Lindenstruth
Kai Lindenstruth, Loerrach DE
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20080214561 | SOLID FORMS OF [4-(3-FLUORO-5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-PIPERAZIN-1-YL-[5-METHANESULFONYL-2-((S)-2,2,2-TRIFLUORO-1-METHYL-ETHOXY)-PHENYL]-METHANONE - The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease. | 09-04-2008 |
20100311971 | SOLID FORMS OF [4-(3-FLUORO-5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-PIPERAZIN-1-YL-[5-METHANESUL- FONYL-2-((S)-2,2,2-TRIFLUORO-1-METHYL-ETHOXY)-PHENYL]-METHANONE - The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease. | 12-09-2010 |
20110295007 | SOLID FORMS OF [4-(3-FLUORO-5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-PIPERAZIN-1-YL-[5-METHANESUL- FONYL-2-((S)-2,2,2-TRIFLUORO-1-METHYL-ETHOXY)-PHENYL]-METHANONE - The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease. | 12-01-2011 |
20120039999 | PHARMACEUTICAL COMPOSITIONS OF METABOTROPIC GLUTAMATE 5 RECEPTOR (MGLU5) ANTAGONISTS - Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The compositions contain the therapeutic active compound with non-ionic polymer and ionic polymer, binder and fillers in either matrix pellet, matrix tablet or coated pellets. The compositions provide a pH-independent in vitro release profile with NMT 70% in one hour, NMT 85% in 4 hour, and NLT 80% in 8 hours. The compositions are useful for the treatment of CNS disorders, such as Treatment-Resistant Depression (TRD) and Fragile X Syndrome. | 02-16-2012 |
20120040008 | PHARMACEUTICAL COMPOSITIONS OF METABOTROPIC GLUTAMATE 5 RECEPTOR (MGLU5) ANTAGONISTS - Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The compositions contain the therapeutic active compound with non-ionic polymer and ionic polymer, binder and fillers in either matrix pellet, matrix tablet or coated pellets. The compositions provide a pH-independent in vitro release profile with NMT 70% in one hour, NMT 85% in 4 hour, and NLT 80% in 8 hours. The compositions are useful for the treatment of CNS disorders, such as Treatment-Resistant Depression (TRD) and Fragile X Syndrome. | 02-16-2012 |
20120309969 | SOLID FORMS OF [4-(3-FLUORO-5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-PIPERAZIN-1-YL-[5-METHANESUL- FONYL-2-((S)-2,2,2-TRIFLUORO-1-METHYL-ETHOXY)-PHENYL]-METHANONE - The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease. | 12-06-2012 |
Kai Lindenstruth, Berlin DE
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20120114751 | PHARMACEUTICAL COMPOSITION FOR TREATING HCV INFECTIONS - The present invention relates to a granular pharmaceutical composition comprising an HCV protease inhibitor and at least one poloxamer. | 05-10-2012 |
20130197225 | New Solid Forms of [4-(3-Fluoro-5-Trifluoromethyl-Pyridin-2-Yl)-Piperazin-1-Yl-[5-Methanesul- fonyl-2-((S)-2,2,2-Trifluoro-1-Methyl-Ethoxy)-Phenyl]Methanone - The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease. | 08-01-2013 |
20130331314 | PHARMACEUTICAL COMPOSITION FOR TREATING HCV INFECTIONS - The present invention relates to a granular pharmaceutical composition comprising an HCV protease inhibitor and at least one poloxamer. | 12-12-2013 |
Lars Lindenstruth, Wetzlar DE
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20130257366 | COMB-STRUCTURED SHIELDING LAYER AND WIRELESS CHARGING TRANSMITTER THEREOF - A comb-structured shielding layer and a wireless charging transmitter thereof are provided. The wireless charging module is connected to a power source, has at least one wireless charging coil and at least one comb-structured shielding layer, and is configured to convert alternative current power from the power source to H-field electromagnetic radiations, and wirelessly charges an electronic device. The comb-structured shielding layer is disposed between the wireless charging module and the target electronic device and configured to allow the H-field electromagnetic radiations pass through. The comb-structured shielding layer includes a first area and a second area. The first area is electrically connected to a reference electric potential. The second area is electrically connected to the reference electric potential through the first area, and is configured to shield the E-field electromagnetic radiations but allow the H-field electromagnetic radiations pass through the comb-structured shielding layer. | 10-03-2013 |
20140197782 | WIRELESS CHARGER WITH COMBINED ELECTRIC RADIATION SHIELDING AND CAPACITIVE SENSING FUNCTIONS - A wireless charger with combined electric radiation shielding and capacitive sensing functions is provided. The wireless charger comprises a charging module, a capacitive sensor, and a control unit. The charging module comprises a first coil, a placing area, and a comb-shaped shielding located between the placing area and the first coil. The capacitive sensor is connected to the comb-shaped shielding to detect the capacitance varient between the comb-shaped shielding and the environment. When the wireless charger is in a standby mode, the comb-shaped shielding is for sensing capacitance. When the capacitance varient exceeds a predefined threshold and an electronic device for wireless charging is placed on the placing area, the control unit switches the wireless charger to a charging mode and the comb-shaped shielding is for electric radiation shielding. | 07-17-2014 |
Michael Lindenstruth, Gross-Gerau DE
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20100211263 | LEARNING CONTROLLER FOR THE COMPENSATION OF TORQUE PULSATIONS IN A STEERING ASSEMBLY - A control device for controlling an electric steering assembly is provided to reduce torque pulsations in the steering assembly. The control device comprises a learning control device for the suppression of periodic disturbances in a steering assembly. The learning control device is referred to as POISON (periodic on-line iterative signal optimum navigation) controller. By iterative learning of a corrected reference signal the POISON controller is able to compensate for control errors which occur in conventional closed loop control systems. The POISON controller is capable of permanent online operation. Therefore it is able to compensate for certain changes in the controlled system. The POISON controller can easily be added to existing power steering control loops. | 08-19-2010 |
20110125450 | DIGITAL CONTROLLER FOR AN AUTOMOTIVE STEERING TEST RIG - A digital control system for performing a durability test with a steering test rig is disclosed. The digital control system comprises a learning control device for controlling periodic reference signals in servo actuator systems, such as hydraulic cylinders and electrical motors. This learning device is referred to as POISON (periodic on-line iterative signal optimum navigation) controller. By iterative learning of a corrected reference signal, the POISON controller is able to compensate for control errors which occur in conventional closed loop control systems. In contrast to existing control systems, the POISON controller is capable of permanent online operation. Therefore it is able to compensate for certain changes in the controlled system. The POISON controller can easily be added to existing servo control loops. | 05-26-2011 |
Volker Lindenstruth, Mainz DE
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20110220324 | BUILDING FOR A COMPUTER CENTRE WITH DEVICES FOR EFFICIENT COOLING - The invention relates to a structure of a multi-storey computer centre building which is suitable for accommodating a multiplicity of racks ( | 09-15-2011 |
20140209272 | Mobile Data Centre Unit With Efficient Cooling Means - The present disclosure relates to a mobile data centre unit, which is adapted to house at least one rackbeing designed to provide storage space for electronic equipment. The mobile data centre unit is equipped with passive cooling means in order to provide dissipation of heat being generated by the electronic equipment. | 07-31-2014 |
20150083363 | METHOD FOR OPERATING A DATA CENTRE WITH EFFICIENT COOLING MEANS - The present invention relates to a method for operating a data centre, which is adapted to house a multiplicity/plurality of racks being designed to provide storage space for IT equipment. The data centre is equipped with cooling means in order to provide dissipation of heat being generated by the IT equipment. | 03-26-2015 |