Lieu, CA
Daryl Lieu, Menlo Park, CA US
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20110055307 | METHOD FOR FLOATING POINT ROUND TO INTEGER OPERATION - An apparatus and method for computing a rounded floating point number. A floating point unit (FPU) receives an instruction to round a floating point number to a nearest integral value and retrieves a binary source operand having an exponent of a fixed first number of bits and a mantissa of a fixed second number of bits. If the unbiased exponent value is greater than or equal to zero and less than the fixed second number, the FPU generates a mask having N consecutive ‘1’ bits beginning with the least significant bit and whose remaining bits have a value of ‘0’, where N is equal to the fixed second number minus the unbiased exponent value. The FPU computes a bitwise OR of the source operand with the mask, increments the result if the instruction is to round up, and computes a bitwise AND of the result with the inverse of the mask. | 03-03-2011 |
Daryl Lieu, Sunnyvale, CA US
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20100318772 | SUPERSCALAR REGISTER-RENAMING FOR A STACK-ADDRESSED ARCHITECTURE - A system and method for increasing processor throughput by decreasing a loop critical path. In one embodiment, a table comprises multiple stack entries, each comprising an x87 floating-point (FP) stack specifier. The combinatorial logic for operand translation of N FP instructions per clock cycle may require N instantiated copies of a combinatorial logic block. Each instantiated copy may determine a new ordering of the stack entries. Control logic may receive necessary information from the corresponding N FP instructions and determine a corresponding combined computational effect, or stack reordering, on entries within the table based on two or more instructions. Resulting control signals are conveyed to the N instantiated copies. A resulting accumulative delay from an input of the first copy to the output of the Nth copy may be less than or equal to (N−1)*time_delay versus a longer N*time_delay. | 12-16-2010 |
Deborah Lieu, Davis, CA US
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20140273207 | LABEL-FREE IDENTIFICATION OF STEM CELL-DIFFERENTIATED CELLS - Methods are disclosed for isolation of a stem-cell derived differentiated cell, which method entails illuminating an incident light onto a plurality of stem-cell derived cells that comprise at least an undifferentiated cell and a differentiated cell possessing a noncentrosymmetric structure, wherein the differentiated cell generates second-harmonic light from the incident light; and isolating the differentiated cell identified by the second-harmonic light. Devices for carrying out the methods are also provided. | 09-18-2014 |
Deborah K. Lieu, Davis, CA US
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20120014924 | Compositions and Methods for Improving the Functional Efficacy of Stem Cell-Derived Cardiomyocytes - This invention provides an isolated stem cell modified to provide, enhance or contain the functional characteristics of the sarcoplasmic reticulum (SR) The isolated stem cells are modified by expressing a calcium channel protein, by expressing a calcium pump protein such as the sarcro/endoplasmic reticulum Ca2+-ATPase (SERCA) protein, by inhibiting or downregulating expression of the Na+/Ca2+ exchanger (NCX) protein, by expressing a calcium handling protein, by expressing a transverse (t)-tubule, and/or by expressing a transverse (t)-tubule biogenic protein The modified cells may be expanded to a substantially homogenous population of these cells or differentiated to a more mature cell type Compositions are also provided The cells and compositions can be administered to a host and used to regenerate cardiac tissue, improve cardiac function, restore action potential of cardiac tissue, and treat or prevent cardiac malfunction Use for diagnostic screening of therapeutic candidates is also provided | 01-19-2012 |
20150218549 | ELECTROPHYSIOLOGICALLY MATURE CARDIOMYOCYTES AND METHODS FOR MAKING SAME - Methods to prepare electrophysiology mature cells from immature cells are provided, without the need for genetic manipulation. | 08-06-2015 |
Deborah K. Lieu, Elk Grove, CA US
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20160045555 | Compositions and Methods for Improving the Functional Efficacy of Stem Cell-Derived Cardiomyocytes - An isolated stem cell that has been modified to provide, enhance orcontain the functional characteristics of the sarcoplasmic reticulum (SR). The isolated stem cells are modified in one or more of the following manners: by expressing a calcium channel protein; by expressing a calcium pump protein such as the sarcro/endoplasmic reticulum Ca | 02-18-2016 |
Dinah Lieu, San Diego, CA US
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20160035686 | CHIP ATTACHMENT SYSTEM - Forming the chip attachment system includes obtaining a chip having a bump core on a die. The method also includes obtaining an intermediate structure having a transfer pad on a substrate. The method further includes transferring the transfer pad from the substrate to the bump core such that the transfer pad becomes a solder layer on the bump core. | 02-04-2016 |
Hsiao Lieu, Burlingame, CA US
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20080213165 | Methods and Compositions for Increasing Patent Tolerability During Myocardial Imaging Methods - The present application discloses methods and compositions for increasing patient tolerability during myocardial imaging comprising the administration of doses of caffeine and one or more adenosine A | 09-04-2008 |
20090081120 | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods - The present application discloses methods and compositions for increasing patient tolerability during myocardial imaging comprising the administration of doses of caffeine and one or more adenosine A | 03-26-2009 |
20120178689 | METHODS OF TREATMENT WITH NATRIURETIC PEPTIDES - Methods of treating heart failure, or decreasing blood pressure, comprising administering an NP at an appropriate dose, or in an amount sufficient to provide particular concentrations of NP, are provided. | 07-12-2012 |
20120220528 | SYSTEMS AND METHODS FOR THERAPY OF KIDNEY DISEASE AND/OR HEART FAILURE USING CHIMERIC NATRIURETIC PEPTIDES - Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are based on delivery of a chimeric natriuretic peptide to a patient. Methods for increasing peptide levels include direct peptide delivery via either an external or implantable programmable pump. | 08-30-2012 |
Hsiao D. Lieu, Burlingame, CA US
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20080267861 | Myocardial Perfusion Imaging - This invention relates to methods for performing myocardial perfusion imaging for diagnosing and characterizing coronary artery disease using an intravenous (IV) bolus injection of regadenoson while the patient is undergoing sub-maximal exercise. | 10-30-2008 |
Hsiao Dee Lieu, Burlingame, CA US
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20100158797 | USE OF A2A ADENOSINE RECEPTOR AGONISTS - Myocardial imaging methods that are accomplished by administering doses of a pharmaceutical composition including regadenoson—an adenosine A | 06-24-2010 |
20120189538 | USE OF A2A ADENOSINE RECEPTOR AGONISTS - Myocardial imaging methods that are accomplished by administering doses of a pharmaceutical composition including regadenoson—an adenosine A | 07-26-2012 |
Johan V. Lieu, Santa Monica, CA US
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20090132665 | METHOD AND SYSTEM FOR COMMUNICATING INVITATIONS AND RESPONSES TO AN EVENT WITH A MOBILE DEVICE - The invention provides a communications system comprising an event server computer system, an event creation module on the event server computer system for permitting the creation of an event from an event host computer system over the network, and a storing module on the event server computer system for storing the event on the event server computer system, a transmissions module on the event server computer system for transmitting a signal relating to the event from a first computer system to a second computer system over a network, and a location selection module on the event server computer system for selecting at least one location from the event host computer system and associating the location with the event on the event server computer system. | 05-21-2009 |
Johnson Lieu, San Francisco, CA US
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20160066004 | SYSTEMS AND METHODS FOR TEMPORARY ACCESS TO MEDIA CONTENT - Methods, systems, and/or devices for providing temporary access to media content are described herein. In one aspect, a server provides authorization to a transportation service provider for accessing one or more media items associated with an account of a user for a media content provider. The server provides the authorization in response to the user reserving a vehicle through the transportation service provider. Additionally, the server receives a first request (e.g., a request initiated by a mobile device of the user) to present a first media item of the one or more media items at a media presentation system of a reserved vehicle provided by the transportation service provider. In accordance with the authorization, the server sends a portion of the first media item for presentation at the media presentation system. | 03-03-2016 |
Pauline Lieu, San Diego, CA US
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20080216185 | Compositions and Methods for Genetic Manipulation and Monitoring of Cell Lines - The disclosure relates generally to stem cell biology and more specifically to genetic manipulation of stem cells. Methods and compositions using recombinational cloning techniques are disclosed which allow the construction and insertion of complex genetic constructs into embryonic and adult stem cells and progenitor cells. The methods disclosed will allow the harvesting of adult stem cells pre-engineered with integration sites to facilitate early passage genetic modification. | 09-04-2008 |
20110263001 | Compositions and Methods for Engineering Cells - The disclosure relates generally to genetic manipulation of stem and primary cells and to reprogramming of somatic cells, more specifically, human cells. In particular, compositions and methods are disclosed for the generation and maintenance of such engineered cells. | 10-27-2011 |
20130004946 | Compositions and Methods for Genetic Manipulation and Monitoring of Cell Lines - The disclosure relates generally to stem cell biology and more specifically to genetic manipulation of stem cells. Methods and compositions using recombinational cloning techniques are disclosed which allow the construction and insertion of complex genetic constructs into embryonic and adult stem cells and progenitor cells. The methods disclosed will allow the harvesting of adult stem cells pre-engineered with integration sites to facilitate early passage genetic modification. | 01-03-2013 |
20130040304 | Compositions and Methods for Engineering Cells - The disclosure relates generally to genetic manipulation of stem and primary cells and to reprogramming of somatic cells, more specifically, human cells. In particular, compositions and methods are disclosed for the generation and maintenance of such engineered cells. | 02-14-2013 |
20140335615 | METHODS OF USING MECHANICAL FORCE WITH SOMATIC AND PLURIPOTENT CELLS - Provided are methods useful in increasing efficiency of biotransport, reprogramming or altering a cell's state of differentiation, and maintenance of cells in an undifferentiated state. | 11-13-2014 |
Peter Lieu, Irvine, CA US
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20120068336 | Method for Fabricating a Neo-Layer Using Stud Bumped Bare Die - A method for fabricating a stackable integrated circuit layer and a device made from the method are disclosed. A stud bump is defined on the contact pad of an integrated circuit die and the stud-bumped die encapsulated in a potting material to define a potted assembly. A predetermined portion of the potting material is removed whereby a portion of the stud bump is exposed. One or more electrically conductive traces are defined on the layer surface and in electrical connection with the stud bump to reroute the integrated circuit contacts to predetermined locations on the layer to provide a stackable neolayer. | 03-22-2012 |
20120068341 | Method for Depackaging Prepackaged Integrated Circuit Die and a Product from the Method - A method for providing a known good integrated circuit die having enhanced planarity from a prepackaged integrated circuit die having a surface warpage such as in a ball grid array (BGA) package is provided. A partially-depackaged integrated circuit package is affixed to a substrate with a spacer element there between such that the active surface of the die within the partially depackaged integrated circuit die is “bowed” slightly upwardly to define a convex surface. The exposed encapsulant on the now-convex surface of the mounted, partially-depackaged integrated circuit package is then lapped or ground away to a predetermined depth so that an integrated circuit die is provided having an enhanced planarity and surface uniformity. | 03-22-2012 |
20120211886 | Method for Fabricating a Small Footprint Chip-Scale Package and a Device Made from the Method - A method for fabricating an integrated circuit chip-scale package and a device made from the method. One or more IC chips are mounted on a carrier and a stud bump defined on an IC pad. The stud-bumped IC is encapsulated to define a potted assembly layer which is thinned to expose the stud bump. Conductive first traces are defined and coupled to the stud bump to reroute the IC pads. A dielectric layer is provided and vias defined there through to expose the first traces. Electrically conductive second traces are disposed on the dielectric layer surface that are coupled to the first traces to reroute the IC pads to define a chip scale package. | 08-23-2012 |
Phong Lieu, San Diego, CA US
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20120078071 | ADVANCED CONTINUOUS ANALYTE MONITORING SYSTEM - Systems and methods for processing, transmitting, and displaying data received from a continuous analyte (e.g., glucose) sensor are provided. A sensor system can comprise a sensor electronics module that includes power saving features, e.g., a low power measurement circuit that can be switched between a measurement mode and a low power mode, wherein charging circuitry continues to apply power to electrodes of a sensor during the low power mode. The sensor electronics module can be switched between a low power storage mode and a higher power operational mode via a switch, e.g., a reed switch or optical switch. A validation routine can be implemented to ensure an interrupt signal sent from the switch is valid. The sensor can be physically connected to the sensor electronics module in direct wireless communication with a plurality of different display devices. | 03-29-2012 |
20130267811 | TRANSCUTANEOUS ANALYTE SENSORS, APPLICATORS THEREFOR, AND ASSOCIATED METHODS - The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with pushbutton activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing, all in one smooth motion. Some embodiments contemplate engagement of the transmitter with the housing after release of the applicator. | 10-10-2013 |
20130267812 | TRANSCUTANEOUS ANALYTE SENSORS, APPLICATORS THEREFOR, AND ASSOCIATED METHODS - The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with pushbutton activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing, all in one smooth motion. Some embodiments contemplate engagement of the transmitter with the housing after release of the applicator. | 10-10-2013 |
20130267813 | TRANSCUTANEOUS ANALYTE SENSORS, APPLICATORS THEREFOR, AND ASSOCIATED METHODS - The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with pushbutton activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing, all in one smooth motion. Some embodiments contemplate engagement of the transmitter with the housing after release of the applicator. | 10-10-2013 |
20140266776 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device. | 09-18-2014 |
20140266785 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device. | 09-18-2014 |
20140273821 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device. | 09-18-2014 |
20160058380 | SYSTEMS AND METHODS FOR SECURING A CONTINUOUS ANALYTE SENSOR TO A HOST - Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable. | 03-03-2016 |
20160081551 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device. | 03-24-2016 |
20160081586 | SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device. | 03-24-2016 |
Ricky Lieu, San Diego, CA US
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20080199909 | Methods for Expression and Purification of Recombinant Human Growth Hormone - The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules. | 08-21-2008 |
Tim Lieu, San Leandro, CA US
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20150079924 | Emergency Communications Management - Emergency communications systems and methods are provided herein. According to some embodiments, methods for mediating transmission of an emergency communication may include establishing a communications path between an emergency response entity and a communications device of a reporting party in response to an emergency event, and delivering to the emergency response entity an alert communication from the communications device, the alert communication comprising at least a location of the communications device and visual content captured by the communications device. | 03-19-2015 |
Tim V. Lieu, San Leandro, CA US
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20130315383 | Emergency Communications Management - Emergency communications systems and methods are provided herein. According to some embodiments, methods for mediating transmission of an emergency communication may include establishing a communications path between an emergency response entity and a communications device of a reporting party in response to an emergency event, and delivering to the emergency response entity an alert communication from the communications device, the alert communication comprising at least a location of the communications device and visual content captured by the communications device. | 11-28-2013 |