Kuramochi, JP
Akiko Kuramochi, Ibaraki JP
Patent application number | Description | Published |
---|---|---|
20100183733 | HAIR GROWTH-INHIBITING AGENT - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract). | 07-22-2010 |
20100184665 | METHOD FOR ACTIVATING RECEPTOR BY COFACTOR AND METHOD FOR UTILIZING LIGAND ACTIVITY - Using betaKlotho or a substance that increases or inhibits betaKlotho activity as an agent for controlling the activity of FGF21 mediated by an FGF receptor, the present invention provides a pharmaceutical composition comprising such betaKlotho or such substance as an active ingredient, particularly, a pharmaceutical composition for anti-metabolic syndrome, and further particularly, a pharmaceutical composition for therapeutic or preventive use associated with the control of blood glucose level. In addition, the present invention provides a screening system for each of a substance that enhances or suppresses betaKlotho activity, an FGF21-like active substance, and a betaKlotho-like active substance, which uses a cell system that has expressed an FGF receptor and/or betaKlotho on the surface thereof. | 07-22-2010 |
20100203055 | HAIR REGROWTH PROMOTER - It is intended to provide a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia by determining an endogenous factor that inhibits hair growth and screening for substances that inhibit the activity or expression of the endogenous factor. It has been found that FGF18 inhibits hair growth. A method of screening for substances that inhibit the activity of FGF18 or substances that inhibit the expression of FGF18 to thereby obtain candidates for the hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia is disclosed. Also disclosed is a hair growth promoting agent, hair regrowth promoting agent or therapeutic for alopecia comprising, as an active ingredient(s), a substance that inhibit the activity of FGF18 and/or a substance that inhibits the expression of FGF18 such as a partial peptide of FGF18 or a | 08-12-2010 |
20100286042 | Medicinal Composition Containing Highly Functionalized Chimeric Protein - There is provided an FGF2 substitute containing medicinal composition which comprises, as an active ingredient, a chimeric protein comprising the amino acid sequence of an FGF1 protein in which a partial sequence including a sequence of at least positions 62-83 within a sequence of positions 41-83 is substituted with a partial sequence at the corresponding positions in the amino acid sequence of an FGF2 protein; and the remaining region is formed of the amino acid sequence of FGF1. In particular, this medicinal composition is used for wound healing and for the prevention and treatment of radiation-induced damage, and it exhibits a pharmacological action superior to that of an FGF2 medicinal composition, and further, it can be easily formulated into a preparation. | 11-11-2010 |
20120214740 | Medicinal Compositions Containing Highly Functionalized Chimeric Protein - There is provided an FGF2 substitute-containing medicinal composition which comprises, as an active ingredient, a chimeric protein comprising the amino acid sequence of an FGF1 protein in which a partial sequence including a sequence of at least positions 62-83 within a sequence of positions 41-83 is substituted with a partial sequence at the corresponding positions in the amino acid sequence of an FGF2 protein; and the remaining region is formed of the amino acid sequence of FGF1. In particular, this medicinal composition is used for wound healing and for the prevention and treatment of radiation-induced damage, and it exhibits a pharmacological action superior to that of an FGF2 medicinal composition, and further, it can be easily formulated into a preparation. | 08-23-2012 |
20120251455 | Hair Growth-Inhibiting Agent - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract). | 10-04-2012 |
Daisuke Kuramochi, Saitama JP
Patent application number | Description | Published |
---|---|---|
20100207345 | SADDLE-RIDE TYPE VEHICLE - A saddle-ride type vehicle with a swing arm swingably supported on a body frame. A shock absorber is connected to the body frame and the swing arm for applying a damping force. A shock absorber support member is suspended to the body frame in a vehicle width direction for supporting an upper end of the shock absorber. The shock absorber is supported on a central portion in the vehicle width direction of the shock absorber support member. The central portion in the vehicle width direction of the shock absorber support member is formed in a U-shape that is open at a lower side in a cross section taken along a longitudinal direction of the vehicle. An upper surface and a lower surface of the shock absorber support member are curved wherein a central portion lies above the end portion in the vehicle width direction. | 08-19-2010 |
20110120796 | MOTORCYCLE - Disclosed is a motorcycle fitted with a canister. A canister ( | 05-26-2011 |
Daisuke Kuramochi, Wako-Shi JP
Patent application number | Description | Published |
---|---|---|
20100051369 | CANISTER LAYOUT STRUCTURE IN MOTORCYCLE - A canister layout structure in a motorcycle includes a swing arm vertically swingably supported to a rear portion of a body frame and supporting a wheel, a canister located below the swing arm for trapping an evaporative fuel evaporated in a fuel tank, and a center stand pivotably supported to a lower portion of the body frame for making the body frame stand on a road surface when parking. The center stand is retractable to keep a horizontal position substantially parallel to a road surface during running. The canister is located above the center stand in its retracted condition. | 03-04-2010 |
Hideto Kuramochi, Kanagawa JP
Patent application number | Description | Published |
---|---|---|
20110155560 | SINTERED COMPLEX OXIDE, METHOD FOR PRODUCING SINTERED COMPLEX OXIDE, SPUTTERING TARGET AND METHOD FOR PRODUCING THIN FILM - A sintered complex oxide comprising metal oxide particles (a) having a hexagonal lamellar structure and containing zinc oxide and indium, and metal oxide particles (b) having a spinel structure and containing a metal element M (where M is aluminum and/or gallium), wherein the mean value of the long diameter of the metal oxide particles (a) is no greater than 10 μm, and at least 20% of the metal oxide particles (a) have an aspect ratio (long diameter/short diameter) of 2 or greater, based on the number of particles. | 06-30-2011 |
20130214215 | ZINC OXIDE SINTERED COMPACT, SPUTTERING TARGET, AND ZINC OXIDE THIN FILM - There is provided a zinc oxide sintered compact with a zirconium content of 10 to 1000 ppm, and a sputtering target containing the zinc oxide sintered compact. There is also provided a zinc oxide thin-film having a zirconium content of 10 to 2000 ppm and a resistivity of 10 Ω·cm or greater. | 08-22-2013 |
20140332735 | COMPLEX OXIDE SINTERED BODY, SPUTTERING TARGET, TRANSPARENT CONDUCTIVE OXIDE FILM, AND METHOD FOR PRODUCING SAME - The present invention provides a complex oxide sintered body | 11-13-2014 |
20150295116 | OXIDE SINTERED BODY, SPUTTERING TARGET USING IT, AND OXIDE FILM - To provide an oxide sintered body for a sputtering target, which is capable of adding specific elements to from an n-type semiconductor layer to a p-type semiconductor layer surface of a compound thin-film solar cell. | 10-15-2015 |
Hideto Kuramochi, Ayase-Shi JP
Patent application number | Description | Published |
---|---|---|
20130181173 | SINTERED COMPOSITE OXIDE, MANUFACTURING METHOD THEREFOR, SPUTTERING TARGET, TRANSPARENT CONDUCTIVE OXIDE FILM, AND MANUFACTURING METHOD THEREFOR - A sintered composite oxide | 07-18-2013 |
20130276879 | SINTERED OXIDE MATERIAL, METHOD FOR MANUFACTURING SAME, SPUTTERING TARGET, OXIDE TRANSPARENT ELECTRICALLY CONDUCTIVE FILM, METHOD FOR MANUFACTURING SAME, AND SOLAR CELL - The invention provides an oxide sintered compact | 10-24-2013 |
20150187548 | COMPOSITE OXIDE SINTERED BODY AND OXIDE TRANSPARENT CONDUCTIVE FILM - To provide a composite oxide sintered body from which an oxide transparent conductive film having lower light absorption properties in a wide wavelength region and having a low resistance can be obtained, and an oxide transparent conductive film. A composite oxide sintered body containing indium, zirconium, hafnium and oxygen, wherein the atomic ratio of the elements constituting the sintered body satisfies the following formulae, where In, Zr and Hf are respectively contents of indium, zirconium and hafnium: | 07-02-2015 |
Hiroyuki Kuramochi, Joso-Shi JP
Patent application number | Description | Published |
---|---|---|
20100226131 | LIGHTING EQUIPMENT - LEDs, a reflector, and a baffle are disposed on the underside of the equipment main body. An emission opening for emitting light of the LEDs and a reflection surface for emitting light of the LEDs from the emission opening by reflecting the same are provided in the reflector. The baffle is disposed outside the direct light emission area where direct light from the LEDs is emitted from the emission opening of the reflector. The direct light from the LEDs can be picked up without being blocked by the baffle, and the light pick-up efficiency can be improved. | 09-09-2010 |
Hiroyuki Kuramochi, Aichi JP
Patent application number | Description | Published |
---|---|---|
20110274561 | CEILING FAN - A ceiling fan includes a connecting portion fixed to a ceiling, an electric motor having a rotation shaft disposed on a lower portion of the connecting portion, a temperature detector provided on a lower portion of the electric motor for detecting a peripheral temperature, and a controller for estimating a room temperature based on the temperature detected by the temperature detector and driving the electric motor according to the estimated room temperature. | 11-10-2011 |
20130136603 | CEILING FAN - A ceiling fan includes a suspension part, a pipe, and a main body, the main body has a coupling part, an upper portion of the coupling part has a coupling hole, a lower portion of the pipe has a pipe hole, the coupling part is inserted into the pipe, a bolt inserted into the coupling hole and the pipe hole, and a nut. The bolt includes a threaded portion and a head having a curved surface that conforms to the shape of the outer surface of the pipe. The curved surface has a head direction guide part that guides the direction of the curved surface such that the curved surface is fixed in contact with the outer surface with the nut. | 05-30-2013 |
20130280077 | CEILING FAN - A ceiling fan includes a suspending unit and a ceiling fan body. The ceiling fan body includes a shaft; a motor; a plurality of blades; an upper body cover having a first opening, at a central part, for passing the shaft therethrough, and a second opening outside the first opening; and a lower body cover. The upper body cover rotates with the blades and has a first wall standing vertically between the first opening and the second opening. | 10-24-2013 |
20150086375 | CEILING FAN - A ceiling fan includes blade ( | 03-26-2015 |
Hiroyuki Kuramochi, Yokosuka-Shi JP
Patent application number | Description | Published |
---|---|---|
20110235334 | OPTICAL UNIT AND LIGHTING APPARATUS - According to one embodiment, an optical unit includes a light emitting module having a light emitting element, a supporting substrate supporting the light emitting module, a reflector controlling distribution of light from the light emitting module, and a heat sink thermally connected to the supporting substrate. | 09-29-2011 |
20110235335 | LIGHTING APPARATUS - A lighting apparatus according to an embodiment includes an optical unit and a body. The Optical unit includes a light emitting module that has a light emitting element, a reflector that controls distribution of light from the light emitting module, and a unit supporting member that supports the light emitting module and the reflector. A plurality of optical units are mounted to the apparatus body such that each optical unit is detachable. And the body includes an irradiating portion that has an opening through which the optical units irradiate light. | 09-29-2011 |
20140328068 | Lighting Apparatus - A lighting apparatus according to an embodiment includes an optical unit and a body. The Optical unit includes a light emitting module that has a light emitting element, a reflector that controls distribution of light from the light emitting module, and a unit supporting member that supports the light emitting module and the reflector. A plurality of optical units are mounted to the apparatus body such that each optical unit is detachable. And the body includes an irradiating portion that has an opening through which the optical units irradiate light. | 11-06-2014 |
20150260362 | Lighting Device - According to one embodiment, a lighting device includes: a first housing in which a lamp unit is provided; a second housing in which a power supply unit is provided; and a hinge member that allows the first housing to be capable of opening and closing with respect to the second housing. | 09-17-2015 |
Hiroyuki Kuramochi, Shizuoka JP
Patent application number | Description | Published |
---|---|---|
20140085862 | LIGHTING DEVICE - According to one embodiment, a lighting device includes a main body, a light source, a light transmitting cover, and a reflector. The main body is formed from metal. The light source has a substrate formed from ceramic and attached to the light source attachment portion of the main body, and a light emitting element mounted on the substrate. The light transmitting cover is formed from glass. The reflector is formed from metal. The reflector is held by the main body without contact with respect to the main body and the light source between the light source attachment portion and the light transmitting cover. Between the light source attachment portion and the light transmitting cover, parts irradiated with light emitted from the light emitting element do not contain resin except a part in the light source. | 03-27-2014 |
20140085902 | LUMINAIRE - According to one embodiment, a luminaire includes a main body made of metal, a light source, a reflector made of metal, a translucent cover made of glass, and an insulating member. The main body includes a light-source attaching section, an opening opposed to the light-source attaching section, a sidewall section, and a reflector supporting section. The reflector includes a flange section supported by the reflector supporting section in a non-contact manner and a reflection surface expanding from a daylight opening toward a floodlight opening. The translucent cover is provided on the floodlight opening side. The insulating member is configured to hold the flange section of the reflector and an outer edge portion of the translucent cover, and interposed between the flange section and the outer edge portion, and between the flange section and the reflector supporting section. | 03-27-2014 |
Hisayoshi Kuramochi, Kanagawa JP
Patent application number | Description | Published |
---|---|---|
20110068363 | LIGHT EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME - A method of manufacturing a light emitting device, including the steps of: (A) sequentially forming a first compound semiconductor layer of a first conduction type, an active layer, and a second compound semiconductor layer of a second conduction type different from said first conduction type, over a substrate; and (B) exposing a part of said first compound semiconductor layer, forming a first electrode over said exposed part of said first compound semiconductor layer and forming a second electrode over said second compound semiconductor layer, wherein said method further includes, subsequent to said step (B), the step of: (C) covering at least said exposed part of said first compound semiconductor layer, an exposed part of said active layer, an exposed part of said second compound semiconductor layer, and a part of said second electrode with an SOG layer. | 03-24-2011 |
20110075693 | SEMICONDUCTOR LASER - The present invention provides a semiconductor laser realizing reduced possibility that a wiring layer disposed in the air is broken even under severe environment of a large temperature difference. A trench is provided between adjacent ridges, and a wiring layer electrically connecting an upper electrode and a pad electrode is disposed in the air at least above the trench. The wiring layer in a portion above the trench has a flat shape or a concave shape which dents toward the trench. With the configuration, accumulation of strains in the wiring layer when the wiring layer repeats expansion and shrink under severe environment of a large temperature difference is suppressed. | 03-31-2011 |
Izumi Kuramochi, Hiratsuka-Shi, Kanagawa JP
Patent application number | Description | Published |
---|---|---|
20150343856 | Tire/Wheel Assembly and Tread Ring - A tire-wheel assembly comprises a wheel coupled to a rotating shaft; an elastic tube disposed on an outer side of the wheel with respect to a radial direction, the interior of the tube being filled with air; a rigid protective ring disposed on an outer side of the tube with respect to the radial direction separated from the wheel; and a tread ring disposed on an outer side of the protective ring with respect to the radial direction, an inner circumferential surface of the tread ring contacting an outer circumferential surface of the protective ring. | 12-03-2015 |
Izumi Kuramochi, Hiratsuka-Shi JP
Patent application number | Description | Published |
---|---|---|
20090211674 | NON-PNEUMATIC TIRE - Provided is a non-pneumatic tire in which buckling can be prevented without a weigh increase of the tire, the non-pneumatic tire including a spoke structure. The non-pneumatic tire is characterized in that, in the non-pneumatic tire where a spoke structure obtained by circumferentially arranging spokes intermittently at intervals, which radially couple together annular cylindrical outer member and cylindrical inner member, is joined to an inner peripheral side of a tread ring, at least some of a plurality of spaces each formed between two spokes adjacent to each other in the tire circumferential direction each have an air-containing structure. | 08-27-2009 |
Kiyoshi Kuramochi, Chiba-Shi JP
Patent application number | Description | Published |
---|---|---|
20100173067 | FILM FORMING APPARATUS AND FILM FORMING METHOD - An apparatus includes a holding mechanism that holds a substrate, a material container where a film-forming material is gasified, a release port for releasing the gasified film-forming material toward the substrate; a material container heating unit for heating the material container, a transport pipe that is detachably linked to the material container by a linking portion and serves to transport the gasified film-forming material from the material container to the release port, a transport pipe heating unit for heating a remaining zone of the transport pipe other than a portion in a vicinity of the linking portion, and a linking portion heating unit that is disposed independently from the transport pipe heating unit and serves for heating the portion of the transport pipe in the vicinity of the linking portion. | 07-08-2010 |
Masahiro Kuramochi, Hyogo JP
Patent application number | Description | Published |
---|---|---|
20100031001 | SERIAL MEMORY DEVICE AND SIGNAL PROCESSING SYSTEM - In a serial memory device which performs reception and transmission of command, address, and data via serial communication with a host controller, a base address holding circuit holds a base address which serves as a base for effective address calculation. An address operation circuit calculates an effective address based on the base address and an address input from the host controller. | 02-04-2010 |
Masaki Kuramochi, Ueda-Shi JP
Patent application number | Description | Published |
---|---|---|
20140182283 | HYDRAULIC PRESSURE GENERATOR - A hydraulic-pressure generator including: primary and secondary pistons displaced corresponding to displacement of a brake pedal; a first pressure chamber communicating with a first hollow in the primary piston and generating in brake fluid hydraulic pressure corresponding to the displacement of the primary piston; a second pressure chamber communicating with a second hollow in the secondary piston and generating in the brake fluid hydraulic pressure corresponding to the displacement of the secondary piston; one or more first communication openings formed in a peripheral wall surrounding the first hollow; and second communication openings formed in a peripheral wall surrounding the second hollow. The flow rate of the brake fluid through the one or more first communication openings is different from the flow rate of the brake fluid through the second communication openings. | 07-03-2014 |
Michio Kuramochi, Osaka JP
Patent application number | Description | Published |
---|---|---|
20090165534 | METHOD AND APPARATUS FOR TESTING LEAKAGE OF PIPE PASSAGE - A method for testing leakage of a pipe passage employs a flow rate of gas used in testing supplied to the inside of a pipe passage undergoing testing hermetically sealed on one side while detecting flow rate with a flow measuring device and pressure with a pressure detector, and detecting temperature of the gas used, and inputting the detected values of pressure, flow rate and temperature into a computation treatment apparatus, and internal capacity V | 07-02-2009 |
Mihoko Kuramochi, Sakura-Shi JP
Patent application number | Description | Published |
---|---|---|
20120265162 | ABSORPTIVE ARTICLE - In an absorptive article, fitting performance is improved by following the shape and movement of a body, and wrinkles in a blood discharge opening corresponding portion are eliminated and wearing comfort is improved by separating movement of each part from each other so that the blood discharge opening corresponding portion is not affected. | 10-18-2012 |
20140288520 | ABSORBENT ARTICLE - [Problem to be Solved] | 09-25-2014 |
Mitsuru Kuramochi, Ibaraki-Ken JP
Patent application number | Description | Published |
---|---|---|
20090073493 | IMAGE FORMING SYSTEM - In an image forming system for an image forming apparatus for forming an image according to the image forming system under an instruction of a terminal unit connected thereto by way of a network to instruct a formation of an image according to output data, the terminal unit sets an access information such as permitting a particular person to access the output data. The image forming apparatus compares the user information with the access information and outputs an image only when the output user conforms to the particular person. The terminal unit further changes the access information so that a second particular user other than the particular user can temporarily access to the output data and the image forming apparatus can output an image by the use of the output data also when the access information conforms to the second particular user. | 03-19-2009 |
Naoto Kuramochi, Kashiwa-Shi JP
Patent application number | Description | Published |
---|---|---|
20100248113 | CARRIER COATED WITH RESIN FOR ELECTROPHOTOGRAPHIC DEVELOPER AND ELECTROPHOTOGRAPHIC DEVELOPER USING THE CARRIER COATED WITH RESIN - A carrier coated with a resin for an electrophotographic developer in which a carrier particle surface is coated with the resin and the coating resin contains a lithium salt, and an electrophotographic developer using the carrier coated with the resin. | 09-30-2010 |
Ryuta Kuramochi, Yokohama JP
Patent application number | Description | Published |
---|---|---|
20160102487 | Biaxial Hinge and Terminal Device Using the Same - In order to provide a biaxial hinge and terminal device which ensure that a first and a second casings can open and close 360 degrees relative to each other, as well as enable a keyboard portion and rubber feet to sink relative to the upper surface of the first casing, from a predetermined opening/closing angle, the biaxial hinge comprises a biaxial hinge portion and an actuating mechanism for actuating operating mechanism(s) working on keyboard and rubber feet. Further, the actuating mechanism comprises a cam part moving in association with the movement of the biaxial hinge portion and together with opening/closing operations of the first and the second casings, and a slide part of which an end contacts with the cam part. The slide part is further provided on the attaching plate attached to the first and the second hinge shafts so as to start moving from a predetermined opening/closing angle. | 04-14-2016 |
Ryuta Kuramochi, Kanagawa JP
Patent application number | Description | Published |
---|---|---|
20130318746 | Biaxial Hinge - To provide a biaxial hinge which enables an opening/closing movement of terminal, such as notebook PC, from 0° up to 180° or more, which ensures the opening/closing movement starting from a stable stopping position available at any opening/closing angle, a second hinge shaft attached to a second casing and a second hinge shaft attached to a second casing are connected to each other via a joint member and provided so as to be rotatable relative to each other, and a selective rotation restricting device is provided between the both hinge shafts. The selective rotation restricting device is so structured that it allows the both hinge shafts to rotate, when the first casing and the second casing are in a closed state, and it restricts one of the first hinge shaft and the second hinge shaft in rotation, when the other hinge shaft rotates relative to the one hinge shaft. | 12-05-2013 |
Satoru Kuramochi, Shinjuku-Ku JP
Satoshi Kuramochi, Okazaki JP
Patent application number | Description | Published |
---|---|---|
20160072361 | VEHICLE DRIVE DEVICE - A vehicle drive device that includes a rotary electric machine; a transmission device that is disposed side by side with the rotary electric machine in an axial direction thereof; a differential gear device that has a rotation-axial center substantially parallel to that of the transmission device, and is disposed on an axis other than that of the transmission device; and an inverter device that includes a capacitor that smooths direct-current power and a conversion unit that performs direct current/alternating current conversion, and controls the rotary electric machine. | 03-10-2016 |
Taichi Kuramochi, Shizuoka JP
Patent application number | Description | Published |
---|---|---|
20100239577 | ANTI-GLYPICAN-3 ANTIBODY HAVING IMPROVED KINETICS IN PLASMA - A method of modulating the plasma half-life of anti-glypican 3 antibody, a pharmaceutical composition comprising as an active ingredient the anti-glypican 3 antibody that has a plasma half-life that has been modulated, a method of preparing the anti-glypican 3 antibody and a pharmaceutical composition comprising the anti-glypican 3 antibody as an active ingredient are provided. Disclosed is a method of modulating the plasma half-life of anti-glypican 3 antibody by modifying an amino acid residue that is exposed on the surface of the anti-glypican 3 antibody; and anti-glypican 3 antibody that has a plasma half-life that has been modulated by amino acid residue modification, a pharmaceutical composition comprising as an active ingredient the anti-glypican 3 antibody, and a method of preparing the anti-glypican 3 antibody and producing a pharmaceutical composition comprising the anti-glypican 3 antibody as an active ingredient. | 09-23-2010 |
20110076275 | Method of Modifying Isoelectric Point of Antibody Via Amino Acid Substitution in CDR - The present inventors provide methods for modifying the isoelectric point of an antibody while retaining its antigen-binding activity, comprising modifying the charge of at least one exposable amino acid residue on the surface of the complementarity determining region (CDR). The present invention also provides methods for purifying multispecific antibodies, comprising modifying isoelectric point, and methods for improving the plasma pharmacokinetics of antibodies, comprising modifying isoelectric point. The present invention further provides antibodies with a modified isoelectric point, pharmaceutical compositions comprising the antibodies as an active ingredient, and methods for producing the antibodies and compositions. | 03-31-2011 |
20110129459 | ANTI-NR10 ANTIBODY AND USE THEREOF - The present inventors successfully obtained anti-NR10 antibodies having an effective neutralizing activity against NR10. The anti-NR10 antibodies provided by the present invention are useful as, for example, pharmaceuticals for treating or preventing inflammatory diseases. | 06-02-2011 |
20110229459 | ANTI-NR10 ANTIBODY AND USE THEREOF - The present inventors successfully obtained anti-NR10 antibodies having an effective neutralizing activity against NR10. The anti-NR10 antibodies provided by the present invention are useful as, for example, pharmaceuticals for treating or preventing inflammatory diseases. | 09-22-2011 |
20120071634 | Antibody Constant Region Variant - By altering amino acid sequences, the present inventors successfully produced constant regions that can confer antibodies with particularly favorable properties for pharmaceutical agents. When used to produce antibodies, the altered constant regions produced according to the present invention significantly reduce heterogeneity. Specifically, the antibody homogeneity can be achieved by using antibody heavy chain and light chain constant regions introduced with alterations provided by the present invention. More specifically, the alterations can prevent the loss of homogeneity of antibody molecules due to disulfide bond differences in the heavy chain. Furthermore, in a preferred embodiment, the present invention can improve antibody pharmacokinetics as well as prevent the loss of homogeneity due to C-terminal deletion in antibody constant region. | 03-22-2012 |
20120121587 | ANTI-AXL ANTIBODY - An objective of the present invention is to decrease the immunogenicity of mouse-derived anti-AXL antibodies in humans by humanizing them. The present invention provides antibodies that can bind to a specific region in Anexelekto (AXL) and humanized antibodies that are produced based on such antibodies. The anti-AXL antibodies of the present invention have high antitumor activity, and are useful as agents for decreasing the AXL expression level, antitumor agents, and diagnostic agents for cancer. | 05-17-2012 |
20120238729 | Modified Antibody Constant Regions - The present inventors successfully provided constant regions capable of enhancing the agonist activity of antibodies through amino acid sequence alterations. Specifically, agonist activity was found to be enhanced in antibodies having a constant region in which amino acids of the antibody heavy chain constant region are substituted or deleted, or antibodies having a constant region in which the hinge region amino acids are substituted. Use of such antibodies as pharmaceutical formulations can provide pharmaceutical formulations with improved performance. | 09-20-2012 |
20130101581 | ANTIBODY CONSTANT REGION VARIANT - The present inventors carried out dedicated research to generate antibody constant regions with reduced Fcγ receptor-binding activity by altering amino acid sequences in the antibody constant region. As a result, the present inventors successfully identified novel constant region sequences with reduced Fcγ receptor-binding activity compared to conventional antibody constant regions. | 04-25-2013 |
20130295612 | ANTI-GLYPICAN-3 ANTIBODY HAVING IMPROVED KINETICS IN PLASMA - A method of modulating the plasma half-life of anti-glypican 3 antibody, a pharmaceutical composition comprising as an active ingredient the anti-glypican 3 antibody that has a plasma half-life that has been modulated, a method of preparing the anti-glypican 3 antibody and a pharmaceutical composition comprising the anti-glypican 3 antibody as an active ingredient are provided. Disclosed is a method of modulating the plasma half-life of anti-glypican 3 antibody by modifying an amino acid residue that is exposed on the surface of the anti-glypican 3 antibody; and anti-glypican 3 antibody that has a plasma half-life that has been modulated by amino acid residue modification, a pharmaceutical composition comprising as an active ingredient the anti-glypican 3 antibody, and a method of preparing the anti-glypican 3 antibody and producing a pharmaceutical composition comprising the anti-glypican 3 antibody as an active ingredient. | 11-07-2013 |
20140039165 | ANTI-NR10 ANTIBODY AND USE THEREOF - The present inventors successfully obtained anti-NR | 02-06-2014 |
20140093496 | Fc-gamma-RIIb-SPECIFIC Fc ANTIBODY - An objective of the present invention is to provide a polypeptide containing an Fc region having maintained or decreased binding activities towards both allotypes of FcγRIIa, types H and R, and having enhanced FcγRIIb-binding activity in comparison with a parent polypeptide; a pharmaceutical composition containing the polypeptide; an agent for treating or preventing immunological inflammatory diseases that includes the pharmaceutical composition; a production method thereof; and a method for maintaining or decreasing binding activities towards both allotypes of FcγRIIa and enhancing the FcγRIIb-binding activity. Specifically, it is found that a polypeptide containing an antibody Fc region that has an alteration of substituting Pro at position 238 (EU numbering) with Asp or Leu at position 328 (EU numbering) with Glu enhances FcγRIIb-binding activity, and maintains or decreases binding activities towards both allotypes of FcγRIIa, types H and R. It is also found that a polypeptide containing an antibody Fc region that contains an alteration of substituting Pro at position 238 (EU numbering) with Asp and several other alterations, enhances FcγRIIb-binding activity, and maintains or decreases binding activities towards both allotypes of FcγRIIa, types H and R. | 04-03-2014 |
20140105889 | METHOD FOR ALTERING PLASMA RETENTION AND IMMUNOGENICITY OF ANTIGEN-BINDING MOLECULE - The present invention demonstrated that the modification of the Fc region of an antigen-binding molecule into an Fc region that does not form in a neutral pH range a heterotetramer complex containing two molecules of FcRn and an active Fcγ receptor improved the pharmacokinetics of the antigen-binding molecule and reduced the immune response to the antigen-binding molecule. The present invention also revealed methods for producing antigen-binding molecules having the properties described above, and successfully demonstrated that pharmaceutical compositions containing as an active ingredient such an antigen-binding molecule or an antigen-binding molecule produced by a production method of the present invention have excellent features over conventional antigen-binding molecules in that when administered, they exhibit improved pharmacokinetics and reduced in vivo immune response. | 04-17-2014 |
20140112914 | CYTOTOXICITY-INDUCING THERAPEUTIC AGENT - By replacing the antigen-binding domain, the present inventors discovered novel polypeptide complexes that retain BiTE's strong anti-tumor activity and excellent safety properties, as well as have long half-life in blood and can damage various different target cells. | 04-24-2014 |
20140199294 | HETERODIMERIZED POLYPEPTIDE - The present inventors produced a heterodimerized polypeptide having an Fc region formed from two polypeptides with different amino acid sequences (a first polypeptide and a second polypeptide), and succeeded in producing a heterodimerized polypeptide containing an Fc region with improved Fc region function compared to that of a homodimer in which the Fc region is composed of only the first polypeptide or only the second polypeptide by conventional technology. | 07-17-2014 |
20140363428 | THERAPEUTIC ANTIGEN-BINDING MOLECULE WITH A FcRn-BINDING DOMAIN THAT PROMOTES ANTIGEN CLEARANCE - The present invention provides: a modified FcRn-binding domain having an enhanced affinity for the Fc Receptor neonatal (FcRn) at neutral pH; an antigen-binding molecule comprising said FcRn-binding domain, which has low immunogenicity, high stability and form only a few aggregates; a modified antigen-binding molecule having an increased FcRn-binding activity at neutral or acidic pH without an increased binding activity at neutral pH for a pre-existing anti-drug antibody; use of the antigen-binding molecules for improving antigen-binding molecule-mediated antigen uptake into cells; use of the antigen-binding molecules for reducing the plasma concentration of a specific antigen; use of the modified FcRn-binding domain for increasing the total number of antigens to which a single antigen-binding molecule can bind before its degradation; use of the modified FcRn-binding domain for improving pharmacokinetics of an antigen-binding molecule; methods for decreasing the binding activity for a pre-existing anti-drug antibody; and methods for producing said antigen-binding molecules. | 12-11-2014 |
20140370020 | ANTIGEN-BINDING MOLECULE HAVING REGULATED CONJUGATION BETWEEN HEAVY-CHAIN AND LIGHT-CHAIN - It was found that association between CH1 and CL can be suppressed by substituting amino acids that exist on the interface between CH 1 and CL with electrically-charged amino acids, and that formation of heterogeneous molecules is enabled more efficiently than by introducing knobs into holes mutations into CH3 domain. | 12-18-2014 |
20150110793 | Humanized Anti-Epiregulin Antibody, and Cancer Therapeutic Agent Comprising Said Antibody as Active Ingredient - The inventors successfully produced anti-Epiregulin antibodies showing cross-species reactivity between cynomolgus monkey (non-human animals) and human, anti-Epiregulin antibodies with suppressed chemical degradation, anti-Epiregulin antibodies with lowered isoelectric point, anti-Epiregulin antibodies with increased thermal denaturation midpoint temperature, and anti-Epiregulin antibodies with reduced amount of aggregate by performing appropriate amino acid residue substitutions in the variable-region sequences of the humanized EP27 antibody which inhibits growth of cancer cells by exhibiting cytotoxic activity and neutralizing activity against human Epiregulin-expressing cancer cells. | 04-23-2015 |
20150175704 | ANTI-NR10 ANTIBODY AND USE THEREOF - The present inventors successfully obtained anti-NR10 antibodies having an effective neutralizing activity against NR10. The anti-NR10 antibodies provided by the present invention are useful as, for example, pharmaceuticals for treating or preventing inflammatory diseases. | 06-25-2015 |
20150210763 | MODIFIED Fc REGION OF ANTIBODY - Polypeptides with improved stability as compared to that of a parent polypeptide were successfully obtained by modifying at least one amino acid in a loop region of the antibody Fc region. Furthermore, by combining multiple amino acid modifications in the loop region, polypeptides with maintained or enhanced FcγR-binding activity as well as improved thermal stability, polypeptides with decreased FcγR-binding activity as well as improved thermal stability, and polypeptides with not only improved thermal stability and adjusted FcγR-binding activity but also decreased aggregate content, as compared to those of a parent polypeptide, were successfully obtained. | 07-30-2015 |
20150274809 | ANTIBODY CONSTANT REGION VARIANT - By altering amino acid sequences, the present inventors successfully produced constant regions that can confer antibodies with particularly favorable properties for pharmaceutical agents. When used to produce antibodies, the altered constant regions produced according to the present invention significantly reduce heterogeneity. Specifically, the antibody homogeneity can be achieved by using antibody heavy chain and light chain constant regions introduced with alterations provided by the present invention. More specifically, the alterations can prevent the loss of homogeneity of antibody molecules due to disulfide bond differences in the heavy chain. Furthermore, in a preferred embodiment, the present invention can improve antibody pharmacokinetics as well as prevent the loss of homogeneity due to C-terminal deletion in antibody constant region. | 10-01-2015 |
20150284465 | Method of Modifying Isoelectric Point of Antibody Via Amino Acid Substitution in CDR - The present inventors provide methods for modifying the isoelectric point of an antibody while retaining its antigen-binding activity, comprising modifying the charge of at least one exposable amino acid residue on the surface of the complementarity determining region (CDR). The present invention also provides methods for purifying multispecific antibodies, comprising modifying isoelectric point, and methods for improving the plasma pharmacokinetics of antibodies, comprising modifying isoelectric point. The present invention further provides antibodies with a modified isoelectric point, pharmaceutical compositions comprising the antibodies as an active ingredient, and methods for producing the antibodies and compositions. | 10-08-2015 |
Takahiro Kuramochi, Chuo-Ku JP
Patent application number | Description | Published |
---|---|---|
20090270365 | BENZAMIDE DERIVATIVE OR SALT THEREOF - There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the like. | 10-29-2009 |
Takashi Kuramochi, Gunma JP
Patent application number | Description | Published |
---|---|---|
20110309408 | SEMICONDUCTOR DEVICE AND METHOD OF PRODUCING SAME - A semiconductor device provided with: an island and an island which are separated from each other; leads which approach the islands at one end; a control element which is attached to the island and is connected to a lead through a thin metal wire; and a switching element which is attached to the island and is connected to the lead through a metal wire. Further, the thin metal wire and the thin metal wire are arranged so as to the intersect. | 12-22-2011 |
Takeharu Kuramochi, Yokohama-Shi JP
Patent application number | Description | Published |
---|---|---|
20110229801 | MANUFACTURE OF FUEL CELL - A fuel cell is manufactured using a polymer electrolyte membrane ( | 09-22-2011 |
20110229802 | MANUFACTURE OF FUEL CELL - A fuel cell is manufactured using a polymer electrolyte membrane ( | 09-22-2011 |
20110236801 | FUEL CELL AND PRODUCTION OF FUEL CELL STACK - Separators ( | 09-29-2011 |
Toshikatsu Kuramochi, Wako-Shi JP
Patent application number | Description | Published |
---|---|---|
20150175199 | VEHICLE STEERING DEVICE - A mode setting unit of ECU controls a turning angle so as to be a turning angle in accordance with a steering angle detected by a steering angle sensor. When a vehicle is started, the mode setting unit controls an angle ratio so as to be an angle ratio that is equal to or smaller than a ratio of the turning angle to the steering angle (mechanical angle ratio) when a steering wheel and a turning mechanism are connected by a clutch mechanism. | 06-25-2015 |
20150203147 | VEHICLE STEERING DEVICE - A vehicle steering device includes a steering wheel operated by a driver to steer a vehicle; a steering reaction force motor that applies a reaction force to the steering wheel; a turning device that turns turning wheels of the vehicle by a turning motor; a clutch mechanism that mechanically connects and disconnects the steering wheel with and from the turning device; a control device that provides control so that a turning angle is based on a steering angle of the steering wheel; and a temperature sensor that measures a temperature. The vehicle steering device mechanically couples the steering wheel and the turning device and activates the steering wheel and the turning device if the temperature is a predetermined value or lower. | 07-23-2015 |
20150246683 | VEHICLE STEERING DEVICE - A vehicle steering device includes a steering reaction force generating device having a steering reaction force motor; a steering device having a steering motor; a clutch device having an electromagnetic solenoid that sets the steering reaction force generating device and the steering device in a mechanically engaged or disengaged state; a current integrated value acquisition unit that obtains an integrated value of a current of one of the steering reaction force and steering motors; an overload state determination unit that determines whether or not the one motor is in an overload state based on the integrated value of the current supplied to the one motor, obtained by the current integrated value acquisition unit; and a drive control unit that controls driving of the electromagnetic solenoid to set the clutch device in an engaged state when the overload state determination unit determines that the one motor is in an overload state. | 09-03-2015 |
20150321692 | VEHICLE STEERING APPARATUS - A vehicle steering apparatus includes a steering reaction force generating device including a steering reaction force motor, a turning device including a turning motor, a clutch device including an electromagnetic solenoid configured to mechanically engage and disengage the steering reaction force generating device and the turning device, a turning motor temperature sensor configured to detect a motor temperature value of the turning motor, a current integrated value acquiring unit configured to acquire a current integrated value of the turning motor, an abnormality diagnostic unit configured to diagnose whether the turning motor temperature sensor is normal, and a drive control unit configured to control the drive of the electromagnetic solenoid on the basis of the current integrated value of the turning motor acquired by the current integrated value acquiring unit if the abnormality diagnostic unit diagnoses the turning motor temperature sensor as being in an abnormal state. | 11-12-2015 |
Toshiyuki Kuramochi, Nagano-Shi JP
Patent application number | Description | Published |
---|---|---|
20090001133 | ELECTRONIC COMPONENT MOUNTING DEVICE AND METHOD OF MANUFACTURING ELECTRONIC DEVICE - An electronic component mounting device according to the invention includes a bonding head for holding and pressure bonding an electronic component to a mounting substrate, a local stage provided with a support surface formed in an area which is almost equal to or slightly larger than that of a mounting surface of the electronic component and serving to support a pressure bonding force from an antimounting surface of the mounting substrate through the support surface, a length measuring mechanism for measuring a distance between the bonding head and the mounting substrate, thereby calculating a virtual plane in a predetermined mounting position on the mounting substrate, and a tilting and moving mechanism for tilting and moving the bonding head and the local stage, thereby causing a normal of the virtual plane in the mounting position to be coincident with an action line of the pressure bonding force, and the pressure bonding is carried out along the normal. | 01-01-2009 |
20090159316 | WIRING SUBSTRATE AND METHOD OF MANUFACTURING THE SAME - A wiring substrate is provided. The wiring substrate includes: a core layer in which a gap is formed; and a lamination layer which includes an insulating layer and a wiring layer and which is formed on at least one surface of the core layer. The lamination layer has a thermal expansion coefficient different from that of the core layer. A plurality of mounting regions on which an electronic component is to be mounted are provided on the lamination layer to be spaced from each other. The gap in the core layer is filled with an insulating member having the same material as the insulating layer and surrounds each of the plurality of mounting regions or each of mounting region groups including one or more of the mounting regions. | 06-25-2009 |
Yasuhide Kuramochi, Miyagi JP
Patent application number | Description | Published |
---|---|---|
20100109674 | DEVICE, TEST APPARATUS AND TEST METHOD - Provided is a test apparatus that tests a device under test. The device under test includes: a circuit under test; and a switching section that that connects an internal terminal being tested, from among one or more internal terminals of the circuit under test, to external terminals connected to the test apparatus. The test apparatus includes: a measuring section that controls a relay section, which provides a connection or a disconnect between two of the external terminals such that a transmission characteristic of the relay section in a connected state serves as a basis for calculating the transmission characteristic between each external terminal and each internal terminal of the circuit under test, to be in a connected state and measures the transmission characteristic of the relay section via the two external terminals; and a compensating section that compensates a signal to be supplied to the circuit under test via an external terminal and the switching section and/or a signal acquired from the circuit under test via the switching section and an external terminal, based on the measured transmission characteristic of the relay section. | 05-06-2010 |
20100156689 | A-D CONVERT APPARATUS, D-A CONVERT APPARATUS AND ADJUSTMENT METHOD - An A/D conversion device including a first A/D conversion section and a second A/D conversion section that each include a D/A converter that has a plurality of bit capacitors corresponding to bits of input data, a comparing section that compares a reference voltage with a difference voltage obtained by subtracting an analog input voltage from an output voltage of the D/A converter, and a control section that detects a data value of the input data at which the difference voltage is substantially the same as the reference voltage and outputs the data value as digital data according to the input voltage, and an adjusting section that serially connects the bit capacitors of the D/A converter of the first A/D conversion section and the bit capacitors of the D/A converter of the second A/D conversion section that correspond to the same bits, and adjusts a capacity of at least one of the bit capacitors so that a voltage between the two bit capacitors approaches a middle point of voltages of the two bit capacitors. | 06-24-2010 |
Yasuhide Kuramochi, Gunma JP
Patent application number | Description | Published |
---|---|---|
20110133751 | SIGNAL GENERATING APPARATUS AND TEST APPARATUS - Provided is a signal generating apparatus comprising a DA converter that outputs an output signal corresponding to input data supplied thereto; a sample/hold unit that is provided between the DA converter and an output end of the signal generating apparatus, and that samples an output voltage of the DA converter and holds the sampled output voltage; a comparing section that compares (i) a level of a signal output from an analog circuit that propagates the output signal to output a signal corresponding to the input data to (ii) a level of the signal output by the DA converter; and a control section that, during a holding period, (iii) provides the DA converter with comparison data instead of the input data to cause the DA converter to output a comparison voltage corresponding to the comparison data, (iv) causes the comparing section to compare a voltage of the signal output by the analog circuit to the comparison voltage, and (v) adjusts the output voltage of the DA converter according to the input data based on a comparison result of the comparing section. | 06-09-2011 |
20110140938 | SIGNAL GENERATING APPARATUS AND TEST APPARATUS - Provided is a signal generating apparatus comprising a DA converter that outputs an output signal corresponding to input data supplied thereto; a sample/hold unit that is provided between the DA converter and an output end of the signal generating apparatus, and that samples an output voltage of the DA converter and holds the sampled output voltage; a comparing section that compares (i) a level of a signal output from an analog circuit that propagates the output signal to output a signal corresponding to the input data to (ii) a level of the signal output by the DA converter; and a control section that, during a holding period, (iii) provides the DA converter with comparison data instead of the input data to cause the DA converter to output a comparison voltage corresponding to the comparison data, (iv) causes the comparing section to compare a voltage of the signal output by the analog circuit to the comparison voltage, and (v) adjusts the output voltage of the DA converter based on a comparison result of the comparing section. | 06-16-2011 |
20110148499 | SIGNAL GENERATING APPARATUS AND TEST APPARATUS - Provided is a signal generating apparatus that outputs from an output end thereof an output voltage corresponding to input data supplied thereto, comprising: a DA converter that outputs a voltage corresponding to data supplied thereto; a capacitor section that is provided between the output end and a standard potential; a transmission switch that provides a connection or a disconnect between a voltage generating end of the DA converter and the output end; and a control section that causes the DA converter to charge the capacitor section with a voltage corresponding to the input data by repeatedly connecting and disconnecting the transmission switch, thereby causing the voltage of the capacitor section to gradually approach the output voltage corresponding to the input data. | 06-23-2011 |
20110148680 | DIGITAL-ANALOG CONVERTING APPARATUS AND TEST APPARATUS - Provided is a DA conversion apparatus comprising a capacitor array DA converter that outputs to an output line an output voltage corresponding to a digital value input thereto; and a load changing section that changes a size of a load capacitance connected to the output line. The load changing section may set gain of the DA conversion apparatus with the size of the load capacitance connected to the output line being a constant capacitance unaffected by the digital value. The load changing section may include a load capacitor connected between the output line and a standard potential; a load-side switch connected in series with the load capacitor between the output line and the standard potential; and a load capacitance control section that controls the load-side switch. | 06-23-2011 |
20110169674 | A-D convert apparatus and control method - Provided is an AD conversion apparatus including: a differential amplifier that generates a differential input voltage according to an analog input signal; a differential DA converter of a charge redistribution type, which outputs a differential output voltage resulting from subtracting the differential input voltage from a differential comparison voltage that is in accordance with comparison data; a comparator that compares a positive output voltage and a negative output voltage in the differential output voltage; a control section that identifies the comparison data at which the differential output voltage becomes substantially 0 based on a comparison result of the comparator, and outputs the identified comparison data as output data; and a setting section that sets at least one of a common potential of the differential amplifier and a common potential of the differential DA converter, according to a targeted value of a common potential of the comparator | 07-14-2011 |
20110181298 | MEASUREMENT APPARATUS AND TEST APPARATUS - Provided is a measurement apparatus that measures a signal under measurement input thereto, comprising a plurality of signal measurement circuits that measure a level of a signal input thereto, according to a sampling clock provided thereto; a noise measuring section that measures a noise component propagated from a first signal measurement circuit to a second signal measurement circuit, among the plurality of signal measurement circuits, based on a measurement result output by the second signal measurement circuit; and a clock supplying section that, when the signal under measurement is being measured, supplies the first signal measurement circuit and the second signal measurement circuit with sampling clocks having the same period and that, when the noise component is being measured, supplies the first signal measurement circuit and the second signal measurement circuit with sampling clocks having different periods. | 07-28-2011 |
20110193733 | OUTPUT APPARATUS AND TEST APPARATUS - Provided is an output apparatus comprising a plurality of current sources; a plurality of holding sections that correspond respectively to the current sources and that each hold a designated voltage that designates a current flowing through the corresponding current source; a setting DAC that sequentially generates the designated voltage to be held by each holding section; and a supply section that sequentially switches a supply of the designated voltage generated by the setting DAC among corresponding holding sections. | 08-11-2011 |
20120176143 | SAMPLING APPARATUS AND TEST APPARATUS - A sampling apparatus that converts an analog target signal in which the same waveform repeats into a digital value by sampling the target signal at each of a plurality of phases, and outputs the digital value. The sampling apparatus comprises a designating section that sequentially designates bits in the digital value as target bits, beginning with the most significant bits; a generating section that, for each designated target bit, generates a threshold value for determining a value of the target bit based on a determined value of a bit that is higher-order than the target bit in the digital value at each of the phases; and a converting section that, for each designated target bit, determines the value of the target bit in the digital value at each phase by comparing the target signal to an analog comparison signal corresponding to the threshold value at each phase. | 07-12-2012 |
20120262321 | ANALOG TO DIGITAL CONVERTER AND DIGITAL TO ANALOG CONVERTER - To decrease the burden of digital processing, provided is an AD conversion apparatus comprising a pattern generating section that, for each target bit specified one bit at a time moving downward in the output data, generates a pattern signal having a pulse width or number of pulses corresponding to a weighting of the target bit; an integrating section that integrates the pattern signals according to a judgment value for judging a value of the target bit each time a pattern signal is generated, and outputs a reference signal obtained by accumulating the integrated value of each pattern signal; a comparing section that, each time generation of a pattern signal is finished, compares the input signal to the reference signal; and an output section that outputs the output data to have values corresponding to the comparison results obtained after each generation of a pattern signal corresponding to a bit is finished. | 10-18-2012 |
20130141266 | ANALOG TO DIGITAL CONVERTER AND DIGITAL TO ANALOG CONVERTER - To decrease the burden of digital processing, provided is an AD conversion apparatus comprising a pattern generating section that, for each target bit specified one bit at a time moving downward in the output data, generates a pattern signal having a pulse width or number of pulses corresponding to a weighting of the target bit; an integrating section that integrates the pattern signals according to a judgment value for judging a value of the target bit each time a pattern signal is generated, and outputs a reference signal obtained by accumulating the integrated value of each pattern signal; a comparing section that, each time generation of a pattern signal is finished, compares the input signal to the reference signal; and an output section that outputs the output data to have values corresponding to the comparison results obtained after each generation of a pattern signal corresponding to a bit is finished. | 06-06-2013 |
20140028326 | DA-CONVERTER AND TEST APPARATUS - A DA conversion apparatus comprising a DA converting section that includes a plurality of analog elements; and a control section that generates first shift data and second shift data by shifting the input digital data by respective shift amounts of M bits and N bits, and controls the analog elements based on the first shift data and the second shift data, wherein the control section changes a control state for each of the common analog elements according to the bit shift amounts M and N in the control section, between at least two control states including a control state in which the common analog element is controlled according to higher-order bits of the first shift data and a control state in which the common analog element is controlled according higher-order bits of the second shift data. | 01-30-2014 |
Yoshimi Kuramochi, Mishima-Shi JP
Patent application number | Description | Published |
---|---|---|
20090003857 | RECORDING MATERIAL DETERMINATION APPARATUS ANDIMAGE FORMING APPARATUS - A recording material determination apparatus includes a first detection unit configured to detect a characteristic corresponding to a surface condition of a recording material based on a captured image of a surface of the recording material, a second detection unit configured to detect a characteristic corresponding to a grammage of the recording material based on an ultrasonic wave detected via the recording material by irradiating the recording material with an ultrasonic wave, and a conveyance unit configured to convey the recording material. The first detection unit and the second detection unit are located opposite each other with respect to the conveyance unit. | 01-01-2009 |
20120002988 | RECORDING MATERIAL DETERMINATION APPARATUS AND IMAGE FORMING APPARATUS - A recording material determination apparatus includes a first detection unit configured to detect a characteristic corresponding to a surface condition of a recording material based on a captured image of a surface of the recording material, a second detection unit configured to detect a characteristic corresponding to a grammage of the recording material based on an ultrasonic wave detected via the recording material by irradiating the recording material with an ultrasonic wave, and a conveyance unit configured to convey the recording material. The first detection unit and the second detection unit are located opposite each other with respect to the conveyance unit. | 01-05-2012 |
20130148990 | RECORDING MATERIAL DETERMINATION APPARATUS ANDIMAGE FORMING APPARATUS - A recording material determination apparatus includes a first detection unit configured to detect a characteristic corresponding to a surface condition of a recording material based on a captured image of a surface of the recording material, a second detection unit configured to detect a characteristic corresponding to a grammage of the recording material based on an ultrasonic wave detected via the recording material by irradiating the recording material with an ultrasonic wave, and a conveyance unit configured to convey the recording material. The first detection unit and the second detection unit are located opposite each other with respect to the conveyance unit. | 06-13-2013 |
Yuichi Kuramochi, Hitachinaka JP
Patent application number | Description | Published |
---|---|---|
20080236964 | Electric Braking Apparatus - An electric braking apparatus including a motor for pressing brake pads on disks, a metal housing for housing the motor, a positive-polarity power line for transmitting power from a battery to the electric motor, a negative-polarity ground line for connecting the electric motor to the ground of a vehicle, and a conductor for electrically connecting the metal housing to the negative polarity of battery or the negative-polarity of an inverter. | 10-02-2008 |
Yuichi Kuramochi, Isesaki-Shi Gunma JP
Patent application number | Description | Published |
---|---|---|
20160033559 | OVERCURRENT DETECTING DEVICE AND OVERCURRENT DETECTING METHOD - The present invention relates to an overcurrent detecting device and an overcurrent detecting method each of which detects an overcurrent upstream of an inverter circuit in a drive control device for an electric motor. The overcurrent is detected without providing a shunt resistor in the upstream of the inverter circuit, and miniaturization of a circuit substrate is achieved. The overcurrent detecting device calculates a current value of a power supply line from each phase current supplied to the electric motor and a power supply voltage of the inverter circuit, and detects an overcurrent, based on a current value determined from a drop voltage value by an electronic part connected to the power supply line and the current value of the power supply line. | 02-04-2016 |
Yuichi Kuramochi, Isesaki-Shi JP
Patent application number | Description | Published |
---|---|---|
20110231053 | Vehicle Control Device Capable of Controller Area Network Communication and Diagnostic Method Therefor - The present invention relates to a vehicle control device that is communicably connected to other control devices so that controller area network (CAN) communication can be performed through a communication bus and a diagnostic method thereof. The vehicle control device includes a CAN data transmission unit that can generate and transmit CAN data, a transmission stop unit that stops transmission of the CAN data transmitted from the CAN data transmission unit to the communication bus when a transmission stop signal is inputted, an abnormality detection unit that outputs the transmission stop signal to the transmission stop unit when detecting an abnormality in the vehicle control device, and a diagnostic unit that causes the abnormality detection unit to output the transmission stop signal regardless of the detection of abnormality, causes the CAN data transmission unit to transmit the CAN data, and diagnoses a transmission stop function that stops the transmission of the CAN data to the communication bus on the basis of a result of comparison between the transmitted CAN data and data on the communication bus. | 09-22-2011 |
20120068546 | POWER SUPPLY UNIT AND ITS CONTROL DEVICE - A control device is provided that includes a power supply unit. First and second MOSFETs are serially connected to a sub power supply line in the power supply unit by connecting their respective drains to one another. Third and fourth MOSFETs are serially connected to a sub power supply in a control unit by connecting their respective drains to one another. By controlling these MOSFETs, power of the sub power supply is supplied to a load. The drain voltage of each MOSFET, and the voltage between the second MOSFET and the third MOSFET are monitored to determine a short-circuit fault and an open-circuit fault of the MOSFET, and a ground fault in the sub power supply line between the power supply unit and the control unit. | 03-22-2012 |
20140202145 | Control Device and Control Method of Electric Booster - A control device and a control method of an electric booster include an assist function by an electrical actuator. An input piston of the electric booster moves along an axial direction within the booster piston in response to an operation of a brake pedal. During a brake operation, the control device controls an electric motor to integrally move the input piston and the booster piston while retaining a length of a gap between the input piston and the booster piston. In addition, when starting an internal-combustion engine, the control device performs a control of shortening the length of the gap to prepare for a decrease in power supply voltage of the electric motor. Therefore, a force in a return direction applied to the input piston from the booster piston in association with a power supply drop is suppressed, and causing a driver to feel a sense of discomfort is suppressed. | 07-24-2014 |
Yuichi Kuramochi, Aichi JP
Patent application number | Description | Published |
---|---|---|
20130015951 | LOCK DEVICE FOR POWER SUPPLYING PLUGAANM KURAMOCHI; YuichiAACI AichiAACO JPAAGP KURAMOCHI; Yuichi Aichi JPAANM KATAGIRI; ToshiharuAACI AichiAACO JPAAGP KATAGIRI; Toshiharu Aichi JPAANM KAHARA; KeijiAACI AichiAACO JPAAGP KAHARA; Keiji Aichi JPAANM KURUMIZAWA; NaotoAACI AichiAACO JPAAGP KURUMIZAWA; Naoto Aichi JPAANM HIRASHITA; TakahiroAACI AichiAACO JPAAGP HIRASHITA; Takahiro Aichi JP - A lock device for a power supplying plug arranged in a vehicle that performs wireless communication with an electronic key. The lock device includes a charge ECU that restricts unauthorized removal of the power supplying plug from an inlet of the vehicle. The vehicle includes antennas that transmit a wireless signal. A first one of the antennas relates to permission for removal of the power supplying plug. A second one of the antennas relates to unlocking or permission for unlocking of a door. A charge ECU stops transmitting the wireless signal from the first antenna when the vehicle is parked and the second antenna transmits the wireless signal. The charge ECU stops the transmission of the wireless signal related to the unlocking of the door when the wireless signal related to removal of the power supplying plug is transmitted. | 01-17-2013 |
Yuji Kuramochi, Niwa-Gun JP
Patent application number | Description | Published |
---|---|---|
20110243680 | METHOD OF BORING WORK BY 5-AXIS MACHINING DOUBLE-HOUSING MACHINE TOOL AND 5-AXIS MACHINING DOUBLE-HOUSING MACHINE TOOL - A slip ring is accommodated in a ram | 10-06-2011 |
Yusuke Kuramochi, Tokorozawa-Shi JP
Patent application number | Description | Published |
---|---|---|
20120041203 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM - A metal complex containing a nitrogen-containing aromatic ring ligand which has a dendritic molecular chain, and a copper(I) ion or a silver(I) ion. For example, the metal complex which is represented by compositional formula (8): | 02-16-2012 |
20120211706 | POLYDENTATE LIGAND METAL COMPLEX - The present invention provides a metal complex that has excellent durability, and a device and the like having excellent durability that uses such a metal complex. Specifically, the present invention provides a metal complex comprising (a) a polydentate ligand having denticity of five or more that includes a heteroaromatic ring which contains two or more atoms selected from the group consisting of a nitrogen atom, an oxygen atom, and a sulfur atom, and (b) an ion of a metal selected from the group consisting of cerium, praseodymium, ytterbium, and lutetium; a composition comprising the metal complex and a charge transport material; an organic thin film obtained by using the metal complex or composition; and a device obtained by using the metal complex, composition, or organic thin film. | 08-23-2012 |
20130001472 | THIN FILM AND COMPOUND USED IN THE SAME - To provide a novel material exhibiting excellent light-emitting characteristics using a heavy metal element having relatively abundant reserve. | 01-03-2013 |