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Liao, CA

Anna Liao, Montrose, CA US

Patent application numberDescriptionPublished
20090187072ENDOSCOPE AND SYSTEM AND METHOD OF OPERATION THEREOF - An endoscope including a rigid section having opposed first and second ends and an opening situated between the first and second ends, the rigid section defining a longitudinal axis; a handle portion coupled to a first end of the rigid section and having first and second scissor-type handles suitable for grasping by a user; and a base part situated at the second end of the rigid section and coupled to the first handle of the scissor-type handles such that displacement of the first handle causes a rotation of the base part.07-23-2009
20130096381ENDOSCOPE AND SYSTEM AND METHOD OF OPERATION THEREOF - An endoscope including a rigid section having opposed first and second ends and an opening situated between the first and second ends, the rigid section defining a longitudinal axis; a handle portion coupled to a first end of the rigid section and having first and second scissor-type handles suitable for grasping by a user; and a base part situated at the second end of the rigid section and coupled to the first handle of the scissor-type handles such that displacement of the first handle causes a rotation of the base part.04-18-2013

Arthur W. Liao, Cupertino, CA US

Patent application numberDescriptionPublished
20110307895Managing Requests Based on Request Groups - A request management component receives requests to perform an operation. Each of the requests is assigned, based on one or more criteria, to one of multiple different request groups. Based at least in part on execution policies associated with the request groups, determinations are made as to when to submit the requests to one or more recipient. Each of the multiple requests is submitted to one of the recipients when it is determined that the request is to be submitted.12-15-2011

Bryan Liao, Santa Clara, CA US

Patent application numberDescriptionPublished
20090212010PLASMA ETCHING CARBONACEOUS LAYERS WITH SULFUR-BASED ETCHANTS - Etching of carbonaceous layers with an etchant gas mixture including molecular oxygen (O08-27-2009

Bryan Liao, Saratoga, CA US

Patent application numberDescriptionPublished
20110031216SYNCHRONIZED RADIO FREQUENCY PULSING FOR PLASMA ETCHING - Methods for processing a substrate are provided herein. In some embodiments, a method of etching a dielectric layer includes generating a plasma by pulsing a first RF source signal having a first duty cycle; applying a second RF bias signal having a second duty cycle to the plasma; applying a third RF bias signal having a third duty cycle to the plasma, wherein the first, second, and third signals are synchronized; adjusting a phase variance between the first RF source signal and at least one of the second or third RF bias signals to control at least one of plasma ion density non-uniformity in the plasma or charge build-up on the dielectric layer; and etching the dielectric layer with the plasma.02-10-2011
20110162798METHODS AND APPARATUS FOR TUNING MATCHING NETWORKS - Methods and apparatus for tuning matching networks are provided herein. A method of tuning a matching network includes providing a matching network coupling an RF source to a load, the matching network having a tunable element disposed at a first set point; increasing a value of the tunable element by a first step above the first set point; sensing a first adjusted value of a reflected RF power; decreasing the value of the tunable element by the first step below the first set point; sensing a second adjusted value of the reflected RF power; comparing the first and the second adjusted values of the reflected RF power; and moving the tunable element to a second set point that corresponds to a position having a lowest adjusted value of the reflected RF power. The method may be repeated until the reflected RF power falls within an acceptable reflected RF power range.07-07-2011
20130213935SYNCHRONIZED RADIO FREQUENCY PULSING FOR PLASMA ETCHING - Methods for processing a substrate are provided herein. In some embodiments, a method of etching a dielectric layer includes generating a plasma by pulsing a first RF source signal having a first duty cycle; applying a second RF bias signal having a second duty cycle to the plasma; applying a third RF bias signal having a third duty cycle to the plasma, wherein the first, second, and third signals are synchronized; adjusting a phase variance between the first RF source signal and at least one of the second or third RF bias signals to control at least one of plasma ion density non-uniformity in the plasma or charge build-up on the dielectric layer; and etching the dielectric layer with the plasma.08-22-2013

Chiawei Liao, San Jose, CA US

Patent application numberDescriptionPublished
20090140666Dimming control circuit and method for generating analog and digital signals according to one analog control signal - The present invention discloses a dimming control circuit and a method for generating analog and digital signals according to an analog control signal. The dimming control circuit according to the present invention comprises an input for receiving an analog control signal; a digital dimming circuit for receiving the analog control signal and generating a digital signal; an analog dimming circuit for receiving the analog control signal and generating an analog signal; and a power circuit enabled by the digital signal for converting a supply voltage to an output voltage according to the analog signal generated by the analog dimming circuit.06-04-2009
20100084991Dimming Control Circuit - The present invention discloses a dimming control circuit, comprising: an input terminal for receiving an input signal; an analog and digital dimming circuit receiving the input signal, wherein the analog and digital dimming circuit provides an analog dimming function when a voltage level of the input signal is between a predetermined lower limit and a predetermined upper limit, and a digital dimming function when the voltage level of the input signal switches above and below the predetermined lower limit, and wherein the analog and digital dimming circuit generates an analog signal when the voltage level of the input signal is above the predetermined lower limit; and a power circuit for supplying an output current in correspondence to the analog signal generated by the analog and digital dimming circuit.04-08-2010
20100301761Tail-less LED Control Circuit - The present invention discloses a tail-less LED control circuit, which includes: a power supply stage having an output terminal which provides electrical power to an LED circuit; an output capacitor coupled to the output terminal; an LED driver circuit coupled to the power supply stage for controlling the power supply stage to provide the electrical power to the LED circuit, the LED driver circuit receiving a PWM dimming signal for adjusting brightness of the LED circuit; and a MOSFET switch coupled to the output capacitor in series, the MOSFET switch switching synchronously with the PWM dimming signal to alleviate LED afterglow, wherein the MOSFET switch includes a body diode having an anode-cathode direction against the discharge direction of the output capacitor.12-02-2010
20110316424BACKLIGHT CONTROL CIRCUIT - The present invention discloses a backlight control circuit, comprising: a voltage supply circuit for receiving an input voltage and generating an output voltage under control by a control signal; at least one voltage comparison path respectively coupled to at least one light emission device path; a voltage operative amplifier circuit for generating the control signal according to a lowest voltage on the at least one voltage comparison path; and at least one under current detection circuit for detecting whether a corresponding one of the at least one light emission device path is in an under current status, whereby when anyone of the under current detection circuits detects the under current status, it sends an exclusion signal excluding a corresponding one of the at least one voltage comparison path from being an effective input of the voltage operative amplifier.12-29-2011
20140009075Backlight Control Circuit with Under Current Detection and Start-up Control - The present invention discloses a backlight control circuit, comprising: a voltage supply circuit for receiving an input voltage and generating an output voltage under control by a control signal; at least one voltage comparison path respectively coupled to at least one light emission device path; a voltage operative amplifier circuit for generating the control signal according to a lowest voltage on the at least one voltage comparison path; and at least one under current detection circuit for detecting whether a corresponding one of the at least one light emission device path is in an under current status, whereby when anyone of the under current detection circuits detects the under current status, it sends an exclusion signal excluding a corresponding one of the at least one voltage comparison path from being an effective input of the voltage operative amplifier.01-09-2014

Patent applications by Chiawei Liao, San Jose, CA US

Chihyuan Liao, San Diego, CA US

Patent application numberDescriptionPublished
20090267838METHOD AND APPARATUS TO AUTOMATICALLY TRIGGER POSITION LOCATION FIXES FOR EXTERNAL DEVICES - A method and apparatus automatically triggers position location fixes for external devices. In one embodiment of the present invention, a mobile station generates position location data for a position location function in an external device in response to determining that the mobile station is electrically coupled to the external device, and in response to determining that the position location function in the external device is active. The mobile station does not generate position location data for the position location function in the external device in response to determining that the mobile station is electrically decoupled from the external device, or in response to determining that the position location function in the external device is not active.10-29-2009

Chunyuan Liao, Mountain View, CA US

Patent application numberDescriptionPublished
20100331041System and method for language-independent manipulations of digital copies of documents through a camera phone - Method, device, system and framework for enabling token and point level operations on language independent paper documents through camera phone interface. Image descriptors from snapshots of document captured by the phone can be extracted by phone itself and transmitted to server. In another implementation, the descriptors are extracted by receiving server. The server is connected to database of high-quality images of the same document and matched high-quality patch is sent back to phone for user's viewing and manipulation. Modifications and annotations of high-quality patch are transmitted to database and stored. Motion detection is combined with image recognition to provide high quality images of regions of document being viewed by sweeping the phone. Capabilities include web-search, e-dictionary, or keyword finding for words in paper documents, copy-paste operations, constructing photo collages from portions of printed photos, and playing dynamic contents of printed presentation slides on display of camera phone.12-30-2010
20110072355AT-A-DISTANCE MAGIC LENSES FOR PRIVACY-SENSITIVE, COLLABORATIVE DOCUMENT VIEWING ACROSS MOBILE DEVICES AND LARGE DISPLAYS - Systems and Methods that allows multiple users to see a privacy-filtered overview of a document on a large display and that allows them to view on their personal mobile device details of the same document that are specific to their credentials.03-24-2011
20110154174EMBEDDED MEDIA MARKERS AND SYSTEMS AND METHODS FOR GENERATING AND USING THEM - Embedded Media Markers (EMM) are optical-filter-like overlaid marks that can be printed on a part of a paper document that signify the existence of media associated with that part of the document. Users take a picture of an EMM-signified document patch using a cell phone camera, and the media associated with the EMM-signified document location is retrieved and displayed on the phone. Unlike bar codes, EMMs are nearly transparent and thus do not interfere with the document contents. Retrieval of media associated with an EMM is based on image local features of the captured EMM-signified document patch. A semi-automatically technique places an EMM at a location in a document, in such a way that the EMM encompasses sufficient identification features with minimal disturbance to the original document.06-23-2011
20120037695EMBEDDED MEDIA BARCODE LINKS AND SYSTEMS AND METHODS FOR GENERATING AND USING THEM - Embedded Media Barcode Links (EMBL), are optimally blended iconic barcode marks printed on paper documents that signify the existence of media associated with that part of the document. EMBLs are used for media retrieval with a camera phone. Users take a picture of an EMBL-signified document patch using a cell phone, and the media associated with the EMBL-signified document location is displayed on the phone. Unlike traditional bar code which requires an exclusive space, EMBLs are optimally blended with contents and thus have less interference with the original document layout and can be moved closer to a media associated location. Unlike Embedded Media Makers (EMM) which requires underlying document features for the marker identification, EMBL has no requirement to underlying features. Moreover, EMBL can take the advantage of users' knowledge to traditional barcode. Retrieval of media associated with an EMBL is based on the barcode identification of the captured EMBL.02-16-2012
20120042288SYSTEMS AND METHODS FOR INTERACTIONS WITH DOCUMENTS ACROSS PAPER AND COMPUTERS - Systems and methods provide for mixed use of physical documents and a computer, and more specifically provide for detailed interactions with fine-grained content of physical documents that are integrated with operations on a computer to provide for improved user interactions between the physical documents and the computer. The system includes a camera which processes the physical documents and detects gestures made by a user with respect to the physical documents, a projector which provides visual feedback on the physical document, and a computer with a display to coordinate the interactions of the user with the computer and the interactions of the user with the physical document. The system, which can be portable, is capable of detecting interactions with fine-grained content of the physical document and translating interactions at the physical document with the computer display, and vice versa.02-16-2012
20120131516METHOD, SYSTEM AND COMPUTER READABLE MEDIUM FOR DOCUMENT VISUALIZATION WITH INTERACTIVE FOLDING GESTURE TECHNIQUE ON A MULTI-TOUCH DISPLAY - A method, system and computer readable medium for folding a document page object are provided. A method for folding a document page object in a graphical user interface using multi-touch gestures includes establishing at least two contact points on a display; moving at least one of the two contact points to create a fold on the document page object; and displaying the folded document page object.05-24-2012
20130033484SYSTEM AND METHOD FOR INTERACTIVE MARKERLESS PAPER DOCUMENTS IN 3D SPACE WITH MOBILE CAMERAS AND PROJECTORS - Systems and methods directed to fine-grained interaction with ordinary markerless paper documents and projectors at flexible poses in 3D space. Systems and methods allow for the projection of images onto non-flat variable surfaces by utilizing depth detection techniques in order to project an image or video properly onto a variable surface.02-07-2013

Patent applications by Chunyuan Liao, Mountain View, CA US

Daniel Liao, Irvine, CA US

Patent application numberDescriptionPublished
20080246653GPS NAVIGATION USING INTERACTING MULTIPLE MODEL (IMM) ESTIMATOR AND PROBABILISTIC DATA ASSOCIATION FILTER (PDAF) - A method for GPS navigation which uses an interacting multiple-model (IMM) estimator with a probabilistic data association filter (PDAF) improves navigation performance. The method includes (a) providing two or more models of GPS navigation, with each model characterized by a model state vector which is updated periodically, (b) providing for each model a corresponding filter for deriving, for each period, a current value for the corresponding model state vector based on current measurements made on parameters affecting the corresponding state vector; and (c) applying an interacting multiple model (IMM) estimator to provide, for each period, a current value for a system state vector using the current values of the model state vectors for that period and their corresponding filters. Each model state vector may include one or more of the following: variables: 3-dimensional position, 3-dimensional velocity, satellite clock bias, satellite clock drifts and one or more other satellite parameters. The current value of the system state vector may be a weighted average of the current values of the model state vectors, where the weights are a set of mode probabilities. In addition, one or more of the filters is a probabilitic data association filter (PDAF).10-09-2008
20090119015Systems and Methods for Processing Navigational Solutions - Systems and methods for processing navigational solutions are provided. In this regard, a representative system includes a navigational computing device comprising a processor and memory that stores a navigational solution manager that is executed by the processor to provide a receiver position. The navigational solution manager is configured to collect navigational data from at least one satellite vehicle, compute initialization navigational measurements based on the collected navigational data, and compute the receiver position using the initialization navigation measurements.05-07-2009
20090128407Systems and Methods for Detecting GPS Measurement Errors - Systems and methods for detecting global positioning system (GPS) measurement errors are provided. In this regard, a representative system, among others, includes a navigation device that is configured to receive GPS signals from signal sources, the navigation device being configured to calculate pseudoranges (PRs) and delta ranges (DRs) based on the received GPS signals, the navigation device including a consistency check algorithm that is configured to: determine mismatches between the respective calculated PRs and DRs, and indicate that an error exists in the respective calculated PRs and DRs based on their mismatch and mismatch accumulations. This algorithm can be independent of navigation state and is capable of detecting slow-changing errors.05-21-2009

Dongxiang Liao, Sunnyvale, CA US

Patent application numberDescriptionPublished
20080308781STRUCTURE AND PROCESS FOR A RESISTIVE MEMORY CELL WITH SEPARATELY PATTERNED ELECTRODES - Methods of making MIM structures and the resultant MIM structures are provided. The method involves forming a top electrode layer over a bottom electrode and an insulator on a substrate and forming a top electrode by removing portions of the top electrode layer. The bottom electrode, insulator, or combination thereof is isolated from the top electrode forming process, thereby mitigating damage to the resultant metal-insulator-metal structure. The resultant MIM structure can be a portion of a resistive memory cell.12-18-2008
20090067213Method of forming controllably conductive oxide - In fabricating a memory device, a first electrode is provided. An alloy is formed thereon, and the alloy is oxidized to provide an oxide layer. A second electrode is provided on the oxide layer. In a further method of fabricating a memory device, a first electrode is provided. Oxide is provided on the first electrode, and an implantation step in undertaken to implant material in the oxide to form a layer including oxide and implanted material having an oxygen deficiency and/or defects therein. A second electrode is then formed on the layer.03-12-2009
20090109598Metal-insulator-metal (MIM) device and method of formation thereof - In a method of fabricating a metal-insulator-metal (MIM) device, initially, a first electrode is provided. An oxide layer is provided on the first electrode, and a protective layer is provided on the oxide layer. An opening through the protective layer is provided to expose a portion of the oxide layer, and a portion of the first electrode underlying the exposed portion of the oxide layer is oxidized. A second electrode is provided in contact with the exposed portion of the oxide layer. In alternative embodiments, the initially provided oxide layer may be eliminated, and spacers of insulating material may be provided in the opening.04-30-2009
20090109727Erase, programming and leakage characteristics of a resistive memory device - The present method provides annealing of a resistive memory device so as to provide that the device in its erased state has a greatly increased resistance as compared to a prior art approach. The annealing also provides that the device may be erased by application of any of a plurality of electrical potentials within an increased range of electrical potentials as compared to the prior art.04-30-2009
20100193398REUSABLE SAMPLE HOLDING DEVICE PERMITTING READY LOADING OF VERY SMALL WET SAMPLES - A reusable sample-holding device for readily loading very small wet samples for observation of the samples by microscopic equipment, in particular in a vacuum environment. Embodiments may be used with a scanning electron microscope (SEM), a transmission electron microscope (TEM), an X-ray microscope, optical microscope, and the like. For observation of the sample, embodiments provide a thin-membrane window etched in the center of each of two silicon wafers abutting to contain the sample in a small uniform gap formed between the windows. This gap may be adjusted by employing spacers. Alternatively, the thickness of a film established by the fluid in which the sample is incorporated determines the gap without need of a spacer. To optimize resolution each window may have a thickness on the order of 50 nm and the gap may be on the order of 50 nm.08-05-2010
20120017415METHOD OF USE OF REUSABLE SAMPLE HOLDING DEVICE PERMITTING READY LOADING OF VERY SMALL WET SAMPLES - A method for using a reusable sample-holding device for readily loading very small wet samples for observation of the samples by microscopic equipment, in particular in a vacuum environment. The method may be used with a scanning electron microscope (SEM), a transmission electron microscope (TEM), an X-ray microscope, optical microscope, and the like. For observation of the sample, the method provides a thin-membrane window etched in the center of each of two silicon wafers abutting to contain the sample in a small uniform gap formed between the windows. This gap may be adjusted by employing spacers. Alternatively, the thickness of a film established by the fluid in which the sample is incorporated determines the gap without need of a spacer. To optimize resolution each window may have a thickness on the order of 50 nm and the gap may be on the order of 50 nm.01-26-2012
20130237030METAL-INSULATOR-METAL (MIM) DEVICE AND METHOD OF FORMATION THEREOF - In a method of fabricating a metal-insulator-metal (MIM) device, initially, a first electrode is provided. An oxide layer is provided on the first electrode, and a protective layer is provided on the oxide layer. An opening through the protective layer is provided to expose a portion of the oxide layer, and a portion of the first electrode underlying the exposed portion of the oxide layer is oxidized. A second electrode is provided in contact with the exposed portion of the oxide layer. In alternative embodiments, the initially provided oxide layer may be eliminated, and spacers of insulating material may be provided in the opening.09-12-2013

Patent applications by Dongxiang Liao, Sunnyvale, CA US

Fang-Jun Liao, Santa Clara, CA US

Patent application numberDescriptionPublished
20090280660Electrical connector with dual-function protrusions - An electrical connector (11-12-2009

Francesca-Fang Liao, La Jolla, CA US

Patent application numberDescriptionPublished
20090233993COMPOSITIONS AND METHODS FOR INHIBITING GSK3 ACTIVITY AND USES THEREOF - Disclosed herein are compositions and methods relating to peptides. The peptides can inhibit amyloid beta (Aβ) generation and reduce GSK-3 activities. Further provided are compositions and methods for treating or preventing, for example, Alzheimer's disease, cancer, and diabetes.09-17-2009

Frank Jason Liao, Cupertino, CA US

Patent application numberDescriptionPublished
20090169730METHOD OF FORMING CONDUCTORS AT LOW TEMPERATURES USING METALLIC NANOCRYSTALS AND PRODUCT - Metallic nanoparticles are provided which can be used in forming metallic film conductors at reduced temperatures compatible with plastic carriers for the film conductors. This is realized by using a lower molecular weight organic encapsulant of the nanoparticle and thereby reducing the temperature at which the organic encapsulant evaporates. Further, the sintering or melting temperature of the metallic nanoparticle is reduced by using a lower sized nanoparticle, thereby increasing the particle surface area relative to the particle volume and thus reducing the required heat and melting temperature of the particle.07-02-2009

Fred Liao, San Jose, CA US

Patent application numberDescriptionPublished
20090066714Systems and Methods for Managing Texture Data in a Computer - Provided are methods for managing texture data in Graphics Processing Units (GPUs). The methods include receiving, into an arbiter, a preload request configured to request processing of texture data in advance of shader processing and receiving, into the arbiter, a dependent read request configured to request processing of texture data after shader processing. The methods also include receiving, into the arbiter, a capacity signal from a texture buffer and determining, utilizing the virtual buffer capacity signal, a selected request corresponding which of the preload request and the dependent read request is granted. The methods further include processing, in a texture processor, texture data corresponding to the selected request.03-12-2009
20090128575Systems and Methods for Managing Texture Descriptors in a Shared Texture Engine - Provided are methods for managing texture data. The methods include preloading a first plurality of texture descriptor values from a memory location in a first buffer located in a first logic block, wherein the first buffer is further configured to receive data corresponding to non-texture functions performed in the first logic block and preloading the first plurality of texture descriptor values from a memory location into a second buffer in a second logic block if the first buffer is full. The methods further include utilizing the first plurality of texture descriptor values, within the second logic block, to perform a shader calculation, and loading, dynamically, a second plurality of texture descriptor values from memory into the first buffer, wherein the first logic block requires additional data. Additionally, the methods can include writing, if the first buffer is full, the second plurality of texture descriptor values over a portion of the first plurality of texture descriptor values.05-21-2009

Patent applications by Fred Liao, San Jose, CA US

Grace Liao, Irvine, CA US

Patent application numberDescriptionPublished
20100160851Gilled phacoemulsification irrigation sleeve - A phacoemulsification irrigation sleeve includes an elongated, resilient, tubular body section configured to surround a portion of a shaft of a phacoemulsification needle, the tubular body section having a distal end and a proximal end, and an inner surface and an outer surface. An enlarged section formed on the proximal end of the tubular body portion surrounds a hub of the phacoemulsification needle and connects the irrigation sleeve to a phacoemulsification handpiece. The irrigation sleeve further comprises at least one slitted irrigation port formed adjacent to the distal end of the body section and configured to splay in response to a drop in pressure between the inner surface and the outer surface.06-24-2010
20120116290GILLED PHACOEMULSIFICATION IRRIGATION SLEEVE - A phacoemulsification irrigation sleeve includes an elongated, resilient, tubular body section configured to surround a portion of a shaft of a phacoemulsification needle, the tubular body section having a distal end and a proximal end, and an inner surface and an outer surface. An enlarged section formed on the proximal end of the tubular body portion surrounds a hub of the phacoemulsification needle and connects the irrigation sleeve to a phacoemulsification handpiece. The irrigation sleeve further comprises at least one slitted irrigation port formed adjacent to the distal end of the body section and configured to splay in response to a drop in pressure between the inner surface and the outer surface.05-10-2012

Grace Chuang Liao, Irvine, CA US

Patent application numberDescriptionPublished
20100056991MULTI-COMPLIANT TUBING - In various embodiments, aspiration tubing connecting a handpiece to a surgical console may include a high compliant section, a transition section, and a low compliant section. In some embodiments, the high compliant section may have a lower durometer and/or different geometry than the low compliant section. The transition section may take a number of forms, including a connector or a continuous section of tubing that gradually increases in durometer and/or changes geometry through the length of the tubing. In the various embodiments, the high compliant section may provide flexibility near the handpiece to make the handpiece easier to hold and maneuver while the low compliant section may reduce the effects of occlusion break surge. In some embodiments, the high compliant section may include, for example, ribs, stiffening rings, a stiffening sleeve, or a stiffening sock to increase the stiffness of the high compliant section.03-04-2010
20120157934Infusion Sleeve with Multiple Material Layers - A phacoemulsification system is disclosed. The system includes a phacoemulsification handpiece and selectively detachable infusion sleeve. The infusion sleeve may include a single body portion defined by a first open end and a second open end and having a hollow interior portion therein. The body portion may include multiple layers with at least one inner layer and at least one outer layer, such that the layers are constructed of separate and distinct materials.06-21-2012

Guochun Liao, Belmont, CA US

Patent application numberDescriptionPublished
20080317307Systems and methods for alignment of objects in images - Systems and methods for aligning objects in object sets are provided. An object set has objects that are in a corresponding image in a plurality of images. For each respective object in a first object set, a corresponding object group is constructed that contains the respective object, thereby constructing a plurality of object groups. Similarity metrics are computed between object groups and objects in objects sets in order to assign the objects to object groups. The object groups are then refined in order to align objects in the object sets.12-25-2008
20120083417NATIVE-EXTENSION PARALLEL SEQUENCING - The present invention provides methods for native extension parallel sequencing of polynucleotide.04-05-2012
20120172324COMPOSITIONS AND METHODS FOR REDUCING THE RISK OF AGENT-INDUCED LIVER TOXICITY - The present disclosure relates generally to a co-formulation or co-administration of acetaminophen with one or more chemicals that are metabolites or their derivatives in the methionine and glutathione biosynthesis pathways, for protection against acetaminophen-induced liver toxicity. The formulation may comprise acetaminophen and diet supplements such as S-methylmethionine (SMM). The present disclosure also encompasses methods of providing pain or fever relief with protection against acetaminophen-induced liver injury with the formulations described herein. Embodiments of the present disclosure also include co-formulation or co-administration of an agent and one or more other chemicals for reducing agent-induced liver toxicity via depletion of glutathione.07-05-2012
20120252682METHODS AND SYSTEMS FOR SEQUENCING NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments.10-04-2012
20140065604METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments.03-06-2014
20140315724METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments. In one aspect of the invention, methods, systems and reagent kits are provided for sequencing nucleic acid target sequences. Some embodiments of the methods, systems and reagent kits are particularly suitable for sequencing a large number of fragments, particularly long fragments.10-23-2014

Patent applications by Guochun Liao, Belmont, CA US

Heather H. Liao, Los Altos, CA US

Patent application numberDescriptionPublished
20080261898COMPOSITION AND METHOD FOR CANCER TREATMENT AND PREVENTION - Compounds, compositions, methods and kits are provided for treating, reducing the risk of, or preventing diseases and/or conditions, such as diseases associated with angiogenesis and/or abnormal cell proliferation, such as cancer. Compounds of the present invention have antiangiogenic and anti-cancer activity with minimum toxic effects on normal cells. Methods for preparing and manufacturing the compounds and pharmaceutical compositions are also provided.10-23-2008

Henry H. Liao, Los Alamitos, CA US

Patent application numberDescriptionPublished
20090322603Method and system for locating a geographical position using broadcast frequency modulation signals - A method and system for locating and positioning using broadcast frequency modulation (FM) signals, is provided. One implementation involves receiving FM stereo signals from three FM stations at one or more receivers, each stereo signal including a modulated 19 KHz FM pilot tone; and determining a geographical position at each receiver based on the phase difference of the demodulated pilot tones in the received FM signals.12-31-2009
20110041834Two-Axes Solar Tracker System and Apparatus for Solar Panel and Likes - The present invention relates to a simplified and lower cost two-axes tracker for solar PV (photovoltaic) or CPV (concentrated photovoltaic) solar panel, as well as heliostat solar reflectors and solar Stirling engine. In particular, the disclosure addresses a simplified and gravity centered tracker structure with low cost single or dual linear actuators mounted on the side of ground post which is easier for replacement and maintenance at lower cost.02-24-2011
20110041894Method and Apparatus to Lower Cost Per Watt with Concentrated Linear Solar Panel - The present invention proposes a hybrid methodology and apparatus between photovoltaic (PV) and concentrated photovoltaic (CPV) solar panels to lower the photovoltaic solar energy production cost. In particular, the disclosed methodology addresses a simple quasi-parabolic trough PV (QPTPV) low concentration system with greater tolerance to tracker pointing errors. The quasi-parabolic trough (QPT) reflector is defocused to cover the width of a linear solar cells array, which is reduced from a large rectangular solar cells panel. In summary, the QPTPV system consists of low cost quasi-parabolic reflectors, a compact linear PV cells array and a lower cost relaxed pointing 2-axes tracker. The combination of these low cost technologies disclosed can achieve the lowest cost per kilowatt hour of photovoltaic energy production.02-24-2011
20110186040One-Axis Solar Tracker System and Apparatus with Wind Lock Devices - The present invention proposes a one-axis solar tracker system and apparatus which is simple to install, lower cost and with the provision of an electric-magnetic locking device to resist from medium to strongest wind condition like hurricane or typhoon. Solar farms is more and more popular to use one-axis tracker due to lower cost, higher wind resistance and easier for large scale solar farm installation, especially at lower latitude tropic zones. This disclosure proposes a one-axis tracker with multiple posts support using a single or dual linear actuators driving mechanism for rotation. It is also equipped with a wind lock device to lock the solar tracker in horizontal neutral position during strong wind condition such as hurricane or typhoon. The stepwise wind lock device can further be applied to locking the solar tracker following each step of linear actuator activation enabling the disclosed solar tracker to operate in windy conditions.08-04-2011

Hongmei Liao, San Diego, CA US

Patent application numberDescriptionPublished
20100179679Generating Cutting Forms Along Current Flow Direction In A Circuit Layout - Metal is deleted from portions of metal wires in an integrated circuit layout, based upon a width of the metal wires. Preliminary cutting forms having a length and a width are inserted with a first orientation in the portions of metal wire. It is determined if the width of each of the preliminary cutting forms is parallel to a width of the metal wire portions where the preliminary cutting forms are inserted. If the preliminary cutting forms have width parallel to the width of the metal wire portion, the preliminary cutting forms become part of a cutting form final layout. Cutting forms not having widths parallel to the width of the metal wire portions are removed. Cutting forms at different orientations are then inserted where the prior cutting forms were removed from and the process repeats until all portions of the metal wire have cutting forms inserted parallel to the current flow direction.07-15-2010
20110042818Adding Symmetrical Filling Material In An Integrated Circuit Layout - In one embodiment, an integrated circuit has a conductive layer, where the conductive layer has a first set of regions and a second set of fill material regions, and the second set of fill material regions has a line of symmetry. Other embodiments are described and claimed.02-24-2011
20120110531DEFECT AND YIELD PREDICTION FOR SEGMENTS OF AN INTEGRATED CIRCUIT - Defect prediction information is determined for a segment of an integrated circuit layout. Marker information is obtained, for example from user input into a computer design tool, where the marker information defines the segment. A segment can be defined to be any arbitrary portion of the layout and can include portions of multiple blocks. The marker information is used to extract layout information corresponding to the segment. The extracted segment layout information is analyzed to determine the defect prediction information. In one example, the determination involves performing a Critical Area Analysis such that the defect prediction information is a yield prediction value. This process is repeated for multiple segments, and the defect prediction information for the segments is compared to identify the segment most susceptible to defects. The user can modify the design of the segment, and repeat the process to improve yield in the manufacture of the integrated circuit.05-03-2012
20130033277THERMAL AND STRESS GRADIENT BASED RC EXTRACTION, TIMING AND POWER ANALYSIS - Timing, power and SPICE analysis are performed on a circuit layout, based on temperature and stress variations or gradient across the circuit layout. Specifically, the temperature and stress values of individual window locations across the layout are used to obtain temperature and stress variation aware resistance/capacitance (RC), timing, leakage and power values. In addition, in 3D integrated circuits (IC), the stress and thermal variations or gradients of one die may be imported to another die located on a different tier.02-07-2013
20140223389SYSTEM AND METHOD TO DESIGN AND TEST A YIELD SENSITIVE CIRCUIT - A method includes identifying at least a portion of a design of a semiconductor device to be fabricated as a yield sensitive circuit. The method also includes, in response to identifying the yield sensitive circuit, forming a scan chain. Forming the scan chain includes inserting the yield sensitive circuit between a pair of flip flops and connecting the yield sensitive circuit to the pair of flip flops.08-07-2014

Patent applications by Hongmei Liao, San Diego, CA US

Hongyu Liao, Thousand Oaks, CA US

Patent application numberDescriptionPublished
20090163489Inhibitors of PI3 kinase - The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof, that inhibit phosphoinositide 3-kinase;06-25-2009
20100273764INHIBITORS OF PI3 KINASE AND/OR MTOR - The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof;10-28-2010
20120190666Heteroaryl Compounds as PIKK Inhibitors - The present invention provides compounds that are PIKK inhibitors, more specifically, mTOR and/or PI3Kα kinase inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PI3 kinases, more specifically, mTOR and/or PI3Kα, such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.07-26-2012
20130079303Inhibitors of PI3 Kinase and/or mTOR - The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof;03-28-2013

Patent applications by Hongyu Liao, Thousand Oaks, CA US

Hsin-Hsing Liao, San Diego, CA US

Patent application numberDescriptionPublished
20080299921ON-CHIP DIRECTIONAL COUPLER FOR RF TRANSMITTER OUTPUT POWER MEASUREMENT - An integrated circuit radio transceiver and method therefor include circuitry for generating and power amplifying an outgoing RF signal to produce a power amplified outgoing signal, conducting the power amplified outgoing signal down a transmission path that is disposed substantially parallel to a directional coupler formed on a metallization layer of the integrated circuit, producing a sensed signal level sensed in the directional coupler to a power detector and determining the forward output power based upon the sensed signal level.12-04-2008

James C. Liao, Los Angeles, CA US

Patent application numberDescriptionPublished
20090081746BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS - Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.03-26-2009
20090111154BUTANOL PRODUCTION BY RECOMBINANT MICROORGANISMS - Provided are microorganisms that catalyze the synthesis of biofuels from a suitable substrate such as glucose. Also provided are methods of generating such organisms and methods of synthesizing biofuels using such organisms. Provided are microorganisms comprising non-naturally occurring metabolic pathway for the production of higher alcohols.04-30-2009
20100105103ALCOHOL TOLERANT ESCHERICHIA COLI AND METHODS OF PREPARATION THEREOF - The present invention relates to 04-29-2010
20100209986BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS - Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.08-19-2010
20100221800MICROORGANISM ENGINEERED TO PRODUCE ISOPROPANOL - Provided herein are metabolically-modified microorganisms useful for producing biofuels.09-02-2010
20100285546Genetically Modified Microorganisms for Producing Itaconic Acid with High Yields - Genetically modified microorganisms that produce itaconic acid at high yields and uses thereof.11-11-2010
20110201083PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS - Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing higher alcohols including C5-C8 alcohol from a suitable substrate.08-18-2011
20110250660METHOD FOR PRODUCING ALDEHYDE FROM CO2 - The invention provides recombinant microorganisms capable of producing isobutyraldehyde using CO10-13-2011
20110262982ACETOLACTATE SYNTHASE HAVING 2-KETOISOVALERATE DECARBOXYLASE ACTIVITY AND USES THEREOF - Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol, and 2-phenylethanol from a suitable substrate and a recombinant acetolactate synthase having both synthase and decarboxylase activity.10-27-2011
20130029386COMPOSITIONS AND METHODS FOR THE PRODUCTION OF L-HOMOALANINE - Healthcare costs are a significant worldwide, with many patients being denied medications because of their high prices. One approach to addressing this problem involves the biosynthesis of chiral drug intermediates, an environmentally friendly solution that can be used to generate pharmaceuticals at much lower costs than conventional techniques. In this context, embodiments of the invention comprise methods and materials designed to allow microorganisms to biosynthesize the nonnatural amino acid L-homoalanine. As is known in the art, L-homoalanine is a chiral precursor of a variety of pharmaceutically valuable compounds including the anticonvulsant medications levetiracetam (sold under the trade name Keppra®) and brivaracetam, as well as ethambutol, a bacteriostatic antimycobacterial drug used to treat tuberculosis. Consequently, embodiments of the invention can be used in low cost, environmentally friendly processes to generate these and other valuable compounds.01-31-2013
20130130341ELECTRO-AUTOTROPHIC SYNTHESIS OF HIGHER ALCOHOLS - The disclosure provides a process that converts CO05-23-2013
20130203141PRODUCTION OF 1,4-BUTANEDIOL BY RECOMBINANT MICROORGANISMS - Provided herein are metabolically-modified microorganisms useful for producing 1,4-butanediol.08-08-2013
20130288325BIOFUEL AND CHEMICAL PRODUCTION BY RECOMBINANT MICROORGANISMS VIA FERMENTATION OF PROTEINACEOUS BIOMASS - Provided herein are metabolically modified microorganisms characterized by having an increased keto-acid flux when compared with the wild-type organism and comprising at least one polynucleotide encoding an enzyme that when expressed results in the production of a greater quantity of a chemical product when compared with the wild-type organism. The recombinant microorganisms are useful for producing a large number of chemical compositions from various nitrogen containing biomass compositions and other carbon sources. More specifically, provided herein are methods of producing alcohols, acetaldehyde, acetate, isobutyraldehyde, isobutyric acid, n-butyraldehyde, n-butyric acid, 2-methyl-1-butyraldehyde, 2-methyl-1-butyric acid, 3-methyl-1-butyraldehyde, 3-methyl-1-butyric acid, ammonia, ammonium, amino acids, 2,3-butanediol, 1,4-butanediol, 2-methyl-1,4-butanediol, 2-methyl-1,4-butanediamine, isobutene, itaconate, acetoin, acetone, isobutene, 1,5-diaminopentane, L-lactic acid, D-lactic acid, shikimic acid, mevalonate, polyhydroxybutyrate (PHB), isoprenoids, fatty acids, homoalanine, 4-aminobutyric acid (GABA), succinic acid, malic acid, citric acid, adipic acid, p-hydroxy-cinnamic acid, tetrahydrofuran, 3-methyl-tetrahydrofuran, gamma-butyrolactone, pyrrolidinone, n-methylpyrrolidone, aspartic acid, lysine, cadeverine, 2-ketoadipic acid, and/or S-adenosyl-methionine (SAM) from a suitable nitrogen rich biomass.10-31-2013
20140273164NON-CO2 EVOLVING METABOLIC PATHWAY FOR CHEMICAL PRODUCTION - Provided are microorganisms that catalyze the synthesis of chemicals and biochemicals from a suitable carbon source. Also provided are methods of generating such organisms and methods of synthesizing chemicals and biochemicals using such organisms.09-18-2014
20140273165RECOMBINANT MICROORGANISMS HAVING A METHANOL ELONGATION CYCLE (MEC) - Provided are microorganisms that catalyze the synthesis of chemicals and biochemicals from a methanol, methane and/or formaldehyde. Also provided are methods of generating such organisms and methods of synthesizing chemicals and biochemicals using such organisms.09-18-2014
20140377857INTEGRATED ELECTRO-BIOREACTOR - The disclosure provides a process and bioreactor that converts CO12-25-2014

Patent applications by James C. Liao, Los Angeles, CA US

Jessica Huien Liao, San Diego, CA US

Patent application numberDescriptionPublished
20100215874OPTICAL RECORDING MEDIUM WITH INK RECEPTIVE COATING - The instant disclosure relates to an ink jet printable optical recording medium including a substrate having opposing surfaces, namely a recording surface and a printing surface. The printing surface of the substrate is coated with an adhesion promotion layer which includes polyurethane, a high surface area inorganic pigment having a surface area of at least 100 m08-26-2010

Jian Liao, Union City, CA US

Patent application numberDescriptionPublished
20080220442Difference detection methods using isoelectric focusing chips - The present invention provides an isoelectric focusing difference detection method, as well as an isoelectric focusing chip and device. The method entails labeling proteins in the first sample with a first label, and labeling proteins in the second sample with a second, different label, wherein each label has ionic and pH characteristics whereby, upon isoelectric focusing, relative migration of a protein labeled with the first label is substantially the same as relative migration of the same protein labeled with the second label. The samples are subjected to isoelectric focusing to produce a pattern of separated proteins from both samples, which is then detected to compare the protein composition of the samples. The method can be carried with a novel isoelectric focusing chip including a substrate comprising a channel for carrying out isolectric focusing. The substrate includes a non-fluorescent or low-fluorescence material in a detection region of the channel, facilitating direct detection of the pattern of separated proteins, which makes the chip particularly useful for clinical applications, including use disease diagnosis and monitoring.09-11-2008

Jiayu Liao, Carlsbad, CA US

Patent application numberDescriptionPublished
20090075927SWEET TASTE RECEPTORS - This invention provides novel genes and polypeptides of the sweet receptor family, methods for production of the polypeptides, methods for screening compounds that specifically bind to and/or modulate the activity of these polypeptides; and antibodies specific for the polypeptides.03-19-2009
20110117556HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS - The disclosure provides method and composition utilizing fluorescent amino acids and endogenous fluorescent proteins comprising a moiety capable of undergoing FRET. The methods and compositions of the disclosure are useful in analyzing protein structure and function, and screening molecular inhibitors.05-19-2011
20120004198PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS - Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of a metabolic disorder.01-05-2012
20130338044BIOCONJUGATION USING BIFUNCTIONAL LINKERS - A bifunctional linker and method of use is provided that has a spacer molecule with a functional group on one end configured to couple to the surface of a substrate and a function group on the other end that is configured couple to a biomolecule and methods of use. The preferred bifunctional linker has a poly(ethylene glycol) spacer ranging from 3 to 20 ethylene glycol units that has a silane functional group to react with a substrate and an azide functional group that can couple to a biomolecule that includes an alkyne group. The preferred linker can produce an azide-derivatized glass surface in one step and the azide functional group of the spacer can in sequence conjugate with a biomolecule using click chemistry, which can be conducted at low temperature and in aqueous solution.12-19-2013

Patent applications by Jiayu Liao, Carlsbad, CA US

Jinfang Liao, Foster City, CA US

Patent application numberDescriptionPublished
20080254498FLUORESCENT ION INDICATORS AND THEIR APPLICATIONS - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.10-16-2008
20100029017Mono-chlorinated hydroxycoumarin conjugates - The present invention provides fluorescent biopolymers that are amino acid polymers conjugated to multiple mono-chlorinated 3-carbonyl-7-hydroxy-coumarin dyes, and methods of their use. The fluorescent biopolymers containing multiple mono-chlorinated 3-carbonyl-7-hydroxy-coumarin dyes generally exhibit superior fluorescence properties compared to biopolymers labeled with multiple non-chlorinated hydroxycoumarin dyes. The fluorescent biopolymers of the invention in which the amino acid polymer is an antigen-specific antibody are particularly useful for analyzing cells by flow cytometers that are equipped with a violet laser as an excitation source due to their strong absorption at 405 nm and high fluorescence quantum yield.02-04-2010
20100255504Reactive Heterocycle-Substituted 7-Hydroxycoumarins and Their Conjugates - Chemically-reactive, water-soluble, heterocycle-substituted 7-hydroxycoumarin dyes, their bioconjugates and uses are described. The conjugates derived from reactive heterocycle-substituted 7-hydroxycoumarin dyes are used for analyzing biological compounds. These heterocycle-substituted 7-hydroxycoumarin dyes are particularly useful as fluorescent labels for biopolymer detection reagents, such as antibodies or nucleic acid probes. The dye-antibody conjugates of the invention are particularly useful for analyzing analytes using a flow cytometer equipped with a violet laser as an excitation source due to their strong absorption at 405 nm and high fluorescence quantum yield.10-07-2010
20110229924Fluorescent ion indicators and their applications - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.09-22-2011
20120183954LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES - Chemically reactive dyes that are intramolecularly crosslinked with a water-soluble bridge, their bioconjugates and their uses are described. Reactive fluorescent dyes that have a water-soluble bridge are superior to those of conjugates of spectrally non-crosslinked dyes or the dyes that are crosslinked with a hydrophobic bridge. The invention includes reactive fluorescent dyes, their biological conjugates and uses.07-19-2012
20120183986Fluorescent lactone ion indicators and their applications - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.07-19-2012
20140080170FLUORESCENT ION INDICATORS AND THEIR APPLICATIONS - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.03-20-2014
20140378344Carbofluorescein Lactone Ion Indicators and Their Applications - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations are provided.12-25-2014

Patent applications by Jinfang Liao, Foster City, CA US

Jingfang Liao, Foster City, CA US

Patent application numberDescriptionPublished
20100311184AZO HETEROCYCLIC DYES AND THEIR BIOLOGICAL CONJUGATES - Azo heterocyclic compounds that are substantially non-fluorescent or only weakly fluorescent useful as energy acceptors. The chemically reactive compounds possess utility for labeling a wide variety of substances, including biomolecules with the resulted conjugates being highly useful for a variety of energy-transfer assays and applications. The biological conjugates of the disclosure exhibit little or no observable fluorescence and their fluorescence is significantly increased upon a biological stimulation.12-09-2010
20110318772REACTIVE COUMARIN DERIVATIVES AND THEIR USE IN CELLULAR ANALYSES - Chemically reactive 7-hydroxycoumarin derivatives and their application for analyzing cell function, for example in combination with additional fluorescent labels. The coumarin derivatives exhibit a strong absorption at 405 nm and high fluorescence quantum yields.12-29-2011

Jing Wu Gene Liao, Santa Fe Springs, CA US

Patent application numberDescriptionPublished
20090019752Decorative night light device - The present invention, decorative night light device, comprises a supporting frame and a light arrangement. The supporting frame comprises a hollow supporting frame body for providing a replaceable decorative member thereon. The hollow supporting frame body has an inner surface and a continuously light channel indented on the inner surface and defines a peripheral inner wall inclinedly extended from the inner surface. The light arrangement comprise a light control circuit provided at the hollow supporting frame body, and a plurality of illuminators which are electrically connected to the light control circuit and spacedly and inclinedly aligned along the inner wall of the hollow supporting frame body. Each of the illuminators forms as a point of light source for mostly emitting light towards to the middle of the hollow supporting frame body so as to illuminating the decorative member.01-22-2009

Joseph C. Liao, Los Altos, CA US

Patent application numberDescriptionPublished
20080199863PROBES AND METHODS FOR DETECTION OF PATHOGENS AND ANTIBIOTIC RESISTANCE - Described are probes and methods for detecting pathogens and antibiotic resistance of a specimen. The method comprises contacting the specimen with a growth medium; and lysing the specimen to release nucleic acid molecules from the specimen. The lysate of the specimen is contacted with a capture probe immobilized on a substrate, wherein the capture probe comprises an oligonucleotide that specifically hybridizes with a first target nucleic acid sequence region of ribosomal RNA. The lysate is in contact with a detector probe that comprises a detectably labeled oligonucleotide that specifically hybridizes with a second target nucleic acid sequence region of ribosomal RNA. The presence or absence of labeled oligonucleotide complexed with the substrate is determined. Detection of labeled oligonucleotide complexed with the substrate is indicative of the presence of pathogen. Performing the method in the presence and absence of an antibiotic permits detection of antibiotic resistance.08-21-2008
20110027782PROBES AND METHODS FOR DETECTION OF PATHOGENS AND ANTIBIOTIC RESISTANCE - Described are probes and methods for detecting pathogens and antibiotic resistance of a specimen. The method comprises contacting the specimen with a growth medium; and lysing the specimen to release nucleic acid molecules from the specimen. The lysate of the specimen is contacted with a capture probe immobilized on a substrate, wherein the capture probe comprises an oligonucleotide that specifically hybridizes with a first target nucleic acid sequence region of ribosomal RNA. The lysate is in contact with a detector probe that comprises a detectably labeled oligonucleotide that specifically hybridizes with a second target nucleic acid sequence region of ribosomal RNA. The presence or absence of labeled oligonucleotide complexed with the substrate is determined. Detection of labeled oligonucleotide complexed with the substrate is indicative of the presence of pathogen. Performing the method in the presence and absence of an antibiotic permits detection of antibiotic resistance.02-03-2011

Ling Liao, Santa Clara, CA US

Patent application numberDescriptionPublished
20080277647Materials and Optical Devices Based on Group IV Quantum Wells Grown on Si-Ge-Sn Buffered Silicon - A semiconductor structure including a single quantum well Ge11-13-2008
20100080504Method and Apparatus for High Speed Silicon Optical Modulation Using PN Diode - A method and apparatus for high speed silicon optical modulation is described using a PN diode. In one example, an optical waveguide has adjoining first and second doped semiconductor regions. The first and second regions have opposite doping types and the first doped region extends in two perpendicular directions through the waveguide.04-01-2010

Patent applications by Ling Liao, Santa Clara, CA US

Maofu Liao, San Francisco, CA US

Patent application numberDescriptionPublished
20090280473Inhibition of membrane fusion proteins - Methods of inhibiting viral infection of a eukaryotic cell by a target virus having a class II virus fusion protein are provided. Also provided are methods of screening a test compound for the ability to inhibit infection by a virus having a class II viral fusion protein. Additionally provided herewith are aqueous-soluble proteins comprising a portion of a class II viral fusion protein comprising a Domain III of the viral fusion protein.11-12-2009

Raymond Liao, Pleasanton, CA US

Patent application numberDescriptionPublished
20080240042High-Density Wireless Local Area Network - A data communication system includes an access point and a plurality of stations each for exchanging wireless data communication messages with the access point. At least some of the messages are in a format that includes at least one message header and a plurality of data units. Each of the data units includes a respective data unit header and a respective data frame. Each data unit header identifies a respective one of the stations as a recipient to receive the respective data frame of the data unit.10-02-2008
20080240063High-Density Wireless Local Area Network - A data communication system includes an access point and a plurality of stations each for exchanging wireless data communication messages with the access point. At least some of the messages are in a format that includes at least one message header and a plurality of data units. Each of the data units includes a respective data unit header and a respective data frame. Each data unit header identifies a respective one of the stations as a recipient to receive the respective data frame of the data unit.10-02-2008
20080240069High-Density Wireless Local Area Network - A data communication system includes an access point and a plurality of stations each for exchanging wireless data communication messages with the access point. At least some of the messages are in a format that includes at least one message header and a plurality of data units. Each of the data units includes a respective data unit header and a respective data frame. Each data unit header identifies a respective one of the stations as a recipient to receive the respective data frame of the data unit.10-02-2008
20080240071High-Density Wireless Local Area Network - A data communication system includes an access point and a plurality of stations each for exchanging wireless data communication messages with the access point. At least some of the messages are in a format that includes at least one message header and a plurality of data units. Each of the data units includes a respective data unit header and a respective data frame. Each data unit header identifies a respective one of the stations as a recipient to receive the respective data frame of the data unit.10-02-2008
20080274741High-Density Wireless Local Area Network - A data communication system includes an access point and a plurality of stations each for exchanging wireless data communication messages with the access point. At least some of the messages are in a format that includes at least one message header and a plurality of data units. Each of the data units includes a respective data unit header and a respective data frame. Each data unit header identifies a respective one of the stations as a recipient to receive the respective data frame of the data unit.11-06-2008

Raymond Rui-Feng Liao, Pleasanton, CA US

Patent application numberDescriptionPublished
20100046583Reliable Wireless Communication System Using Adaptive Frequency Hopping - A method and system, the method including determining a frequency quality measurement value for each of a plurality of frequencies a network coordinator can use in a frequency hopping sequence for communicating with a client, classifying each of the plurality of communication frequencies into one of a plurality of different categories based on a relative ranking of the determined frequency quality measurement value of each of the plurality of frequencies, generating, by the network coordinator, a frequency hopping sequence to be used for communication between the network coordinator and the client, the generated hopping sequence including only select frequencies from the plurality of frequencies in a predetermined number of future time slots that minimize a probability of a predetermined number of consecutive frequency hop failures in the predetermined number of future time slots, and notifying the client of the generated frequency hopping sequence to be used for communication.02-25-2010
20100046585Frequency Hopping Network with a Guaranteed Handoff Delay - A system and method for operating a communications system network, the method including operating an access point (AP) acting as a network controller in a frequency hopping network, the AP communicating with other communication devices of the network over m number of frequencies using a hopping sequence of at least some of the m number of frequencies and a dwell time d for the plurality of frequencies; and operating a communication device seeking to establish synchronized communication with other communication devices of the frequency hopping network without any cross-AP coordination, the communication device scanning all of the m number of frequencies using a scanning time s for each of the m number of frequencies; and, wherein the scanning time s is no greater than 1/m of the AP dwell time d.02-25-2010
20100245357Signal Source Data Input for Radio Frequency Planning - A method includes displaying a reference polar coordinate system on a display screen, and displaying a radiation pattern image on the display screen in juxtaposition with the displayed reference polar coordinate system. In another aspect, an angled line is drawn on a display screen to represent the proposed layout of a leaky coaxial cable. A point of interest is selected that is spaced from the proposed cable layout, and one of the segments of the cable is determined as likely to produce a dominant level of irradiation with respect to the point of interest.09-30-2010

Richard Guoyu Liao, Cupertino, CA US

Patent application numberDescriptionPublished
20100161965Secure Credential Store - A credential store provides for secure storage of credentials. A credential stored in the credential store is encrypted with the public key of a user owning the credential. A first user may provide a credential owned by the first user to a second user. The first user may add credentials owned by the first user to the credential store. An administrator may manage users of the credential store without having the ability to provide credentials to those users.06-24-2010
20130311773SECURE CREDENTIAL STORE - A credential store provides for secure storage of credentials. A credential stored in the credential store is encrypted with the public key of a user owning the credential. A first user may provide a credential owned by the first user to a second user. The first user may add credentials owned by the first user to the credential store. An administrator may manage users of the credential store without having the ability to provide credentials to those users.11-21-2013

Shih-Wei Liao, Palo Alto, CA US

Patent application numberDescriptionPublished
20100281471METHODS AND APPARATUSES FOR COMPILER-CREATING HELPER THREADS FOR MULTI-THREADING - Methods and apparatuses for compiler-created helper thread for multi-threading are described herein. In one embodiment, exemplary process includes identifying a region of a main thread that likely has one or more delinquent loads, the one or more delinquent loads representing loads which likely suffer cache misses during an execution of the main thread, analyzing the region for one or more helper threads with respect to the main thread, and generating code for the one or more helper threads, the one or more helper threads being speculatively executed in parallel with the main thread to perform one or more tasks for the region of the main thread. Other methods and apparatuses are also described.11-04-2010

Shih-Wei Liao, San Jose, CA US

Patent application numberDescriptionPublished
20080243943Method and apparatus for efficient execution of interprocedural transactional memory code while maintaining safety - In some embodiments, a method and apparatus for efficient execution of interprocedural transactional memory code while maintaining safety are presented. In this regard, a transaction agent is introduced to start a transactional memory transaction from a first procedure of a program, and to end the transaction from a second procedure of the program. Other embodiments are also disclosed and claimed.10-02-2008

Patent applications by Shih-Wei Liao, San Jose, CA US

Shirong Liao, Mira Loma, CA US

Patent application numberDescriptionPublished
20110068425Optical device having light sensor employing horizontal electrical field - The device includes an optical waveguide on a base. The waveguide is configured to guide a light signal through a light-transmitting medium. A light sensor is also positioned on the base. The light sensor including a ridge extending from slab regions. The slab regions are positioned on opposing sides of the ridge. A light-absorbing medium is positioned to receive at least a portion of the light signal from the light-transmitting medium included in the waveguide. The light-absorbing medium is included in the ridge and also in the slab regions. The light-absorbing medium includes doped regions positioned such that an application of a reverse bias across the doped regions forms an electrical field in the light-absorbing medium included in the ridge.03-24-2011
20110142391Ring resonator with wavelength selectivity - The ring resonator includes waveguides configured to guide light signals. The waveguides include an input waveguide and one or more loop waveguides. One of the loop waveguides is a primary loop waveguide that is optically coupled with the input waveguide at a wavelength of light. A tuner is configured to tune the wavelength at which the light is optically coupled from the input waveguide into the primary loop waveguide. One or more light detectors are each configured to provide an output indicating an intensity of light guided in one of the one or more loop waveguides. Electronics are configured to tune the tuner in response to the output from the light detector.06-16-2011
20110206313Reducing optical loss in an optical modulator using depletion region - An optical device includes a light-transmitting medium positioned on a base. The light-transmitting medium includes a slab region and a ridge extending upward from the slab region. The ridge defines a portion of an optical waveguide on the device. A modulator is also positioned on the base. The modulator includes a first doped region of the light-transmitting medium and a second doped region of the light-transmitting medium. The first doped region and the second doped region are configured such that a depletion region forms in the waveguide when an electrical bias is not applied to the modulator. At least a portion of the first doped region is positioned in the ridge and at least a portion of the second doped region is positioned in the slab region. The light-transmitting medium includes a first electrical pathway extending from a first location to the first doped region. The first location is on top of the light-transmitting medium and is spaced apart from the ridge.08-25-2011
20110310467System having light sensor with enhanced sensitivity - The system includes a light-transmitting medium positioned on a base. The light-transmitting medium included a ridge and a slab region. The ridge extends upward from the slab region and defines a portion of a waveguide on the base. The waveguide is configured to guide a light signal through the device. The device also includes an avalanche effect light sensor positioned on the base and configured to detect the presence of the light signal. The light sensor includes a light-absorbing medium positioned on the ridge of the light-transmitting medium such that the light signal is coupled from the light-transmitting medium into the light-absorbing medium. The light-transmitting includes a charge layer located at an interface of the light-transmitting medium and the light-absorbing medium. A multiplication region is formed in the slab regions of the light-transmitting medium such that the multiplication region receives charge carriers from the charge layer during the operation of the light sensor.12-22-2011
20130195397Optical component having reduced dependency on etch depth - An optical device includes an active component on a base. The active component is a light sensor and/or a light modulator. The active component is configured to guide a light signal through a ridge of an active medium extending upwards from slab regions of the active medium. The slab regions are on opposing sides of the ridge. The active medium includes a doped region that extends into a lateral side of the ridge and also into one of the slab regions. The depth that the doped region extends into the slab region is further than the depth that the doped region extends into the ridge.08-01-2013
20130195398Optical component having reduced dependency on etch depth - An optical device includes an active component on a base. The active component is a light sensor and/or a light modulator. The active component is configured to guide a light signal through a ridge of an active medium extending upwards from slab regions of the active medium. The slab regions are on opposing sides of the ridge. The active medium includes a doped region that extends into a lateral side of the ridge and also into one of the slab regions. The depth that the doped region extends into the slab region is further than the depth that the doped region extends into the ridge.08-01-2013
20140050492REVERSE CONDUCTIVE NANO ARRAY AND MANUFACTURING METHOD OF THE SAME - A high-speed photodiode may include a photodiode structure having a substrate, a light-absorbing layer and a light-directing layer that is deposited on a top surface of the photodiode structure and patterned to form a textured surface used to change the angle of incident light to increase a light path of the incident light when entering the photodiode structure. In one embodiment, the light-directing layer may include a plurality of polygon such as triangular projections to refract the incident light to increase the light path thereof when entering the photodiode structure. In another embodiment, a plurality of nanoscaled sub-triangular projections can patterned on both sides of each triangular projection to more effectively increase the light paths. In a further embodiment, porous materials can be used to form the light-directing layer.02-20-2014
20140332918ENHANCING THE PERFORMANCE OF LIGHT SENSORS THAT RECEIVE LIGHT SIGNALS FROM AN INTEGRATED WAVEGUIDE - The light sensor and waveguide are positioned on a base such that a light signal guided by the waveguide is received at the light sensor. The waveguide includes a taper configured such that a ratio of a width of the waveguide at a first location in the taper:the width of the waveguide at a second location in the taper is greater than 1.2:1 where a length of the taper between the first location and the second location is less than 60 μm.11-13-2014

Patent applications by Shirong Liao, Mira Loma, CA US

Sophia Liao, Irvine, CA US

Steve Shih-Wei Liao, Palo Alto, CA US

Patent application numberDescriptionPublished
20100211940Post-pass binary adaptation for software-based speculative precomputation - The latencies associated with cache misses or other long-latency instructions in a main thread are decreased through the use of a simultaneous helper thread. The helper thread is a speculative prefetch thread to perform a memory prefetch for the main thread. The instructions for the helper thread are dynamically incorporated into the main thread binary during post-pass operation of a compiler.08-19-2010
20100332811SPECULATIVE MULTI-THREADING FOR INSTRUCTION PREFETCH AND/OR TRACE PRE-BUILD - The latencies associated with retrieving instruction information for a main thread are decreased through the use of a simultaneous helper thread. The helper thread is a speculative prefetch thread to perform instruction prefetch and/or trace pre-build for the main thread.12-30-2010
20110067011TRANSFORMATION OF SINGLE-THREADED CODE TO SPECULATIVE PRECOMPUTATION ENABLED CODE - In one embodiment a thread management method identifies in a main program a set of instructions that can be dynamically activated as speculative precomputation threads. A wait/sleep operation is performed on the speculative precomputation threads between thread creation and activation, and progress of non-speculative threads is gauged through monitoring a set of global variables, allowing the speculative precomputation threads to determine its relative progress with respect to non-speculative threads.03-17-2011

Steve Shih-Wei Liao, San Jose, CA US

Patent application numberDescriptionPublished
20080215861METHOD AND APPARATUS FOR EFFICIENT RESOURCE UTILIZATION FOR PRESCIENT INSTRUCTION PREFETCH - Embodiments of an apparatus, system and method enhance the efficiency of processor resource utilization during instruction prefetching via one or more speculative threads. Renamer logic and a map table are utilized to perform filtering of instructions in a speculative thread instruction stream. The map table includes a yes-a-thing bit to indicate whether the associated physical register's content reflects the value that would be computed by the main thread. A thread progress beacon table is utilized to track relative progress of a main thread and a speculative helper thread. Based upon information in the thread progress beacon table, the main thread may effect termination of a helper thread that is not likely to provide a performance benefit for the main thread.09-04-2008
20110035555METHOD AND APPARATUS FOR AFFINITY-GUIDED SPECULATIVE HELPER THREADS IN CHIP MULTIPROCESSORS - Apparatus, system and methods are provided for performing speculative data prefetching in a chip multiprocessor (CMP). Data is prefetched by a helper thread that runs on one core of the CMP while a main program runs concurrently on another core of the CMP. Data prefetched by the helper thread is provided to the helper core. For one embodiment, the data prefetched by the helper thread is pushed to the main core. It may or may not be provided to the helper core as well. A push of prefetched data to the main core may occur during a broadcast of the data to all cores of an affinity group. For at least one other embodiment, the data prefetched by a helper thread is provided, upon request from the main core, to the main core from the helper core's local cache.02-10-2011

Patent applications by Steve Shih-Wei Liao, San Jose, CA US

Swanwa Liao, Woodland Hills, CA US

Patent application numberDescriptionPublished
20090079738SYSTEM AND METHOD FOR LOCATING ANATOMIES OF INTEREST IN A 3D VOLUME - A system and method for modifying a curved cut plane of a 3D volume to locate objects or sections of interest within the 3D volume intersected by the cut plane. A cross-section of the 3D volume along an initially estimated curved cut plane is projected onto a flat viewing plane, and a panorama image of the cross-section is displayed to the user. If the initially estimated curved cut plane does not exactly intersect the object or section of interest, the user manipulates a user input device to modify the curve of the plane inward or outward in the 3D volume away from the projected plane. As the user manipulates the user input device, an affected portion of the curve is recalculated and a modified curved cut plane is reconstructed based on the recalculated curve for re-projecting a modified cross-section of the 3D volume in real time with the movement of the user input device. The user is therefore provided with instant visual feedback as the user moves the user input device to browse in and out within the 3D volume from the current projected plane.03-26-2009
20120257841System and Method for Simulated Linearization of Curved Surface - In accordance with embodiments of the present disclosure, a method may include mapping an ellipse with its center at the origin of an xy-coordinate plane to a circle with its center at the origin of the xy-coordinate plane. The method may also include transforming a three-dimensional subject image including a curved profile in the xy-coordinate plane to an intermediate image based at least on the mapping of the ellipse to a base circle. The method may further include transforming the intermediate image to a transformed image having a linear profile by distorting each of one or more points of interest of the intermediate image based at least on a dimension of the circle and a coordinate of such point.10-11-2012
20120259592System and Method for Three-Dimensional Maxillofacial Surgical Simulation and Planning - A method may include displaying one or more interactive 2D images, each 2D image representing at least bony tissue cranio-facial features of a patient and each 2D image having one or more portions each associated with a corresponding portion of the patient's bony. The method may also include displaying a 3D image representing exterior soft-tissue cranio-facial features of the patient. The method may additionally include receiving input from a user regarding movement of a particular portion of the one or more portions of the 2D image. The method may further include redrawing the 3D image based at least on the movement of the particular portion of the 2D image to simulate response of the exterior soft-tissue cranio-facial features of the patient to movement of a portion of the patient's bony tissue corresponding to the particular portion of the 2D image.10-11-2012

Ten-Luen T. Liao, S. Pasadena, CA US

Patent application numberDescriptionPublished
20100264358IN-SITU GROWTH OF MAGNETIC METAL NANOPARTICLES IN A MATRIX - Provided is a method for in-situ coating a substrate or matrix with magnetic metal nanoparticles. A metal salt, which may be organic or inorganic, is introduced into a solution of liquid polyol. In the presence of mechanical stirring and heat, a reduction process occurs wherein the magnetic metal nanoparticles precipitate out of solution and deposit or attach to one or more surfaces of the substrate. The concentration of reaction precursors, combined with the polyol, may be varied to control the size and shape of the magnetic nanoparticles.10-21-2010
20100327855PTFE GRAPHITE COATING COMPOSITION, METHOD AND APPARATUS - A non-stick coating application for high heat welding environments comprised of a fluorinated polymer combined with acidified graphite to which a hardening agent, such as alumina, may be added in some embodiments.12-30-2010
20110215027PTFE Graphite Coating Composition, Method and Apparatus - A non-stick coating application for high heat welding environments comprised of a fluorinated polymer combined with acidified graphite to which a hardening agent, such as alumina, may be added in some embodiments.09-08-2011
20110223324PTFE Graphite Coating Composition, Method and Apparatus - A non-stick coating application for high heat welding environments comprised of a fluorinated polymer combined with acidified graphite to which a hardening agent, such as alumina, may be added in some embodiments.09-15-2011

Tony Ten-Luen Liao, South Pasadena, CA US

Patent application numberDescriptionPublished
20110268974METHOD AND APPARATUS FOR COATING SUBSTRATES - According to various embodiments, a coating mixture is capable of being applied on a substrate. The coating mixture includes acidified graphite particles, a suspension of polytetrafluoroethylene resin in water, and silver ion doped microporous particles. When the coating mixture is applied to a surface of the substrate, the coating resists growth of microorganisms.11-03-2011
20130334130NOVEL FOULING RESISTANT COATING FOR FILTRATION MEMBRANES AND METHODS OF PRODUCING AND USING SAME - A conformal coating that resists fouling by waterborne contamination in aquatic environments, a method for fabricating the coating, and a filter having such a coating are disclosed. The coating comprises a hydrophilic polymer and a surfactant wherein the surfactant undergoes a phase change upon exposure to a saline solution. Also disclosed are in situ methods for regenerating anti-fouling filters having the fouling resistant coating.12-19-2013
20140287221COATED INDUSTRIAL AUTOMATION DEVICE - According to various embodiments, a coating mixture is capable of being applied on a substrate. The coating mixture includes acidified graphite particles, a suspension of polytetrafluoroethylene resin in water, and silver ion doped microporous particles. When the coating mixture is applied to a surface of the substrate, the coating resists growth of microorganisms.09-25-2014

Patent applications by Tony Ten-Luen Liao, South Pasadena, CA US

Uland Liao, Irvine, CA US

Patent application numberDescriptionPublished
20090054255MICROFLUIDIC DEVICES AND METHODS - Contemplated microfluidic devices and methods are drawn to protein arrays in which distinct and detergent-containing antigen preparations are deposited onto an optical contrast layer in a non-specific and non-covalent manner. Detection of binding a is carried out using a dye that precipitates or agglomerates to so form a visually detectable signal at a dynamic range of at least three orders of magnitude.02-26-2009
20120149600MICROFLUIDIC DEVICES AND METHODS - Contemplated microfluidic devices and methods are drawn to protein arrays in which distinct and detergent-containing antigen preparations are deposited onto an optical contrast layer in a non-specific and non-covalent manner. Detection of binding a is carried out using a dye that precipitates or agglomerates to so form a visually detectable signal at a dynamic range of at least three orders of magnitude.06-14-2012

Wei Liao, Santa Monica, CA US

Patent application numberDescriptionPublished
20100330706PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR - The present invention provides methods of making polymer-based biosensors and the biosensors made by said methods, wherein the biosensors comprise conducting polymers and negatively charged nanoparticles comprising a capture moiety. The present invention also provides methods of detecting analytes in a solution by contacting the solution with said polymer-based biosensors.12-30-2010

Wilson Y. Liao, Belmont, CA US

Patent application numberDescriptionPublished
20090089546Multiple multi-threaded processors having an L1 instruction cache and a shared L2 instruction cache - In general, in one aspect, the disclosure describes a processor that includes an instruction store to store instructions of at least a portion of at least one program and multiple engines coupled to the shared instruction store. The engines provide multiple execution threads and include an instruction cache to cache a subset of the at least the portion of the at least one program from the instruction store, with different respective portions of the engine's instruction cache being allocated to different respective ones of the engine threads.04-02-2009

X. Charlene Liao, Palo Alto, CA US

Patent application numberDescriptionPublished
20080260719EDG: Modulators of lymphocyte activation and migration - The present invention relates to regulation of lymphocyte activation and migration. More particularly, the present invention is directed to nucleic acids encoding EDG family GPCR proteins, e.g., EDG-1, 2, 3, 4, 5, 6, 7, or 8, which are involved in modulation of lymphocyte activation and migration. The invention further relates to methods for identifying and using agents, including small organic molecules, antibodies, peptides, cyclic peptides, nucleic acids, antisense nucleic acids, sphingolipid analogs, and ribozymes, that modulate lymphocyte activation or migration via modulation of EDG GPCRs and EDG related signal transduction; as well as to the use of expression profiles and compositions in diagnosis and therapy related to lymphocyte activation and suppression, and lymphocyte migration.10-23-2008
20130243750ANTI-IGE ANTIBODIES AND METHODS USING SAME - This invention provides anti-IgE antibodies that bind to the M1′ segment of a human IgE and their use in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.09-19-2013

Patent applications by X. Charlene Liao, Palo Alto, CA US

Xiangqian Liao, Irvine, CA US

Patent application numberDescriptionPublished
20090195446System and Method for Verifying Consistent Measurements in Performing GPS Positioning - Systems and methods are provided for verifying whether a set of satellite signals may be used to calculate an estimated position. Example systems and methods may include a GPS receiver for receiving the satellite signals and a measurement consistency verifier to analyze a geometric configuration of the satellites from which the satellite signals were acquired. The measurement consistency verifier may determine if the satellites are sufficiently close to one another to provide consistent measurements.08-06-2009

Xiugao Liao, Irvine, CA US

Patent application numberDescriptionPublished
20100211170COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS - Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.08-19-2010
20120245684COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS - Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.09-27-2012
20130245756COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS - Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.09-19-2013

Patent applications by Xiugao Liao, Irvine, CA US

Yen C. Liao, San Mateo, CA US

Patent application numberDescriptionPublished
20100022823METHODS AND DEVICES FOR TISSUE GRASPING AND ASSESSMENT - Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.01-28-2010
20100298929METHODS, SYSTEMS AND DEVICES FOR CARDIAC VALVE REPAIR - Disclosed are methods, systems, and devices for the endovascular repair of cardiac valves, particularly the atrioventricular valves which inhibit back flow of blood from a heart ventricle during contraction. The procedures described herein can be performed with interventional tools, guides and supporting catheters and other equipment introduced to the heart chambers from the patient's arterial or venous vasculature remote from the heart. The interventional tools and other equipment may be introduced percutaneously or may be introduced via a surgical cut down, and then advanced from the remote access site through the vasculature until they reach the heart.11-25-2010
20120010461METHODS AND DEVICES FOR TISSUE GRASPING AND ASSESSMENT - Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.01-12-2012
20140066693METHODS AND DEVICES FOR TISSUE GRASPING AND ASSESSMENT - Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.03-06-2014

Patent applications by Yen C. Liao, San Mateo, CA US

Yen C. Liao, San Mareo, CA US

Patent application numberDescriptionPublished
20090177266METHODS, SYSTEMS AND DEVICES FOR CARDIAC VALVE REPAIR - Disclosed are methods, systems, and devices for the endovascular repair of cardiac valves, particularly the atrioventricular valves which inhibit back flow of blood from a heart ventricle during contraction. The procedures described herein can be performed with interventional tools, guides and supporting catheters and other equipment introduced to the heart chambers from the patient's arterial or venous vasculature remote from the heart. The interventional tools and other equipment may be introduced percutaneously or may be introduced via a surgical cut down, and then advanced from the remote access site through the vasculature until they reach the heart.07-09-2009

Yi Liao, Santa Rosa, CA US

Patent application numberDescriptionPublished
20110305112Seismic sensor array devices and methods of data collection - A sensor vehicle of the present invention has one or more rotatable track means (parallel if two or more) spaced apart by a support frame and adapted to be towed or otherwise moved in a forward direction parallel to a forward axis of said track means. Rotatable track means have two or more supporting wheels aligned on a vertical plane along the forward axis, which axis is generally parallel to a ground surface upon which said sensor vehicle travels. Tracked vehicles are well known in the art of ground and earth moving equipment having flexible, elastomer-based tracks or segmented metal tracks with associated support frames and wheels, most of which may be adapted to achieve the objects of the invention.12-15-2011

Yi-Chun Liao, San Jose, CA US

Patent application numberDescriptionPublished
20100162899PORTABLE BREWING APPARATUS - A brewing device comprising a brewing system; a handle assembly coupled to the brewing system and containing a source of compressed fluid; and a valve system, coupled to the handle, to selectively place the source of compressed fluid in fluid communication with the brewing system.07-01-2010

Yuansong Liao, San Diego, CA US

Patent application numberDescriptionPublished
20100042454SYSTEM AND METHOD OF DETECTING MORTGAGE RELATED FRAUD - Embodiments include systems and methods of detecting fraud. In particular, one embodiment includes a system and method of detecting fraud in mortgage applications. For example, one embodiment includes a computerized method of detecting fraud that includes receiving mortgage data associated with an applicant and at least one entity related to processing of the mortgage data, determining a first score for the mortgage data based at least partly on a first model that is based on data from a plurality of historical mortgage transactions associated with the entity, and generating data indicative of fraud based at least partly on the first score. Other embodiments include systems and method of generating models for use in fraud detection systems.02-18-2010
20100145836SYSTEM AND METHOD OF DETECTING FRAUD - Embodiments include systems and methods of detecting fraud. In particular, one embodiment includes a system and method of detecting fraud in transaction data such as payment card transaction data. For example, one embodiment includes a computerized method of detecting that comprises receiving data associated with a financial transaction and at least one transacting entity, wherein the data associated with the transacting entity comprises at least a portion of each of a plurality of historical transactions of the transacting entity, applying the data to at least one first model, generating a score based on the first model, and generating data indicative of fraud based at least partly on the score. Other embodiments include systems and methods of generating models for use in fraud detection systems.06-10-2010

Yun-Hsin Kevin Liao, Santa-Clara, CA US

Patent application numberDescriptionPublished
20090269498METHOD FOR MAKING THERMAL INTERFACE MATERIAL - A method for making a thermal interface material includes the steps of: (a) providing an array of carbon nanotubes formed on a substrate, the carbon nanotubes having interfaces defined therebetween; (b) providing a transferring device and disposing at least one low melting point metallic material above the array of carbon nanotubes, using the transferring device; and (c) heating the low melting point metallic material and the array of carbon nanotube to a certain temperature to make the at least one low melting point metallic material melt, then flow into the interspaces between the carbon nanotubes, and combine (e.g., mechanically) with the array of carbon nanotubes to acquire a carbon-nanotube-based thermal interface material.10-29-2009
20100065981Method for fabricating carbon nanotube yarn - A method for fabricating a carbon nanotube yarn includes providing a plurality of carbon nanotube arrays; pulling out, by using a tool, a first carbon nanotube structure from one of the carbon nanotube arrays; pulling out a subsequent carbon nanotube structure from another one of the carbon nanotube arrays; joining a leading end of the subsequent carbon nanotube structure to a trailing portion of the carbon nanotube structure already formed by contacting the leading end of the subsequent carbon nanotube structure with the trailing portion of the already-formed carbon nanotube structure, with the contact occurring along a common lengthwise direction of the two carbon nanotube structures, thereby forming a lengthened carbon nanotube structure; repeating the pulling and the joining until the lengthened carbon nanotube structure has a desired length; and treating the lengthened carbon nanotube structure with an organic solvent.03-18-2010

Yu-Song Liao, San Jose, CA US

Patent application numberDescriptionPublished
20100199134DETERMINING SECTOR STATUS IN A MEMORY DEVICE - The present disclosure includes methods, devices, modules, and systems for operating semiconductor memory. A number of method embodiments include reading data from memory cells corresponding to a sector of data, determining a number of the memory cells in a non-erased state, and, if the number of the memory cells in a non-erased state is less than or equal to a number of errors correctable by an ECC engine, determining the sector is erased.08-05-2010
20100262721MEMORY CONTROLLERS, MEMORY SYSTEMS, SOLID STATE DRIVES AND METHODS FOR PROCESSING A NUMBER OF COMMANDS - The present disclosure includes methods and devices for a memory controller. In one or more embodiments, a memory controller includes a plurality of back end channels, and a command queue communicatively coupled to the plurality of back end channels. The command queue is configured to hold host commands received from a host. Circuitry is configured to generate a number of back end commands at least in response to a number of the host commands in the command queue, and distribute the number of back end commands to a number of the plurality of back end channels.10-14-2010
20120011335MEMORY CONTROLLERS, MEMORY SYSTEMS, SOLID STATE DRIVES AND METHODS FOR PROCESSING A NUMBER OF COMMANDS - The present disclosure includes methods and devices for a memory controller. In one or more embodiments, a memory controller includes a plurality of back end channels, and a command queue communicatively coupled to the plurality of back end channels. The command queue is configured to hold host commands received from a host. Circuitry is configured to generate a number of back end commands at least in response to a number of the host commands in the command queue, and distribute the number of back end commands to a number of the plurality of back end channels.01-12-2012
20120324180MEMORY CONTROLLERS, MEMORY SYSTEMS, SOLID STATE DRIVES AND METHODS FOR PROCESSING A NUMBER OF COMMANDS - The present disclosure includes methods and devices for a memory controller. In one or more embodiments, a memory controller includes a plurality of back end channels, and a command queue communicatively coupled to the plurality of back end channels. The command queue is configured to hold host commands received from a host. Circuitry is configured to generate a number of back end commands at least in response to a number of the host commands in the command queue, and distribute the number of back end commands to a number of the plurality of back end channels.12-20-2012
20130013978DETERMINING SECTOR STATUS IN A MEMORY DEVICE - The present disclosure includes methods, devices, modules, and systems for operating semiconductor memory. A number of method embodiments include reading data from memory cells corresponding to a sector of data, determining a number of the memory cells in a non-erased state, and, if the number of the memory cells in a non-erased state is less than or equal to a number of errors correctable by an ECC engine, determining the sector is erased.01-10-2013
20130268701MEMORY CONTROLLERS, MEMORY SYSTEMS, SOLID STATE DRIVES AND METHODS FOR PROCESSING A NUMBER OF COMMANDS - The present disclosure includes methods and devices for a memory controller. In one or more embodiments, a memory controller includes a plurality of back end channels, and a command queue communicatively coupled to the plurality of back end channels. The command queue is configured to hold host commands received from a host. Circuitry is configured to generate a number of back end commands at least in response to a number of the host commands in the command queue, and distribute the number of back end commands to a number of the plurality of back end channels.10-10-2013
20140310431MEMORY CONTROLLERS, MEMORY SYSTEMS, SOLID STATE DRIVES AND METHODS FOR PROCESSING A NUMBER OF COMMANDS - The present disclosure includes methods and devices for a memory controller. In one or more embodiments, a memory controller includes a plurality of back end channels, and a command queue communicatively coupled to the plurality of back end channels. The command queue is configured to hold host commands received from a host. Circuitry is configured to generate a number of back end commands at least in response to a number of the host commands in the command queue, and distribute the number of back end commands to a number of the plurality of back end channels.10-16-2014

Patent applications by Yu-Song Liao, San Jose, CA US

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