Kohlmann, DE
Alexander Kohlmann, Neumarkt I.d. Opf DE
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20150024948 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 01-22-2015 |
Alexander Kohlmann, Neumarkt DE
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20090118132 | Classification of Acute Myeloid Leukemia - The present invention relates to rapid and reliable approaches to leukemia prognostication. In addition to methods, the invention also provides related kits and systems. | 05-07-2009 |
Alexander Kohlmann, Neumarkt I.d.opf DE
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20120252690 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 10-04-2012 |
Anna Kohlmann, Frankfurt Am Main DE
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20120015933 | Spirocyclic nitriles as protease inhibitors - The invention relates to substituted carbo- and heterocyclic spiro compounds of the formula Ia which inhibit thiol proteases, to processes for their preparation and to the use thereof as medicaments. | 01-19-2012 |
Benjamin Kohlmann, Feuchtwangen DE
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20130022385 | ADJUSTABLE WIPER - The invention relates to a cosmetics unit, in particular a mascara unit, that includes a storage container for storing the cosmetic to be applied, an applicator which in its stowed position preferably dips into the cosmetic, and a wiper device which wipes off a portion of the cosmetic picked up by the applicator during dipping. The wiper device consists of several wipers that produce a different wiping action and through which the applicator can be passed alternatively. | 01-24-2013 |
20150026906 | WIRE CORE BRUSH WITH A PLURALITY OF LOOPS COMPOSED OF A SINGLE FILAMENT - A wire core brush with a core composed of at least two wires or wire legs twisted together, between which a large number of application elements composed of filament are held in a clamped fashion, each being embodied in the form of a loop whose ends are both affixed to the wire core, in which a large number of application elements that are each composed of a loop are composed of a single filament, which is clamped in one piece between the wires that are twisted together. | 01-29-2015 |
20150033489 | TWISTED BRUSH WITH PARALLEL BRISTLES AT THE DISTAL END - A wire core brush composed of a core comprising at least two wires twisted together between which are held bristle-forming elements, which form bristles that protrude from the core, characterized in that the wire core brush has been produced in such a way that after the twisting, it has first bristles protruding from the core essentially in the radial direction with a first length and also has second bristles protruding from the core essentially in the radial direction with a second length that is greater than the first length so that the second bristles protrude beyond the first bristles essentially in the radial direction; after this, the brush has been pulled through a hot tube whose inner diameter and temperature are selected and matched to the residence time of the brush in the tube so that a section of the second bristles is permanently oriented essentially parallel to the longitudinal axis of the wire core. | 02-05-2015 |
Jochen Kohlmann, Villingen-Schwenningen DE
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20100293181 | VALUEpilot - METHOD AND APPARATUS FOR ESTIMATING A VALUE OF A VEHICLE - The present invention relates to a method for generating an estimated value of a car, comprising the steps of receiving a user query specifying at least the type of a car; providing a database which comprises datasets having a car specification dataset specifying at least the type of the car and a car value field assigned to the respective car specification dataset representing the reference value of the car specified in the car specification dataset; searching in the database to find one or more datasets matching the user query; and calculating the estimated value of the car using the car value fields of the found datasets. | 11-18-2010 |
Lars Kohlmann, Berlin DE
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20100155257 | Aqueous, alkaline, cyanide-free bath for the galvanic deposition of zinc alloy coatings - An aqueous, alkaline, cyanide-free electrolyte bath for deposition of zinc alloy layers on substrate surfaces is described, which contains cationic pyridinium compounds as brighteners and polyamines as complexing agents. The electrolyte bath is suitable for electroplating bright and even zinc alloy coatings. | 06-24-2010 |
20100236936 | Aqueous,alkaline,cyanide-free bath for the galvanic deposition of zinc and zinc alloy coatings - The invention relates to an aqueous, alkaline cyanide-free electrolyte bath for de-positing zinc and zinc alloy coatings on substrate surfaces comprising (a) a source for zinc ions and optionally a source for further metal ions, (b) hydroxide ions, (c) a polymer of general formula I which is soluble in the bath and (d) at least one pyridinium compound of general formula II or III. The electrolyte bath is suitable for the galvanic deposition of bright and even zinc and zinc alloy coatings. | 09-23-2010 |
20100300890 | PYROPHOSPHATE-BASED BATH FOR PLATING OF TIN ALLOY LAYERS - An aqueous cyanide-free electrolyte bath for plating of tin alloy layers on substrate surfaces comprising (i) a tin ion source and a source for another alloy element, characterised in that it further contains (ii) N-methyl pyrrolidone is described. | 12-02-2010 |
20100326838 | PYROPHOSPHATE-CONTAINING BATH FOR CYANIDE-FREE DEPOSITION OF COPPER-TIN ALLOYS - A pyrophosphate-containing bath for the cyanide-free deposition of copper alloys on substrate surfaces, comprising a reaction product of a secondary monoamine with a diglycidyl ether, is described. The electrolyte bath is suitable for the galvanic deposition of glossy white, even and uniform copper-tin alloy coatings. | 12-30-2010 |
20120160698 | POLYMERS HAVING TERMINAL AMINO GROUPS AND USE THEREOF AS ADDITIVES FOR ZINC AND ZINC ALLOY ELECTRODEPOSITION BATHS - Additives for electrolyte baths for the electrodeposition of zinc or zinc alloy layer are described. The additives are polymers with terminal amino groups. These polymers are obtainable by reaction of at least one diamino compound (having two tertiary amino groups) with at least one di(pseudo)halogen compound, wherein the diamino compound is used in stoichiometric excess. The additives effect, in particular, a very little formation of bubbles and only few burnings as well as a uniform distribution of layer thickness in the electrodeposition of zinc or zinc alloy layers. | 06-28-2012 |
20140124376 | PYROPHOSPHATE-CONTAINING BATH FOR CYANIDE-FREE DEPOSITION OF COPPER-TIN ALLOYS - A pyrophosphate-containing bath for the cyanide-free deposition of copper alloys on substrate surfaces, comprising a reaction product of a secondary monoamine with a diglycidyl ether, is described. The electrolyte bath is suitable for the galvanic deposition of glossy white, even and uniform copper-tin alloy coatings. | 05-08-2014 |
20150299883 | COPPER PLATING BATH COMPOSITION - The present invention relates to aqueous acidic plating baths for copper and copper alloy deposition in the manufacture of printed circuit boards, IC substrates, semiconducting and glass devices for electronic applications. The plating bath according to the present invention comprises copper ions, at least one acid and an ureylene polymer comprising amino residues on both termini and which is free of organically bound halogen. The plating bath is particularly useful for filling recessed structures with copper and build-up of pillar bump structures. | 10-22-2015 |
20160053395 | GALVANIC NICKEL OR NICKEL ALLOY ELECTROPLATING BATH FOR DEPOSITING A SEMI-BRIGHT NICKEL OR NICKEL ALLOY - The present invention is related to a galvanic nickel or nickel alloy electroplating bath for depositing a semi-bright nickel or nickel alloy coating characterized in that the electroplating bath comprises at least one compound having the general formula (I) | 02-25-2016 |
Markus Kohlmann, Liederbach DE
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20100081671 | Cycloalkylamine substituted isoquinoline derivatives - The invention relates to 6-substituted isoquinoline derivatives of the formula (I) | 04-01-2010 |
20110021537 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDESAS P2Y12 ANTAGONISTS - The present invention relates to compounds of the formula I, | 01-27-2011 |
Markus Kohlmann, Frankfurt Am Main DE
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20130085128 | 6-(4-Hydroxy-phenyl)-3-alkyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors - The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, | 04-04-2013 |
Peter Kohlmann, Bremen DE
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20100135554 | Method and Apparatus for Determining Medical Image Position - A method and a corresponding apparatus for determining a position in an image, in particular a medical image enables a reliable determination of positions of interest in images of a variety of structures by displaying a volume rendering of image data acquired from an object, in particular a patient, pointing at a structure of interest displayed in the volume rendering of the image data, generating a viewing ray profile comprising information characterizing a ray running through said structure of interest, selecting a contextual profile from various contextual profiles, each of said contextual profiles comprising a representative ray profile representing a viewing ray profile of a structure, in particular an anatomical structure, and comprising profile information, and determining a position within said structure of interest based on said profile information of said selected contextual profile in the case that the representative ray profile of said selected contextual profile is matching with at least a part of said viewing ray profile. | 06-03-2010 |
Peter Kohlmann, Limbach/baden DE
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20120009081 | ALUMINUM ALLOY - The invention relates to an aluminum alloy having good electrical conductivity and good thermal conductivity for producing die-cast components, containing: 8.0 to 9.0 wt % silicon, 0.5 to 0.7 wt % iron, max. 0.010 wt % copper, max. 0.010 wt % magnesium, max. 0.010 wt % manganese, max. 0.001 wt % chromium, max. 0.020 wt % titanium, max. 0.020 wt % vanadium, max. 0.05 wt % zinc, 0.010 to 0.030 wt % strontium, and aluminum as the rest, with further elements and manufacturing-caused impurities individually max. 0.05 wt %, in total max. 0.2 wt %. The alloy is suited in particular for producing components having good electrical conductivity and good thermal conductivity in the die casting process. | 01-12-2012 |
Stefanie Kohlmann, Unterhaching DE
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20130052203 | IN VIVO SCREENING MODELS FOR TREATMENT OF QC-RELATED DISORDERS - A double transgenic non-human animal, in particular a transgenic mouse encoding Qpct proteins, which have been implicated in Qpct-related diseases, and Amyloid Precursor Protein (APP). Also provided are cells and cell lines comprising transgenes encoding for Qpct and APP. Also provided are methods and compositions for evaluating agents that affect Qpct, for use in compositions for the treatment of Qpct-related diseases. | 02-28-2013 |
Uwe Kohlmann, Filderstadt-Harthausen DE
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20160101754 | SUPPORT ASSEMBLY OF A BUMPER ON A FRONT MODULE OF A MOTOR VEHICLE - A support assembly of a bumper on a front end region of a motor vehicle which has a front end beam with respective headlights supported thereon and which each have a headlight housing, and which has a bumper cladding of the bumper which is supported by at least one bumper beam, is disclosed. The bumper beam is supported via at least one respective support element on the respectively allocated headlight housing of the respectively allocated headlight. Also disclosed is a headlight having a headlight housing which includes at least one receiver on which an allocated support element of a bumper is able to be supported. A method for the production of such a support assembly is also disclosed. | 04-14-2016 |
Wilfried Kohlmann, Aldenhoven DE
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20100207523 | HALOGEN INCANDESCENT LAMP AND METHOD FOR MANUFACTURING SUCH A LAMP - A halogen incandescent lamp for operating on line voltage, comprising a sealed bulb made from a transparent material and having a pinch at one end, a filling made from an inert gas and a halogen additive, and a luminous element comprised of a filament, wherein both ends of said filament are each connected with a contact element extending through the pinch, wherein a support structure is mounted in the lamp and extends in the bulb holding the filament in a predetermined shape, wherein the support structure comprises at least one metal support wire having an end part for engaging the filament, and wherein the support structure comprises an insulating glass mount, wherein said support wire is embedded in said glass mount such that no part of said metal support wire, or parts electrically connected therewith other than the contact elements, extend outside the lamp. | 08-19-2010 |