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| 20160139883 | DISTRIBUTING RESOURCE REQUESTS IN A COMPUTING SYSTEM - In an embodiment, a method include, in a hardware processor, producing, by a block of hardware logic resources, a constrained randomly generated or pseudo-randomly generated number (CRGN) based on a bit mask stored in a register memory. | 05-19-2016 |
| 20160139950 | SHARING RESOURCES IN A MULTI-CONTEXT COMPUTING SYSTEM - In an embodiment, a method of providing quality of service (QoS) to at least one resource of a hardware processor includes providing, in a memory of the hardware processor, a context including at least one quality of service parameter and allocating access to the at least one resource of the hardware processor based on the quality of service parameter of the context, a device identifier, a virtual machine identifier, and the context. | 05-19-2016 |
| 20160140043 | INSTRUCTION ORDERING FOR IN-PROGRESS OPERATIONS - Execution of the memory instructions is managed using memory management circuitry including a first cache that stores a plurality of the mappings in the page table, and a second cache that stores entries based on virtual addresses. The memory management circuitry executes operations from the one or more modules, including, in response to a first operation that invalidates at least a first virtual address, selectively ordering each of a plurality of in progress operations that were in progress when the first operation was received by the memory management circuitry, wherein a position in the ordering of a particular in progress operation depends on either or both of: (1) which of one or more modules initiated the particular in progress operation, or (2) whether or not the particular in progress operation provides results to the first cache or second cache. | 05-19-2016 |
| 20160140048 | CACHING TLB TRANSLATIONS USING A UNIFIED PAGE TABLE WALKER CACHE - A core executes memory instructions. A memory management unit (MMU) coupled to the core includes a first cache that stores a plurality of final mappings of a hierarchical page table, a page table walker that traverses levels of the page table to provide intermediate results associated with respective levels for determining the final mappings, and a second cache that stores a limited number of intermediate results provided by the page table walker. The MMU compares a portion of the first virtual address to portions of entries in the second cache, in response to a request from the core to invalidate a first virtual address, based on a match criterion that depends on the level associated with each intermediate result stored in an entry in the second cache, and removes any entries in the second cache that satisfy the match criterion. | 05-19-2016 |
| 20160140059 | MULTIPLE MEMORY MANAGEMENT UNITS - In an embodiment, interfacing a pipeline with two or more interfaces in a hardware processor includes providing a single pipeline in a hardware processor. The single pipeline presents at least two visible units. The single pipeline includes replicated architecturally visible structures, shared logic resources, and shared architecturally hidden structures. The method further includes receiving a request from one of a plurality of interfaces at one of the visible units. The method also includes tagging the request with an identifier based on the one of the at least two visible units that received the request. The method further includes processing the request in the single pipeline by propagating the request through the single pipeline through the replicated architecturally visible structures that correspond with the identifier. | 05-19-2016 |
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| 20130064434 | BIOMETRIC FEATURE EXTRACTION USING MULTIPLE IMAGE INSTANTIATIONS - Systems and methods acquire and/or generate multiple different images of the same biometric identity, identify specific instances of biometric features in each of the different images, and merge the identified specific instances of biometric features into a data record that provides a digital representation of the biometric identity. Examples of biometric identities include fingerprints, handprints, palm prints, and thumbprints. In one embodiment, a counter is associated with each specific instance of a biometric feature found in the multiple images. Specific instances of biometric features found most frequently have high counts and are indicative of true identifications; those with low counts are indicative of false identifications. A threshold distinguishes between true and false identifications. Those specific instances with counts below the threshold are excluded when the digital representation of the biometric identity is generated. Thus, the methodology eliminates false identifications of specific instances of biometric features while accentuating true identifications. | 03-14-2013 |
| 20140369575 | SYSTEM AND METHOD OF CAPTURING AND PRODUCING BIOMETRIC-MATCHING QUALITY FINGERPRINTS AND OTHER TYPES OF DACTYLOGRAPHIC IMAGES WITH A MOBILE DEVICE - An optical module includes a housing with a lighting mechanism, an aperture formed therein, and a window that frames a transparent surface adapted to contact a skin surface of a person, for example, a fingertip. The lighting mechanism provides light to illuminate the skin surface placed upon the transparent surface. A prism has a first side facing the lighting mechanism, a second side at the window, and a third side through which a dactylographic image exits the prism. One or more light reflecting surfaces are disposed within the housing to reflect the dactylographic image towards the housing aperture. The optical module is coupled to a mobile device having a camera, with the aperture of the housing aligning with a lens of the camera. The camera acquires the dactylographic image, and the mobile device adjusts this dactylographic image to produce a dactylographic image suitable for biometric matching. | 12-18-2014 |
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| 20100178505 | FIBERS AND FIBER-BASED SUPERSTRUCTURES, THEIR PREPARATION AND USES THEREOF - This invention is directed to fibers comprising copolymers or homopolymer blends, superstructures comprising said fibers, process for the preparation of the same and uses thereof. The fibers of this invention have long range order and superstructures produced from said fibers can be used in applications including but not limited to membranes, filtration media, high surface area substrates for sensors and catalysis, stents, tissue scaffolds and drug delivery. | 07-15-2010 |
| 20110240550 | BLOCK COPOLYMER MEMBRANES AND ASSOCIATED METHODS FOR MAKING THE SAME - A separation matrix comprises a porous surface layer; and a bulk porous support, wherein both the porous surface layer and the bulk porous support comprising a block copolymer. The block copolymer comprises A-B or A-B-A repeating units, wherein A and B at each occurrence are two different blocks of oligomer, or polymer. A structural unit of block A is derived from one or more atom transfer radical polymerization (ATRP)-active monomer or oligomer and a structural unit of block B is derived from a thermoplastic ATRP-active macro initiator. A poly dispersity index of the block copolymer is at least about 2. | 10-06-2011 |
| 20120308650 | MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY - Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers. | 12-06-2012 |
| 20130302401 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF - A new class of poly(beta-amino alcohols) (PBAAs) has been prepared using combinatorial polymerization. The inventive PBAAs may be used in biotechnology and biomedical applications as coatings (such as coatings of films or multilayer films for medical devices or implants), additives, materials, excipients, non-biofouling agents, micropatterning agents, and cellular encapsulation agents. When used as surface coatings, these PBAAs elicited different levels of inflammation, both in vitro and in vivo, depending on their chemical structures. The large chemical diversity of this class of materials allowed us to identify polymer coatings that inhibit macrophage activation in vitro. Furthermore, these coatings reduce the recruitment of inflammatory cells, and reduce fibrosis, following the subcutaneous implantation of carboxylated polystyrene microparticles. These polymers may be used to form polyelectrolyte complex capsules for cell encapsulation. The invention may also have many other biological applications such as antimicrobial coatings, DNA or siRNA delivery, and stem cell tissue engineering. | 11-14-2013 |
| 20140271843 | Multi-Layer Hydrogel Capsules for Encapsulation of Cells and Cell Aggregates - Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject. | 09-18-2014 |
| 20160137785 | POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF - A new class of poly(beta-amino alcohols) (PBAAs) has been prepared using combinatorial polymerization. The inventive PBAAs may be used in biotechnology and biomedical applications as coatings (such as coatings of films or multilayer films for medical devices or implants), additives, materials, excipients, non-biofouling agents, micropatterning agents, and cellular encapsulation agents. When used as surface coatings, these PBAAs elicited different levels of inflammation, both in vitro and in vivo, depending on their chemical structures. The large chemical diversity of this class of materials allowed us to identify polymer coatings that inhibit macrophage activation in vitro. Furthermore, these coatings reduce the recruitment of inflammatory cells, and reduce fibrosis, following the subcutaneous implantation of carboxylated polystyrene microparticles. These polymers may be used to form polyelectrolyte complex capsules for cell encapsulation. The invention may also have many other biological applications such as antimicrobial coatings, DNA or siRNA delivery, and stem cell tissue engineering. | 05-19-2016 |
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| 20140125196 | Polymer Composite Actuator and Generator Driven by Water Gradients - Water-responsive composite materials are provided containing a polymeric matrix and a water-responsive gel integrated into the polymeric matrix. The water-responsive gel can include a polyol or an alkoxylated polyol crosslinked by reversibly hydrolysable bonds, such as borate ester bonds. The polymeric matrix can include conjugated polymers such as poly(pyrrole) containing polymers. The composite material is capable of rapid actuation in the presence of a water gradient and can exhibit power densities greater than 1 W/kg. Methods of making water-responsive composite materials are provided, including by electropolymerization. Devices containing water-responsive composite materials are provided for sensing, locomotion, and power generation. | 05-08-2014 |
| 20160022835 | Targeted Polymeric Inflammation-Resolving Nanoparticles - Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation. | 01-28-2016 |
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| 20140266324 | High Electron Mobility Transistor with Multiple Channels - A device includes a source and a drain for transmitting and receiving an electronic charge. The device also includes a first stack and a second stack for providing at least part of a conduction path between the source and the drain, wherein the first stack includes a first gallium nitride (GaN) layer of a first polarity, and the second stack includes a second gallium nitride (GaN) layer of the second polarity, and wherein the first polarity is different from the second polarity. At least one gate operatively connected to at least the first stack for controlling a conduction of the electronic charge, such that, during an operation of the device, the conduction path includes a first two-dimensional electron gas (2DEG) channel formed in the first GaN layer and a second 2DEG channel formed in the second GaN layer. | 09-18-2014 |
| 20140285264 | Reconfigurable Output Matching Network for Multiple Power Mode Power Amplifiers - An impedance matching network for a radio frequency (RF) amplifier includes multiple stages connected to each other in a first to last order. A first stage produces an RE output signal, and a last stage receives an RF input signal. Each stage includes a first inductor connected to produce an output signal, a second inductor connected to receive an input signal from a next stage, a capacitor connected between the first and second inductors and a ground. In addition, each stage other than the first stage further includes a first switch to by-pass the first and second inductors, a second switch connected between the first and second inductors and the ground, and a controller for controlling, the first and second switches to select a particular power level of a set of power levels. | 09-25-2014 |
| 20150117512 | System and Method for Linearizing Power Amplifiers - A power encoder includes an amplitude-phase splitter for splitting an input signal into an envelope signal and a phase modulated signal, and a pre-distortion unit for distorting the envelope signal using a look-up table (LUT) to produce a distorted envelope signal. The power encoder also includes a digital converter for combining the distorted envelope signal with the phase modulated signal to produce a distorted input signal, a pulse width modulator (PWM) for modulating the distorted input signal according to the transformation function to produce a modulated signal, and a switch mode power amplifier for amplifying the modulated signal. The look-up table stores a non-linear mapping of a transformation function and a relationship between the distorted input signal and the modulated signal is non-linear. | 04-30-2015 |
| 20150357989 | Output Matching Network for Wideband Power Amplifier with Harmonic Suppression - A wideband harmonic trap includes a first resonant tank in the form of a parallel LC circuit, and a second resonant tank in the form of a series LC circuit. The LC circuits are connected to it common input, an output of the parallel LC circuit is connected to a load and to ground via a shunt capacitor, and an output of the series LC circuit is connected to the ground. | 12-10-2015 |
| 20160028565 | System and Method for Linearizing Power Amplifiers - A power encoder includes a pulse width modulator for modulating a signal according to a set of thresholds to produce a pulse width modulated (PWM) signal and a switch mode power amplifier for amplifying the PWM signal by switching states of switching devices according to amplitudes of the PWM signal. At least one or combination of a distribution of values of the voltage thresholds in the set and a distribution of values of a current generated by different switching devices are non-uniform. The set of voltage thresholds includes at least two positive voltage thresholds. | 01-28-2016 |
| 20160087585 | Wideband Self-Envelope Tracking RF Power Amplifier - A wideband self-envelope tracking power amplifier (PA) can use more than a 40-MHz channel bandwidth and improves the envelope bandwidth limit of a self-envelope tracking PAs by ten times. The PA uses an envelope load network, which is based on a general multi-stage low-pass filter. The envelope load network located between an RF choke inductor and main DC power supply provides a dynamically modulated PA supply voltage without using a dedicated envelope amplifier. An input terminal of the network connects a main PA via an RF choke inductor to an input of low-pass filter. An output terminal is connected to the low-pass filter via an envelope choke inductor and to a direct current (DC) power supply. A DC blocker is connected between the output of the low-pass filter and ground by a termination resistor. | 03-24-2016 |
| 20160099661 | Method to Generate Multilevel Inverter Modulation Control Signals - A method generates space vector modulation signals for a multi-level power inverter using space vector pulse width modulation (SVPWM). A reference voltage and a triangle region for the reference voltage are determined. Vertices for a space vector that is closest to the reference voltage is outputted. Then, the vertices are adjusted so that the space vector is in a valid region of the triangle region. Lastly, the space vector modulation signals a, b, and c corresponding to the space vector in the valid region are outputed. | 04-07-2016 |
| 20160134446 | System and Method for Linearizing Power Amplifiers - A power encoder includes a pulse width modulator for modulating a signal according to a set of thresholds to produce a pulse width modulated (PWM) signal and a switch mode power amplifier for amplifying the PWM signal by switching states of switching devices according to amplitudes of the PWM signal. At least one or combination of a distribution of values of the voltage thresholds in the set and a distribution of values of a current generated by different switching devices are non-uniform. The set of voltage thresholds includes at least two positive voltage thresholds. | 05-12-2016 |
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| 20090010263 | MoCA frame bundling and frame bursting - A system and method are provided for aggregating Multimedia over Coax Alliance (MoCA) Medium Access Control (MAC) frames. The method sends a Multiframe Reservation Request (MRR) requesting a transmission time slot, and receives a grant in response to the MRR. Subsequent to sending the MRR, a plurality of MoCA MAC frames are accepted and assembled into a physical layer (PHY) burst packet that is transmitted in the granted time slot. A method is also provided for bundling client data packets into a MoCA MAC frame. The method sends a Bundledpacket Reservation Request (BRR) requesting a transmission time slot, and receives a grant in response to the BRR. Subsequent to sending the BRR, a plurality of client data packets are accepted and concatenated into a bundled MoCA MAC frame. The bundled MoCA MAC frame is transmitted in a PHY packet in the granted time slot. | 01-08-2009 |
| 20100074624 | System and Method for Transporting Asynchronous ODUk Signals over a Synchronous Interface - System and methods are provided, in an Optical Transport Network (OTN), for communicating asynchronous Tributary Slots (TSs) via a synchronous Optical Payload Transport Unit of level k (OTUk) interface. The transmission method accepts a plurality of TSs at a corresponding plurality of asynchronous data rates. The TSs are mapped, using a tangible memory medium, into pseudo-Optical channel Data Tributary Unit (ODTU) frames synchronized to a common clock. Then, the synchronized pseudo-ODTU frames can be interleaved into an OTUk frame, without the need of a phase-locked loop (PLL) or buffering. | 03-25-2010 |
| 20100281343 | Virtual Lane Forward Error Correction in Multilane Distribution - A system and method are provided for generating virtual lane (VL) forward error correction (FEC) overhead (OH) in a communication multi-lane distribution (MLD) protocol transmitter, and for recovering data words from virtual lanes with FEC OH in an MLD protocol receiver. The transmission method accepts an Optical Transport Network (OTN) frame with n consecutively ordered payload chunks of data words, at a first data rate. Each payload chunk is assigned to a virtual lane data word (VLDW) in an MLD frame of n consecutively ordered VLDWs. The assignment order of payload chunks to VLDWs is rotated at the start of each MLD frame. VLDWs are joined into VLDW groups, where each VLDW group includes at least one VLDW. FEC blocks are calculated for VLDWs, creating ordered VL codewords (VLCWs). Then, the VLCWs are multiplexed to maintain a consistent assignment of VLCW order to physical transmission lanes and transmitted. | 11-04-2010 |
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| 20140037858 | ANISOTROPIC SURFACE ENERGY MODULATION BY ION IMPLANTATION - Methods of modulating a material's surface energies through the implantation of ions, such as by using a plasma processing apparatus with a plasma sheath modifier, are disclosed. Two or more ion implants may be performed, where the implant regions of two of the ion implants overlap. The species implanted by a first implant may increase the hydrophobicity of the surface, wherein the species implanted by the second implant may decrease the hydrophobicity of the surface. In this way, a workpiece can be implanted such that different portions of its surface have different surface energies. | 02-06-2014 |
| 20140242523 | Techniques For Patterning A Substrate - Various techniques for patterning a substrate are disclosed. Specifically, implantation of the first species into an anti-reflective coating layer is contemplated to reduce stress in the layer that may be generated during the exposure stage or development stage. During these steps, the resist layer or the resist structure may under mechanical changes (e.g. shrinkage) while it is in contact with the anti-reflective layer. Such changes may introduce stress in the anti-reflective layer, which may contribute to excessive line edge roughness (LER) or line width roughness (LWR). By implanting the first species before, during, or after these steps, the stress in the anti-reflective layer may be avoided or compensated, and excessive LER or LWR may be avoided or reduced. | 08-28-2014 |
| 20150325410 | APPARATUS AND METHOD FOR DYNAMIC CONTROL OF ION BEAM ENERGY AND ANGLE - In one embodiment a method of etching a substrate includes directing a first ion beam to the substrate through an extraction plate of a processing apparatus using a first set of control settings of the processing apparatus. The method may further include detecting a signal from the substrate that indicates a change in material being etched by the first ion beam from a first material to a second material, adjusting control settings of the processing apparatus to a second set of control settings different from the first set of control settings based on the second material, and directing a second ion beam to the substrate through the extraction plate using the second set of control settings. | 11-12-2015 |
| 20150355549 | ELECTRIC/MAGNETIC FIELD GUIDED ACID DIFFUSION - Methods and apparatuses for minimizing line edge/width roughness in lines formed by photolithography are provided. The random diffusion of acid generated by a photoacid generator during a lithography process contributes to line edge/width roughness. Methods disclosed herein apply an electric field and/or a magnetic field during photolithography processes. The field application controls the diffusion of the acids generated by the photoacid generator along the line and spacing direction, preventing the line edge/width roughness that results from random diffusion. Apparatuses for carrying out the aforementioned methods are also disclosed herein. | 12-10-2015 |
| 20160005594 | HIGH EFFICIENCY APPARATUS AND METHOD FOR DEPOSITING A LAYER ON A THREE DIMENSIONAL STRUCTURE - In one embodiment, a processing apparatus may include a process chamber configured to house a substrate and a hybrid source assembly that includes a gas channel coupled to a molecular source; and a plasma chamber configured to generate a plasma and isolated from the gas channel. The processing apparatus may also include an extraction assembly disposed between the hybrid source assembly and process chamber, coupled to the gas channel and plasma chamber, and configured to direct an ion beam to a substrate, the ion beam comprising angled ions wherein the angled ions form a non-zero angle with respect to a perpendicular to a substrate plane; and configured to direct a molecular beam comprising molecular species received from the gas channel to the substrate. | 01-07-2016 |
| 20160005839 | METHOD AND APPARATUS FOR SELECTIVE DEPOSITION - Methods for forming fin structures with desired materials formed on different locations of the fin structure using a selective deposition process for fin field effect transistors (FinFETs) are provided. In one embodiment, a method of forming a structure with desired materials on a substrate includes depositing a first material on a substrate having a three-dimensional (3D) structure formed thereon while performing an implantation process to dope a first region of the 3D structure. The first material may be removed and a second material may be deposited on the 3D structure. The second material may selectively grow on a second region of the 3D structure. | 01-07-2016 |
| 20160042922 | TECHNIQUES AND APPARATUS FOR ANISOTROPIC METAL ETCHING - In one embodiment, a method for etching a copper layer disposed on a substrate includes directing reactive ions to the substrate when a mask that defines an exposed area and protected area is disposed on the copper layer, wherein an altered layer is generated in the exposed area comprising a chemically reactive material; and exposing the copper layer to a molecular species that is effective to react with the chemically reactive material so as to remove the altered layer. | 02-11-2016 |
| 20160042975 | TECHNIQUES AND APPARATUS FOR ANISOTROPIC METAL ETCHING - In one embodiment, a method for etching a metal layer on a substrate may include providing a hydrogen-containing gas and an impurity gas to a plasma chamber; generating a plasma from the hydrogen-containing gas and the impurity gas in the plasma chamber, the plasma comprising hydrogen-containing ions; providing gaseous species from the plasma chamber to the substrate, wherein the providing the gaseous species comprises directing an ion beam comprising the hydrogen-containing ions formed from the plasma through an extraction aperture of an extraction plate disposed between the substrate and the plasma. | 02-11-2016 |
| 20160060767 | Ion Implant Assisted Metal Etching - An improved method of etching a metal substrate is described. After a mask layer is applied to the metal substrate, an ion implantation process is performed which implants ions, such as oxygen ions, into the exposed regions of the metal substrate. This implantation creates regions of metal oxide, which may be more susceptible to etching. Afterwards, the exposed regions of metal oxide are subjected to an etching process. This process may be through vaporization or may be a wet etch process. In some embodiments, the etchant is selected so that the metal oxide binds with the etchant to form a volatile compound, which stays in the vapor or gaseous state. This may reduce the unwanted deposition of the metal to other surfaces. These ion implantation and etching processes may be repeated a plurality of times to create a recessed feature of the desired depth. | 03-03-2016 |
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| 20110211518 | ADAPTIVE WIRELESS NETWORK - Systems, methods, and devices are provided for an adaptive wireless network. A wireless network device for an adaptive wireless network can include an application specific integrated circuit (ASIC) including logic and memory resources coupled to the ASIC. The logic can store information received from a number of clients associated with the wireless network device regarding capabilities of the number of clients in the memory resources. The logic can adapt a guard interval and/or a channel width for transmission of a data stream according to capabilities of a number of clients associated with the wireless network device. | 09-01-2011 |
| 20110216660 | SYNCHRONIZATION IN A WIRELESS NODE - A wireless node receives a beacon from a wireless access point. The beacon includes a wireless protocol time synchronization function (TSF) timestamp generated with reference to a global clock for a network. The wireless node synchronizes a counter according to the TSF timestamp. The wireless node receives a global timing offset (GTO) packet from the wireless access point and combines the GTO packet with a counter value to generate a global timestamp. | 09-08-2011 |
| 20120127970 | Wireless Network System And Method Configured To Mitigate Co-channel Interference - One embodiment provides a wireless network system ( | 05-24-2012 |
| 20120243520 | LOCATION-BASED ASSOCIATION FOR COMMUNICATIONS NETWORKS - In one implementation, a region descriptor associated with a communications access point and a location descriptor are accessed at a client. The client determines that a location described by the location descriptor is included within a region described by the region descriptor. The client then requests association with the communications access point in response to the determining. | 09-27-2012 |
| 20140286321 | METHOD OF ASSOCIATING A CLIENT WITH AN ACCESS POINT IN A WIRELESS LOCAL AREA NETWORK - A method of associating a client with an access point in a wireless local area network. The access point broadcasts a beacon announcing the existence of the access point. The beacon comprises a field which has a list of client identifiers of acceptable clients from which the access point will accept an association request. | 09-25-2014 |
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| 20100267150 | HDM2 POLYPEPTIDES - The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors. | 10-21-2010 |
| 20120208844 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF - The present invention provides a compound of Formula (1) as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same. | 08-16-2012 |
| 20140315916 | MACROCYCLES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF - The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same. | 10-23-2014 |
| 20140323482 | SUBSTITUTED PIPERIDINES AS HDM2 INHIBITORS - The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same. | 10-30-2014 |
| 20140336222 | SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF - The present invention provides a compound of Formula 1 | 11-13-2014 |
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| 20080202575 | METHODS FOR HIGH FIGURE-OF-MERIT IN NANOSTRUCTURED THERMOELECTRIC MATERIALS - Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured thermoelectric materials (e.g., modulation doping) are further disclosed. | 08-28-2008 |
| 20150068574 | METHODS FOR HIGH FIGURE-OF-MERIT IN NANOSTRUCTURED THERMOELECTRIC MATERIALS - Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured theromoelectric materials (e.g., modulation doping) are further disclosed. | 03-12-2015 |
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| 20090118437 | Interlayers Comprising Glycerol Based Plasticizer - The present invention includes interlayers and multiple layer glazing panels comprising those interlayers, wherein the interlayers comprise poly(vinyl butyral) and a glycerol based plasticizer. The addition of the glycerol based plasticizer surprisingly results in a plasticized poly(vinyl butyral) layer that is suitable for use in a wide range of multiple layer glazing applications. | 05-07-2009 |
| 20130074931 | POLYMER INTERLAYERS COMPRISING EPOXIDIZED VEGETABLE OIL - An interlayer comprised of a thermoplastic resin, varying amounts of an epoxidized vegetable oil, and, optionally, a conventional plasticizer. The use of a thermoplastic resin, an epoxidized vegetable (plant) oil, and, optionally, a conventional plasticizer creates synergy allowing the flow of the interlayer to be increased without sacrificing other characteristics typically associated with an increased flow (e.g., increased blocking and creep, exudation, surface roughness formation, decreased mechanical strength, and decreased manufacturing capability). In this regard, the epoxidized vegetable oil acts as a flow improvement agent, resulting in a high-flow interlayer. As a result, a thinner interlayer can be utilized in forming multiple layer panels because the resulting thinner interlayer has improved flow properties. | 03-28-2013 |
| 20140275390 | HYDROGEN PEROXIDE AS A REACTIVE EXTRUSION ADDITIVE FOR POLY(VINYL BUTYRAL) - A poly(vinyl butyral) (PVB) resin formulation, a method of extruding PVB resins, and related materials and products that provide for PVB sheets with a selectable flow (or melt viscosity) by melt blending hydrogen peroxide (H | 09-18-2014 |
| 20150125656 | HIGH FLOW POLYMER INTERLAYERS FOR LAMINATED GLASS - An interlayer comprised of a high flow, low molecular weight thermoplastic resin, and at least one plasticizer is disclosed. The use of a high flow, low molecular weight thermoplastic resin, and a plasticizer creates synergy allowing the flow of the interlayer to be increased without sacrificing other characteristics typically associated with an increased flow (e.g., increased blocking, decreased mechanical strength, and decreased manufacturing capability). In this regard, the high flow, low molecular weight thermoplastic resin provides a flow improvement, resulting in a high flow interlayer. As a result, a thinner interlayer can be utilized in forming multiple layer panels because the resulting thinner interlayer has improved flow properties. | 05-07-2015 |
| 20160059521 | HIGH FLOW POLYMER INTERLAYERS FOR LAMINATED GLASS - An interlayer comprised of a high flow, low molecular weight thermoplastic resin, and at least one plasticizer is disclosed. The use of a high flow, low molecular weight thermoplastic resin, and a plasticizer creates synergy allowing the flow of the interlayer to be increased without sacrificing other characteristics typically associated with an increased flow (e.g., increased blocking, decreased mechanical strength, and decreased manufacturing capability). In this regard, the high flow, low molecular weight thermoplastic resin provides a flow improvement, resulting in a high flow interlayer. As a result, a thinner interlayer can be utilized in forming multiple layer panels because the resulting thinner interlayer has improved flow properties. | 03-03-2016 |
| Patent application number | Description | Published |
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| 20120156176 | THERMORESPONSIVE, BIODEGRADABLE, ELASTOMERIC MATERIAL AND USES THEREFOR - Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. | 06-21-2012 |
| 20140213517 | Thermoresponsive, Biodegradable, Elastomeric Material and Uses Therefor - Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. | 07-31-2014 |
