Longo, US
Anthony Longo, Boston, MA US
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20150201030 | SYSTEMS AND METHODS FOR PROVIDING GEOGRAPHICALLY DELINEATED CONTENT - Systems and methods are provided that provide geographically delineated content. In one implementation, a system comprises an interface configured to receive, from a user device, a user input identifying a geographic location, a location-based service including a distributed computer system having at least one processor in data communication with the interface, a delineation component executable by the at least one processor and configured to query at least one social media content provider and aggregate geographically delineated content generated by one or more user, the content being received from the at least one social media content provider responsive to the received user input, and a relation component executable by the at least one processor and configured to determine a heatmap visualization from the aggregated geographically delineated content. | 07-16-2015 |
Brett J. Longo, Valley Centter, CA US
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20140054343 | Mobile Device Mount and Method of Using - This application relates to a mobile device mount and method of using the mount. In some embodiments, a mobile electronic device mount includes: a base configured to secure a first mobile electronic device to a second item; a body configured to receive and retain the first mobile electronic device; and a connector configured to connect the base to the body, wherein the connector includes a rotational component that allows the base and body to move from up to 360 degrees relative to each other in a first plane and move at least 170 degrees relative to each other in a second plane. | 02-27-2014 |
Brian C. Longo, Danville, CA US
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20140330915 | System and method for controlling electronic communications - The approved email generation system described is capable of producing email communications between user and customer by using approved email templates and content that have been aligned with customer information regarding access to such content. Once the approved email has been generated, the content may be verified again for accuracy and validity before being delivered to the customer. When the customer accesses delivered content, the approved email generation system again verifies the content and allows the customer access to only the most current version of the content available. The system provides for control of the content of electronic communications to customers. | 11-06-2014 |
20150236996 | System and method for controlling electronic communications - The approved email generation system described is capable of producing email communications between user and customer by using approved email templates and content that have been aligned with customer information regarding access to such content. Once the approved email has been generated, the content may be verified again for accuracy and validity before being delivered to the customer. When the customer accesses delivered content, the approved email generation system again verifies the content and allows the customer access to only the most current version of the content available. The system provides for control of the content of electronic communications to customers. | 08-20-2015 |
Caterina Longo, Fairfax, VA US
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20120164749 | Smart Hydrogel Particles for Biomarker Harvesting - Capture particles for harvesting analytes from solution and methods for using them are described. The capture particles are made up of a polymeric matrix having pore size that allows for the analytes to enter the capture particles. The pore size of the capture particles are changeable upon application of a stimulus to the particles, allowing the pore size of the particles to be changed so that analytes of interest remain sequestered inside the particles. The polymeric matrix of the capture particles are made of co-polymeric materials having a structural monomer and an affinity monomer, the affinity monomer having properties that attract the analyte to the capture particle. The capture particles may be used to isolate and identify analytes present in a mixture. They may also be used to protect analytes which are typically subject to degradation upon harvesting and to concentrate low an analyte in low abundance in a fluid. | 06-28-2012 |
Curtis Longo, Alta Loma, CA US
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20080237908 | Vibration apparatus and methods of vibration - The present invention relates to apparatus and methods of vibration. In particular, the present invention relates to apparatus and methods of vibration for tooling in a structure, such as, for example, a fuselage. In one implementation, the tooling comprises at least two conductors that create a force to vibrate the media in the tooling, which improves the compaction of the media in the tooling and the extraction of the media from the tooling. Other implementations may be used for compaction and/or extraction of the media in the tooling. | 10-02-2008 |
Dan Longo, Kensington, MD US
Patent application number | Description | Published |
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20090068234 | Methods and compositions for the treatment and prevention of cancer - The instant invention provides compositions for the treatment of cancer. Specifically, the invention provides polypeptides and nucleic acid molecules comprising tumor-associated embryonic antigens, e.g., OFA-iLRP, and chemoattractant ligands, e.g., a proinflammatory chemokine such as MIP3α/CCL20 or β-defensin mDF2β. The invention further provides cancer vaccines and methods for treating subjects having, or at risk of developing, cancer. | 03-12-2009 |
20120328640 | METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF CANCER - The instant invention provides compositions for the treatment of cancer. Specifically, the invention provides polypeptides and nucleic acid molecules comprising tumor-associated embryonic antigens, e.g., OFA-iLRP, and chemoattractant ligands, e.g., a proinflammatory chemokine such as MIP3α/CCL20 or β-defensin mDF2β. The invention further provides cancer vaccines and methods for treating subjects having, or at risk of developing, cancer. | 12-27-2012 |
Dan L. Longo, Kensington, MD US
Patent application number | Description | Published |
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20110014204 | Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2 - The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed to prevent tumor development in subjects at risk for developing colorectal cancer (CRC). The present invention also relates to methods of identifying increased risk in developing CRC in a subject, including methods of assessing the efficacy of a chemotherapeutic regimen. Further, the present invention relates to methods for identifying anti-neoplastic agents. | 01-20-2011 |
20150309026 | METHODS OF SCREENING FOR CELL PROLIFERATION OR NEOPLASTIC DISORDERS - The invention relates to methods and compositions for identifying subjects having, or predisposed to having, a neoplastic or cell proliferation or neoplastic disorder. The methods are applicable to any type of tissue sample and can be conducted on otherwise normal tissue. | 10-29-2015 |
Deirdre S. Longo, Morro Bay, CA US
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20140149413 | MANAGING A CLASSIFICATION SYSTEM AND ASSOCIATED SELECTION MECHANISM - Generating a wizard includes receiving a scheme as an input source to form a received scheme, wherein the received scheme is a taxonomy, receiving a defined set of content files to form received content files, and loading the received content files and the received scheme. The received content files can be tagged using the received scheme. A wizard can be generated using the received scheme. The generated wizard is capable of use with an application utilizing the scheme, wherein a change in the received scheme is directly represented in the generated wizard. | 05-29-2014 |
Diane Longo, Foster City, CA US
Patent application number | Description | Published |
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20110262468 | Method for Monitoring Vaccine Response Using Single Cell Network Profiling - The present invention provides methods for determining safety and efficacy of a vaccine by monitoring cellular pathways prior to and after vaccine treatment using single cell network profiling | 10-27-2011 |
20130218474 | Benchmarks for Normal Cell Identification - Methods for determining a model that can characterize and distinguish normal cell from a diseased cell and methods for determining health or health-risk status of an individual based on a normal/health cell reference population of cells are described. | 08-22-2013 |
20140120122 | METHOD FOR MONITORING VACCINE RESPONSE USING SINGLE CELL NETWORK PROFILING - The present invention provides methods for determining safety and efficacy of a vaccine by monitoring cellular pathways prior to and after vaccine treatment using single cell network profiling | 05-01-2014 |
20140127716 | BENCHMARKS FOR NORMAL CELL IDENTIFICATION - Provided herein are methods, compositions, and kits for determining cell signaling profiles in normal cells and comparing the cell signaling profiles of normal cells to cell signaling profiles from a test sample. | 05-08-2014 |
Frank M. Longo, Menlo Park, CA US
Patent application number | Description | Published |
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20100267727 | PHARMACEUTICAL FORMULATIONS COMPRISING NEUROTROPHIN MIMETICS - Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75 | 10-21-2010 |
20110003819 | METHODS OF TREATING MULTIPLE SCLEROSIS USING NEUROTROPHIN MIMETICS - Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75 | 01-06-2011 |
20110230479 | NEUROTROPHIN MIMETICS AND USES THEREOF - The present application is related to compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders associated with p75 expression, such as degradation or dysfunction of cells expressing p75 in a mammal by administering an effective amount of such compounds. | 09-22-2011 |
20120004310 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. | 01-05-2012 |
20130005731 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS - The present invention includes crystalline forms of 2-amino-3-methyl-N-(2-morpholinoethyl)-pentanamide and crystalline forms of salts and/or solvates of 2-amino-3-methyl-N-(2-morpholinoethyl)-pentanamide. Furthermore, the present invention provides compositions comprising the crystalline forms and therapeutic use of the crystalline forms. | 01-03-2013 |
20140100224 | NEUROTROPHIN MIMETICS AND USES THEREOF - The present application is related to compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders associated with p75 expression, such as degradation or dysfunction of cells expressing p75 in a mammal by administering an effective amount of such compounds. | 04-10-2014 |
20140200277 | METHODS OF FACILITATING NEURAL CELL SURVIVAL USING NON-PEPTIDE AND PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. | 07-17-2014 |
20140296343 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. | 10-02-2014 |
20150111903 | PHARMACEUTICAL FORMULATIONS COMPRISING NEUROTROPHIN MIMETICS - Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75 | 04-23-2015 |
20160023990 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. | 01-28-2016 |
20160046559 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule, optionally optionally in combination with a TrkA and/or TrkC receptor molecule. | 02-18-2016 |
Frank N. Longo, East Northport, NY US
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20080219944 | Polymer based antifouling coating - A coating composition comprising (i) at least one resin powder and (ii) at least one component selected from the group consisting of a metal compound, biocide and fluoropolymers. In particular, one antifouling composition that can be used on underwater stationary structures that sit in highly fouling environments comprises polyethylene as a resin powder, and copper in the form of cuprous or cupric oxide. | 09-11-2008 |
George Longo, Corsicana, TX US
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20140109370 | ASSEMBLY EQUIPMENT LINE AND METHOD FOR WINDOWS - The technology disclosed herein generally relate to assembly equipment for window units. In one embodiment, a window unit assembly system is taught that has a frame component that is configured to support equipment for a window unit assembly line. A pane conveyor is supported by the frame component and is configured to move panes along the window unit assembly line. A spacer conveyor is supported by the same frame component as the pane conveyor and is configured to move spacer elements along the window unit assembly line. | 04-24-2014 |
Gina Michelle Longo, Durham, NC US
Patent application number | Description | Published |
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20160050882 | Pet Portable Articulated Walkway (PetPAW) - The Pet Portable Articulated Walkway (PetPAW) is a portable pet ramp with integral protective folding sides and locking handles. The PetPAW is designed to allow owners of large and/or infirm pets to assist their pets in moving between heights (as from the ground to a car or other such distance) safely. The PetPAW s integral sides provide visual and physical protection from falls or missteps by the animals, and improved handle locking and securing features provide increased user protection against injury to hands and fingers during use. | 02-25-2016 |
Jeffrey Longo, Jupiter, FL US
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20130019521 | Method and system for production of biodiesel utilizing ultrasonic shear mixing to reduce the amount of energy needed by 45 to 50% and eliminate the use of water - The instant invention describes a method and system for producing biodiesel which increases energy efficiency by reducing the overall amount of energy associated with producing the biodiesel. Unlike most systems which use a batch procedure, the instant method and system utilize a continuous flow sonification procedure which provides for reactions to take place in tubes as the biodiesel moves along through the process. The continuous flow sonification procedure is performed in two main stages, utilizing the steps of acid esterification, transesterification, and a waterless washing. | 01-24-2013 |
Jim Longo, Mill Valley, CA US
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20120331095 | INVENTORY DATA ACCESS LAYER - There is provided a method that includes (a) receiving a request for access to data, (b) identifying a data store that stores the data, and (c) communicating with the data store, by way of an electronic communication, to access the data. There is also provided a system that performs the method, and a storage medium that includes a program module for controlling a processor to perform the method. | 12-27-2012 |
John M. Longo, Houston, TX US
Patent application number | Description | Published |
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20090254283 | METHOD FOR PETROPHYSICAL EVALUATION OF SHALE GAS RESERVOIRS - A method for evaluating an earth formation from a well bore, that includes: collecting at least one of geochemical data, petrophysical data and geomechanical data from a wellbore; and identifying depositional facies of the earth surrounding the wellbore. A computer program product and a system are provided. | 10-08-2009 |
20100312479 | USE OF CHEMICALLY AND GEOLOGICALLY CONSISTENT CONSTRAINTS FOR OBTAINING ELEMENTAL CHEMISTRY DOWNHOLE - A method for estimating a lithotype of an earth formation, the method includes: obtaining at least two different energy spectra of radiation received from the earth formation using the logging tool, each energy spectrum having at least one of a natural gamma-ray spectrum, a fast neutron-induced inelastic spectrum, and a thermal neutron induced capture spectrum; establishing at least one geochemically-based constraint related to elemental spectral yields to be determined; determining the elemental spectral yields from the at least two different energy spectra by decomposing the at least two different energy spectra over weighted sum of monoelemental standards wherein at least one weight is constrained by the at least one geochemically-based constraint and each weight represents a proportion of one monoelemental standard; converting the elemental spectral yields to elemental concentrations; and using a classifier to receive the elemental concentrations as input and to provide a lithotype as output. | 12-09-2010 |
20140197324 | METHODS TO ENHANCE NUCLEAR SPECTROSCOPY ANALYSIS - Methods, systems and devices for estimating a parameter of interest from a gamma ray spectrum relating to a volume of matter using standard gamma ray spectra from reference samples, wherein there is at least one non-elemental characteristic that is different between the volume and at least one of the reference samples, wherein the non-elemental characteristic difference affects gamma ray interactions. Methods may include deconvolving a gamma ray spectrum obtained from the analysis volume into a plurality of elemental spectral yields, wherein deconvolution includes compensating for effects of the non-elemental characteristic difference. Methods may include using at least one compensation standard spectrum configured to compensate for the effects of the non-elemental characteristic of the at least one of the reference samples. | 07-17-2014 |
20150129754 | Measurement of Downhole Gamma Radiation by Reduction of Compton Scattering - Systems, methods and devices for evaluating an earth formation intersected by a borehole. The method includes using a first radiation responsive component to detect gamma rays having an energy below a threshold energy; using a second radiation responsive component configured to detect gamma rays that traverse the first radiation responsive component; generating a reduced-Compton gamma ray spectrum by generating an anticoincidence gamma ray spectrum indicative of the gamma rays detected by the first radiation responsive component and the gamma rays detected by the second radiation responsive component. The anticoincidence gamma ray spectrum represents those gamma rays of the gamma rays detected by the second radiation responsive component that are not detected in coincidence with the gamma rays detected by the first radiation responsive component. | 05-14-2015 |
Joseph A. Longo, Paradise Valley, AZ US
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20140195002 | PERCUTANEOUS OSSEOINTEGRATED IMPLANT ASSEMBLY FOR USE IN SUPPORTING AN EXO-PROSTHESIS - An implant assembly for a long bone is adapted to support an exo-prosthesis. The assembly includes a stem, a subdermal component and a percutaneous post. The stem has a proximal end that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end having a surface that is adapted to promote bone ingrowth. The subdermal component includes a proximal portion that is adapted for attachment to the distal end of the stem, and a fixation surface that is adapted to promote soft tissue fixation. The percutaneous post has a proximal end that is adapted to be attached to the subdermal component. | 07-10-2014 |
Joseph Cosimo Longo, Feed Hills, MA US
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20100282118 | Chemiluminescent impact activated projectile - The present invention relates to a non-pyrotechnic, self-illuminating projectile useful for marking, target illumination, or targeting adjustment which produces chemiluminescent light upon impact with an object. Because the production of light is delayed until impact, the projectile is not visualized until impact and the intensity of light upon impact is greater than light produced by projectiles that provide intermixing of light generating chemicals during flight. | 11-11-2010 |
Joseph Cosimo Longo, Feeding Hills, MA US
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20090103279 | Evacuation station with multiple lightstick activation - A chemiluminescent lightstick evacuation station consisting of a wall mountable fixture that stores a plurality of lightsticks that are accessed by opening the fixture cover. The fixture cover is opened by pivoting from a closed position to an open position wherein a lightstick restraint causes the activation of all stored lightsticks so as to facilitate their removal and use during an emergency. One lightstick may be retained in the device by use of restricted movement housing, and all lightsticks may be made to rotate outwardly for ease of access. | 04-23-2009 |
20090175024 | Chemiluminescent tactical illumination baton - A light stick for providing chemiluminescent light to provide general illumination of an otherwise darkened area. The device is thrown into position causing the chemiluminescent components to mix upon impact with a rigid object thereby generating chemiluminescent light after a predetermined delay. The device will provide illumination to an area of possible criminal activity and can be used tactically by law enforcement officials to help avoid danger to themselves and possibly others. | 07-09-2009 |
20100097778 | Emergency light station with mechanically activated radio frequency signaling - A signaling system for an emergency light station containing chemiluminescent light sticks. The light station includes a cover that generates mechanical energy upon opening that is then transformed into electrical power. The electrical power is then utilized to transmit a radio frequency signal to a remote location is alert an observer to the fact that the light station has been opened. The alert provides an immediate indication that an emergency is in progress or that the safety emergency light station is being vandalized. | 04-22-2010 |
20120020050 | Chemiluminescent grenade - The present invention discloses a non-pyrotechnic, light emitting projectile for marking and illuminating a target. The projectile generally contains a main body having frangible side walls, at least one frangible ampoule containing chemiluminescent reactant components, a substantially incompressible filler material positioned between the frangible side walls and ampoule, and a first and second end cap. The first end cap is designed to be traversable between a first position and a second position upon impact with an object, thus provides a force sufficient to rupture the frangible side walls and ampoules. Rupture of the ampoules causes intermixing of the chemiluminescent reactant components and formation of a chemiluminescent slurry. The second end cap provides sufficient energy transfer to the chemiluminescent slurry upon impact with a target to disperse the chemiluminescent slurry radially and outwardly with respect to the longitudinal axis of the main body. | 01-26-2012 |
Kenneth A. Longo, Ann Arbor, MI US
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20090074886 | GSK-3 INHIBITORS - This invention relates to methods of treating or preventing bone loss by administering to a human or animal subject pyrimidine and pyridine derivatives that inhibit the activity of glycogen synthase kinase 3 (GSK3), to pharmaceutical compositions containing the compounds, and to the use of the compounds and compositions alone or in combination with other pharmaceutically active agents. | 03-19-2009 |
Larry Longo, Sudbury, MA US
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20150120608 | INTERACTIVE MULTIDIMENSIONAL PORTFOLIO ANALYSIS - Financial portfolios are analyzed based on a number of statistics and presented as a visualization on a display. The visualization is changeable based on user inputs, including definition by the user of a analysis period and selection of specific statistical filters. The visualization responds to the inputs substantially in real-time. | 04-30-2015 |
Leonard P. Longo, Bridgeville, PA US
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20120306619 | FINGERPRINTING APPARATUS, SYSTEM, AND METHOD - An apparatus, system and method for surreptitious biometric acquisition are disclosed. In one embodiment, a sensor is configured to produce an electrical signal corresponding to a biometric signature of a subject. The sensor is configured to be surreptitiously mounted to a surface. Various sensors are disclosed as being operative with the surreptitious biometric acquisition apparatus. A vehicle with a surreptitiously mounted biometric acquisition apparatus is disclosed. A method for surreptitious identification of suspects is also disclosed. | 12-06-2012 |
Lorenzo Longo, Laguna Beach, CA US
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20120243587 | System and Method for Implementing a Single Chip Having a Multiple Sub-Layer PHY - A system and method are disclosed for supporting 10 Gigabit digital serial communications. Many of the functional components and sublayers of a 10 Gigabit digital serial communications transceiver module are integrated into a single IC chip using the same CMOS technology throughout the single chip. The single chip includes a PMD transmit/receive CMOS sublayer, a PMD PCS CMOS sublayer, a XGXS PCS CMOS sublayer, and a XAUI transmit/receive CMOS sublayer. The single chip supports both 10 Gigabit Ethernet operation and 10 Gigabit Fibre Channel operation. The single chip interfaces to a MAC, an optical PMD, and non-volatile memory. | 09-27-2012 |
20120306061 | Apparatus and Method for Grounding an IC Package Lid for EMI Reduction - Methods and apparatus for improved electromagnetic interference (EMI) shielding and thermal performance in integrated circuit (IC) packages are described. A die-up or die-down package includes a protective lid, a plurality of ground posts, an IC die, and a substrate. The substrate includes a plurality of ground planes. The IC die is mounted to the substrate. Plurality of ground posts is coupled to plurality of ground planes that surround IC die. Protective lid is coupled to plurality of ground posts. The plurality of ground posts and the protective lid from an enclosure structure that substantially encloses the IC die, and shields EMI from and radiating towards the IC die. The enclosure structure also dissipates heat generated by the IC die during operation. | 12-06-2012 |
20130279551 | SYSTEM AND METHOD FOR IMPLEMENTING A SINGLE CHIP HAVING A MULTIPLE SUB-LAYER PHY - A system and method are disclosed for supporting 10 Gigabit digital serial communications. Many of the functional components and sublayers of a 10 Gigabit digital serial communications transceiver module are integrated into a single IC chip using the same CMOS technology throughout the single chip. The single chip includes a PMD transmit/receive CMOS sublayer, a PMD PCS CMOS sublayer, a XGXS PCS CMOS sublayer, and a XAUI transmit/receive CMOS sublayer. The single chip supports both 10 Gigabit Ethernet operation and 10 Gigabit Fibre Channel operation. The single chip interfaces to a MAC, an optical PMD, and non-volatile memory. | 10-24-2013 |
20140153620 | USE OF MULTI-LEVEL MODULATION SIGNALING FOR SHORT REACH DATA COMMUNICATIONS - A short reach communication system includes a plurality of communication SERDES that communicate data over a short reach channel medium such as a backplane connection (e.g., PCB trace) between, for example, chips located on a common PCB. A multi-level modulated data signal is generated to transmit/receive data over the short reach channel medium. Multi-level modulated data signals, such as four-level PAM, reduce the data signal rate therefore reducing insertion loss, power, complexity of the circuits and required chip real estate. | 06-05-2014 |
20150146766 | USE OF MULTI-LEVEL MODULATION SIGNALING FOR SHORT REACH DATA COMMUNICATIONS - A short reach communication system includes a plurality of communication SERDES that communicate data over a short reach channel medium such as a backplane connection (e.g., PCB trace) between, for example, chips located on a common PCB. A multi-level modulated data signal is generated to transmit/receive data over the short reach channel medium. Multi-level modulated data signals, such as four-level PAM, reduce the data signal rate therefore reducing insertion loss, power, complexity of the circuits and required chip real estate. | 05-28-2015 |
Martin D. Longo, Petaluma, CA US
Patent application number | Description | Published |
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20110106920 | Mapping Network Addresses to Organizations - Network addresses (e.g., IP addresses) are considered candidates for association with organizational entities (organizations or various subgroups thereof), based on some evidence of a relationship between them. The candidate addresses are scored based on one or more factors that indicate a probability that the candidate address actually belongs to the organizational entity. The candidate addresses with sufficient scores are stored as actual associations between the candidate address and the organizational entity. | 05-05-2011 |
20130173791 | Mapping Network Addresses to Organizations - Network addresses (e.g., IP addresses) are considered candidates for association with organizational entities (organizations or various subgroups thereof), based on some evidence of a relationship between them. The candidate addresses are scored based on one or more factors that indicate a probability that the candidate address actually belongs to the organizational entity. The candidate addresses with sufficient scores are stored as actual associations between the candidate address and the organizational entity. | 07-04-2013 |
Mary Longo, Germantown, MD US
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20110108420 | METHODS FOR PRODUCTION OF PROTEINS - The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such as | 05-12-2011 |
20140097086 | METHODS FOR PRODUCTION OF PROTEINS - The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such that host cells comprising the gene construct produce the polypeptide as intracellular inclusion bodies thereby facilitating rapid isolation and purification of recombinant proteins. The invention further provides methods for producing protein molecular weight ladders for us in protein gel electrophoresis, as well as proteins and protein molecular weight ladders produced by these methods. | 04-10-2014 |
Michael Longo, Glenmoore, PA US
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20130190787 | IMPLANTABLE FLOW CONNECTOR - A method of implanting and securing an implantable flow connector in a body of a patient for providing communication of a first space within the body of the patient with a second space within the body of the patient. The method includes providing a flow connector having a lumen having a first orifice and a second orifice, inserting a retention device into the first space within the body, subsequently inserting the flow connector through an opening in the retention device so the second portion of the flow connector extends into the first space within the body and placing the second space within the body over the retention device. | 07-25-2013 |
20130197546 | IMPLANTABLE FLOW CONNECTOR - A system for coupling a first space within the body of a patient with a second space within the body of the patient including a flow connector insertable into the first and second spaces within the body, the flow connector having a conduit having a lumen having a first orifice at a first portion of the conduit and a second orifice at a second portion of the conduit, the conduit providing communication between the first and second spaces within the body. A retention device retains the conduit with respect to the first space within the body and is engageable with the first space within the body. | 08-01-2013 |
20150223817 | IMPLANTABLE FLOW CONNECTOR - A system for coupling a first space within the body of a patient with a second space within the body of the patient including a flow connector insertable into the first and second spaces within the body, the flow connector having a conduit having a lumen having a first orifice at a first portion of the conduit and a second orifice at a second portion of the conduit, the conduit providing communication between the first and second spaces within the body. A retention device retains the conduit with respect to the first space within the body and is engageable with the first space within the body. | 08-13-2015 |
Michael Longo, Whittier, CA US
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20150087023 | PROTEIN ISOLATION - A general method and strains of bacteria are described by means where the endogeneous DNAK protein or homolog of the DNAK protein is tagged with a recognizable amino acid sequence and that through this tag, DNAK may be efficiently removed, and as such, recombinant protein purification may be greatly improved both in yield and purity with simplified purification steps that remove the DNAK and reduced cost, waste accumulation and labor, and the isolated recombinant protein will significantly benefit research and therapeutics in its application. | 03-26-2015 |
Michael A. Longo, Glenmoore, PA US
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20120071965 | IMPLANTABLE GRAFT CONNECTOR - A connector for fluidically connecting a graft to a patient's natural vessel to enable fluid to flow through the graft into the vessel. The connector comprises a main conduit having opposing ends each configured to be implanted in the vessel; and a branch conduit having a first end integral with the main conduit and a second end connectable to the graft, wherein the branch conduit extends at angle from the main conduit at a point between the opposing ends of the main conduit. | 03-22-2012 |
Michael J. Longo, Sterling Heights, MI US
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20150123408 | PUSHBUTTON LATCH MECHANISM FOR A VEHICLE - A pushbutton latch mechanism includes a module housing having first, second and third housing walls defining respective housing openings. The mechanism may be employed in a glove box assembly in a vehicle. An actuator is positioned at least partially within the module housing and defines an actuator slot. The actuator includes an actuator arm configured to be slidable relative to the second housing opening. A pushbutton is operatively connected to the module housing and includes a button arm configured to be insertable into the actuator slot and the first housing opening. Depression of the pushbutton in a first direction causes a first angled surface of the button arm to engage with a second angled surface of the actuator arm, thereby translating the actuator arm and a latch arm in a second direction in order to move the latch mechanism to an unlatched position. | 05-07-2015 |
Mike Longo, Whittier, CA US
Patent application number | Description | Published |
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20160090400 | ANTIBODY LIKE PROTEIN - A general method and recombinant nucleic acid sequences, by means which the method selects a recombinant protein containing an FHA domain for binding a target molecule from a library proteins with a high-throughput method of creating protein variations within the FHA domain in non-conserved or non-structural sequences of the FHA scaffold, and the library may also be in the form of a phagemid or phage library wherein the ALP nucleic acid sequence is inserted into a vector capable of allowing the vector and expressed ALP protein from being virally packaged, and the recombinant nucleic acid sequences which are randomly mutated at varying non-conserved or non-structural FHA domain sequences. | 03-31-2016 |
Nancy Longo, Kensington, MD US
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20140342407 | NEUTRALIZING GP41 ANTIBODIES AND THEIR USE - Monoclonal neutralizing antibodies are disclosed that specifically bind to the HIV-1 gp41 membrane-proximal external region (MPER). Also disclosed are compositions including the disclosed antibodies that specifically bind gp41, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of HIV-1 in a biological sample, or detecting an HIV-1 infection or diagnosing AIDS in a subject. In additional, the broad neutralization breadth of the disclosed antibodies makes them ideal for treating a subject with an HIV infection. Thus, disclosed are methods of treating and/or preventing HIV infection. | 11-20-2014 |
Nathan B. Longo, Calais, VT US
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20100170481 | Fog carburetor - A conversion system for a gasoline engine based generator enables the use of heavier fuels. A vertically disposed vortex separation chamber includes an inlet proximate the bottom of the chamber and tangential to the longitudinal axis of the chamber for delivering to the chamber partially vaporized fuel in an air-fuel mixture from a carburetor associated with the engine. An outlet proximate the top of the chamber also tangential to the longitudinal axis of the chamber for delivering vaporized fuel from the chamber to the engine. An electric heater is in communication with the bottom of the chamber for heating the chamber wall to vaporize any fuel thereon so vaporized fuel is reintroduced in swirling air-fuel mixture in the chamber. A battery source charged by the generator provides power to the electric heater. A jacket is disposed about and spaced from the chamber wall creating an annulus between the jacket and the chamber wall. An inlet through the jacket is connected to receive exhaust gas from the engine and to deliver the exhaust gas into the annulus for heating the chamber. | 07-08-2010 |
Nicolas Michel Jacques Longo, Chicago, IL US
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20160061657 | Ultraviolet Monitoring Device - Monitoring a user's exposure to ultraviolet radiation, including determining the amount of radiation to which the user is exposed from different directions, respectively. | 03-03-2016 |
Paul Longo, Portland, OR US
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20130190702 | MEDICAL APPLICATOR DEVICE - Embodiments provide a medical device in the form of an applicator for applying a medical composition to a patient. The applicator includes a body, a tip, and a delivery mechanism. The body defines a storage chamber for the medical composition and has an opening for deploying the medical composition from the storage chamber. The tip covers the opening and has a closed state wherein the tip maintains the medical composition in the storage chamber and an open state wherein the medical composition can be deployed through the opening and the tip. | 07-25-2013 |
Peter Longo, Cambridge, MA US
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20150278199 | CREATING A CALENDAR EVENT USING CONTEXT - Methods and systems are provided for creating a calendar event using context. A natural language expression including at least one of words, terms, and phrases of text may be received at a calendar event creation module from an application. The calendar event creation module may identify one or more slots in the text of the natural language expression related to the calendar event using a first grammar module and a second grammar module. The one or more slots identified by the first grammar module and the second grammar module that indicate a calendar event may be compared to determine whether there is a match between the one or more identified slots. If a match is found, at least one calendar event using the one or more slots identified by the first grammar module and the second grammar module may be created. | 10-01-2015 |
Peter P. Longo, Hopewell Junction, NY US
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20090107964 | DEBRIS MINIMIZATION AND IMPROVED SPATIAL RESOLUTION IN PULSED LASER ABLATION OF MATERIALS - A method of minimizing the deposition of debris onto a sample being ablated. The method comprises: 1) reducing a laser pulse energy to approximately a threshold level for ablation; 2) focusing the energy using an immersion object lens having a final element and 3) ablating a region of the sample using a multitude of laser pulses, each pulse being sufficiently separated in time to reduce a concentration of ablation products in a gas phase. | 04-30-2009 |
20100006550 | METHOD FOR MINIMIZING SAMPLE DAMAGE DURING THE ABLATION OF MATERIAL USING A FOCUSED ULTRASHORT PULSED LASER BEAM WHEREIN THE SLOPE OF FLUENCE BREAKDOWN IS A FUNCTION OF THE PULSE WIDTH - In one aspect the invention provides a method for laser induced breakdown of a material with a pulsed laser beam where the material is characterized by a relationship of fluence breakdown threshold (Fth) versus laser beam pulse width (T) that exhibits an abrupt, rapid, and distinct change or at least a clearly detectable and distinct change in slope at a predetermined laser pulse width value. The method comprises generating a beam of laser pulses in which each pulse has a pulse width equal to or less than the predetermined laser pulse width value. The beam is focused above the surface of a material where laser induced breakdown is desired. The region of least confusion (minimum beam waist or average spot size) is above the surface of the material in which laser induced breakdown is desired since the intensity of the beam falls off in the forward direction, preferably the region of the beam at or within the surface is between the region of least confusion and sufficient to remove material and the minimum intensity necessary for laser induced breakdown of the material to be removed, most preferably the region of minimum intensity is disposed at the surface of the material to be removed. The beam may be used in combination with a mask in the beam path. The beam or mask may be moved in the x, y, and Z directions to produce desired features. The technique can produce features smaller than the spot size and Rayleigh range due to enhanced damage threshold accuracy in the short pulse regime. | 01-14-2010 |
20100289186 | ENHANCED QUALITY OF LASER ABLATION BY CONTROLLING LASER REPETITION RATE - A method of enhancing the quality of laser ablation by controlling the laser repetition rate during the ablation process, wherein the method enhances the quality of laser ablation of a photomask in order to improve the optical quality thereof. Also provided is a system employing the method of enhancing the quality of laser ablation. | 11-18-2010 |
20110110578 | Evaluation of Image Processing Algorithms - One exemplary aspect of this invention pertains to a method to evaluate an image processing algorithm. The method includes varying a parameter of a model of an imaging system and, for each variation of the parameter, calculating with a data processor a corresponding image of a sample; applying an image processing algorithm to the calculated corresponding images of the sample; and determining an ability of the image processing algorithm to detect the variation in the parameter. | 05-12-2011 |
20130211388 | Apparatus for Minimizing Sample Damage During the Ablation of Biological Tissue Using a Focused Ultrashort Pulsed Laser Beam Wherein the Slope of Fluence Breakdown is a Function of the Pulse Width - An apparatus for laser induced breakdown of a tissue. The apparatus has a source of a beam of one or more laser pulses in which each pulse has a pulse width equal to or less than a pulse width value corresponding to a change in slope of a curve of fluence breakdown threshold (Fth) as a function of laser pulse width (T), the change occurring at a point between first and second portions of the curve, the first portion spanning a range of relatively long pulse width where Fth varies with the square root of pulse width (T1/2) and the second portion spanning a range of short pulse width relative to the first portion with Fth versus T slope which differs from that of the first portion; and an optical system focusing the one or more pulses of the beam to a point above the surface of the tissue to cause laser induced break down of the tissue. | 08-15-2013 |
20150265351 | Laser Surgical Apparatus and Methods of its Use Minimizing Damage During the Ablation of Tissue Using a Focused Ultrashort Pulsed Laser Beam Wherein the Slope of Fluence Breakdown is a Function of the Pulse Width - A laser apparatus for use in a surgical procedure including a housing forming a part of a handpiece and including interior and exterior regions. A laser cavity extending within the interior region of the housing. A cooling arrangement generating a stream of a first coolant. A precooling unit containing a second concentrated coolant. The cooling arrangement communicates with the precooling unit, so that a cooling stream having thermal calorific capacity higher than the thermal calorific capacity of the first coolant enters the laser cavity. The apparatus has a source of a beam of one or more laser pulses in which each pulse has a pulse width equal to or less than a pulse width value corresponding to a change in slope of a curve of fluence breakdown threshold (Fth) as a function of laser pulse width (T), the change occurring at a point between first and second portions of the curve, the first portion spanning a range of relatively long pulse width where Fth varies with the square root of pulse width (T½) and the second portion spanning a range of short pulse width relative to the first portion with Fth versus T slope which differs from that of the first portion; and an optical system focusing the one or more pulses of the beam to a point above the surface of the tissue to cause laser induced break down of the tissue. | 09-24-2015 |
Richard V. Longo, North Kingstown, RI US
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20110295283 | SOFT TISSUE REPAIR PROSTHESIS, EXPANDABLE DEVICE, AND METHOD OF SOFT TISSUE REPAIR - A hernia repair device is provided which may include a soft tissue repair prosthesis and an expandable device configured to be removably connected with the soft tissue repair prosthesis. When expanded, the expandable device may be configured to position the soft tissue repair prosthesis adjacent a hernia defect. The soft tissue repair prosthesis may include at least one loop or slit configured to receive a portion of the expandable device. The prosthesis may include a tether to hoist, locate or position the soft tissue repair prosthesis. The expandable device may include indicia for positioning the prosthesis relative to the edge of the hernia defect. | 12-01-2011 |
Sheila A. Longo, Somerville, MA US
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20080276408 | AUTONOMOUS COVERAGE ROBOT - A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface. | 11-13-2008 |
20080281470 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 11-13-2008 |
20120265343 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 10-18-2012 |
20120265346 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 10-18-2012 |
20140215735 | AUTONOMOUS COVERAGE ROBOT - A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface. | 08-07-2014 |
Sheila A. Longo, Seattle, WA US
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20130229356 | Fabric Enclosure Backlighting - Fabric enclosure backlighting techniques are described. In one or more implementations, one or more translucent portions are formed within a plurality of layers of a fabric enclosure assembly. In one approach, regions within one or multiple layers are laser etched to form the translucent portions within the fabric enclosure assembly. A light source is then arranged to selectively transmit light through the layers via the translucent portions to provide backlight for one or more elements integrated with fabric enclosure assembly. The one or more elements may include representations of input keys and/or graphics associated with the fabric enclosure assembly. The backlight may be used to view the one or more elements in low light and/or provide backlight effects such as borders, side lighting, labels, and so forth. | 09-05-2013 |
Stephen Longo, Northport, NY US
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20100326370 | Dog leash assembly - A leash assembly designed to attach at least one waste holding device, such as a plastic bag, in such a manner that the plastic bag is able to swivel about and not get tangled as the dog moves from side to side. This eliminates the need of the person walking the dog to constantly move the leash from one hand to the other hand in order to prevent the waste bag from getting tangled. In other words, as the dog move in different directions the waste bag holding device is able to adjust its' position by swiveling about the device attached to the leash allowing the walker to have their hands free. The swivel can also be adapted to hold other items such as keys, extra bags for dog cleanup and hand wipes. All of these items would also be able to swivel about the device. The present invention eliminates the need for the person walking the dog from carrying the waste bag and switching the bag from hand to hand as the dog moves from side to side until a waste receptacle is reached that the waste can be disposed of properly. | 12-30-2010 |
Stephen A. Longo, Dripping Springs, TX US
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20100153300 | DERIVATIVE TRADING STRATEGY BACKTESTING MACHINE - An automated information search, retrieval and reporting system, and more particularly, a system designed for the historical backtesting of financial market positions, for example, the simulation of the execution of derivative trading strategies. A user accesses data in a market information database via user interface by submitting queries in a near natural language format that define a desired derivative trading strategy with respect to one or more tradable securities. Historical daily price information about securities and derivatives are gathered and combined in a single location. Derivative relative data is created from the historical information and stored as a continuous historical series, wherein the derivative relative data is derived from each derivative's relative position to the underlying instrument with respect to price and date information. Reports express the results of the simulated execution of the derivative trading strategy that would have resulted from actual execution of the derivative trading strategy in the historical timeframe, including the daily profits and losses. | 06-17-2010 |
Thomas J. Longo, Redmond, WA US
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20150281413 | Input Device Attachment - Input device attachment techniques are described. In one or more implementations, an input device includes an input portion configured to generate signals to be processed by a computing device and a mid-spine that is physically attached to the input portion and configured to form a removable physical coupling to be secured to a first side of the computing device that includes a display device. The input device also includes a connection portion that is physically attached the mid-spine and is configured to form a removable physical coupling to be secured to a second side of the computing device that is different than the first side and form a communicative coupling to the computing device to communicate the generated signals from the input portion. | 10-01-2015 |
Tony Longo, Laguna Niguel, CA US
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20150225044 | SURF FIN INCLUDING INJECTION MOLDED PRE-IMPREGNATED COMPOSITE FIBER MATRIX INSERTS - A fin for a water sports board including leading and trailing edges, and a base extending therebetween along a longitudinal base axis. A fin axis extends generally perpendicular to the longitudinal base axis, both axes residing within a longitudinal plane. First and second opposed side faces are formed on generally opposed sides of the longitudinal plane. First and second insert pre-preg sheets formed of structural strands bonded by a resin material are disposed adjacent respective ones of the first and second side faces on generally opposed sides of the longitudinal plane. An injection molded resin material is disposed between the first and second insert pre-preg sheets. A core is positioned between the first and second insert pre-preg sheets and is of a density less than the injection molded resin material. | 08-13-2015 |
20150291265 | INJECTION MOLDED SURFBOARD INSERT HAVING PRE-IMPREGNATED COMPOSITE FIBER MATRIX STRUCTURE - An insert for a water sports board, wherein the insert includes a pre-preg flange extending outwardly from an injection molded central housing to provide enhance structural properties of the insert, as well as enhanced intermediate bonding between the injection molded central housing and a surface polymer. The pre-preg flange further improves the strength to weight ratio when compared to conventional inserts. | 10-15-2015 |
20150336641 | THERMOPLASTIC FIBER COMPOSITE WATER SPORTS BOARD AND FIN AND METHOD OF FORMING THE SAME - A structure, such as a fin or water sports board, including a core having opposed first and second core outer surfaces. The structure further includes first and second fiber sheets, wherein the first fiber sheet extends along the first core outer surface and the second fiber sheet extends along the second core outer surface. A thermoplastic material impregnates the first fiber sheet and the second fiber sheet and bonds the first fiber sheet and the second fiber sheet to the core. The thermoplastic material defines an outer surface of the structure. | 11-26-2015 |
Valter Longo, Playa Del Rey, CA US
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20080242638 | INDUCTION OF DIFFERENTIAL STRESS RESISTANCE AND USES THEREOF - This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. | 10-02-2008 |
20120329712 | Induction of Differential Stress Resistance and Uses Thereof - This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. | 12-27-2012 |
20140328863 | Induction of Differential Stress Resistance and Uses Thereof - This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. | 11-06-2014 |
20150133370 | Dietary Compositions and Methods for Protection Against Chemotherapy, Radiotherapy, Oxidative Stress, and Aging - The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging. | 05-14-2015 |
Valter Longo, Los Angeles, CA US
Patent application number | Description | Published |
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20100004309 | Dietary Compositions and Methods for Protection Against Chemotherapy, Radiotherapy, Oxidative Stress, and Aging - The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging. | 01-07-2010 |
Valter D. Longo, Playa Del Rey, CA US
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20110118528 | Methods and Nutritional Formulations to Increase the Efficacy and Reduce the Side Effects of Cancer Treatment - The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides nutritional methods and formulations that are capable of reducing cancer growth without causing chronic weight loss in patients, protecting normal cells, tissues and organs from chemotherapy and/radiation therapy, and sensitizing cancer cells against low, normal and high-dose chemotherapy. Some of the methods also impede cancer growth even without chemotherapy. | 05-19-2011 |
20130045215 | GROWTH HORMONE RECEPTOR DEFICIENCY CAUSES A MAJOR REDUCTION IN PRO-AGING SIGNALING, CANCER AND DIABETES IN HUMANS - A method for alleviating a symptom of chemotherapy in a subject comprises identifying a subject undergoing chemotherapy and then administering a therapeutically effective amount of a GH/IGF-1 Axis inhibitory composition to the subject. Typically, the levels of IGF-1 and/or GH in the subject are monitored as well as chemotherapy related symptoms. A method of alleviating oxidative damage, cellular damage including mutations, and insulin resistance in a subject is also provided. | 02-21-2013 |
20130316948 | GROWTH HORMONE RECEPTOR DEFICIENCY CAUSES A MAJOR REDUCTION IN PRO-AGING SIGNALING, CANCER AND DIABETES IN HUMANS - A method for alleviating a symptom of chemotherapy in a subject comprises identifying a subject undergoing chemotherapy and then administering a therapeutically effective amount of a GH/IGF-1 Axis inhibitory composition to the subject. Typically, the levels of IGF-1 and/or GH in the subject are monitored as well as chemotherapy related symptoms. A method of alleviating oxidative damage, cellular damage including mutations, and insulin resistance in a subject is also provided. | 11-28-2013 |
20140112909 | METHODS AND FORMULATIONS PROMOTING TISSUE/ORGAN REGENERATION, LONGEVITY AND HEALTHSPAN - A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day. | 04-24-2014 |
20150250771 | USE OF SHORT TERM STARVATION REGIMEN IN COMBINATION WITH KINASE INHIBITORS TO ENHANCE TRADITIONAL CHEMO-DRUG EFFICACY AND FEASIBILITY AND REVERSE SIDE EFFECTS OF KINASES IN NORMAL CELLS AND TISSUES - A method of alleviating or treating symptoms of cancer and/or effects of chemotherapy or of kinase inhibitors includes a step of identifying a subject having cancer. A reduced caloric diet is administered to the subject for a first time period, the reduced caloric diet providing at most 1000 kcal per day. A kinase inhibitor is administered to the subject. | 09-10-2015 |
Vince Longo, Huntington Beach, CA US
Patent application number | Description | Published |
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20150225044 | SURF FIN INCLUDING INJECTION MOLDED PRE-IMPREGNATED COMPOSITE FIBER MATRIX INSERTS - A fin for a water sports board including leading and trailing edges, and a base extending therebetween along a longitudinal base axis. A fin axis extends generally perpendicular to the longitudinal base axis, both axes residing within a longitudinal plane. First and second opposed side faces are formed on generally opposed sides of the longitudinal plane. First and second insert pre-preg sheets formed of structural strands bonded by a resin material are disposed adjacent respective ones of the first and second side faces on generally opposed sides of the longitudinal plane. An injection molded resin material is disposed between the first and second insert pre-preg sheets. A core is positioned between the first and second insert pre-preg sheets and is of a density less than the injection molded resin material. | 08-13-2015 |
20150291265 | INJECTION MOLDED SURFBOARD INSERT HAVING PRE-IMPREGNATED COMPOSITE FIBER MATRIX STRUCTURE - An insert for a water sports board, wherein the insert includes a pre-preg flange extending outwardly from an injection molded central housing to provide enhance structural properties of the insert, as well as enhanced intermediate bonding between the injection molded central housing and a surface polymer. The pre-preg flange further improves the strength to weight ratio when compared to conventional inserts. | 10-15-2015 |
20150336641 | THERMOPLASTIC FIBER COMPOSITE WATER SPORTS BOARD AND FIN AND METHOD OF FORMING THE SAME - A structure, such as a fin or water sports board, including a core having opposed first and second core outer surfaces. The structure further includes first and second fiber sheets, wherein the first fiber sheet extends along the first core outer surface and the second fiber sheet extends along the second core outer surface. A thermoplastic material impregnates the first fiber sheet and the second fiber sheet and bonds the first fiber sheet and the second fiber sheet to the core. The thermoplastic material defines an outer surface of the structure. | 11-26-2015 |
William Longo, Mentor, OH US
Patent application number | Description | Published |
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20110209424 | SELF ADHERING WINDOW FLASHING TAPE WITH MULTI-DIRECTIONAL DRAINAGE PLANE - The disclosure provides a self adhesive, flexible tape for flashing exterior wall openings. The tape is a composite comprising a barrier layer having an exterior surface and an interior surface and an adhesive layer overlying the interior surface. The barrier layer exterior surface is patterned to provide a gravity drainage path in both the tape machine direction (MD) and tape cross machine direction (CD). | 09-01-2011 |