Li, DE
Balin Li, Hockessin, DE US
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20110277183 | ALTERATION OF PLANT ARCHITECTURE CHARACTERISTICS IN PLANTS - This invention provides isolated polynucleotides, polypeptides, and recombinant DNA constructs useful for conferring an alteration in one or more plant architecture characteristics. Also provided are methods utilizing these polynucleotides, polypeptides, and recombinant DNA constructs. In certain embodiments, the recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a Squatty-Crinkle-Leaf Polypeptide. | 11-10-2011 |
20140234840 | MOLECULAR MARKERS LINKED TO PPO INHIBITOR TOLERANCE IN SOYBEANS - This invention relates generally to the detection of genetic differences among soybeans. More particularly, the invention relates to soybean quantitative trait loci (QTL) for tolerance to protoporphyrinogen oxidase inhibitors, to soybean plants possessing these QTLs, which map to a novel chromosomal region, and to genetic markers that are indicative of phenotypes associated with protoporphyrinogen oxidase inhibitor tolerance. Methods and compositions for use of these markers in genotyping of soybean and selection are also disclosed. | 08-21-2014 |
Chunhong Li, Bear, DE US
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20080207625 | Synthesis and Purification of Pteroic Acid and Conjugates Thereof - Methods for purifying pteroic acid, analogs of pteroic acid, and derivatives of pteroic acid are described. Methods for synthesizing and purifying conjugates of vitamins, including FITC conjugates of folic acid, folic acid analogs, and derivatives of folic acid and folic acid analogs are also described. Purified forms of pteroic acid, derivatives and analogs of pteroic acid, and conjugates thereof are also described. | 08-28-2008 |
Eric Chuanzhao Li, Wilmington, DE US
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20110159577 | DIVIDER FOR USE WITH BIOLISTIC BOMBARDMENT DEVICE - The present invention is designed for use with a biolistic bombardment device having a cold gas shock wave splitter that divides a cold gas shock wave into two or more separate pressure waves that burst into one or more macrocarrier disks so as to create two or more separate microparticle groups. In various embodiments, the present invention provides a divider that is configured to define two or more separate bombardment areas, each configured to contain a respective target and to receive a separate one of the microparticle groups created by a cold gas shock wave splitter. In such a manner, the present invention avoids mixing of microparticles between microparticle groups and allows for independent biolistic bombardment of the targets. | 06-30-2011 |
20140099702 | DIVIDER FOR USE WITH BIOLISTIC BOMBARDMENT DEVICE - The present invention is designed for use with a biolistic bombardment device having a cold gas shock wave splitter that divides a cold gas shock wave into two or more separate pressure waves that burst into one or more macrocarrier disks so as to create two or more separate microparticle groups. In various embodiments, the present invention provides a divider that is configured to define two or more separate bombardment areas, each configured to contain a respective target and to receive a separate one of the microparticle groups created by a cold gas shock wave splitter. In such a manner, the present invention avoids mixing of microparticles between microparticle groups and allows for independent biolistic bombardment of the targets. | 04-10-2014 |
Huidong Li, Newark, DE US
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20100051447 | SOL-GEL PRECURSORS AND METHODS FOR MAKING LEAD-BASED PEROVSKITE FILMS - A simple, economical sol-gel method was invented to produce thick and dense lead zirconate titanate (PZT) thin films that exhibit the stoichiometric chemical composition and unprecedented electrical and dielectric properties. The PZT films are the foundation of many microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS) for micro/nano sensors and actuators applications. | 03-04-2010 |
Hui-Yin Li, Hockessin, DE US
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20080248105 | POLYMORPHIC FORMS OF 6-11 BICYCLIC KETOLIDE DERIVATIVES - The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing the various polymorphic forms in pure form or in combination with one another. The present invention also provides pharmaceutical compositions and formulations comprising the polymorphic and amorphous forms and methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment. | 10-09-2008 |
20080312259 | SALTS OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-d]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYLPROPANENITRILE - The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. | 12-18-2008 |
20090099206 | SOLID FORMS OF (S)-2-AMINO-3-(4-(2-AMINO-6-((R)-2,2,2-TRIFLUORO-1-(3'-METHOXYBIPHENYL-4-- YL)ETHOXY)PYRIMIDIN-4-YL)PHENYL)PROPANOIC ACID AND METHODS OF THEIR USE - Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-2,2,2-trifluoro-1-(3′-methoxybiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid and salts thereof are disclosed. | 04-16-2009 |
20110052701 | PARTICULATES OF A CRTH2 ANTAGONIST - Provided herein are particulates of {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl} acetic acid in amorphous or crystalline forms, processes for their preparation, pharmaceutical compositions comprising them, and methods of their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease. | 03-03-2011 |
20110224190 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS - The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 09-15-2011 |
20120214809 | Aminoindane Compounds and Use Thereof in Treating Pain - The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPV 1 receptor activator. In one embodiment, the TRPV 1 receptor activator is lidocaine. | 08-23-2012 |
20140094476 | SALTS OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYL- PROPANENITRILE - The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. | 04-03-2014 |
20140094477 | SALTS OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYL- PROPANENITRILE - The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. | 04-03-2014 |
20140100254 | Radezolid salts and polymorphic forms thereof - Disclosed are compounds of Formula 1a, | 04-10-2014 |
20140235635 | SYNTHESIS AND USE OF KINASE INHIBITORS - An improved synthesis of a class of inhibitor of Focal Adhesion Kinase (FAK) is provided, wherein use of an expensive palladium-based catalyst is reduced and reaction yields and product purities are improved. Two key reactions of coupling of aryl halides with anilines are optimized with the surprising discovery that the palladium-based catalyst can be dispensed with entirely in one of the reactions. The invention also provides the use of the FAK-inhibitory compounds in the treatment of inflammatory and immune disorders and of arthritis. | 08-21-2014 |
20140275031 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS - The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases. | 09-18-2014 |
20140303196 | SALTS OF THE JANUS KINASE INHIBITOR (R)-3-(4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL)-3-CYCLOPENTYL- PROPANENITRILE - The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. | 10-09-2014 |
Ke Li, Wilmington, DE US
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20110201832 | VAPOR-PHASE DECARBONYLATION PROCESS - A process is provided for the synthesis of furan and related compounds by vapor phase decarbonylation of furfural and derivatives, using a palladium/alumina catalyst that has been promoted with an alkali carbonate. Catalyst lifetime is improved. The catalyst can be regenerated in situ by feeding a mixture of air and steam, with a composition of between about 2% and about 40% air, to the catalyst bed at a temperature between about 300° C. and about 500° C. | 08-18-2011 |
20120157698 | DECARBONYLATION PROCESS - A process is provided for the synthesis of furan and related compounds by liquid-phase decarbonylation of furfural and derivatives, using a palladium/metal aluminate catalyst. The compounds so produced can be used as starting materials for industrial chemicals for use as pharmaceuticals, herbicides, stabilizers, and polymers such as polyether ester elastomers and polyurethane elastomers. | 06-21-2012 |
20120165561 | VAPOR-PHASE DECARBONYLATION PROCESS - A process is provided for the synthesis of furan and related compounds by vapor-phase decarbonylation of furfural and derivatives, using a palladium/metal aluminate catalyst that has been promoted with an alkali carbonate, such as cesium carbonate. The use of such catalysts, which are inherently less acidic than alumina, results in improved lifetime and high productivity. | 06-28-2012 |
Qingxiong Li, Newark, DE US
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20110081110 | Fiber Spectroscopic Probe Mountable On a Microscope - A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope. | 04-07-2011 |
20110081111 | Fiber Spectroscopic Probe Mountable On a Microscope - A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The constructed microscope with fiber spectroscopic probe is suitable for micro-sampling, Raman analysis, as well as fluorescence analysis and can be easily reconfigured for different excitation/detection wavelengths. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope. | 04-07-2011 |
Sunny Xiang Li, Newark, DE US
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20140093931 | PRODUCTION OF FERMENTATION PRODUCTS - The invention relates to processes for the production of fermentation products such as alcohols including ethanol and butanol, and the development of microorganisms capable of producing fermentation products via an engineered pathway in the microorganisms. | 04-03-2014 |
Tong Li, Newark, DE US
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20120078408 | Advanced Control System For Steam Hydrocarbon Reforming Furnaces - Embodiments of the invention provide an advanced control system for steam hydrocarbon reformer furnaces, especially steam methane reformer furnaces. As described herein, the advanced control system may improve the control quality and efficiency of adjusting steam hydrocarbon reformer furnaces operating coefficients. As a result, the steam hydrocarbon reformer furnace operations become more stable, resulting in energy savings and improved furnace yield. | 03-29-2012 |
Wenzhe Li, Middletown, DE US
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20150212055 | Sensitive Method for Measuring Cis-Diol Containing Compounds in Plasma Using 2D-LC-MS/MS - The present invention provides methods for determining the amount of cis-diol containing compounds in a biological samples using mass spectrometry, particularly catecholamines (dopamine, epinephrine, norepinephrine) in a plasma sample. After a sample is mixed with an internal standard, extracted with a two-step liquid-liquid extraction process utilizing phenylboronic acid chemistry, and then derivatized with a benzoyl chloride-like agent, relevant moieties are then separated chromatographically and detected by MS/MS whereby specific ion transitions are monitored. This invention has several clinical utilities, particularly those related to measuring plasma catecholamines in patients. | 07-30-2015 |
Xiao-Yi Li, Wilmington, DE US
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20140223595 | DROUGHT TOLERANT PLANTS AND RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING DTP6 POLYPEPTIDES - Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP6 polypeptide. | 08-07-2014 |
20140304854 | METHODS FOR THE IDENTIFICATION OF GENES INVOLVED IN ABIOTIC STRESS TOLERANCE IN PLANTS - Methods are described for the identification of genes useful for conferring tolerance in plants to abiotic stress. Transgenic plants and seeds comprising the stress tolerant genes are also described. Methods to monitor the growth rate of the transgenic plants under stressed or non-stressed conditions are also described. | 10-09-2014 |
Yanlong Li, Newark, DE US
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20120040964 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess. | 02-16-2012 |
Yuhua Li, Newark, DE US
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20090202481 | Composition for Sustained Release Delivery of Proteins or Peptides - The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a protein or peptide in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) a protein or peptide covalently conjugated with one or more formulation performance-enhancing compounds. The present invention also provides a method of manufacturing and use of the composition thereof. | 08-13-2009 |
20100034801 | Non-Polymeric Compositions for Controlled Drug Delivery - The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a bioactive substance in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) an ionic complex that is formed between an amphiphilic molecule and a bioactive substance having a net charge at neutral pH in water. The present invention also provides a method of manufacturing and use of the composition thereof. | 02-11-2010 |
20120237476 | Pharmaceutical Compositions for Sustained Release Delivery of Peptides - The present invention provides methods of forming a solid, biodegradable implant in-situ in a body by administering a liquid pharmaceutical composition comprising an effective amount of a biocompatible, water-insoluble, biodegradable polymer and an effective amount of a therapeutic peptide covalently modified with one or more lipophilic or amphiphilic moieties, which are dissolved or dispersed in a biocompatible, water-soluble organic solvent. This invention also provides related compositions and methods. | 09-20-2012 |
Yun-Long Li, Wilmington, DE US
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20090176758 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 07-09-2009 |
20100119510 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 05-13-2010 |
20110212930 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 09-01-2011 |
20110224189 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES - The present invention provides compounds of the formula: | 09-15-2011 |
20120201816 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 08-09-2012 |
20140113892 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 04-24-2014 |
20150210691 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS - The present application describes lactam-containing compounds and derivatives thereof of Formula I: | 07-30-2015 |
Zhigang Rick Li, Hockessin, DE US
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20090035913 | HIGH-CAPACITANCE DENSITY THIN FILM DIELECTRICS HAVING COLUMNAR GRAINS FORMED ON BASE-METAL FOILS - Deposited thin-film dielectrics having columnar grains and high dielectric constants are formed on heat treated and polished metal foil. The sputtered dielectrics are annealed at low oxygen partial pressures. | 02-05-2009 |
20090238955 | PROCESSES FOR THE MANUFACTURE OF BARIUM TITANATE CAPACITORS ON NICKEL FOILS - Provided are processes for the manufacture of capacitors. It is found that by using a nickel foil as the substrate and one electrode of the capacitor and by controlling the oxygen partial pressure in the range of 10 | 09-24-2009 |
20110147677 | GLASS COMPOSITIONS USED IN CONDUCTORS FOR PHOTOVOLTAIC CELLS - The invention relates to zinc-containing glass compositions useful in conductive pastes for silicon semiconductor devices and photovoltaic cells. | 06-23-2011 |
20120152341 | LOW BOW ALUMINUM PASTE WITH AN ALKALINE EARTH METAL SALT ADDITIVE FOR SOLAR CELLS - The present invention relates to a composition for use as a backside conductive paste in solar cells. The paste comprises aluminum powder, an organic vehicle and an additive comprising a salt of an alkaline earth metal ion and an organic counterion. | 06-21-2012 |
20120312372 | GLASS COMPOSITIONS USED IN CONDUCTORS FOR PHOTOVOLTAIC CELLS - The invention relates to zinc-containing glass compositions useful in conductive pastes for silicon semiconductor devices and photovoltaic cells. | 12-13-2012 |
20120313198 | CONDUCTIVE PASTE COMPOSITION CONTAINING LITHIUM, AND ARTICLES MADE THEREFROM - A lead-free paste composition contains an electrically conductive silver powder, one or more glass frits or fluxes, and a lithium compound dispersed in an organic medium. The paste is useful in forming an electrical contact on the front side of a solar cell device having an insulating layer. The lithium compound aids in establishing a low-resistance electrical contact between the front-side metallization and underlying semiconductor substrate during firing. | 12-13-2012 |
20120325307 | LOW BOW ALUMINUM PASTE WITH AN ALKALINE EARTH METAL SALT ADDITIVE FOR SOLAR CELLS - Disclosed are aluminum paste compositions for forming an aluminum back electrode, processes to form aluminum back electrode of solar cells, and the solar cells so-produced. The aluminum paste composition has particulate aluminum and an additive wherein the additive is a salt of an alkaline earth metal ion and an organic counterion dispersed in an organic vehicle. | 12-27-2012 |
20130000714 | CONDUCTIVE PASTE COMPOSITION CONTAINING LITHIUM, AND ARTICLES MADE THEREFROM - A paste composition contains an electrically conductive silver powder, one or more glass frits or fluxes, and a lithium compound dispersed in an organic medium. The paste is useful in forming an electrical contact on the front side of a solar cell device having an insulating layer. The lithium compound aids in establishing a low-resistance electrical contact between the front-side metallization and underlying semiconductor substrate during firing. | 01-03-2013 |
20140061830 | CONDUCTIVE PASTE COMPOSITION AND SEMICONDUCTOR DEVICES MADE THEREWITH - A conductive paste composition contains a source of an electrically conductive metal, an alkaline-earth-metal boron tellurium oxide, and an organic vehicle. An article such as a high-efficiency photovoltaic cell is formed by a process of deposition of the paste composition on a semiconductor device substrate (e.g., by screen printing) and firing the paste to remove the organic vehicle and sinter the metal and establish electrical contact between it and the device. | 03-06-2014 |
20150068598 | CONDUCTIVE PASTE COMPOSITION AND SEMICONDUCTOR DEVICES MADE THEREWITH - A conductive paste composition contains a source of an electrically conductive metal, an alkaline-earth-metal boron tellurium oxide, and an organic vehicle. An article such as a high-efficiency photovoltaic cell is formed by a process of deposition of the paste composition on a semiconductor device substrate (e.g., by screen printing) and firing the paste to remove the organic vehicle and sinter the metal and establish electrical contact between it and the device. | 03-12-2015 |
Zusheng Li, Newark, DE US
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20130196011 | ANTIMICROBIAL BACTERIA STRAINS AND USES THEREOF - The present invention provides novel antimicrobial bacteria strains and uses thereof to prepare novel antimicrobial agents. Also provided are the novel antimicrobial agents. | 08-01-2013 |