Patent application number | Description | Published |
20090246869 | Differentiation of Primate Pluripotent Stem Cells to Hematopoietic Lineage Cells - The invention provides methods of differentiating primate pluripotent stem cells into cells of hematopoietic lineage. The invention further provides hematopoietic lineage cells differentiated from primate pluripotent stem cells, as well as methods of using the same and kits comprising the same. | 10-01-2009 |
20100086999 | DIFFERENTIATION OF PRIMATE PLURIPOTENT CELLS TO HEPATOCYTE-LINEAGE CELLS - Methods for differentiating primate pluripotent stem cells into hepatocyte-lineage cells are provided. In certain embodiments, the methods utilize sequential culturing of the primate pluripotent stem cells in certain growth factors to produce hepatocyte-lineage cells. In certain embodiments, the population of cells produced by the methods is further enriched for hepatocyte-lineage cells. | 04-08-2010 |
20100240130 | Differentiation and Enrichment of Islet-like Cells from Human Pluripotent Stem Cells - Methods for differentiating human pluripotent stem cells into islet-like cells are provided. In certain embodiments, the methods utilize sequential culturing of the human pluripotent stem cells with certain factors to produce islet-like cells. In certain embodiments, the population of cells produced by the methods is further enriched for islet-like cells. | 09-23-2010 |
20120107931 | DIFFERENTIATION OF PRIMATE PLURIPOTENT STEM CELLS TO HEMATOPOIETIC LINEAGE CELLS - The invention provides methods of differentiating primate pluripotent stem cells into cells of hematopoeitic lineage. The invention further provides hematopoietic lineage cells differentiated from primate pluripotent stem cells, as well as methods of using the same and kits comprising the same. | 05-03-2012 |
20130337561 | Differentiation and Enrichment of Islet-Like Cells from Human Pluripotent Stem Cells - Methods for differentiating human pluripotent stem cells into islet-like cells are provided. In certain embodiments, the methods utilize sequential culturing of the human pluripotent stem cells with certain factors to produce islet-like cells. In certain embodiments, the population of cells produced by the methods is further enriched for islet-like cells. | 12-19-2013 |
Patent application number | Description | Published |
20100332492 | RETRIEVAL OF RELEVANT OBJECTS IN A SIMILARITY - Techniques for retrieval of one or more relevant multi-attribute structured objects with respect to a query are provided. The techniques include receiving a query, grouping one or more attributes of one or more objects in a database into one or more groups according to how each bears a relation to the query, and using the one or more attribute groups to produce an output of one or more relevant multi-attribute structured objects in response to the query. | 12-30-2010 |
20110106580 | SYSTEM AND METHOD FOR EXAMPLE BASED TARGETED MARKETING - Embodiments of the invention provide retailers with the ability to employ concept-based marketing using only a few representative examples. Embodiments of the invention take seed examples, utilize the seed examples to provide an expanded list (that can be edited as desired) representative of the concept, and map the expanded list to a final set of customers to be included in a targeted marketing operation. | 05-05-2011 |
20110106711 | DECISION SUPPORT SYSTEM AND METHOD FOR DISTRIBUTED DECISION MAKING FOR OPTIMAL HUMAN RESOURCE DEPLOYMENT - A decision support tool which takes a high-level view of supply and demand in the realm of labor resources and produces globally-optimal recommendations for assignment of practitioners to open seats. These assignments preferably optimize a utility function composed of different business metrics and can be customizable for different organizations and priorities. | 05-05-2011 |
20110235909 | ANALYZING DOCUMENTS USING STORED TEMPLATES - A method, a system and a computer program product for analyzing a document are disclosed. In response to receiving the document, the document is partitioned into a plurality of segments using a set of pre-defined attributes. The plurality of segments of the document is mapped with corresponding segments of at least one template selected from a set of stored templates. A first template from the set of stored templates is selected and a group of segments in the first template is identified by computing at least one of a structural similarity and a textual similarity associated with the group of segments compared with the plurality of segments of the document. A subset of segments from the group of segments is aligned with corresponding segments from the plurality of segments of the document. A set of scores is computed using a set of pre-defined criteria, in response to the mapping. The document is analyzed based on the computed set of scores. | 09-29-2011 |
20120278350 | METHODS AND ARRANGEMENTS FOR PROVIDING EFFECTIVE INTERACTIVE QUERY SUGGESTIONS WITHOUT QUERY LOGS - Methods and arrangements for providing interactive query suggestions. A partial user query phrase is received, the partial query phrase comprising a final word element. A vocabulary is accessed and, from the vocabulary, at least one possible completion of the final word element is ascertained. A phrase index is accessed and, from the phrase index, at least two phrases corresponding to completions of the partial user query phrase with the at least one possible completion of the final word element are ascertained. A probability score is assigned to each of the at least two phrases, and the at least two phrases are ranked based on probability. | 11-01-2012 |
20120323952 | PROVIDING EFFECTIVE INTERACTIVE QUERY SUGGESTIONS WITHOUT QUERY LOGS - Methods and arrangements for providing interactive query suggestions. A partial user query phrase is received, the partial query phrase comprising a final word element. A vocabulary is accessed and, from the vocabulary, at least one possible completion of the final word element is ascertained. A phrase index is accessed and, from the phrase index, at least two phrases corresponding to completions of the partial user query phrase with the at least one possible completion of the final word element are ascertained. A probability score is assigned to each of the at least two phrases, and the at least two phrases are ranked based on probability. | 12-20-2012 |
20130103682 | COMPUTER-IMPLEMENTED INFORMATION REUSE - Embodiments of the present invention relate to an approach for reusing information/knowledge. Specifically, embodiments of the present invention provide an approach for retrieving previously stored data to satisfy queries (e.g., jobs/tickets) for solutions to problems while maintaining privacy/security of the data as well as ensuring the quality of the results. In a typical embodiment, a query for a solution to a problem is received and details are extracted therefrom. Using the details, a search is performed on a set of data stored in at least one computer storage device. Based on the search, a set of results will be generated and classified into a set of categories. In any event, the quality of each of the set of results will be assessed based on the usefulness of the set of results. | 04-25-2013 |
20140207772 | COMPUTER-IMPLEMENTED INFORMATION REUSE - Embodiments of the present invention relate to an approach for reusing information/knowledge. Specifically, embodiments of the present invention provide an approach for retrieving previously stored data to satisfy queries (e.g., jobs/tickets) for solutions to problems while maintaining privacy/security of the data as well as ensuring the quality of the results. In a typical embodiment, a query for a solution to a problem is received and details are extracted therefrom. Using the details, a search is performed on a set of data stored in at least one computer storage device. Based on the search, a set of results will be generated and classified into a set of categories. In any event, the quality of each of the set of results will be assessed based on the usefulness of the set of results. | 07-24-2014 |
Patent application number | Description | Published |
20090259954 | METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR VISUALIZING DATA - A plurality of data attributes are displayed to a user. The user makes a selection of at least two of the attributes. An initial one of the selected attributes is displayed, together with all possible values for the initial one of the selected attributes. The user selects at least one of the possible values for the initial one of the selected attributes. A second one of the selected attributes is displayed, together with all possible values for the second one of the selected attributes that correspond to the selected value of the preceding attribute, along with a corresponding measure for each of the possible values for the second one of the selected attributes | 10-15-2009 |
20090271720 | METHOD FOR DERIVING INTELLIGENCE FROM ACTIVITY LOGS - Techniques for segregating one or more logs of at least one multitasking user to derive at least one behavioral pattern of the at least one multitasking user are provided. The techniques include obtaining at least one of at least one action log, configuration information, domain knowledge, at least one task history and open task repository information, correlating the at least one of at least one action log, configuration information, domain knowledge, at least one task history and open task repository information to determine a task associated with each of one or more actions and segregate the one or more logs based on the one or more actions, and using the one or more logs that have been segregated to derive at least one behavioral pattern of the at least one multitasking user. Techniques are also provided for deriving intelligence from at least one activity log of at least one multitasking user to provide information to the at least one user. | 10-29-2009 |
20090271800 | SYSTEM AND COMPUTER PROGRAM PRODUCT FOR DERIVING INTELLIGENCE FROM ACTIVITY LOGS - Techniques for segregating one or more logs of at least one multitasking user to derive at least one behavioral pattern of the at least one multitasking user are provided. The techniques include obtaining at least one of at least one action log, configuration information, domain knowledge, at least one task history and open task repository information, correlating the at least one of at least one action log, configuration information, domain knowledge, at least one task history and open task repository information to determine a task associated with each of one or more actions and segregate the one or more logs based on the one or more actions, and using the one or more logs that have been segregated to derive at least one behavioral pattern of the at least one multitasking user. Techniques are also provided for deriving intelligence from at least one activity log of at least one multitasking user to provide information to the at least one user. | 10-29-2009 |
20140214884 | MANAGING AND IMPROVING QUESTION AND ANSWER RESOURCES AND CHANNELS - Methods and arrangements for handling user queries. Submitted queries are accessed, and there are identified queries as being insufficiently addressed. A priority is estimated for the identified queries, and the identified queries are ordered based on the estimated priority. A priority-ordered list of queries is provided as output. | 07-31-2014 |
20150149462 | ONLINE THREAD RETRIEVAL USING THREAD STRUCTURE AND QUERY SUBJECTIVITY - Methods and arrangements for handling queries for a discussion thread. A contemplated method includes: receiving a query; automatically classifying the query as subjective, objective or neither; and upon classifying the query as subjective or objective: calculating, for discussion threads of the query, at least one of: a subjectivity score and an objectivity score; determining a degree of relevance to the query of at least one of: the discussion threads, and at least one post in the at least one discussion thread; and ranking the discussion threads based on said calculating and determining. Other variants and embodiments are broadly contemplated herein. | 05-28-2015 |
Patent application number | Description | Published |
20150142719 | AUTOMATICALLY SELF-LEARNING BIDIRECTIONAL SYNCHRONIZATION OF A SOURCE SYSTEM AND A TARGET SYSTEM - A method and associated system for an automatically self-learning audit of a bidirectional synchronization means for synchronizing a source system and a target system. A processor identifies a mismatch between an element of production data of the source system and an analogous production-data element of the target system. If the mismatch is caused by an issue known to the synchronization means, the processor takes corrective action known to resolve the mismatch. Otherwise, the processor attempts to identify a resolution and, if successful, applies the resolution, teaches the resolution to the synchronization mechanism, records the solution, and resends data from the correct system to the incorrect system. If unable to identify a resolution, the processor implements a next-best solution that allows continued operation despite the unresolved mismatch. The processor then generates a report of the mismatch and continues searching for other mismatches in the loaded data models. | 05-21-2015 |
20150142737 | EFFICIENTLY FIRING MAPPING AND TRANSFORM RULES DURING BIDIRECTIONAL SYNCHRONIZATION - A method and associated system for efficiently firing mapping and transform rules during a bidirectional synchronization of two or more systems. A processor loads a set of mapping and transform synchronization rules and a set of cross-reference tables. When an event message received from a source system identifies a revision to an element of the source system's data, the processor parses the message to identify the revised source-system data. The processor uses the cross-references to identify synchronization rules that are associated with the revised data element. If any of the identified rules requires an additional source-system data element or an extrinsic data element located at an external source, the processor retrieves those further identified data elements. The processor then looks up the synchronization procedure of the identified rules, packages it into a synchronization message, and sends the message to the target system. | 05-21-2015 |
20150142740 | AUTOMATICALLY MANAGING MAPPING AND TRANSFORM RULES WHEN SYNCHRONIZING SYSTEMS - A method and associated system for managing rules that synchronize operations of a source system and a target system. A set of linked worksheets is generated as a function of the internal logic of the synchronization rules and of worksheets that represent data models of the source and target systems. These generated worksheets describe and relate data elements of the data models, extrinsic data that is stored externally to the source and target systems, and logical procedures performed by the synchronization rules. When the source data model, the target data model, or a logical procedure is revised, the linked worksheets are updated in response to the revision and these updates automatically propagate across the synchronization rules and across other components of the source system, the target system, and the synchronization mechanism. | 05-21-2015 |
Patent application number | Description | Published |
20120017289 | RAPID METHOD FOR GENERATING GENE KNOCK DOWN MODEL - The present invention provides a novel method of generating knock down models by electroporation of shRNA construct into the testis. The present invention provides an ethically superior, non-surgical, user friendly rapid method for the generation of permanent lines of shRNA knock down non human vertebrates. This invention is ethically superior as it does not involve any loss of animal life and drastically minimizes the production time and use of animals. Current techniques for making knockout models are cumbersome, require trained personnel, costly infrastructure and require hundreds of eggs collected after killing several females. In contrast, this method neither involves any costly infrastructure nor requires trained personnel. The invention also relates to the quick incorporation of shRNA gene construct into the germline of a species so that shRNA is inheritable. The present invention also generates in a single go a variety of knock down models differentially expressing gene specific shRNA, depending on differential shRNA gene incorporation in native genome of various male germ cells, so that there is no restriction in the choice of the gene knock down. | 01-19-2012 |
20120264814 | Isolation, Cloning, Sequencing and Functional analysis of ss-casein promoter along with the regions of exon1, intron1 and exon2 using mammary gland derived cell line of Buffalo (Bubulus bubalis) - The present invention relates to a method of in vitro isolation of buffalo β-caesin promoter (buCSN2) along with the regions of exon1, intron1 and exon2 from the genomic DNA in vitro ( | 10-18-2012 |
20130245228 | Isolation, Cloning, Sequencing and Functional analysis of -casein promoter along with the regions of exon1, intron1 and exon2 using mammary gland derived cell line of Buffalo (Bubulus bubalis) - The present invention relates to a method of in vitro isolation of buffalo β-caesin promoter (buCSN2) along with the regions exon1, intron1 and exon2 from the genomic DNA in vitro ( | 09-19-2013 |
20140018340 | Insulin Mimetic Active Comprising Oxodiperoxo Vanadates and a Pharmaceutical Composition Obtained Thereof - A pharmaceutically acceptable peroxovanadium(v) amine product, DmpzH[VO(02)2](Dmpz)], and its oral as well as injectable use for the treatment of Diabetes mellitus, wherein the said therapeutically stable compound is obtained by reacting V205 or vanadate with hydrogen peroxide and the amine, dimethylpyrazole (Dmpz), at pH 5.5 and temperature 0-4° C. DmpzH[VO(02)2](Dmpz)] is thus poised as a versatile insulin mimic adapted for targeting insulin signaling, stimulating adipogenesis, abrogating insulin stimulated down stream signals thereby lowering the incidence of insulin resistance and type-2 diabetes. | 01-16-2014 |
20140351966 | SHORTCUT PROCEDURE OF TRANSGENE INTEGRATION BY HYPOTONIC SHOCK INTO MALE GERMINAL CELLS FOR GENE EXPRESSION AND TRANSGENESIS - The present invention relates to a new method of gene integration in cells comprising the steps of: preparation of a suspension of poly nucleotide fragments comprising the desired gene in a hypotonic solution; administration of said suspension to cells or tissues; and maintenance of the cells or tissues in vitro or in its normal physiological condition. The invention also relates to a method of generating transgenic animal. | 11-27-2014 |