Maddalena
Maddalena Adorno, Monte San Pietro IT
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20120035069 | PROGNOSIS OF BREAST CANCER PATIENTS BY MONITORING THE EXPRESSION OF TWO GENES - The present invention relates to the expression of two genes, CyclinG2 and Sharp1, which correlates with prognosis in individuals having breast cancer. Specifically, this invention provides a method to stratify samples from breast cancer patients in a high or low recurrence risk in the years following primary tumor removal. This classification can be achieved through the analysis of protein or mRNA expression levels for the two identified genes. The invention also illustrates how CyclinG2 and Sharp1 have been identified in mammary cancer cell lines and validated in a large cohort of human patients as powerful metastasis predictors. | 02-09-2012 |
20150322533 | PROGNOSIS OF BREAST CANCER PATIENTS BY MONITORING THE EXPRESSION OF TWO GENES - The present invention relates to the expression of two genes, CyclinG | 11-12-2015 |
Maddalena Adorno, Palo Alto, CA US
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20160046946 | TARGETING CHROMATIN MODIFIERS FOR THE TREATMENT OF MEDICAL CONDITIONS - Methods and compositions are provided for the treatment of medical conditions associated with a reduced rate of stem cell self-renewal or that will be responsive to an increased rate of stem cell self-renewal. Aspects of the methods include inhibiting H2A deubiquitinating enzyme activity in cells, e.g. by administering an effective amount of an H2A deubiquitinating enzyme antagonist. Also provided are screens to identify therapeutics for the treatment of medical conditions associated with a reduced rate of stem cell self-renewal or that will be responsive to an increased rate of stem cell self-renewal. | 02-18-2016 |
Maddalena Belluce, Bologna IT
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20140138351 | Method For Making A Silicon Separation Microcolumn For Chromatography Or Gas Chromatography - A method for the production of a separation microcolumn made in silicon wafer ( | 05-22-2014 |
Maddalena Cirani, Goteborg SE
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20130026872 | ROTOR OF AN ELECTRIC MACHINE WITH EMBEDDED PERMANENT MAGNETS AND ELECTRIC MACHINE - A rotor for an electric machine excited by magnetic poles formed by one or more embedded permanent magnets includes a magnetic body and the one or more embedded permanent magnets associated with the magnetic body defining first magnetic poles and second magnetic poles of alternating magnetic polarity along a rotor direction. For at least one of the one or more embedded permanent magnets a rotor segment is arranged between the one or more embedded permanent magnets and a first surface of the magnetic body. At least one retainer element connects the rotor segment to a portion of the magnetic body. | 01-31-2013 |
Maddalena Martigli, Capraia E. Limite IT
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20130140427 | SYSTEM OF DISPOSABLE MOULDS USED TO MAKE-UP MODULAR FORMWORKS TO BUILD-UP CONCRETE WALLS FEATURING COMPLEX SHAPES - System of disposable moulds for the realization of modular formworks to contain and modelize vertical concrete castings, comprising one basic element and a plurality of special elements, such as to let a limited quantity of cement mixture come out, suitable for being spread on the formwork faces to trim it. | 06-06-2013 |
Maddalena Mastrogiacomo, Genova IT
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20100203101 | BIO-MEMBRANE FOR TISSUE REGENERATION - A bio-membrane with angiogenic activity for implant in tissue regeneration and repair, including bone reconstruction and the repair of skin and soft tissue lesions is described, essentially constituted by a gel able to provide support and growth and/or differentiation and/or angiogenic factors for the full in vivo functionality of the cell, containing also mesenchymal stem/precursor cells, an implant device for reconstructive surgery of bone tissue, of skin and soft tissue lesions which comprises the bio-membrane, and a method for its obtainment. Use of the gel alone for tissue regeneration and of adhesive plasters that comprise it is also described. | 08-12-2010 |
20120141559 | BIO-MEMBRANE FOR TISSUE REGENERATION - A bio-membrane with angiogenic activity for implant in tissue regeneration and repair, including bone reconstruction and the repair of skin and soft tissue lesions is described, essentially constituted by a gel able to provide support and growth and/or differentiation and/or angiogenic factors for the full in vivo functionality of the cell, containing also mesenchymal stem/precursor cells, an implant device for reconstructive surgery of bone tissue, of skin and soft tissue lesions which comprises the bio-membrane, and a method for its obtainment. Use of the gel alone for tissue regeneration and of adhesive plasters that comprise it is also described. | 06-07-2012 |
Maddalena Mastrogiacomo, Genova (ge) IT
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20150299651 | CELL CULTURE SUPPLEMENTS - The invention relates to cell culture supplements based on a platelet rich plasma fraction and a platelet poor plasma fraction. The supplements increase cell proliferation rate, improve selection of clonogenic cells, proliferation of cells from biopsies from elderly patients, maintenance of cell differentiation potential, and in vitro expansion of cell cultures also starting from an extremely low number of initially plated cells. The supplements may be freeze-dried and kept for long period of time as a quality controlled “off the shelf” product. | 10-22-2015 |
Maddalena Violetti, Lausanne CH
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20130068024 | DEVICE AND METHOD FOR MONITORING ROTOR BLADES OF A TURBINE - A device and a method for monitoring the operational state of rotor blades of a turbine from a position facing the blade tip of a passing rotor blade: A wavesource generates an electromagnetic wave and a wave guide directs the wave towards the blade tip. The waveguide is included in a resonator defining at least one discrete resonance frequency of the wave on the waveguide. An aperture at its front end emits an energy fraction of the wave toward the blade tip. The frequency of the wave is adjusted to the resonance frequency of the resonator at the momentary operation conditions, and a measuring unit compares at least one measurement parameter of the wave directed towards the blade tip with the corresponding measurement parameter of the wave reflected from the blade tip. | 03-21-2013 |