Patent application number | Description | Published |
20090093398 | Use of Fibroblast Growth Factor Fragments - A discovery process beginning with an in vivo screening of proteins, peptides, natural products, classical medicinal compound or other substances. The administration of compounds to the animal can be either direct or indirect, such as by the administration and expression of cDNA-containing plasmids. Since the discovery process of the invention is based on a non-preconceived hypothesis and whole organism multi-organ analysis, a compound can be selected for testing in the absence of any biological selection criteria. The resulting organism-wide pattern of the gene expression changes in the transcriptome provides an overview of the activities at the molecular and organism-wide levels. The discovery process of the invention then integrates in vivo profiling and internal and external genomic databases to elucidate the function of unknown proteins, typically within few months. The invention further relates to medical uses of fibroblast growth factor 23 (FGF-23), FGF-23 fragments, FGF-23 C-terminal polypeptides, FGF-23 homologs and/or FGF-23 variants. | 04-09-2009 |
20100216254 | DRUG MONITORING ASSAY - A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided. | 08-26-2010 |
20120028896 | USE OF FIBROBLAST GROWTH FACTOR FRAGMENTS - A discovery process beginning with an in vivo screening of proteins, peptides, natural products, classical medicinal compound or other substances. The administration of compounds to the animal can be either direct or indirect, such as by the administration and expression of cDNA-containing plasmids. Since the discovery process of the invention is based on a non-preconceived hypothesis and whole organism multi-organ analysis, a compound can be selected for testing in the absence of any biological selection criteria. The resulting organism-wide pattern of the gene expression changes in the transcriptome provides an overview of the activities at the molecular and organism-wide levels. The discovery process of the invention then integrates in vivo profiling and internal and external genomic databases to elucidate the function of unknown proteins. The invention further relates to medical uses of fibroblast growth factor 23 (FGF-23), FGF-23 fragments, FGF-23 C-terminal polypeptides, FGF-23 homologs and/or FGF-23 variants. | 02-02-2012 |
20120115247 | DRUG MONITORING ASSAY - A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided. | 05-10-2012 |
20130040882 | USE OF FIBROBLAST GROWTH FACTOR FRAGMENTS - A discovery process beginning with an in vivo screening of proteins, peptides, natural products, classical medicinal compound or other substances. The administration of compounds to the animal can be either direct or indirect, such as by the administration and expression of cDNA-containing plasmids. Since the discovery process of the invention is based on a non-preconceived hypothesis and whole organism multi-organ analysis, a compound can be selected for testing in the absence of any biological selection criteria. The resulting organism-wide pattern of the gene expression changes in the transcriptome provides an overview of the activities at the molecular and organism-wide levels. The discovery process of the invention then integrates in vivo profiling and internal and external genomic databases to elucidate the function of unknown proteins, typically within few months. The invention further relates to medical uses of fibroblast growth factor 23 (FGF-23), FGF-23 fragments, FGF-23 C-terminal polypeptides, FGF-23 homologs and/or FGF-23 variants. | 02-14-2013 |
Patent application number | Description | Published |
20100085272 | Reflector Array and Antenna Comprising Such a Reflector Array - A reflector array comprises a plurality of individual radiating elements forming a reflecting surface with no abrupt transitions wherein each radiating element of the reflecting surface is selected from a set of predetermined consecutive radiating elements, called the pattern, the first and last elements of the pattern correspond to one and the same phase, modulo 360°, and are identical, and the radiating elements of the pattern have a radiating structure, of metal patch type and/or of radiating aperture type, that progressively changes from one radiating element to another adjacent radiating element, the change in the radiating structure comprising a succession of progressive growths of at least one metal patch and/or at least one aperture and appearances of at least one metal patch in an aperture and/or at least one aperture in a metal patch. | 04-08-2010 |
20100097290 | Reconfigurable Radiant Array Antenna - The invention relates to a reconfigurable reflecting array antenna comprising a subset of patterns capable of radiating signals emitted in a given direction and means of loading and placing said radiating arrays to place one of them in a chosen emitting position, characterized in that:
| 04-22-2010 |
20100156725 | Dual Polarization Planar Radiating Element and Array Antenna Comprising Such a Radiating Element - A dual-polarization planar radiating element having an external metal grid, at least one metal patch concentric with the external metal grid and a cavity separating the metal grid and the metal patch, the grid and the patch having a polygonal shape delimited by at least four pairwise opposite sides, and two orthogonal directions of polarization associated with two orthogonal electric fields Ev and Eh, at least one of the directions of polarization being parallel to two sides of the polygon. Each side of the metal patch parallel to a direction of polarization is linked electrically to a zone of the external grid where one of the electric fields Ev or Eh is a minimum. The invention exhibits the advantage of reducing the phenomenon of electrostatic discharges in the planar radiating elements without significantly modifying the response of the radiating element subjected to an orthogonally polarized wave. | 06-24-2010 |
20130099990 | REFLECTOR ARRAY ANTENNA WITH CROSSED POLARIZATION COMPENSATION AND METHOD FOR PRODUCING SUCH AN ANTENNA - A reflector array antenna with cross-polarization compensation including at least one radiating element having an etched pattern dissymmetric with respect to at least one direction X and/or Y of the plane XY of the radiating element, the dissymmetry of the pattern of the radiating element being calculated individually on the basis of a radiating element of the same symmetric pattern along the two directions X and Y, so as to engender a reflected wave having a controlled depolarization which opposes a depolarization, engendered in a plane normal to a direction of propagation, by the reflector array illuminated by a primary source . | 04-25-2013 |
20130207859 | COMPACT RADIATING ELEMENT HAVING RESONANT CAVITIES - A radiating element is provided, for example for array antenna, having stacked resonant cavities of Pérot-Fabry type, of compact structure, a lower cavity being fed by excitation means, the radiating element being characterized in that corrugations are formed substantially below a first earth plane delimiting in its lower part the upper resonant cavity. A radiating element structure of improved compactness is also proposed, whose upper cavity is surmounted by a polarizing radome. | 08-15-2013 |
20130241770 | Reconfigurable Radiating Phase-Shifting Cell Based on Complementary Slot and Microstrip Resonances - A radiating phase-shifting cell is designed to favour the excitation of an equivalent resonance of the “slot” type in a first part of the phase cycle, and to favour an equivalent resonance of the “microstrip” type in a second part of the phase cycle. This property notably allows the bandwidth of the phase-shifting cells to be optimized. A phase range of 360° can in effect be segmented into two sub-ranges of around 180°. This segmentation into two sub-ranges is made possible by the complementarity of the resonant modes of the slot or microstrip type. The radiating phase-shifting cell is notably applicable to reflector arrays for an antenna designed to be installed on a space craft such as a telecommunications satellite or on a terrestrial terminal for satellite telecommunications or broadcasting systems. | 09-19-2013 |
20140354499 | TWO-DIMENSIONAL MULTI-BEAM FORMER, ANTENNA COMPRISING SUCH A MULTI-BEAM FORMER AND SATELLITE TELECOMMUNICATION SYSTEM COMPRISING SUCH AN ANTENNA - A multi-beam former comprises: two stages connected together and intended to synthesize beams focused along two directions in space; each stage comprises at least two multi-layer plane structures, superposed one above the other; each multi-layer structure comprises an internal reflector, at least two first internal sources disposed in front of the internal reflector and linked to two input/output ports aligned along an axis, at least two second internal sources disposed in a focal plane of the internal reflector and linked to two second input/output ports aligned along an axis perpendicular to the axis; the two second internal sources of the same multi-layer structure of the first stage are respectively linked to two first internal sources of two different multi-layer structures of the second stage. | 12-04-2014 |
Patent application number | Description | Published |
20100085272 | Reflector Array and Antenna Comprising Such a Reflector Array - A reflector array comprises a plurality of individual radiating elements forming a reflecting surface with no abrupt transitions wherein each radiating element of the reflecting surface is selected from a set of predetermined consecutive radiating elements, called the pattern, the first and last elements of the pattern correspond to one and the same phase, modulo 360°, and are identical, and the radiating elements of the pattern have a radiating structure, of metal patch type and/or of radiating aperture type, that progressively changes from one radiating element to another adjacent radiating element, the change in the radiating structure comprising a succession of progressive growths of at least one metal patch and/or at least one aperture and appearances of at least one metal patch in an aperture and/or at least one aperture in a metal patch. | 04-08-2010 |
20100156725 | Dual Polarization Planar Radiating Element and Array Antenna Comprising Such a Radiating Element - A dual-polarization planar radiating element having an external metal grid, at least one metal patch concentric with the external metal grid and a cavity separating the metal grid and the metal patch, the grid and the patch having a polygonal shape delimited by at least four pairwise opposite sides, and two orthogonal directions of polarization associated with two orthogonal electric fields Ev and Eh, at least one of the directions of polarization being parallel to two sides of the polygon. Each side of the metal patch parallel to a direction of polarization is linked electrically to a zone of the external grid where one of the electric fields Ev or Eh is a minimum. The invention exhibits the advantage of reducing the phenomenon of electrostatic discharges in the planar radiating elements without significantly modifying the response of the radiating element subjected to an orthogonally polarized wave. | 06-24-2010 |
20130099990 | REFLECTOR ARRAY ANTENNA WITH CROSSED POLARIZATION COMPENSATION AND METHOD FOR PRODUCING SUCH AN ANTENNA - A reflector array antenna with cross-polarization compensation including at least one radiating element having an etched pattern dissymmetric with respect to at least one direction X and/or Y of the plane XY of the radiating element, the dissymmetry of the pattern of the radiating element being calculated individually on the basis of a radiating element of the same symmetric pattern along the two directions X and Y, so as to engender a reflected wave having a controlled depolarization which opposes a depolarization, engendered in a plane normal to a direction of propagation, by the reflector array illuminated by a primary source . | 04-25-2013 |
20130207859 | COMPACT RADIATING ELEMENT HAVING RESONANT CAVITIES - A radiating element is provided, for example for array antenna, having stacked resonant cavities of Pérot-Fabry type, of compact structure, a lower cavity being fed by excitation means, the radiating element being characterized in that corrugations are formed substantially below a first earth plane delimiting in its lower part the upper resonant cavity. A radiating element structure of improved compactness is also proposed, whose upper cavity is surmounted by a polarizing radome. | 08-15-2013 |
Patent application number | Description | Published |
20100160989 | Implantable Cardiac Prosthesis Generator Having Protection From an MRI Examination - A generator for an implantable cardiac prosthesis, having a safekeeping mode of operation during an exposure to a magnetic field. The generator is connected to a lead including a first conductor ( | 06-24-2010 |
20110178562 | System and Method For Protecting Against Magnetic Fields Produced By MRI - An implantable cardiac device that detects and protects against strong magnetic fields produced by MRI equipment is disclosed. The device has a magnetic field sensor for detecting the presence of a relatively weak static magnetic field ( | 07-21-2011 |
20140039568 | DETECTION OF STRONG STATIC MAGNETIC FIELDS AND MRI EXAMINATION SAFEKEEPING FOR AN IMPLANTABLE CARDIAC PROSTHESIS - An implantable medical device detects a strong static magnetic field associated with an MRI imaging instrument and operates in a safekeeping operating mode. The device includes an electronic circuit for the detection/stimulation of a cardiac activity, a weak field sensor detecting the presence of a first magnetic field of a permanent magnet being located in proximity to the device, a strong field sensor detecting the presence of a second magnetic field of an MRI imaging instrument during the course of an MRI examination. | 02-06-2014 |
20140052200 | IMPLANTABLE CARDIAC PROSTHESIS GENERATOR HAVING PROTECTION FROM AN MRI EXAMINATION - Systems, methods, and devices for protecting against effects of magnetic fields are provided. One implantable medical device includes a lead including a first conductor and a second conductor. The device further includes a generator including an electronic circuit, a metal housing that has a ground potential, and one or more switching devices. The switching devices, in a safekeeping configuration, are configured to disconnect the second conductor from the electronic circuit and to connect the second conductor to the ground potential of the metal housing. The first conductor is connected to the electronic circuit in the safekeeping configuration. The switching devices, in the safekeeping configuration, are configured to cause the second conductor to shield the first conductor from at least a portion of the effects of the magnetic field while the first conductor remains connected to the electronic circuit for use in performing a sensing operation and/or a stimulation operation. | 02-20-2014 |
20140364921 | ACTIVE IMPLANTABLE MEDICAL DEVICE FOR HEART FAILURE THERAPY WITH STOCHASTIC STIMULATION OF THE VAGUS NERVE - A method for heart treatment includes analyzing the cardiac rhythm. The method further includes utilizing a generator to produce discharges (S | 12-11-2014 |
20140364923 | ACTIVE IMPLANTABLE MEDICAL DEVICE FOR NEURAL THERAPY WITH STOCHASTIC STIMULATION OF THE VAGUS NERVE - This device comprises a generator producing bursts (Si) of N pulses (I) of VNS stimulation generated in succession during respective periods of activity (TON) separated by intermediate periods of inactivity (TOFF) during which no stimulation is issued. Stochastic modulation means control the delivery of the bursts of each of the N pulses of each VNS burst by selective inhibition or not, of the generation of each of said VNS pulses depending on the result of a respective randomization. The number of VNS pulses of each burst is thus randomly varying, and thus the VNS stimulation energy of this burst and the interval between successive pulses, which counteract the appearance of a physiological compensation loop. | 12-11-2014 |