Levitsky
Gershon Levitsky, Jersualem IL
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20140276179 | ENDOSCOPIC BITE BLOCK - According to a preferred embodiment of the present invention there is provided a bite block assembly adapted for capnography and oxygen delivery to a subject, the bite block assembly ( | 09-18-2014 |
20150250968 | ENDOSCOPIC BITE BLOCK - According to a preferred embodiment of the present invention there is provided a bite block assembly adapted for capnography and oxygen delivery to a subject, the bite block assembly ( | 09-10-2015 |
Hyam Levitsky, Owning Mills, MD US
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20160045597 | COMBINATION THERAPY OF ANTIBODIES ACTIVATING HUMAN CD40 AND ANTIBODIES AGAINST HUMAN PD-L1 - The present invention relates to a pharmaceutical product for the treatment of a proliferative disease, comprising the combination of an antibody, or an antigen-binding portion thereof, that specifically binds to human CD40; and a PD-L1 antibody; and optionally a 3 | 02-18-2016 |
Hyam I. Levitsky, Owing Hills, MD US
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20100272760 | CANCER IMMUNOTHERAPY WITH A VIRAL ANTIGEN-DEFINED, IMMUNOMODULATOR-SECRETING CELL VACCINE - A human cell line, which lacks major histocompatibility class I (MHC-I) antigens and major histocompatibility class II (MHC-II) antigens and which has been modified to comprise and express (i) a nucleotide sequence encoding an immunomodulator and (ii) a nucleotide sequence encoding a viral antigen, and a method of inducing or stimulating an immune response in a human to a viral-associated disease or cancer comprising administering to the human (i) the aforementioned human cell line in an amount sufficient to induce or stimulate an immune response to the viral associated disease or cancer, (ii) a human cell line, which lacks MHC-I and MHC-11 antigens and which has been modified to comprise and express a nucleotide sequence encoding an immunomodulator, and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral-associated disease or cancer, or (iii) an immunomodulator and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral associated disease or cancer. | 10-28-2010 |
Hyam I. Levitsky, Owings Mills, MD US
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20080260758 | UNIVERSAL GM-CSF EXPRESSING BYSTANDER HUMAN K562 CELL LINE - The present invention provides a universal immunomodulatory cytokine-expressing bystander cell line, a composition comprising such a cell line and a cancer antigen, a method of making such a cell line, and a method of using such a composition. | 10-23-2008 |
20110287058 | Universal GM-CSF Expressing Bystander Human Cell Line - The present invention provides a universal immunomodulatory cytokine-expressing bystander cell line, a composition comprising such a cell line and a cancer antigen, a method of making such a cell line, and a method of using such a composition. | 11-24-2011 |
Igor A. Levitsky, Fall River, MA US
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20100095743 | Amplified Sensitivity of Porous Chemosensors Based on Bernoulli Effect - A method of vapor sampling and its delivery to the porous sensory element(s) employed in chemical detectors/sensors for vapor(s) identification and quantification. The sampling and delivery system comprises a flow cell in which a sensory membrane is placed parallel to the flow, while an additional flow normal to the membrane is introduced using the Bernoulli effect. The bi-directional flow of vapors increases the interactions between the sensory material and vapor molecules, and enhances sensitivity. | 04-22-2010 |
20100213451 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS - The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer. | 08-26-2010 |
20100328646 | OPTICAL NANOPOROUS SENSORS FOR DETECTION OF WATER BASED VAPORS AND THEIR LEAKAGE FROM SEALED CONTAINERS - An optical sensor for detecting water vapors and water based vapors and comprising a semiconductor member having a semiconductor surface with hydrophilic pores therein. An illumination of the semiconductor surface by white light produces the reflectance spectral profile due to light spectral. The spectral profile is exposed to the water vapors and the change in the reflectance spectral response is measured during this exposure. | 12-30-2010 |
20110175035 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS - The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer. | 07-21-2011 |
20110194115 | Devices for Optochemical Detecting of Vapors and Particulates using Porous Photonic Crystals Infiltrated with Sensory Emissive Organics - An optochemical detector for detecting various chemical compounds and comprising a flow cell incorporating the sensory element constructed of an organic-inorganic emissive nanocomposite which luminescence spectral response is specific to exposed target vapors and particulates. The change in the luminescent spectral response is measured during this exposure. The detector is equipped with air-jet sampling system functioning in real-time mode for delivery of vapors and particulates to sensory element. | 08-11-2011 |
Igor Anatolievich Levitsky, Fall River, MA US
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20140212982 | METHODS OF SELECTIVELY DETECTING THE PRESENCE OF A COMPOUND IN A GASEOUS MEDIUM - Methods of selectively detecting the presence of at least one compound in a gaseous medium. A silicon substrate can be exposed to the gaseous medium under conditions to adsorb the at least one compound to the silicon substrate to form a modified silicon substrate. The modified silicon substrate can be analyzed to determine if the at least one compound was present in the gaseous medium. The step of analyzing can include using X-ray spectroscopy. | 07-31-2014 |
Konstantin Levitsky, Sausalito, CA US
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20110020925 | NEW MODULATING MOLECULES FOR AN IMPROVED REGULATED EXPRESSION SYSTEM - The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease. | 01-27-2011 |
Lynne L. Levitsky, Boston, MA US
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20120094375 | ENHANCED ENGINEERED NATIVE PROMOTERS AND USES THEREOF - We describe methods and DNA constructs/engineered mammalian promoters to enhance native promoter activity while retaining inherent regulation by inserting multi-copy response elements (REs) into non-adjacent locations. Multiple copies of REs are clustered in a group forming a transcription factor response element segment. The segment is at least duplicated in tandem upstream of the ATG start codon. Spacers of 0.2-0.7 kilo base pairs are introduced between the two segments and smaller spacers of about between 9-15 by are introduced between the copies of REs within a segment. | 04-19-2012 |
Michael Levitsky, Petah Tikva IL
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20130177061 | Fast Acquisition Of Frame Timing And Frequency - Modern digital signals include framing. A known sequence of transmission symbols (Unique Word (UW)) included in the transmitted signal may be used by a receiver for framing synchronization. A receiver configured to receive such a signal may be configured to detect the UW even when the signal is received with some frequency uncertainty (e.g. offset or error). A method is presented for fast acquisition of symbol and/or frame timing of a signal, including in the presence of frequency uncertainty. In some embodiments, the presented method may be used for determining a frequency offset of the received signal and a location of a unique word (UW) within a frame of the received signal, wherein said determining is based on a two-dimensional search map. | 07-11-2013 |
Michael Levitsky, Beer Sheva IL
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20090014555 | Light Cleaning Device for a Vehicle - A light cleaning device for washing lights located on an external portion of a vehicle. The device has an elongate housing formed with an inlet port connectable to a source of pressurized liquid and a rinsing head fitted with at least one jet nozzle. The jet nozzle is mounted at a distal end of a telescopically retractable hollow tube of the device, which is normally retracted. There is a liquid flow path from the housing to the rinsing head which can emit a jet spray therefrom when the tube is projected from the housing. The nozzle may have a jet forming member fitted therein to turbulate the jet spray fluid. | 01-15-2009 |
20090078795 | Liquid Atomizer for Agricultural Applications - A liquid atomizer for agricultural use includes at least one canal in fluid communication via a chamber with an outlet. At least a section of the canal extends along a straight line and tangentially opens into the chamber. | 03-26-2009 |
20120126030 | LIGHT CLEANING DEVICE FOR A VEHICLE - Provided is a light cleaning device for washing lights located on an external portion of a vehicle. The device has an elongate housing formed with an inlet port connectable to a source of pressurized liquid and a rinsing head fitted with at least one jet nozzle. The jet nozzle is mounted at a distal end of a telescopically retractable hollow tube of the device, which is normally retracted. There is a liquid flow path from the housing to the rinsing head which can emit a jet spray therefrom when the tube is projected from the housing. The nozzle may have a jet forming member fitted therein to turbulate the jet spray fluid. | 05-24-2012 |
20120126031 | LIGHT CLEANING DEVICE FOR A VEHICLE - Provided is a light cleaning device for washing lights located on an external portion of a vehicle. The device has an elongate housing formed with an inlet port connectable to a source of pressurized liquid and a rinsing head fitted with at least one jet nozzle. The jet nozzle is mounted at a distal end of a telescopically retractable hollow tube of the device, which is normally retracted. There is a liquid flow path from the housing to the rinsing head which can emit a jet spray therefrom when the tube is projected from the housing. The nozzle may have a jet forming member fitted therein to turbulate the jet spray fluid. | 05-24-2012 |
Oleg Levitsky, San Jose, CA US
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20090172619 | METHOD AND SYSTEM FOR IMPLEMENTING TIMING ANALYSIS AND OPTIMIZATION OF AN ELECTRONIC DESIGN BASED UPON EXTENDED REGIONS OF ANALYSIS - Operations are performed in EDA tools that operate upon partitions or discrete portions of an electronic design, in which the partitions or discrete portions of the design are expanded to account for effects to/from other areas in the design. Identification is made of the portions of the design that are external to the partitions, and depending upon the type of expected effects, would then be considered during optimization and analysis of the partitions. This is implemented by logically expanding the partition to include consideration of the external portions during timing optimization and analysis. By considering an expanded partition for timing optimization and analysis, it is possible to identify unintended problems caused by the timing optimization at an earlier stage of the design process. | 07-02-2009 |
20120254818 | METHODS, SYSTEMS, AND ARTICLES OF MANUFACTURE FOR IMPLEMENTING FULL-CHIP OPTIMIZATION WITH REDUCED PHYSICAL DESIGN DATA - Disclosed are methods, systems, and articles of manufacture for implementing full-chip optimization across block boundaries with reduced physical design data. Some embodiments create a partial netlist and reduced physical data by identifying and including side instance(s) or side path(s) in the reduced physical data and then include or exclude side instance(s) or side path(s) in the reduced physical data. The method or the system may then perform full-chip optimization across individual block boundaries with the reduced physical data. Some embodiments further merge the post-optimization data back into the original data while reducing logic and physical disturbance to existing designs. Some embodiments anchor driver instance(s) that correspond to excluded side instance(s) or side path(s) to ensure LEC cleanliness and may further trim timing graph(s) based at least on the partial netlist. Some embodiments account for parasitics without static parasitic files. Various embodiments apply to both hierarchical and non-hierarchical designs. | 10-04-2012 |
Valery Levitsky, Nepean CA
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20120192283 | Interlocked Binary Protection Using Whitebox Cryptography - A system and method for transforming a software application comprising binary code and optionally associated data, from an original form to a more secure form. The method includes performing a combination of binary transmutations to the application, and interlocking the transmutations by generating and placing interdependencies between the transmutations, wherein a transmutation is an irreversible change to the application. Different types of the transmutations are applied at varied granularities of the application. The transmutations are applied to the application code and the implanted code as well. The result is a transformed software application which is semantically equivalent to the original software application but is resistant to static and/or dynamic attacks. | 07-26-2012 |