Liu, Cambridge
Andong Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140314982 | GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE - Presented herein are articles and methods featuring substrates with thin, uniform polymeric films grafted (e.g., covalently bonded) thereupon. The resulting coating provides significant reductions in thermal resistance, drop shedding size, and degradation rate during dropwise condensation of steam compared to existing coatings. Surfaces that promote dropwise shedding of low-surface tension condensates, such as liquid hydrocarbons, are also demonstrated herein. | 10-23-2014 |
Boshu Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20150032730 | Data Analysis Engine - A system and method of analyzing data receives a user-specified selection of a data source, a user-specified selection of a type of data representation, and a user-specified description of a view to be constructed in accordance with the user-specified selection of the type of data representation. An application program interface (API) function generates a multidimensional query based on the user-specified type of data representation and the user-specified description of the view to be constructed, and submits the multidimensional query to the an On-line Analytical Processing (OLAP) server. The application program interface (API) function receives a multidimensional response from the OLAP server containing results acquired by the multidimensional query of the data source, and generates the view based on the results contained in the multidimensional response and in accordance with the user-specified selection of the type of data representation and the user-specified description of the view. | 01-29-2015 |
Ce Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100054694 | COMBINED VISUAL AND AUDITORY PROCESSING - A computer-implemented method includes segmenting a plurality of video frames of a sequence of video frames into a first portion that includes a selected visual object represented in the video frame and a second portion that includes a background represented in the video frame. The selected visual object is selected by using a selection envelope. | 03-04-2010 |
David V. Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110091412 | MUTANT INTERLEUKIN-2 (IL-2) POLYPEPTIDES - The present invention relates to mutant IL-2 polypeptides that act as receptor antagonists. The mutant IL-2 polypeptides bind CD 25 but do not activate the IL-2 receptor. Also provided are methods of using the mutant IL-2 polypeptides, for example, to treat a patient who has cancer or a viral infection. The mutant polypeptides can also be used in various delivery systems. | 04-21-2011 |
Donglei Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100168082 | Heterobicyclic Carboxamides as inhibitors for kinases - The invention relates to novel organic compounds of formula (I) | 07-01-2010 |
| 20120245187 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 09-27-2012 |
| 20130005750 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 01-03-2013 |
| 20130005751 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 01-03-2013 |
| 20130005753 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 01-03-2013 |
| 20130012529 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 01-10-2013 |
Haiqun Liu, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090297524 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of CD40L. In one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of CD40L, preferably without substantially agonizing CD40 and/or CD40L activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/CD40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 12-03-2009 |
| 20100092482 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC40L. in one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC40L, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/DC40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 04-15-2010 |
| 20100092483 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC40L. in one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC40L, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/DC40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 04-15-2010 |
| 20110172400 | COMPOSITIONS MONOVALENT FOR CD40L BINDING AND METHODS OF USE - The invention relates to antibody polypeptides that monovalently bind CD4OL. Antibody polypeptides that are monovalent for binding of CD4OL can inhibit CD4OL activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC4OL. in one aspect, a monovalent anti-CD4OL antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC4OL, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD4OL antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD4OL interactions in an individual and methods of treating diseases or disorders involving CD40/DC4OL interactions, the methods involving administering a monovalent anti-CD4OL antibody polypeptide to the individual. | 07-14-2011 |
| 20130041136 | LIGANDS THAT HAVE BINDING SPECIFICITY FOR EGFR AND/OR VEGF AND METHODS OF USE THEREFOR - Disclosed are ligands that have binding specificity for vascular endothelial growth factor (VEGF), for epidermal growth factor receptor (EGFR), or for VEGF and EGFR. Also disclosed are methods of using these ligands. In particular, the use of these ligands for cancer therapy is described. | 02-14-2013 |
| 20130129746 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 05-23-2013 |
| 20130202597 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 08-08-2013 |
| 20130230519 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14-10, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 09-05-2013 |
| 20130266567 | ANTI-SERUM ALBUMIN BINDING SINGLE VARIABLE DOMAINS - The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts. | 10-10-2013 |
| 20140140996 | ANTI-SERUM ALBUMIN BIDING VARIABLE DOMAINS - The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts. | 05-22-2014 |
| 20160052998 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 02-25-2016 |
Jifeng Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080199123 | ULTRAFAST GE/SI RESONATOR-BASED MODULATORS FOR OPTICAL DATA COMMUNICATIONS IN SILICON PHOTONICS - An optical modulator structure includes at least two waveguide structures for inputting and outputting an optical signal. At least one ring resonator structure provides coupling between the at least two waveguide structures. The at least one ring resonator structure includes Ge or SiGe. | 08-21-2008 |
| 20100307579 | Pseudo-Periodic Structure for Use in Thin Film Solar Cells - A method of manufacturing a photovoltaic cell includes providing an active absorption layer, forming a pseudo-periodic grating adjacent to the active absorption layer, and forming a reflector adjacent to the pseudo-periodic grating. A photovoltaic cell includes an active absorption layer, a pseudo-periodic grating adjacent to the active absorption layer, and a reflector adjacent to the pseudo-periodic grating. | 12-09-2010 |
| 20110316018 | ENGINEERING EMISSION WAVELENGTHS IN LASER AND LIGHT EMITTING DEVICES - A light emitting device is provided that includes at least one first semiconductor material layers and at least one second semiconductor material layers. At least one near-direct band gap material layers are positioned between the at least one first semiconductor layers and the at least one second semiconductor material layers. The at least one first semiconductor layers and the at least one second material layers have a larger band gap than the at least one near-direct band gap material layers. The at least one near-direct band gap material layers have an energy difference between the direct and indirect band gaps of less than 0.5 eV. | 12-29-2011 |
Jingjing Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090292685 | VIDEO SEARCH RE-RANKING VIA MULTI-GRAPH PROPAGATION - A video search re-ranking via multi-graph propagation technique employing multimodal fusion in video search is presented. It employs not only textual and visual features, but also semantic and conceptual similarity between video shots to rank or re-rank the search results received in response to a text-based search query. In one embodiment, the technique employs an object-sensitive approach to query analysis to improve the baseline result of text-based video search. The technique then employs a graph-based approach to text-based search result ranking or re-ranking. To better exploit the underlying relationship between video shots, the re-ranking scheme simultaneously leverages textual relevancy, semantic concept relevancy, and low-level-feature-based visual similarity. The technique constructs a set of graphs with the video shots as vertices, and the conceptual and visual similarity between video shots as hyperlinks. A modified topic-sensitive PageRank algorithm is then applied to these graphs to determine the overall relevancy ranking. | 11-26-2009 |
| 20120158703 | SEARCH LEXICON EXPANSION - One or more techniques and/or systems are disclosed for creating an expanded or improved lexicon for use in search-based semantic tagging. A set of first documents can be identified using a set of first lexicon elements as queries, and one or more first document patterns can be extracted from the set of first documents. The document patterns can be used to find one or more second documents in a query log that comprise the document patterns, which are associated with query terms used to return the second documents. The query terms for the second documents can be extracted and used to expand the lexicon. Elements within the lexicon may be weighted based upon relevance to different query domains, for example. | 06-21-2012 |
Likai Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130018911 | Variable-Length Nonce GenerationAANM Liu; LikaiAACI CambridgeAAST MAAACO USAAGP Liu; Likai Cambridge MA US - Methods and systems for obtaining a scalable variable-length nonce are provided. An exemplary method for obtaining a scalable variable-length nonce includes obtaining an initial nonce candidate. The exemplary method also includes transmitting a query to determine whether the initial nonce candidate has already been assigned. When the initial nonce candidate has already been assigned, a combined nonce candidate is obtained. The combined nonce candidate includes characters appended to the initial nonce candidate. An exemplary system for obtaining a scalable variable-length nonce includes a transmitting engine that transmits a request associated with a current token. The exemplary system also includes a receiving engine that receives a message associated with the current token. The exemplary system further includes a token acquiring engine that obtains a new token, and an appending engine that appends the new token to the current token. | 01-17-2013 |
Mei Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090155786 | COMPOSITIONS AND METHODS FOR DETECTING MARKERS OF CANCER - Disclosed herein are compositions and methods for detecting one or more markers indicative of cancer. In one instance the marker is one or more methylated genes, such as SFRPs. In another instance the marker is an altered protein, such as p53. | 06-18-2009 |
Ming-Yu Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140219547 | Method for Increasing Resolutions of Depth Images - A resolution of a low resolution depth image is increased by applying joint geodesic upsampling to a high resolution image to obtain a geodesic distance map. Depths in the low resolution depth image are interpolated using the geodesic distance map to obtain a high resolution depth image. The high resolution image can be a gray scale or color image, or a binary boundary map. The low resolution depth image can be acquired by any type of depth sensor. | 08-07-2014 |
| 20150324659 | METHOD FOR DETECTING OBJECTS IN STEREO IMAGES - A method detects an object in a pair of stereo images acquired of a scene, by first generating a cost volume from the pair of stereo images, wherein the cost volume includes matching costs for a range of disparity values, for each pixel the sterao images, between the stereo images in the pair. Feature vectors are determined from sub-images in the cost volume using a feature function of the disparity values with a minimal accumulated cost within regions inside the sub-images. Then, a classifier is appled to the feature vectors to detect whether the sub-image includes the object. | 11-12-2015 |
Shan Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090003457 | Inverse Tone Mapping for Bit-Depth Scalable Image Coding - A method performs inverse tone mapping of an image in a decoder. For each block of each color channel of the image the following steps are performed. A scaling factor is determined for a current block of the image by adding a predicted scaling factor for the current block to a difference between the predicted scaling factor and the scaling factor of an adjacent block. An offset value for the current block is determined by adding a predicted offset for the current block to a difference between the predicted offset value and the offset value of the adjacent block. The scaling factor and the offset value are applied to pixel intensity values of the current block to produce a mapped block in which a bit-depth of the mapped block is greater than the bit-depth of the current block. | 01-01-2009 |
| 20090003718 | Inverse Tone Mapping for Bit-Depth Scalable Image Coding Adapted to Variable Block Sizes - A method performs inverse tone mapping of an image in a decoder. For each block of each color channel of the image a scaling factor is determined by adding a predicted scaling factor for the current block to a difference between the predicted scaling factor and the scaling factor of an adjacent block. An offset value for the current block is determined by adding a predicted offset for the current block to a difference between the predicted offset value and the offset value of the adjacent block. The scaling factor and the offset value are applied to pixel intensity values of the current block to produce a mapped block. The inverse tone mapping can also be applied to blocks of different sizes. | 01-01-2009 |
| 20090267825 | Method and Apparatus for Compressing SAR Signals - A method compresses synthetic aperture radar (SAR) data by sampling the SAR data into blocks and transforming each block to a corresponding block of transform coefficients. Each block of transform coefficient is quantized according to a quantization parameter to obtain a corresponding block of quantized transform coefficients, which are demultiplexed into sets of blocks of quantized transform coefficients. The quantized transform coefficients in the blocks in each set are arithmetically encoding in parallel according to a probability model to produce an intermediate bitstream for each set of blocks. The encoding of the quantized transform coefficients of one block is independent of the quantized transform coefficients of a successive block. The intermediate of bitstreams are then multiplexed to a compressed bitstream, which can be transmitted, or stored, for subsequent decoding to construct an SAR image. | 10-29-2009 |
| 20130022121 | METHODS AND APPARATUS FOR CONCEALING CORRUPTED BLOCKS OF VIDEO DATA - Corrupted subdivision s of streaming data are concealed using a matching subdivision in a previously reconstructed reference picture. The matching subdivision is located by applying a recovered motion vector to a co-located subdivision in the reference picture for which motion vector information has been lost. The recovered motion vector is obtained using a reference motion vector from an available neighboring subdivision of the co-located subdivision. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. This abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. | 01-24-2013 |
Sijia Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090217206 | MODELESS INTERACTION WITH GUI WIDGET APPLICATIONS - A user displayed interactive GUI widget (icon) provides two or more regions. A first region provides widget manipulation function for editing the widget, editing including moving or sizing functions. A second region provides widget interaction function for user interaction with the widget including interaction lists or interaction graphics. The regions may comprise one or more icon border regions and one or more icon internal regions. | 08-27-2009 |
Sophie Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20150247832 | GAS SENSORS BASED UPON METAL CARBON COMPLEXES - A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region including a conductive material and an alkene-interacting metal complex. | 09-03-2015 |
Tianxiang Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20160068402 | METHOD FOR PREPARING ZEOLITE SSZ-52 - A method is disclosed for synthesizing zeolite SSZ-52 in the presence of an organic structure directing agent having the following structure (1): | 03-10-2016 |
| 20160068403 | METHOD FOR PREPARING ZEOLITE SSZ-52 USING COMPUTATIONALLY PREDICTED STRUCTURE DIRECTING AGENTS - A method is disclosed for preparing zeolite SSZ-52 using a computationally predicted organic structure directing agent. The computationally predicted structure organic directing agent is an organic structure directing agent other than an N,N-diethyl-5,8-dimethyl-azonium bicyclo[3.2.2.]nonane cation, and the difference in stabilization energy between the organic structure directing agent other than an N,N-diethyl-5,8-dimethyl-azonium bicyclo[3.2.2.]nonane cation and the N,N-diethyl-5,8-dimethyl-azonium bicyclo[3.2.2.]nonane cation is no more than 2.5 kJ mol | 03-10-2016 |
Tieming Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080235160 | METHOD AND APPARATUS FOR JOINT PRICING AND RESOURCE ALLOCATION UNDER SERVICE-LEVEL AGREEMENT - There are provided an apparatus, a method, and a computer program product for joint determination of price and resource allocation. The apparatus includes a price and resource allocation determination device for jointly determining a price and a resource allocation for a given item or service offered for use or sale by a given e-retailer to optimize a pre-specified objective for the given e-retailer. | 09-25-2008 |
Vincent H. Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140004503 | Device and Method for Sampling Bodily Fluid for Medical Analytes in Ultra Low Concentrations | 01-02-2014 |
Vincent Hok Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130046164 | Implantable Dissolved Oxygen Sensor and Methods of Use - A sensor is provided for measuring a dissolved oxygen concentration in vivo when implanted at a tissue site and in ex vivo applications. The sensor includes an article comprising a sensing medium retained within the implantable article by an oxygen-permeable material. The sensing medium comprises an MR contrast agent for oxygen. The sensor is configured to indicate the dissolved oxygen concentration of a fluid, e.g., in vivo at the tissue site, when subjected to an MR-based method. | 02-21-2013 |
Wenhao Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110037029 | Copolymer-associated nanomaterial - A nanomaterial can include an outer layer including a ligand. The ligand can include a first monomer unit including a first moiety having affinity for a surface of the nanocrystal, a second monomer unit including a second moiety having a high water solubility, and a third monomer unit including a third moiety having a selectively reactive functional group or a selectively binding functional group. The ligand can be a random copolymer. | 02-17-2011 |
| 20110059467 | CONTROLLED MODIFICATION OF SEMICONDUCTOR NANOCRYSTALS - A controlled valency semiconductor nanocrystal can have a desired number of compounds associated with it. The semiconductor nanocrystal can have exactly one compound associated with it, and the compound can have exactly one binding site for an affinity target. The semiconductor nanocrystal can be used to image single copies of cell-surface proteins. | 03-10-2011 |
| 20110129420 | MATERIALS AND METHODS FOR BIOLOGICAL IMAGING - Water soluble InAs(ZnCdS) semiconductor nanocrystals with bright and stable emission in the near infrared (NIR) wavelength range have been prepared. The NIR semiconductor nanocrystals can be functionalized to enable imaging of specific cellular proteins. In addition, the utility of the NIR region for in vivo biological imaging is clearly demonstrated by the superior ability of InAs(ZnCdS) semiconductor nanocrystals to image tumor vasculature. | 06-02-2011 |
Xinbing Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080273836 | ULTRAFAST LASER MACHINING SYSTEM AND METHOD FOR FORMING DIFFRACTIVE STRUCTURES IN OPTICAL FIBERS - An ultrafast laser machining system and method to form diffractive structures in optical fibers. The fiber is mounted with its longitudinal axis perpendicular to the beam path of the laser pulses. A region of the fiber is illuminated and then imaged with two cameras. These cameras are aligned substantially orthogonally. A position of the beam spot is determined. The beam spot is aligned to a starting position within the region. This position is within a portion of the fiber to be machined for which the beam path passes through the greatest length of material. The beam spot is scanned along a path designed to pass the beam spot through all of the portion to be machined such that the beam path does not pass through previously machined material. The laser pulses, which have a duration of less than about 1 ns, are generated as the beam spot is scanned. | 11-06-2008 |
Xinxue Liu, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20150105265 | METHODS TO ASSESS THE LIKELIHOOD OF DYSPLASIA OR ESOPHAGEAL ADENOCARCINOMA - In some embodiments, a method for aiding assessment of the likelihood of dysplasia or esophageal adenocarcinoma being present in a subject can include (a) providing an esophagal sample from said subject (b) determining the methylation status of (i) SLC22A18, (ii) PIGR, (iii) GJA12 and (iv) RIN2 in said sample wherein if 2 or more of said genes are methylated then an increased likelihood of presence of dysplasia or esophageal is determined. The invention also relates to apparatus for same. | 04-16-2015 |
Xinyu Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130034869 | DEVICES AND METHODS FOR MULTIPLEXED ASSAYS - The disclosure provides low cost, portable three-dimensional devices for performing multiplexed assays. The devices comprise at least two substantially planar layers disposed in parallel planes, wherein one of the layers is movable relative to each other parallel to the planes to permit the establishment of fluid flow communication serially between the two layers. | 02-07-2013 |
| 20140183059 | MICROFLUIDIC DEVICES FOR MULTIPLEXED ELECTROCHEMICAL DETECTION - The multiplexed electrochemical microfluidic paper-based analytical device comprises multiple detection zones for the detection of multiple biochemical analytes from one single sample. Cavity valves integrated on the device will deliver the sample to different detection zones. These analytes include, but are not limited to, urea, creatinine, creatine, glucose, lactate, ethanol, uric acid, cholesterol, pyruvate, creatinine, β-hydroxybutyrate, alanine aminotrasferase, aspartate aminotransferase, alkaline phosphatase, and acetylcholinesterase (or its inhibitors). This system will provide a simple and low-cost POC approach to obtain quantitative and multiple biological information from one sample (e.g. one drop of blood). | 07-03-2014 |
Yanyan Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090298191 | Lateral Flow and Flow-through Bioassay Devices Based On Patterned Porous Media, Methods of Making Same, and Methods of Using Same - Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. | 12-03-2009 |
| 20130128036 | Lateral Flow and Flow-through Bioassay Devices Based on Patterned Porous Media, Methods of Making Same, and Methods of Using Same - Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. | 05-23-2013 |
| 20140234881 | LATERAL FLOW AND FLOW-THROUGH BIOASSAY DEVICES BASED ON PATTERNED POROUS MEDIA, METHODS OF MAKING SAME, AND METHODS OF USING SAME - Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. | 08-21-2014 |
Yinglin Liu, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20130176661 | Apparatus and Associated Methods - An apparatus, the apparatus including first and second circuit boards, and an electrolyte, the first and second circuit boards each including a capacitive element, wherein the apparatus is configured such that a chamber is defined between the first and second circuit boards with the capacitive elements contained therein and facing one another, the chamber including the electrolyte, and wherein the apparatus is configured to store electrical charge when a potential difference is applied between the capacitive elements. | 07-11-2013 |
| 20130309527 | Apparatus and Associated Methods - An electrode, the electrode including a conducting layer configured to act, in use, as a charge collector to provide an electrical path for generated and/or stored charge through the conducting layer; a barrier layer, the barrier layer configured to cover a portion of a surface of said conducting layer such that, when the electrode is in contact with an electrolyte, the electrolyte is prevented from substantially contacting and corroding the conducting layer at the covered portion; and an active electrode element configured for use in generation and/or storing charge, the active electrode element positioned in a non-covered portion in electrical contact with the conducting layer to prevent the electrolyte from substantially contacting and corroding the conducting layer in the non-covered portion and to also be exposed to said electrolyte to allow for the generation and/or storage of charge and provide the generated/stored charge to the conducting layer. | 11-21-2013 |
| 20140050988 | Apparatus and Associated Methods - An apparatus including a layer of electrically conductive material with an open interconnected wall structure of electrically conductive material formed thereon, the open interconnected wall structure having a gyroid structure including one or more open pores into which an active material for use in generating and/or storing electrical charge can be deposited, wherein the layer of electrically conductive material and the open interconnected wall structure together form a charge collector which provides an electrical path from the active material for the generated and/or stored electrical charge. | 02-20-2014 |
| 20140057147 | Method and Apparatus For Flexible Battery - In accordance with an example embodiment of the present invention, an apparatus is disclosed. The apparatus includes a single battery ribbon and vacuum packaging. The single battery ribbon includes a first portion, a second portion, and an interconnecting portion between the first portion and the second portion. The first portion includes a first block. The second portion includes a second block. The first portion, the second portion, and the interconnecting portion form a continuous single layer including an anode and a cathode. The vacuum packaging surrounds the single battery ribbon. The vacuum packaging includes a middle connecting portion configured to contact a first side of the interconnecting portion and a second opposite side of the interconnecting portion. | 02-27-2014 |
| 20140315084 | METHOD AND APPARATUS FOR ENERGY STORAGE - In accordance with an example embodiment of the present invention, apparatus is provided comprising first and second electrodes, first and second current collectors, an electrolyte, and a first contact layer; wherein the electrolyte is configured to separate the first and second electrodes; and wherein the first contact layer is configured to form an electrical contact between the first current collector and the first electrode. | 10-23-2014 |
| 20150332867 | Supercapacitor Having A Circuit Board Defining An Electrolyte Chamber - An apparatus, the apparatus including first and second circuit boards, and an electrolyte, the first and second circuit boards each including a capacitive element, wherein the apparatus is configured such that a chamber is defined between the first and second circuit boards with the capacitive elements contained therein and facing one another, the chamber including the electrolyte, and wherein the apparatus is configured to store electrical charge when a potential difference is applied between the capacitive elements. | 11-19-2015 |
| 20160072332 | Flexible, Hybrid Energy Generating And Storage Power Cell - An apparatus includes a separator/electrolyte assembly; a first energy storage portion disposed on a first surface of the separator/electrolyte assembly; a second energy storage portion disposed on a second surface of the separator/electrolyte assembly; a first metallized piezoelectric film disposed on the first energy storage portion; and a second metallized piezoelectric film disposed on the second energy storage portion. When a force is applied to the first metallized piezoelectric film, a piezoelectric effect converts mechanical strain into electric potential and each energy storage portion stores the energy converted in the first energy storage portion and the second energy storage portion for subsequent discharge from the first energy portion and the second energy storage portion to an electronic device. | 03-10-2016 |
Yun Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140371610 | METHOD AND APPARATUS FOR BEAT-SPACE FREQUENCY DOMAIN PREDICTION OF CARDIOVASCULAR DEATH AFTER ACUTE CORONARY EVENT - A method for the machine generation of a model for predicting patient outcome following the occurrence of an event. In one embodiment the method includes the steps of obtaining a physiological signal of interest, the physiological signal having a characteristic; obtaining a time series of a signal characteristic; dividing the time series into a plurality of window segments; converting the time series from time-space to beat-space; computing the power in various frequency bands of each window segment; computing the 90th percentile of the spectral energies across all window segments for each frequency band; and inputting the data into a machine learning program to generate a weighted risk vector. | 12-18-2014 |
Zan Liu, Cambridge, MA US
| Patent application number | Description | Published |
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| 20140117283 | Reversible Sorbent for Warm CO2 Capture by Pressure Swing Adsorption - Sorbent for reversible warm CO | 05-01-2014 |
| 20150110696 | Reversible Sorbent for Warm CO2 Capture by Pressure Swing Adsorption - Sorbent for reversible warm CO | 04-23-2015 |
Zhenming Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130246608 | COUNT TRACKING IN DISTRIBUTED ENVIRONMENTS - Count tracking in distributed environments is described, for example, as in data centers where many sites receive data and a coordinator node estimates a sum of the data received across the sites. Count tracking may be used in database applications, search engines, social networking applications and others. In various embodiments sites and a coordinator node work together to implement a process for summing data received at sites, where the sum takes into account both increments and decrements. In examples, a site decides whether to notify the coordinator node of a new data item according to a sampling probability that is related to an estimate of the current global sum of the data input across sites. In some examples a multi-mode algorithm is implemented which increases or decreases communication between the sites and the coordinator node according to behavior of the estimated global sum such that communications costs are optimized. | 09-19-2013 |
Zhenyu Liu, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20130270575 | SEMICONDUCTOR WAFER COMPRISING GALLIUM NITRIDE LAYER HAVING ONE OR MORE SILICON NITRIDE INTERLAYER THEREIN - A semiconductor wafer comprising a substrate layer and a first GaN layer having one or more SiNx interlayers therein, wherein in the first GaN layer at least one SiNx interlayer has GaN penetrated through one or more portions of said SiNx interlayer and preferably has a thickness of from 0.5 to 10 nm. | 10-17-2013 |