Maiocchi
Alessandro Maiocchi, Colleretto Giacosa IT
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20110117015 | Diagnostic Agents Selective Against Metalloproteases - The invention relates to aryl-sulphonamido compounds endowed with affinity against metallo proteases MMP, having formula (I) below wherein R, R | 05-19-2011 |
Alessandro Maiocchi, Monza IT
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20130096420 | Process For Preparing Hyperpolarized Substrates And Method For MRI - The present invention generally relates to a process for the preparation of aqueous solutions of hyperpolarized molecules ready for use in in-vivo MR diagnostic imaging, the use thereof as MRI contrast agent in investigation methods for producing diagnostic MR images of a human or non-human animal body organ, region or tissue. | 04-18-2013 |
20140155449 | NEW USE OF L-HISTIDINE AND DERIVATIVES THEREOF - The present invention discloses the use of L-Histidine to reduce Gadolinium accumulation into target organs, preventing its toxic effects, after administration of gadolinium based contrast agents. The invention thus, also disclose the use of L-Histidine to prevent the NSF syndrome in patients with renal functionality impairment. A kit of part is also disclosed by the use of which toxicity associated to free Gd3+, deriving from GDBCA, is prevented by oral administration of L-histidine before administration of the contrast agent. A method for the prevention of toxic metal accumulation which consists in the administration, preferably by the oral route, of L-Histidine is also disclosed. L-Histidine is preferably administered a s a single oral dose comprised from 0.2-20 g. | 06-05-2014 |
20150037261 | New Class Of Diazepine Derivative Chelating Agents And Complexes With Paramagnetic Metals Thereof As MRI Contrast Agents - The present invention relates to a new class of diazepine-derivatives as chelating agents for paramagnetic metal ions, the process for their preparation, and use of such paramagnetic complexes as contrast agents, particularly suitable for Magnetic Resonance Imaging (MRI) analysis. | 02-05-2015 |
20150050218 | Dynamic Contrast Enhanced MRI Method And Agents For The Assessment Of The Macromolecular Transport Within Pathologic Tissues - The present invention generally relates to paramagnetic contrast agents and a Dynamic Contrast Enhanced-MRI method for the non-invasive estimation of the delivery of a macromolecular anticancer drug or pro-drug within pathological tissues and, especially, in solid tumors and for the optimization of anticancer therapies. | 02-19-2015 |
Diego Maiocchi, Milano IT
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20120059265 | Active Transducer Probes and Circuits - In an example embodiment, a method for bidirectional signal propagation comprises: a) sensing a voltage level of a first signal at a first port; b) coupling the first port to an output of an amplifier with a solid state switch if the voltage level of the first signal is less than a threshold voltage, whereby a second signal applied to a second port coupled to an input of the amplifier is propagated in a first direction from the second port to the first port; and c) bypassing the amplifier if the voltage level of the first signal is greater than the threshold voltage such that the first signal is propagated in a second direction from the first port to the second port. | 03-08-2012 |
20140015605 | Active Transducer Probes and Circuits - In an example embodiment, a method for bidirectional signal propagation comprises: a) sensing a voltage level of a first signal at a first port; b) coupling the first port to an output of an amplifier with a solid state switch if the voltage level of the first signal is less than a threshold voltage, whereby a second signal applied to a second port coupled to an input of the amplifier is propagated in a first direction from the second port to the first port; and c) bypassing the amplifier if the voltage level of the first signal is greater than the threshold voltage such that the first signal is propagated in a second direction from the first port to the second port. | 01-16-2014 |
Giuseppe Maiocchi, Capiago Intimiano IT
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20100156687 | CONTROL APPARATUS FOR A LOAD SUPPLY DEVICE - A control apparatus for a supply device of a load, the supply device is of switching type and connected between a supply voltage and a reference voltage, the apparatus including a sigma-delta device having an input terminal at which is present a first digital signal and adapted to provide a pulse-density modulation signal at the output terminal; the sigma-delta device including a feedback circuit capable of sending to the input terminal of the sigma-delta device a second digital signal whose value depends on the value of the output signal, and the apparatus including a device capable of digitalizing the supply voltage and of providing a further digital signal. The feedback circuit includes a terminal capable of receiving the further digital signal, and the sigma-delta device having a gain such that the output digital signal is proportional to the inverse of the further digital signal. | 06-24-2010 |
20120161678 | MANAGEMENT APPARATUS OF A ROTATING MOTOR AND AN ANNEXED LOAD DURING POWER LOSS - A management apparatus is described of a rotating motor and a load during power loss; the apparatus comprises a first switching circuit coupled with the rotating motor and a controller of said first switching circuit. The controller is configured to drive the first switching circuit so as to convert a back-electromotive force voltage developed in the rotating motor into a power supply voltage for the load. The first switching circuit is driven in accordance with a first duty cycle. The apparatus comprises a second switching circuit coupled with the load and driven in accordance with a second duty cycle. The controller is configured to vary said first and said second duty cycles to keep the power supply voltage for the load above or equal to a threshold voltage. | 06-28-2012 |
Giuseppe Maiocchi, Capiago Intimiano (co) IT
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20140217949 | METHOD OF PWM REGULATION OF A CONTINUOUS CURRENT ELECTRIC MOTOR - A method of PWM regulating a motor through a half-bridge drive stage includes sampling the motor current to obtain sampled values during driving intervals or during current decay intervals, and comparing a last sampled value with a current threshold. The motor is coupled in a slow decay electrical path for the duration of a current decay interval if the last sampled value does not exceed the current threshold. Otherwise the motor is coupled in a fast decay electrical path for a portion of the duration of the current decay interval, and is coupled in the slow decay electrical path for a remaining part of the duration of the same current decay interval. | 08-07-2014 |
20140354201 | SWITCHING CONTROLLER FOR ELECTRIC MOTORS AND RELATED METHOD OF CONTROLLING ELECTRIC MOTORS - A switching controller of a poly-phase electric motor may generate, in a fully digital manner, a replica of the phase current and/or of the phase (star) voltage of one or more windings of the motor. The switching controller may use digital signals already available for driving the motor to reconstruct a replica of the phase current or the phase voltage, and thereby avoid the need for dedicated analog components for phase current or phase voltage determination. | 12-04-2014 |