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| 20100220823 | Systems and Methods for Mitigating Self-Induced Far-End Crosstalk - Systems and methods for partial self-FEXT (far-end crosstalk) are described. One method, among others, comprises determining one or more instantaneous characteristics of an input signal, wherein the one or more instantaneous characteristics comprise one or more of amplitude of the input signal and an energy level of the input signal. The method further comprises selecting one or more disturbers to cancel according to the one or more instantaneous characteristics, wherein selecting one or more disturbers is performed on a per-DMT (discrete multi-tone) symbol basis. | 09-02-2010 |
| 20110058468 | Method and apparatus for crosstalk cancellation during SELT testing - A system for performing a single ended line test (SELT) of a selected subscriber line within a bundle of in-service subscriber lines each supporting frequency division multiplexed multi-tone modulated XDSL communications. The system comprises: a crosstalk cancellation module and a SELT module. The crosstalk cancellation module is coupled to the subscriber lines and configured to cancel crosstalk between the selected subscriber line under test and the in-service subscriber lines. The SELT module couples to the crosstalk cancellation module and is configured to coordinate SELT testing with the crosstalk cancellation module to cancel crosstalk between the selected subscriber line and the in-service subscriber lines during testing. | 03-10-2011 |
| 20110235759 | Systems and Methods for Implementing a Multi-Sensor Receiver in a DSM3 Environment - In accordance with one embodiment, a method is implemented in a vectored system for improving a signal-to-noise ratio (SNR) of a far end transmitted signal on a victim line in the system. The method comprises mitigating, by the vectored system, self-induced far-end crosstalk (self-FEXT) on the victim line based on self-FEXT mitigation coefficients and receiving, by a second sensor, information relating to at least one of: self-FEXT of the vectored system, external noise, and the far end transmitted signal. The method further comprises learning, at the second sensor, coefficients relating to self-FEXT coupling into the second sensor and removing self-FEXT from the second sensor based on the learned coefficients. Upon removal of self-FEXT from the second sensor, a linear combiner configured to combine information relating to the victim line and the second line is learned. The method further comprises applying the learned linear combiner and readjusting the self-FEXT mitigation coefficients to remove any residual self-FEXT on the victim line after application of the learned linear combiner. | 09-29-2011 |
| 20120020418 | REDUCED MEMORY VECTORED DSL - The memory storage, transmission and processing demands of a vectored DSL system are reduced by sampling a subset of DSL tones in the DSL tone range used in the vectored system. This data is smoothed (denoised) to further reduce the data's size, sacrificing some fidelity or precision as a result. Finally, lossless entropy coding or the like is performed to encode the FEXT cancellation data for storage and use. The resulting data is less likely to cause transmission bottlenecks in the vectored system, can be stored and used more efficiently for both on-chip and off-chip vectoring implementations, and can be readily updated in various ways. | 01-26-2012 |
| 20140056396 | SYSTEMS AND METHODS FOR IMPLEMENTING A MULTI-SENSOR RECEIVER IN A DSM3 ENVIRONMENT - In accordance with one embodiment, a method is implemented in a vectored system for improving a signal-to-noise ratio (SNR) of a far end transmitted signal on a victim line in the system. The method comprises mitigating, by the vectored system, self-induced far-end crosstalk (self-FEXT) on the victim line based on self-FEXT mitigation coefficients and receiving, by a second sensor, information relating to at least one of: self-FEXT of the vectored system, external noise, and the far end transmitted signal. The method further comprises learning, at the second sensor, coefficients relating to self-FEXT coupling into the second sensor and removing self-FEXT from the second sensor based on the learned coefficients. Upon removal of self-FEXT from the second sensor, a linear combiner configured to combine information relating to the victim line and the second line is learned. | 02-27-2014 |
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| 20150128947 | PORTABLE HANDHELD PRESSURE SUPPORT SYSTEM AND METHOD - The present disclosure pertains to a portable handheld pressure support system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The pressure support system is configured to treat COPD and/or other patients suffering from dyspnea and/or other conditions. The pressure support system is configured to be small and lightweight so that a subject may carry the system and use the system as needed without requiring a device to be worn on the face. The present disclosure contemplates that the portable handheld pressure support system may be used to treat symptoms and/or conditions related to dyspnea, and/or for other uses. In one embodiment, the system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components. | 05-14-2015 |
| 20150136129 | PORTABLE HANDHELD BLENDING GAS ENRICHED PRESSURE SUPPORT SYSTEM AND METHOD - The present disclosure pertains to a portable handheld pressure support system configured to deliver a blending gas enriched pressurized flow of breathable gas to the airway of a subject. The pressure support system is configured to treat patients suffering from dyspnea and/or other conditions. The therapy provided to dyspnea patients is configured to be used as needed by a subject to rapidly alleviate shortness of breath. The pressure support system is configured to be small and lightweight so that the subject may carry the system and use the system as needed without requiring a device to be worn on the face. In some embodiments, the system comprises one or more of a pressure generator, a subject interface, a blending gas inlet port, one or more sensors, a valve, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components. | 05-21-2015 |
| 20150283339 | HANDHELD DYSPNEA TREATMEENT DEVICE WITH DRUG AND GAS DELIVERY - A portable handheld pressure support system ( | 10-08-2015 |
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| 20080221146 | INHIBITORS OF NUCLEOPHOSMIN (NPM) AND METHODS FOR INDUCING APOPTOSIS - Nucleophosmin inhibitors are disclosed which inhibit the multimerization of nucleophosmin and the biological activity of nucleophosmin, such as the ability of nucleophosmin to inhibit apoptosis and inhibit cellular differentiation. These small molecule inhibitors are useful for treating diseases and disorders, such as cancer associated with dysregulated nucleophosmin expression. Methods for identifying small molecule inhibitors of nucleophosmin involving multimerization sites for nucleophosmin are also disclosed. An exemplary small molecule inhibitor of nucleophosmin is NSC348884 which has the following chemical structure: | 09-11-2008 |
| 20090099165 | Protein Kinase Inhibitors - Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: | 04-16-2009 |
| 20090143399 | Protein Kinase Inhibitors - Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: | 06-04-2009 |
| 20110144066 | SMALL MOLECULE INHIBITORS OF THE PLECKSTRIN HOMOLOGY DOMAIN AND METHODS FOR USING SAME - Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein. | 06-16-2011 |
| 20110212929 | Protein Kinase Inhibitors - Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: | 09-01-2011 |
| 20120039885 | COMPOSITION AND METHOD FOR CANCER TREATMENT - Anti-CEACAM6 antibodies and antibody fragments, nucleic acids encoding them, methods of their manufacture, and methods to treat cancer using these compounds are provided. | 02-16-2012 |
| 20130302303 | PROTEIN KINASE INHIBITORS - Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: | 11-14-2013 |
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| 20080264464 | Temperature Control Including Integrated Thermoelectric Sensing and Heat Pumping Devices and Related Methods and Systems - A temperature control system may include a thermoelectric device, and a controller electrically coupled to the thermoelectric device. The controller may be configured to apply an AC signal to the thermoelectric device, and to sense an electrical characteristic of the thermoelectric device using the AC signal. The controller may also be configured to generate an electrical control signal to pump heat through the thermoelectric device responsive to sensing the electrical characteristic of the thermoelectric device using the AC signal. Related methods are also discussed. | 10-30-2008 |
| 20090205696 | Thermoelectric Heat Pumps Providing Active Thermal Barriers and Related Devices and Methods - An electronic device may include a heat generating component and a surface adjacent the heat generating component. A temperature of the heat generating component may be greater than a temperature of the surface adjacent the heat generating component during operation of the electronic device. A thermoelectric heat pump between the surface and the heat generating component may be configured to pump heat from a cold side of the thermoelectric heat pump adjacent the surface toward the heat generating component. Related methods are also discussed. | 08-20-2009 |
| 20100252087 | THERMOELECTRIC DEVICES INCLUDING THERMOELECTRIC ELEMENTS HAVING OFF-SET METAL PADS AND RELATED STRUCTURES, METHODS, AND SYSTEMS - A thermoelectric device may include a thermoelectric element including a layer of a thermoelectric material and having opposing first and second surfaces. A first metal pad may be provided on the first surface of the thermoelectric element, and a second metal pad may be provided on the second surface of the thermoelectric element. In addition, the first and second metal pads may be off-set in a direction parallel with respect to the first and second surfaces of the thermoelectric element. Related methods are also discussed. | 10-07-2010 |
| 20110132000 | Thermoelectric Heating/Cooling Structures Including a Plurality of Spaced Apart Thermoelectric Components - A thermoelectric heating/cooling structure may include a heat exchanger and a heat spreader spaced apart from the heat exchanger. In addition, a plurality of spaced apart thermoelectric components may be thermally coupled in parallel between the heat exchanger and the heat spreader. More particularly, each of the thermoelectric components may include a first header adjacent the heat exchanger, a second header adjacent the heat spreader, and a plurality of thermoelectric elements thermally coupled in parallel between the first and second headers. The first headers of the thermoelectric components may be spaced apart adjacent the heat exchanger, and the second headers of the thermoelectric components may be spaced apart adjacent the heat spreader. | 06-09-2011 |
| 20110220162 | Thermoelectric (TE) Devices/Structures Including Thermoelectric Elements with Exposed Major Surfaces - A thermoelectric structure may include a thermally conductive substrate, and a plurality of thermoelectric elements arranged on a surface of the thermally conductive substrate. Moreover, each thermoelectric element may be non-parallel and non-orthogonal with respect to the surface of the thermally conductive substrate. For example, each of thermoelectric elements may be a planar thermoelectric element, and a plane of each of the thermoelectric elements may be oriented obliquely with respect to the surface of the thermally conductive substrate. | 09-15-2011 |
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| 20090004288 | STABILIZED OPHTHALMIC SOLUTIONS - The present invention relates to stabilized ophthalmic solutions comprising at least one peroxide. In one embodiment, the present invention relates to an ophthalmic solution comprising a pH between about 6 and about 8 and about 50 to about 1000 ppm hydrogen peroxide and about 0.005 wt % (50 ppm) to about 0.05 wt % (500 ppm) at least one salt of diethylenetriamine pentaacetic acid selected from the group consisting of calcium salts of diethylenetriamine pentaacetic acid, zinc salts of diethylenetriamine pentaacetic acid and mixed calcium/zinc salts of diethylenetriamine pentaacetic acid. | 01-01-2009 |
| 20090072206 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS - Various non-limiting embodiments disclosed herein relate to ophthalmic devices comprising photochromic materials having extended pi-conjugated systems. For example, various non-limiting embodiments disclosed herein provide a photochromic material, such as an indeno-fused naphthopyran, which comprises a group that extends the pi-conjugated system of the indeno-fused naphthopyran bonded at the 11-position of thereof. Further, the photochromic materials according to certain non-limiting embodiments disclosed herein may display hyperchromic absorption of electromagnetic radiation as compared to conventional photochromic materials and/or may have a closed-form absorption spectrum that is bathochromically shifted as compared to conventional photochromic materials. Other non-limiting embodiments relate to methods of making the ophthalmic devices comprising photochromic materials. | 03-19-2009 |
| 20090168014 | LASER ENHANCED LENS - This invention discloses methods and apparatus for modifying a silicone contact lens via laser ablation and a resulting modified lens. In some embodiments a lens is ablated in a hydrated state. A lens may also be ablated in an environment of decreased oxygen content. | 07-02-2009 |
| 20090239775 | OPHTHALMIC SOLUTIONS DISPLAYING IMPROVED EFFICACY - The present invention relates to ophthalmic compositions comprising a pH between about 6 and about 8 and about 50 to about 1000 ppm hydrogen peroxide, about 100 ppm to about 2000 ppm of at least one chlorite compound and about 20 to 100 ppm of at least one saturated, polymeric quaternium salt. The ophthalmic compositions of the present invention display improved antifungal efficacy against | 09-24-2009 |
| 20090324691 | METHODS AND OPHTHALMIC DEVICES USED IN THE TREATMENT OF OCULAR ALLERGIES - Ophthalmic devices containing anti-allergic agents and methods of preparing the same are disclosed herein. | 12-31-2009 |
| 20100151123 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES - The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one acyclic polyamide. | 06-17-2010 |
| 20110139995 | METHODS AND DEVICES TO TEST DIFFUSION RATES OF OCULAR DRUG DELIVERY SYSTEMS - Methods of detecting the discharge and uptake rates of ophthalmic lenses containing pharmaceutical agents are disclosed herein. | 06-16-2011 |
| 20110181835 | LASER ENHANCED LENS - This invention discloses methods and apparatus for modifying a silicone contact lens via laser ablation and a resulting modified lens. In some embodiments a lens is ablated in a hydrated state. A lens may also be ablated in an environment of decreased oxygen content. | 07-28-2011 |
| 20110201596 | Methods for Providing Oxidatively Stable Ophthalmic Compositions - This invention relates to a process for improving the stability of an ophthalmically compatible solution comprising at least one oxidatively unstable ophthalmic compound. | 08-18-2011 |
| 20110275734 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME - The present invention relates to compositions comprising at least one stable, near-monodisperse, non-reactive hydrophilic polymer comprising in said polymer's backbone, a hydrophilic segment having a degree of polymerization of about 10 to about 1000, and a linear silicone segment at least one terminal end of said non-reactive hydrophilic polymer, wherein said silicone segment comprises between about 6 and about 200 siloxy units, and said non-reactive hydrophilic polymer is associated, via the linear silicone block with a silicone hydrogel. The non-reactive hydrophilic polymers may be incorporated into the formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post formation. | 11-10-2011 |
| 20110294914 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES - The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one acyclic polyamide. | 12-01-2011 |
| 20120277444 | SYNTHESIS OF HYDROXYALKYL AMIDES FROM ESTERS - Hydroxyamides are synthesized from esters. A process of making hydroxyalkyl amides comprises: reacting an ester with a hydroxyalkyl amine having the formula H | 11-01-2012 |
| 20120283353 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 11-08-2012 |
| 20130175722 | PROCESS FOR MAKING OPHTHALMIC LENSES - The present invention relates to aqueous processes for the production of silicone hydrogel contact lenses. | 07-11-2013 |
| 20130184372 | SILICONE POLYMERS COMPRISING SULFONIC ACID GROUPS - The present invention relates to a silicone polymer comprising a sulfonic acid component formed from reactive components comprising (i) at least one silicone component and (ii) at least one sulfonic acid-containing component, wherein the sulfonic acid-containing component is comprised of a non-polymerizable, hydrophobic cation and a polymerizable sulfonic acid. | 07-18-2013 |
| 20130203812 | IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NUTRICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY - The present invention relates to ionic silicone hydrogel polymers displaying improved thermal stability. More specifically, the present invention relates to a polymer formed from reactive components comprising at least one silicone component and at least one ionic component comprising at least one anionic group. The polymers of the present invention display good thermal stability and desirable protein uptake. | 08-08-2013 |
| 20130203813 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers comprising at least one pharmaceutical or nutriceutical component and displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 08-08-2013 |
| 20130217620 | IONIC SILICONE HYDROGELS - The present invention relates to ionic silicone hydrogel contact lenses which comprise at least one pharmaceutical or nutriceutical component and are formed from reaction mixtures comprising a mixture of slow-reacting hydrophilic monomers, including at least one slow-reacting ionic monomer, at least one silicone-containing component and at least one hydroxyl-containing component, wherein the ratio of the slow-reacting hydrophilic component half lives to the silicone-containing component half life is at least 2. | 08-22-2013 |
| 20130341811 | LENS COMPRISING LOW AND HIGH MOLECULAR WEIGHT POLYAMIDES - The present invention relates to a contact lens formed from components including (i) at least one silicone component, (ii) at least one low molecular weight polyamide having a weight average molecular weight of less than 200,000, and (iii) at least one high molecular weight polyamide having a weight average molecular weight of greater than 200,000, wherein the low molecular weight polyamide does not contain a reactive group. | 12-26-2013 |
| 20130345364 | METHOD OF MAKING SILICONE CONTAINING CONTACT LENS WITH REDUCED AMOUNT OF DILUENTS - The present invention relates to a method of manufacturing a contact lens including the steps of: (i) adding reactive components to a mold, wherein the reactive components comprise (a) at least one hydroxy-containing silicone component having a weight average molecular weight from about 200 to about 15,000 g/mole and (b) at least one mono-ether terminated, mono-methacrylate terminated polyethylene glycol having a weight average molecular weight from about 200 to about 10,000 g/mole; (ii) curing the reactive components within the mold to form the contact lens; and (iii) removing the contact lens from said mold. | 12-26-2013 |
| 20140011843 | METHODS FOR STABILIZING OXIDATIVELY UNSTABLE COMPOSITIONS - Ophthalmic compositions and methods of preparing such compositions are disclosed. | 01-09-2014 |
| 20140275434 | SILICONE-CONTAINING CONTACT LENS HAVING REDUCED AMOUNT OF SILICON ON THE SURFACE - The present invention relates to a method of reducing the amount of silicon on a surface of a contact lens, wherein the method includes reacting the surface of a contact lens containing at least one silicone component with a fluoride reagent. | 09-18-2014 |
| 20140329859 | IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NEUTICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY - The present invention relates to ionic silicone hydrogel polymers displaying improved thermal stability. More specifically, the present invention relates to a polymer formed from reactive components comprising at least one silicone component and at least one ionic component comprising at least one anionic group. The polymers of the present invention display good thermal stability and desirable protein uptake. | 11-06-2014 |
| 20150185365 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers comprising at least one pharmaceutical or nutriceutical component and displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 07-02-2015 |
| 20150198744 | POLYMERS COMPRISING SULFONIC ACID GROUPS - The present invention relates to a polymers and hydrogels comprising a sulfonic acid component formed from reactive components comprising (i) at least one hydrophobic monomer and (ii) at least one sulfonic acid-containing component, wherein the sulfonic acid-containing component is comprised of a salt formed by a non-polymerizable, hydrophilic base and a polymerizable sulfonic acid. One or more embodiments provide that the at least one hydrophobic monomer comprises a silicone component. | 07-16-2015 |
| 20150241601 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS - Various non-limiting embodiments of the present disclosure relate to ophthalmic devices comprising photochromic materials comprising a reactive substituent. For example, the present disclosure contemplates ophthalmic devices comprising photochromic materials, such as photochromic naphthopyrans and indeno-fused naphthopyrans having a reactive substituent comprising a reactive moiety linked to the photochromic naphthopyran by one or more linking groups. In certain non-limiting embodiments, the reactive moiety comprises a polymerizable moiety. In other non-limiting embodiments, the reactive moiety comprises a nucleophilic moiety. Other non-limiting embodiments of the present disclosure relate to methods of making the photochromic ophthalmic device, wherein the photochromic ophthalmic devices comprise the photochromic naphthopyrans described herein. | 08-27-2015 |
| 20150378057 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 12-31-2015 |
| 20160054589 | METHODS AND APPARATUS TO FORM SEPARATORS FOR BIOCOMPATIBLE ENERGIZATION ELEMENTS FOR BIOMEDICAL DEVICES - Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities composing active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements. | 02-25-2016 |
| 20160056494 | METHODS TO FORM BIOCOMPATIBLE ENERGIZATION ELEMENTS FOR BIOMEDICAL DEVICES COMPRISING LAMINATES AND DEPOSITED SEPARATORS - Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry and depositing separators within a laminate structure of the battery. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements. | 02-25-2016 |
