Livingston, US
Alexander Livingston, Eagle, ID US
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20090252994 | BATTERY PACK SYSTEM - The invention described here is a modular energy system for electric vehicles. This modular electrical power system is comprised of a group of battery packs, a rack, and a charging and exchange station. Each battery pack fits into a case that has a handle to make it easy to grasp and lift from its holder. Battery packs are limited to no more than thirty pounds each. The battery packs are installed in a rack which is secured to the vehicle. The rack has defined positions or slots in which the battery packs are placed. The battery pack includes heat sinks to remove the heat from the batteries. The charging and exchange station allows the user two options; 1) recharge the vehicle while parked without removing the batteries, or 2) exchange the vehicles batteries for fully charged packs. | 10-08-2009 |
Andy Livingston, Cape Neddick, ME US
Andy Livingston, Portsmouth, NH US
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20100200191 | GEOTHERMAL HEATING AND COOLING SYSTEM AND METHOD - A method of providing a geothermal heating and cooling system for a building having the steps of designing and installing a geothermal heat pump and loop field system to a customer's building; calculating a periodic fee to be charged to the customer; measuring the actual geothermal system usage; and charging the customer the periodic fee which is comprised of a base fee and a usage charge based on the amount the system is in operation. | 08-12-2010 |
Boyd Thomas Livingston, Columbia, MD US
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20120004111 | DIRECT IDENTIFICATION AND MEASUREMENT OF RELATIVE POPULATIONS OF MICROORGANISMS WITH DIRECT DNA SEQUENCING AND PROBABILISTIC METHODS - The present invention relates to systems and methods capable of characterizing populations of organisms within a sample. The characterization may utilize probabilistic matching of short strings of sequencing information to identify genomes from a reference genomic database to which the short strings belong. The characterization may include identification of the microbial community of the sample to the species and/or sub-species and/or strain level with their relative concentrations or abundance. In addition, the system and methods may enable rapid identification of organisms including both pathogens and commensals in clinical samples, and the identification may be achieved by a comparison of many (e.g., hundreds to millions) metagenomic fragments, which have been captured from a sample and sequenced, to many (e.g., millions or billions) of archived sequence information of genomes (i.e., reference genomic databases). | 01-05-2012 |
20140136120 | DIRECT IDENTIFICATION AND MEASUREMENT OF RELATIVE POPULATIONS OF MICROORGANISMS WITH DIRECT DNA SEQUENCING AND PROBABILISTIC METHODS - The present invention relates to systems and methods capable of characterizing populations of organisms within a sample. The characterization may utilize probabilistic matching of short strings of sequencing information to identify genomes from a reference genomic database to which the short strings belong. The characterization may include identification of the microbial community of the sample to the species and/or sub-species and/or strain level with their relative concentrations or abundance. In addition, the system and methods may enable rapid identification of organisms including both pathogens and commensals in clinical samples, and the identification may be achieved by a comparison of many (e.g., hundreds to millions) metagenomic fragments, which have been captured from a sample and sequenced, to many (e.g., millions or billions) of archived sequence information of genomes (i.e., reference genomic databases). | 05-15-2014 |
20140288844 | CHARACTERIZATION OF BIOLOGICAL MATERIAL IN A SAMPLE OR ISOLATE USING UNASSEMBLED SEQUENCE INFORMATION, PROBABILISTIC METHODS AND TRAIT-SPECIFIC DATABASE CATALOGS - The present invention relates to systems and methods for the characterization of biological material within a sample or isolate. The characterization may utilize probabilistic methods that compare sequencing information from fragment reads to sequencing information of reference genomic databases and/or trait-specific database catalogs. The characterization may be of the identities and/or relative concentrations or abundance of one or more organisms contained in the sample or isolate. The identification of the organisms may be to the species and/or sub-species and/or strain level with their relative concentrations or abundance. The characterization may additionally or alternatively be of one or more traits (i.e., characteristics) of the biological material contained in the sample or isolate. The characterization of the one or more traits may be with the relative abundance of the traits. | 09-25-2014 |
Brandon L. Livingston, Mason, OH US
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20110144437 | METHODS AND DEVICES FOR PROVIDING SURGICAL ACCESS THROUGH TISSUE TO A SURGICAL SITE - Methods and devices are provided for providing surgical access into a body cavity. A surgical access port is provided that has an adjustable longitudinal length, such as by being formed from multiple segments configured to move relative to one another. An anchor can be coupled to a distal end of the surgical access port to help secure the surgical access port within a tissue opening by engaging a distal side of the tissue. Optionally, the anchor can be removably coupled to the distal end of the surgical access port, thereby allowing any one of a plurality of anchors to be selectively coupled thereto. | 06-16-2011 |
20110144449 | METHODS AND DEVICES FOR PROVIDING ACCESS THROUGH TISSUE TO A SURGICAL SITE - Methods and devices are provided for providing access through tissue to a surgical site. Generally, the methods and devices allow adjustment of a surgical access port's longitudinal length. In one embodiment, a surgical access port is provided that includes a housing having a cannula distally extending therefrom. The housing can be configured to cut a proximal portion of the cannula to adjust a longitudinal length of the cannula and hence of the surgical access port. In another embodiment, a surgical access port is provided that includes a cannula formed of a plurality of modular segments removably coupled together. One or more of the segments can be configured to be removable from the cannula to change the cannula's longitudinal length. | 06-16-2011 |
20110144589 | INVERTED CONICAL EXPANDABLE RETRACTOR - Access devices and related methods are disclosed that generally involve flexible or adjustable cannulas that have a substantially cylindrical insertion configuration and a substantially conical expanded configuration. Various methods and features are provided for transitioning the cannula from the insertion configuration to the expanded configuration while the access device is inserted through tissue to form a conical opening through the tissue. Examples include cables, biasing elements, retaining elements, bimodal rings, and coil springs. The devices and methods disclosed herein can allow for improved retention of the access device, improved angulation of instruments passed through the access device, and can increase the integrity of a seal formed between the access device and surrounding tissue. | 06-16-2011 |
Craig Livingston, Canistota, SD US
Darren D. Livingston, Denver, CO US
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20090179032 | Method and Apparatus for Providing A Positive Pressure in the Headspace of a Plastic Container - The present invention is directed to a method and apparatus for accommodating the pressure decrease of the fluid in a hot-filled plastic container. | 07-16-2009 |
20110131933 | PRESSURIZED CAPPING APPARATUS - Apparatus for pressurizing the headspace of a filled plastic bottle while applying a cap includes a sealing ring having a surface for engaging a support ring, or other surface of known dimension, of the plastic bottle, clamping apparatus for moving the sealing ring, a chuck for holding the cap in a position to engage a finish of the plastic bottle, a pressure chamber surrounding the chuck having a sealing surface for contacting the sealing ring, a source of pressure coupled to the pressure chamber for introducing a volume of gas or vapor at super-atmospheric pressure into the chamber, and a motor for rotating the chuck and cap within the pressure chamber while the chamber is subjected to the gas or vapor at super-atmospheric pressure to seal the gas or vapor within the headspace of the filled plastic bottle with the cap. | 06-09-2011 |
David Livingston, Barrington, RI US
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20090023157 | Proteome epitope tags and methods of use thereof in protein modification analysis - Disclosed are methods for reliably detecting the presence of proteins, especially proteins with various post-translational modifications (phosphorylation, glycosylation, methylation, acetylation, etc.) in a sample by the use of one or more capture agents that recognize and interact with recognition sequences uniquely characteristic of a set of proteins (Proteome Epitope Tags, or PETs) in the sample. Arrays comprising these capture agents or PETs are also provided. | 01-22-2009 |
David J. Livingston, Newtonville, MA US
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20110015371 | Inhibitors of interleukin-1 beta converting enzyme - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against interleukin-1 mediated diseases, including inflammatory diseases, autoimmune diseases and neurodegenerative diseases. This invention also relates to methods for inhibiting ICE activity and methods for treating interleukin-1 mediated diseases using the compounds and compositions of this invention. | 01-20-2011 |
20110178069 | INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-γ-mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-γ-mediated diseases and decreasing IGIF and IFN-γ production using the compounds and compositions of this invention. This invention also relates to methods for preparing N-acylamino compounds. | 07-21-2011 |
20120165319 | INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-γ-mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-γ-mediated diseases and decreasing IGIF and IFN-γ production using the compounds and compositions of this invention. This invention also relates to methods for preparing N-acylamino compounds. | 06-28-2012 |
20120238749 | INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against interleukin-1 mediated diseases, including inflammatory diseases, autoimmune diseases and neurodegenerative diseases. This invention also relates to methods for inhibiting ICE activity and methods for treating interleukin-1 mediated diseases using the compounds and compositions of this invention. | 09-20-2012 |
David J. Livingston, Barrington, RI US
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20100159446 | Detection Assays and Use Thereof - The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system. | 06-24-2010 |
20100159455 | RECEPTOR FAMILY PROFILING - The invention provides compositions and methods, e.g., assay technologies and their use in biodetection and diagnostics. More particularly, the invention provides compositions and methods based on nucleic acid-templated chemistry in biodetection and profiling of receptors (and their families) and proteins (and their families), and the use of same in diagnostics. | 06-24-2010 |
20110059458 | COMPOSITIONS AND METHODS FOR CATALYZING DNA-PROGRAMMED CHEMISTRY - The present invention relates compositions and methods that are useful in catalyzing DNA-Programmed Chemistry (or Nucleic Acid-templated chemistry) for use in therapeutic and diagnostic applications. | 03-10-2011 |
David M. Livingston, Brookline, MA US
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20080286199 | Methods of Detecting Ovarian Cancer - The present invention provides methods of detecting ovarian cancer using biomarkers. | 11-20-2008 |
20090185977 | Composition and method for imaging cells - The invention relates to compositions containing a polynucleotide encoding for a reporter gene, a selectable marker and a regulatory element, that provide a method for imaging cells in vivo. | 07-23-2009 |
David W. Livingston, Claremore, OK US
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20100096161 | Downhole Cable With Thermally Conductive Polymer Composites - A cable for transmitting electricity for use with an electric submersible pump has a plurality of conductors for conducting electricity along the length of the cable. A first layer of insulation surrounds each of the conductors. A jacket, or second layer of insulation, surrounds all of the conductors and the first layer of insulation. Both the first layer of insulation and the jacket insulation are comprised of an polymeric compound. At least one of the insulation layers has filler material dispersed therein, the filler material having a higher level of thermal conductivity than the insulation layer it is contained in. | 04-22-2010 |
20120063931 | Electrical Submersible Pump System Having High Temperature Insulation Materials - Electric submersible well pumping systems operable in well temperatures of above about 180° C. (356° F.) utilize high temperature electrical insulation. The electrical insulation includes E-base polyimide films or perfluoropolymer TE films on various components. The insulation films are employed around magnet wires that are threaded through slots in the stator. Slot insulation of E-base polyimide or perfluoropolymer TE film surrounds the magnet wires in the stator slots. Sheets of E-base polyimide or perfluoropolymer TE film extend around and between phase loops of the magnet wire at the lower end of the stator. The motor contains a PAO oil having additives to dissipate acid generated by epoxy used in the motor. | 03-15-2012 |
20120063934 | Electrical Submersible Pump System Having High Temperature Slot, End Bell and Phase-to-Phase Insulation - Electric submersible well pumping systems operable in well temperatures of above about 180° C. (356° F.) utilize high temperature electrical insulation. The electrical insulation includes E-base polyimide films or perfluoropolymer TE films on various components. The insulation films are employed around magnet wires that are threaded through slots in the stator. Slot insulation of E-base polyimide or perfluoropolymer TE film surrounds the magnet wires in the stator slots. Sheets of E-base polyimide or perfluoropolymer TE film extend around and between phase loops of the magnet wire at the lower end of the stator. The motor contains a PAO oil having additives to dissipate acid generated by epoxy used in the motor. | 03-15-2012 |
David W. Livingston, Julian, PA US
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20080274887 | SOLID MOSS CONTROL COMPOSITION - A method of controlling moss by applying to grass infested with moss a dry composition including: a) a source of nitrogen such as isobutylenediurea or methylene urea; b) a non-ionic surfactant or wetting agent; c) a metal containing salt, and d) an acidic pH adjusting agent effective to adjust the pH of the composition to a pH of between 2.5 and 5 when wetted on grass. The dry composition may be a granular composition, and may be applied by broadcasting over a large area. | 11-06-2008 |
20120309624 | Solid Moss Control Composition - A method of controlling moss by applying to grass infested with moss a dry composition including: a) a source of nitrogen such as isobutylenediurea or methylene urea; b) a non-ionic surfactant or wetting agent; c) a metal containing salt, and d) an acidic pH adjusting agent effective to adjust the pH of the composition to a pH of between 2.5 and 5 when wetted on grass. The dry composition may be a granular composition, and may be applied by broadcasting over a large area. | 12-06-2012 |
Donald Livingston, East Dorset, VT US
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20120166241 | SYSTEMS AND METHODS FOR RFID SUPPLY CHAIN MANAGEMENT - According to various embodiments, a supply chain management system may provide dynamic information regarding items in manufacturing, storage, inventory, or retail processes by detecting RFID tags embedded on the items. A supply chain management system may also be configured to determine current inventory and regulate what items are stocked and restocked on displays. A split-screen showing detected items and instructions or information pertaining to the items may facilitate accurate and efficient execution of process steps by an employee or user. Supply chain management systems may also provide for re-tagging items with lost or damaged RFID tags and finding items lost from inventory due to lost or damaged RFID tags. Furthermore, a supply chain management system may include RFID tags affixed to point of purchase displays and include information regarding the point of purchase display within a database. | 06-28-2012 |
Dwight Livingston, Fallston, MD US
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20080251489 | Pierceable cap - A pierceable cap may be used for containing sample specimens during storage and transport. The pierceable cap may prevent unwanted escape of sample specimen before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the pierceable cap may allow passage of a tip of a transfer device though the pierceable cap. A frangible layer may be disposed across the access port. One or more extensions proximate to the frangible layer may be coupled to the pierceable cap by coupling regions or other similar devices. The one or more extension may rotate around the one or more coupling regions during insertion of the transfer device. The movement of the one or more extensions may pierce the frangible layer to create airways and allow air to escape from a vessel at a reduced velocity. | 10-16-2008 |
20080251490 | Pierceable cap - A pierceable cap maybe used for containing sample specimens during storage and transport. The pierceable cap may prevent unwanted escape of sample specimen before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the pierceable cap may allow passage of a tip of a transfer device though the pierceable cap. Multiple frangible layers maybe disposed across the access port. One or more extensions proximate to a lower frangible layer may rotate around one or more coupling regions during insertion of the transfer device. The movement of the one or more extensions may pierce the lower frangible layer to create airways and allow air to escape from a vessel at a reduced velocity. Upper frangible layers may prevent escape of materials from spaces intermediate between the lower frangible layer and the upper frangible layers. | 10-16-2008 |
20140206088 | UNITIZED REAGENT STRIP - The embodiments disclosed herein relate to unitized reagent strips for holding and transporting reagents and materials used in automated sample preparation and/or processing for biological and or chemical assays. | 07-24-2014 |
Frederick Livingston, Raleigh, NC US
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20090234262 | Health Monitoring and Management System - A health monitoring and management device, system, and/or method can include a sensor adapted to detect changes in one or more health indicators and transmit data related to the health indicators. The system can further include an interventional element adapted to receive a health intervention command and provide a health intervention related to the health indicators. The system can further include a microprocessor adapted to receive and analyze the health indicator data transmitted by the sensor, formulate the health intervention command related to the health indicator data according to pre-determined parameters, and transmit the health intervention command to the interventional element. The health intervention command can be transmitted to the interventional element within a clinically relevant time period. | 09-17-2009 |
20090234265 | Compression Adjustable Fabric and Garments - A compression adjustable fabric and/or garment, system, and/or method can include a compression element (a) integrated into a fabric structure, (b) having a compressive pressure capability independent from compressive pressure capabilities inherent in the fabric structure, and (c) adjustable to provide various compressive pressures. In such a garment, the compressive pressure provided by the garment can be adjusted in all or part of the garment while the garment is being worn. The compressive pressures in different parts of the garment may be independently adjustable. The compression element can further comprise an inflatable tube and/or an electrically stimulatable yarn. The compression element can be integrated into the fabric structure by being knit into, or laid in, the fabric structure. | 09-17-2009 |
Gary Livingston, Bloomfield, IA US
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20120194343 | DRIVING AID - A driver alert system to assist a driver in remaining alert comprising: a cooling element; a sleeve, where said sleeve receives and holds the cooling element; a plurality of body attachments, where said body attachments extend from the sleeve and may be attached to the driver's skin in order to transfer a cooling sensation to the driver's skin; a power cord, where said power cord supplies power to the sleeve. The sleeve may include an extension for the power cord that may be plugged into the DC power outlet of a vehicle such as a cigarette lighter. In one particular embodiment, the plurality of body attachments include: a Velcro strap, where the strap wraps around a driver's arm or wrist; and a headphone, where the headphone includes cooling templates that may be placed upon the driver's head. | 08-02-2012 |
Ian Livingston, Chandler, AZ US
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20130026545 | MULTIPLE WELL DRAIN ENGINEERING FOR HV MOS DEVICES - At least one N-well implant having a different doping level is formed in a silicon substrate by first etching the substrate with an alignment target for aligning future process masks thereto. This alignment target is outside of any active device area. By using at least one N-well implant having a different doping level in combination with the substrate, a graded junction in the drift area of a metal oxide semiconductor (MOS) field effect transistor (FET) can be created and a pseudo Ldd structure may be realized thereby. | 01-31-2013 |
Jacqueline C. Livingston, Washington, OH US
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20100064942 | Corundum Crystal Structure Pigments With Reduced Soluble Chromium Content - The potential for release of soluble chromium (VI) ions in the production or processing of certain pigments is reduced by use of certain additives. The additives include aluminum metaphosphate, aluminum fluoride, tungsten oxide, tungstic acid, and mono-ammonium phosphate. The pigments are those which contain chromium and have a corundum crystal structure. | 03-18-2010 |
James N. Livingston, Guilford, CT US
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20090047687 | Indane Acetic Acid Derivatives and Their Use as Pharmaceutical Agents, Intermediates, and Method of Preparation - This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation. | 02-19-2009 |
20110065129 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION - This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation. | 03-17-2011 |
20110152330 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION - This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation. | 06-23-2011 |
20110152331 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION - This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation. | 06-23-2011 |
Jamie Livingston, Simpsonville, SC US
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20100143146 | FLATBACK INSERT FOR TURBINE BLADES - A blade for the use in the generation of power has a leading edge and a trailing edge. A first shell portion of the blade extends from the leading edge to the trailing edge. A second shell portion of the blade also extends from the leading edge to the trailing edge. A root portion of the blade is positioned proximate the wind turbine and a tip portion which extends from the root portion away from the wind turbine. A trailing edge insert is positioned between the first shell portion and the second shell portion proximate the root portion. The trailing edge insert has a surface which extends between and separates the first shell portion from the second shell portion at the trailing edge, such that the insert provides a high lift profile for increased blade efficiency. | 06-10-2010 |
20110142666 | NOISE REDUCER FOR ROTOR BLADE IN WIND TURBINE - A rotor blade assembly for a wind turbine is disclosed. The rotor blade assembly includes a rotor blade having surfaces defining a pressure side, a suction side, a leading edge, and a trailing edge extending between a tip and a root. The rotor blade further includes a noise reducer configured on a surface of the rotor blade, the noise reducer comprising a plurality of serrations, each of the plurality of serrations defining a centerline. The centerline of each of the plurality of serrations defines a individual tailored angle dependent on at least one of span-wise location, local chord, width, length, bend angle, and thickness | 06-16-2011 |
20110206529 | SPAR ASSEMBLY FOR A WIND TURBINE ROTOR BLADE - A spar assembly for a rotor blade of a wind turbine is disclosed. The spar assembly may generally include a first spar cap and a second spar cap spaced apart from the first spar cap such that a cross-sectional area is defined directly between the first and second spar caps. Additionally, the spar assembly may include a web having a first end disposed adjacent to the first spar cap and a second end disposed adjacent to the second spar cap. The web may be configured such that at least a portion of an inner surface of the web is disposed outside of the cross-sectional area. | 08-25-2011 |
20120141277 | Integrated Lightning Receptor System and Trailing Edge Noise Reducer for a Wind Turbine Rotor Blade - A rotor blade assembly for a wind turbine includes a rotor blade having a pressure side member, a suction side member, a leading edge, and a trailing edge extending between a tip and a root. An electrically conductive band extends longitudinally on either or both of the pressure side member and suction side member along the trailing edge. A plurality of electrically conductive noise reduction features extend from the trailing edge and are configured as individual lightning strike receptors. The noise reduction features are configured in conductive communication with the conductive band. | 06-07-2012 |
Jamie Thomas Livingston, Simpsonville, SC US
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20090162206 | MULTI-SEGMENT WIND TURBINE BLADE AND METHOD FOR ASSEMBLING THE SAME - A multi segment wind turbine blade comprises at least two blade segments. A first blade segment comprises an outer skin, a bulkhead, and first alignment brackets removably coupled to the outer skin of the first blade segment. A first portion of a flange of the bulkhead is bonded to the first blade segment and a second portion of the flange of the bulkhead projects out from the first blade segment. A second blade segment comprises an outer skin and second alignment brackets removably coupled to the outer skin of the first blade segment. The first and second alignment brackets are alignable upon the outer side of the second blade segment being inserted over the second portion of the flange of the bulkhead. | 06-25-2009 |
20090162208 | MULTI-SEGMENT WIND TURBINE BLADE AND METHOD FOR ASSEMBLING THE SAME - A multi-segment wind turbine blade comprises at least two blade segments. A first spar cap segment is attached to a first blade segment and a second spar cap segment is attached to a second blade segment. The first and second spar cap segments are configured to form a scarf joint. First and second spar cap brackets are attached in locations of the first and second spar cap segments, respectively, selected to facilitate alignment of the first and second spar cap segments at the scarf joint. At a field site, the first and second spar cap segments are bonded after fastening the first and second spar cap brackets. | 06-25-2009 |
20100321012 | DRIVE COIL, MEASUREMENT PROBE COMPRISING THE DRIVE COIL AND METHODS UTILIZING THE MEASUREMENT PROBE - The invention provides a drive coil and measurement probe comprising the drive coil. The measurement probes can be used, for example, in in-situ, non-destructive testing methods, also provided herein. | 12-23-2010 |
20120087801 | COMPOSITE COMPONENTS AND PROCESSES THEREFOR - Composite components fabricated to have shapes with in-plane curvature, for example, a spar cap for an airfoil having a swept configuration. A process for fabricating the component includes forming prepregs to have a laminate architecture containing a fibrous reinforcement material in a matrix of a partially-cured polymer material. The prepregs are stacked and bonded together to form a straight elongate preform. An in-plane curvature is then induced in the preform within a plane containing longitudinal and transverse directions of the preform so as to create a swept configuration. The in-plane curvature is induced by applying forces parallel to the transverse direction of the preform while the preform is at a temperature of less than the melting temperature of the polymer material, such that the polymer material cold flows. The polymer material is then fully cured to yield the composite component. | 04-12-2012 |
20140169978 | ROTOR BLADE ASSEMBLIES AND METHODS FOR ASSEMBLING THE SAME - Methods of assembling rotor blades include providing a first blade segment comprising a first shell portion and at least two first spar cap segments and providing a second blade segment comprising a second shell portion and at least two second spar cap segments. An access region is defined in at least one of the first shell portion and the second shell portion. The second blade segment is then inserted into the first blade segment, such that a spar cap cavity is formed between each set of corresponding first and second spar cap segments, and wherein an access window is defined by the access region at an interface between the first blade segment and the second blade segment, the access window providing access to the spar cap cavities. The method further includes sealing the spar cap cavities and injecting an adhesive into the spar cap cavities to bond the blade segments together, wherein a scarf joint is formed between each set of corresponding first and second spar cap segments. | 06-19-2014 |
20140178204 | WIND TURBINE ROTOR BLADES WITH FIBER REINFORCED PORTIONS AND METHODS FOR MAKING THE SAME - Methods of manufacturing a fiber reinforced portion of a wind turbine rotor blade include disposing a continuous fiber mat adjacent a prefabricated layer, wherein the continuous fiber mat comprises randomly arranged reinforcing fibers and wherein the prefabricated layer comprises reinforcing fibers and a cured polymeric resin. The method further includes disposing a structural layer adjacent the continuous fiber mat opposite the prefabricated layer, wherein the structural layer comprises reinforcing fibers. The method then includes infusing a polymeric resin through at least the continuous fiber mat and curing the resin to form the fiber reinforced portion of the wind turbine rotor blade. | 06-26-2014 |
Jane Livingston, Tonka Bay, MN US
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20090091909 | Vertical cable management system with ribcage structure - A cable management system is provided including a rack for holding telecommunications equipment, and a ribcage cable support member along a vertical side of the rack. The ribcage cable support member includes a plurality of forwardly and rearwardly extending ribs. The ribs each include cable retention tabs. A plurality of spools are provided for cable storage on the ribcage cable support member. Holes through the ribcage cable support member allow access between the front and rear portions. An additional rack may be positioned on an opposite side of the ribcage cable support member to the first rack, and two columns of ribs are provided. | 04-09-2009 |
20100315800 | Vertical cable management system with ribcage structure - A cable management system is provided including a rack for holding telecommunications equipment, and a ribcage cable support member along a vertical side of the rack. The ribcage cable support member includes a plurality of forwardly and rearwardly extending ribs. The ribs each include cable retention tabs. A plurality of spools are provided for cable storage on the ribcage cable support member. Holes through the ribcage cable support member allow access between the front and rear portions. An additional rack may be positioned on an opposite side of the ribcage cable support member to the first rack, and two columns of ribs are provided. | 12-16-2010 |
Jason Livingston, Somerville, MA US
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20140085620 | 3D PRINTER WITH SELF-LEVELING PLATFORM - 3D printing systems and methods avoid build-compromising misalignments through the use of a self-leveling assembly that maintains a constant and typically fully parallel orientation between a build platform and the bottom surface of a resin tank. As a result, contact between the floor of the resin tank and the build platform surface may be uniformly flat and even, and perpendicular to the z-axis motion of the deposition source. | 03-27-2014 |
Jason C. Livingston, Scotch Plains, NJ US
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20090248056 | APPLICATOR INSTRUMENTS FOR CONTROLLING BLEEDING AT SURGICAL SITES AND METHODS THEREFOR - An instrument for controlling bleeding includes an outer shaft having a central lumen extending between proximal and distal ends thereof, and an inner shaft disposed within the central lumen of the outer shaft, the inner shaft having a central lumen extending between proximal and distal ends thereof. The instrument has an inflatable balloon with a proximal end secured to the outer shaft and a distal end that is inverted and secured to the inner shaft. In one embodiment, the balloon has a spherical shape when the outer and inner shafts are in a first position and a toroidal shape when the outer and inner shafts are in a second position. The instrument includes an actuator for discharging a flowable material from the central lumen. In one embodiment, the instrument includes a stylet having barb-like features to attach a hemostat to the distal end of the instrument. | 10-01-2009 |
John M. Livingston, Ayer, MA US
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20090129398 | STACKABLE ROUTERS EMPLOYING A ROUTING PROTOCOL - A stack of network routers is composed of at least one (elected) master unit and one or more slave units each capable of running a routing protocol. Only the master unit runs the entire routing protocol at a given time. It forwards direct update messages via a transmission control protocol to each of the slave units. These direct update messages may include specific packet formats for the protocol state machinery where such machinery is required by the routing protocol, e.g., the interface state machine and the neighbor state machine for the OSPF protocol, and for the net databases, e.g. the link state databases for the OSPF protocol, in each of the slave units. Each slave unit may run its protocol state machinery (where provided) based purely on the direct update messages received from the master. The synchronisation of the net databases may be based on snooping net update packets and a comparison of the information received thereby with verification data messages sent from the master unit. The synchronization allows the running of the routing protocol on multiple physical routers in a stack without requiring the overhead of a back-up unit that would not perform routing unless a master router unit became unavailable. | 05-21-2009 |
Joseph Livingston, Camillus, NY US
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20100012717 | CUSTOMIZABLE OPTICAL READER - An optical reader, which is operable in a “host commands” mode and a “host routines” mode. In the “host commands” mode, the reader receives and executes a script routine module from a host. In the “host routines” mode, the reader receives a script routine Module identifier from the host, and the reader, in turn, executes a selected one of a plurality of reader-stored script routine modules based on the identifier. | 01-21-2010 |
20110233280 | TERMINAL WITH RADIO TRANSCEIVER HAVING POWER OUTPUT - There is provided for herein a terminal having a radio transceiver, the radio transceiver having a maximum output power and an operating power. The operating power is limitable to a power limit that less than or equal to the maximum output power and is operator selectable from a set of power limit values so as to reduce interference with other devices operating in the 2.4 GHz spectrum of the ISM band. In one embodiment, the set of power limit values includes the maximum output power and a plurality of additional values. In another embodiment, the set of power limit values includes a plurality of values, the plurality of values including at least first and second values less than 16 dB apart in magnitude. | 09-29-2011 |
Karla Naomi Livingston, Las Vegas, NV US
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20120234788 | Bottle Device - An apparatus and method for delivery of expressed breast milk to be ingested by a newborn. This is achieved by placing the fully assembled apparatus around the caregiver's neck which allows the apparatus to hang at the chest area of the caregiver and provides the newborn with direct access to the expressed milk through the apparatus. This apparatus replicates the breastfeeding and bonding process between the newborn and the caregiver, be it male or female. This is achieved by adding expressed breast milk into a conical, recycled glass container; attaching the nipple and nipple cap assembly; placing the recycled rubber cover over the glass container holding it in place with the two recycled rubber tabs at the bottom of the recycled rubber cover and delivering the expressed milk to the infant in any upright breastfeeding position. | 09-20-2012 |
Kelly Livingston, Elkton, MD US
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20140115596 | CODELETSET REPRESENTATION, MANIPULATOIN, AND EXECUTION - METHOD, SYSTEM AND APPARATUS - Codeletset methods and/or apparatus may be used to enable resource-efficient computing. Such methods may involve decomposing a program into sets of codelets that may be allocated among multiple computing elements, which may enable parallelism and efficient use of the multiple computing elements. Allocation may be based, for example, on efficiencies with respect to data dependencies and/or communications among codelets. | 04-24-2014 |
Ken D. Livingston, Collinsville, OK US
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20130097837 | Single Brake Spring Tool and Method of Removal of Drum Brake Spring - A brake drum spring release tool includes a straight elongate rod member with a laterally projecting lever arm extending from one side and an extended hook member from the end of the rod member. The lever arm acts as a fulcrum when positioned on a drum brake spring simultaneously engaged by a hook member. Placing a generally lateral force on the grip end of the tool will cause rotational force imparted by the hook member on the spring typically with a mechanical advantage associated with the fulcrum of the lever arm to thereby release the spring from a drum brake shoe. | 04-25-2013 |
Kenneth Livingston US
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20090114198 | Ultrasonic fuel/power enhancer - An ultrasonic fuel/power enhancer for producing sound and ultrasound at different wind speeds and conditions is provided. The enhancer is mountable in an air intake of a vehicle with the vehicle having a predetermined number of cylinders and each cylinder having a combustion chamber. The enhancer comprises at least one band and at least one tubular whistle. A whistle connection mechanism is wrapped around the whistle with the whistle connection mechanism having at least one band receiving aperture and the band insertable through one of the band receiving apertures. At least one stabilizing tab is mounted to the whistle connection mechanism wherein the whistle is shaped and designed to produce sonic and ultrasonic sounds thereby atomizing gas droplets being supplied to the combustion chamber of each cylinder. | 05-07-2009 |
Lynda Livingston, Williamsport, PA US
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20090038068 | Spa cover - A spa cover includes an internal heat insulation material having an outer covering which is impermeable to water and water vapor. It absorbs very little water significantly increasing the life of the spa cover. The outer cover is created from a poly halogenated vinyl polymer designed to significantly decrease pore size and water vapor permeability. The outer cover is also laminated from several layers of the poly halogenated vinyl polymer each having a ‘grain’. The grains are angularly offset to further reduce water vapor permeability. | 02-12-2009 |
20090313751 | Thermal Spa Cover - A thermal spa cover assembly [ | 12-24-2009 |
Mark A. Livingston, Alexandria, VA US
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20090244082 | METHODS AND SYSTEMS OF COMPARING FACE MODELS FOR RECOGNITION - Methods and systems of representation and manipulation of surfaces with perceptual geometric features, using a computer graphics rendering system, include executing algorithmic instructions to compute a plurality of vertices, edges and surfaces in a mesh for the purpose of defining representations of surfaces on grids. Normals and distances are determined for triangular surfaces to be considered. Additionally, height fields of a function are defined. A set of feature curves and a set of feature points are derived, based on the defined function. Infinitesimal movements along the representations of the surfaces are determined, along with derivations of properties of representations of continuous surfaces. Additional determinations of perceptual geometric features include determinations such as zero crossings, parabolic curves, flecnodes, ruffles, gutterpoints, conical points and biflecnodes in a given mesh. After these determinations are made, visual representation are rendered which captures perceptually important features for smoothly varying shapes. | 10-01-2009 |
Mark Alan Livingston, Alexandria, VA US
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20100042563 | SYSTEMS AND METHODS OF DISCOVERING MIXTURES OF MODELS WITHIN DATA AND PROBABILISTIC CLASSIFICATION OF DATA ACCORDING TO THE MODEL MIXTURE - Discovering mixtures of models includes: initiating learning algorithms, determining, data sets including a cluster of points in a first region of a domain and a set of points distributed near a first line extending across the domain; inferencing parameters from the cluster and the set of points; creating a description of the cluster of points in the first region of the domain and computing approximations of a first learned mixture model and a second learned mixture model; determining a first and second probability, generating a confidence rating that each point of the cluster of points in the first region of the domain corresponds to the first learned mixture model and generating a confidence rating that each point of the set of points distributed near the first line correspond to the second learned mixture model, thus causing determinations of behavior of a system described by the learned mixture models. | 02-18-2010 |
20130039575 | SYSTEM AND METHOD OF IMAGE PROCESSING PERCEPTUAL VISIBILITY OF IMAGERY - An image processing system and method corrects the perceptual quality of an image by adjusting the image colors. “Color” in this sense is to be understood as encompassing three-dimensional parameterizations of color, incorporating both intensity and hue. These measurements are made using creative computations developed and adapted from the RETINEX™ theory (Land, 1977), where the RETINEX implementation adjusts any pixel in any direction in color space and further to automatically determine the best direction for it to be adjusted to increase the perceptual visibility of the algorithm with a minimal amount of change to the original image values. | 02-14-2013 |
Michael D. Livingston, Germantown, MD US
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20090259700 | SYSTEM AND METHOD FOR LOGSTREAM ARCHIVAL - A method of archiving data from a logstream includes determining a begin time parameter earlier in time than a last record obtained from the logstream of data. A request is sent for records from the logstream of data starting at the begin time parameter. Records are received from the logstream of data and selected records are archived. | 10-15-2009 |
Michael Kent Livingston, Pine, CO US
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20130186322 | Reliable Deer Whistle - A deer whistle for vehicular safety is provided which is more reliable than known deer whistles. A single body had therethrough two whistle cavities, and the manufacture of the whistle is done in a manner, and using structures, which provide for accurate sound production. In particular, the device uses a raised weld between the whistle portions, alignment posts and recesses to further increase the accuracy of manufacture, and finally uses a specified combination of heat and pressure in whistle manufacture for the weld. | 07-25-2013 |
Michelle Livingston, Wolfeboro, NH US
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20110052453 | REMOVAL OF CARBON DIOXIDE FROM A FLUE GAS STREAM - A method and apparatus for removing carbon dioxide and other pollutants from a gas stream having components that work synergistically. The invention includes an ammonia based scrubbing solution for SO2 scrubbing; an SO2 absorption section ( | 03-03-2011 |
Patrick Livingston, Easton, PA US
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20100300716 | SWINGING WEIGHT ASSEMBLY FOR IMPACT TOOL - A swinging weight assembly for an impact tool includes an anvil having an impact jaw that is reinforced with a circumferential flange. A hammer includes a hammer lug and a cam lug for pivoting the hammer between an engaged position in which the hammer lug strikes the impact jaw and a disengaged position in which the hammer moves past the impact jaw. The cam lug is separated from the cam lug to define a space in which the reinforcing flange is received. | 12-02-2010 |
Patrick Sean Livingston, Easton, PA US
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20090194306 | POWER TOOL HOUSING SUPPORT STRUCTURES - A tool housing which in one aspect includes a body defining a head portion with a handle portion depending therefrom to define a forward and/or a rear junction. A metal reinforcing member is configured to span along an inside surface of the body from the head portion to the handle portion such that the reinforcing member bridges either the forward or rear junction. In another aspect, the tool assembly comprises a tool housing body, a motor positioned within the tool body housing, a drive mechanism connected with the motor to define a unitary motor/drive mechanism assembly, and at least one elastic isolating member extending about a portion of the motor/drive mechanism assembly such that the motor/drive mechanism assembly is elastically isolated relative to the housing body. | 08-06-2009 |
20150065018 | Grinders with Friction Drives - In one illustrative embodiment, a grinder may comprise an arbor configured to rotate about a first axis and to support a grinding wheel for rotation therewith, a gear surrounding a first portion of the arbor and having a slip fit with the first portion of arbor, a motor configured to drive rotation of a drive train including the gear, a collar surrounding a second portion of the arbor and having an interference fit with the second portion of the arbor such that the collar is constrained for rotation with the arbor about the first axis, and at least one spring disposed between the gear and the collar and configured to exert a biasing force along the first axis such that one or more resulting friction forces cause the arbor to rotate with the gear when a torque exerted on the gear is less than a threshold torque. | 03-05-2015 |
Philip Livingston, New York, NY US
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20110229510 | GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF - Glycopeptide conjugates, and methods of making and using such conjugates are disclosed. Certain glycopeptide conjugates comprise tumor associated carbohydrate antigens and peptide epitopes. Certain glycopeptide conjugates comprise cyclic peptide scaffolds that display carbohydrate antigens in a clustered fashion. The immunogenicity of select glycopeptide conjugates is demonstrated. | 09-22-2011 |
20110300177 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF - The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation. | 12-08-2011 |
20130011421 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF - The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation. | 01-10-2013 |
20150086585 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF - The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation. | 03-26-2015 |
Philip O. Livingston, New York, NY US
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20080241195 | Optimal Polyvalent Vaccine for Cancer - This invention provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of: a) selection of an appropriate cancer cell line; and b) detection of the expression of antigens on the surface of said cell line of the cancer, wherein the antigens expressed will be used in the polyvalent vaccine. This invention also provides a method for identification of the optimal combination of a polyvalent vaccine against a cancer comprising steps of : a) selection of an appropriate cancer cell line and b) detection of the immunogenicity will be used in the polyvalent vaccine. This invention provides various uses of the identified polyvalent vaccine. | 10-02-2008 |
20090060938 | Polyvalent Conjugate Vaccine for Cancer - This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Le | 03-05-2009 |
20110206757 | NOVEL GLYCOCONJUGATES, GLYCOAMINO ACIDS, INTERMEDIATES THERETO, AND USES THEREOF - The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein. | 08-25-2011 |
20120263749 | POLYVALENT CONJUGATE VACCINE FOR CANCER - This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Le | 10-18-2012 |
20130095173 | MULTIVALENT GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF - Glycopeptide conjugates comprising GM2 and/or Gb5 carbohydrate determinants, and methods of making and using such conjugates are disclosed. The immunogenicity of select glycopeptide conjugates is demonstrated. | 04-18-2013 |
20140037673 | POLYVALENT CONJUGATE VACCINE FOR CANCER - This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Le | 02-06-2014 |
20140271817 | NOVEL GLYCOCONJUGATES, GLYCOAMINO ACIDS, INTERMEDIATES THERETO, AND USES THEREOF - The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein. | 09-18-2014 |
Robert J. Livingston, Seattle, WA US
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20120058902 | METHOD OF MEASURING ADAPTIVE IMMUNITY - Compositions and methods for measuring adaptive immune receptor (T cell receptor and immunoglobulin) diversity are described, and find uses for assessing immunocompetence and other purposes. Means are provided for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it. Lymphoid (B- and T-cell) adaptive immune receptor diversity is quantified by calculating the number of uniquely rearranged, CDR3-containing immunoglobulin (Ig) or T-cell receptor (TCR) variable region-encoding genes from sample cells such as blood cells. | 03-08-2012 |
20130288237 | QUANTIFICATION OF ADAPTIVE IMMUNE CELL GENOMES IN A COMPLEX MIXTURE OF CELLS - Compositions and methods are described for highly sensitive quantification of the relative representation of DNA from adaptive immune cells (e.g., T and/or B lymphocytes) in DNA extracted from complex mixtures of cells that include cells which are not adaptive immune cells. Included are methods for determining the relative presence in a tumor of tumor infiltrating lymphocytes (TIL), the relative presence of lymphocytes infiltrating a somatic tissue that is the target of an autoimmune disease, and the relative presence of lymphocytes infiltrating a transplanted organ. | 10-31-2013 |
20140186848 | Quantification of Adaptive Immune Cell Genomes in a Complex Mixture of Cells - Compositions and methods are described for highly sensitive quantification of the relative representation of DNA from adaptive immune cells (e.g., T and/or B lymphocytes) in DNA extracted from complex mixtures of cells that include cells which are not adaptive immune cells. Included are methods for determining the relative presence in a tumor of tumor infiltrating lymphocytes (TIL), the relative presence of lymphocytes infiltrating a somatic tissue that is the target of an autoimmune disease, and the relative presence of lymphocytes infiltrating a transplanted organ. | 07-03-2014 |
20150017652 | Compositions and Method for Measuring and Calibrating Amplification Bias in Multiplexed PCR Reactions - Compositions and methods are described for standardizing the DNA amplification efficiencies of a highly heterogeneous set of oligonucleotide primers as may typically be used to amplify a heterogeneous set of DNA templates that contains rearranged lymphoid cell DNA encoding T cell receptors (TCR) or immunoglobulins (IG). The presently disclosed embodiments are useful to overcome undesirable bias in the utilization of a subset of amplification primers, which leads to imprecision in multiplexed high throughput sequencing of amplification products to quantify unique TCR or Ig encoding genomes in a sample. Provided is a composition comprising a diverse plurality of template oligonucleotides in substantially equimolar amounts, for use as a calibration standard for amplification primer sets. Also provided are methods for identifying and correcting biased primer efficiency during amplification. | 01-15-2015 |
20150051089 | Quantification of Adaptive Immune Cell Genomes in a Complex Mixture of Cells - Compositions and methods are described for highly sensitive quantification of the relative representation of DNA from adaptive immune cells (e.g., T and/or B lymphocytes) in DNA extracted from complex mixtures of cells that include cells which are not adaptive immune cells. Included are methods for determining the relative presence in a tumor of tumor infiltrating lymphocytes (TIL), the relative presence of lymphocytes infiltrating a somatic tissue that is the target of an autoimmune disease, and the relative presence of lymphocytes infiltrating a transplanted organ. | 02-19-2015 |
Rod Livingston, Richmond, IN US
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20080282565 | ECCENTRICITY GAUGE FOR WIRE AND CABLE AND METHOD FOR MEASURING CONCENTRICITY - A device for measuring the location of a conductor within an insulating sheath using three measuring planes, in which at least one measuring plane is able to locate the conductor and at least one is able to locate the periphery of the outer sheath. | 11-20-2008 |
20140208499 | Bagging Toilet - A waste receiving apparatus such as a toilet has a body having an interior and an upper waste receiving opening. A bagging material storage area holds the bag supply of continuous bag material to receive waste introduced through the waste receiving opening. A motor is provided for rotating accumulated waste relative to the bag supply. A fan is provided for pressurizing and/or depressurizing an interior of the body. | 07-31-2014 |
Samantha S. Livingston, Tueson, AZ US
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20090292755 | METHODS AND APPARATUS FOR SIGNATURE PREDICTION AND FEATURE LEVEL FUSION - A system for signature prediction and feature-level fusion of a target according to various aspects of the present invention includes a first sensing modality for providing a measured data set. The system further includes a processor receiving the measured data set and generating a first k-orthogonal spanning tree constructed from k orthogonal minimal spanning trees having no edge shared between the k minimal spanning trees to define a first data manifold. | 11-26-2009 |
Scott Livingston, Louisville, MS US
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20100302768 | RECESSED LUMINAIRE WITH A REFLECTOR - A HID recessed luminaire is disclosed and described. The HID recessed luminaire includes a reflector that has a primary reflector portion and a secondary reflector portion. The primary reflector portion defines a first frustum of a pyramid and the secondary reflector portion defines a second frustum of a pyramid. Optionally, a portion of the primary reflector and a portion of the secondary reflector are integrally connected to one another. | 12-02-2010 |
Scott M. Livingston, Towson, MD US
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20090120254 | Table Saw - The table saw disclosed herein includes a table, a saw assembly pivotally attached to the table, the saw assembly comprising an arbor movable relative to the table, a bevel shaft operatively connected to the saw assembly for pivoting the saw assembly, and a height shaft operatively connected to the saw assembly for moving the arbor relative to the table, wherein distance between the height shaft and the table is larger than distance between the bevel shaft and the table. Also disclosed is a saw includes a table having a first miter gauge slot, a base supporting the table, a saw assembly pivotably connected to at least one of the table and the base for carrying a rotatable cutting tool so that the tool protrudes through and above the table, at least part of the saw assembly being underneath the table, the saw assembly comprising a cradle, and a sector gear connected to the cradle, and a first bevel stop disposed underneath the first miter gauge slot, wherein the first bevel stop can contact the sector gear when the saw assembly is pivoted in one direction. | 05-14-2009 |
Sean L. Livingston, Bothell, WA US
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20090006884 | AUTOMATICALLY MANAGING SYSTEM DOWNTIME IN A COMPUTER NETWORK - Embodiments are provided to automatically managing system downtime in a computer network. In one embodiment, an event is created in an application server to schedule a system downtime period for a web server. When the scheduled downtime occurs, the web server is automatically removed from the network and a downtime notification message is automatically communicated indicating that the web server is offline. In another embodiment, events may be created to schedule downtime for web-based applications, including websites. Prior to the scheduled downtime, requests to a web-based application may be automatically stopped and redirected to a specified location. In another embodiment, the operation of web servers is automatically monitored to detect the presence of a fault condition and, if a fault condition is present, then a determination may be made that the affected web servers are down and requests to the down web servers are automatically redirected to an alternate server. | 01-01-2009 |
Sean Lamont Grant Livingston, Bothell, WA US
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20090320108 | Generating And Changing Credentials Of A Service Account - Technologies are described herein for generating and changing credentials of a service account. In one method, a credential schedule is retrieved. The credential schedule specifies when a plurality of credentials are scheduled to be changed. A determination is made whether a current credential associated with the service account is scheduled to be changed according to the credential schedule. Upon determining that the current credential is scheduled to be changed, at least part of a new credential is generated. The current credential is replaced with the new credential for the service account. | 12-24-2009 |
20110321029 | UPGRADE MANAGEMENT OF APPLICATION COMPONENTS - Architecture that enables separation of a user interface (UI) upgrade from the content and application logic upgrade. Administrators can upgrade to take advantage of new infrastructure features, and independently schedule the UI upgrade, for example, to accommodate customization work or to ensure user training. Furthermore, administrators can now allow users to choose when to switch to the new UI. More specifically, the architecture facilitates the separation of a UI upgrade from content and application logic upgrade, the ability to control the UI upgrade at multiple levels of precision, the ability for application logic and UI components to change behaviors based on the UI version of the context, and the ability to “preview” the updated UI before permanently switching to it. Additionally, UI components can be filtered to only appear in the appropriate UI version, and the site's UI version can be compared to versions that a component is compatible with. | 12-29-2011 |
Sean Lamont Grant Livingston, Kirkland, WA US
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20130117738 | Server Upgrades with Safety Checking and Preview - Upgrade control checks may be provided. A user may be notified that at least one upgrade is available. In response to receiving a selection of the at least one upgrade from the user, a check may be made to determine whether the at least one upgrade conflicts with an existing component. If no conflict is detected, the upgrade may be performed. If a conflict does exist, a repair may be attempted. | 05-09-2013 |
Susan Livingston, Clarkston, MI US
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20090295681 | Virtual Image System for Windshields - A virtual image system for windshields that permits an image source to reflect off the windshield so that a virtual image, free of ghost image, is visible to the driver. Either a matte black material is applied to a windshield glass pane at any of the outer glass pane windshield surfaces | 12-03-2009 |
Tracy Livingston, Heber City, UT US
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20100226785 | STRUCTURAL TOWER - A structural tower having a space frame construction for high elevation and heavy load applications is disclosed, with particular application directed to wind turbines. The structural tower includes damping or non-damping struts in the longitudinal, diagonal or horizontal members of the space frame. One or more damping struts in the structural tower damp resonant vibrations or vibrations generated by non-periodic wind gusts or sustained high wind speeds. The various longitudinal and diagonal members of the structural tower may be secured by pins, bolts, flanges or welds at corresponding longitudinal or diagonal joints of the space frame. | 09-09-2010 |
20100236161 | LIFTING SYSTEM AND APPARATUS FOR CONSTRUCTING AND ENCLOSING WIND TURBINE TOWERS - An apparatus and method for mounting a wind turbine and blade assembly on the upper end of a wind turbine tower. In one aspect the apparatus generally includes a ginpole that is used to assemble the tower and a lifting frame or truss that is removably secured to a top bay assembly of the tower using the ginpole. The lifting frame or truss is operated using either cables or hydraulic rams and extends fore of the tower when the frame or truss is in a first position and generally above the tower when in a second position. When in the first position, a wind turbine or blade assembly can be hoisted to the top of the tower. The wind turbine or blade assembly is then moved into position for mounting to the tower as the frame or truss is pivoted to a second position. When the turbine and blade assembly are secured to the tower, the frame or truss is disconnected from the tower and lowered to the ground followed by the ginpole being lowered to the ground. | 09-23-2010 |
Wes Livingston, Athens, GA US
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20110096503 | Utilization of Data Center Waste Heat for Heat Driven Engine - A method and system of utilizing waste heat from a plurality of data center equipment comprising the steps of collecting waste heat from a plurality of data center equipment and utilizing said waste heat as the driving heat input for a heat driven engine. Heat recovery means collects waste heat from heat-producing equipment and transfers it in the form of hot water to drive a heat driven engine such as a chiller or heat pump. The output of the heat driven engine may be put to many productive uses, thereby reducing the over all energy load on the data center. | 04-28-2011 |
Wes Livingston, Athans, GA US
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20110132550 | Single Chamber Adsorption Concentrator - A single chamber adsorption concentrator unit is described that utilizes low grade heat to drive an adsorbent/adsorbent working pair to separate a solvent from a solute/solvent mixture. One preferred application of the device of the present invention is separating water from the salt brine produced by the aluminum smelting industry. The brine solution is introduced into a single chamber shell proximate the concentrator evaporator where the water in the brine can freely evaporate and the resulting water vapor freely flow without inhibition to be either absorbed into the adsorbent modules or condensed by the condenser. The free flow of water vapor is facilitated by continuous operation of the condenser and by maintaining the brine solution at a higher temperature than the cooling fluid driving the condenser. A mist eliminator with a wash down feature located intermediate to the evaporator and the silica gel is provided to collect contaminants that may be carried from the evaporator by the vigorous boiling. | 06-09-2011 |
William Tyler Livingston, New Iberia, LA US
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20080257558 | Shifting apparatus and method - A device for shifting a sliding sleeve. The sliding sleeve is concentrically positioned within a well, and wherein the well is in communication with a hydrocarbon reservoir. In the most preferred embodiment, the device comprises an outer housing forming an annulus with the well and a power piston slidably disposed within the outer housing. The power piston includes an upper shoulder configured to form an annular chamber and a tubular chamber relative to the outer housing, a lower shoulder configured to form an atmospheric chamber relative to the outer housing. The device further comprises a first latch for preventing upward movement of the power piston, a second latch for preventing downward movement of the power piston, and wherein movement of the power piston shifts the sliding sleeve. | 10-23-2008 |