Lea
Andrew Lea, Cheshire GB
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20140165003 | TOUCH SCREEN DISPLAY - Systems and methods are disclosed for a slide-in menu that provides extended actions for grid layouts on touch screen devices. The slide-in menu provides a signposted visual interface object for user interaction with an application that is discoverable and usable and that provides several selectable options for touch-screen users, while requiring minimal screen real estate and retaining touch target sizes for individual screen controls that is appropriate for touch screen users. The slide-in menu may be augmented with an additional plurality of menu options and with a “more” button that displays the additional plurality of menu options. | 06-12-2014 |
Andrew Lea, Chester GB
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20140195979 | INTERACTIVE USER INTERFACE - A system and method for providing a selection interface on a touch screen device is disclosed. The selection interface depicts a claw for grasping. A progress indicator is provided by varying the motion of the claw. A completion indicator is also provided by depicting the claw in an open state or a closed state, and by moving the claw into a target region. | 07-10-2014 |
Benjamin Lea, Redditich GB
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20120125464 | FLUID DELIVERY SYSTEMS - A fluid delivery system has an inner pipe ( | 05-24-2012 |
Chin Tau Lea, Hong Kong CN
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20130148506 | BUFFERLESS NONBLOCKING NETWORKS ON CHIP - Network on Chips (NoC)s with a bufferless and nonblocking architecture are described. Core processors are communicatively coupled together on a substrate with a set of routing nodes based on nonblocking process. A network component routes data packets through the routing nodes and the core processors via communication links. A bufferless cross bar switch facilitates the communication of the data packets and/or path setup packets through the communication links among source processors and destination processors. The communication links include one or more channels, in which a channel comprises a data sub-channel, an acknowledgement sub-channel and a release sub-channel. | 06-13-2013 |
Chin Tau Lea, Ma On Shan HK
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20090141624 | Method and System for A Novel Flow Admission Control Framework - This invention presents a new FAC framework that keeps the stateless property of the Internet, allows statistical multiplexing gains, and is capable of handling admission control of both TCP and UDP flows. | 06-04-2009 |
Chin Tau Lea, New Territories HK
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20130083793 | SCALABLE 3-STAGE CROSSBAR SWITCH - Systems and methods are presented relating to a three stage crossbar based switching system and a scheduling method for transmission of data packets and associated request and grant tokens. The first stage and third stage portions of the switching system contain TDM crossbars, which are interconnected by a middle stage set of crossbars. In an embodiment, the system switching module is a m×m crossbar switch comprising m inputs and m outputs. The switch has a size m | 04-04-2013 |
20160028554 | HANDOFF FREE WIRELESS NETWORK ARCHITECTURE - An Internet protocol (IP) based wireless communication network is provided that enables device mobility without handoffs. In an aspect, mobile device of the network is configured to broadcast, via a multicast channel, an anchor router solicitation message comprising a mobile device identifier that identifies the mobile device. The mobile device then receives, via the multicast channel, an assigned IP address from an anchor router device near the mobile device based on detection of the anchor router solicitation message by the anchor router device. The mobile device further employs the assigned IP address to connect with one or more other router devices in response to movement of the mobile device to cell areas of the one or more other router devices of the network. | 01-28-2016 |
Cinzia Lea, Winston Hills AU
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20110192783 | Potting Method - A membrane module includes at least one hollow fibre membrane; a first resin layer formed around an end of the at least one hollow fibre membrane; and a second resin layer chemically bound to the first resin layer, wherein the second resin layer is of greater flexibility than the first resin layer. | 08-11-2011 |
D. Andrew G. Lea, Vancouver CA
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20110116569 | WIRELESS DATA COMMUNICATION METHODS AND APPARATUS - A data communication system has a station that includes multiple antenna elements. The station communicates to the antenna elements by way of digital data channels. Each antenna is connected to an RF module that receives data by way of a corresponding digital data channel, encodes and transmits the data. Adaptive beamforming may be performed for interference mitigation. Embodiments use the strength of pilot signals and/or error vector magnitudes as cost functions for an adaptive beamforming alogorithm such as optimum combining. Unused sub-carriers may be applied to provide in-band communication to facilitate channel switching, data reallocation and other interference mitigation strategies. | 05-19-2011 |
David Andrew G. Lea, Vancouver CA
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20130044028 | INTELLIGENT BACKHAUL RADIO AND ANTENNA SYSTEM - A intelligent backhaul radio have an advanced antenna system for use in PTP or PMP topologies. The antenna system provides a significant diversity benefit. Antenna configurations are disclosed that provide for increased transmitter to receiver isolation, adaptive polarization and MIMO transmission equalization. Adaptive optimization of transmission parameters based upon side information provided in the form of metric feedback from a far end receiver utilizing the antenna system is also disclosed. | 02-21-2013 |
20130273974 | INTELLIGENT BACKHAUL RADIO AND ANTENNA SYSTEM - A intelligent backhaul radio have an advanced antenna system for use in PTP or PMP topologies. The antenna system provides a significant diversity benefit. Antenna configurations are disclosed that provide for increased transmitter to receiver isolation, adaptive polarization and MIMO transmission equalization. Adaptive optimization of transmission parameters based upon side information provided in the form of metric feedback from a far end receiver utilizing the antenna system is also disclosed. | 10-17-2013 |
20140184455 | BACKHAUL RADIO WITH AN APERTURE-FED ANTENNA ASSEMBLY - Directive gain antenna elements implemented with an aperture-fed patch array antenna assembly are described. A feed network for the aperture-fed patch array may include offset apertures and may also include meandering feed lines. Scalable aperture shapes and orientations that can be used with antennas operating at any frequency and with dual orthogonal polarizations are also disclosed. Directive gain antenna elements implemented with arrays of orthogonal reflected dipoles are also described with optimal feed networks and parasitic elements to achieve desired directive gain characteristics. Such arrayed dipole antennas feature dual orthogonal polarizations with assembly tabs that lower cost and improve reliability. Backhaul radios that incorporate said antennas are also disclosed. | 07-03-2014 |
20140184457 | BACKHAUL RADIO WITH A SUBSTRATE TAB-FED ANTENNA ASSEMBLY - Directive gain antenna elements implemented with an aperture-fed patch array antenna assembly are described. A feed network for the aperture-fed patch array may include offset apertures and may also include meandering feed lines. Scalable aperture shapes and orientations that can be used with antennas operating at any frequency and with dual orthogonal polarizations are also disclosed. Directive gain antenna elements implemented with arrays of orthogonal reflected dipoles are also described with optimal feed networks and parasitic elements to achieve desired directive gain characteristics. Such arrayed dipole antennas feature dual orthogonal polarizations with assembly tabs that lower cost and improve reliability. Backhaul radios that incorporate said antennas are also disclosed. | 07-03-2014 |
20140329562 | Intelligent Backhaul Radio With Adaptive Channel Bandwidth Control - A intelligent backhaul radio have an advanced antenna system for use in PTP or PMP topologies. The antenna system provides a significant diversity benefit. Antenna configurations are disclosed that provide for increased transmitter to receiver isolation, adaptive polarization and MIMO transmission equalization. Adaptive optimization of transmission parameters based upon side information provided in the form of metric feedback from a far end receiver utilizing the antenna system is also disclosed. | 11-06-2014 |
20150084826 | APERTURE-FED, STACKED-PATCH ANTENNA ASSEMBLY - Directive gain antenna elements implemented with an aperture-fed patch array antenna assembly are described. A feed network for the aperture-fed patch array may include offset apertures and may also include meandering feed lines. Scalable aperture shapes and orientations that can be used with antennas operating at any frequency and with dual orthogonal polarizations are also disclosed. Directive gain antenna elements implemented with arrays of orthogonal reflected dipoles are also described with optimal feed networks and parasitic elements to achieve desired directive gain characteristics. Such arrayed dipole antennas feature dual orthogonal polarizations with assembly tabs that lower cost and improve reliability. Backhaul radios that incorporate said antennas are also disclosed. | 03-26-2015 |
20150194999 | BACKHAUL RADIO WITH HORIZONTALLY OR VERTICALLY ARRANGED RECEIVE ANTENNA ARRAYS - A intelligent backhaul radio have an advanced antenna system for use in PTP or PMP topologies. The antenna system provides a significant diversity benefit. Antenna configurations are disclosed that provide for increased transmitter to receiver isolation, adaptive polarization and MIMO transmission equalization. Adaptive optimization of transmission parameters based upon side information provided in the form of metric feedback from a far end receiver utilizing the antenna system is also disclosed. | 07-09-2015 |
Derek R. Lea, Paisley GB
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20130327070 | CONTROL SYSTEM FOR A REFRIGERATED MERCHANDISER - A refrigerated merchandiser including a case defining a product display area supporting product and an evaporator disposed in an air passageway in fluid communication with the product display area via an outlet to direct a refrigerated airflow into the product display area. The merchandiser also includes a control system in communication with and programmed to control the refrigeration system so that the product display area is maintained within a predetermined temperature range. The control system also varies the temperature of the refrigerated airflow through the outlet above an airflow temperature threshold between about 35 degrees Fahrenheit and 41 degrees Fahrenheit at least once during a predetermined time period to avoid formation of frost on the evaporator while maintaining the product display area within the predetermined temperature range. | 12-12-2013 |
Edward Lea, London GB
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20150206139 | TWO DEVICE AUTHENTICATION MECHANISM - The present invention relates to method for authenticating a user. The method includes the steps of: a second user device requesting authentication from a third party server; the third party server requesting an authentication token from a gateway server; the gateway server generating a transaction ID and transmitting an authentication token to the second user device, wherein the authentication token incorporates the transaction ID; the second user device outputting the authentication token; a first user device receiving the outputted authentication token; the first user device transmitting an authentication request to an application server, wherein the request includes the transaction ID extracted from the authentication token and a user identifier; and the application server verifying the authentication request and authenticating the user. A system for authenticating a user comprising two user devices and a server is also described. | 07-23-2015 |
20150222435 | IDENTITY GENERATION MECHANISM - The present invention relates to a method for generating an identity for a user. The method including the steps of: a first user device obtaining an identifier; the first user device generating a public-private key pair; the first user device transmitting a first request, including the identifier and the public key, to a server; the server generating an authentication token associated with the identifier and transmitting that token for receipt by an address associated with the user; the first user device receiving the authentication token via the address of the user; the first user device transmitting a second request, wherein at least a part of the second request is derived from the authentication token and at least a part of the second request is signed by the private key; and the server using the public key to verify the second request and validate the identifier as an identity for the user. A system for generating an identity for a user, and user device and server for use with the system are also disclosed. | 08-06-2015 |
20150281340 | DATA COMMUNICATIONS METHOD AND SYSTEM - The present invention relates to a data communications method. The method coordinates data communication between a first and second user device in a system including a first and second server, by the second server generating a unique identifier and transmitting the identifier and a resource location for receipt by the first user device via the first server; the first user device requesting a resource at the resource location; the second server transmitting the resource including a second executable component to the first user device; the first user device executing the second component to create a connection (such as a two-way socket) between the first user device and the second server; the second user device receiving the identifier; the second user device using the identifier to claim the connection to the first user device from the second server; and the second server coordinating data communication between the first and second user device. A data communication system, and a server and user devices for use with the system are also disclosed. | 10-01-2015 |
Espen Lea, Sola NO
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20120067267 | IMPROVED DEVICE AND METHOD FOR FORMING AN ANCHOR SPREAD - The invention is a method for mooring a marine vessel (P) using three or more anchor lines ( | 03-22-2012 |
Garry Richard Lea, Wamboin AU
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20130024437 | ACTIVITY RECORDAL METHOD AND SYSTEM - An activity recordal method comprising electronically monitoring for occurrence of events pertaining to one or more activities, electronically associating information relating to said events with respective activities, recording said information relating to said events with data indicative of said respective activities in a database, electronically generating reporting data from said information relating to said events recorded in said database, and electronically outputting said reporting data. | 01-24-2013 |
Graham Lea, Oxford Cluny GB
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20160075579 | Methods of Making Purified Water from the Fischer-Tropsch Process - The Fischer-Tropsch (FT) process creates significant amounts of water. This FT produced water contains significant amounts of organic impurities. The invention provides methods of treating FT produced water. Surprisingly, it was discovered that the FT produced water could be successfully treated in a membrane bioreactor (MBR) according to relatively simple and more efficient steps; for example, by adjusting the pH of the water in the range of 4.2 to 5.8 or treating the FT produced water in a stripper where the distillate product stream and a reflux stream returning to the stripper have the same composition. In a related aspect, water compositions are described. | 03-17-2016 |
Jeremy Lea, Congleton GB
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20090195776 | HANDHELD SPECTROMETER INCLUDING WIRELESS CAPABILITIES - A method for collecting and analyzing spectrum data to identify a composition of a sample material is described. The method includes obtaining a sample material, receiving a geographical location of the sample material at a handheld instrument, and analyzing the sample material to obtain sample spectrum data using the handheld instrument. The method also includes determining whether to perform an analysis of the sample spectrum data using the handheld instrument, or to perform the analysis of the sample spectrum data using a remote computer. The method also includes determining a composition of the sample material based on an analysis of the sample spectrum data and recording in a memory area at least one of the composition and the geographical location of the sample material. | 08-06-2009 |
Jungsu Lea, Seoul KR
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20120064865 | MOBILE TERMINAL AND CONTROL METHOD THEREOF - A communication terminal includes a wireless communication unit configured to receive a phone event and transmit an indication message, a travel state determining unit configured to determine whether or not a vehicle is traveling based upon vehicle state information when the phone event is received, and a controller configured to transmit an indication message to an originating terminal of the received phone event when it is determined that the vehicle is traveling. | 03-15-2012 |
Leslie Michael Lea, Oxfordshire GB
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20090139658 | PLASMA PROCESSING APPARATUS - A slotted conducting cylinder ( | 06-04-2009 |
Michael C. Lea, Berkshire GB
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20090135603 | BACK SIDE PLATE ILLUMINATION FOR BIOLOGICAL GROWTH PLATE SCANNER - A biological growth plate scanner includes a multi-color illumination system that illuminates a biological growth plate with different illumination colors. A monochromatic image capture device captures images of the biological growth plate during illumination of the growth plate with each of the illumination colors. A processor combines the images to form a composite multi-color image, and/or individual components of the composite image, and analyzes the composite image to produce an analytical result such as a colony count or a presence/absence result. The biological growth plate scanner may include both front and back illumination components. The back illumination component may include a diffuser element disposed under the biological growth plate. The diffuser element receives light from one or more laterally disposed illumination sources, and distributes the light to illuminate a back side of the biological growth plate. The illumination sources in the front and back illumination components may take the form of sets of light emitting diodes (LEDs) that can be independently controlled by the processor. | 05-28-2009 |
Peter Lea, Toronto CA
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20080220980 | Method to Measure Dynamic Internal Calibration True Dose Response Curves - A method of determining an amount of analyte in a sample solution is provided. The method involves the use of an assay device that has a substantially planar assay surface. The surface has a plurality of calibration dots a test dot printed thereon. The calibration dots contain pre-determined quantities of the analyte while the test dot includes a capture antibody for binding to the analyte. The analyte is mixed into a solution having a sample antibody for the analyte, where the antibody is labeled with a detectable marker. The sample solution is introduced into the loading portion of the assay device for delivery to said reading portion. The next step is to measure the intensity of detectable marker in the calibration dots. With the data obtained, one then prepares a calibration curve correlating the amount of analyte in said calibration dots to said intensity of detectable marker. The intensity of detectable marker in the test dot can be measures and the amount of analyte present in said test dot calculated by comparing the intensity of detectable marker to the amount of analyte corresponding to the intensity in said calibration curve. | 09-11-2008 |
20080259321 | System and Method for Rapid Reading of Macro and Micro Matrices - An analyte reading system which includes a reader unit for rapidly detecting and evaluating the outcome of an assay to measure the presence of analytes in a sample. Quantitative and qualitative measurements of analyte concentration in a sample may be rapidly obtained using the reader device with algorithms which ascertain the nature of the assay and perform a comparison against a calibration sample. The reader device scans preset areas of an assay device in order to provide focal points for the reader device and evaluate the volume of the test sample in the assay device. The reading portion of the assay slide has at least one test dot for detecting the presence of the analyte and the signal intensity of the labelled analyte, and processes the detected signal using an algorithm which provides an accurate output measurement indicating the quantity of the analyte in the test sample. The reader device can read the analyte as a random array format, print and read the analyte to be measured in a fixed array format, and print and read the analyte in a hybrid format consisting of both fixed and random arrays. | 10-23-2008 |
20080269075 | Method and Device to Optimize Analyte and Antibody Substrate Binding by Least Energy Adsorption - The present invention provides a method of making an assay device for conducting an assay to detect a concentration of an analyte in a sample fluid. The assay devices would typically have a substantially planar surface having a series of site specific immobilized calibration spot arrays containing pre-determined quantities of the analyte printed thereon. In addition, a series of site specific immobilized test spot arrays, including capture antibody for binding the analyte protein is printed on the assay device. The method involves first modifying the planar surface to provide hydrophobic binding sites, hydrophilic linking and covalent bonding sites. Then the method requires printing the series of site specific immobilized test spot arrays and the series of site specific immobilized calibration spot arrays on the substantially planar surface. Applying the sample fluid to the assay device is the next step followed by testing a sensitivity of the assay and modulating ratios of the hydrophobic, hydrophilic and covalent binding sites in order to optimize the sensitivity of the assay. | 10-30-2008 |
20090074878 | Non-Toxic Water Soluble Inorganice Antimicrobal Polymer and Related Methods - The present invention provides a non-toxic water soluble, inorganic anti-microbial polymer for inactivating microorganisms. The polymer is obtained by forming an aqueous solution comprising alkali metal cations, phosphate anions, carbonate anions, and hydrogen ions. The polymer has antimicrobial activity while in suspension and forms a hard, contiguous, encapsulating antimicrobial transparent film when dry. The film physically disrupts encapsulated microorganisms as it is formed and once formed does not support surface microbial growth. | 03-19-2009 |
20110065134 | SYNTHETIC PEPTIDES IMMUNO-REACTIVE WITH RHEUMATOID ARTHRITIS AUTO-ANTIBODIES - Embodiments of the present invention relate to a three dimensional matrix of selected, synthetic peptide mimic sequences that are preferentially recognized by auto-antibodies, specifically by autoimmune antibodies, to be detected in patients afflicted with rheumatic arthritis, enabling enhanced sensitivity and specificity in detection of these antibodies in pre-symptomatic patients, in patients showing symptoms as well as patients confirmed positive for rheumatoid arthritis. | 03-17-2011 |
20110232125 | METHOD AND DEVICE TO REMOVE FLUID AND VAPOR - The present invention relates to a method and device for the removal of fluids and vapors in containment, from adjacent surfaces including supporting flat surfaces and substrates, such as protein spots printed in arrays and micro-array formats. This method and device removes fluids and vapors under controlled and repeatable conditions, enabling uniform phases for degree of drying incurred by objects, specimen and structures, including tissues, adsorbed particles and biological substrates, while reducing and preventing impact of meniscus phase surface tension forces. | 09-29-2011 |
20110281028 | Method for double-dip substrate spin optimization of coated micro array supports - Described is a method for preparing a substrate-coated support for use in micro-array devices. The method comprises the steps of applying a first coat of substrate to a support, making the substrate coating ramp by subjecting the coated support to centripetal forces, adding a second coat of substrate to the resulting support having a ramping planar coat, and subjecting the coated support to centripetal forces for a second time to produce a substrate-coated membrane in which the thickness of the substrate layer is uniform across the entire coated surface. | 11-17-2011 |
20110306511 | METHODS FOR MULTIPLEX ANALYTE DETECTION AND QUANTIFICATION - The application refers to a method for detecting and quantifying multiple target analytes in a test sample using a single reaction vessel. The method uses a reaction vessel (a multi-well plate), which comprises a microarray of: (a) calibration spots, each having a predetermined quantity of the target analyte; and (b) capture spots, each having an agent (antibody) that selectively binds the target analyte. The captured analytes and the calibration spots are detected with fluorescently labelled antibodies specific for each different target analyte. The calibration spots are used to generate calibration curves that allow the measurement of the concentration of the different target analytes. The application also refers to a method for detecting and quantifying biomarkers that are useful for diagnosing rheumatoid arthritis. More specifically, the application discloses the use of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP), as capture spots. Finally, based on the above method, it is proposed a method for diagnosing or monitoring rheumatoid arthritis. | 12-15-2011 |
20120283122 | ANALYTE QUANTIFICATION MULTIPLEX MICROARRAYS COMBINING INTERNAL AND EXTERNAL CALIBRATION - The present invention relates to multiplex microarrays and methods for the quantification of analytes. In particular, the invention relates to improved methods which standardize a target analyte concentration in a test sample against a reference standardization curve derived from validated, approved and recognized reference standards for the target analyte of known concentrations. The present invention also relates to methods and checks for simultaneous measurement of confidence confirming normalization standards and controls. | 11-08-2012 |
20140031249 | MULTIPLEX MEASURE OF ISOTYPE ANTIGEN RESPONSE - Described are methods for simultaneous detection and quantifying multiple target analytes, including immunoglobulin isotypes and sub-classes, single and multiple protein antibodies within a test sample contained in a single reaction vessel. Such methods use reaction wells as on a multi-well plate, each single well comprising microarrays of calibration spots, each having a predetermined quantity of a target analyte; and capture spots, each having multiple agent antibodies, including isotypes and subclasses that specifically bind the target analytes. The captured analytes and the calibration spots are detected with fluorescently labeled antibodies specific for each different target analyte. Calibration spots generate calibration curves for quantitative determinations of different target analytes. Also described are methods for detecting and quantifying biomarkers, therapeutic proteins and patient derived antibodies; the use of secondary reagents to determine immunoglobulin classes Ig G, A, M, E and sub-classes including IgG1, IgG2, IgG3, IgG4 and IgA. The intensity of each fluorescent signal allows measurement of a specific immune response to a therapeutic protein and associated analytes; interrogates neutralizing effects of patient antibodies on therapeutic proteins, e.g., insulin therapy. | 01-30-2014 |
Peter Lea, Ontario CA
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20110201522 | ARRAY FLUORESCENCE EQUALIZATION METHOD - The present invention provides a method for fluorescence intensity equalization. The method involves providing an assay device having at least one immobilized array of molecular probes that bind to an analyte bound to a fluorescent marker; providing drying apparatus comprising an aspiration tube having open first and second ends, the second end of the aspiration tube being connected a vacuum source for applying a vacuum through said tube; placing the first end of the aspiration tube in proximity of said at least one immobilized array of molecular probes; and applying a vacuum through said aspiration tube for removing vapor from said at least one immobilized array of molecular probes. The application of the present invention provides for more reliable fluorescent signal intensity readings due to a reduction in signal quenching factors. | 08-18-2011 |
Robert William Lea, Preston GB
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20150301017 | METHODS OF DIAGNOSING PROLIFERATIVE DISORDERS - The present invention relates to methods of diagnosing and/or prognosing proliferative disorders, especially brain cancers (e.g. gliomas). In particular, the present invention provides a means to conveniently detect malignant tumours merely by assaying or analysing blood (particularly blood serum). Cytokines and/or angiogenesis factors in blood serum have been found to be surprisingly powerful at indicating the presence of brain cancers in a subject. Moreover, spectroscopic analysis, especially ATR-FTIR analysis, of a blood sample has been demonstrated to be surprisingly effective at producing a signature that can be correlated with the presence, extent, severity, or aggressiveness of malignant tumours in a subject. | 10-22-2015 |
Rod A. Lea, Wellington NZ
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20120004266 | DOPAMINE-BETA-HYDROXYLASE GENETIC POLYMORPHISM AND MIGRAINE - The invention provides a method of determining whether or not an individual has a predisposition to migraine including the step of determining whether an isolated nucleic acid obtained from the individual comprises a nucleotide sequence corresponding to at least a fragment of a dopamine β-hydroxylase (DBH) gene promoter, wherein the presence of a −1021C→T single nucleotide polymorphism (SNP) in said nucleotide sequence indicates whether or not said individual has an increased predisposition to migraine compared to an individual without the polymorphism. DBH −1021C/C homozygotes are particularly susceptible to migraine. The −1021T allele may exert a protective effect. The method is particularly suited to detection of a predisposition to migraine with aura in females. The invention also provides a diagnostic kit for detecting a −1021C→T SNP associated with migraine. The method and kit may facilitate selection of individuals for migraine therapy which targets the dopaminergic system. | 01-05-2012 |
Rodger Lea, Vancouver CA
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20090150492 | Initializing Relationships Between Devices In A Network - A relationship initiation between devices in a network is described. According to one embodiment, persona information is exchanged between devices in a network. Based upon the persona information, a user of a device may initiate a relationship with another device. | 06-11-2009 |
Stephen A. Lea, Winston Hills AU
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20120266887 | DOUBLE-ENDED BLOWER AND VOLUTES THEREFOR - A variable speed blower for Continuous Positive Airway Pressure (CPAP) ventilation of patients includes two impellers in the gas flow path that cooperatively pressurize gas to desired pressure and flow characteristics. Thus, the blower can provide faster pressure response and desired flow characteristics over a narrower range of motor speeds, resulting in greater reliability and less acoustic noise. | 10-25-2012 |
Stephen A. Lea, Bella Vista AU
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20130280055 | DOUBLE-ENDED BLOWER AND VOLUTES THEREFOR - A variable speed blower for Continuous Positive Airway Pressure (CPAP) ventilation of patients includes two impellers in the gas flow path that cooperatively pressurize gas to desired pressure and flow characteristics. Thus, the blower can provide faster pressure response and desired flow characteristics over a narrower range of motor speeds, resulting in greater reliability and less acoustic noise. | 10-24-2013 |
Stephen Anthony Lea, Winston Hills AU
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20140041663 | MULTIPLE STAGE BLOWERS AND VOLUTES THEREFOR - A multiple stage variable speed blower for Continuous Positive Airway Pressure (CPAP) ventilation of patients includes two impellers in the gas flow path that cooperatively pressurize gas to desired pressure and flow characteristics. Thus, the multiple stage blower can provide faster pressure response and desired flow characteristics over a narrower range of motor speeds, resulting in greater reliability and less acoustic noise. | 02-13-2014 |
Stephen Anthony Lea, Sydney AU
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20150306336 | BREATHABLE GAS APPARATUS WITH HUMIDIFIER - A CPAP device for delivering pressurized, humidified breathable gas for a patient includes a flow generator configured to pressurize a flow of breathable gas. The flow generator includes an air outlet and a removable water container configured to humidify the pressurized breathable gas received from the flow generator. The water container includes an air inlet and an air outlet. The CPAP device further includes a first elastomeric face seal configured to sealingly abut against a substantially flat portion of the water container surrounding the water container air inlet, the first elastomeric face seal being located at an intermediate position between the flow generator air outlet and the water container air inlet when the water container is placed into position to pneumatically communicate with the flow generator. In addition, the CPAP device includes a second elastomeric face seal, a portion of which is configured to sealingly abut against a substantially flat external surface portion of the water container surrounding the water container air outlet. | 10-29-2015 |
Susan Lea, Oxford GB
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20110059885 | TREATMENT OF DISEASES AND CONDITIONS MEDIATED BY EICOSANOIDS - The method of the invention relates to an OmCI polypeptide or a polynucleotide encoding an OmCI polypeptide for the treatment of a disease or condition mediated by a leukotriene or hydroxyeicosanoid. | 03-10-2011 |
20150190494 | NEISSERIA MENINGITIDIS FHBP VARIANT AND ITS USE FOR VACCINATION - The invention relates to a modified V2 fHbp having increased stability over a wild type V2 fHbp; a modified V2 fHbp having an amino acid sequence with at least 85% identity to the sequence of Seq ID No: 1, wherein both Ser | 07-09-2015 |
20150361183 | INHIBITION OF THE COMPLEMENT SYSTEM - Agents and compounds which can be used to modulate the activity of the complement system, novel biological targets associated with such modulation, and pharmaceutical compositions, medicaments and methods of treatment for use in preventing, ameliorating or treating diseases that are characterised by inappropriate complement activity. These diseases include age-related macular degeneration (AMD), meningitis, renal disease, autoimmune disease and inflammation. Therapeutic antibodies and screening assays for identifying agents useful in treating these diseases are also provided. | 12-17-2015 |
Susan M. Lea, Oxford GB
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20120115773 | MODIFIED OMCI AS A COMPLEMENT INHIBITOR - The method of the invention relates to a modified OmCI polypeptide or a polynucleotide encoding a modified OmCI polypeptide which lacks LK/E binding activity and the use of such polypeptides and polynucleotides for the treatment of a disease or condition mediated by complement. | 05-10-2012 |
Susan Mary Lea, Oxford GB
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20160030544 | IMMUNOGENIC COMPOSITION TO NEISSERIA - The present invention provides an immunogenic composition capable of eliciting an immune response when administered to a human or non-human animal, wherein the composition comprises an isolated protein with one or more of the following properties: i) about 70, 75, 80, 85, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99 or more percent sequence identity to the protein of SEQ ID No: 1 or a fragment, derivative or analog thereof; ii) is a modified factor H binding protein, wherein the factor H binding protein has been modified at least at the position equivalent to position 318 as defined in FIG. | 02-04-2016 |
Susan Mary Lea, London GB
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20160108128 | ANTIBODIES THAT BIND TO JAGGED 1 - The present invention provides antibodies which bind to the Delta/Serrate/LAG-2 consensus sequence (DSL) domain of human Jagged 1 via novel epitopes comprising the residue E228, and inhibit the interaction between human Jagged 1 and its associated receptors. Said antibodies may be administered therapeutically in the treatment of tumours/cancer, preferably those associated with tumoural Jagged 1-mediated signalling and tumour microenvironmental processes in which Jagged 1 and/or Notch-mediated signalling has been implicated, including those comprising Jagged 1-mediated cross talk between the tumour and the tumour microenvironment. The present invention also provides pharmaceutical compositions comprising said antibodies, uses of said antibodies in therapy, hybridomas comprising and/or secreting said antibodies and cells or cell lines expressing said antibodies and humanised/deimmunised variants in recombinant form. | 04-21-2016 |