Liang, MA
Dong-Yueh Liang, Sudbury, MA US
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20110200167 | RADIATION MODULATION IN A SECURITY EXAMINATION APPARATUS - Radiation flux can be adjusted “on the fly” as an object ( | 08-18-2011 |
Guiqing Liang, Concord, MA US
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20080269340 | BIS (thio-hydrazide amide) salts for treatment of cancers - Disclosed are bis(thio-hydrazide amide) disalts, which are represented by Structural Formula (I): | 10-30-2008 |
20090281172 | BIS(THIO-HYDRAZIDE AMIDE) SALTS FOR TREATMENT OF CANCERS - Disclosed are bis(thio-hydrazide amide) disalts, which are represented by Structural Formula (I): | 11-12-2009 |
20100324143 | BIS(THIO-HYDRAZIDE AMIDE) SALTS FOR TREATMENT OF CANCERS - Disclosed are bis(thio-hydrazide amide) disalts, which are represented by Structural Formula (I): | 12-23-2010 |
20120035266 | BIS(THIO-HYDRAZIDE AMIDE) SALTS FOR TREATMENT OF CANCERS - Disclosed are bis(thio-hydrazide amide) disalts and pharmaceutical compositions thereof. Also disclosed are methods of using bis(thio-hydrazide amide) disalts to treat cancer. | 02-09-2012 |
Huan Liang, Cambridge, MA US
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20150252007 | IODINE(III)-MEDIATED RADIOFLUORINATION - A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using | 09-10-2015 |
Jianglin Liang, Needham, MA US
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20100234423 | TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE - The present invention relates to compound 1, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising Compound 1 and methods of using the compositions in the treatment of proliferative disorders. | 09-16-2010 |
20110207774 | TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE - The present invention relates to compound 1, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising Compound 1 and methods of using the compositions in the treatment of proliferative disorders. | 08-25-2011 |
20110301195 | TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE - The present invention relates to compound 1, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising Compound 1 and methods of using the compositions in the treatment of proliferative disorders. | 12-08-2011 |
20140005192 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | 01-02-2014 |
Jin Liang, Southborough, MA US
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20100017124 | Location and path-map generation data acquisition and analysis systems - A device, system, and method for generating location and path-map data for displaying a location and path-map is disclosed. The device includes a first set of sensors for generating a plurality of first data signals with respect to an attitude of an object; a second set of sensors for generating a plurality of second data signals with respect to the attitude of the object; an imaging device for generating a plurality of third data signals that include a most significant feature, which is disposed in at least two images of the imaging device; and at least one processing device that is adapted to calculate a heading direction (bearing) of the device using the plurality of first data signals and the plurality of second data signals; to calculate a distance traveled along the heading direction using the plurality of third data signals; and to translate the calculated heading direction and calculated distance traveled into a leg or portion of a leg of a path-map for visual display on a two- or three-dimensional system. | 01-21-2010 |
20120111190 | AIR PURIFICATION AND DECONTAMINATION SYSTEM - A closed loop air handling system for monitoring and cleaning air from corrosive contaminants. Commonly occurring corrosive elements found in air can react in combination together and with other environmental conditions to increase the propensity for corrosion to occur. The higher corrosive level of air can react with metals causing degradation, wear and often lead to premature failure. This is especially prevalent in environments using forced air convection for cooling, such as data centers. The electronic circuitry is especially vulnerable to such corrosion and requires an environmentally controlled atmosphere with mild corrosiveness for long term reliability. The invention involves circulating the air in a closed loop and monitors and adjusts parameters of active filtration and purification to minimize corrosive agents. The system maintains a milder corrosive environment and better accommodates the use of “free cooling” from outside air for improved energy efficiency and lower carbon emissions. Air quality data is also collected and used to estimate equipment life time expectancy and substantiate warranty claims over exceeding manufacturers recommended environmental operating conditions. | 05-10-2012 |
Jinsheng Liang, Shrewsbury, MA US
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20150290204 | COMBINATION THERAPY - A pharmaceutical combination comprising (a) a compound of formula (I), | 10-15-2015 |
Kenneth K. Liang, Stow, MA US
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20130155812 | Using Higher Order Harmonics to Determine Acoustic Impedance of Material Behind Borehole Casings - An acoustic logging tool emits a wideband acoustic pulse toward an inside surface of a borehole casing and an acoustic response is received. The acoustic response is analyzed at one or more higher order harmonics of the thickness mode resonance of the casing to determine the acoustic impedance of the material behind the casing. | 06-20-2013 |
20140269165 | Using Higher Order Harmonics to Determine Acoustic Impedance of Material Behind Borehole Casings - An acoustic logging tool emits a wideband acoustic pulse toward an inside surface of a borehole casing and an acoustic response is received. The acoustic response is analyzed at one or more higher order harmonics of the thickness mode resonance of the casing to determine the acoustic impedance of the material behind the casing. | 09-18-2014 |
Lin Liang, Belmont, MA US
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20160033673 | ESTIMATING PETROPHYSICAL PARAMETERS AND INVASION PROFILE USING JOINT INDUCTION AND PRESSURE DATA INVERSION APPROACH - Methods and related systems are described relating to an inversion approach for interpreting the geophysical electromagnetic data. The inversion can be constrained by using a multiphase fluid flow simulator (incorporating pressure data if available) which simulates the fluid flow process and calculates the spatial distribution of the water saturation and the salt concentration, which are in turn transformed into the formation conductivity using a resistivity-saturation formula. In this way, the inverted invasion profile is consistent with the fluid flow physics and moreover accounts for gravity segregation effects. Jointly with the pressure data, the inversion estimates a parametric one-dimensional distribution of permeability and porosity. The fluid flow volume is directly inverted from the fluid-flow-constrained inversion of the electromagnetic data. The approach is not limited by the traditional interpretation of the formation test, which is based on a single-phase model without taking into account invasion or assuming that the fluid, for example mud-filtrate, has been cleaned up from the formation testing zone. The joint inversion of the electromagnetic and pressure data provides for a more reliable interpretation of formation permeability. One advantage of the approaches described herein, is its possible generalization to three-dimensional geometries, for example dipping beds and highly deviated wells. | 02-04-2016 |
Lin Liang, Cambridge, MA US
Patent application number | Description | Published |
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20100185393 | ESTIMATING PETROPHYSICAL PARAMETERS AND INVASION PROFILE USING JOINT INDUCTION AND PRESSURE DATA INVERSION APPROACH - Methods and related systems are described relating to an inversion approach for interpreting the geophysical electromagnetic data. The inversion can be constrained by using a multiphase fluid flow simulator (incorporating pressure data if available) which simulates the fluid flow process and calculates the spatial distribution of the water saturation and the salt concentration, which are in turn transformed into the formation conductivity using a resistivity-saturation formula. In this way, the inverted invasion profile is consistent with the fluid flow physics and moreover accounts for gravity segregation effects. Jointly with the pressure data, the inversion estimates a parametric one-dimensional distribution of permeability and porosity. The fluid flow volume is directly inverted from the fluid-flow-constrained inversion of the electromagnetic data. The approach is not limited by the traditional interpretation of the formation test, which is based on a single-phase model without taking into account invasion or assuming that the fluid, for example mud-filtrate, has been cleaned up from the formation testing zone. The joint inversion of the electromagnetic and pressure data provides for a more reliable interpretation of formation permeability. One advantage of the approaches described herein, is its possible generalization to three-dimensional geometries, for example dipping beds and highly deviated wells. | 07-22-2010 |
20150205002 | Methods for Interpretation of Time-Lapse Borehole Seismic Data for Reservoir Monitoring - A method for analyzing a reservoir parameter, the method including obtaining baseline borehole seismic (BHS) measurements and monitor BHS measurements, calculating, by a processor, a baseline velocity model from the baseline BHS measurements, calculating, by the processor, a monitor velocity model from the monitor BHS measurements, and determining a model change in the reservoir parameter by comparing the baseline velocity model and the monitor velocity model. | 07-23-2015 |
Li-Shiang Liang, Harvard, MA US
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20080237045 | INJECTION BONDED ARTICLES AND METHODS OF FABRICATION AND USE THEREOF - Injection bonded articles comprised of a rigid core and secured together with an elastomeric material network which also forms seals and encapsulates at least a portion of the rigid core. The elastomeric material is selected to be compatible with the material comprising the rigid core to create a chemical and mechanical bond therebetween. Injection bonding and over-molding techniques are used to fabricate an electrodeionization apparatus spacer comprised of mated rigid segments secured by a unitary elastomeric material network that also forms internal and external seals that fluidly isolate one or more of inlet ports, resin cavities, and outlet ports as well as throughports. Injection bonding and over-molding techniques can also be used to fabricate other articles comprised of multiple segments. | 10-02-2008 |
20100140095 | ON-DEMAND INTERMITTENT HIGH PURITY WATER PRODUCTION SYSTEM - An on-demand system for intermittent high purity water production which by locating a storage tank for pre-polished water just prior to a final high purity polishing device reduces the potential for stagnant water in the system to reduce or degrade product high purity water quality and reduces the actual degradation of high purity water quality. Pre-polished water is preferably produced by reverse osmosis. Final polished water is produced by continuous electrodeionization. | 06-10-2010 |
20100140153 | MANIFOLD BLOCK FOR REVERSE OSMOSIS SYSTEMS - Manifold blocks are preferably injection molded thermoplastic components of a pressurized membrane water treatment system, preferably a reverse osmosis system. A manifold block comprises a structural member of the system having at least one integral flow channel. Each channel has one or more fluidly interconnectable inlet ports and fluidly interconnectable outlet ports. The manifold block provides interconnection for modules and pumps and passageways for liquid transport. The novel manifold blocks described allow RO systems to be designed and fabricated with improved accessibility, ease of fabrication and modification in the field, and compact structure. | 06-10-2010 |
20100282689 | LOW ENERGY SYSTEM AND METHOD OF DESALINATING SEAWATER - A low energy water treatment system and method is provided. The system has at least one electrodialysis device that produces partially treated water and a brine byproduct, a softener, and at least one electrodeionization device. The partially treated water stream can be softened by the softener to reduce the likelihood of scale formation and to reduce energy consumption in the electrodeionization device, which produces water having target properties. At least a portion of the energy used by the electrodeionization device can be generated by concentration differences between the brine and seawater streams introduced into compartments thereof. The brine stream can also be used to regenerate the softener. | 11-11-2010 |
20110180477 | LOW ENERGY SYSTEM AND METHOD OF DESALINATING SEAWATER - A low energy system and process for seawater desalination wherein the system has at least an electrodialysis apparatus that produces partially desalinated water and a brine by-product, an ion exchange softener, and at least one electrodeionization apparatus. The softener treats the partially desalinated water stream to remove or reduce the amount of scaling material in order to maintain deionization apparatus efficiency and reduce energy consumption. The softener has the capability of removing a higher ratio of calcium ions to magnesium ions than is in the partially desalinated stream, thereby reducing softener size and energy use. The deionization apparatus produces product water of the desired properties. The brine stream may be used to regenerate the softener. | 07-28-2011 |
20110284376 | SYSTEMS AND TECHNIQUES FOR ELECTRODIALYSIS - Electrochemical separation devices are configured for lower energy consumption. Techniques for reducing shadow effect may involve providing distance between a spacer screen and an adjacent ion-selective membrane. A spacer having a screen that is thin relative to a surrounding frame may be used. Mild pressure may also be applied to a compartment to promote distance between a spacer screen and an adjacent ion-selective membrane. | 11-24-2011 |
20110303544 | APPARATUS FOR FLUID PURIFICATION AND METHODS OF MANUFACTURE AND USE THEREOF - The present invention generally relates to devices able to purify fluids electrically that are contained within pressure vessels, as well as to methods of manufacture and use thereof. Liquids or other fluids to be purified enter the purification device and, under the influence of an electric field, are treated to produce an ion-depleted liquid. Species from the entering liquids are collected to produce an ion-concentrated liquid. Increasing the exterior pressure on the device may reduce the pressure difference between the interior of the device and the exterior, which may reduce manufacturing costs or simplify construction. | 12-15-2011 |
20120117789 | Methods of Making a Cell Stack for an Electrical Purification Apparatus - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-17-2012 |
20120118728 | ELECTRICAL PURIFICATION APPARATUS HAVING A BLOCKING SPACER - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-17-2012 |
20120118729 | MODULAR ELECTROCHEMICAL SYSTEMS AND METHODS - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 05-17-2012 |
20120118730 | MODULAR ELECTROCHEMICAL SYSTEMS AND METHODS - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 05-17-2012 |
20120118731 | Flow Distributors for Electrochemical Separation - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 05-17-2012 |
20120118738 | METHOD OF PROVIDING A SOURCE OF POTABLE WATER - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-17-2012 |
20120118742 | Techniques for Promoting Current Efficiency in Electrochemical Separation Systems and Methods - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 05-17-2012 |
20120118743 | ELECTRICAL PURIFICATION APPARATUS - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-17-2012 |
20120118744 | ELECTROCHEMICAL SEPARATION MODULES - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 05-17-2012 |
20120199484 | ELECTRICAL PURIFICATION APPARATUS AND METHODS OF MANUFACTURING SAME - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to decreased residence times and higher purity water. | 08-09-2012 |
20130008791 | METHOD AND SYSTEM FOR IRRIGATION - An electrically-driven separation apparatus can be utilized to desalinate seawater and/or brackish water to provide irrigation water having a desired sodium adsorption ratio (SAR). | 01-10-2013 |
20130008858 | Systems and Methods for Process Stream Treatment - Systems and methods for process stream treatment. The treatment system may generally include an oxidation unit coupled to a downstream demineralization unit. The oxidation unit may oxidize organic and reduced sulfur contaminants in the process stream to facilitate downstream treatment. The demineralization unit may convert a product of the oxidation unit to generate a mineral stream. In some examples, the process stream may be a spent caustic stream from an industrial operation, such as an ethylene production facility or a petroleum refinery. A fresh caustic stream, such as a sodium hydroxide stream, may be isolated in the demineralization step and returned to the industrial operation for use. | 01-10-2013 |
20130015135 | METHOD AND SYSTEM FOR WATER TREATMENT - Water treatment systems including electrically-driven and pressure-driven separation apparatus configured to produce a first treated water suitable for use as irrigation water and a second treated water suitable for use as potable water from one of brackish water and seawater and methods of operation of same. | 01-17-2013 |
20130126355 | LOW SCALE POTENTIAL WATER TREATMENT - An electrochemical treating device having low scale potential is disclosed. The device has a variety of configurations directed to the layering of the anionic exchange and cationic exchange. The treatment device can also comprise unevenly sized ion exchange resin beads and/or have at least one compartment that provides a dominating resistance that results in a uniform current distribution throughout the apparatus. | 05-23-2013 |
20140115877 | METHODS OF MAKING A CELL STACK FOR AN ELECTRICAL PURIFICATION APPARATUS - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-01-2014 |
20140183045 | Electrodesalination System and Method - Systems and methods for the desalination of seawater or brackish water for the purpose of obtaining potable water. Systems may include a combination of electrodialysis and electrodeionization modules. The system configuration and process controls may achieve low energy consumption and stable operation. | 07-03-2014 |
20140216934 | ELECTROCHEMICAL DESALINATION FOR OIL RECOVERY - Electrically-driven separation systems and methods for use in oil recovery. | 08-07-2014 |
20150108007 | LOW ENERGY SYSTEM AND METHOD OF DESALINATING SEAWATER - A low energy water treatment system and method is provided. The system has at least one electrodialysis device that produces partially treated water and a brine byproduct, a softener, and at least one electrodeionization device. The partially treated water stream can be softened by the softener to reduce the likelihood of scale formation and to reduce energy consumption in the electrodeionization device, which produces water having target properties. At least a portion of the energy used by the electrodeionization device can be generated by concentration differences between the brine and seawater streams introduced into compartments thereof. The brine stream can also be used to regenerate the softener. | 04-23-2015 |
20150122657 | ELECTRICAL PURIFICATION APPARATUS HAVING A BLOCKING SPACER - An electrical purification apparatus and methods of making same are disclosed. The electrical purification apparatus may provide for increases in operation efficiencies, for example, with respect to current efficiencies and membrane utilization. | 05-07-2015 |
20150225268 | LOW SCALE POTENTIAL WATER TREATMENT - An electrochemical treating device having low scale potential is disclosed. The device has a variety of configurations directed to the layering of the anionic exchange and cationic exchange. The treatment device can also comprise unevenly sized ion exchange resin beads and/or have at least one compartment that provides a dominating resistance that results in a uniform current distribution throughout the apparatus. | 08-13-2015 |
20150299003 | ELECTRODESALINATION SYSTEM AND METHOD - Systems and methods for the desalination of seawater or brackish water for the purpose of obtaining potable water. Systems may include a combination of electrodialysis and electrodeionization modules. The system configuration and process controls may achieve low energy consumption and stable operation. | 10-22-2015 |
20150368125 | TECHNIQUES FOR PROMOTING CURRENT EFFICIENCY IN ELECTROCHEMICAL SEPARATION SYSTEMS AND METHODS - An electrochemical separation system may be modular and may include at least a first modular unit and a second modular unit. Each modular unit may include a cell stack and a frame. The frame may include a manifold system. A flow distribution system in the frame may enhance current efficiency. Spacers positioned between modular units may also enhance current efficiency of the system. | 12-24-2015 |
Rebecca Yue Liang, Cambridge, MA US
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20150225471 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS - Provided herein are stapled or stitched polypeptides comprising an alpha-helical segment, wherein the polypeptide binds to the insulin receptor, and wherein the polypeptide comprises at least two cross-linked amino acids as shown in Formula (iii), or at least three cross-linked amino acids as shown in Formula (iv). Further provided are pharmaceutical compositions comprising the stapled or stitched polypeptides, methods of use, e.g., methods of treating a diabetic condition or complications thereof. Precursor “unstapled” polypeptides useful in the preparation of stapled and stitched polypeptides are also described. | 08-13-2015 |
Tao Liang, Westford, MA US
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20080308306 | SHIFTED SEGMENT LAYOUT FOR DIFFERENTIAL SIGNAL TRACES TO MITIGATE BUNDLE WEAVE EFFECT - An article of manufacture includes a circuit board and a pair of traces on or in the circuit board. The pair of traces includes a first trace and a second trace. The first trace includes a first segment and a second segment continuously joined to the first segment. The first segment coincides with a first longitudinal axis. The second trace includes a first segment that runs alongside the first segment of the first trace. The second trace also includes a second segment that runs alongside the second segment of the first trace. The second segment of the second trace is continuously joined to the first segment of the second trace. The second segment of the second trace coincides with the first longitudinal axis. | 12-18-2008 |
20090079522 | COMPONENT-LESS TERMINATION FOR ELECTROMAGNETIC COUPLERS USED IN HIGH SPEED/FREQUENCY DIFFERENTIAL SIGNALING - Component-less termination for electromagnetic couplers used in high speed/frequency differential signaling is described. In one embodiment, the apparatus includes a first signal line and a second signal line forming a differential pair, a first electromagnetic coupler to provide sampled electromagnetic signals from the first signal line, and a second electromagnetic coupler to provide sampled electromagnetic signals from the second signal line, wherein the first electromagnetic coupler is far end short circuited and wherein the second electromagnetic coupler is far end open circuited. Other embodiments are also described and claimed. | 03-26-2009 |
20100202118 | SHIFTED SEGMENT LAYOUT FOR DIFFERENTIAL SIGNAL TRACES TO MITIGATE BUNDLE WEAVE EFFECT - An article of manufacture includes a circuit board and a pair of traces on or in the circuit board. The pair of traces includes a first trace and a second trace. The first trace includes a first segment and a second segment continuously joined to the first segment. The first segment coincides with a first longitudinal axis. The second trace includes a first segment that runs alongside the first segment of the first trace. The second trace also includes a second segment that runs alongside the second segment of the first trace. The second segment of the second trace is continuously joined to the first segment of the second trace. The second segment of the second trace coincides with the first longitudinal axis. | 08-12-2010 |
Xiangdong Liang, Cambridge, MA US
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20130202888 | In-Fiber Particle Generation - A fiber is provided, including a cladding material that is disposed along a longitudinal-axis fiber length. A plurality of spherical particles are disposed as a sequence along a longitudinal line parallel to the longitudinal fiber axis in at least a portion of the fiber length, and include a spherical particle material that is interior to the fiber cladding material and different than the fiber cladding material. To produce particles, a drawn fiber, having a longitudinal-axis fiber length and including at least one fiber core that has a longitudinal core axis parallel to the longitudinal fiber axis and that is internally disposed to at least one outer fiber cladding layer along the fiber length, is heated for a time that is sufficient to cause a fiber core to break-up into droplets sequentially disposed along the fiber core axis. Fiber cooling solidifies droplets into spherical particles interior to fiber cladding. | 08-08-2013 |
20150044463 | Dynamic In-Fiber Particle Production With Precise Dimensional Control - A fiber is provided that has been thermally drawn from a fiber preform, having a longitudinal-axis length and including at least one core that has a longitudinal core axis parallel to the longitudinal axis and internally disposed to at least one outer fiber cladding material layer along the fiber length. The fiber is fed through a localized heating site having a heating site temperature, T, that is above a melting temperature of the fiber core, with a feed speed, υ | 02-12-2015 |
Xiaoyao Liang, Cambridge, MA US
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20090134707 | Process Variation Tolerant Circuit With Voltage Interpolation And Variable Latency - A circuit having dynamically controllable power. The circuit comprises a plurality of pipelined stages, each of the pipelined stages comprising two clocking domains, a plurality of switching circuits, each switching circuit being connected to one of the pipelined stages, first and second power sources connected to each of the plurality of pipelined stages through the switching circuits, the first power source supplying a first voltage and the second power source supplying a second voltage, wherein the first and second power sources each may be applied to a pipelined stage independently of other pipelined stages, first and second complementary clocks, and a plurality of latches connected to the first and second complementary clocks and to the plurality of pipelined stages for proving latch-based clocking to control the first and second clocking domains and to enable time-borrowing across the plurality of switching circuits. The first voltage differs from the second voltage and the plurality of pipelined stages interpolates between the first and second voltages to provide differing effective voltages between the first and second voltages. | 05-28-2009 |
Xinghua Liang, Woburn, MA US
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20150372211 | LIGHT EMITTING DIODE PACKAGE - This application relates to a packaging structure, particularly to a light emitting diode package structure. | 12-24-2015 |
Yafen Liang, Quincy, MA US
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20100106037 | METHOD AND DEVICE FOR DETERMINING CARDIAC OUTPUT WITH CARBON DIOXIDE PARTIAL RE-BREATHING - A method and apparatus ( | 04-29-2010 |
Yue Liang, Cambridge, MA US
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20120270800 | BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF - The invention relates to bifunctional stapled or stiched peptides comprising a targeting domain, a linker moiety, and an effector domain, that can be used to tether, or to bring into close proximity, at least two cellular entities (e.g., proteins). Certain aspects relate to bifunctional stapled or stiched peptides that bind to an effector biomolecule through the effector domain and bind to a target biomolecule through the targeting domain. Polypeptides and/or polypeptide complexes that are tethered by the bifunctional stapled or stiched peptides of the invention, where the effector polypeptide bound to the effector domain of the bifunctional stapled or stiched peptide modifies or alters the target polypeptide bound to the targeting domain of the bifunctional peptide. Uses of the inventive bifunctional stapled or stiched peptides including methods for treatment of disease (e.g., cancer, inflammatory diseases) are also provided. | 10-25-2012 |