Patent application number | Description | Published |
20120225851 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES - The present invention relates to a chemotherapeutic cancer treatment in which compounds of Formula Ia′, Ib′, Ic′, or II′ (referred to as a group as BH3Is) are administered to a mammal for the treatment of B-cell Lymphoma or other hematopoietic cancers, including diseases associated with MCL-1. In another aspect, the invention provides a method for treating particular types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more compounds selected from the group consisting of compounds or Formula Ia, Ib, Ic, or II in combination with other therapies, for example, a class of therapeutics known as 26S proteosome inhibitors, such as, for example, Bortezomib. In another aspect the present invention relates to autoimmune treatment with pharmaceutical compositions comprising one or more compounds of Formula Ia′, Ib′, Ic′, or II′. In another aspect, this invention relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease. | 09-06-2012 |
20140221387 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES - The present invention relates to a compositions for and methods of cancer treatment in which compounds of Formula I or Formula II. In some aspects, the treatment of B-cell Lymphoma or other hematopoietic cancers is encompassed. In other aspects, the invention provides methods for treating particular types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more compounds of Formula I or Formula II. Combination therapy with, for example, a class of therapeutics known as 26S proteasome inhibitors, for example, Bortezomib, are also included. In another aspect the present invention relates to autoimmune treatment with compounds of Formula I or Formula II. In another aspect, this invention relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease. | 08-07-2014 |
20150216862 | 2,2'-BIPHENAZINE COMPOUNDS AND METHODS USEFUL FOR TREATING DISEASES - The invention relates to a chemotherapeutic cancer treatment in which compounds (BH3Is) are administered to a mammal to treat B-cell Lymphoma or other hematopoietic cancers, including diseases associated with MCL-1. The invention also provides a method for treating types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more disclosed compounds in combination with other therapes, for example, 26S proteasome inhibitors, such as, for example, Bortezomib. The invention also relates to autoimmune treatment with pharmaceutical compositions comprising one or more disclosed compounds. The invention also relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease. | 08-06-2015 |
20150352097 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES - The present invention relates to a compositions for and methods of cancer treatment in which compounds of Formula I or Formula II. In some aspects, the treatment of B-cell Lymphoma or other hematopoietic cancers is encompassed. In other aspects, the invention provides methods for treating particular types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more compounds of Formula I or Formula II. Combination therapy with, for example, a class of therapeutics known as 26S proteasome inhibitors, for example, Bortezomib, are also included. In another aspect the present invention relates to autoimmune treatment with compounds of Formula I or Formula II. In another aspect, this invention relates to methods for identifying compounds, for example, compounds of the BH3 mimic class, that have unique in vitro properties that predict in vivo efficacy against B-cell lymphoma tumors and other cancers as well as autoimmune disease. | 12-10-2015 |
Patent application number | Description | Published |
20130344852 | DELIVERING TARGETED MOBILE MESSAGES TO WIRELESS DATA NETWORK DEVICES BASED ON THEIR PROXIMITY TO KNOWN WIRELESS DATA COMMUNICATION NETWORKS - A network access controller of an apparatus in an example interacts with a proximity server to create an association between a mobile number and a media access control address of a wireless data network device. | 12-26-2013 |
20140100953 | Delivering Mobile Messages to Wireless Mobile Devices Based on Current Delivery Preference and Network Capabilities to Improve User Experience - A mobile messaging server of in an example interacts with a wireless communication data network, a device database, a campaign content database, a device preference database, and operator's network requirement database to deliver one or more of images, bar codes, videos and/or simple plain text via a pushed mobile message to a mobile device identified by a mobile number for mobile messaging communication, for example, to meet a desirable, beneficial, good, and/or best possible user experience, for example, based on mobile device capabilities and operator's network requirements at current point in time based on real time capabilities detection. | 04-10-2014 |
20140101252 | Mobile Message Sharing through Employment of Social Media Platform - A mobile messaging server of an apparatus in an example interacts with a social media platform to cause the social media platform to share, with a social network of friends of a user, a mobile message that is received by the user and comprises one or more of images, bar codes, videos, and/or simple plain text. | 04-10-2014 |
20140342761 | Method and system for delivering optimal rich media content using mobile messaging - The invention consists of a method and system for delivering optimal rich media content to a mobile device using one of multiple messaging channels. The invention includes dynamically detecting the capabilities of the mobile device and the wireless network that the mobile device is using, and then delivering an optimal choice among multiple variations of a set of rich media content. The variations in the set of rich media content may be composed statically or generated dynamically. The rich media content can be delivered via SMS, MMS or mobile application push notification. | 11-20-2014 |
20140351348 | Method and system for sharing rich media content from mobile messaging to social media networks - The invention consists of a method and system for delivering rich media content to a mobile device via mobile messaging and then distributing that rich media content to a social media network. The invention includes an easy method for a user that receives rich media content via mobile messaging to initiate sharing the same content with other users on a social media network. The invention includes a messaging system that adapts a set of rich media content to the unique constraints of mobile messaging and to the unique constraints of specific social media networks. | 11-27-2014 |
Patent application number | Description | Published |
20130210776 | COMPOSITION FOR THE TREATMENT OF SUPERFICIAL LESIONS - The invention relates to a composition for the treatment of superficial lesions, in particular skin lesions, mucous membrane lesions and/or nail lesions, an applicator comprising such a composition and the use of such a composition. The composition comprises an effective amount of trichloroacetic acid, at least one thickener, and at a physiologically acceptable solvent. And is effective against a plethora of superficial lesions selected from the group consisting of viral warts, verrucae, water warts (molluscum contagiosum), corns and calluses, and skin hyperpigmentation: age spots, solar lentigo, senial lentigo, acne, keratosis pilaris, actinic keratosis, mouth ulcers (canker sores), cold sores, ingrown toenails, onychomycosis, eyelid xanthelasma. | 08-15-2013 |
Patent application number | Description | Published |
20130337838 | LOCAL CONTENT RECOMMENDATIONS - A method is provided for offering content recommendations to a mobile station based on a current location of the mobile station. Records of one or more other mobile stations within a distance of the location at a set time frame can be identified. In association with the location of the other mobile station, identification of the time at which that other mobile station was at the location can be recorded. For each identified record of another mobile station, a search query or a result is then identified. In association with the location of the other mobile station, identifications of the search and/or result resident on that other mobile station can be recorded. The response to an inquiry from the mobile station is a recommendation that includes information about the identified search query and/or result resident on one or more of the other mobile stations. | 12-19-2013 |
20140066097 | IMPENDING HAZARD ALERT - A mobile device identifies whether potentially distracting applications are running on the mobile device as well as the activity of the user, via at least one sensor on the mobile device. If it is determined that at least one potentially distracting application is running and the user is engaged in an activity that may become dangerous due to use of the at least one potentially distracting application, a warning is provided on a user output of the mobile device when the mobile device is within a predetermined time and/or distance of an identified hazard. | 03-06-2014 |
20140235223 | CONCIERGE - Providing a contextual reminder to a mobile station includes determining a locus of the mobile station based on the position of the mobile station in both time and space. A first entry is read, where the first entry can be at least a task or an event. Both tasks and events can include a time, a date, and/or a location. The locus and the first entry can be compared to determine if the contextual reminder should be provided to the mobile station. The contextual reminder can be provided to the mobile station based on the comparison. The reminder can be provided when at least one of the time, the date and the geographical position of the mobile station is proximate to at least one of the time, date, and location of the entry. | 08-21-2014 |
Patent application number | Description | Published |
20090008514 | UNIVERSAL SUSPENDED ANCHOR SYSTEM - A universal suspended anchor system is configured for attaching to a frame having a first vertical wall and a second vertical wall having first and second bearing surfaces, respectively adjacent to and aligned with one another and defining a gap formed between the adjacent bearing surfaces. The universal suspended anchor system includes a bracket and a threaded block affixed to the bracket. The anchor is inserted into the gap and rests on the bearing surfaces. The anchor enables suspension of building service lines including water, HVAC and electrical services. | 01-08-2009 |
20090165600 | PNEUMATIC FASTENER DRIVING TOOL - A pneumatic fastener driving tool is configured to drive a threaded fastener using both linear and rotational motion. The tool allows a fastener to first be driven linearly, without rotation, through a surface material and into a substrate material, preferably to a depth that causes the fastener to at least pierce the substrate material. The tool then rotates the threaded fastener and causes it to fully engage the substrate material, thereby fastening the surface material to the substrate material. The tool has sufficient linear force to drive a fastener into relatively hard substrate materials, such as steel studs, and has a stationary air motor assembly to reduce recoil generated during the driving process. The tool further comprises a gear reducer assembly that uses a compound planetary gear in order to reduce the overall length of the tool. | 07-02-2009 |
20100219317 | Anchor assembly with large range of motion suspension members, and restraint systems for suspended components - An anchor assembly structured for use in connection with ceiling or roofing structures for hanging industrial or commercial components, such as, for example, electrical conduits, heating units, water pipes for automatic water sprinkler systems, and the like. The anchor assembly is easy and quick to install, and also provides enhanced swivel capabilities or angular ranges of movement so as to accommodate various system and spatial requirements in connection with the suspension of the components. Suspension and lateral restraint systems are also disclosed. | 09-02-2010 |