Lee, Newton
Gordon H. Lee, Newton, PA US
Patent application number | Description | Published |
---|---|---|
20140378720 | Processes to Produce Polyalpha-Olefin Compositions - A process to produce polyalpha-olefins includes contacting a feed stream of at least one alpha-olefin monomer having 4 to 25 carbon atoms with a metallocene catalyst compound and an activator, and optionally an alkyl-aluminum compound, under polymerizations conditions in a reactor. The alpha-olefin monomer is present at 10% volume or more in the reactor and the feed stream includes less than 600 ppm of heteroatom containing compounds. The process further includes obtaining a polyalpha-olefin with at least 50 mole % C5 to C24 alpha-olefin monomer and kinematic viscosity at 100° C. of 5000 cSt or less. | 12-25-2014 |
Gwo-Shu Mary Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20130095481 | METHODS FOR PREDICTING LIKELIHOOD OF RESPONDING TO TREATMENT - The disclosure provides materials and methods related to using biomarkers for prediction of duration of response to prostate cancer treatment and for treating prostate cancer. | 04-18-2013 |
Heon Ju Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20130199600 | ARTICLES, SYSTEMS, AND METHODS RELATING TO THERMAL STABILITY OF NANOSTRUCTURED AND/OR MICROSTRUCTURED MATERIALS - The present invention generally relates to articles, systems, and methods relating to the thermal stability of nanostructured and/or microstructured materials. | 08-08-2013 |
Janet Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20100153245 | SYSTEM AND METHOD FOR REAL-TIME ACTIVITY-BASED ACCOUNTING - An accounting method and system is disclosed that provides for real time financial accounting of plant performance at a sub-plant level. A multiplicity of process variable transmitters is utilized to sense, in real time, the current state of the processes and process equipment used in a manufacturing plant. Sub-plant accounting modules utilize the sensed process data to calculate a plurality of sub-plant accounting measures, which are stored in one or more real time plant historian. The accounting measures are typically converted to a suitable format and subsequently stored in a production model accounting database where they are accessible to an accounting module. | 06-17-2010 |
Ju Hee Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20150057751 | ACELLULAR DERMAL GRAFT - An acellular dermal graft is provided. The acellular dermal graft may be useful in minimizing side effects caused after transplantation since an environment favorable for formation of new blood vessels and proliferation of autologous tissues is provided by forming a multi-penetration structure in an acellular dermal tissue, removing a basement membrane layer and/or subjecting corners to slope cutting, and transplantation is stably performed within a short transplantation time due to improved extensibility and flexibility of tissues. The acellular dermal graft may be useful in reducing a time required to recover tissues after transplantation since the transplantation is stably performed due to improved grafting reaction with a host tissue by enhancing uptake of fibroblasts and promoting angiogenic activities. Also, the acellular dermal graft may be useful in maintaining smooth external appearance since hypodermic implantation is easily performed upon transplantation, and the skin at a graft site does not protrude after transplantation. | 02-26-2015 |
Katherine L. Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20100022536 | Inhibitors of Cytosolic Phospholipase A2 - This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A | 01-28-2010 |
20100029645 | Inhibitors of Cytosolic Phospholipase A2 - This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A | 02-04-2010 |
Kayi Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20120166182 | Autocompletion for Partially Entered Query - A server system receives, respectively, a first character string from a first user and a second character string from a second user. There are one or more differences between the first and second character strings. The server system obtains from a plurality of previously submitted complete queries, respectively, a first set of predicted complete queries corresponding to the first character string and a second set of predicted complete queries corresponding to the second character string. There are one or more identical queries in both the first and second sets. The server system conveys at least a first subset of the first set to the first user and at least a second subset of the second set to the second user. Both the first subset and the second subset include a respective identical query. | 06-28-2012 |
Kichang Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20130296693 | RIGHT ATRIUM INDICATOR - A method for determining the location of a medical device within a body is provided. The method includes transmitting from the medical device an acoustic signal; receiving with the medical device a reflected acoustic signal; advancing the medical device based on a first algorithm, the first algorithm including a first weighting factor and a first feature extracted from the reflected acoustic signal; determining a first location of the medical device based on the first algorithm; and moving the medical device to a second location based on a second algorithm, the second algorithm based on the determined first location and including at least one of a second weighting factor and a second feature extracted from the reflected acoustic signal. Also disclosed are systems and devices for performing the methods described herein. | 11-07-2013 |
20130296725 | SYSTEMS AND METHODS FOR DETECTION OF THE SUPERIOR VENA CAVA AREA AND THE CAVOATRIAL JUNCTION - Described herein are systems, devices and methods to increase the accuracy of intravascular catheter placement, and to improve electrocardiogram (ECG), intravascular electrogram, and ultrasound Doppler signal processing to detect the Superior Vena Cava (SVC) area. Embodiments of the invention are intended to place an intravascular catheter within the lower ⅓ of SVC to the junction of the SVC and the right atrium (RA)—called the cavoatrial junction (CAJ). In particular, the improved accuracy of CAJ location detection during an intravascular catheter placement can be provided by optimization of ECG parameters and ultrasound Doppler signal using Neuro-Fuzzy logic and/or other processing techniques. | 11-07-2013 |
Kyungae Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20080227793 | Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I | 09-18-2008 |
20090176980 | 3-Substituted-6-Aryl Pyridines - 3-substituted-6-aryl pyridines of Formula I are provided: | 07-09-2009 |
20110034463 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF - The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as | 02-10-2011 |
20110160187 | 3-aryl-5,6-disubstituted pyridazines - The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions. | 06-30-2011 |
20110281837 | 3-SUBSTITUTED-6-ARYL PYRIDINES - 3-substituted-6-aryl pyridines of Formula I are provided: | 11-17-2011 |
20120046282 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION - The present invention provides Wall Teichoic Acid biosynthesis inhibitors such as compound 1835F03 (targocil) and related synthetic analogs. The invention also provides pharmaceutical compositions thereof and methods for treating bacterial infection and the suppression of growth of bacterial cells by administering a Wall Teichoic Acid biosynthesis inhibitor. The invention is particularly useful for the treatment of Methicillin-resistant | 02-23-2012 |
20130231332 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE - The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses. | 09-05-2013 |
20140323483 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF - The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as | 10-30-2014 |
20140329834 | Small Molecule Inhibitors of Ebola and Lassa Fever Viruses - The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses. | 11-06-2014 |
Mei Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20090012020 | Inhibiting formation of atherosclerotic lesions - The invention features a method of inhibiting formation of atherosclerotic lesions by administering to a mammal, e.g., a human patient who has been identified as suffering from or at risk of developing atherosclerosis, a compound that reduces expression or activity of AFABP. | 01-08-2009 |
Mu-En Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20090012020 | Inhibiting formation of atherosclerotic lesions - The invention features a method of inhibiting formation of atherosclerotic lesions by administering to a mammal, e.g., a human patient who has been identified as suffering from or at risk of developing atherosclerosis, a compound that reduces expression or activity of AFABP. | 01-08-2009 |
Sam Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20110053938 | Compounds and Compositions For Treating Cancer - The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed. | 03-03-2011 |
20120059004 | Compounds And Compositions For Treating Cancer - The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed. | 03-08-2012 |
20120157455 | Compounds And Compositions For Treating Cancer - The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed. | 06-21-2012 |
Samuel Soonho Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20140341346 | X-RAY TUBE AND RECEIVER INSIDE MOUTH - A method and a device for low x-ray radiation dosage while taking x-ray images of a patient's teeth is disclosed. The method includes use of an x-ray source and receiver positioned at least partially inside the patient's mouth. The device includes an x-ray source and receiver attached together by a bite holder and configured to both be disposed at least partially inside the patient's mouth across a tooth while taking x-ray images of a patient's tooth. | 11-20-2014 |
Sam W. Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20090312373 | METHODS FOR THE TREATMENT OF CANCER USING PIPERLONGUMINE AND PIPERLONGUMINE ANALOGS - The invention provides methods for the treatment of cancer in a subject using piperlongumine and/or piperlongumine analogs. | 12-17-2009 |
20110060047 | APPROACHES TO TREAT CANCER USING HB-EGF INHIBITORS - The invention provides methods for the treatment of cancer in a subject by the administration of myrsinoic acid A and/or one or more myrsinoic acid A analogs. | 03-10-2011 |
20110091387 | METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE - The RhoE GTPase pathway has been identified as a target for screening and treatment methods for the prevention and/or reduction of short- and long-term UVB-induced skin damage, e.g., the prevention and/or reduction of UVB-induced wrinkles. The invention thus features screening and treatment methods for prevention or reduction of UVB-induced sin damage, and related compositions, e.g., cosmetic compositions. | 04-21-2011 |
20110189318 | METHODS FOR ENHANCING THE EXPRESSION OF INTRACELLULAR REDOX-ASSOCIATED FACTORS - The present invention provides methods for enhancing expression of a redox-associated factor, wherein kaempferol, quercetin or glycosides thereof, or any combination thereof is used as an active ingredient, and methods for enhancing expression of a redox-associated factor wherein ginkgo leaf extract, | 08-04-2011 |
20130203757 | Compounds And Compositions For Treating Cancer - The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed. | 08-08-2013 |
20130237539 | Compounds and Compositions for Treating Cancer - The invention relates to compounds and composition for the treatment and prevention of cancer. The invention also covers all diseases that may be treated by selective modulation of levels of reactive oxygen species in diseased cells versus normal cells. Methods for the preparation and administration of such compositions are also disclosed. | 09-12-2013 |
20140186277 | Methods and Compositions for Reducing Skin Damage - The RhoE GTPase pathway has been identified as a target for screening and treatment methods for the prevention and/or reduction of short- and long-term UVB-induced skin damage, e.g., the prevention and/or reduction of UVB-induced wrinkles. The invention thus features screening and treatment methods for prevention or reduction of UVB-induced skin damage, and related compositions, e.g., cosmetic compositions. | 07-03-2014 |
20150079107 | AGENTS AND METHODS FOR TREATING AND PREVENTING SEBORRHEIC KERATOSIS - Provided herein are methods and assays for isolating and culturing seborrheic keratosis cells ex vivo. Also provided herein are screening assays using cultured seborrheic keratosis cells and methods for treating seborrheic keratosis in a subject. | 03-19-2015 |
Stephanie Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20160000413 | OPTICALLY AUGMENTED FINE NEEDLE ASPIRATION BIOPSY DEVICE AND METHOD OF USING THE SAME - Devices for performing fine-needle aspiration of tissue and methods of using the same are disclosed. The device includes a syringe including a fiber optic probe, a plunger, and a needle and a holder including a coupling mechanism, a first actuator, and a second actuator. The fiber optic probe is configured to move within a lumen of the needle and is guided into the needle by a fiber optic channel. The plunger is configured to create a vacuum in the needle. | 01-07-2016 |
Tzehin Lee, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20080238255 | VIBRATION ASSISTED MACHINING SYSTEM WITH STACKED ACTUATORS - A vibration assisted machining (VAM) system, including: a frame; a vibration element mechanically coupled to the frame; a cutting tool holder connected to the vibration element; and a workpiece holder coupled to the frame. The vibration element includes a first piezoelectric (PZT) actuator and a second PZT actuator, which are adapted to generate a substantially elliptical tool path in a vibration plane of the VAM system. The VAM system also includes a third PZT actuator coupled between the frame and either the vibration element or the workpiece holder. This third PZT actuator is coupled to the frame such that its polarization axis is substantially in the vibration plane and substantially perpendicular to the feed direction of the VAM system. | 10-02-2008 |