Lindquist, US
Alan Lindquist, Cincinnati, OH US
Patent application number | Description | Published |
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20080237142 | SYSTEMS AND METHODS FOR CONCENTRATING SUBSTANCES IN FLUID SAMPLES - Concentrator systems include a circulating fluid pathway passing through a pump, a filter, and a retentate container. An effluent outlet line communicates with the circulating fluid pathway through a filtering element within a body of the filter. The systems further include a control system. In some embodiments, the pump, filter, and retentate container may be secured within a portable container. Methods for concentrating a foreign substance within a fluid sample include establishing circulation of fluid through a fluid circulation path passing through a fluid pump, a filter body, and a retentate container. Fluid is caused to exit the fluid circulation path through a filtering element within the filter body, and at least one foreign substance is prevented from passing through the filtering element. A control system may be used to control at least one of a speed of the pump and a quantity of retentate within the retentate container. | 10-02-2008 |
20130239666 | Systems and Methods for the Detection of Low-Level Harmful Substances in a Large Volume of Fluid - A method and device for the detection of low-level harmful substances in a large volume of fluid comprising using a concentrator system to produce a retentate and analyzing the retantate for the presence of at one harmful substance. The concentrator system performs a method comprising pumping at least 10 liters of fluid from a sample source through a filter While pumping, the concentrator system diverts retentate from the filter into a container. The concentrator system also recirculates at least part of the retentate in the container again through the filter. The concentrator system controls the speed of the pump with a control system thereby maintaining a fluid pressure less than 25 psi during the pumping of the fluid; monitors the quantity of retentate within the container with a control system, and maintains a reduced volume level of retentate and a target volume of retentate. | 09-19-2013 |
Benjamin Lindquist, Tallahassee, FL US
Patent application number | Description | Published |
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20100031165 | System and method for creating gateway between an analytical database and a virtual world - Provided is a system and method for facilitating or creating a gateway to integrate with 3D virtual worlds (e.g., Second Life and Sun Wonderland) and external applications (e.g., data visualization gateways, process modeling systems, artificial intelligences, social networks, and other virtual worlds) for three-dimensional visualization of data in a virtual world. The visualization tool may include, for example, a three-dimensional graph using various colors, dimensions, shapes, and other properties as desired, to represent different data and data values. The avatars in the virtual world, as controlled by the game's players or users in the real world, can point to or otherwise interact with elements in the three-dimensional graph whereupon the base data or other related informational data would be displayed with respect to that given cell or element of the graph. | 02-04-2010 |
20150248779 | Displaying a Live Stream of Events Using a Dynamically-Constructed Three-Dimensional Data Tree - A dynamically configured tree form and corresponding graphical elements graphically represent information contained in a live stream of event data. The tree form is positioned in virtual three dimensional space within a computer graphical user interface such that the root of the tree is in the center of the screen, originating at the farthest distance from the viewer along the z axis. The tree form is configured to guide movement of the three dimensional graphical elements which represent individual measurements of events during specific time periods. The outermost, or leaf, portions of the tree represent the present time. The root or base of the tree represents the maximum duration that is being measured. | 09-03-2015 |
David B. Lindquist, Raleigh, NC US
Patent application number | Description | Published |
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20080313331 | Managing Computer Resources In A Distributed Computing System - Methods, apparatus, and products for managing computer resources in a distributed computing system are disclosed that include registering, in a configuration management database by a discovery module in response to a modification of a resource in a resource container, the resource in association with a configuration management database identifier, the resource characterized by a resource type and a resource identification, the resource container including a manageability endpoint characterized by a manageability endpoint reference; and managing the resource by a management module in dependence upon a resource management policy and the manageability endpoint reference, the resource management policy including management actions for the resource. | 12-18-2008 |
20090012997 | CMDB-BASED POLICY PROPAGATION - A configuration management database (CMDB) that associates a policy with a configuration item (CI) in the CMDB. The policy contains an “applies to” field and a “type descriptor”. When a relationship is created between the CI and a second CI in the CMDB, the policy is associated with the second CI. | 01-08-2009 |
20090089072 | CONFIGURATION MANAGEMENT DATABASE (CMDB) WHICH ESTABLISHES POLICY ARTIFACTS AND AUTOMATIC TAGGING OF THE SAME - The present invention discloses a solution for managing policy artifacts using a configuration management database (CMDB). Policies can be associated with a number of information technology resources, such as servers, businesses applications and the like. The solution permits automatic tagging of the policies (auto-discovery) as they enter the CMDB. For example, when a policy is added, it can be compared against a set of tagging rules. Multiple rules can match a new policy, which results in multiple tags being added for the policy. The policy specific tags can be optionally indexed for faster searching. Once indexed, the CMDB can support policy and policy tag based queries. In one embodiment, policy artifacts can be manipulated within a CMDB tool in a manner consistent with how the CMDB tool handles configuration items (CIs). | 04-02-2009 |
20090172536 | Providing Run Book Automation Via Manual and Automatic Web-Based Procedures - Providing run book and web user interface automation via and manual and automatic web-based procedures. An application engages a teaching mode in a web-based graphical user interface (GUI), wherein a collection of selectable portions of the web-based GUI is accentuated. The application records a sequence of selections made among the collection of selectable portions of the web-based GUI as well as data entered within the GUI, where the sequence of selections represent a repeatable user-defined procedure for interacting with the web-based GUI. The application replays the sequence of selections with the web-based GUI. | 07-02-2009 |
20110145790 | DEPLOYMENT AND DEPLOYMENT PLANNING AS A SERVICE - A system and method of deploying software provides for comparing a current software topology of a deployment site to a software deployment topology of an application, wherein the software deployment topology is required to deploy the application. One or more mismatches between the current software topology and the software deployment topology may be identified. | 06-16-2011 |
20120203908 | HYBRID CLOUD INTEGRATOR PLUG-IN COMPONENTS - Integrating data processing resources across a hybrid cloud includes providing a plug-in software component configured to be installed in a software framework. When the plug-in software component is activated, it may generate an interface for a consumer of data processing resources. Using this interface, the consumer of data processing resources may request the use of data processing resources provided as a service on the hybrid cloud. In response, the plug-in software component may acquire the requested data processing resources via interfaces provided by the various data processing resources. A number of different data processing resources may have different interface requirements. However, the first interface generated by the plug-in software component may provide a single vendor neutral interface for accessing data processing resources on the hybrid cloud by the consumer of data processing resources. | 08-09-2012 |
20120204169 | HYBRID CLOUD INTEGRATOR - A hybrid cloud integrator provides a capability for integrating data processing resources provided as services across a hybrid cloud. The hybrid cloud integrator includes a software framework that provides for installing, configuring, activating, and controlling operation of a number of plug-in software components. The plug-in software components are configured to provide for using data processing resources provided as a service to process a consumer workload. | 08-09-2012 |
20120204187 | Hybrid Cloud Workload Management - A method, apparatus, and computer program product for managing a workload in a hybrid cloud. It is determined whether first data processing resources processing a portion of a workload are overloaded. Responsive to a determination that the first data processing resources are overloaded, second data processing resources are automatically provisioned and the portion of the workload is automatically moved to the second data processing resources for processing. The second data processing resources are data processing resources that are provided as a service on the hybrid cloud. Processing of a first portion of a workload being processed on first data processing resources of a hybrid cloud are monitored simultaneously with monitoring processing of a second portion of the workload being processed on second data processing resources of the hybrid cloud. The workload may be allocated automatically between the first portion and the second portion responsive to the simultaneous monitoring. | 08-09-2012 |
20120303821 | Programmatic Management of Software Resources in a Content Framework Environment - Methods, systems, and computer program products are disclosed for dynamically integrating software resources (such as web services and other back-end software resources) using the services of a content framework (such as a portal platform). A portlet model is leveraged to allow programmatic portlets to serve as proxies for web services, thereby extending portlets beyond their traditional visual role. A deployment interface and a system interface are described for these portlet proxies. The deployment interface is used for composing new web services, and a composition tool is described. The system interface allows for run-time management of the web services by the portal platform. The service provider for a particular function may be bound to the portlet proxy at development time or at run-time. | 11-29-2012 |
20120317292 | Managing Computer Resources in a Distributed Computing System - Methods, apparatus, and products for managing computer resources in a distributed computing system are disclosed that include registering, in a configuration management database by a discovery module in response to a modification of a resource in a resource container, the resource in association with a configuration management database identifier, the resource characterized by a resource type and a resource identification, the resource container including a manageability endpoint characterized by a manageability endpoint reference; and managing the resource by a management module in dependence upon a resource management policy and the manageability endpoint reference, the resource management policy including management actions for the resource. | 12-13-2012 |
20140006627 | INSTANTIATING RESOURCES OF AN IT-SERVICE | 01-02-2014 |
20140095721 | INSTANTIATING RESOURCES OF AN IT-SERVICE - Instantiating a resource of an IT-service includes: analyzing a service model including nodes representing resources and being indicative of a resource type, each node comprising a generic API providing at least one abstract method for instantiating the resource represented by the respective node. For each node, determining the resource type indicated by the node; evaluating a service provider catalog indicative of a resource manager operable to provide a resource of a given resource type and determining an address of the resource manager; selecting a resource manager; sending a request to the address of the selected resource manager for a description of a resource-manager-specific API of the resource manager; receiving the requested description from the selected resource manager; overriding the abstract method by a resource-manager specific method of the resource-manager-specific API for instantiating the resource; and executing the overridden abstract method for instantiating the resource represented by the node. | 04-03-2014 |
20160072661 | INSTANTIATING RESOURCES OF AN IT-SERVICE - Instantiating a resource of an IT-service includes: analyzing a service model including nodes representing resources and being indicative of a resource type, each node comprising a generic API providing at least one abstract method for instantiating the resource represented by the respective node. For each node, determining the resource type indicated by the node; evaluating a service provider catalog indicative of a resource manager operable to provide a resource of a given resource type and determining an address of the resource manager; selecting a resource manager; sending a request to the address of the selected resource manager for a description of a resource-manager-specific API of the resource manager; receiving the requested description from the selected resource manager; overriding the abstract method by a resource-manager specific method of the resource-manager-specific API for instantiating the resource; and executing the overridden abstract method for instantiating the resource represented by the node. | 03-10-2016 |
David Bruce Lindquist, Raleigh, NC US
Patent application number | Description | Published |
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20110219068 | Flexible Delegation of Management Function For Self-Managing Resources - Included are method, article of manufacture, and device that serve to identify the status of a network resource along with whether the network resource is a self-managing resource. When autonomic management capabilities are identified, an autonomic management rule for management of the network resource may be generated and sent, over a network, for receipt and use by the identified self-managing resource. | 09-08-2011 |
20120173733 | Flexible Delegation of Management Function For Self-Managing Resources - Included are method, article of manufacture, and device that serve to identify the status of a network resource along with whether the network resource is a self-managing resource. When autonomic management capabilities are identified, an autonomic management rule for management of the network resource may be generated and sent, over a network, for receipt and use by the identified self-managing resource. | 07-05-2012 |
Ephraim Lindquist, Terre Haute, IN US
Patent application number | Description | Published |
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20100241475 | Digital Online Exchange - A method of dynamically pricing media content is operatively coupled to one or more clients over a network. The system dynamically adjusts prices of media content and delivers the media content to the clients that order the media content at a dynamically adjusted price. items using a processor based upon the category to which the item is assigned is disclosed. The price can be dynamically adjusted based on profit optimization. Alternatively or additionally, the price can be adjusted based to time between purchases. Further the system is capable or rewarding institutions for allowing members to access the system. | 09-23-2010 |
20100241491 | Dynamic Pricing of Items Based on Estimated Demand For the Item - A method of dynamically adjusting prices of items using a processor based upon the demand for the item based upon offering the item at different prices during different time periods. | 09-23-2010 |
20110082761 | Digital Online Exchange - A system for dynamically pricing media content is operatively coupled to one or more clients over a network. The system dynamically adjusts pricing of the media content and delivers the media content to the clients that order the media content at a dynamically adjusted price. The price can be dynamically adjusted based on profit optimization. Alternatively or additionally, the price can be adjusted based to time between purchases. Further, the system is capable of rewarding institutions for allowing their members to access the system. | 04-07-2011 |
Eric Lindquist, Elmhurst, IL US
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20130240817 | Guardrail System - A guardrail support comprising a base having a first side with attachment holes suitable for attachment to a surface beneath the base using one or more fasteners at a penetrating angle, and a second side one or more attachment holes suitable for attachment to the surface beneath the base using one or more fasteners at a penetrating angle, a post extending vertically from the base, a support member extending at an angle from the first side of the base to the post, where an upper portion of the post is positioned at a distance of between 48 inches and 60 inches from the base, and wherein when the base of the guardrail support is attached to the surface beneath the base, the guardrail support will withstand a 200 pound outward or downward force applied to the upper portion of the post. | 09-19-2013 |
Eric Lindquist, Los Altos, CA US
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20150294460 | METHOD FOR ESTIMATING A QUANTITY OF A BLOOD COMPONENT IN A FLUID CANISTER - A system and method for assessing the concentration of a fluid component within a container, the method comprising: receiving data associated with an image of the canister; from the image, detecting a color grid comprising color elements coupled to the canister,; selecting a region of the image corresponding to a portion of the canister; determining a match between a detected color of the region and a shade in the set of colors associated with the color grid captured in the image; based upon a position of a color element corresponding to the shade in the color grid, retrieving a concentration of the blood component associated with the shade of color. | 10-15-2015 |
Eric P. Lindquist, Menlo Park, CA US
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20120189102 | Ring Gantry Radiation Treatment Delivery System With Dynamically Controllable Inward Extension Of Treatment Head - Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening sufficiently large to accommodate a body of a patient positioned along a longitudinal axis and extending therethrough, and a gantry tilting mechanism configured to tilt the ring gantry to a plurality of different tilt angles relative to the longitudinal axis. A radiation treatment head is coupled to the ring gantry and is rotatable around said central opening in at least a 180 degree arc. The radiation treatment head is mechanically coupled to the ring gantry such that a distance by which the radiation treatment head extends inwardly toward the central opening relative to the ring gantry is dynamically controllable. | 07-26-2012 |
Evan Lindquist US
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20120224070 | Eyeglasses with Integrated Camera for Video Streaming - A camera is integrated into eyeglasses to allow hands-free recording of video or still images. The eyeglasses also include electronic components, such as a processor for encoding the video and a radio for transmitting the video. The eyeglasses may stream the video to a server, where the video may be viewed my other users. The eyeglasses may connect to a cellular data network to stream the data or connect to a nearby mobile device that relays the streaming video to the cellular data network. The size of the eyeglasses with the integrated camera may be reduced by overmolding wiring and/or electronic components into temples of the frame and coupling components with the integrated camera through the temples and the front frame of the eyeglasses. | 09-06-2012 |
George H. Lindquist, Ann Arbor, MI US
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20110307216 | METHOD FOR AUTOMATED MEASUREMENT OF EYE-TRACKING SYSTEM RANDOM ERROR - An estimate of random error in an eye-tracking system is done directly from eye-tracker outputs during a trial, without the need for an explicit calibration process. The distances traveled between adjacent user observations are computed, and the random error δ | 12-15-2011 |
James M. Lindquist, Satellite Beach, FL US
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20120060403 | REPLACEMENT FISHING LINE GUIDE FOR A FISHING POLE - A replacement fishing line guide for a fishing pole. The guide comprises a bendable base; at least a first and a second spaced-apart C-shaped clamp extending upwardly from the base, wherein the fishing pole is received within each of the first and second clamps, each clamp defining an opening therein, a first opening in the first clamp spaced a number of angular degrees from a second opening in the second clamp, a channel defined in a lower region of each of the first and second clamps, the channel for receiving remnant portions of a broken fishing line guide; a connecting segment extending from the base; and a ring attached to the connecting segment for receiving a fishing line within the ring. | 03-15-2012 |
Jeffrey N. Lindquist, Redwood City, CA US
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20140121261 | C-MYC ANTISENSE OLIGONUCLEOTIDES AND METHODS FOR USING THE SAME TO TREAT CELL-PROLIFERATIVE DISORDERS - Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same. | 05-01-2014 |
Jeffrey S. Lindquist US
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20100145437 | Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface - The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields. | 06-10-2010 |
Johan Lindquist, Cape Canaveral, FL US
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20120284804 | SYSTEM AND METHOD FOR PROTECTING DIGITAL CONTENTS WITH DIGITAL RIGHTS MANAGEMENT (DRM) - An approach for protecting digital contents includes a content delivery phase wherein a client stores digital contents or retrieves them in streaming, transmits to a user device the digital content in a protected format along with an enabling code for enabling the user device to access or read the protected digital content. The approach includes a key generation phase in a DRM (Digital Right Management) server which derives at least one key for encrypting the digital contents. A key transmission phase involves the derived key being transmitted from the DRM server to the client. For decrypting the digital content, the user device requests the key from the DRM server, with the request including a key identification defined by the enabling code transmitted by the client to the user device which is used by the DRM server to derive the key for the user device. | 11-08-2012 |
20140068264 | SYSTEM AND METHOD FOR PROTECTING DIGITAL CONTENTS WITH DIGITAL RIGHTS MANAGEMENT (DRM) - An approach for protecting digital contents includes a content delivery phase wherein a client stores digital contents or retrieves them in streaming, transmits to a user device the digital content in a protected format along with an enabling code for enabling the user device to access or read the protected digital content. The approach includes a key generation phase in a DRM (Digital Right Management) server which derives at least one key for encrypting the digital contents. A key transmission phase involves the derived key being transmitted from the DRM server to the client. For decrypting the digital content, the user device requests the key from the DRM server, with the request including a key identification defined by the enabling code transmitted by the client to the user device which is used by the DRM server to derive the key for the user device. | 03-06-2014 |
John Theodore Lindquist, Indianapolis, IN US
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20100086889 | PLIERS FOR FORMING ORTHODONTIC WIRES - A pliers for forming orthodontic wires has opposing beaks with complementary wire-forming surfaces that include interfering portions. A hinge mechanism enables the beaks to open and close by rotating about an axis, and also allows a range of axial motion between the beaks sufficient to prevent interference between the wire-forming surfaces as the beaks are closed. By preventing such interference, novel over-bending capabilities can be achieved to form useful bending of low spring rate wire. A spring, such as a Belleville washer, exerts a biasing force parallel to the hinge axis to maintain alignment of the beaks, but allows the required range of axial motion between the beaks to prevent interference. | 04-08-2010 |
Joseph Daniel Lindquist, Scottsdale, AZ US
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20130073430 | GIFT GIVING SYSTEM AND METHOD - Systems, methods, and computer program products capable of facilitating gift giving are disclosed. The social media contacts of a consumer may be identified. Personal information may be stored for the social media contacts. The consumer may enter gift criteria for the social media contacts, and based on the criteria, it may be determined that a social media contact should receive a gift for a particular occasion. A gift may be automatically purchased and sent to the social media contact on behalf of the consumer. | 03-21-2013 |
Josh Lindquist, Bellevue, WA US
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20120254282 | SYSTEM AND METHOD FOR REPLICATING OFFLINE SCHEDULING TRANSACTIONS FROM A CLIENT TO A SERVER - A facility for replicating offline scheduling transactions directed to a server is provided. The facility is implemented as a client-side application that integrates with and utilizes components of a store-and-forward application, which is operable to execute on a client to guarantee that transactions submitted on the client are replicated and carried out on a service hosted on a remote server even in light of intermittent connectivity between the client, the server, and networks. Records describing transactions intended remote service are written to an outbox of the store-and-forward application on the client. If the item is intended for the scheduling application, the facility is invoked by the store-and-forward application to send the item to the scheduling application. Otherwise, the facility returns the item to the outbox for processing by other components of the store-and-forward application. | 10-04-2012 |
Martin Lindquist, Baltimore, MD US
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20160054409 | FMRI-BASED NEUROLOGIC SIGNATURE OF PHYSICAL PAIN - Described herein is a novel fMRI-based neurologic signature that predicts pain. Further described are methods for detecting pain, for diagnosing pain-related neuropathic conditions and for predicting or evaluating efficacy of an analgesic based on the neurologic signature. | 02-25-2016 |
Michael K. Lindquist, Saint Joseph, MI US
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20130160215 | DOOR WASH AID DISPENSER FOR A LAUNDRY TREATING APPLIANCE - A laundry treating appliance may include a door supporting a wash aid dispenser. The door may be mounted for movement relative to a treating chamber and include a projection extending from a lower portion of the door on a side of the door facing the treating chamber. A wash aid receptacle for holding wash aid chemistry may be provided on the projection for dispensing of the wash aid chemistry into the treating chamber. | 06-27-2013 |
20130160501 | LAUNDRY TREATING APPLIANCE DOOR WITH PLANAR WINDOW ELEMENT AND BAFFLE FOR CONTROLLING LAUNDRY MOVEMENT - A laundry treating appliance may include a tub and a rotatable drum defining a first access opening to the drum, a cabinet including a front wall having a second access opening aligned with the first access opening, a bellows extending between the front wall and the tub to form a fluid seal between the first and second access openings, and the bellows having a compliance portion to accommodate relative movement between the tub and the front wall, and a door movably mounted to the front wall having a planar window element and a projection extending from the planar window element, the projection having at least a portion overlying the compliance portion to retard an item of laundry from entering the compliance portion during rotation of the drum. | 06-27-2013 |
20130276322 | LAUNDRY TREATING APPLIANCE DOOR WITH PLANAR WINDOW ELEMENT AND PROJECTION - A laundry treating appliance treats a laundry load according to at least one cycle of operation. A rotatable drum defines a treating chamber and includes an open face through which access is provided to the treating chamber. An air system supplies air to and exhausts air from the treating chamber and includes an airflow portal adjacent the open face and in fluid communication with the treating chamber. A door includes a panel with a flat surface, the door selectively movable to prevent access through the open face, and the flat surface facing the treating chamber when the door closes the open face. A deflector extends away from the flat surface and at least partially overlies the airflow portal when the door closes the open face. The deflector deflects items in the laundry load away from the airflow portal when the door is closed. | 10-24-2013 |
Rob W. Lindquist, De Pere, WI US
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20080236995 | BURSTING APPARATUS AND METHOD - A method of operating an inserter with infeed and outfeed each driven by a separate servo motor. A controller independently energizes the servo motors to drive the infeed and outfeed to position a continuous feed of objects with a first object in the outfeed and a web between the first and second objects within a bursting space. The outfeed exerts tension on the continuous feed when the web is within the bursting gap. The web is burst and the first object is ejected from the outfeed into an item on a production line. An inserter with separate servo motors driving the infeed and the outfeed to position objects of a continuous feed, to burst webs between the objects by generating tension in the webs and to eject the burst objects from the inserter. | 10-02-2008 |
Rob W. Lindquist, Depere, WI US
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20140331604 | FLEXIBLE LOOP APPLICATOR AND METHOD - A tag applicator, and a method, for applying a tag, having an elastic loop, to a product. The tag applicator includes a linear actuator, and a pair of tag arms, one end of each being pivotably connected to the linear actuator. The two arms are biased toward each other, such as by a spring. A separator is positioned between the tag arms, so as to force the tag arms to separate as the linear actuator extends. A finger or tag hook is connected at the end of each tag arm, configured and positioned to connect to or insert into the elastic loop, and to extend the elastic loop as the tag arms are separated. With the tag loop held open, the product moves into the loop, and the tag is thereby applied to the product. | 11-13-2014 |
Scott Lindquist, Huntington, NY US
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20120134604 | Fries and Condiment Holder - The fries and condiment holder is a combination of two open containers. The larger of the two open containers provides the user with a place to store a food item found at fast food restaurants such as French fries. The smaller of the two open containers is attached to the larger container by a nontoxic adhesive because the present invention makes contact with edible food. The smaller container provides the user with a place to store a condiment. The smaller container is also collapsible and can be flushed into larger container. The user obtains the present invention with the food item in the larger container and with the small container collapse. The user can choose to expand and fill the smaller container with a condiment if the user wants to dip his/her food item in the condiment. | 05-31-2012 |
Sherrill F. Lindquist, Niveville, FL US
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20100178632 | Injection Distraction Device - A system for mitigating pain in a patient associated with needle penetration in the administration of medication, and in particular to a vibratory device configured to be utilized with a variety of existing hand-held intra-oral dental drills or like devices. The preferred embodiment of the present invention teaches a disposable or non-disposable vibratory tip formed to engage an off-the-shelf intra-oral dental drill, the vibratory tip utilizing an off-axis weight associated with a shaft drive engaging the dental drill, to provide a vibratory sensation to an application tip, the application tip configured to engage an area of a patient's mouth targeted for the subsequent needled administration of local anesthetic, or other medication. In use, the application tip is applied to the patient, the dental drill is engaged to rotate the shaft drive of the vibratory tip, vibrating same for period of time, so as to decrease the sensation of pain associated with the subsequent needle penetration. | 07-15-2010 |
Sherrill F. Lindquist, Melbourne, FL US
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20090082839 | Electronic anti-snoring and sleep apnea device for sleep-breathing disorders, electronic anti-bruxing device, and electronic device for TMD therapy - Devices and methods for preventing or mitigating the occurrence of sleep breathing disorders use an extra-oral unit for detecting sounds from a sleeping patient and for sending commands to an intra-oral device for applying an electrical stimulation to one or more locations in the oral cavity of the patient. Similarly, bruxing and temporomandibular disorder can be mitigated or prevented by applying electrical stimulation to the oral cavity of a patient in response to the detection of pressure caused by bruxing activity or oral para-functional activity. The intra-oral unit includes a controller for controlling the generation of the electrical stimulation to be applied to the oral cavity of the patient, and first and second protective layers sealing the controller therebetween. | 03-26-2009 |
20100185254 | ELECTRONIC CONTINUOUS OR PERIODIC AIRWAY THERAPY (ECAT) FOR SLEEP -BREATHING DISORDERS - The intra-oral electronic therapy device includes a substrate to be positioned in a patient's mouth, a rechargeable battery carried by the substrate, and at least one hamular notch tissue contact electrode extending outwardly from the substrate to contact at least one hamular notch in the patient's mouth. A controller is carried by the substrate and cooperates with the rechargeable battery and the hamular notch tissue contact electrode to provide a predetermined electrical stimulation pattern to a hamular notch in the patient's mouth. A programming interface is carried by the substrate and coupled to the controller to permit programming of the predetermined stimulation pattern therein. | 07-22-2010 |
20100200158 | METHODS FOR MAKING INTRA-ORAL ELECTRONIC THERAPY DEVICES FOR TREATING SLEEP-BREATHING DISORDERS, BRUXING DISORDERS, AND TMJ DISORDERS - The method for making an intra-oral electronic therapy device includes thermoforming a first thermoplastic layer on a patient's dental cast, e.g. as received from a patient's dentist, positioning components on the first thermoplastic layer, and thermoforming a second thermoplastic layer on the first thermoplastic layer to define a substrate with the components therein. The components include a rechargeable battery, at least one tissue contact electrode extending outwardly from the substrate to contact at least one tissue area in the patient's mouth, and a controller to cooperate with the rechargeable battery and the at least one tissue contact electrode to provide an electrical stimulation to the at least one tissue area in the patient's mouth. The method includes separating the substrate with the components therein from the dental cast. | 08-12-2010 |
20100204614 | ELECTRONIC SNORE RECORDING DEVICE AND ASSOCIATED METHODS - The snore recording device includes a portable housing, a microphone carried by the housing for capturing an audio input signal including snoring, a memory, such as a removable memory, carried by the housing, and processing circuitry carried by the housing and coupled to the microphone and the memory. The processing circuitry is for low pass filtering the audio input signal from the microphone to generate a low pass filtered analog signal, performing analog-to-digital conversion (ADC) on the low pass filtered analog signal to generate an intermediate digital signal, performing a moving average filtering of the intermediate digital signal to generate moving average intensity data, performing a Fast Fourier Transform (FFT) on the intermediate digital signal to generate frequency component data, and storing at least the moving average intensity data and frequency component data in the memory. | 08-12-2010 |
20100204747 | INTRA-ORAL ELECTRONIC THERAPY DEVICES FOR TREATMENT OF SLEEP-BREATHING DISORDERS, BRUXING DISORDERS, AND TMJ DISORDERS, AND ASSOCIATED METHODS - The intra-oral electronic therapy device includes a substrate to be positioned in a patient's mouth, a rechargeable battery carried by the substrate, and at least one tissue contact electrode, e.g. a hamular notch contact electrode, extending outwardly from the substrate to contact at least one tissue area in the patient's mouth. A controller is carried by the substrate and cooperates with the rechargeable battery and the at least one tissue contact electrode to provide an electrical stimulation to the at least one tissue area in the patient's mouth. The substrate includes first and second thermoplastic layers sealing therebetween the rechargeable battery and controller. | 08-12-2010 |
Stephanie Baker Lindquist, Wilmington, NC US
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20100124307 | APPARATUS AND METHOD FOR MEASURING AND SETTING PERPENDICULARITY OF AN UPPER TIE PLATE OF A NUCLEAR FUEL BUNDLE - An apparatus for measuring perpendicularity of an upper tie plate of a nuclear fuel bundle includes a first comb having a first plurality of teeth; a second comb having a second plurality of teeth, the second comb being parallel to and spaced from the first comb; a comb connector that connects the first comb to the second comb, the comb connector having a second end extending beyond the first comb; a rigid finger provided at the second end of the comb connector; a rotatable gage provided on the second comb; and a mobile finger operatively connected to the gage. | 05-20-2010 |
Stuart Lindquist, Indian Land, SC US
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20130072983 | TETHER CLAMP AND IMPLANTATION SYSTEM - A clamp housing assembly and method for providing stabilization as a bone anchor during an operation. The assembly includes a housing, a locking element and a band. The housing defines a longitudinal axis, a center recess, and at least one slot. The housing has two opposing arms extending from a base. At least a portion of the inside surface of each arm may be threaded and at least a portion of the outside surface of each arm may be planar. The locking element is positionable within the recess in a co-axial relationship to the housing. The band is sized for travel along a predetermined path defined in part by the at least one slot in the housing. | 03-21-2013 |
Stuart Lindquist, Waxhaw, NC US
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20150173805 | SYSTEMS FOR AND METHODS OF FUSING A SACROILIAC JOINT - A sacroiliac joint fusion system including a joint implant, anchor element and delivery tool. The joint implant includes a bore extending non-parallel to the implant longitudinal axis. The anchor element is for receiving in the bore. The delivery tool includes an implant arm and anchor arm. The implant arm distal end is releasably coupled to the joint implant proximal end so the implant arm longitudinal axis is coaxial or parallel with the implant body longitudinal axis. An anchor arm distal end is engaged to the anchor element proximal end. The anchor arm is coupled to the implant arm such that the anchor element longitudinal axis is coaxially aligned with the bore longitudinal axis when the implant arm distal end is releasably coupled with the implant proximal end and the anchor arm distal end is engaged with the anchor element proximal end. | 06-25-2015 |
Stuart Lindquist, Charlotte, NC US
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20150351817 | TETHER CLAMP AND IMPLANTATION SYSTEM - A clamp housing assembly and method for providing stabilization as a bone anchor during an operation. The assembly includes a housing, a locking element and a band. The housing defines a longitudinal axis, a center recess, and at least one slot. The housing has two opposing arms extending from a base. At least a portion of the inside surface of each arm may be threaded and at least a portion of the outside surface of each arm may be planar. The locking element is positionable within the recess in a co-axial relationship to the housing. The band is sized for travel along a predetermined path defined in part by the at least one slot in the housing. | 12-10-2015 |
Susan Lindquist, Cambridge, MA US
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20140273074 | YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE - Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes. | 09-18-2014 |
20140315214 | CHAPERONE INTERACTION ASSAYS AND USES THEREOF - In some aspects, the invention provides methods of identifying, detecting, and/or measuring protein-protein interactions. In some aspects, the invention provides methods of identifying and/or characterizing modulators of protein-protein interactions. In some aspects, the invention provides methods of identifying and/or characterizing modulators of protein activity, wherein the methods are based at least in part on measuring interaction between a chaperone and client protein. In some aspects, the invention provides methods for identifying and/or characterizing compounds and/or for assessing compound specificity, wherein the methods are based at least in part on measuring interaction between a chaperone and client protein. In some embodiments, a client protein is a kinase. In some embodiments, a compound is a kinase inhibitor. In some aspects, the invention provides methods of profiling kinase inhibitor specificity. In some aspects, the invention provides assay systems and/or reagents useful for performing one or more of the inventive methods. In some aspects, the invention provides newly identified targets of a variety of kinase inhibitors. In some aspect, the invention provides methods of inhibiting kinases identified herein as targets of certain kinase inhibitors. In some aspects, the invention provides methods of treating a disease, e.g., cancer, by inhibiting one or more kinase(s) newly identified as targets of certain kinase inhibitors. | 10-23-2014 |
Susan Lindquist, Chestnut Hill, MA US
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20090194317 | Electrical Conductors and Devices from Prion-Like Proteins - The present invention provides novel polypeptides comprising a prion-aggregation domain and a second domain; novel polynucleotides encoding such polypeptides; host cells transformed or transfected with such polynucleotides; novel fibrils with specific functionalities and unusually high chemical and thermal stability; and methods of making and using the foregoing. | 08-06-2009 |
20090280480 | Devices from Prion-Like Proteins - The present invention provides novel polypeptides comprising a prion-aggregation domain and a second domain; novel polynucleotides encoding such polypeptides; host cells transformed or transfected with such polynucleotides; novel fibrils with specific functionalities and unusually high chemical and thermal stability; and methods of making and using the foregoing in, for example, the production of nanoscale devices. | 11-12-2009 |
20110183860 | Protein Aggregation Domains and Methods of Use Thereof - Using the Sup35 prion proteins of two distantly related yeast species, it is established that prion replication is initiated by small elements of primary sequence, which can be identified using arrays of short peptides. Subtle differences in replication elements govern the formation of distinct aggregate conformations (prion strains) and also determine their species-specific seeding activities. A Sup35 chimera that promiscuously forms prions in more than one species does so by virtue of carrying the replication element of each species. Mutations or conditions that cause the chimera to assemble into distinct prion strains favor recognition of distinct replication elements. Therefore, subtle differences in small sequences that constitute prion replication elements encode important determinants of prion propagation and transmission. The protein aggregation domains, methods for identification thereof, and polypeptides and higher order aggregates including the protein interaction domains, as well as arrays including peptides derived from an aggregation-prone polypeptide are provided. | 07-28-2011 |
20110300533 | Yeast Screens for Treatment of Human Disease - Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes. | 12-08-2011 |
20120135435 | Methods for Identifying Factors That Control the Folding of Amyloid Proteins of Diverse Origin - The present invention provides a yeast cell based system for determining factors that control the folding of amyloid proteins of diverse origins. Further the present invention provides methods of using such a system to screen for reagents that affect amyloid formation, a process that is integral to several devastating human disease including Creutzfeld-Jacob disease (CJD), fatal familial insomnia (FFI), Gertsmann-Straussler-Scheinker (GSS) syndrome, and kuru. The system of the present invention provides a rapid screening system to quickly and cheaply identify reagents that affect the folding and aggregation properties of the target protein. | 05-31-2012 |
20120190566 | COMPOSITIONS AND METHODS FOR INHIBITING BIOFILMS - Using arrays of peptides derived from | 07-26-2012 |
20120301433 | BACTERIOPHAGES EXPRESSING AMYLOID PEPTIDES AND USES THEREOF - The present invention generally relates to engineered bacteriophages which express amyloid peptides for the modulation (e.g. increase or decrease) of protein aggregates and amyloid formation. In some embodiments, the engineered bacteriophages express anti-amyloid peptides for inhibiting protein aggregation and amyloid formation, which can be useful in the treatment and prevention of and bacterial infections and biofilms. In some embodiments, the engineered bacteriophages express amyloid peptides for promoting amyloid formation, which are useful for increasing amyloid formation such as promoting bacterial biofilms. Other aspects relate to methods to inhibit bacteria biofilms, and methods for the treatment of amyloid related disorders, e.g., Alzheimer's disease using an anti-amyloid peptide engineered bacteriophages. Other aspects of the invention relate to engineered bacteriophages to express the amyloid peptides on the bacteriophage surface and/or secrete the amyloid peptides, e.g., anti-amyloid peptides and pro-amyloid peptides, and uses thereof for modulation protein aggregates and amyloid formation. | 11-29-2012 |
20130005608 | YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE - Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes. | 01-03-2013 |
20140234858 | HSF1 AS A MARKER IN TUMOR PROGNOSIS AND TREATMENT - In some aspects, the invention relates to Heat Shock Protein-1 (HSF1) gene and HSF1 gene products. In some aspects, the invention provides methods of tumor diagnosis, prognosis, treatment-specific prediction, or treatment selection, the methods comprising assessing the level of HSF1 expression or HSF1 activation in a sample obtained from the tumor. In some aspects, the invention relates to the discovery that increased HSF1 expression and increased HSF1 activation correlate with poor outcome in cancer, e.g., breast cancer. | 08-21-2014 |
20150241436 | HSF1 AND HSF1 CANCER SIGNATURE SET GENES AND USES RELATING THERETO - In some aspects, the invention relates to Heat Shock Protein-1 (HSF1) gene and HSF1 gene products. In some aspects, the invention provides methods of tumor diagnosis, prognosis, treatment-specific prediction, or treatment selection, the methods comprising assessing the level of HSF1 expression or HSF1 activation in a sample obtained from the tumor. In some aspects, the invention relates to the discovery that increased HSF1 expression and increased HSF1 activation correlate with poor outcome in cancer, e.g., breast cancer. In some aspects, the invention relates to the HSF1 cancer program genes, HSF1 cancer signature set genes, subsets thereof, and uses in tumor diagnosis, prognosis, treatment-specific prediction, treatment selection, or drug discovery, among others. | 08-27-2015 |
Thomas Lindquist, Ballico, CA US
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20130087570 | METHOD FOR PROVIDING AND TESTING STORAGE CONTAINMENT - In various embodiments, systems and methods are provided for constructing and testing of a barrier providing secondary containment for aboveground storage tanks. Concrete storage containers can be manufactured with primary steel tanks and spill containment formed using an airtight tank wrap. Concrete storage containers can be manufactured with a barrier providing secondary containment to meet or exceed most current codes and standards commonly required for the storage of petroleum, flammable, combustible and other hazardous liquids. Such storage containers can include one or more thermal barriers that provide enhanced resistance when subjected to liquid-pool/furnace fire tests. Additionally, a concrete exterior acts as a thermal mass reducing temperature variations. The concrete exterior further provides a non-corrosive, durable exterior having increased vehicle-impact and projectile-impact resistance. Due to the method of construction in some embodiments, concrete storage containers are provided which give thermal/vehicle impact/projectile resistance while also meeting expectations in weight and buoyancy criteria. | 04-11-2013 |
Wesley D. Lindquist, Kansas City, MO US
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20140003034 | LIGHT ANIMATED OBJECTS | 01-02-2014 |
20160047536 | LIGHT ANIMATED OBJECTS - Embodiments of the present invention use light to add human-like features to an inanimate object. In one embodiment, the object includes a film with an image that has been manipulated to provide for a low profile projection of an image onto a vertical surface directly adjacent to the object. For example, the image of a witch's head could be projected onto a wall and directly beneath, a witch's hat could be hanging on the wall. In another embodiment, changing lights and shadows are used to create animated objects out of otherwise inanimate objects. Various embodiments include components to create the illusion of changing facial expressions. These components include a plurality of light sources and an electronic device that controls the light sources to create the animation. | 02-18-2016 |
William B. Lindquist, Rio Rancho, NM US
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20130283381 | SYSTEMS AND METHODS FOR PROVIDING ANTI-MALWARE PROTECTION ON STORAGE DEVICES - Systems and methods for providing anti-malware protection on storage devices are described. In one embodiment, a storage device includes a controller, firmware, and memory. The firmware communicates with an authorized entity (e.g., external entity, operating system) to establish a secure communication channel. The system includes secure storage to securely store data. | 10-24-2013 |