Patent application number | Description | Published |
20120301952 | SYSTEM FOR HYPOTHERMIC TRANSPORT OF SAMPLES - A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend the sample in preservation fluid, and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature, while self-purging trapped gases. | 11-29-2012 |
20120309078 | METHODS AND DEVICES FOR PRESERVING TISSUES - Methods and apparatus for preserving detached tissues, especially digits and limbs, which are detached as a result of traumatic amputation. By using the methods and apparatus, detached tissues can be preserved for greater lengths of time and are ultimately in a better condition for replantation surgery. | 12-06-2012 |
20140041403 | SYSTEM FOR HYPERTHERMIC TRANSPORT OF BIOLOGICAL SAMPLES - A system for the hypothermic (2-8° C.) transport of biological samples, such as tissues, organs, or body fluids. The system includes a first transport container to suspend the sample in preservation fluid and provides an ability to monitor the temperature of the sample. The first transport container, holding the sample, is placed in an insulated second transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature. | 02-13-2014 |
20140045167 | METHODS FOR EVALUATING THE SUITABILITY OF AN ORGAN FOR TRANSPLANT - Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while monitoring viability by measuring oxygen consumption rates. | 02-13-2014 |
20140308653 | METHODS AND SYSTEMS FOR ASSESSING EX-VIVO ORGAN HEALTH - Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while monitoring viability by measuring oxygen consumption rates. | 10-16-2014 |
20140349273 | SYSTEM FOR HYPOTHERMIC TRANSPORT OF SAMPLES - A method for preserving an extracorporeal organ during hypothermic transport of the organ. The method includes placing an organ in a self-purging preservation apparatus to suspend the sample in preservation fluid, and filling the apparatus with a cold preservation solution. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature, thereby increasing the distance that the organ can be transported without compromising organ function. | 11-27-2014 |
20140356850 | APPARATUS FOR OXYGENATION AND PERFUSION OF TISSUE FOR ORGAN PRESERVATION - Systems and methods of the invention generally relate to prolonging viability of bodily tissue in static cold storage and hypothermic machine perfusion techniques by reducing the rate of edema through the application of compressive force to the bodily tissue via a compression device. Compression devices of the invention may comprise biocompatible materials and may apply compressive force through incorporation of elastic materials, through expandable bladders, or other means. Certain embodiments include perfusion devices comprising a pneumatic system, a pumping chamber, and an organ chamber. The pumping chamber is configured to diffuse a gas into a perfusate and to generate a pulse wave for moving the perfusate through a bodily tissue. The organ chamber is configured to receive the perfusate along with a bodily tissue fitted with a compression device. Both the organ chamber and the pumping chamber are configured to substantially automatically purge excess fluid. | 12-04-2014 |
20140356933 | APPARATUS FOR OXYGENATION AND PERFUSION OF TISSUE FOR ORGAN PRESERVATION - An apparatus according to an embodiment is configured to oxygenate and perfuse a bodily tissue for extracorporeal preservation of the bodily tissue. The apparatus includes a pneumatic system, a pumping chamber, and an organ chamber. The pneumatic system is configured for the controlled delivery of fluid to and from the pumping chamber based on a predetermined control scheme. The predetermined control scheme can be, for example, a time-based control scheme or a pressure-based control scheme. The pumping chamber is configured to diffuse a gas into a perfusate and to generate a pulse wave for moving the perfusate through a bodily tissue. The organ chamber is configured to receive the bodily tissue and the perfusate. The organ chamber is configured to substantially automatically purge excess fluid from the organ chamber to the pumping chamber. The pumping chamber is configured to substantially automatically purge excess fluid from the pumping chamber to an area external to the apparatus. | 12-04-2014 |
20150017627 | SYSTEM FOR HYPOTHERMIC TRANSPORT OF SAMPLES - A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature. | 01-15-2015 |