Patent application number | Description | Published |
20120078521 | APPARATUS, SYSTEM AND METHODS FOR ASSESSING DRUG EFFICACY USING HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes a computer-implemented method for assessing drug efficacy, comprising: accessing a first data set related to the performance of a target drug for a given indication; accessing a second data set related to a control for the indication; comparing the data for the target drug and the data for the control on at least one of a plurality of different metrics using a holistic analysis, wherein the at least one metric corresponds to an outcome associated with the indication and generating a corresponding report. An example apparatus/system includes a holistic analysis and viewing system to support the assessment of drug efficacy, said system comprising: a standardizer to at least one of standardize and normalize data related to drug development; a deviation analyzer to analyze said data based on at least one of a plurality of different efficacy metrics, wherein a quantified variation between a first data set of results corresponding to an identified target drug and a second data set of results corresponding to a control, wherein said first data set of results is provided for comparison with the second data set of results and the deviation therebetween is compared to the at least one efficacy metric. | 03-29-2012 |
20120078522 | SYSTEMS AND METHODS FOR HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes accessing data related to drug development; pre-processing the data to prepare the data for measurement and analysis; and analyzing the data based on at least one of a plurality of different metrics. Each metric corresponds to a quantified variation between a first data set of results corresponding to a category in the drug development process. The first data set of results is provided for comparison with a second data set of results corresponding to at least one other category in the drug development process. At least some of the plurality of metrics are aggregated to generate a visual representation representing an integrated comparative visualization for the identified category. | 03-29-2012 |
20120078840 | APPARATUS, SYSTEM AND METHODS FOR COMPARING DRUG SAFETY USING HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process, and safety testing. An example method includes providing a first set of data corresponding to a drug of interest; providing a reference set of drug interaction data, comparing the first set of data to the reference set using a holistic analysis, and reporting the results of the comparison. An example of the holistic analysis and viewing apparatus for drug safety comprises a standardizer to at least one of standardize and normalize drug interaction data related to drug safety; a deviation analyzer to compare the drug interaction data to data corresponding to a drug under review using a holistic analysis, and a reporter for reporting the output of the deviation analyzer. | 03-29-2012 |
20130002646 | METHOD AND SYSTEM FOR NAVIGATING, SEGMENTING, AND EXTRACTING A THREE-DIMENSIONAL IMAGE - A method for navigating a three-dimensional (3D) image includes accessing a 3D image dataset, generating a 3D mesh corresponding to a 3D segmentation result using the 3D image dataset, displaying a 3D surface rendering of the 3D surface mesh, and navigating the 3D image based on a manual input received from a user indicated on the rendered 3D mesh. | 01-03-2013 |
20140195170 | APPARATUS, SYSTEM AND METHODS FOR ASSESSING DRUG EFFICACY USING HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes a computer-implemented method for assessing drug efficacy, comprising: accessing a first data set related to the performance of a target drug for a given indication; accessing a second data set related to a control for the indication; comparing the data for the target drug and the data for the control on at least one of a plurality of different metrics using a holistic analysis, wherein the at least one metric corresponds to an outcome associated with the indication and generating a corresponding report. An example apparatus/system includes a holistic analysis and viewing system to support the assessment of drug efficacy, said system comprising: a standardizer to at least one of standardize and normalize data related to drug development; a deviation analyzer to analyze said data based on at least one of a plurality of different efficacy metrics, wherein a quantified variation between a first data set of results corresponding to an identified target drug and a second data set of results corresponding to a control, wherein said first data set of results is provided for comparison with the second data set of results and the deviation therebetween is compared to the at least one efficacy metric. | 07-10-2014 |
Patent application number | Description | Published |
20090290772 | Medical Data Processing and Visualization Technique - A data processing technique is provided. In one embodiment, a computer-implemented method includes accessing patient image and non-image deviation scores derived through respective comparisons of patient image and non-image data to standardized image and non-image data. The method may also include processing the image and non-image deviation scores to generate a visual output indicative of differences between the patient image and non-image data, and the standardized image and non-image data, respectively. Further, the method may include displaying the visual output. Additional methods, systems, and manufactures are also disclosed. | 11-26-2009 |
20090292478 | System and Method for Analysis of Multiple Diseases and Severities - A data processing technique is provided. In one embodiment, a computer-implemented method includes accessing reference deviation maps for a plurality of disease types. The reference deviation maps may include subsets of maps associated with severity levels of respective disease types, and a disease severity score may be associated with each severity level. The method may include selecting patient severity levels for multiple disease types based on the subsets of reference deviation maps. Also, the method may include automatically calculating a combined patient disease severity score based at least in part on the disease severity scores associated with the selected patient severity levels, and may include outputting a report based at least in part on the combined patient disease severity score. Additional methods, systems, and manufactures are also disclosed. | 11-26-2009 |
20090292551 | System and Method for Mapping Structural and Functional Deviations in an Anatomical Region - A data processing technique is provided. In one embodiment, a computer-implemented method includes accessing individual patient deviation maps indicative of a structural difference and a functional difference, respectively, of at least one anatomical region of a patient with respect to standardized reference image data. The method may also include generating a composite patient deviation map indicative of both the structural difference and the functional difference based on at least the individual patient deviation maps, and outputting the composite patient deviation map. Additional methods, systems, and manufactures are also disclosed. | 11-26-2009 |
20090292557 | System and Method for Disease Diagnosis from Patient Structural Deviation Data - A data processing technique is provided. In one embodiment, a computer-implemented method includes accessing patient deviation data of a structural difference between a patient anatomical feature and a standardized anatomical feature. The method may also include comparing the patient deviation data to reference deviation data sets representative of multiple disease types. Each reference deviation data set may be representative of an expected deviation from the standardized anatomical feature for a particular disease type. The method may further include automatically identifying one or more potential patient disease types based at least in part on the comparison. Additional methods, systems, and manufactures are also disclosed. | 11-26-2009 |
Patent application number | Description | Published |
20120078525 | APPARATUS, SYSTEM AND METHODS FOR SELECTING DRUG CANDIDATES USING DISEASE SIGNATURE HOLISTIC ANALYSIS AND PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes providing a first set of data corresponding to a drug of interest: providing a disease signature; providing a reference set of drug interaction data associated with the disease signature, comparing the first set of data to the reference set using a holistic analysis, and reporting the results of the comparison. An example of the apparatus includes, a standardizer to at least one of standardize and normalize drug interaction data related to a pre-selected disease signature: a deviation analyzer to compare the drug interaction data to data corresponding to a drug under review using a holistic analysis, and a reporter for reporting the output of the deviation analyzer. | 03-29-2012 |
20120078526 | APPARATUS, SYSTEM AND METHODS FOR DETERMINING DRUG ATTRIBUTES USING DISEASE SIGNATURE HOLISTIC ANALYSIS AND PHARMACOLOGICAL DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example of the inventive apparatus includes a standardizer to at least one of standardize and normalize data related to drug performance for a known disease signature; and a deviation analyzer to analyze said data based on at least one of a plurality of different efficacy metrics, wherein a quantified variation between a first data set of results corresponding to an identified target drug and a second data set of results corresponding to a control, wherein said first data set of results is provided for comparison with the second data set of results and the deviation therebetween is compared to the at least one efficacy metric associated with the disease signature. | 03-29-2012 |
20120078528 | PATIENT DIAGNOSIS USING DRUG RELATED HOLISTIC DATA - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. A computer-implemented method for integrated comparative holistic analysis of drug development and related quantifiable patient treatment decision support for a medical condition having a known disease signature. | 03-29-2012 |
20120078601 | DRUG TREATMENT PLANS DERIVED FROM HOLISTIC ANALYSIS - Certain examples provide systems and methods for holistic viewing to provide comparative analysis and patient treatment decision support in a drug therapy development process. A computer-implemented method for developing a therapeutic drug treatment plan for a patient using quantifiable comparative holistic decision support. In addition, the inventive may also be summarized as a computer-implemented method for developing a therapeutic drug treatment plan for a patient using quantifiable comparative holistic decision support for a known disease signature corresponding to a subject medical condition of a patient. | 03-29-2012 |
Patent application number | Description | Published |
20100130848 | METHODS AND APPARATUS FOR DETERMINING BRAIN CORTICAL THICKNESS - Methods and apparatus for determining brain cortical thickness. One method includes determining an intensity profile at each of a plurality of cortical surface points of an imaged brain using brain tissue image data and calculating a cortical thickness based on a parametrically determined transition point of each intensity profile. | 05-27-2010 |
20110129129 | SYSTEM AND METHOD FOR INTEGRATED QUANTIFIABLE DETECTION, DIAGNOSIS AND MONITORING OF DISEASE USING POPULATION RELATED DATA FOR DETERMINING A DISEASE SIGNATURE - A system and method for detecting, diagnosing, and monitoring a disease and determining a disease signature including accessing patient deviation scores indicative of differences between patient data and reference data representative of a population segment, the patient deviation scores derived from longitudinal patient data such that the patient deviation scores include a plurality of sets of patient deviation scores, each set indicative of differences between patient data collected at a respective point in time and the reference data. The system and method also includes identifying a trend in the patient deviation scores for at least one clinical parameter, generating a report including a visual indication of the trend, and outputting the report. The report includes one or more views including Z, T, D, DT, and D feedback on T views, using image and non-image data. | 06-02-2011 |
20110129130 | SYSTEM AND METHOD FOR INTEGRATED QUANTIFIABLE DETECTION, DIAGNOSIS AND MONITORING OF DISEASE USING POPULATION RELATED TIME TREND DATA - A system and method for detecting, diagnosing, and monitoring a disease and determining a disease signature including accessing patient deviation scores indicative of differences between patient data and reference data representative of a population segment, the patient deviation scores derived from longitudinal patient data such that the patient deviation scores include a plurality of sets of patient deviation scores, each set indicative of differences between patient data collected at a respective point in time and the reference data. The system and method also includes identifying a trend in the patient deviation scores for at least one clinical parameter, generating a report including a visual indication of the trend, and outputting the report. The report includes one or more views including Z, T, D, DT, and D feedback on T views, using image and non-image data. | 06-02-2011 |
20110129131 | SYSTEM AND METHOD FOR INTEGRATED QUANTIFIABLE DETECTION, DIAGNOSIS AND MONITORING OF DISEASE USING POPULATION RELATED TIME TREND DATA AND DISEASE PROFILES - A system and method for detecting, diagnosing, and monitoring a disease and determining a disease signature including accessing patient deviation scores indicative of differences between patient data and reference data representative of a population segment, the patient deviation scores derived from longitudinal patient data such that the patient deviation scores include a plurality of sets of patient deviation scores, each set indicative of differences between patient data collected at a respective point in time and the reference data. The system and method also includes identifying a trend in the patient deviation scores for at least one clinical parameter, generating a report including a visual indication of the trend, and outputting the report. The report includes one or more views including Z, T, D, DT, and D feedback on T views, using image and non-image data. | 06-02-2011 |
20110218405 | SYSTEM AND METHOD FOR INTEGRATED QUANTIFIABLE DETECTION, DIAGNOSIS AND MONITORING OF DISEASE USING PATIENT RELATED TIME TREND DATA - A system comprising a memory device having a plurality of routines stored therein, a processor configured to execute the plurality of routines stored in the memory device, the plurality of routines comprising: a routine configured to effect, when executed, accessing of patient deviation scores indicative of differences between patient data and reference data representative of a population segment, wherein the patient deviation scores are derived from longitudinal data of the patient data such that the patient deviation scores include a plurality of sets of patient deviation scores, each set indicative of differences between patient data collected at a respective point in time and the reference data; a routine configured to effect, when executed, identifying a trend in the patient deviation scores for at least one clinical parameter; a routine configured to effect, when executed, generating of a report including a visual indication of the trend; and a routine configured to effect, when executed, outputting of the report. The report includes one or more views including Z, T, D, DT, and D feedback on T views, using image and non-image data. | 09-08-2011 |