. A counter may be incremented for the domain based on the received requests. Information may be obtained from a web page associated with the domain. For example, obtaining information from the web page may include obtaining quantitative, qualitative, and/or functional information from the web page, such as link information, a status of network links corresponding to the link information, and associated ratios. The status of link information may include searching for functional details and/or results, such as, domain redirections, domain errors, mirror content, and commonly linked sites. A score may be calculated for the domain based upon the counter data and the information obtained from the web page associated with the domain. | 03-26-2015 |
S. Luke Mankin, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20140377835 | METHODS AND COMPOSITIONS FOR ISOLATING, IDENTIFYING AND CHARACTERIZING MONOCOT PLASTIDIC ACCASE HERBICIDE TOLERANT MUTATIONS USING A MODEL SYSTEM - The present invention relates compositions and methods for identifying, isolating, and characterizing herbicide tolerant mutations in monocot plastidic acetyl-CoA carboxylases using a model system. | 12-25-2014 |
| 20150252379 | Plants Having Increased Tolerance to Herbicides - The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants. | 09-10-2015 |
Terri Mankin, Warsaw, OH US
Yona Benjamin Mankin, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20140298091 | Fault Tolerance for a Distributed Computing System - In one embodiment, a method detects a failure of a container in a controller node where the container includes a service being performed and isolated from other services being performed in other containers on the controller node. The controller node terminates the container including the service and determines a known state for the service. The known state is known to be operational without including a cause of the failure and the service operated from the known state saving changes to the known state during operation separately from the known state. The controller node restarts the service in a new container that replaces the terminated container where the restarted service starts from the known state without using the changes. | 10-02-2014 |
| 20140304695 | Update Management for a Distributed Computing System - In one embodiment, a method receives a software upgrade package for a management computer and main computer. The management computer upgrades software of the management computer using the software upgrade package where the upgrading replaces an image of the software of the management computer with an image from the software upgrade package. Upon upgrade of the management computer, the management computer initiates an upgrade of the main computer. The main computer withdraws use of the services, and upon the withdrawing, the management computer reboots the main computer. Then, the main computer upgrades software of the main computer using the software upgrade package upon rebooting where the upgrading replaces an image of the software of the main computer with an image from the software upgrade package. Upon the upgrading, the main computer restores the use of the services. | 10-09-2014 |