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| 20080274131 | Molecular antigen arrary - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses. | 11-06-2008 |
| 20110293649 | In Vivo Activation of Antigen Presenting Cells for Enhancement of Immune Responses Induced by Virus Like Particles - The invention relates to the finding that stimulation of antigen presenting cell (APC) activation using substances such as anti-CD40 antibodies or DNA oligomers rich in non-methylated C and G (CpGs) can dramatically enhance the specific T cell response obtained after vaccination with recombinant virus like particles (VLPs) coupled, fused or otherwise attached to antigens. While vaccination with recombinant VLPs fused to a cytotoxic T cell (CTL) epitope of lymphocytic choriomeningitis virus induced low levels cytolytic activity only and did not induce efficient anti-viral protection, VLPs injected together with anti-CD40 antibodies or CpGs induced strong CTL activity and full anti-viral protection. Thus, stimulation of APC-activation through antigen presenting cell activators such as anti-CD40 antibodies or CpGs can exhibit a potent adjuvant effect for vaccination with VLPs coupled, fused or attached otherwise to antigens. | 12-01-2011 |
| 20110305723 | Molecular Antigen Array - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses. | 12-15-2011 |
| 20120114674 | Molecular Antigen Array - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses. | 05-10-2012 |
| 20130315949 | Molecular Antigen Array - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses. | 11-28-2013 |
| 20150202281 | Molecular Antigen Array - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses. | 07-23-2015 |
| 20150320855 | IN VIVO ACTIVATION OF ANTIGEN PRESENTING CELLS FOR ENHANCEMENT OF IMMUNE RESPONSES INDUCED BY VIRUS-LIKE PARTICLES - The invention relates to the finding that stimulation of antigen presenting cell (APC) activation using substances such as anti-CD40 antibodies or DNA oligomers rich in non-methylated C and G (CpGs) can dramatically enhance the specific T cell response obtained after vaccination with recombinant virus like particles (VLPs) coupled, fused or otherwise attached to antigens. While vaccination with recombinant VLPs fused to a cytotoxic T cell (CTL) epitope of lymphocytic choriomeningitis virus induced low levels cytolytic activity only and did not induce efficient anti-viral protection, VLPs injected together with anti-CD40 antibodies or CpGs induced strong CTL activity and full anti-viral protection. Thus, stimulation of APC-activation through antigen presenting cell activators such as anti-CD40 antibodies or CpGs can exhibit a potent adjuvant effect for vaccination with VLPs coupled, fused or attached otherwise to antigens. | 11-12-2015 |
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| 20090119701 | METHOD, COMPUTER PROGRAM PRODUCT, AND APPARATUS FOR DELIVERING INFORMATION AND COMMANDS REGARDING A MEDIA PROGRAM - A method, a computer program product, and apparatus are provided for delivering information and commands regarding a media program. An advertisement is provided that allows a user to request more information about the media program by clicking on or otherwise selecting the advertisement. The information may be based on the identity of the user. The information may include programming guide information regarding the media program that is available to an associated set top box of the user. The user may also be able to send commands, such as record the media program or set up a reminder about the media program, through a DVR scheduling facility to the set top box. The set top box may be able to send an acceptance of the command or a notice of conflict to the user through the DVR scheduling facility. | 05-07-2009 |
| 20110078023 | ADVERTISEMENTS WITHIN TELEVISION ADVERTISEMENTS - One or more devices send, over a network, an advertisement for presentation by a video client, where the advertisement includes a trigger for secondary advertising content that is presented, within a hotspot designated in the primary advertisement, as part of the primary advertisement. The one or more devices receive, via the network, a notification from the video client that a user has selected the trigger and determine, based on the notification, particular secondary advertising content to be presented to the user. The one or more devices send, over the network, instructions to the video client to retrieve the particular secondary advertising content for presentation to the user. | 03-31-2011 |
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| 20080268947 | CROSS PLATFORM GAMING - A first game server is configured to provide a game to a first category of user device. A second game server is configured to provide the game to a second category of user device. A game manager is configured to receive a request from a user device for the game application and to assign the request to one of the first game server and the second game server according to whether the user device is included in the first category of user device or the second category of user device. | 10-30-2008 |
| 20100169916 | Systems and Methods For Efficient Messaging And Targeted IP Multicast Advertisement In Communication Networks - Systems, apparatus, methods and computer readable mediums for efficient and unconstrained information distribution and IP multicasting are provided. An exemplary method may include receiving, from a set top box, information indicative of criteria associated with targeted advertisement; and determining, at a set top box, whether the criteria corresponds to a characteristic of a household at which the criteria is received. The method may also include joining, from a set top box, a multicast group associated with the criteria in the event the criteria is determined to correspond to the characteristic of the household at which the criteria is received. The method may also include receiving, via multicast, at a set top box, the targeted advertisement associated with the criteria; and displaying, at a video display device, the targeted advertisement. The exemplary method may allow efficient and unconstrained information distribution leading to improved application quality and performance. | 07-01-2010 |
| 20100313217 | METHODS AND SYSTEMS FOR RECOVERING FROM ERRORS ASSOCIATED WITH ADVERTISEMENT STREAMS - An exemplary method includes switching, by a media content access subsystem, from a program stream to an advertisement stream in response to a switching instruction received by the media content access subsystem, detecting, by the media content access subsystem, a predetermined number of markers included within the advertisement stream, the predetermined number of markers indicative of an error associated with the advertisement stream, and switching, by the media content access subsystem, from the advertisement stream to another media content stream in response to the detecting of the predetermined number of markers. Corresponding methods and systems are also disclosed. | 12-09-2010 |
| 20110179356 | Methods and Systems for Dynamically Inserting an Advertisement into a Playback of a Recorded Media Content Instance - An exemplary method includes maintaining data representative of a recorded media content instance comprising a media content program and a first advertisement and an index file corresponding to the recorded media content instance, playing back the recorded media content instance in accordance with timestamp data and storage location data included in the index file, dynamically replacing, during the playback of the recorded media content instance, a portion of the storage location data in the index file that corresponds to the first advertisement with storage location data corresponding to a second advertisement, and presenting the second advertisement in place of the first advertisement during the playback of the recorded media content instance in accordance with the modified index file. Corresponding methods and systems are also described. | 07-21-2011 |
| 20110191798 | Dynamic Advertisement Insertion Methods and Systems - An exemplary method includes maintaining data representative of a plurality of advertisements each having one of a plurality of different resolutions, detecting a message indicative of an upcoming advertisement break in a media content program being transmitted to a media content access device by way of a content channel, detecting a resolution of the media content program, directing a dynamic advertisement delivery subsystem communicatively coupled to the media content access device to dynamically transmit a subset of the advertisements by way of one or more advertisement channels, wherein each advertisement included in the subset has the same resolution as the resolution of the media content program, and distributing tuning information associated with each of the one or more advertisement channels to the media content access device prior to an occurrence of the advertisement break. Corresponding methods and systems are also disclosed. | 08-04-2011 |
| 20110209175 | Methods and Systems for Synchronizing Delivery of Media Content Streams Having Different Resolutions - An exemplary method includes processing a first program stream representative of media content having a first resolution and a second program stream representative of the media content having a second resolution, generating a single advertisement stream representative of advertisement content having a third resolution, detecting a transmission lag between the first and second program streams, dynamically synchronizing the first and second program streams to substantially remove the detected transmission lag, transmitting the synchronized first program stream by way of a first content channel, the synchronized second program stream by way of a second content channel, and the advertisement stream by way of an advertisement channel, and directing a media content access device to switch from being tuned to the second content channel to being tuned to the advertisement channel during an advertising break in the media content. Corresponding methods and systems are also disclosed. | 08-25-2011 |
| 20110211049 | Methods and Systems for Presenting Three-Dimensional Video Content - An exemplary method includes receiving, by a three-dimensional (“3D”) adapter subsystem separate from and communicatively coupled to a display device, a 3D video content stream comprising data representative of 3D video content, directing, by the 3D adapter subsystem, the display device to generate and display the 3D video content in accordance with the 3D video content stream, and calibrating, by the 3D adapter subsystem, the display of the 3D video content in accordance with one or more attributes of the display device. Corresponding methods and systems are also described. | 09-01-2011 |
| 20120151520 | METHODS AND SYSTEMS FOR RECOVERING FROM ERRORS ASSOCIATED WITH ADVERTISEMENT STREAMS - An exemplary method includes switching, by a media content access subsystem, from a program stream to an advertisement stream in response to a switching instruction received by the media content access subsystem, detecting, by the media content access subsystem, a predetermined number of markers included within the advertisement stream, the predetermined number of markers indicative of an error associated with the advertisement stream, and switching, by the media content access subsystem, from the advertisement stream to another media content stream in response to the detecting of the predetermined number of markers. Corresponding methods and systems are also disclosed. | 06-14-2012 |
| 20130103480 | PROVIDING COUPONS - A device is configured to receive, from a first mobile device of a first user of a group of users, information identifying a first location of the first mobile device and to receive, from a second mobile device of a second user of the group, a second location of the second mobile device. The device is further configured to determine a geographic area of a venue associated with a coupon. The device is also configured to match the coupon to the group when the first location and the second location are within the geographic area, and transmit information associated with the matched coupon to the first mobile device and the second mobile device. The group is organized by the first user or the second user for a plurality of users to receive coupons for a particular type of service associated with the matched coupon. | 04-25-2013 |
| 20130219424 | AD REPLACEMENT - Devices, methods, and storage media provide for receiving an airing of a program and a national ad; recording the program and the national ad; identifying an age of the national ad; comparing the age of the national ad to a threshold time period; and obtaining a replacement national ad in response to a comparison indicating that the age of the national ad exceeds the threshold time period. | 08-22-2013 |
| 20140153581 | PRIORITY-BASED BUFFER MANAGEMENT - Media units are stored in a buffer, wherein an importance rating is assigned to each of the media units. At least some of the media units are selectively flushed from the buffer based on the importance rating. | 06-05-2014 |
| 20140172966 | SHARED SCHEDULING FOR CONTENT DELIVERY SYSTEMS - One or more servers may receive, from a first server, a first list of timeslots; receive, from a second server, a second list of timeslots; store the first list of timeslots and the second list of timeslots to form a shared list of timeslots; receive an update to the shared list of timeslots by the first server or by the second server; store the update to the shared list of timeslots; receive a first schedule from the first server; and receive a second schedule from the second server. The first server may generate the first schedule and the second server may generate the second schedule based on information stored by the shared list of timeslots. The one or more servers may provide a particular content file to a user device in accordance with information associated with the first schedule or the second schedule. | 06-19-2014 |
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| 20110127348 | OXYGEN BLOWING LANCE WITH PROTECTION ELEMENT - An oxygen blowing lance for steel production, the lance having a protection element. The end of a main oxygen tube at the lance head has a cover shell with outlets. An oxygen outlet nozzle is removably and exchangeably fastened to each outlet. The protection element is provided removably and exchangeably at the lance head end of the oxygen blowing lance. An intermediate space is present between the lance head end of the oxygen blowing lance and the protection element. Penetrations are provided in the protection element, the oxygen outlet nozzles passing through the penetrations from the shell outward, and a gap remains between the oxygen outlet nozzle and the protection element. A protective gas line feeds into the intermediate space between the lance head end of the oxygen blowing lance and the protection element. A method for operating the oxygen blowing lance is also described. | 06-02-2011 |
| 20110290075 | Nozzle for Injecting Gas Containing Oxygen Into a Pig Iron Device Having an Injector Insertion Pipe - An injector insert pipe is arranged in the gas channel of a nozzle for injecting oxygen-containing gas into a pig iron production unit, wherein an interspace which surrounds the pipe is present over the entire pipe length between the wall of the gas channel and the pipe outer wall . The pipe extends at least as far as the nozzle end face which contains the mouth of the gas channel. The pipe space is connected to an oxygen-containing gas feed line, and the interspace is connected to a protective gas supply line. In a process, oxygen-containing gas is fed into the pipe space, which after it has flowed through the pipe, enters the production unit at an entry velocity, and the interspace is simultaneously flowed through by a gas which exits into the production unit at an exit velocity, wherein the entry velocity is greater than the exit velocity. | 12-01-2011 |
| 20110294636 | Roll for supporting and conveying hot material, process for producing the roll, process for repairing a worn roll, weld filler and welding wire for producing a build-up weld | 12-01-2011 |
| 20120247966 | METHOD FOR ELECTROCHEMICAL COATING OF A SUBSTRATE BY MEANS OF BRUSH PLATING AND DEVICE FOR CARRYING OUT SAID METHOD - A method electrochemically coats a substrate by brush plating. Particles are applied to the surface to be coated via a separated line system before the carrier for the electrolytes. The electrolyte is added to the carrier via a line system. The advantageous result thereof is that an agglomeration of the particles can be prevented because only a short time passes after the application of the particles until the formation of the layer. A device for electrochemical coating has two line systems for the cited purpose. The highly stressed surface components of rollers in rolling mills can be partially coated by the method. | 10-04-2012 |
| 20130112112 | COATING FOR MACHINE PARTS USED IN THE PRODUCTION OF PIG IRON OR STEEL - A composition used for coating machine parts used in the production of pig iron or steel may include aluminum nitride (AlN) in a proportion of from 10% by weight to 40% by weight, one or more metal-oxidic substances in a proportion of from ≧2 to 10% by weight, of which at least one comes from the group consisting of aluminum oxide, zirconium oxide, and LD converter dust, and an inorganic binder in a proportion of up to 70% by weight, where the % by weight are based on the total weight of the composition. A suspension based on the composition, and the use of the composition or the composition suspension for coating machine parts used in the production of pig iron or steel, are also disclosed. | 05-09-2013 |
