Li, NC
Bochong Li, Durham, NC US
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20120059347 | PLUNGER CONTROL DEVICE FOR A SYRINGE AND ASSOCIATED METHOD - An apparatus and associated method are provided for controlling the plunging action of a syringe. A plunger control device includes an attachment member adapted to fixedly engage a syringe barrel. A translating member is slideably engaged with the attachment member. The translating member includes an elongate guide member slideably engaged with the attachment member such that the translating member is slideable with respect thereto between a proximal end and a distal end of the elongate guide member. The translating member further includes a plunger attachment portion disposed about the distal end of the elongate guide member and adapted to receive a portion of a syringe plunger for coupling thereto. The translating member further includes an engagement member extending from the proximal end of the elongate guide member so as to be spaced-apart from the syringe barrel when the attachment member is engaged with the syringe barrel. | 03-08-2012 |
Chenghong Li, Cary, NC US
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20080200011 | HIGH-TEMPERATURE, SPIN-ON, BONDING COMPOSITIONS FOR TEMPORARY WAFER BONDING USING SLIDING APPROACH - New compositions and methods of using those compositions as bonding compositions are provided. The compositions comprise a polymer dispersed or dissolved in a solvent system, and can be used to bond an active wafer to a carrier wafer or substrate to assist in protecting the active wafer and its active sites during subsequent processing and handling. The compositions form bonding layers that are chemically and thermally resistant, but that can also be softened to allow the wafers to slide apart at the appropriate stage in the fabrication process. | 08-21-2008 |
20090176106 | METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF - In accordance with the present invention, compositions are described which are useful, for example, for the preparation of metal-clad laminate structures, methods for the preparation thereof, and various uses therefor. Invention metal-clad laminate structures are useful, for example, multi-layer board (MLB) industry, in the preparation of burn-in test boards and high reliability boards, applications where low coefficient of thermal expansion (CTE) is beneficial, in the preparation of boards used in down-hole drilling, and the like. | 07-09-2009 |
20090176918 | METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF - In accordance with the present invention, compositions are described which are useful, for example, for the preparation of metal-clad laminate structures, methods for the preparation thereof, and various uses therefor. Invention metal-clad laminate structures are useful, for example, multi-layer board (MLB) industry, in the preparation of burn-in test boards and high reliability boards, applications where low coefficient of thermal expansion (CTE) is beneficial, in the preparation of boards used in down-hole drilling, and the like. | 07-09-2009 |
20100206479 | HIGH-TEMPERATURE, SPIN-ON, BONDING COMPOSITIONS FOR TEMPORARY WAFER BONDING USING SLIDING APPROACH - New compositions and methods of using those compositions as bonding compositions are provided. The compositions comprise a polymer dispersed or dissolved in a solvent system, and can be used to bond an active wafer to a carrier wafer or substrate to assist in protecting the active wafer and its active sites during subsequent processing and handling. The compositions form bonding layers that are chemically and thermally resistant, but that can also be softened to allow the wafers to slide apart at the appropriate stage in the fabrication process. | 08-19-2010 |
20100291475 | Silicone Coating Compositions - The present Invention relates to a novel polymer comprising a unit | 11-18-2010 |
Chengwen Li, Chapel Hill, NC US
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20080269149 | Chimeric Vectors - The present invention is based, in part, on the discovery that parvovirus (including AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases as little as a single amino acid insertion or substitution from a first parvovirus (e.g., an AAV) into the capsid structure of another parvovirus (e.g., an AAV) to create a chimeric parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus and/or to confer a property that is not exhibited by the first parvovirus or is present to a lesser extent. | 10-30-2008 |
20110104119 | Chimeric Vectors - The present invention is based, in part, on the discovery that parvovirus (including AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases as little as a single amino acid insertion or substitution from a first parvovirus (e.g., an AAV) into the capsid structure of another parvovirus (e.g., an AAV) to create a chimeric parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus and/or to confer a property that is not exhibited by the first parvovirus or is present to a lesser extent. | 05-05-2011 |
Chuan-Yuan Li, Durham, NC US
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20100151576 | TARGETED TUMOR THERAPY BY USE OF RECOMBINANT ADENOVIRUS VECTORS THAT SELECTIVELY REPLICATE IN HYPOXIC REGIONS OF TUMORS - The presently claimed subject matter provides conditionally replication competent adenoviral vectors that confer selective cytotoxicity on cells expressing HIF-1 by infecting cells that allow HIF-1 inducible promoters present within the vectors to function. Also provided are compositions and host cells based upon the vectors, as well as methods of propagating and using the vectors. The presently claimed subject matter further provides a method of inhibiting tumor growth by co-infecting cells in a tumor with a conditionally replication competent adenovirus vector in conjunction with a replication deficient adenovirus vector. | 06-17-2010 |
Chuan-Yuan Li, Chapel Hill, NC US
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20110189262 | Methods and Compositions for Reducing Systemic Toxicity of Vectors - A method for reducing leakage of a delivery formulation from a target tissue via a damaged blood vessel during and after administration of the delivery formulation is provided. The method includes the steps of: (a) providing a delivery formulation comprising a blocking agent and one or more vectors encoding one or more polypeptides, wherein the delivery formulation is in a liquid form; and (b) administering the delivery formulation to a target tissue in a subject, wherein the administering results in the viscosity of the blocking agent increasing to at least about 100 cP, whereby leakage of the delivery formulation from the target tissue either during or after administration of the delivery formulation is reduced. | 08-04-2011 |
20150190456 | USE OF CASPASE 3 ACTIVITY AND ITS INHIBITORS - The present invention provides methods for using the level of caspase 3 activity for determining or prognosticating likelihood of cancer recurrence or relapse in a patient after the treatment for cancer. The present invention also provides methods for treating cancer in a patient using a caspase 3 inhibitor in conjunction with a conventional cancer treatment. | 07-09-2015 |
Fang Li, Durham, NC US
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20150190456 | USE OF CASPASE 3 ACTIVITY AND ITS INHIBITORS - The present invention provides methods for using the level of caspase 3 activity for determining or prognosticating likelihood of cancer recurrence or relapse in a patient after the treatment for cancer. The present invention also provides methods for treating cancer in a patient using a caspase 3 inhibitor in conjunction with a conventional cancer treatment. | 07-09-2015 |
Fanxing Li, Cary, NC US
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20140034134 | CIRCULATING FLUIDIZED BED WITH MOVING BED DOWNCOMERS AND GAS SEALING BETWEEN REACTORS - A system and process for carrying out one or more chemical reactions are provided and include one or more chemical reactors having particulate solids forming a bed therein, and a gas stripping zone forming a non-mechanical seal between said reactors which includes a conduit connecting the reactors. The conduit includes an inlet for a stripping gas which is adapted to prevent process gas from passing between reactors while permitting particulate solids to pass between reactors. | 02-06-2014 |
Feng-Qiao Li, Chapel Hill, NC US
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20100305024 | METHODS OF INHIBITING CALCINEURIN WITH APOE ANALOGS - The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelination and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described. | 12-02-2010 |
Guojie Li, Charlotte, NC US
Guorong Li, Chapel Hill, NC US
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20120142615 | METHODS RELATED TO THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY CONDITIONS - The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting NADPH oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide GGF; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan. | 06-07-2012 |
20140315785 | METHODS RELATED TO THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY CONDITIONS - The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting NADPH oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide GGF; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan. | 10-23-2014 |
Haibo Li, High Point, NC US
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20150259562 | Controlled Crosslinking of Latex Polymers With Polyfunctional Amines - The latex polymer compositions of the present invention exhibit latent crosslinking properties. Latent crosslinking in the polymers takes advantage of the fast interaction between the anionic latex charge and the cationic charge associated with polyfunctional amine crosslinkers. Once the latex is coated onto a substrate, the volatile base evaporates and the groups react to form a crosslinked coating with improved wash-off properties. | 09-17-2015 |
Hang Li, Charlotte, NC US
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20150174707 | PLURAL LAYER PUTTY-POWDER/SLURRY APPLICATION METHOD FOR SUPERALLOY COMPONENT CRACK VACUUM FURNACE HEALING - A process for repairing combined heavy erosion and thermal fatigue cracks and/or other defects, such as large cracks, in a high temperature superalloy component, such as a vane in a turbine section of a gas turbine engine, that does not require mechanical grinding to prepare the defect site. The process includes depositing a loose finely granulated superalloy powder or a low viscosity superalloy slurry in the crack up to a suitable level and then depositing a superalloy putty layer on the superalloy powder or slurry at the top of the crack A braze putty layer is then deposited over the superalloy putty layer and the component is sintered in a vacuum furnace to harden the superalloy putty and powder or slurry to repair the defect. | 06-25-2015 |
Hengguang Li, Morrisville, NC US
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20100113768 | PROCESS FOR PREPARING CEFSULODIN SODIUM - The invention is directed to an improved process for preparing cefsulodin sodium. The process involves: (i) dissolving cefsulodin in a solvent comprising an organic solvent to provide a solution of cefsulodin, (ii) adding about 1 equivalent of a sodium salt of a base to the solution of cefsulodin to provide a solution of cefsulodin sodium, and (iii) separating the cefsulodin sodium from the solution of cefsulodin sodium. | 05-06-2010 |
Hong Bin Li, Morrisville, NC US
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20110130647 | System And Method Using Coupler-Resonators For Electron Paramagnetic Resonance Spectroscopy - A coupler-resonator for electron paramagnetic resonance (EPR) spectroscopy in subjects has a wire loop formed into a coupling loop, a central transmission portion, and sensor loops. The sensor loops hold EPR sensor materials and are coated with biocompatible plastic. The coupler-resonator is implanted in a subject, the subject in a nonuniform magnetic field with a pickup coil for RF response measurement apparatus near the subject's skin and inductively coupled to the coupling loop. Resonances are measured at multiple sensor loops distinguished by sweeping magnetic field or radio frequency. A biopsy sampler has an outer needle with sensor loop and a central sampling needle with cavity for biopsy samples and EPR sensor material. A device for EPR of fingernails has sensor loops in a partial glove for holding loops next to fingertips. A device for EPR of teeth has sensor loops in plastic chips that can be held between the teeth. | 06-02-2011 |
Hsihua Li, Huntersville, NC US
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20110041528 | COOLER DISTRIBUTOR FOR A HEAT EXCHANGER - A distributor ( | 02-24-2011 |
20150096315 | Flash Tank Economizer for Two Stage Centrifugal Water Chillers | 04-09-2015 |
James Li, Mooresville, NC US
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20150198179 | COMPRESSOR SYSTEM WITH PRESSURE PULSATION DAMPENER AND CHECK VALVE - A system is disclosed wherein a pressure pulse dampener is in fluid communication with a compressed fluid. The pulse dampener being operable for reducing pressure pulsations within the fluid. In some embodiments a check valve can be in fluid communication with the pulse dampener to prevent reverse flow of the compressed fluid. | 07-16-2015 |
Jianquan Li, Cary, NC US
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20140187758 | Methods For Purifying Insect Membrane-Bound Receptor Proteins From Recombinant Production Hosts - The invention is drawn to a method for purifying membrane-bound proteins expressed in recombinant insect cells using N-laurosarcosine. The invention is particularly suited for expressing cadherin-type receptors cloned from | 07-03-2014 |
Jianye Li, Durham, NC US
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20100044697 | BRIGHT VISIBLE WAVELENGTH LUMINESCENT NANOSTRUCTURES AND METHODS OF MAKING AND DEVICES FOR USING THE SAME - Luminescent nanostructures (e.g., nanowires) and devices are provided which are capable of emitting bright visible light. The luminescent nanowires are most preferably in the form of a doped ZnO having a spectrally integrated ratio of visible to UV light of at least about 1000 or greater. The dopant for the ZnO luminescent nanowires may be at least one of sulfur, selenium, oxygen, zinc, magnesium, aluminum, with sulfur being especially preferred. The doped ZnO luminescent nanowires may be provided in devices for emitting visible light whereby visible light is emitted by the doped ZnO luminescent nanowires in response to excitation by UV light provided by a UV light source. The device may preferably comprise a transparent or translucent lens covering the UV light source, wherein the doped ZnO luminescent nanowires are present as a coating on a surface of the lens. In some embodiments, the device will comprise multiple UV light sources. Devices of the present invention may be provided with a flat panel lens which is positioned adjacent the multiple UV light sources and has a coating of the doped ZnO luminescent nanowires thereon. | 02-25-2010 |
Jingni Li, Charlotte, NC US
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20120290989 | Presentation of an Interactive User Interface - Examples of a user interface are described that may include a master risk landscape map that includes nodes representing risks and links representing correlations between the risks. The visual appearance of the nodes and links may provide information about their characteristics, such as risk likelihood, risks severity, risk detectability, and/or strength of interconnectivity. The user may be able to interact with the master risk landscape map to drill down to further detail while simultaneously removing less relevant information as desired, thereby potentially allowing the user to focus on the most relevant information. | 11-15-2012 |
Jun Hong Li, Wilson, NC US
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20090294151 | SKIN CURED PTFE WIRE AND CABLE - A wire having a conductor and an insulation where the insulation has a first inner layer of an uncured material and a second outer layer of a cured material. | 12-03-2009 |
Keqiang Li, Cary, NC US
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20090298751 | Arylalkyl and Heteroarylalkyl Derivaties of Cyclosporine a for the Treatment and Prevention of Viral Infection - This invention provides compounds of general formula (T): (I) wherein A, B, R | 12-03-2009 |
20090312300 | NOVEL MACROCYCLIC PEPTIDES - Disclosed are cyclosporine derivatives in which the 3-Sarcosine carbon and 5-Valine nitrogen are each substituted by a non-hydrogen substituent, and their use as pharmaceuticals, in particular for the treatment of hepatitis C virus. | 12-17-2009 |
20100173836 | NOVEL MACROCYCLES - Disclosed herein are compounds of general formula (I): | 07-08-2010 |
20110144005 | NOVEL CYCLIC PEPTIDES - Compounds are disclosed of general formula (I): | 06-16-2011 |
20140212381 | MACROCYCLES - Cyclosporin derivatives, methods of manufacturing the cyclosporin derivatives and methods for treating subjects infected with certain viruses, including hepatitis virus or HIV by administering the cyclosporin derivatives are described. | 07-31-2014 |
20140213508 | ANTIVIRAL MACROCYCLES - Cyclosporin derivatives, methods of manufacturing the cyclosporin derivatives and methods for treating subjects infected with certain viruses, including hepatitis virus or HIV by administering the cyclosporin derivatives are described. | 07-31-2014 |
Keqiang Li, Carey, NC US
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20090306033 | NOVEL CYCLIC PEPTIDES - Compounds are disclosed of general formula (I): | 12-10-2009 |
Li Li, Durham, NC US
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20150198713 | Method and System for Through-the-Wall Imaging using Compressive Sensing and MIMO Antenna Arrays - A method reconstructs a scene behind a wall by transmitting a signal through the wall into the scene. Parameters of the wall are estimated from a reflected signal. A model of a permittivity of the wall is generated using the parameters, and then the scene is reconstructed as an image from the reflected signal using the model and sparse recovery. | 07-16-2015 |
Lingbo Li, Durham, NC US
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20150134244 | Method for Predicting Travel Destinations Based on Historical Data - The embodiments of the invention provide a method in a navigation system, for predicting travel destinations according to a history of destinations. A model used for the prediction incorporates a database of destinations, which can include favorite, i.e., most probable, destinations for a user. The model also uses a context that can include features such as a current time of day, day of week, current location, current direction, past location, weather, and so on. The model infers the destination and destination categories even when the destination is not known precisely. Specifically, a method predicts destinations during travel, based on feature vectors representing current states of the travel, probabilities of destinations and categories of the destinations using a predictive model representing previous states of the travel. A subset of the destinations and categories of the destinations with highest probabilities are output for user selection. | 05-14-2015 |
Lingxiao Li, Cary, NC US
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20150228097 | Systems and Methods for Axis Table Plot Display - A graph display that includes a data plot and at least one data table is generated in response to a received graphing request to generate a graph display, wherein the graphing request specifies at least one pairing of an axis name and a table column name. The data plot of the generated graph display includes plot points located relative to a horizontal axis of the data plot identified by a horizontal axis name and located relative to a vertical axis of the data plot identified by a vertical axis name and textual representation of the data table aligned with the horizontal or vertical axis, and either the horizontal axis name or the vertical axis name corresponds to the axis name of the at least one pairing in the graphing request. | 08-13-2015 |
Scott Wantao Li, Cary, NC US
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20150227319 | NON-VOLATILE STORAGE DEVICE IMAGE CREATION - An embodiment provides a method, including: integrating a non-volatile memory into a first information handling device; installing an image on the non-volatile memory; storing a recovery version of the installed image in another memory location of another device; and thereafter providing the recovery version to a non-volatile memory of a second information handling device. Other aspects are described and claimed. | 08-13-2015 |
Scott Wentao Li, Cary, NC US
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20150256017 | ENERGY TRANSFER MECHANISM - A device and method of transferring energy between peer devices includes determining an amount of energy to transfer from a provider battery powered peer device to a consumer battery powered peer device, selecting an energy transfer connection between the provider device and the consumer device, and initiating transfer of energy via the energy transfer connection. | 09-10-2015 |
Shi Man Li, Mooresville, NC US
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20150064946 | RADIO FREQUENCY SUBSCRIBER DROP EQUIPMENT HAVING HIGH VOLTAGE PROTECTION CIRCUITS AND RELATED CONTACT ASSEMBLIES - RF subscriber drop units have a housing that has a port aperture therethrough and a connector port that extends outwardly from the housing and surrounds the port aperture. The connector port includes a contact assembly that holds a spring contact, the spring contact including a contact tail that extends through the port aperture. A conductive spark gap unit that has a spark gap aperture is further provided and arranged so that the contact tail extends through the spark gap aperture. | 03-05-2015 |
20150113586 | RADIO FREQUENCY AND FIBER OPTIC SUBSCRIBER DROP EQUIPMENT HAVING IMPACT RESISTANT HOUSINGS AND RELATED HOUSINGS AND METHODS - Subscriber drop units include a housing having a top wall that has an exterior surface and an interior surface and a plurality of sidewalls that extend downwardly from the top wall, the top wall and the sidewalls defining an interior cavity. An input port and at least one output port extend through the housing. A printed circuit board is mounted within the interior cavity. The exterior surface of the top wall includes a first ridge that extends upwardly above a first of the sidewalls and a second ridge that extends upwardly above a second of the sidewalls | 04-23-2015 |
20150130555 | RADIO FREQUENCY SUBSCRIBER DROP UNITS HAVING PRINTED CIRCUIT BOARDS WITH GROUND PLANE LAYERS AND/OR HOUSINGS WITH GROUND WALLS - Radio frequency subscriber drop units include a housing having an input port and an output port and a printed circuit board mounted in an interior of the housing. The printed circuit board includes a dielectric layer, a wiring layer that includes conductive wirings that comprise at least part of a communications path between the input port and the output port that is on a first face of the dielectric layer, and a ground plane layer that includes a conductive ground plane that is on a second face of the dielectric layer. | 05-14-2015 |
20150207525 | SIGNAL AMPLIFIERS THAT SUPPORT MOCA COMMUNICATIONS AT BOTH ACTIVE AND PASSIVE OUTPUT PORTS - RF signal amplifiers are provided that include an RF input port, a power divider network having a plurality of active output ports, an active path connecting the RF input port to the power divider network, the active path including an upstream diplexer, a downstream diplexer and a power amplifier between the upstream diplexer and the downstream diplexer, a passive output port, a MoCA diplexer that is coupled to the passive output port, a passive path connecting the RF input port to the MoCA diplexer and a MoCA rejection filter between the power divider network and the active path. | 07-23-2015 |
Shi Man Li, Hickory, NC US
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20130090010 | Surge Protector Components Having a Plurality of Spark Gap Members Between a Central Conductor and an Outer Housing - A coaxial connector includes a surge protection component including a plurality of elongated members, a body portion that is configured to receive the surge protection component such that the elongated members extend along an outer surface thereof, and a center conductor disposed inside the body portion and spaced apart from the surge protection component so as to create a gap therebetween | 04-11-2013 |
20130343245 | SIGNAL AMPLIFIERS THAT SWITCH TO AN ATTENUATED OR ALTERNATE COMMUNICATIONS PATH IN RESPONSE TO A POWER INTERRUPTION - RF signal amplifiers are provided that include an RF input port, a switching device having an input that is coupled to the RF input port, a first output and a second output, a first diplexer having an input that is coupled to both the first output of the switching device and the second output of the switching device, and a first RF output port that is coupled to an output of the first diplexer. These amplifiers further include an attenuator that is coupled between the second output of the switching device and the input of the first diplexer. | 12-26-2013 |
20150138960 | SIGNAL AMPLIFIERS THAT SWITCH TO AN ATTENUATED OR ALTERNATE COMMUNICATIONS PATH IN RESPONSE TO A POWER INTERRUPTION - RF signal amplifiers are provided that include an RF input port, a switching device having an input that is coupled to the RF input port, a first output and a second output, a first diplexer having an input that is coupled to both the first output of the switching device and the second output of the switching device, and a first RF output port that is coupled to an output of the first diplexer. These amplifiers further include an attenuator that is coupled between the second output of the switching device and the input of the first diplexer. | 05-21-2015 |
Shyh-Dar Li, Carrboro, NC US
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20110117026 | METHODS AND COMPOSITIONS FOR THE DELIVERY OF BIOACTIVE COMPOUNDS - The present invention provides compositions comprising delivery systems comprising a lipid vehicle, a bioactive compound, and a polyanionic carrier macromolecule that is not a carrier polynucleotide, wherein the lipid vehicle encapsulates the polynucleotide of interest and the polyanionic carrier macromolecule, and wherein the delivery system is essentially free of carrier polynucleotides. Compositions also include delivery systems comprising a lipid vehicle and a bioactive agent, wherein the lipid vehicle encapsulates the bioactive agent, and wherein the lipid vehicle comprises a covalent bilayer or a core supported bilayer comprising polycationic lipids. Other compositions provided herein comprise a delivery system comprising a polypeptide of interest and a means for delivering the polypeptide into a cell. Also provided herein are methods for making the delivery systems, methods for delivering bioactive compounds, methods for treating a disease or unwanted condition in a subject with the delivery systems, and methods for detecting apoptosis in a cell. | 05-19-2011 |
20110117141 | METHODS AND COMPOSITIONS COMPRISING NOVEL CATIONIC LIPIDS - Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can be used alone or in combination with a cytotoxic bioactive compound to kill a cell. In some of these claims, the cationic lipid enhances the cytotoxic activity of the cytotoxic bioactive compound. Methods for treating a subject afflicted with a disease or unwanted condition are provided, wherein the method comprises administering a delivery system comprising a novel cationic lipid to the subject. The invention further provides methods for making delivery systems comprising the novel cationic lipids of the invention. | 05-19-2011 |
Tong Li, Cary, NC US
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20120331125 | Resource Use Management System - A method and apparatus for managing resources is provided. Responsive to a request for a set of resources by a user, a token is added to a response to the request generated by a server application. The requests are monitored from the user. The token identifies the user. A pattern of use by the user is identified. A determination is made as to whether overuse of the set of resources has occurred based on the pattern of use and a policy. | 12-27-2012 |
Wei Li, Durham, NC US
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20120321162 | SYSTEMS AND METHODS FOR IMAGING AND QUANTIFYING TISSUE MAGNETISM WITH MAGNETIC RESONANCE IMAGING - Systems and methods for imaging and quantifying tissue magnetism with magnetic resonance imaging (MRI) are disclosed. According to an aspect, a method for MRI includes using an MRI system to acquire multiple image echoes of an object. The method also includes combining the image echoes. Further, the method includes generating an image of the object based on the combined image echoes for depicting a characteristic of the object. | 12-20-2012 |
Wenping Li, Cary, NC US
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20110004355 | Hybrid Distribution Network Power Restoration Control - A power outage restoration system manages a power network including a plurality of switching devices. The power outage restoration system includes an outage management system having a network model of said power network. A plurality of local restoration controllers are in communication with the outage management system and each said local restoration controller includes a trimmed network model correlating to a respective area of responsibility. | 01-06-2011 |
Xianggan Li, Durham, NC US
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20140366223 | METHODS FOR GENERATING TRANSGENIC PLANTS - This invention provides a method for generating transgenic plants with a low copy number. Plant cells are transformed with polynucleotides containing transcriptional cassettes designed to trigger silencing of a gene which is essential for the plant cell to survive the transformation and regeneration process. The present invention enables the recovery of an increased number of transgenic plants which have only one copy of each desired transcriptional cassette. | 12-11-2014 |
Xiaoling Li, Chapel Hill, NC US
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20100240029 | Cholesterol-Regulating Complex of SIRT1 and LXR and Methods of Use - A cholesterol-regulating complex of SIRT1 and LXR and methods of use are disclosed. SIRT1 forms a complex with LXR bound to an LXR element. Methods of forming the complex, identifying an agent that modulates formation of the complex, increasing the ratio of cholesterol bound to high density lipoprotein (HDL) to total cholesterol in the plasma of a mammal, promoting ABCA1-mediated cholesterol efflux from a mammalian cell, treating a subject deemed to have a level of SIRT1 activity that is below normal, assessing whether a candidate substance modulates an LXR-dependent process, and assessing whether a candidate substance modulates an SIRT1-dependent effect of an LXR are disclosed. | 09-23-2010 |
Xingxiang Li, Cary, NC US
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20130302219 | DEVICE FOR COLLECTING ORAL FLUID SAMPLES AND THE LIKE - Devices for collection and elution of oral fluid samples and the like enable collection and elution of samples by using a handle in the form of a rod having a collection pad thereon which is inserted into a collection tube. The collection tube has an adaptor with a narrowed portion associated therewith for squeezing the pad to wring a sample therefrom. In an alternative embodiment, the collection tube has a narrowed portion that squeezes the pad as the pad is inserted there though. Caps are provided to 1) support the rod in an assembly with the adaptor and collection tube to form an assembled sample collection device and 2) to close the collection tube after the handle and pad are removed from the collection tube subsequent to depositing the sample elution solution therein. The eluted sample can be used for detection of an analyte. | 11-14-2013 |
Xuefa Li, Matthews, NC US
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20110176661 | X-RAY SENSITIVE BATTERY SEPARATORS AND RELATED METHODS - The instant application relates to an X-ray sensitive battery separator for a secondary lithium battery and a method for detecting the position of a separator in a secondary lithium battery. The X-ray sensitive battery separator includes a microporous membrane having an X-ray detectable element therein, thereon, or added thereto. The X-ray detectable element constitutes less than 20% by weight of the microporous membrane or separator. The method for detecting the position of a separator in a battery, cell, stack, jellyroll, can, or the like includes the following steps: (1) providing a battery, cell, stack, jellyroll, or the like including an X-ray sensitive battery separator; (2) subjecting the battery, cell, stack, jellyroll, or the like to X-ray radiation; and (3) thereby detecting the position of said separator in said battery, cell, stack, jellyroll, or the like. | 07-21-2011 |
20140045033 | SEPARATOR MEMBRANES FOR LITHIUM ION BATTERIES AND RELATED METHODS - A battery separator for a secondary lithium battery includes a microporous/porous membrane with a ceramic coating of one or more layers, a layer may include one or more particles and/or binders. | 02-13-2014 |
Xuening Li, Cary, NC US
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20090284322 | SYNCHRONOUSLY STACKABLE DOUBLE-EDGE MODULATED PULSE WIDTH MODULATION GENERATORS - Synchronously stackable double-edge modulated pulse width modulation generators are disclosed. An example pulse width modulation generator includes a ramp generator to generate first and second ramp signals that interact to form a virtual ramp signal; and a comparator module coupled to the ramp generator configured to produce a pulse width modulated signal based on a comparison between the virtual ramp signal and an input signal. | 11-19-2009 |
20100148737 | DISCONTINUOUS CONDUCTION MODE PULSE-WIDTH MODULATION - One embodiment of the invention includes a power regulator system. The system includes a switching system configured to generate an output voltage across a load based on a high-side switch coupling a power voltage to an output at an edge-trigger of a PWM control signal having an activation pulse-width of the high-side switch. The system also includes a switch driver system configured to set a duty-cycle of the PWM control signal such that the activation pulse-width of the PWM control signal is based on the power regulator system operating in one of a continuous conduction mode (CCM) and a discontinuous conduction mode (DCM). The edge-trigger of the PWM control signal can occur based on a relative magnitude of the output voltage and the power voltage while operating in the DCM. | 06-17-2010 |
20120032748 | Systems and Methods of Ripple Reduction in a DC/DC Converter - Systems and devices for ripple reduction in a DC/DC converter are presented. The disclosed systems and methods enable ripple reduction in discontinuous conduction mode (DCM) operation. In DCM, the inductor current peak to peak ripple may be reduced based on the load current. To achieve the reduction of the inductor peak to peak current ripple, a digital counter is used to count the time between consecutive PWM pulses. The digital output of the counter is used to control the pulse width modulation. As the digital output of the counter increases, the PWM on-time decreases. Since the PWM pulse is demanded by the load in DCM mode, the peak to peak inductor ripple is modulated by the counter, or, in turn, modulated by the load current. | 02-09-2012 |
20120038331 | Systems and Methods of Smooth Light Load Operation in a DC/DC Converter - Systems and devices for smooth light load operation in a DC/DC converter are presented. The disclosed systems and methods enable smooth discontinuous conduction mode (DCM)/continuous conduction mode (CCM) transition. The disclosed systems and methods of smooth light load operation in a DC/DC converter may also avoid the generation of sub-harmonics during light load operation. In an example embodiment, a rising ramp is used to control the ON time of the converter oscillator, while a falling ramp controls the OFF time. During DCM operation, the minimum value of the falling ramp is clamped. The clamping of the falling ramp ensures a substantially similar level of the error amplifier output in both CCM and DCM and avoids disturbances caused by a difference in the error amplifier outputs between the modes. | 02-16-2012 |
Xuewen Li, Cary, NC US
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20110228766 | LOOP CONDITION PREVENTION AT INTERNETWORK INTERFACE BOUNDARY - The present invention provides a solution to maximize the chance of completion for an ISUP to SIP direction call by enabling a bigger factor for converting ISUP hop counter to SIP Max-Forwards value than the reverse direction thus enabling more hops in the SIP network. Enabling a bigger factor for ISUP to SIP direction can cause loops without special considerations. This invention provides an algorithm that prevents a “loop condition” that can arise at the interface boundary of two telephone networks, known by their standard names ISUP and SIP networks. The present invention solves the “loop condition” problem by adjusting the Hop Counter and Max-Forward parameter values in a predetermined manner such that the adjusted parameter values break the cycle of providing the same parameter values between networks at the network boundary for an uncompleted connection, or break an endless “loop condition”. | 09-22-2011 |
20140160993 | LOOP CONDITION PREVENTION AT INTERNETWORK INTERFACE BOUNDARY - The present invention provides a solution to maximize the chance of completion for an ISUP to SIP direction call by enabling a bigger factor for converting ISUP hop counter to SIP Max-Forwards value than the reverse direction thus enabling more hops in the SIP network. Enabling a bigger factor for ISUP to SIP direction can cause loops without special considerations. This invention provides an algorithm that prevents a “loop condition” that can arise at the interface boundary of two telephone networks, known by their standard names 1SUP and SIP networks. The present invention solves the “loop condition” problem by adjusting the Hop Counter and Max-Forward parameter values in a predetermined manner such that the adjusted parameter values break the cycle of providing the same parameter values between networks at the network boundary for an uncompleted connection, or break an endless “loop condition”. | 06-12-2014 |
Yangxing Li, Belmont, NC US
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20080283155 | Stabilized lithium metal powder for Li-ion application, composition and process - The present invention provides a method for stabilizing lithium metal powder. The method comprises the steps of heating the lithium metal powder to above its melting point to provide molten lithium metal, dispersing the molten lithium metal, and contacting the dispersed molten lithium metal with a phosphorous-containing compound to provide a substantially continuous protective layer of lithium phosphate on the lithium metal powder. | 11-20-2008 |
20090035663 | STABILIZED LITHIUM METAL POWDER FOR LI-ION APPLICATION, COMPOSITION AND PROCESS - The present invention provides a lithium metal powder protected by a wax. The resulting lithium metal powder has improved stability and improved storage life. | 02-05-2009 |
20090061321 | STABILIZED LITHIUM METAL POWDER FOR LI-ION APPLICATION, COMPOSITION AND PROCESS - The present invention provides a lithium metal powder protected by a substantially continuous layer of a polymer. Such a substantially continuous polymer layer provides improved protection such as compared to typical CO | 03-05-2009 |
20110135810 | FINELY DEPOSITED LITHIUM METAL POWDER - The present invention provides a method of finely depositing lithium metal powder or thin lithium foil onto a substrate while avoiding the use of a solvent. The method includes depositing lithium metal powder or thin lithium foil onto a carrier, contacting the carrier with a substrate having a higher affinity for the lithium metal powder as compared to the affinity of the carrier for the lithium metal powder, subjecting the substrate while in contact with the carrier to conditions sufficient to transfer the lithium metal powder or lithium foil deposited on the carrier to the substrate, and separating the carrier and substrate so as to maintain the lithium metal powder or lithium metal foil, deposited on the substrate. | 06-09-2011 |
20110226987 | ANODE FOR ELECTROCHEMICAL SYSTEM - The present invention provides an anode including a host material capable of absorbing or desorbing lithium in an electrochemical system. A stabilized lithium metal powder coated with a wax is dispersed in the host material. | 09-22-2011 |
20110300385 | STABILIZED LITHIUM METAL POWDER FOR LI-ION APPLICATION, COMPOSITION AND PROCESS - The present invention provides a stabilized lithium metal powder having a substantially continuous protective layer of lithium phosphate on the lithium metal powder. | 12-08-2011 |
20150132641 | STABILIZED LITHIUM METAL POWDER FOR LI-ION APPLICATION, COMPOSITION AND PROCESS - The present invention provides a lithium metal powder protected by a wax. The resulting lithium metal powder has improved stability and improved storage life. | 05-14-2015 |
Yanpeng Li, Raleigh, NC US
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20140353166 | NOVEL PROCESS FOR SCALABLE SYNTHESIS OF MOLYBDENUM DISULFIDE MONOLAYER AND FEW-LAYER FILMS - The present disclosure relates to nanosheet synthesis. More particularly, the present disclosure relates to molybdenum sulfide (MoS | 12-04-2014 |
Yi-Ju Li, Durham, NC US
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20090098557 | IDENTIFICATION OF GENETIC MARKERS ASSOCIATED WITH PARKINSON DISEASE - The present invention provides methods and compositions for screening a subject for Parkinson disease, for increased risk of developing Parkinson disease and/or for an earlier or later age of developing Parkinson disease, comprising detecting the presence of a genetic marker associated with Parkinson disease. | 04-16-2009 |
Yin-Xiong Li, Durham, NC US
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20080233626 | Enhanced broad-spectrum UV radiation filters and methods - The present invention obtains from the discovery that combining traditional UV pigments, organic chemicals, or both, combined with NA, creates a broad spectrum UV absorbing additive that is much more efficient than using any of the ingredients by themselves. Methods for producing NA-coated particles as a UV protection additive to paints, fiberglass, plastic, polymers, siloxanes/silicates/reactive silanols, sealants or other film forming coatings or penetrating fluids and solid articles are contemplated in this invention as well as the coatings, sealants and other protectants and the coated and/or finished articles themselves. | 09-25-2008 |
20090137544 | Formation and rejuvenation of organs and alcohol damaged organ regeneration through stem cell nutrients - Mechanisms nourish stem cells for organ regeneration and prevent alcohol related diseases such as Fetal Alcohol Syndrome (FAS) and Liver Sclerosis. These stem cell nutrients have been found to positively affect the skin, liver, brain neurons, pancreas, and the GI tract. Cholesterol supplementation prevents fetal alcohol spectrum defects (FASD) in alcohol-exposed zebra fish embryos. Using the zebra fish model, alcohol was found to interfere with embryonic development by disrupting cholesterol-dependent activation of a critical signaling molecule, sonic hedgehog (Shh). Cholesterol supplementation of the alcohol-exposed embryos restored the functionality of the molecular pathway and prevented development of FASD-like defects. Novel biomarkers were identified for diagnosing alcohol related diseases by lipid chemical analysis and Raman Spectroscope. | 05-28-2009 |
20130251693 | COMPOSITION AND METHOD FOR IN VIVO AND IN VITRO ATTENUATION OF GENE EXPRESSION USING DOUBLE STRANDED RNA - Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression. | 09-26-2013 |
20150152413 | Composition and Method for In Vivo and In Vitro Attenuation of Gene Expression Using Double Stranded RNA - Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression. | 06-04-2015 |
Yongchen Li, Cary, NC US
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20120166929 | SYSTEM AND METHOD FOR PROVIDING A CONTEXT-SENSITIVE USER INTERFACE - Exemplary embodiments disclose a method and system for providing a context-sensitive user interface. The method and system include dynamically creating an ontology by storing data values entered by different users from the same or different computers into fields of at least one form, where the data values stored in the ontology includes both verified data that has been verified by at least one workflow, and unverified data that has not been verified by the at least one workflow; in response to a current user interacting with a current form, retrieving from the ontology the data values made by the different users and presenting the retrieved data values to the current user as autocomplete suggestions, where the autocomplete suggestions includes the verified data and the unverified data; dynamically adjusting the autocomplete suggestions for the current user of the current form as new data values of other users are received and stored in the ontology; and distinguishing the unverified data from the verified data using at least one of a visual representation and an audio representation of the quality of the autocomplete suggestions. | 06-28-2012 |
Yongcheng Li, Research Triangle Park, NC US
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20110145333 | Method and Apparatus for Enhancing Compound Documents with Questions and Answers - A server system runs a bot service that registers an FAQ (frequently asked questions) for a document having an embedded object. The FAQ includes one or more question-and-answer (Q&A) pairs. The bot service receives, from each electronics device that renders a copy of the document, a request from the embedded object for the FAQ registered for the document, and transmits the FAQ to each electronic device from which a request is received. Each electronics device displays the FAQ, including the one or more Q&A pairs, within its rendered copy of the document. Any viewer of a copy of the document with the embedded object can submit a question to the bot service through the embedded object. The bot service uses a messaging service to obtain an answer to the question from an author. The FAQs displayed at the electronics devices are updated to include the new Q&A pair. | 06-16-2011 |
20120226762 | METHOD AND APPARATUS FOR ENHANCING COMPOUND DOCUMENTS WITH QUESTIONS AND ANSWERS - A server system runs a bot service that registers an FAQ (frequently asked questions) for a document having an embedded object. The FAQ includes one or more question-and-answer (Q&A) pairs. The bot service receives, from each electronics device that renders a copy of the document, a request from the embedded object for the FAQ registered for the document, and transmits the FAQ to each electronic device from which a request is received. Each electronics device displays the FAQ, including the one or more Q&A pairs, within its rendered copy of the document. Any viewer of a copy of the document with the embedded object can submit a question to the bot service through the embedded object. The bot service uses a messaging service to obtain an answer to the question from an author. The FAQs displayed at the electronics devices are updated to include the new Q&A pair. | 09-06-2012 |
Yongcheng Li, Raleigh, NC US
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20150256489 | ADAPTIVE GUIDANCE FOR MANAGING A COMMUNICATIONS REPOSITORY - A tool for analyzing accessible data to provide recommendations to a user for how to manage communications. The tool receives a request to provide a recommendation for how to manage a specific communication. The tool requests accessible data for the specific communication. The tool determines a recommendation for how to manage the specific communication. The tool presents the recommendation for how to manage the specific communication. | 09-10-2015 |
Yuling Li, Chapel Hill, NC US
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20090028817 | Compositions and methods for soft tissue augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-29-2009 |
20090319033 | METHOD FOR ENDOTHELIAL CELL EXTRACTION FROM ADISPOSE TISSUES - Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts. | 12-24-2009 |
20110020271 | ELASTIN FOR SOFT TISSUE AUGMENTATION - The present invention provides compositions comprising isolated elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 01-27-2011 |
20120230950 | Compositions and Methods for Soft Tissue Augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 09-13-2012 |
20140356323 | Compositions and Methods for Soft Tissue Augmentation - The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation. | 12-04-2014 |
20140358220 | Method for Endothelial Cell Extraction from Adipose Tissues - Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts. | 12-04-2014 |
Zhao Li, Raleigh, NC US
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20130085624 | Systems and Methods for Integrating Demand Response with Service Restoration in an Electric Distribution System - Systems and methods for integrating demand response with service restoration in an electric distribution system. The electric distribution system may include a plurality of regions, zones, and/or areas including at least an outage area that includes a fault and is not receiving electric current from the electric distribution system and a restoration area that is receiving electric current from the electric distribution system and that may be selectively configured to provide electric current to a selected portion of the outage area. The electric distribution system also includes a plurality of demand responsive loads configured to be selectively isolated from the electric distribution system responsive to a load shed signal. The demand responsive loads may be selectively utilized during service restoration, such as to provide additional excess capacity within the restoration area and/or decrease a magnitude of the electric load applied by the selected portion of the outage area. | 04-04-2013 |
20140108851 | Online Protection Coordination for Distribution Management System - A method for automatic protection coordination in a power system network comprises identifying radial source-to-load paths and fault protection devices in the source-to-load paths, for a portion of the power system network to be coordinated. Device settings data for fault protection devices are retrieved, including multiple preconfigured settings for some devices. Fault currents for each of multiple possible electrical faults in said portion of the power system network are predicted, and a selectivity check for each pair of fault protection devices that are adjacent to one another in an identified radial source-to-load path is performed, for each of one or more of the predicted fault currents, taking into account multiple preconfigured settings for remotely controllable fault protection devices. A combination of settings for remotely controllable fault protection devices that minimizes selectivity violations among the pairs is selected, and necessary change-setting commands are sent to remotely controllable fault protection devices. | 04-17-2014 |
20150039145 | Microgrid Energy Management System and Method for Controlling Operation of a Microgrid - A microgrid includes a plurality of distributed energy resources such as controllable distributed electric generators and electrical energy storage devices. A method of controlling operation of the microgrid includes periodically updating a distributed energy resource schedule for the microgrid that includes on/off status of the controllable distributed electric generators and charging/discharging status and rate of the electrical energy storage devices and which satisfies a first control objective for a defined time window, based at least in part on a renewable energy generation and load forecast for the microgrid. The method further includes periodically determining power set points for the controllable distributed energy resources which satisfy a second control objective for a present time interval within the defined time window, the second control objective being a function of at least the distributed energy resource schedule for the microgrid. | 02-05-2015 |
Zhuowei Li, Chapel Hill, NC US
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20120142650 | METHOD FOR TREATING LUNG DISEASE - Methods of treating lung diseases comprising administering inducers of NAD(P)H:quinone oxidoreductase 1 (NQO1) are disclosed. Inducers of NQO1 include naphthoquinones such as β-lapachone. Methods of predicting whether a subject with a lung disease will respond to treatment with a naphthoquinone are also described herein. | 06-07-2012 |
20140155361 | METHOD FOR TREATING LUNG DISEASE - Methods of treating lung diseases comprising administering inducers of NAD(P)H:quinone oxidoreductase 1 (NQO1) are disclosed. Inducers of NQO1 include naphthoquinones such as β-lapachone. Methods of predicting whether a subject with a lung disease will respond to treatment with a naphthoquinone are also described herein. | 06-05-2014 |