Patent application number | Description | Published |
20090156627 | THERAPEUTIC COMPOUNDS - The invention provides compounds of formula I: | 06-18-2009 |
20090239871 | SOLUBILIZED TOPOISOMERASE POISONS - The invention provides compounds of formula I: | 09-24-2009 |
20100111874 | METHOD OF CANCER DETECTION AND TREATMENT - The present invention provides methods for detecting and treating cancer. In some embodiments, levels of ISG15 are determined, and topoisomerase I and II inhibitors as well as other DNA-damaging agents plus agents that increase the expression of ISG15 are selected and administered. | 05-06-2010 |
20110136812 | SOLUBILIZED TOPOISOMERASE POISONS - The invention provides compounds of formula I: | 06-09-2011 |
20110275596 | METHODS FOR TREATING NEOPLASIA AND FOR IDENTIFYING COMPOSITIONS USEFUL IN SUCH THERAPY - Various methods for treating a patient with neoplasia are disclosed, in particular, methods using topoisomerase Ila-preferential poisons, methods using a combination of a topoisomerase Illi-preferential inhibitor and a topoisomerase II poison, and methods using a combination of a topoisomerase II poison and a proteasome inhibitor are disclosed. Novel topoisomerase Ila-preferential poisons are disclosed, particularly, several novel 13-carboline derivatives are identified. Methods for identifying the novel topoisomerase Ila-preferential poisons and methods for identifying the novel topoisomerase EP-preferential inhibitors are also provided herein. | 11-10-2011 |
20140235578 | METHODS FOR TREATING NEOPLASIA AND FOR IDENTIFYING COMPOSITIONS USEFUL IN SUCH THERAPY - Various methods for treating a patient with neoplasia are disclosed, in particular, methods using topoisomerase Ila-preferential poisons, methods using a combination of a topoisomerase Illi-preferential inhibitor and a topoisomerase II poison, and methods using a combination of a topoisomerase II poison and a proteasome inhibitor are disclosed. Novel topoisomerase Ila-preferential poisons are disclosed, particularly, several novel 13-carboline derivatives are identified. Methods for identifying the novel topoisomerase Ila-preferential poisons and methods for identifying the novel topoisomerase EP-preferential inhibitors are also provided herein. | 08-21-2014 |
Patent application number | Description | Published |
20090035704 | Underlayer Coating Composition Based on a Crosslinkable Polymer - The present invention relates to an underlayer coating composition capable of being crosslinked comprising a polymer, a compound capable of generating a strong acid, and optionally a crosslinker, where the polymer comprises at least one absorbing chromophore and at least one moiety selected from an epoxy group, an aliphatic hydroxy group and mixtures thereof. | 02-05-2009 |
20090130591 | Antireflective Coating Composition and Process Thereof - The present invention relates to an antireflective composition comprising a polymer, a thermal acid generator and optionally a crosslinking agent, where the polymer comprises at least one hydrophobic unit (1), at least one chromophore unit (2), at least one unit with a crosslinking site (3) and optionally a unit capable of crosslinking the polymer, | 05-21-2009 |
20100015550 | DUAL DAMASCENE VIA FILLING COMPOSITION - Compositions for use in dual damascene process are disclosed. | 01-21-2010 |
20100063169 | PHOSPHORAMIDE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME - Certain cyclic phosphoramide ester compounds useful, inter alia, as halogen-free flame-retardant compounds, are disclosed. The compounds are particularly useful for providing flame retarded polyurethane foams. (I) | 03-11-2010 |
20100092894 | Bottom Antireflective Coating Compositions - Antireflective coating compositions are discussed. | 04-15-2010 |
20100137465 | PHOSPHATE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME - Certain cyclic phosphate ester compounds useful, inter alia, as halogen-free flame-retardant compounds, are disclosed. The compounds are particularly useful for providing flame retarded polyurethane foams. (I) | 06-03-2010 |
20110250544 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS - Antireflective coating compositions are discussed. | 10-13-2011 |
20130337380 | POSITIVE PHOTOSENSITIVE MATERIAL - The invention relates to a novel positive working photosensitive composition having: at least one photoacid generator; at least one novolak polymer; at least one polymer, having a polymer backbone, said polymer comprising a structure of the following formula: | 12-19-2013 |
20130337381 | NEGATIVE-WORKING THICK FILM PHOTORESIST - Disclosed are compositions for negative-working thick film photophotoresists based on acrylic co-polymers. Also included are methods of using the compositions. | 12-19-2013 |
20140154624 | POSITIVE WORKING PHOTOSENSITIVE MATERIAL - Disclosed herein is a photosensitive composition comprising a heterocyclic thiol compound or tautomeric form thereof and its method of use on a substrate, which may include a chalcophile substrate. | 06-05-2014 |
Patent application number | Description | Published |
20080300410 | Organic Compounds - The present invention relates to salts of aryl compounds as discussed below and to methods of manufacture thereof, as well as other subject matter. More particularly, the invention relates to salts useful as intermediates for the synthesis of the cinnamanilide of formula (Y): where R | 12-04-2008 |
20090131408 | Organic Compounds - The present invention relates to novel aza-thia-benzoazulene derivatives of formula I as defined in the claims, their preparation, the use of these novel compounds for the preparation of pharmaceutical compositions, the use of these novel compounds and compositions for managing arthritis and arthritis-related conditions as well as in the treatment of pain in animals and humans. More particularly, the present invention relates to pharmaceutical, preferably veterinary compositions and methods for reducing inflammation and pain associated with acute inflammation of body parts, particularly joints, due to injury or due to arthritic conditions or other disease conditions. | 05-21-2009 |
20090137495 | Organic Compounds and Their Uses - The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases. | 05-28-2009 |
20090156585 | ORGANIC COMPOUNDS - A specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi are used in the treatment of hypertension. | 06-18-2009 |
20090247581 | Organic Compounds - The present invention relates to a process for the synthesis of (S)-2′[2-1-(methyl-2-piperidyl) ethyl] cinnamanilide (I) or salts or pharmaceutically acceptable prodrugs thereof: | 10-01-2009 |
20110251170 | NEW POLYMORPHIC FORM OF 1-(4--2-ETHYL-BENZYL)-AZETIDINE-3-CARBOXYLIC - This invention relates to a novel crystalline form (Form A) of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this crystalline form, to processes for forming it and to its use in medical treatment. | 10-13-2011 |
20110257150 | NEW SALTS - This invention relates to a hydrochloride, malate, oxalate and tartrate salt forms of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of each of these salts, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment. | 10-20-2011 |
20120122836 | POLYMORPHIC FORM OF 1-(4--2-ETHYL-BENZYL)-AZETIDINE-3-CARBOXYLIC - This invention relates to a novel crystalline form (Form A) of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this crystalline form, to processes for forming it and to its use in medical treatment. | 05-17-2012 |
20120252778 | PYRAZOLO PYRIMIDINE DERIVATIVES - The present invention relates to pyrazolo pyrimidine derivatives, to methods of preparing these, to combinations and pharmaceutical composition comprising these, and to their use in the treatment of diseases and disorders which may for example involve autoimmune diseases, angiogenesis, pain, and/or inflammatory diseases. | 10-04-2012 |
20130225550 | SALTS - This invention relates to a hydrochloride, malate, oxalate and tartrate salt forms of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of each of these salts, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment. | 08-29-2013 |
20150057322 | COMPOUNDS CONTAINING S-N-VALERYL-N--VALINE AND (2R,4S)-5-BIPHENYL-4-YL-4-(3-CARBOXY-PROPIONYLAMINO)-2-METHYL-PENTANOIC ACID ETHYL ESTER MOIETIES AND CATIONS - A method for treatment of a cardiovascular or renal condition or disease with a specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi. | 02-26-2015 |
Patent application number | Description | Published |
20140352709 | Nail Polish Device - The invention provides a nail polish device for applying or removing nail polish. The nail polish device comprises a liquid delivering means for delivering a liquid nail polish or liquid nail polish removing composition; a main body structure substantially enclosing the liquid delivering means with an opening for receiving the fingers or toes of the user during use; and a vapor inhibiting material disposed on the main body structure, along the surface proximal to the liquid delivering means. The vapor inhibiting material is effective in inhibiting vapors and/or excess liquids from the liquid nail polish or removing composition by either absorbing same and/or neutralizing same. | 12-04-2014 |
20150328096 | ORAL CARE PRODUCTS COMPRISING TETRABASIC ZINC CHLORIDE AND TRIMETHYLGLYCINE - The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided. | 11-19-2015 |
20150328110 | ORAL GEL COMPRISING ZINC-AMINO ACID COMPLEX - Disclosed herein are dentifrices comprising a zinc amino acid halide, which provide a precipitate of zinc oxide upon use with dilution with water and/or saliva. Methods of making and using the dentifrices are also provided. | 11-19-2015 |
20150328111 | ORAL CARE PRODUCTS COMPRISING A TETRABASIC ZINC-AMINO ACID-HALIDE COMPLEX - Described herein are oral care compositions comprising a tetrabasic zinc halide and an amino acid; along with methods of making and using the same. | 11-19-2015 |
20150328112 | ORAL CARE PRODUCTS COMPRISING ZINC OXIDE AND TRIMETHYLGLYCINE - Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided. | 11-19-2015 |
20150328118 | ORAL CARE COMPOSITION COMPRISING ZINC AMINO ACID HALIDES - Disclosed herein are oral care compositions comprising a zinc amino acid halide. Methods of making and using the compositions are also provided. | 11-19-2015 |
20150328120 | ORAL CARE COMPOSITION COMPRISING AN AMADORI COMPOUND - The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject. | 11-19-2015 |
20150335552 | TEETH WHITENING METHODS, VISUALLY PERCEPTIBLE SIGNALS AND COMPOSITIONS THEREFOR - Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate. | 11-26-2015 |
20150335554 | ZINC AMINO ACID HALIDE MOUTHWASHES - Disclosed herein are mouthwashes comprising a complex of a zinc ion source acid. Methods of making and using the compositions are also provided. | 11-26-2015 |
20150342851 | TWO COMPONENT COMPOSITIONS CONTAINING ZINC AMINO ACID HALIDE COMPLEXES AND CYSTEINE - Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same. | 12-03-2015 |