Patent application number | Description | Published |
20100106356 | Control and systems for autonomously driven vehicles - A navigation and control system including one or more position sensors configured to generate position signals indicative of the location and heading of a vehicle. The system includes one or more operation control mechanisms having inputs and producing outputs which control an operation of the vehicle and includes a self-contained autonomous controller disposed remote from the operation control mechanisms. The autonomous controller includes a processor configured to receive the position signals from the position sensors and to generate operation control signals defining an updated travel path for the vehicle, and a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The programmable interface is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms, whereby the self-contained autonomous controller is configurable for operation with a variety of different sensors and different operation control mechanisms. | 04-29-2010 |
20120101680 | CONTROL AND SYSTEMS FOR AUTONOMOUSLY DRIVEN VEHICLES - An autonomous controller for a vehicle. The controller has a processor configured to receive position signals from position sensors and to generate operation control signals defining an updated travel path for the vehicle. The controller has a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The controller is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms. The processor and the programmable interface define a self-contained unit configurable for operation with a variety of different remote sensors and different remote operation control mechanisms. | 04-26-2012 |
20120316725 | CONTROL AND SYSTEMS FOR AUTONOMOUSLY DRIVEN VEHICLES - An autonomous controller for a vehicle. The controller has a processor configured to receive position signals from position sensors and to generate operation control signals defining an updated travel path for the vehicle. The controller has a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The controller is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms. The processor and the programmable interface define a self-contained unit configurable for operation with a variety of different remote sensors and different remote operation control mechanisms. | 12-13-2012 |
20130274986 | CONTROL AND SYSTEMS FOR AUTONOMOUSLY DRIVEN VEHICLES - An autonomous controller for a vehicle. The controller has a processor configured to receive position signals from position sensors and to generate operation control signals defining an updated travel path for the vehicle. The controller has a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The controller is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms. The processor and the programmable interface define a self-contained unit configurable for operation with a variety of different remote sensors and different remote operation control mechanisms. | 10-17-2013 |
20140214259 | CONTROL AND SYSTEMS FOR AUTONOMOUSLY DRIVEN VEHICLES - An autonomous controller for a vehicle. The controller has a processor configured to receive position signals from position sensors and to generate operation control signals defining an updated travel path for the vehicle. The controller has a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The controller is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms. The processor and the programmable interface define a self-contained unit configurable for operation with a variety of different remote sensors and different remote operation control mechanisms. | 07-31-2014 |
20150081156 | CONTROL AND SYSTEMS FOR AUTONOMOUSLY DRIVEN VEHICLES - An autonomous controller for a vehicle. The controller has a processor configured to receive position signals from position sensors and to generate operation control signals defining an updated travel path for the vehicle. The controller has a programmable interface providing communication among the position sensors, the operation control mechanisms, and the processor. The controller is configured to normalize inputs to the processor from the position sensors and to generate compatible operation control signals applied as the inputs to the operation control mechanisms. The processor and the programmable interface define a self-contained unit configurable for operation with a variety of different remote sensors and different remote operation control mechanisms. | 03-19-2015 |
Patent application number | Description | Published |
20110034677 | RECURRENT GENE FUSIONS IN PROSTATE CANCER - Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. | 02-10-2011 |
20110110923 | FISH ASSAY FOR EML4 AND ALK FUSION IN LUNG CANCER - Methods and compositions provided relate to conducting a FISH assay for detecting a chromosomal inversion between EML4 and ALK. The FISH assay described herein is useful for diagnostic and prognostic purposes, as well as for determination of therapeutic strategies. | 05-12-2011 |
20120295809 | RECURRENT GENE FUSIONS IN PROSTATE CANCER - Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. | 11-22-2012 |
20120296070 | RECURRENT GENE FUSIONS IN PROSTATE CANCER - Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. | 11-22-2012 |
20130040858 | RECURRENT GENE FUSIONS IN PROSTATE CANCER - Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. | 02-14-2013 |
Patent application number | Description | Published |
20080229415 | SYSTEMS AND METHODS FOR PROCESSING DATA FLOWS - A flow processing facility, which uses a set of artificial neurons for pattern recognition, such as a self-organizing map, in order to provide security and protection to a computer or computer system supports unified threat management based at least in part on patterns relevant to a variety of types of threats that relate to computer systems, including computer networks. Flow processing for switching, security, and other network applications, including a facility that processes a data flow to address patterns relevant to a variety of conditions are directed at internal network security, virtualization, and web connection security. A flow processing facility for inspecting payloads of network traffic packets detects security threats and intrusions across accessible layers of the IP-stack by applying content matching and behavioral anomaly detection techniques based on regular expression matching and self-organizing maps. Exposing threats and intrusions within packet payload at or near real-time rates enhances network security from both external and internal sources while ensuring security policy is rigorously applied to data and system resources. Intrusion Detection and Protection (IDP) is provided by a flow processing facility that processes a data flow to address patterns relevant to a variety of types of network and data integrity threats that relate to computer systems, including computer networks. | 09-18-2008 |
20080262990 | SYSTEMS AND METHODS FOR PROCESSING DATA FLOWS - A flow processing facility, which uses a set of artificial neurons for pattern recognition, such as a self-organizing map, in order to provide security and protection to a computer or computer system supports unified threat management based at least in part on patterns relevant to a variety of types of threats that relate to computer systems, including computer networks. Flow processing for switching, security, and other network applications, including a facility that processes a data flow to address patterns relevant to a variety of conditions are directed at internal network security, virtualization, and web connection security. A flow processing facility for inspecting payloads of network traffic packets detects security threats and intrusions across accessible layers of the IP-stack by applying content matching and behavioral anomaly detection techniques based on regular expression matching and self-organizing maps. Exposing threats and intrusions within packet payload at or near real-time rates enhances network security from both external and internal sources while ensuring security policy is rigorously applied to data and system resources. Intrusion Detection and Protection (IDP) is provided by a flow processing facility that processes a data flow to address patterns relevant to a variety of types of network and data integrity threats that relate to computer systems, including computer networks. | 10-23-2008 |
20080262991 | SYSTEMS AND METHODS FOR PROCESSING DATA FLOWS - A flow processing facility, which uses a set of artificial neurons for pattern recognition, such as a self-organizing map, in order to provide security and protection to a computer or computer system supports unified threat management based at least in part on patterns relevant to a variety of types of threats that relate to computer systems, including computer networks. Flow processing for switching, security, and other network applications, including a facility that processes a data flow to address patterns relevant to a variety of conditions are directed at internal network security, virtualization, and web connection security. A flow processing facility for inspecting payloads of network traffic packets detects security threats and intrusions across accessible layers of the IP-stack by applying content matching and behavioral anomaly detection techniques based on regular expression matching and self-organizing maps. Exposing threats and intrusions within packet payload at or near real-time rates enhances network security from both external and internal sources while ensuring security policy is rigorously applied to data and system resources. Intrusion Detection and Protection (IDP) is provided by a flow processing facility that processes a data flow to address patterns relevant to a variety of types of network and data integrity threats that relate to computer systems, including computer networks. | 10-23-2008 |
20120017262 | SYSTEMS AND METHODS FOR PROCESSING DATA FLOWS - A flow processing facility, which uses a set of artificial neurons for pattern recognition, such as a self-organizing map, in order to provide security and protection to a computer or computer system supports unified threat management based at least in part on patterns relevant to a variety of types of threats that relate to computer systems, including computer networks. Flow processing for switching, security, and other network applications, including a facility that processes a data flow to address patterns relevant to a variety of conditions are directed at internal network security, virtualization, and web connection security. A flow processing facility for inspecting payloads of network traffic packets detects security threats and intrusions across accessible layers of the IP-stack by applying content matching and behavioral anomaly detection techniques based on regular expression matching and self-organizing maps. Exposing threats and intrusions within packet payload at or near real-time rates enhances network security from both external and internal sources while ensuring security policy is rigorously applied to data and system resources. Intrusion Detection and Protection (IDP) is provided by a flow processing facility that processes a data flow to address patterns relevant to a variety of types of network and data integrity threats that relate to computer systems, including computer networks. | 01-19-2012 |
20120240185 | SYSTEMS AND METHODS FOR PROCESSING DATA FLOWS - A flow processing facility, which uses a set of artificial neurons for pattern recognition, such as a self-organizing map, in order to provide security and protection to a computer or computer system supports unified threat management based at least in part on patterns relevant to a variety of types of threats that relate to computer systems, including computer networks. Flow processing for switching, security, and other network applications, including a facility that processes a data flow to address patterns relevant to a variety of conditions are directed at internal network security, virtualization, and web connection security. A flow processing facility for inspecting payloads of network traffic packets detects security threats and intrusions across accessible layers of the IP-stack by applying content matching and behavioral anomaly detection techniques based on regular expression matching and self-organizing maps. Exposing threats and intrusions within packet payload at or near real-time rates enhances network security from both external and internal sources while ensuring security policy is rigorously applied to data and system resources. Intrusion Detection and Protection (IDP) is provided by a flow processing facility that processes a data flow to address patterns relevant to a variety of types of network and data integrity threats that relate to computer systems, including computer networks. | 09-20-2012 |
Patent application number | Description | Published |
20110152235 | Aminopyrimidine Kinase Inhibitors - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. | 06-23-2011 |
20120270892 | Aminopyrimidine Kinase Inhibitors - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. | 10-25-2012 |
20120316155 | Imidazole-2,4-Dione Inhibitors of Casein Kinase 1 - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), the TGFβ pathway and/or the Wnt pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), the TGFβ pathway and/or the Wnt pathway. | 12-13-2012 |
20130310342 | Aminopyrimidine Kinase Inhibitors - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of CK1, CK1γ1, CK1γ2, CK1γ3, CK2, Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of CK1, CK1γ1, CK1γ2, CK1γ3, CK2, Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway. | 11-21-2013 |
20140080799 | Aminopyrimidine Kinase Inhibitors - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. | 03-20-2014 |
Patent application number | Description | Published |
20100298331 | TRIAZINONE AND DIAZINONE DERIVATIVES USEFUL AS HSP90 INHIBITORS - The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound. | 11-25-2010 |
20110009397 | TRIAZONE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 01-13-2011 |
20110105749 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 05-05-2011 |
20120122869 | TRIZAOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 05-17-2012 |
20120330009 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 12-27-2012 |
20130225870 | METHOD OF SYNTHESIZING SUBSTITUTED 2-ALKYL PHENOLS - Methods of synthesizing 4-alkyl resorcinols and other substituted phenol compounds, according to formula (IV): or salts thereof, are disclosed, wherein the variables are defined herein. | 08-29-2013 |
20130345219 | TRIAZINONE AND DIAZINONE DERIVATIVES USEFUL AS HSP90 INHIBITORS - The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound. | 12-26-2013 |
Patent application number | Description | Published |
20110053368 | Arrangement for solder bump formation on wafers - An apparatus and a process for the manufacture of a solder-bump adhered wafer substrate for use in the semiconductor industry, comprising one or more of the following steps including: arranging a first compressive member and a second compressive member in an opposed, compressibly displaceable, spaced-apart relationship, with a pattern plate disposed therebetween with the pattern plate having a plurality of aligned through-holes arranged thereon; filling the through-holes with a molten solder; compressing the solder and the pattern plate between the first and second opposed compressive members to compact the solder therein and cleans the pattern plate of excess solder; chilling the pattern plate to solidify the molten solder in the through-holes; and removing the pattern plate from the spaced-apart compressive members to produce a wafer with solder bumps thereon. | 03-03-2011 |
20110215483 | Flux-free chip to substrate joint serial linear thermal processor arrangement - A linear, serial chip/substrate assembly processing machine for stepwise advancing a pre-assembled chip/die substrate on a support plate through a series of sealable chambers beginning at a loading station and ending up at an unloading station after various melting and vacuuming of chip/substrate components has been stepwise indexed through those various chambers to the final joining thereof. | 09-08-2011 |
20120289042 | Arrangement for solder bump formation on wafers - An apparatus and a process for the manufacture of a solder-bump adhered wafer substrate for use in the semiconductor industry, comprising one or more of the following steps including: arranging a first compressive member and a second compressive member in an opposed, compressibly displaceable, spaced-apart relationship, with a pattern plate disposed therebetween with the pattern plate having a plurality of aligned through-holes arranged thereon; filling the through-holes with a molten solder; compressing the solder and the pattern plate between the first and second opposed compressive members to compact the solder therein and cleans the pattern plate of excess solder; chilling the pattern plate to solidify the molten solder in the through-holes; and removing the pattern plate from the spaced-apart compressive members to produce a wafer with solder bumps thereon. | 11-15-2012 |
20130098700 | Foldable cart with tracking arrangement - A foldable cart assembly having a user tracking arrangement so as to follow movement of the user during motion over a field. The cart assembly has a plurality of ultrasound and RF sensors in communication with corresponding sensors in a remote handset transmission device carried by the user. The sensors provide timing, direction and distance information to a central processor on the cart for instructing individual electrical motors empowering the respective direction and speed of rotation of the cart's wheels. | 04-25-2013 |
20130103245 | Tracking foldable cart - A foldable cart assembly which is arranged to provide trackable transportation to a product or a person. The cart contains sensors and computer-controlled drive wheels to enable that cart assembly, when fully opened, to follow a safe path as directed by received electronic signals. That cart assembly is also tri-foldably collapsible, so as to have multiple portions pivoted into nesting configuration with one another thus containable in a minimal volume and even carried by an individual. | 04-25-2013 |
Patent application number | Description | Published |
20100125000 | GOLF CLUB HEAD OR OTHER BALL STRIKING DEVICE HAVING MULTI-PIECE CONSTRUCTION - A ball striking device has a head that includes a metal face configured for striking a ball, a rearwardly extending metal band, a top piece, and a bottom piece. The metal band has a first end extending from one side of the face, a second end extending from the opposite side of the face, and a rear portion extending between the first and second ends and defining at least a portion of the rear periphery of the head. The top piece and the bottom piece are non-metallic or substantially non-metallic. The top piece is connected to the top side of the metal band and forms at least a portion of a top side of the head, and the bottom piece is connected to the bottom side of the metal band and forms at least a portion of a bottom side of the head. The top piece and the bottom piece are separated by the metal band. | 05-20-2010 |
20100248852 | Golf Club Head and Head Cover Combination Providing Enhanced Functionality - A golf club head has structure for assisting a golfer, and a head cover has structure for supporting the golfer-assisting structure. In one aspect, the golfer-assisting structure provides a visual indicator, such as an alignment marker, a ball impact indicator, a temperature indicator, or the like. In another aspect, the golfer-assisting structure includes sensor(s) and/or other electronic components for measuring swing characteristics, course conditions, global position, or the like. The supporting structure may provide a source of energy, such as a power source, a light source, or a heat source. In some aspects, the supporting structure may include a processor for receiving data from the golfer-assisting structure, and may transmit data to a display on the head cover and/or to an external source. | 09-30-2010 |
20100261538 | Golf Club Having Hydrophobic And Hydrophilic Portions - A golf club or component thereof has a surface, wherein at least one area of the surface has a level of hydrophilicity which is less than the level of hydrophilicity in at least one surrounding portion, causing moisture to be preferentially attracted to the surrounding portion. In one aspect, the surface is a striking face and the surrounding portion is one or more grooves formed in the striking face. In another aspect, the surface is a grip and the surrounding portion is one or more channels formed in the grip. In some examples, hydrophobic or superhydrophobic surfaces on golf club components repel water and, in some instances, also offer self-cleaning functionality. | 10-14-2010 |
20110263350 | Golf Club Head or Other Ball Striking Device Having Multi-Piece Construction and Method for Manufacturing - A ball striking device has a head that includes a metal face configured for striking a ball, a rearwardly extending metal band, a top piece, and a bottom piece. The metal band has a first end extending from one side of the face, a second end extending from the opposite side of the face, and a rear portion extending between the first and second ends and defining at least a portion of the rear periphery of the head. The top piece and the bottom piece are non-metallic or substantially non-metallic. The top piece is connected to the top side of the metal band and forms at least a portion of a top side of the head, and the bottom piece is connected to the bottom side of the metal band and forms at least a portion of a bottom side of the head. The top piece and the bottom piece are separated by the metal band. | 10-27-2011 |
20120157225 | Golf Club Having Hydrophobic And Hydrophilic Portions - A golf club or component thereof has a surface, wherein at least one area of the surface has a level of hydrophilicity which is less than the level of hydrophilicity in at least one surrounding portion, causing moisture to be preferentially attracted to the surrounding portion. In one aspect, the surface is a striking face and the surrounding portion is one or more grooves formed in the striking face. In another aspect, the surface is a grip and the surrounding portion is one or more channels formed in the grip. In some examples, hydrophobic or superhydrophobic surfaces on golf club components repel water and, in some instances, also offer self-cleaning functionality. | 06-21-2012 |
20120157228 | Golf Club Having Hydrophobic And Hydrophilic Portions - A golf club or component thereof has a surface, wherein at least one area of the surface has a level of hydrophilicity which is less than the level of hydrophilicity in at least one surrounding portion, causing moisture to be preferentially attracted to the surrounding portion. In one aspect, the surface is a striking face and the surrounding portion is one or more grooves formed in the striking face. In another aspect, the surface is a grip and the surrounding portion is one or more channels formed in the grip. In some examples, hydrophobic or superhydrophobic surfaces on golf club components repel water and, in some instances, also offer self-cleaning functionality. | 06-21-2012 |
20130090181 | GOLF CLUB HEAD OR OTHER BALL STRIKING DEVICE WITH SLOTTED FACE MASK - A ball striking device, such as a golf club head, includes a head that includes a face having an outer surface located at a front of the head, a body connected to the face and extending rearward from the face, and a face mask connected to the outer surface of the face, the face mask having a first surface configured for forming at least a portion of a ball striking surface of the head configured for striking a ball, a second surface opposite the first surface and confronting the outer surface of the face, and a plurality of elongated slots extending completely through the face mask, from the first surface to the second surface. The slots combine with the outer surface of the face to form a plurality of face grooves on the ball striking surface. | 04-11-2013 |
20130165271 | Golf Ball Having Hydrophilic And Hydrophobic Portions - A golf having hydrophilic and hydrophobic portions is disclosed. In wet playing conditions, moisture may be repelled by the hydrophobic portions and attracted to the hydrophilic portions. Thus, the surface of the hydrophobic portions may remain dry such that the friction between a golf club head and the golf ball surface is not reduced. As a result, the golf ball may not be adversely affected by wet playing conditions. | 06-27-2013 |
20140130563 | AUTOMATED RAPID DISCHARGE FORMING OF METALLIC GLASSES - An automated rapid capacitive discharge apparatus is provided for sequentially or simultaneously rapidly heating and shaping a plurality of metallic glass feedstock samples. The apparatus includes a sample feeder defining a body for holding a plurality of samples and being capable of sequentially positioning at least one feedstock sample into a discharge position within the processing compartment. In the processing compartment the sample is heated by a discharge of a quantum of electrical energy supplied via electrodes, then shaped into a desired shape by means of a shaping tool, and subsequently moved out of the discharge position as a second feedstock moves into a discharge position. | 05-15-2014 |
20140202596 | MELT OVERHEATING METHOD FOR IMPROVED TOUGHNESS AND GLASS-FORMING ABILITY OF METALLIC GLASSES - A method of forming a bulk metallic glass is provided. The method includes overheating the alloy melt to a temperature above a threshold temperature, T | 07-24-2014 |
20140213384 | GOLF CLUB FABRICATED FROM BULK METALLIC GLASSES WITH HIGH TOUGHNESS AND HIGH STIFFNESS - Golf clubs formed from bulk-solidifying amorphous metals (i.e., metallic glasses) having high elastic modulus and fracture toughness, and to methods of forming the same are provided. Among other components, the golf club materials disclosed enable fabrication of flexural membranes or shells used in golf club heads (drivers, fairways, hybrids, irons, wedges and putters) exhibiting enhanced flexural or bending compliance together with the ability to deform plastically and avoid brittle fracture or catastrophic failure when overloaded under bending loads. Further, the high strength of the material and its density, comparable to that of steel, enables the redistribution of mass in the golf club while maintaining a desired overall target mass. | 07-31-2014 |
20140283956 | METHODS FOR SHAPING HIGH ASPECT RATIO ARTICLES FROM METALLIC GLASS ALLOYS USING RAPID CAPACITIVE DISCHARGE AND METALLIC GLASS FEEDSTOCK FOR USE IN SUCH METHODS - The disclosure is directed to a method of forming high-aspect-ratio metallic glass articles that are substantially free of defects and cosmetic flaws by means of rapid capacitive discharge forming. Metallic glass alloys that are stable against crystallization for at least 100 ms at temperatures where the viscosity is in the range of 10 | 09-25-2014 |
20150050181 | FLUXING METHOD TO REVERSE THE ADVERSE EFFECTS OF ALUMINUM IMPURITIES IN NICKEL-BASED GLASS-FORMING ALLOYS - A fluxing method is disclosed by which the melt of aluminum-contaminated Ni-based glass-forming alloys is fluxed using a fluxing agent based on boron and oxygen in order to reverse the adverse effects of aluminum impurities on the glass-forming ability and toughness. | 02-19-2015 |
Patent application number | Description | Published |
20110124869 | Process for Preparing Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 05-26-2011 |
20110251253 | SOLID FORMS OF (R)-1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6- -FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL) CYCLOPROPANECARBOXAMIDE - The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith. | 10-13-2011 |
20130072687 | Process for Preparing Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 03-21-2013 |
20130131107 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 05-23-2013 |
20130143918 | Solid Forms of (R)-1(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)-N-(1-(2,3-Dihydroxypropyl-6-F- luoro-2-(1-Hydroxy-2-Methylpropan-2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxa- mide - The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith. | 06-06-2013 |
20130143919 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 06-06-2013 |
20130158071 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 06-20-2013 |
Patent application number | Description | Published |
20080278358 | REFERENCE CIRCUITS FOR SAMPLED-DATA CIRCUITS - A switched capacitor circuit includes a first level-crossing detector to generate a level-crossing detection signal when an input signal crosses a first predetermined level. A first waveform generator generates a first predetermined waveform and a second waveform generator generates a second predetermined waveform. A second level-crossing detector generates a second level-crossing detection signal when said second predetermined waveform crosses a voltage reference level a second time. A second switch is coupled to the second level-crossing detector, and a third switch is coupled to the first level-crossing detector. The second switch turns OFF when the second level-crossing detection signal indicates the second predetermined waveform crossed the voltage reference level a second time. The third switch turns OFF when the first level-crossing detection signal indicates the input signal crossed the first predetermined level. | 11-13-2008 |
20090267650 | PASSIVE OFFSET AND OVERSHOOT CANCELLATION FOR SAMPLED-DATA CIRCUITS - A zero-crossing detector with effective offset cancellation includes a set of series connected capacitors and an amplifier having an input terminal. An offset capacitor is operatively connected between the amplifier and the set of series connected capacitors. A switch is operatively connected to the input terminal, and an offset sampling capacitor is operatively connected to the switch. The switch connects the offset sampling capacitor to the input terminal of the amplifier during a charge transfer phase. | 10-29-2009 |
20090309635 | CONSTANT SLOPE RAMP CIRCUITS FOR SAMPLED-DATA CIRCUITS - A circuit includes a level-crossing detector to generate a level-crossing detection signal when an input signal crosses a predetermined voltage level. A first stage set of capacitors is operatively coupled to the level-crossing detector. A ramp circuit is operatively coupled to the set of series-connected capacitors. A second stage set of capacitors is operatively coupled to the first stage set of capacitors and the ramp circuit. The ramp circuit includes a feedback capacitor and a preset switch to provide a linear ramp output. | 12-17-2009 |
20110032003 | OFFSET CANCELLATION FOR SAMPLED-DATA CITCUITS - A comparator based circuit with effective offset cancellation includes first and second amplifiers and an offset capacitor operatively connected to the first and second amplifiers. An offset voltage source generates an offset voltage. A first switch connects the offset voltage source to ground during a first time period. The first amplifier generates an output voltage in response to the first switch connecting the offset voltage source to ground during the first time period. A second switch connects the offset capacitor to ground during a second time period. The first switch disconnects the offset voltage source from ground during a third time period, and the second switch disconnects the offset capacitor from ground during the third time period. | 02-10-2011 |
20130127516 | Offset Cancellation for Sampled-Data Circuits - A comparator based circuit with effective offset cancellation includes first and second amplifiers and an offset capacitor operatively connected to the first and second amplifiers. An offset voltage source generates an offset voltage. A first switch connects the offset voltage source to ground during a first time period. The first amplifier generates an output voltage in response to the first switch connecting the offset voltage source to ground during the first time period. A second switch connects the offset capacitor to ground during a second time period. The first switch disconnects the offset voltage source from ground during a third time period, and the second switch disconnects the offset capacitor from ground during the third time period | 05-23-2013 |
20130285469 | CONSTANT SLOPE RAMP CIRCUITS FOR SAMPLED-DATA CIRCUITS - A circuit includes a level-crossing detector to generate a level-crossing detection signal when an input signal crosses a predetermined voltage level. A first stage set of capacitors is operatively coupled to the level-crossing detector. A ramp circuit is operatively coupled to the set of series-connected capacitors. A second stage set of capacitors is operatively coupled to the first stage set of capacitors and the ramp circuit. The ramp circuit includes a feedback capacitor and a preset switch to provide a linear ramp output. | 10-31-2013 |
Patent application number | Description | Published |
20110269739 | KINASE INHIBITORS - The present invention provides a new group of protein kinase inhibitors, pyrido[4,3,-d]pyrimidin-5-one derivatives, and pharmaceutically acceptable salts thereof that are useful for intreating cell proliferative disease and disorder such as cancer, autoimmune diseases, infection, cardiovascular disease and neurodegenerative disease and disorder. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. The invention also provides useful intermediates generated during the syntheses of the pyrido[4,3,-d]pyrimidin-5-one derivatives. | 11-03-2011 |
20110281841 | Kinase Inhibitors - The present invention provides a new group of protein kinase inhibitors, pyrropyrimidine and pyrazolopyrimidine derivatives, and pharmaceutically acceptable salts and prodrugs thereof that are useful for treating cell proliferative disease and disorder such as cancer, autoimmune diseases, infection, cardiovascular disease and neurodegenerative disease and disorder. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. The invention also provides useful intermediates generated during the syntheses of the pyrropyrimidine and pyrazolopyrimidine derivatives. | 11-17-2011 |
20130274242 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE AS SYK INHIBITORS - Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I). | 10-17-2013 |
20130274274 | SUBSTITUTED PYRIDOPYRIMIDINE COMPOUNDS AND THEIR USE AS FLT3 INHIBITORS - Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I). | 10-17-2013 |
Patent application number | Description | Published |
20090240462 | System and Method for Capturing an Event in MEMS Inertial Sensors - A method of capturing an event in a MEMS accelerometer stores acceleration data in memory, detects a trigger event based on the acceleration data, and modifies a configuration of the memory so that a specified amount of the acceleration data is saved. A MEMS event capturing system includes an inertial sensor having sensor circuitry and event capturing circuitry implemented with the sensor circuitry. The event capturing circuitry includes memory capable of storing acceleration data received from the inertial sensor and a detection module operatively coupled with the memory that detects a trigger event. The event capturing circuitry also includes a management module operatively coupled with the memory and the detection module that modifies the memory's storage configuration when the trigger event is detected. | 09-24-2009 |
20090240463 | Activity Detection in MEMS Accelerometers - A method of detecting activity in a MEMS accelerometer captures an acceleration bias, measures acceleration at a predetermined time, calculates a change in acceleration using the measured acceleration and the acceleration bias, and compares the change in acceleration to a threshold to detect activity. A method of detecting inactivity uses a similar technique along with a timer. The method of detecting inactivity in a MEMS accelerometer captures an acceleration bias, measures acceleration at a predetermined time, calculates a change in acceleration using the measured acceleration and the acceleration bias, and compares the change in acceleration to a threshold to detect inactivity. The method further determines if the change in acceleration is less than the threshold and, if so, determines if a predetermined period of time has elapsed to detect inactivity. | 09-24-2009 |
20090293615 | Management System for MEMS Inertial Sensors - A MEMS system includes an inertial sensor having sensor circuitry and management circuitry implemented with the sensor circuitry. The management circuitry includes a detection module that detects a condition of the system and a management module that coordinates the functionality of the inertial sensor and the detection module based on the detected condition. | 12-03-2009 |
20110087454 | Tap Detection - Methodology and circuitry for determining if a device, such as a cellular phone or personal digital assistant has been tapped is disclosed. The device includes an accelerometer and in response to an acceleration, the accelerometer outputs an acceleration signal. The accelerometer may continuously output an acceleration signal even if no acceleration occurs. A tap detection device receives the temporally sampled acceleration signal and takes the first derivative of the temporally sampled acceleration signal producing one or more derivative values. The tap detection system compares each derivative value to a threshold value and if the derivative value exceeds the threshold a tap is detected. By taking the derivative of the acceleration signal, the noise floor for the acceleration signal is reduced leading to more accurate results with less false positives and less positive negatives. | 04-14-2011 |
20120092916 | Built-In Self Test for One-Time-Programmable Memory - An apparatus and method of testing one-time-programmable memory provides one-time-programmable memory having one or more memory locations for storing data and corresponding programming circuitry for each memory location. In addition, each programming circuitry has a circuit element configured to permanently change state to store the data in the memory. The method also reads each memory location to verify that the memory location is unprogrammed and activates the programming circuitry for each memory location, which applies a test current to the programming circuitry. The test current is less than a threshold current needed to permanently change the state of the circuit element. The method then determines whether the programming circuitry is functioning properly. | 04-19-2012 |
20120279304 | Activity Detection in MEMS Accelerometers - A method of detecting activity with a MEMS accelerometer stores a value of acceleration, then measures acceleration at a later time, calculates a change in acceleration using the measured acceleration and the stored acceleration, and compares the change in acceleration to an activity threshold to detect activity. A method of detecting inactivity uses a similar technique along with a timer. The method of detecting inactivity with a MEMS accelerometer stores an acceleration value, then measures acceleration at a later time, calculates a change in acceleration using the measured acceleration and the stored acceleration, and compares the change in acceleration to an inactivity threshold. If the change in acceleration is less than the inactivity threshold and, if a predetermined period of time has elapsed, then inactivity is detected. | 11-08-2012 |
20130294143 | Built-In Self Test for One-Time-Programmable Memory - An apparatus and method of testing one-time-programmable memory provides one-time-programmable memory having one or more memory locations for storing data and corresponding programming circuitry for each memory location. In addition, each programming circuitry has a circuit element configured to permanently change state to store the data in the memory. The method also reads each memory location to verify that the memory location is unprogrammed and activates the programming circuitry for each memory location, which applies a test current to the programming circuitry. The test current is less than a threshold current needed to permanently change the state of the circuit element. The method then determines whether the programming circuitry is functioning properly. | 11-07-2013 |
20140056452 | Portable Device with Power Management Controls - A wearable device has a motion detector configured to detect motion of the device and produce a motion signal relating to motion of the device, a contact sensor configured to detect if the device is in contact with an object and produce a contact signal relating to whether the device is in contact with an object, and a controller operatively coupled with the motion detector and the contact sensor. The controller is configured to switch between on and off-states as a function of at least one of the motion signal and contact signal. The device also has a sound transducer or other transducer operatively coupled with the controller. The controller is configured to change the state of the sound transducer between on and off-states in response to receipt of the motion signal, and the contact signal. | 02-27-2014 |
20140250969 | Spread-Spectrum MEMS Self-Test System and Method - A MEMS sensor includes a micro-electromechanical structure, a detection circuit, and a self-test circuit to test the health of the MEMS sensor during runtime operations. The self-test circuit is configured to inject into the micro-electromechanical structure a plurality of injected test signals that are broad-band frequency-varying frequency signals, which are based on spread spectrum based modulation. The injected test signals may a magnitude that is below an observable threshold of the sensor signal as well as a test-signal bandwidth that overlaps with a substantial portion of the sensor bandwidth, including the stimulus of interest. | 09-11-2014 |
Patent application number | Description | Published |
20080239920 | Wireless transmission of temperature data - An identification input device and a temperature detector that detects body temperature data. The identification input device may be an optical touch pen. The infrared touch pen may be affixed to the temperature detector using a hook and connector or a snap fit connector. In use, the temperature detector computes body temperature data and the identification input device determines an identifier. The identifier is unique to a user. After obtaining the body temperature data and identifier, a transmitter may transmit body temperature data and the identifier over a wireless communications path to a processing unit. By transmitting data over a wireless communications path, an individual's data or a large group of data may be analyzed and viewed via a display unit. | 10-02-2008 |
20080262782 | Wireless transmission of temperature data for a geographic area - A user obtains an individual's body temperature data and transmits the data to a medical monitor (e.g., a medical device) for display. Additional data includes a timestamp and location of the body temperature data. Once the data is transmitted, a user may view the medical monitor for a temperature reading. For example, a doctor may take a patient's temperature and the temperature reading is displayed on a medical monitor. The body temperature data of each patient is detected using a preferred temperature detector, such as a temporal artery thermometer using an arterial heat balance approach. After collecting an individual's body temperature data, the body temperature data can be transferred to a processor. By sending body temperature data for many individuals for a geographic region, the processor can identify a pattern (e.g., a pandemic) in the body temperature data. | 10-23-2008 |
20120197585 | Wireless Transmission of Temperature Data for a Geographic Area - A user obtains an individual's body temperature data and transmits the data to a medical monitor (e.g., a medical device) for display. Additional data includes a timestamp and location of the body temperature data. Once the data is transmitted, a user may view the medical monitor for a temperature reading. For example, a doctor may take a patient's temperature and the temperature reading is displayed on a medical monitor. The body temperature data of each patient is detected using a preferred temperature detector, such as a temporal artery thermometer using an arterial heat balance approach. After collecting an individual's body temperature data, the body temperature data can be transferred to a processor. By sending body temperature data for many individuals for a geographic region, the processor can identify a pattern (e.g., a pandemic) in the body temperature data. | 08-02-2012 |
20140046620 | Wireless Transmission Of Temperature Data For A Geographic Area - A user obtains an individual's body temperature data and transmits the data to a medical monitor (e.g., a medical device) for display. Additional data includes a timestamp and location of the body temperature data. Once the data is transmitted, a user may view the medical monitor for a temperature reading. For example, a doctor may take a patient's temperature and the temperature reading is displayed on a medical monitor. The body temperature data of each patient is detected using a preferred temperature detector, such as a temporal artery thermometer using an arterial heat balance approach. After collecting an individual's body temperature data, the body temperature data can be transferred to a processor. By sending body temperature data for many individuals for a geographic region, the processor can identify a pattern (e.g., a pandemic) in the body temperature data. | 02-13-2014 |
20140149065 | METHOD AND APPARATUS FOR ACCURATE DETECTION OF FEVER - The present invention relates to more accurate indication of fever. Temperature data from a large population of individuals are obtained and the temperature data are processed to determine a threshold, at a fever bump, above a normal range of distribution. The fever threshold, along with an individual's temperature, is used to indicate if the individual has a fever. Further, circadian information may be utilized to adjust the temperature data for an individual or the population of individuals. | 05-29-2014 |
20140243700 | WIRELESS TRANSMISSION OF TEMPERATURE DATA - An identification input device and a temperature detector that detects body temperature data. The identification input device may be an optical touch pen. The infrared touch pen may be affixed to the temperature detector using a hook and connector or a snap fit connector. In use, the temperature detector computes body temperature data and the identification input device determines an identifier. The identifier is unique to a user. After obtaining the body temperature data and identifier, a transmitter may transmit body temperature data and the identifier over a wireless communications path to a processing unit. By transmitting data over a wireless communications path, an individual's data or a large group of data may be analyzed and viewed via a display unit. | 08-28-2014 |
Patent application number | Description | Published |
20100160472 | POLYOLEFIN AEROGELS AND COMPOSITES - The present invention relates to cross-linked polyolefin aerogels in simple and fiber-reinforced composite form. Of particular interest are polybutadiene aerogels. Especially aerogels derived from polybutadienes functionalized with anhydrides, amines, hydroxyls, thiols, epoxies, isocyanates or combinations thereof. | 06-24-2010 |
20140080932 | MICROPOROUS POLYOLEFIN-BASED AEROGELS - Microporous polyolefin and microporous polydicyclopentadiene (polyDCPD) based aerogels and methods for preparing and using the same are provided. The aerogels are produced by forming a polymer gel structure within a solvent from a olefin or dicyclopentadiene monomer 5 via Ring Opening Metathesis Polymerization (ROMP) reactions, followed by supercritical drying to remove the solvent from the aerogel. Other aerogels are prepared by sequentially (1) mixing at least one dicyclopentadiene monomer, at least one solvent at least one catalyst and at least one inorganic and/or organic reinforcing material, (2) gelling the mixture, (3) aging, and (4) supercritical drying. Aerogels provided herein are inexpensive to prepare, possess desirable 10 thermal, mechanical, acoustic, chemical, and physical properties and are hydrophobic. The aerogels provided herein are suitable for use in various applications, including but not limited to thermal and acoustic insulation, radiation shielding, and vibrational damping applications. | 03-20-2014 |
Patent application number | Description | Published |
20080221077 | Ansamycin formulations and methods of use thereof - Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”). | 09-11-2008 |
20090062528 | Ansamycin formulations and methods of use thereof - Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”). | 03-05-2009 |
20090069281 | Ansamycin formulations and methods of use thereof - Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”). | 03-12-2009 |
Patent application number | Description | Published |
20090293276 | ROTOR ASSEMBLY SYSTEM AND METHOD - A method and system are disclosed for use in assembling a plurality of rotatable elements in the assembly of a turbine engine. The system and method include an initialization unit, a measurement unit, and a processing unit. The initialization unit receives and stores initialization data in a computer datastore. The initialization data includes a first set of initialization data that is representative of characteristics of a first rotatable element, and a second set of initialization data that is representative of characteristics of a second rotatable element. The measurement unit receives measured data including a first set of measured data characteristic of measured features of the first rotatable element, and a second set of measured data characteristic of measured features of the second rotatable element. The processor unit determines an optimal order and rotational arrangement of the first and second rotatable elements with respect to one another responsive to the first and second sets of initialization data and the first and second sets of measured data. | 12-03-2009 |
20090320309 | SYSTEM FOR OPTIMAL ALIGNMENT OF A BEARING SEAL ON A SHAFT OF A GAS TURBINE - A method for substantially aligning a bearing seal on a shaft of a turbine engine. The method including measuring characteristics of the subject shaft, measuring characteristics of a plurality of bearing seal components and determining and outputting alignment information of the plurality of bearing seal components with the shaft based on the measured characteristics. The alignment information can be outputted for either substantially perpendicular alignment for an axial seal or substantially parallel alignment for a radial seal. | 12-31-2009 |
20100198553 | ABSOLUTE DIAMETER MEASUREMENT ARM - A measurement apparatus calibrated to measure an absolute diameter of a part in a shop floor environment. The measurement apparatus includes a calibration that includes compensation factors for thermal expansion, shifting of measurement parts (arm, support tower, and related laser), and variances of these parts. The resulting measurements report an absolute diameter of a part to a higher degree of accuracy than previously possible. Also, the calculated compensation factor eliminate the need for an isolated, climate-controlled measurement room. | 08-05-2010 |
20120310595 | ABSOLUTE DIAMETER MEASUREMENT ARM - A measurement apparatus calibrated to measure an absolute diameter of a part in a shop floor environment. The measurement apparatus includes a calibration that includes compensation factors for thermal expansion, shifting of measurement parts (arm, support tower, and related laser), and variances of these parts. The resulting measurements report an absolute diameter of a part to a higher degree of accuracy than previously possible. Also, the calculated compensation factor eliminate the need for an isolated, climate-controlled measurement room. | 12-06-2012 |
20140096405 | ABSOLUTE DIAMETER MEASUREMENT ARM - A measurement apparatus and corresponding method can be used to measure an absolute diameter of a part in a shop floor environment. A tracker such as a laser tracker monitors a position of a probe end of a measurement arm of the apparatus. The position measured by the laser tracker can be used directly account for errors in the apparatus such as, for example, positioning errors of the measurement arm. The position monitoring of the tracking device eliminates complex apparatus calibrations and calculations used for previous devices. | 04-10-2014 |
Patent application number | Description | Published |
20090061221 | COMPOSITE TACK FILM FOR ASPHALTIC PAVING, METHOD OF PAVING, AND PROCESS FOR MAKING A COMPOSITE TACK FILM FOR ASPHALTIC PAVING - A tack film material comprises a carrier substrate comprising a polymer film having first and second major surfaces. A surface layer on the first and second major surfaces comprises a resinous non-asphaltic material or a material including about 50% or more resinous non-asphaltic component and about 50% or less of asphaltic component. The surface layer is capable of forming a bond with an adjacent layer of asphaltic paving material, when the surface layer is heated to a temperature of about 120° C. or more under a pressure that is applied to the tack film material by an overlying layer of the asphaltic paving material having a thickness of about 3.8 cm (1.5 inch) or more laid. The surface layer is not tacky at a temperature of about 20° C. and a pressure of about one atmosphere. | 03-05-2009 |
20090097917 | REINFORCEMENT FOR ASPHALTIC PAVING, METHOD OF PAVING, AND PROCESS FOR MAKING A GRID WITH THE COATING FOR ASPHALTIC PAVING - A composite material comprises: an open grid comprising at least two sets of strands. Each set of strands has openings between adjacent strands. The sets are oriented at a substantial angle to one another. A tack film is laminated to the open grid. The tack film has first and second major surfaces, such that a material of the tack film at its first and second major surfaces is a material including about 50% or more of resinous non-asphaltic component and about 50% or less of asphaltic component. | 04-16-2009 |
20090098330 | COMPOSITE GRID WITH TACK FILM FOR ASPHALTIC PAVING, METHOD OF PAVING, AND PROCESS FOR MAKING A COMPOSITE GRID WITH TACK FILM FOR ASPHALTIC PAVING - A composite material comprises: an open grid comprising at least two sets of strands. Each set of strands has openings between adjacent strands. The sets are oriented at a substantial angle to one another. A tack film is laminated to the open grid. The tack film has first and second major surfaces, such that a material of the tack film at its first and second major surfaces includes about 50% or more of resinous non-asphaltic component and about 50% or less of asphaltic component. | 04-16-2009 |
20120003889 | REINFORCEMENT FOR ASPHALTIC PAVING, METHOD OF PAVING, AND PROCESS FOR MAKING A GRID WITH THE COATING FOR ASPHALTIC PAVING - A composite material comprises: an open grid comprising at least two sets of strands. Each set of strands has openings between adjacent strands. The sets are oriented at a substantial angle to one another. A tack film is laminated to the open grid. The tack film has first and second major surfaces, such that a material of the tack film at its first and second major surfaces is a material including about 50% or more of resinous non-asphaltic component and about 50% or less of asphaltic component. | 01-05-2012 |
Patent application number | Description | Published |
20110230521 | Pyrazole Compounds As CCR1 Antagonists - Disclosed are compounds of the formula (I) which block the interaction of CCR1 and its ligands and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes. | 09-22-2011 |
20120184516 | sGC Stimulators - Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. | 07-19-2012 |
20130178475 | sGC STIMULATORS - Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. | 07-11-2013 |
20140088071 | sGC STIMULATORS - Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. | 03-27-2014 |
20140323448 | sGC STIMULATORS - Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed. | 10-30-2014 |
Patent application number | Description | Published |
20100110603 | WAFER GROUNDING METHOD FOR ELECTROSTATIC CLAMPS - An electrostatic chuck and method for clamping and de-clamping a workpiece is provided. The ESC comprises a clamping plate having a clamping surface, and one or more electrodes. An electric potential applied to the one or more electrodes selectively clamps the workpiece to the clamping surface. An arc pin operably coupled to the clamping plate and a power source provides an arc for penetrating an insulating layer of the workpiece. The arc pin is selectively connected to an electrical ground, wherein upon removal of the insulative layer of the workpiece, the arc pin provides an electrical ground connection to the workpiece. | 05-06-2010 |
20100110604 | ELECTROSTATIC CHUCK GROUND PUNCH - An electrostatic chuck and method for clamping a workpiece is provided. The ESC comprises a clamping plate having a clamping surface, and one or more electrodes. An electric potential applied to the one or more electrodes selectively clamps the workpiece to the clamping surface. A punch is operably coupled to the clamping plate and an electrical ground, wherein the punch comprises a trigger mechanism and a punch tip. The punch tip translates between extended and retracted positions, wherein a point of the punch tip is proud of the clamping surface when the punch tip is in the extended position. The punch tip is configured to translate toward the clamping surface upon clamping the workpiece to the clamping plate. Upon reaching the retracted position, the trigger mechanism imparts an impact force to the punch tip, forcing the punch tip into the workpiece and providing an electrical ground connection to the workpiece. | 05-06-2010 |
20100142113 | DE-CLAMPING WAFERS FROM AN ELECTROSTATIC CHUCK - One embodiment of the present invention relates to a method for declamping a semiconductor wafer that is electrically adhered to a surface of an electrostatic chuck by a clamping voltage. In this method, the clamping voltage is deactivated. For a time following the deactivation, a first region of the wafer is lifted an first distance from the surface of the electrostatic chuck while a second region of the wafer remains adhered to the surface of the electrostatic chuck. A predetermined condition is monitored during the time. The second region is lifted from the surface of the electrostatic chuck when the predetermined condition is met. | 06-10-2010 |
20100142114 | ELECTROSTATIC CHUCK WITH COMPLIANT COAT - The present invention is directed to an electrostatic chuck (ESC) with a compliant layer formed from TT-Kote® and a method of forming a clamping plate for an ESC. The ESC comprises a compliant layer having a low friction surface for reducing or eliminating particulates generated from thermal expansion. The method comprises forming a clamping member for a substrate comprising a ceramic material and a ceramic surface, and coating the ceramic surface with a compliant layer comprising an organic silicide or TT-Kote®. | 06-10-2010 |
20100171044 | Vapor Compression Refridgeration Chuck for Ion Implanters - Aspects of the present invention relate to ion implantation systems that make use of a vapor compression cooling system. In one embodiment, a thermal controller in the vapor compression system sends refrigeration fluid though a compressor and a condenser according to an ideal vapor compression cycle to help limit or prevent undesired heating of a workpiece during implantation, or to actively cool the workpiece. | 07-08-2010 |
20100187447 | NON-CONDENSING THERMOS CHUCK - The present invention is directed to an apparatus and method of forming a thermos layer surrounding a chuck for holding a wafer during ion implantation. The thermos layer is located below a clamping surface, and comprises a vacuum gap and an outer casing encapsulating the vacuum gap. The thermos layer provides a barrier blocking condensation to the outside of the chuck within a process chamber by substantially preventing heat transfer between the chuck when it is cooled and the warmer environment within the process chamber. | 07-29-2010 |
20110291022 | Post Implant Wafer Heating Using Light - An ion implantation system, method, and apparatus for abating condensation in a cold ion implant is provided. An ion implantation apparatus is configured to provide ions to a workpiece positioned in a process chamber. A sub-ambient temperature chuck supports the workpiece during an exposure of the workpiece to the plurality of ions. The sub-ambient temperature chuck is further configured to cool the workpiece to a processing temperature, wherein the process temperature is below a dew point of an external environment. A load lock chamber isolates a process environment of the process chamber from the external environment. A light source provides a predetermined wavelength of electromagnetic radiation to the workpiece concurrent with the workpiece residing within the load lock chamber, wherein the predetermined wavelength or range of wavelengths is associated with a maximum radiant energy absorption range of the workpiece, wherein the light source is configured to selectively heat the workpiece. | 12-01-2011 |
20110291023 | HEATED ROTARY SEAL AND BEARING FOR CHILLED ION IMPLANTATION SYSTEM - A workpiece scanning system is provided having a scan arm that rotates about a first axis and a chilled end effector rotatably coupled to the scan arm about a second axis for selectively securing a workpiece. The chilled end effector has a clamping plate and one or more cooling mechanisms for cooling the clamping plate. A bearing is positioned along the second axis and rotatably couples the end effector to the scan arm, and a seal is positioned along the second axis to provide a pressure barrier between an external environment and an internal environment. One or more of the bearing and seal can have a ferrofluid associated therewith. A heater assembly is positioned proximate to the bearing and seal, wherein the heater assembly selectively provides a predetermined amount of heat to the bearing and seal, therein increasing a propensity of the end effector to rotate about the second axis. | 12-01-2011 |
20110291030 | ACTIVE DEW POINT SENSING AND LOAD LOCK VENTING TO PREVENT CONDENSATION ON WORKPIECES - A system, apparatus, and method is provided for preventing condensation on a workpiece in an end station of an ion implantation system. A workpiece is cooled in a first environment, and is transferred to a load lock chamber that is in selective fluid communication with the end station and a second environment, respectively. A workpiece temperature monitoring device is configured to measure a temperature of the workpiece in the load lock chamber. An external monitoring device measures a temperature and relative humidity in the second environment, and a controller is configured to determine a temperature of the workpiece at which condensation will not form on the workpiece when the workpiece is transferred from the load lock chamber to the second environment. | 12-01-2011 |
20110292562 | MATCHED COEFFICIENT OF THERMAL EXPANSION FOR AN ELECTROSTATIC CHUCK - An apparatus and method are provided for selecting materials for forming an electrostatic clamp. The electrostatic clamp has a backing plate having a first coefficient of thermal expansion, wherein the backing plate provides structural support and rigidity to the electrostatic clamp. The electrostatic clamp further has a clamping plate having a clamping surface associated with contact with a workpiece, wherein the clamping plate has a second coefficient of thermal expansion associated therewith. The clamping plate is bonded, attached or grown to the backing plate, wherein minimal deflection of the clamping plate is evident across a predetermined temperature range. The first coefficient of thermal expansion and second coefficient of thermal expansion, for example, are substantially similar, and vary by no greater than a factor of three. | 12-01-2011 |
20120190181 | CARBON IMPLANTATION PROCESS AND CARBON ION PRECURSOR COMPOSITION - Methods and carbon ion precursor compositions for implanting carbon ions generally includes vaporizing and ionizing a gas mixture including carbon oxide and methane gases in an ion source to create a plasma and produce carbon ions. The ionized carbon within the plasma is then extracted to form an ion beam. The ion beam is mass analyzed with a mass analyzer magnet to permit the ionized carbon to pass therethrough and implant into a workpiece. | 07-26-2012 |
20120267546 | Vacuum System Cold Trap Filter - A cold trap filter and method is provided for filtering chemical species from a vacuum system of an ion implantation system. A canister is in fluid communication with an exhaust of a high vacuum pump and an intake of a roughing pump used for evacuating an ion source chamber. One or more paddles are positioned within the canister, wherein each paddle has a cooling line in fluid communication with a coolant source. The coolant source passes a coolant through the cooling line, thus cooling the one or more paddles to a predetermined temperature associated with a condensation or deposition point of the chemical species, therein condensing or depositing the chemical species on the paddles while not interfering with a vacuum capacity of the high vacuum and roughing pumps. The paddles can also be electrically biased to electrostatically attract the chemical species to the paddles in one or more biasing steps. | 10-25-2012 |
20130305988 | Inline Capacitive Ignition of Inductively Coupled Plasma Ion Source - An ion source is disclosed that utilizes a capacitive discharge to produce ignition ions, which are subsequently used to ignite an inductively coupled plasma within a plasma chamber. In some embodiments, a capacitive discharge element is located along a gas feed line at a position that is upstream of a plasma chamber. The capacitive discharge element ignites a capacitive discharge within the gas feed line. The capacitive discharge contains ignition ions that are provided to a downstream plasma chamber. An inductively coupled plasma ignition element, in communication with the plasma chamber, ignites and sustains a high density inductively coupled plasma within the plasma chamber based upon ignition ions from the capacitive discharge. Due to the ignition ions, the inductively coupled plasma element can easily ignite the high density inductively coupled plasma, even at a low pressure. | 11-21-2013 |
20130320208 | Inert Atmospheric Pressure Pre-Chill and Post-Heat - An ion implantation system provides ions to a workpiece positioned in a process environment of a process chamber on a sub-ambient temperature chuck. An intermediate chamber having an intermediate environment is in fluid communication with an external environment and has a cooling station and heating station for cooling and heating the workpiece. A load lock chamber is provided between the process chamber and intermediate chamber to isolate the process environment from the intermediate environment. A positive pressure source provides a dry gas within the intermediate chamber at dew point that is less than a dew point of the external environment to the intermediate chamber. The positive pressure source isolates the intermediate environment from the external environment via a flow of the dry gas from the intermediate chamber to the external environment. | 12-05-2013 |
20140034846 | IN-VACUUM HIGH SPEED PRE-CHILL AND POST-HEAT STATIONS - An ion implantation system provides ions to a workpiece positioned in a vacuum environment of a process chamber on a cooled chuck. A pre-chill station within the process chamber has a chilled workpiece support configured to cool the workpiece to a first temperature, and a post-heat station within the process chamber, has a heated workpiece support configured to heat the workpiece to a second temperature. The first temperature is lower than a process temperature, and the second temperature is greater than an external temperature. A workpiece transfer arm is further configured to concurrently transfer two or more workpieces between two or more of the chuck, a load lock chamber, the pre-chill station, and the post-heat station. | 02-06-2014 |
Patent application number | Description | Published |
20110260047 | SILABORANE IMPLANTATION PROCESSES - Methods for implanting an silaborane molecule or a selected ionized lower mass byproduct into a workpiece generally includes vaporizing and ionizing silaborane molecule in an ion source to create a plasma and produce silaborane molecules and its ionized lower mass byproducts. The ionized silaborane molecules and lower mass byproducts within the plasma are then extracted to form an ion beam. The ion beam is mass analyzed with a mass analyzer magnet to permit selected ionized silaborane molecules or selected ionized lower mass byproducts to pass therethrough and implant into a workpiece. | 10-27-2011 |
20110297845 | EFFECTIVE ALGORITHM FOR WARMING A TWIST AXIS FOR COLD ION IMPLANTATIONS - A method for warming a rotational interface in an ion implantation environment provides a scan arm configured to rotate about a first axis and an end effector coupled to the scan arm via a motor to selectively secure a workpiece. The end effector is configured to rotate about a second axis having a bearing and a seal associated with the second axis and motor. The motor is activated, and the rotation of motor is reversed after a predetermined time or when the motor faults due to a rotation the end effector about the second axis. A determination is made as to whether the rotation of the end effector about the second axis is acceptable, and the scan arm is reciprocated about the first axis when the rotation of the end effector is unacceptable, wherein inertia of the end effector causes a rotation of the end effector about the second axis. | 12-08-2011 |
20110299217 | HEATED ELECTROSTATIC CHUCK INCLUDING MECHANICAL CLAMP CAPABILITY AT HIGH TEMPERATURE - An electrostatic clamp is provided, having a clamping plate, wherein a clamping surface of the clamping plate is configured to contact the workpiece. A voltage applied to one or more electrodes selectively electrostatically attracts the workpiece to the clamping surface. One or more auxiliary clamping members are further provided wherein the one or more auxiliary clamping members are configured to selectively secure at least a portion of the workpiece to the clamping surface. A temperature monitoring device configured to determine a temperature of the workpiece is provided, and a controller is configured to selectively clamp the workpiece to the clamping surface via a control of the voltage to the one or more electrodes and the one or more auxiliary clamping members, based, at least in part, on the temperature of the workpiece. | 12-08-2011 |
20110299218 | HEATED ANNULUS CHUCK - A clamping device and method is provided for securing first and second workpieces having different sizes to a clamping device and providing thermal conditioning thereto. An electrostatic clamping plate having a diameter associated with the first workpiece surrounds a central portion of the clamp. A non-electrostatic central portion provides a heater within the annulus, wherein the central portion has a diameter associated with the second workpiece. A workpiece carrier is provided, wherein the workpiece carrier is configured to hold the second workpiece above the heater, and wherein a diameter of the workpiece carrier is associated with the electrostatic clamping plate annulus. The annulus selectively electrostatically clamps the workpiece carrier or a circumferential portion of the first workpiece to its clamping surface, therein selectively maintaining a position of the first or second workpiece with respect to the annulus or non-electrostatic central portion. | 12-08-2011 |
20130118304 | High Temperature Reactor System and Method for Producing a Product Therein - A plasma system including a plasma source or torch such as an ICP torch acting on a granulated feed material containing a desired product is presented. Methods for employing the system are described including a process for extracting the desired product from a reaction in the plasma system, recovery of otherwise wasted heat energy, and separation of useful materials from mixed mineral substances is discussed. | 05-16-2013 |
20130118305 | Magneto-Plasma Separator and Method for Separation - A plasma separator and mass filter system is described. In some aspects the system is designed and configured to cause a plasma in a vacuum chamber and to move charged particles therein axially and circumferentially towards one or more sets of collectors. Waste material is ejected from the system while the one or more collectors yield one or more corresponding products. | 05-16-2013 |
20140188416 | CHARGE INTEGRATION BASED ELECTROSTATIC CLAMP HEALTH MONITOR - An electrostatic clamp monitoring system is provided having an electrostatic clamp configured to selectively electrostatically clamp a workpiece to a clamping surface associated therewith via one or more electrodes. A power supply is electrically coupled to the electrostatic clamp, wherein the power supply is configured to selectively supply a clamping voltage to the one or more electrodes of the electrostatic clamp. A data acquisition system is coupled to the power supply and configured to measure a current supplied to the one or more electrodes, therein defining a measured current. A controller integrates the measured current over time, therein determining a charge value associated a clamping force between the workpiece and electrostatic clamp. A memory stores the charge value associated with the clamping force over a plurality of clamping cycles, therein defining a plurality of charge values, and the controller determines a clamping capability of the electrostatic clamp based on a comparison of a currently determined charge value to the plurality of charge values. | 07-03-2014 |
20140361197 | WORKPIECE CARRIER - A workpiece carrier comprises a first plate having a first outer diameter, a first inner diameter, and a first recess extending a first distance from the first inner diameter toward the first outer diameter. The workpiece carrier further comprises a second plate having a second outer diameter, a second inner diameter, and a second recess extending a second distance from the second inner diameter toward the second outer diameter. A plurality of mating features associated with the first plate and second plate are configured to selectively fix a position of a first workpiece between the first plate and second plate within the first recess and second recess. | 12-11-2014 |
Patent application number | Description | Published |
20110113026 | Scalable Computation of Data - Techniques for producing a cross tabulation are described. The techniques involve issuing a plurality of queries to a database. The queries are for each of at least one sublevel of data for each of at least one dimension of data associated with records in the database. The queries provide sublists of sorted identifiers for each one of the queries. The technique determines occurrences of intersections of levels of one dimension with levels of another dimension of the data associated with records in the database by traversing the sublists to detect intersections of the dimensions. | 05-12-2011 |
20130346184 | CONTACT HISTORY FOR PROMOTION MANAGEMENT - A computer implemented method for producing a contact history for a marketing campaign is described. The method includes producing a promotion version history table for the marketing campaign, with the promotion version history table recording promotion attribute values for each promotion version at runtime, producing a treatment history table for the marketing campaign, with the treatment history table representing promotion instances given to a group, producing a contact history table for the marketing campaign, the contact history table recording which contact entities were in which groups at runtime, linking the promotion version history table, the treatment history table, and the contact history table, wherein the linking preserves referential integrity between the promotion version history table, the treatment history table, and the contact history table, and producing the contact history from the promotion version history table, the treatment history table, and the contact history table. | 12-26-2013 |
20130346185 | TRACKING RESPONSES TO PROMOTIONS - A computer implemented method for response tracking is described. The method includes obtaining one or more responses to one or more promotions, attributing the one or more responses to one or more treatment instances, with the one or more treatment instances correspond to a promotion version assigned to a group of contact entities at an execution of a computer implemented marketing campaign, and generating a response table, the response table including one or more entries, the entries in the response table being in accordance with attribution of the one or more responses to one or more treatment instances. | 12-26-2013 |
20130346216 | TECHNIQUES FOR ASSIGNING PROMOTIONS TO CONTACT ENTITIES - A computer implemented method for target group management is described. The method includes producing a table including one or more group entries corresponding to one or more defined contact group entities with each of the entries having a first set of group attributes, and producing a visual representation of a marketing campaign, the representation including one or more instances of defined contact group entities, with the one or more instances having a second set of group attributes and with the representation linked to the table according to the second set of group attributes. | 12-26-2013 |