Patent application number | Description | Published |
20110231530 | PUBLISHING USER SUBMISSIONS AT A NETWORK-BASED FACILITY - According to the present invention, there is provided a method to facilitate propagating a plurality of transaction listings to a network-based transaction facility. An input interface is presented at a seller application to receive from a user, a plurality of transaction listings, each transaction listing including an associated start time. Also, a data file is composed at the seller application to include the plurality of transaction listings. Moreover, the data file is propagated, using the seller application, from the client computer to the network-based transaction facility. | 09-22-2011 |
20120047029 | Customizing an application - A system is configured to perform a method of customizing an application. The method includes receiving a connection from a client machine that is executing an application configurable by configuration information. The method also includes determining that the application has not been customized by the configuration information. The method further includes transmitting the configuration information to the client machine in response to the determining that the application has not been customized by the configuration information. In response to the transmitting of the configuration information, the application is configured to include a category structure for the application. In some example embodiments, the configuration information includes a software module upgrade of the application. | 02-23-2012 |
20120246233 | PUBLISHING USER SUBMISSIONS - According to the present invention, there is provided a method to facilitate propagating a plurality of transaction listings to a network-based transaction facility. An input interface is presented at a seller application to receive from a user, a plurality of transaction listings, each transaction listing including an associated start time. Also, a data file is composed at the seller application to include the plurality of transaction listings. Moreover, the data file is propagated, using the seller application, from the client computer to the network-based transaction facility. | 09-27-2012 |
20140324594 | METHOD AND SYSTEM FOR CUSTOMIZING A NETWORK-BASED TRANSACTION FACILITY SELLER APPLICATION - According to the present invention, there is provided a method of customizing a seller application that facilitates communication of listings to a network-based transaction facility. The method includes facilitating selection of at least one targeted site from a plurality of targeted sites presented to a user, wherein the plurality of targeted sites are supported by the network-based transaction facility. The method further includes configuring the seller application according to the at least one targeted site selected. | 10-30-2014 |
Patent application number | Description | Published |
20110096572 | LOW POWER CONSUMPTION START-UP CIRCUIT WITH DYNAMIC SWITCHING - A start-up circuit in a switch-mode power converter that employs a Zener diode to provide a reference voltage to reduce the power consumption and the size of the start-up circuit. The start-up circuit also includes a coarse current source and a coarse reference voltage signal generator for producing current and reference voltage for initial startup operation of a bandgap circuit. The reference signal and current from coarse current source and the reference voltage signal generator are subject to large process, voltage and temperature (PVT) variations or susceptible to noise from the power supply, and hence, these signals are used temporarily during start-up and replaced with signals from higher performance components. After bandgap circuit becomes operational, the start-up receives voltage reference signal from the bandgap circuit to more accurately detect undervoltage lockout conditions. | 04-28-2011 |
20120223648 | Adaptive Switch Mode LED System - A system that provides an intelligent approach to driving multiple strings of LEDs. A processing device determines an optimal current level for each LED string from a limited set of allowed currents. The processing device also determines a PWM duty cycle for driving the LEDs in each LED string to provide precise brightness control over the LED string. The settings for the current level and duty cycle are transmitted to an LED driver for regulating the current and on-off times of the LED strings. Beneficially, the system reduces the size of the LED driver while leveraging existing resources available in the processing device to operate the LEDs in a power efficient manner. | 09-06-2012 |
20130147374 | HIGH PERFORMANCE ADAPTIVE SWITCHED LED DRIVER - An LED driver controls current through an LED string. The LED driver generates a boosted PWM signal to drive a PWM transistor in the LED current path such that the PWM transistor maintains a substantially constant V | 06-13-2013 |
20130169172 | Predictive Control of Power Converter for LED Driver - A system controls a switching power converter to power LED strings using a predictive feedforward control mechanism. An LED controller determines programmed current levels and duty cycles for driving LED strings. The LED controller determines a predicted load for a subsequent cycle of a switching power converter driving the LED strings based on the programmed current levels and duty cycles. A power conversion controller uses the predicted load information to control switching of the switching power converter. This improves the dynamic response of the switching converter to changing load conditions, thereby improving overall power efficiency and performance of the system. | 07-04-2013 |
20140210365 | HIGH PERFORMANCE ADAPTIVE SWITCHED LED DRIVER - An LED driver controls current through an LED string. The LED driver generates a boosted PWM signal to drive a PWM transistor in the LED current path such that the PWM transistor maintains a substantially constant V | 07-31-2014 |
20150076999 | Modifying Duty Cycles of PWM Drive Signals to Compensate for LED Driver Mismatches in a Multi-Channel LED System - An LED (Light Emitting Diode) controller comprises a first LED driver to generate a first PWM (Pulse Width Modulation) drive signal to turn on or turn off, respectively, a first current through a first LED string. Additionally, the LED controller comprises a compensation circuit to generate the first PWM drive signal responsive to a first duty set signals. The first duty set signal is indicative of a first duty cycle set for the first PWM drive signal. The compensation circuit receives a first feedback signal indicative of the first current, generates a first error signal indicative of a difference between a first predetermined target value and the first feedback signal, and generates the first PWM drive signal to have the first duty cycle corresponding to the first duty set signal and further adjusted by the first error signal. | 03-19-2015 |
Patent application number | Description | Published |
20100297641 | METHYLATION ALTERED DNA SEQUENCES AS MARKERS ASSOCIATED WITH HUMAN CANCER - There is disclosed 103 novel methylation-altered DNA sequences (“marker sequences”) that have distinct methylation patterns in cancer, compared to normal tissue. In many instances, these marker sequences represent novel sequences not found in the GenBank data base, and none of these marker sequences have previously been characterized with respect to their methylation pattern in human cancers including, but not limited to those of bladder and prostate. These 103 sequences have utility as diagnostic, prognostic and therapeutic markers in the treatment of human cancer, and as reagents in kits for detecting methylated CpG-containing nucleic acids. | 11-25-2010 |
20110201103 | System For Synergetic Expression Of Multiple Small Functional RNA Elements - The present invention relates in general to microRNAs (miRNAs). More specifically, the invention relates to expression vectors comprising multiple miRNA families and clusters capable of targeting multiple oncogenic pathways. | 08-18-2011 |
20110224284 | PUTATIVE TUMOR SUPPRESSOR MICRORNA-101 MODULATES THE CANCER EPIGENOME BY REPRESSING THE POLYCOMB GROUP PROTEIN EZH2 - The present invention relates in general to microRNA profiling in disease. More specifically, the invention provides for methods and compositions of microRNA to inhibit the growth and formation of tumors. | 09-15-2011 |
20120028817 | Methods and Kits for Genome-Wide Methylation of GpC Sites and Genome-Wide Determination of Chromatin Structure - Disclosed are methods and kits for genome-wide methylation of GpC sites and for genome-wide chromatin structural determination. Specifically, the methods and kits of the present invention make possible the simultaneous determination of endogenous DNA methylation state and chromatin architecture across the entire genome. | 02-02-2012 |
20120208267 | System for Synergistic Expression of Multiple Small Functional RNA Elements - The present invention relates in general to microRNAs (miRNAs). More specifically, the invention relates to expression vectors comprising multiple miRNAs or families and, clusters capable of targeting multiple oncogenic pathways. | 08-16-2012 |
Patent application number | Description | Published |
20110286279 | Erase and Programming Techniques to Reduce the Widening of State Distributions in Non-Volatile Memories - Techniques are presented for use in memory devices to improve reliability and endurance by reducing the widening in state distributions, that occurs after multiple write/erase cycles. One set of techniques uses a pre-conditioning operation where a pulse series, which may include program and gentle erase, are applied to one or more wordlines while a voltage differential is applied in the wordline direction, bitline direction, or both. Another set of techniques uses a dual or multi-pulse program process, where an increased wordline-to-wordline differential used in the first pulse of a pair. | 11-24-2011 |
20120287716 | Using Channel-To-Channel Coupling To Compensate Floating Gate-To-Floating Gate Coupling In Programming Of Non-Volatile Memory - In a non-volatile storage system, during a verify operation, a verify voltage of a currently-sensed target data state is applied to a selected word line. A higher, nominal bit line voltage is used for the storage elements which have the currently-sensed target data state and a verify status of pass or no pass, a target data state lower than the currently-sensed target data state and a verify status of pass or no pass, or a target data state higher than the currently-sensed target data state and a verify status of pass. A lower bit line voltage is used for the storage elements which have the target data state higher than the currently-sensed target data state and a verify status of no pass, to enhance channel-to-channel coupling, as an offset to floating gate-to-floating gate coupling which is later caused by these storage elements. | 11-15-2012 |
20120300550 | Ramping Pass Voltage To Enhance Channel Boost In Memory Device, With Optional Temperature Compensation - In a non-volatile storage system, one or more substrate channel regions for an unselected NAND string are boosted during programming to inhibit program disturb. A voltage applied to one or more unselected word lines associated with at least a first channel region is increased during a program pulse time period in which a program pulse is applied to a selected word line. The increase can be gradual, in the form of a ramp, or step-wise. The boosting level of the first channel region can be maintained. The increase in the voltage applied to the one or more unselected word lines can vary with temperature as well. Before the program pulse time period, the voltage applied to the one or more unselected word lines can be ramped up at a faster rate for a second, adjacent channel region than for the first channel region, to help isolate the channel regions. | 11-29-2012 |
20130070531 | SUBSTRATE BIAS DURING PROGRAM OF NON-VOLATILE STORAGE - A programming technique which reduces program disturb in a non-volatile storage system is disclosed. A positive voltage may be applied to a substrate (e.g., p-well) during programming. Biasing the substrate may improve boosting of channels of unselected NAND strings, which may reduce program disturb. The substrate may be charged up during the programming operation, and discharged after programming. Therefore, for operations such as verify and read, the substrate may be grounded. In one embodiment, the substrate is charged just prior to applying a program pulse, then discharged prior to a program verify operation. In one embodiment, the substrate is charged while unselected word lines are ramped up to a pass voltage. The substrate bias may depend on program voltage, temperature, and/or hot count. | 03-21-2013 |
20130250688 | SELECTED WORD LINE DEPENDENT PROGRAMMING VOLTAGE - Methods and devices for operating non-volatile storage are disclosed. One or more programming conditions depend on the word line that is selected for programming. Applying a selected word line dependent program condition may reduce or eliminate program disturb. The duration of a programming pulse may depend on the word line that is selected for programming. This could be a physical characteristic of the word line or its location on a NAND string. As one example, a shorter pulse width may be used for the programming signal when programming edge word lines. | 09-26-2013 |
20130314987 | Ramping Pass Voltage To Enhance Channel Boost In Memory Device - In a non-volatile storage system, first and second substrate channel regions for an unselected NAND string are boosted during programming to inhibit program disturb. The first and second substrate channel regions are created on either side of an isolation word line. During a program pulse time period in which a program pulse is applied to a selected word line, a voltage applied to an unselected word line which extends directly over the second channel region is stepped up to a respective pre-program pulse voltage, at a faster rate at which a voltage applied to an unselected word line which extends directly over the first channel region is stepped up to a respective pre-program pulse voltage. This helps improve the isolation between the channel regions. | 11-28-2013 |
20140247663 | NON-VOLATILE STORAGE WITH PROCESS THAT REDUCES READ DISTURB ON END WORDLINES - A system for reducing read disturb on edge word lines in non-volatile storage is disclosed. In one embodiment, the memory cells on edge word lines are programmed using a series of pulses that have an initial magnitude and step size between pulses that are lower than for memory cells on word lines that are not edge word lines. Additionally, when reading memory cells on word lines that are not edge word lines, the edge word lines receive a lower pass voltage than the default pass voltage applied to other unselected word lines. In another embodiment, the system applies a higher than normal bias on a neighboring word lines when reading memory cells on an edge word line. | 09-04-2014 |
20140254262 | INTERNAL DATA LOAD FOR NON-VOLATILE STORAGE - Techniques are disclosed herein for performing an Internal Data Load (IDL) to sense non-volatile storage elements. Read pass voltages that are applied to the two neighbor word lines to a selected word line may be adjusted to result in a more accurate IDL. The read pass voltage for one neighbor may be increased by some delta voltage, whereas the read pass voltage for the other neighbor may be decreased by the same delta voltage. In one aspect, programming of an upper page of data into a word line that neighbors a target word line is halted to allow lower page data in the target memory cells to be read using an IDL and preserved in data latches while programming the upper page in the neighbor word completes. Preservation of the lower page data provides for a cleaner lower page when later programming the upper page into the target memory cells. | 09-11-2014 |
20140347925 | INTERNAL DATA LOAD FOR NON-VOLATILE STORAGE - Techniques are disclosed herein for performing an Internal Data Load (IDL) to sense non-volatile storage elements. Read pass voltages that are applied to the two neighbor word lines to a selected word line may be adjusted to result in a more accurate IDL. The read pass voltage for one neighbor may be increased by some delta voltage, whereas the read pass voltage for the other neighbor may be decreased by the same delta voltage. In one aspect, programming of an upper page of data into a word line that neighbors a target word line is halted to allow lower page data in the target memory cells to be read using an IDL and preserved in data latches while programming the upper page in the neighbor word completes. Preservation of the lower page data provides for a cleaner lower page when later programming the upper page into the target memory cells. | 11-27-2014 |
Patent application number | Description | Published |
20110220284 | Method for manufacturing tube mesh bag - The invention teaches a new way to make mesh bags using adhesive labels and continuous mesh tubing. Using adhesive labels on continuous mesh tubing is made possible by guiding the mesh tubing both on the outside of the tubing and the inside of the tubing so that an adhesive label does not stick to the mesh surface on the other side of the mesh tubing. As a result the invention also teaches a new type of mesh bag made with this process and a new machine used for making mesh bags. | 09-15-2011 |
20110222798 | Tube mesh bag - The invention teaches a new way to make mesh bags using adhesive labels and continuous mesh tubing. Using adhesive labels on continuous mesh tubing is made possible by guiding the mesh tubing both on the outside of the tubing and the inside of the tubing so that an adhesive label does not stick to the mesh surface on the other side of the mesh tubing. As a result the invention also teaches a new type of mesh bag made with this process and a new machine used for making mesh bags. | 09-15-2011 |
20120275729 | APPARATUS AND PROCESS FOR MANUFACTURING MESH BAGS FROM A ROLL OF MESH TUBE CLOTH - The present invention teaches a new apparatus and process for manufacturing mesh bags using a tube cloth. The apparatus and process involve supplying a continuous tube cloth and at least one band with preprinted labels, propping up the tube cloth with a dynamic guiding assembly, attaching the preprinted labels to the tube cloth using hot melted adhesive or heat sealing methods and manufacturing a product from the tube cloth with the horizontal preprinted labels, and attaching plastic film to the tube mesh cloth. The invention also teaches a dynamic guiding assembly which can be used to punch holes on the tube cloth with heating press and avoid attaching of two opposite sides of the tube cloth. | 11-01-2012 |
20140130958 | Process for Manufacturing Mesh Bags from a Roll of Continuous Mesh Tube - The present invention teaches a new process for manufacturing mesh bags using a tube cloth. The process involve supplying a continuous tube cloth and at least one band with preprinted labels, propping up the tube cloth with a dynamic guiding assembly, attaching the preprinted labels to the tube cloth using hot melted adhesive or heat sealing methods and manufacturing a product from the tube cloth with the horizontal preprinted labels, and attaching plastic film to the tube mesh cloth. | 05-15-2014 |
20140133784 | Mesh Bag Made from a Roll of Continuous Mesh Tube - The present invention teaches a new mesh bag made from a roll of continuous mesh tube cloth. The continuous tube cloth and at least one band with preprinted labels are used in a machine which props up the tube cloth with a dynamic guiding assembly, attaches the preprinted labels to the tube cloth using hot melted adhesive or heat sealing methods. The tube cloth is attached with the horizontal preprinted labels and the plastic film to the tube mesh cloth. A pair of holes are punched over the plastic film. | 05-15-2014 |
Patent application number | Description | Published |
20090093031 | Ketoreductase Polypeptides for the Production of (R)-3-Hydroxythiolane - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize chiral compounds. | 04-09-2009 |
20090155863 | KETOREDUCTASE POLYPEPTIDES AND USES THEREOF - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 06-18-2009 |
20090191605 | Ketoreductase Polypeptides for the Reduction of Acetophenones - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 07-30-2009 |
20100063300 | BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS - The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas, | 03-11-2010 |
20110217754 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize chiral compounds. | 09-08-2011 |
20120130087 | Stereomerically Pure Fused Bicyclic Proline Compounds Useful for Preparing Hepatitis C Protease Inhibitors - The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas, | 05-24-2012 |
20120184000 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (S,E)-METHYL 2-(3-(3-(2-(7-CHLOROQUINOLIN-2-YL)VINYL)PHENYL)-3-HYDROXYPROPYL)BENZOATE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 07-19-2012 |
20120244581 | Biocatalytic Processes for the Preparation of Stereomerically Pure Fused Bicyclic Proline Compounds - The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas, | 09-27-2012 |
20120276599 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize chiral compounds. | 11-01-2012 |
20120289709 | Substantially Stereomerically Pure Fused Bicyclic Proline Compounds and Processes for Preparing Boceprevir - The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas, | 11-15-2012 |
20130078692 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 03-28-2013 |
20130164794 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXAMINE - The disclosure provides transaminase polypeptides capable of converting the substrate, 2-(3,4-dimethoxyphenethoxy)cyclohexanone to the trans diastereomer product (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine in at least a 2:1 diastereomeric ratio relative to the cis diastereomer (1R,2S)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine. The disclosure also provides polynucleotides, vectors, host cells, and methods of making and using the transaminase polypeptides in processes for preparing (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine and its analogs, which can product compounds can be further used to prepare the aminocyclohexylether compound, (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol, which is an ion channel blocker. | 06-27-2013 |
20130344552 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 12-26-2013 |
20150017695 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 01-15-2015 |
Patent application number | Description | Published |
20120025289 | METAL CONTROL GATE FORMATION IN NON-VOLATILE STORAGE - Methods for fabricating control gates in non-volatile storage are disclosed. When forming stacks for floating gate memory cells and transistor control gates, a sacrificial material may be formed at the top of the stacks. After insulation is formed between the stacks, the sacrificial material may be removed to reveal openings. In some embodiments, cutouts are then formed in regions in which control gates of transistors are to be formed. Metal is then formed in the openings, which may include the cutout regions. Therefore, floating gate memory cells having at least partially metal control gates and transistors having at least partially metal control gates may be formed in the same process. A barrier layer may be formed prior to depositing the metal in order to prevent silicidation of polysilicon in the control gates. | 02-02-2012 |
20120187468 | METAL CONTROL GATE FORMATION IN NON-VOLATILE STORAGE - Methods for fabricating control gates in non-volatile storage are disclosed. When forming stacks for floating gate memory cells and transistor control gates, a sacrificial material may be formed at the top of the stacks. After insulation is formed between the stacks, the sacrificial material may be removed to reveal openings. In some embodiments, cutouts are then formed in regions in which control gates of transistors are to be formed. Metal is then formed in the openings, which may include the cutout regions. Therefore, floating gate memory cells having at least partially metal control gates and transistors having at least partially metal control gates may be formed in the same process. A barrier layer may be formed prior to depositing the metal in order to prevent silicidation of polysilicon in the control gates. | 07-26-2012 |
20130020708 | Copper Interconnects Separated by Air Gaps and Method of Making Thereof - A semiconductor device including a plurality of copper interconnects. At least a first portion of the plurality of copper interconnects has a meniscus in a top surface. The semiconductor device also includes a plurality of air gaps, wherein each air gap of the plurality of air gaps is located between an adjacent pair of at least the first portion of the plurality of bit lines. | 01-24-2013 |
20140008804 | COPPER INTERCONNECTS SEPARATED BY AIR GAPS AND METHOD OF MAKING THEREOF - A semiconductor device including a plurality of copper interconnects. At least a first portion of the plurality of copper interconnects has a meniscus in a top surface. The semiconductor device also includes a plurality of air gaps, wherein each air gap of the plurality of air gaps is located between an adjacent pair of at least the first portion of the plurality of bit lines. | 01-09-2014 |
Patent application number | Description | Published |
20120146146 | PARTIALLY DEPELETED (DP) SEMICONDUCTOR-ON-INSULATOR (SOI) FIELD EFFECT TRANSISTOR (FET) STRUCTURE WITH A GATE-TO-BODY TUNNEL CURRENT REGION FOR THRESHOLD VOLTAGE (Vt) LOWERING AND METHOD OF FORMING THE STRUCTURE - Disclosed are embodiments of a field effect transistor with a gate-to-body tunnel current region (GTBTCR) and a method. In one embodiment, a gate, having adjacent sections with different conductivity types, traverses the center portion of a semiconductor layer to create, within the center portion, a channel region and a GTBTCR below the adjacent sections having the different conductivity types, respectively. In another embodiment, a semiconductor layer has a center portion with a channel region and a GTBTCR. The GTBTCR comprises: a first implant region adjacent to and doped with a higher concentration of the same first conductivity type dopant as the channel region; a second implant region, having a second conductivity type, adjacent to the first implant region; and an enhanced generation and recombination region between the implant regions. A gate with the second conductivity type traverses the center portion. | 06-14-2012 |
20140117450 | PARTIALLY DEPLETED (PD) SEMICONDUCTOR-ON-INSULATOR (SOI) FIELD EFFECT TRANSISTOR (FET) STRUCTURE WITH A GATE-TO-BODY TUNNEL CURRENT REGION FOR THRESHOLD VOLTAGE (Vt) LOWERING AND METHOD OF FORMING THE STRUCTURE - Disclosed are embodiments of a field effect transistor with a gate-to-body tunnel current region (GTBTCR) and a method. In one embodiment, a gate, having adjacent sections with different conductivity types, traverses the center portion of a semiconductor layer to create, within the center portion, a channel region and a GTBTCR below the adjacent sections having the different conductivity types, respectively. In another embodiment, a semiconductor layer has a center portion with a channel region and a GTBTCR. The GTBTCR comprises: a first implant region adjacent to and doped with a higher concentration of the same first conductivity type dopant as the channel region; a second implant region, having a second conductivity type, adjacent to the first implant region; and an enhanced generation and recombination region between the implant regions. A gate with the second conductivity type traverses the center portion. | 05-01-2014 |
Patent application number | Description | Published |
20110220401 | LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY - A curing agent for epoxy resins that is comprised of the reaction product of an amine, an epoxy resin, and an elastomer-epoxy adduct; compositions containing the curing agent and an epoxy resin; the compositions are useful in electronic displays, circuit boards, semi conductor devices, flip chips and other applications. | 09-15-2011 |
20120007259 | LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY - A curing agent for epoxy resins that is comprised of the reaction product of an amine, an epoxy resin, and an elastomer-epoxy adduct; compositions containing the curing agent and an epoxy resin; the compositions are useful in electronic displays, circuit boards, semi conductor devices, flip chips and other applications. | 01-12-2012 |
20130295381 | LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY - A curing agent for epoxy resins that is comprised of the reaction product of an amine, an epoxy resin, and an elastomer-epoxy adduct; compositions containing the curing agent and an epoxy resin; the compositions are useful in electronic displays, circuit boards, semi conductor devices, flip chips and other applications. | 11-07-2013 |
Patent application number | Description | Published |
20110076550 | BATTERY WITH PROTECTIVE PACKAGING - A battery comprises at least one battery cell on a support, the battery cell comprising a plurality of electrodes about an electrolyte, and having a surface. A thermoplastic material covers the surface of the battery cell, the thermoplastic material comprising a nitrogen permeability or oxygen permeability that is less than 20 cm | 03-31-2011 |
20130098532 | THIN FILM BATTERY PACKAGING FORMED BY LOCALIZED HEATING - A battery packaging method comprises providing a battery comprising at least one battery cell on a substrate, the battery cell comprising a plurality of electrodes about an electrolyte, and the battery having at least one open peripheral side surface. A thermoplastic bead is provided at an open peripheral side surface of the battery. A cap is placed over the battery and in contact with the thermoplastic bead. The thermoplastic bead is locally heated by directing an energy beam onto the thermoplastic bead, the energy beam having a beam width sized sufficiently small to heat a beam incident region on the thermoplastic bead substantially without heating adjacent regions. | 04-25-2013 |
20130164459 | SPUTTERING LITHIUM-CONTAINING MATERIAL WITH MULTIPLE TARGETS - A method of depositing lithium-containing films on a battery substrate in a sputtering chamber is provided. At least one pair of sputtering targets that each comprise a lithium-containing sputtering member is provided in the sputtering chamber, the sputtering targets selected to each have a conductivity of at least about 5×10 | 06-27-2013 |
20130164607 | LAMINATED LITHIUM BATTERY - A lithium battery comprises at least one battery cell on a support, the battery cell comprising a plurality of electrodes about an electrolyte. A protective casing comprises a cover spaced apart from and covering the battery cell to form a gap therebetween with a polymer filling the gap. In one version, the polymer comprises polyvinylidene chloride polymer. First and second terminals extend out of the protective casing, the first and second terminals being connected to different electrodes of the battery cell. | 06-27-2013 |
20130260230 | LOCALIZED HEAT TREATMENT OF BATTERY COMPONENT FILMS - A battery fabrication method includes forming on a substrate, at least a portion of a battery cell having a plurality of battery component films that include an underlying film with an overlying metal-containing film. A beam incident area of the metal-containing film is locally heated by directing onto the metal-containing film, an energy beam maintained at a fluence of at least about 800 J/cm | 10-03-2013 |
20140087092 | PLASMA DEPOSITION ON A PARTIALLY FORMED BATTERY THROUGH A MESH SCREEN - A plasma deposition method deposits a battery component material on a partially fabricated battery cell comprising a battery component layer containing charge-carrying metal species and having an exposed surface. A mesh screen is maintained at a preset distance from the exposed surface, the mesh screen having a plurality of mesh openings. A process gas is energized to form a plasma by applying an electrical power to deposit the battery component material onto the exposed surface of the battery component layer. The mesh screen reduces migration of the charge-carrying metal species in the battery component layer to the exposed surface of the partially fabricated battery cell. | 03-27-2014 |
20140106203 | LITHIUM BATTERY HAVING LOW LEAKAGE ANODE - A lithium battery comprises a support, and a plurality of battery component layers on the support, the battery component layers including a cathode having a cathode area with a plurality of cathode perimeter edges. An electrolyte is on the cathode, and an anode is on the electrolyte. The anode comprises an anode area with a plurality of anode perimeter edges, each anode perimeter edge having a corresponding cathode perimeter edge that lies adjacent to and below the anode perimeter edge. The anode area is sized so that at least one anode perimeter edge is terminated before its corresponding cathode perimeter edge to define a gap between the anode perimeter edge and the corresponding cathode perimeter edge, the gap having a gap distance G. | 04-17-2014 |
20140106216 | THIN FILM BATTERY AND LOCALIZED HEAT TREATMENT - A lithium battery comprises a battery support and a cathode current collector directly on and in contact with the battery support. The cathode current collector is composed of molybdenum and comprises a thickness of at least about 0.01 microns. A cathode is on the cathode current collector, an electrolyte on the cathode, and at least one of an anode or anode current collector on the electrolyte. | 04-17-2014 |
20140291144 | PLASMA DEPOSITION ON A PARTIALLY FABRICATED BATTERY CELL THROUGH A MESH SCREEN - A plasma chamber for depositing a battery component material on a partially fabricated battery cell comprising a battery component layer containing charge-carrying metal species and having an exposed surface. The chamber comprises a support carrier to hold a battery support comprising the partially fabricated battery cell. A mesh screen is positioned at a preset distance from the support carrier, the mesh screen having a plurality of mesh openings. An exhaust maintains a pressure of the process gas in the plasma chamber. A plasma power source is capable of applying an electrical power to the process gas to generate a plasma from the process gas for plasma deposition, during which the mesh screen is capable of reducing migration of the charge-carrying metal species across the battery component layer. | 10-02-2014 |
Patent application number | Description | Published |
20110145704 | PROVIDING MULTIPLE VIEWS OF A BUSINESS PROCESS DEFINITION TO DIFFERENT VIEWS - In one embodiment, a method for providing multiple views of a business process definition includes storing a model of a business process, and providing different view points of the model to different classes of users. | 06-16-2011 |
20110202473 | Progressive Refinement Model for Business Processes - In one embodiment, a method for refining a business process model includes receiving business process data pertaining to a first phase of a business process definition from a first class of users, creating a model of a business process using the business process data received from the first class of users, receiving business process data pertaining to a second phase of the business process definition from a second class of users, and augmenting the model of the business process based on the business process data received from the second class of users. The method further includes iteratively refining the model of the business process in response to input provided by the first class of users and/or the second class of users. | 08-18-2011 |
20120005116 | MODELING OF BUSINESS PROCESS DATA - In one embodiment, a business process meta-model is defined that represents a business process. The business process meta-model includes control flow elements pertaining to a control flow of the business process, and annotation elements providing details for the control flow elements. | 01-05-2012 |
20120185821 | PATTERN-BASED CONSTRUCTION AND EXTENSION OF ENTERPRISE APPLICATIONS IN A CLOUD COMPUTING ENVIRONMENT - Methods, software programs and systems for extending and modifying software functionality, and, more particularly, for using one or more patterns for an enterprise software object to express desired functionality and configuration, and to generate the enterprise software object using the patterns, in an enterprise environment are disclosed. A method according to certain of these embodiments includes selecting one or more patterns from a number of patterns, where the one or more patterns are for an enterprise software object. The enterprise software object can then be generated. The enterprise software object is generated using the one or more patterns. Each of the patterns is configured to describe a solution within a corresponding one of a number of problem domains. | 07-19-2012 |
20140310055 | Progressive Refinement Model for Business Processes - In one embodiment, a method for refining a business process model includes receiving business process data pertaining to a first phase of a business process definition from a first class of users, creating a model of a business process using the business process data received from the first class of users, receiving business process data pertaining to a second phase of the business process definition from a second class of users, and augmenting the model of the business process based on the business process data received from the second class of users. The method further includes iteratively refining the model of the business process in response to input provided by the first class of users and/or the second class of users. | 10-16-2014 |
Patent application number | Description | Published |
20110274696 | ANTIBODIES TO CCR2 - Provided are antibodies including human antibodies and antigen-binding portions thereof that specifically bind to CCR2, specifically human CCR2, and that may function to inhibit CCR2. Anti-CCR2 antibodies include those which bind to the first and/or second extracellular loops of CCR2. Also provided are human anti-CCR2 antibodies and antigen-binding portions thereof. Isolated heavy and light chain immunoglobulins derived from human anti-CCR2 antibodies and nucleic acid molecules encoding such immunoglobulins are provided. Methods of making human anti-CCR2 antibodies or antigen-binding portions, compositions comprising these antibodies or antigen-binding portions, methods of using the antibodies and antigen-binding portions, and compositions for diagnosis and treatment are provided. Also provided are gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-CCR2 antibodies or antigen binding portions thereof | 11-10-2011 |
20130022597 | Antibodies Directed To GPNMB And Uses Thereof - The present invention provides fully human monoclonal antibodies that specifically bind to GPNMB, and uses thereof. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs) are provided. The present invention also provides immunoconjugates comprising anti-GPNMB antibodies and methods of using such immunoconjugates. The present invention further provides bi-specific antibodies comprising an anti-GPNMB antibody component and an anti-CD3 component, and methods of using such bispecific antibodies. | 01-24-2013 |
20150044212 | Antibodies Directed to GPNMB and Uses Thereof - The present invention provides fully human monoclonal antibodies that specifically bind to GPNMB, and uses thereof. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs) are provided. The present invention also provides immunoconjugates comprising anti-GPNMB antibodies and methods of using such immunoconjugates. The present invention further provides bi-specific antibodies comprising an anti-GPNMB antibody component and an anti-CD3 component, and methods of using such bispecific antibodies. | 02-12-2015 |
Patent application number | Description | Published |
20120100867 | Determining Points of Interest of a Mobile User - Methods, systems and apparatus for tracking points of interest of a user of a mobile device are disclosed. One method includes determining points of interest of a user of a mobile device. The method includes obtaining user-related information, wherein the user-related information includes spatial information about the user, and determining at least one point of interest of the user based on the user-related information. Another embodiment includes an apparatus for determining points of interest of a user. For one embodiment, the apparatus is a mobile device. The mobile device is operative to obtain user-related information, wherein the user-related information comprising spatial information about the user, and the mobile device is operative to determine at least one point of interest of the user based on the user-related information. | 04-26-2012 |
20120100869 | Location Based User Behavior Analysis and Applications - Methods, systems and apparatuses for generating a user profile of a mobile device user are disclosed. One method includes tracking user stays of the user over time, wherein the user stays include at least one location, and generating the user profile based at least in part on at least one of an arrival time, a time duration or a frequency of visits of the user at each of the user stays. Another method includes determining a current state of a mobile device user. The method includes tracking locations of user stays of the mobile device user over time, and determining a current state of a mobile device user based on user stays within a predetermined time of a present time, wherein the predetermined time is dependent upon an application of the user device or an observed behavior of a user of the user device. | 04-26-2012 |
20130102268 | CONTROLLING OPERATIONAL STATES OF A LOCATION SENSING SYSTEM OF A MOBILE DEVICE - Methods, systems and apparatuses for controlling a location sensing system of a mobile device are disclosed. One method includes collecting location related information of the mobile device. The method further includes controllably setting the mobile device to operate in one of a high-power state, a low-power state, or a transitional state based on the collected location related information, wherein a satellite-based positioning system receiver of the mobile device generates location information in the transitional state and in the on-state, and the satellite-based positioning system receiver does not generate location information in the low-power state. When operating in the transitional state, the mobile device repeatedly checks the collected location related information and transitions to the low-power state or the high-power state based on the collected location related information. | 04-25-2013 |
20130102283 | MOBILE DEVICE USER BEHAVIOR ANALYSIS AND AUTHENTICATION - Methods, systems and apparatuses for authenticating a user of a mobile device are disclosed. One method includes tracking a plurality of locations of the mobile device, tracking motion behavior of the mobile device, and generating a user profile for the user over a period of time based on the tracked plurality of locations and the tracked motion behavior. A present user of the mobile device is authenticated based on a comparison of the user profile with a present user profile of the present user, wherein the present user profile comprises recent location information of the mobile device and recent motion behavior of the mobile device. | 04-25-2013 |
20130252633 | DETERMINING USER STAYS OF A USER OF A MOBILE DEVICE - Methods, systems and apparatuses for automatically determining user stays of a user of a mobile device are disclosed. One embodiment includes a network server operative to receive sensed location information of a mobile device. Further, the network server and/or a controller of the mobile device are operative to determine the mobile device is within a specific distance of a specific location for at least specific minimum time duration based on the location information, determine a start time of a user stay based on the location information, the specific location and the specific distance, and determine an end time of the user stay based on the location information, the specific location and the specific distance. | 09-26-2013 |
20130252638 | Real-Time Determination of User Stays of a Mobile Device - Methods, systems and apparatuses for real-time determination of user stays of a mobile device are disclosed. One computer-implemented method includes receiving, by a server, an incoming stream of location point information of the mobile device. Further, the method includes continuously calculating, by the server, a current centroid of a current user stay based on a location point of a start time of the current user stay, each location point occurring between the start time and a current incoming location point, until an outlier location point is detected, wherein the outlier is detected if located more than a threshold distance away from the current centroid. | 09-26-2013 |
20130262479 | POINTS OF INTEREST (POI) RANKING BASED ON MOBILE USER RELATED DATA - Methods, systems and apparatus for ranking potential points of interest (POIs) of a user stay are disclosed. One system includes an upstream server connected through a network to a mobile device. At least one of the upstream server and a controller of the mobile device is operative to estimate a location of a user stay of the mobile device, access a database of POIs, and parameters of the POIs, and generate a ranking score for a plurality of POIs based on a weighted comparison of each of the parameters of the POIs with corresponding parameters of the user stay. | 10-03-2013 |
20130267255 | IDENTIFY POINTS OF INTEREST USING WIRELESS ACCESS POINTS - Methods, systems and apparatuses for using wireless access points to identify points of interest (POIs), are disclosed. One embodiment includes a method of using wireless access points to identify points of interest (POIs). The method includes collecting wireless access data points, wherein the wireless access data points comprise at least one wireless access point signature of at least one wireless access element of the wireless access points, analyzing the wireless access data points over a time window, comprising identifying segments within the time window, and matching a point of interest (POI) with each identified segment. | 10-10-2013 |
20130324196 | CONTROL OF ACTIVATION OF LOCATION-RELATED SENSORS OF A MOBILE DEVICE - Methods, systems and apparatuses for selecting which of a plurality of sensors to use for location detection of a mobile device are disclosed. One method includes activating lowest-power location-related sensors of the mobile device at power up of a mobile device, and activating medium-power location-related sensors of the mobile device upon detection of motion of the mobile device and/or a change in a wireless connection to the mobile device. | 12-05-2013 |
Patent application number | Description | Published |
20080241130 | METHODS AND COMPOSITIONS FOR MODULATING IL-17F/IL-17A BIOLOGICAL ACTIVITY - The invention provides a novel mouse IL-17F/IL-17A, and further provides uses of such mouse IL-17F/IL-17A in the characterization of the IL-17F/IL-17A heterodimer. The present invention is also related to polynucleotides and polypeptides of the IL-17F/IL-17A signaling pathway, and targeting of the IL-17F/IL-17A signaling pathway in methods of treating IL-17F/IL-17A-associated disorders. The invention thus provides methods of using isolated IL-17F/IL-17A heterodimer, e.g., in a mouse model of airway inflammation, and specific or selective IL-17F/IL-17A modulators (e.g., signaling agonists or signaling antagonists (e.g., specific or selective antagonistic antibodies, specific or selective antagonistic small molecules, etc.)). The invention also provides methods of screening for compounds capable of modulating IL-17F/IL-17A biological activity, e.g., IL-17F/IL-17A signaling antagonists (e.g., using the mouse model of airway inflammation), as well as methods of identifying whether the IL-17F/IL-17A modulator is a specific IL-17F/IL-17A modulator. The invention is also directed to novel methods for diagnosing, prognosing, monitoring, preventing, and/or treating IL-17F/IL-17A-associated disorders, including, but not limited to, inflammatory disorders (e.g., arthritis (including rheumatoid arthritis), psoriasis, systemic lupus erythematosus, and multiple sclerosis), respiratory diseases (e.g., airway inflammation, chronic obstructive pulmonary disease, cystic fibrosis, asthma, allergy), transplant rejection (including solid organ transplant rejection), and inflammatory bowel diseases or disorders (e.g., ulcerative colitis, Crohn's disease). The present invention is further directed to novel therapeutics and therapeutic targets identified by methods of screening of the invention, and uses of such identified therapeutics in methods of treatment and prevention of IL-17F/IL-17A-associated disorders. | 10-02-2008 |
20110212099 | METHODS OF MODULATING IL-22 AND IL-17 - The present application provides methods of modulating immune responses by using IL-22 in combination with at least one of IL-17A, IL-17F, or IL-23 or by using an IL-22 antagonist, such as an antibody or a soluble receptor or a binding protein, in combination with an antagonist of at least one of IL-17A, IL-17F, or IL-23 | 09-01-2011 |
Patent application number | Description | Published |
20090098112 | NOVEL ANTIBODIES - The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them. | 04-16-2009 |
20100172921 | INHIBITION OF TUMOR METASTASIS BY ANTI NEUROPILIN 2 ANTIBODIES - The application provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis. | 07-08-2010 |
20100189719 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 07-29-2010 |
20100260782 | NOVEL ANTI- Alpha 5 Beta 1 ANTIBODIES AND USES THEREOF - The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies. | 10-14-2010 |
20110014198 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 01-20-2011 |
20110020346 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 01-27-2011 |
20110142859 | ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR - Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. | 06-16-2011 |
20120100159 | ANTI-TAT226 ANTIBODIES AND IMMUNOCONJUGATES - Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided. | 04-26-2012 |
20120148572 | NOVEL ANTIBODIES - The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them. | 06-14-2012 |
20120156129 | NOVEL ANTIBODIES - The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them. | 06-21-2012 |
20120322982 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 12-20-2012 |
20120329094 | Anti-CD22 Antibodies And Immunoconjugates and Methods of Use - Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. | 12-27-2012 |
20130095096 | NOVEL ANTI- ALPHA5BETA1 ANTIBODIES AND USES THEREOF - The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies. | 04-18-2013 |
20130129743 | ANTI-HtrA1 ANTIBODIES AND METHODS OF USE - The invention provides anti-HtrA1 antibodies and methods of using the same. | 05-23-2013 |
20130156693 | ANTI-TAT226 ANTIBODIES AND IMMUNOCONJUGATES - Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided. | 06-20-2013 |
20130171170 | ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR - Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. | 07-04-2013 |
20130266581 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 10-10-2013 |
20130315918 | ANTI-VEGF ANTIBODIES - Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications. | 11-28-2013 |
20130336885 | ANTI-LGR5 ANTIBODIES AND IMMUNOCONJUGATES - The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same. | 12-19-2013 |
20140127197 | Anti-CD22 Antibodies and Immunoconjugates and Methods of Use - Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. | 05-08-2014 |
20140234312 | INHIBITION OF TUMOR METASTASIS - The invention provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis. | 08-21-2014 |
20140322129 | ANTI-B7-H4 ANTIBODIES AND IMMUNOCONJUGATES - The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same. | 10-30-2014 |
20140377860 | Anti-Bv8 Antibodies and Uses Thereof - The present invention concerns antibodies to Bv8 and the uses of same. | 12-25-2014 |
Patent application number | Description | Published |
20080260763 | High Throughput Proteomics - Methods to obtain expression systems and proteins in a high-throughput protocol by utilizing mixtures of cells cultured from those transformed with a desired nucleotide sequence permit rapid production of protein for use in arrays to assess activity. In one embodiment, the proteins (or peptides) in the array are assessed for their immunological activity with regard to an infectious agent. | 10-23-2008 |
20090285847 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 11-19-2009 |
20100119535 | COMPOSITIONS AND METHODS FOR IMMUNODOMINANT ANTIGENS - Contemplated compositions, devices, and methods comprise immunodominant antigens from selected human pathogens ( | 05-13-2010 |
20110245099 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 10-06-2011 |
20120142555 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 06-07-2012 |
20130072398 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 03-21-2013 |
20130310266 | Methods and Compositions For The Diagnosis And Treatment Of Cancer and Autoimmune Disorders - Compositions, devices, and methods are contemplated for predicting a patient's likelihood of having a disease. An antigen composition can have a plurality of autoantibody reactive antigens associated with a carrier, where at least two of the antigens have quantified and known relative autoantibody reactivities with respect to sera of a population affected by a disease. The at least two antigens can also have a known association with a disease parameter. A method can include determining autoantibody reactivity against one or more antigens or their variants in a serum sample obtained from a patient, where the autoantibody reactivity against one or more of the antigens indicates an increased likelihood of the patient having a disease. | 11-21-2013 |
20140004141 | Methods And Compositions Of Protein Antigens For The Diagnosis And Treatment Of Toxoplasma Gondii Infections And Toxoplasmosis | 01-02-2014 |
20140348870 | IMMUNOGENIC PLASMODIUM FALCIPARUM ANTIGEN COMPOSITIONS AND USES THEREOF - Contemplated compositions and methods employ selected antigens form | 11-27-2014 |
20150037367 | Methods and Compositions Of Protein Antigens For The Diagnosis And Treatment of Herpes Simplex Viruses Type 1 and 2 - Contemplated compositions, devices, and methods are drawn to various antigens from Herpes Simplex Virus type 1 (HSV-1) and Herpes Simplex Virus type 2 (HSV-2) and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter. | 02-05-2015 |
20150056241 | Compositions And Methods For Immunodominant Antigens - Contemplated compositions, devices, and methods comprise immunodominant antigens from selected human pathogens ( | 02-26-2015 |
Patent application number | Description | Published |
20110226942 | COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY - The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant proteins of the invention display high purities, making them suitable for use in mass spectrometry. | 09-22-2011 |
20110262947 | Isotopically-Labeled Proteome Standards - The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis. | 10-27-2011 |
20120205592 | COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY - The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant proteins of the invention display high purities, making them suitable for use in mass spectrometry. | 08-16-2012 |
20120258877 | IDENTIFICATION OF CANCER BIOMARKERS AND PHOSPHORYLATED PROTEINS - Methods are provided for identifying proteins that are differentially expressed in disease state and normal cells. Stable isotope labeling of cells in culture allows for the identification of a multiplicity of proteins whose differential abundance in normal and disease state cells can be indicative of the disease state. Biomarkers are identified for breast cancer, in which the biomarkers are proteins having a two-fold or greater difference in abundance between breast cancer and normal cells. Identified biomarkers can be used detection methods that can provide diagnosis, typing, staging, or prognosis of cancer, such as breast cancer, or can be used to predict the response of cancer, such as breast cancer, to one or more anti-cancer agents. | 10-11-2012 |
20140065625 | Isotopically-Labeled Proteome Standards - The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis. | 03-06-2014 |