Patent application number | Description | Published |
20100090797 | VEHICLE SECURITY SYSTEM - A vehicle is disclosed which includes a controller having at least one of a vehicle security module and a playback module. The vehicle security module may operate in a secure once mode of operation or in a secure all mode of operation. The playback module records ride information associated with the vehicle. The ride information may be provided to an external device. | 04-15-2010 |
20110297462 | ELECTRONIC THROTTLE CONTROL - An electronic throttle control (ETC) system is disclosed for use on a recreational or a utility vehicle. The ETC system includes a drive mode selection device for selecting between a plurality of drive modes. The ETC system provides an adjustable engine idle speed and an engine power limiting feature. | 12-08-2011 |
20110297463 | ELECTRONIC THROTTLE CONTROL - An electronic throttle control (ETC) system is disclosed for use on a recreational or a utility vehicle. The ETC system includes a drive mode selection device for selecting between a plurality of drive modes. The ETC system provides an adjustable engine idle speed and an engine power limiting feature. | 12-08-2011 |
20110301825 | ELECTRONIC THROTTLE CONTROL - An electronic throttle control (ETC) system is disclosed for use on a recreational or a utility vehicle. The ETC system includes a drive mode selection device for selecting between a plurality of drive modes. The ETC system provides an adjustable engine idle speed and an engine power limiting feature. | 12-08-2011 |
20130240272 | NON-PNEUMATIC TIRE - A non-pneumatic tire is disclosed where a resilient wheel is mounted on a rim and the wheel has an inner ring, an outer ring and a plurality of flexible webs interconnected between the inner and outer rings. The flexible webs define openings in through the resilient wheel. The stiffness of the inner wheel at a position adjacent to the inner face is different than the stiffness of the inner wheel at a position adjacent to the outer face. This stiffness difference can be accomplished by providing inflated membranes in at least some of the openings or by molding the wheel with an asymmetric parting line. In addition, the wheels could be dynamically controlled by providing magnetically actuable membranes in some of the openings. | 09-19-2013 |
20140244110 | RECREATIONAL VEHICLE INTERACTIVE VEHICLE INFORMATION, TELEMETRY, MAPPING, AND TRIP PLANNING - An interactive system for use in connection with recreational vehicle usage includes a server system, including an off-road trail database containing trail data, trail condition information, and points-of-interest information, as well as a trip mapping system accessible by any of a plurality of riders, allowing a rider to create a route based on the data in the off-road trip database. The server system further includes a trail maintenance interface accessible by users affiliated with an authorized group to edit the trail data, trail condition information, and points-of-interest information associated with the authorized group. The server system includes a location data management system configured to receive location data, allowing a rider to publish location information to one or more other riders, and a user feedback interface configured to receive trip data from riders for publication, including information describing an actual route and user data associated with that route. | 08-28-2014 |
20150197215 | VEHICLE SECURITY SYSTEM - A vehicle is disclosed which includes a controller having at least one of a vehicle security module and a playback module. The vehicle security module may operate in a secure once mode of operation or in a secure all mode of operation. The playback module records ride information associated with the vehicle. The ride information may be provided to an external device. | 07-16-2015 |
20160003621 | RECREATIONAL VEHICLE INTERACTIVE TELEMETRY, MAPPING, AND TRIP PLANNING SYSTEM - An interactive system for use in connection with recreational vehicle usage includes a server system, including an off-road trail database containing trail data, trail condition information, and points-of-interest information, as well as a trip mapping system accessible by any of a plurality of riders, allowing a rider to create a route based on the data in the off-road trip database. The server system further includes a trail maintenance interface accessible by users affiliated with an authorized group to edit the trail data, trail condition information, and points-of-interest information associated with the authorized group. The server system includes a location data management system configured to receive location data, allowing a rider to publish location information to one or more other riders, and a user feedback interface configured to receive trip data from riders for publication, including information describing an actual route and user data associated with that route. | 01-07-2016 |
Patent application number | Description | Published |
20090047868 | Suspension-styled brassiere primarily for minimization of intra-breast wrinkling - A brassiere for minimizing the effects of wrinkling in the decolletage of a wearer's body, the brassier having two cups for the wearer's breasts and a central space therebetween, having a pouch wovenly positioned in the central space, the pouch having a suspension-styled stitching assembly for articulating the cups and hence the women's breasts in a structural and weight supported manner such that when the wearer is in a supine position the breasts are disinclined to sag; an aperture for receiving one or more articles; and a rear aperture such that the rear aperture leaves skin in the decolletage open for contact with said one or more articles. The articles are selected from the group consisting of a wickable stuffing material, foam material, memory-styled foam material, medicament, transdermal patch, and a squeezable tubular assembly. Additional suspension-styled stitching is shown in a plurality of different regions sufficient to assist the wearer's body in the opening of anterior muscles of the chest, minimizing spinal compression, relieving overstretching and/or spasmodic conditions of the mid and upper back muscles, and reductioin in overtightening of the pectoralis muscles. | 02-19-2009 |
20120256929 | EXPANDABLE MULTI-CORE TELECOMMUNICATION AND VIDEO PROCESSING APPARATUS - An expandable multi-core telecommunication and video processing apparatus includes a primary wireless telecommunications device having a microprocessor that can be programed for running a wide range of software application and includes a primary, or main, viewer touch screen interface and a plurality of ports for receiving one or more video core processors. Each video core processor is removably connectable to a port located along a surface of the primary telecommunications device for permitting a plurality of individual videos which can be interfaced by a user. The individual videos displaced by each connected video core processor can act in concert with, or independently of, the main, or primary, touch screen interface which is located on a front surface of the primary telecommunications device. The primary telecommunications device further includes a detachable storage bay for retaining video core processors when not connected with the primary telecommunications device. The primary telecommunications device and the video core processors are, preferably, each connectable to a docking station, which can download data from either a video core processor or the primary telecommunications device. The docking station can be connected to a personal computer. | 10-11-2012 |
20120326972 | MULTI-TASK INTERACTIVE WIRELESS TELECOMMUNICATIONS DEVICE - A portable wireless telecommunications device has electronic computer visual display includes at least one central display screen and at least two additional screens respectively disposed foldably to the right and left of said central screen, for displaying simultaneous, multiple images to a user in a super video graphics array (SVGA). The foldable display has at least two mutually connected foldable sub-display units, and it includes a user attachable and detachable connector, for user-assembling of the sub-display units into mutual connection with each other. Each of the two sub-display units have user-deployable supports (e.g. a rigid angular support member) for maintaining the sub-display units in an upwardly projecting disposition during use. | 12-27-2012 |
Patent application number | Description | Published |
20150030601 | E1 ENZYME MUTANTS AND USES THEREOF - The invention provides isolated nucleic acids molecules, designated UBA3, UAE, or UBA6, or other E1 enzyme variant nucleic acid molecules, which encode novel E1 enzyme variant proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing UBA3, UAE, or UBA6, or other E1 enzyme variant nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a UBA3, UAE, or UBA6, or other E1 enzyme variant gene has been introduced or disrupted. The invention still further provides isolated UBA3, UAE, or UBA6, or other E1 enzyme variant proteins, fusion proteins, antigenic peptides and anti-UBA3, UAE, or UBA6, or other E1 enzyme variant antibodies. The invention provides methods to identify agents that inhibit UBA3, UAE, or UBA6, or other E1 enzyme variant expression or activity. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. | 01-29-2015 |
20150152502 | BIOMARKERS OF RESPONSE TO PROTEASOME INHIBITORS - Disclosed are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are further provided to assess markers of marker genes to predict outcome of treatment using proteasome inhibitors to patients having a solid tumor, such as a lung tumor or a colon tumor. | 06-04-2015 |
20150184246 | BIOMARKERS OF RESPONSE TO PROTEASOME INHIBITORS - Disclosed herein are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are provided to assess markers of marker genes to predict outcome with proteasome inhibition treatment | 07-02-2015 |
Patent application number | Description | Published |
20110124631 | TREATMENT OF COGNITIVE DISORDERS WITH CERTAIN ALPHA-7 NICOTINIC ACID RECEPTORS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS - A method for improving cognition comprising administering to a patient (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof and an acetylcholinesterase inhibitor is described together with related compositions. | 05-26-2011 |
20110288119 | Low dose - prov (alpha 7-EVP) - (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses improve cognition. | 11-24-2011 |
20130137717 | Treatment of Cognitive Disorders with (R)-7-Chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-Carboxamide and Pharmaceutically Acceptable Salts Thereof - (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses to improve cognition. | 05-30-2013 |
20130225560 | Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Acetylcholinesterase Inhibitors - A method for improving cognition comprising administering to a patient certain alpha-7 receptor agonists and an acetylcholinesterase inhibitor is described together with related compositions. | 08-29-2013 |
20130231365 | Treatment of Inflammation with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Acetylcholinesterase Inhibitors - A method for treating inflammation comprising administering to a patient (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof or (R)-7-(2-methoxyphenyl)-N-(quinuclidin-3-yl)benzofuran-2-carboxamide or certain other alpha 7 receptor agonists combination with an acetylcholinesterase inhibitor. | 09-05-2013 |
20140148479 | Treatment of Cognitive Disorders with (R)-7-Chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-Carboxamide and Pharmaceutically Acceptable Salts Thereof - (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses to improve cognition. | 05-29-2014 |
20140155429 | Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Nicotine - A method for improving cognition comprising co-administering to a subject an alpha 7 agonist, or a pharmaceutically acceptable salt thereof and a tobacco-free nicotine dosage is described together with related compositions. | 06-05-2014 |
20140155430 | TREATMENT OF COGNITIVE DISORDERS WITH (R)-7-CHLORO-N-(QUINUCLIDIN-3-YL)BENZO[B]THIOPHENE-2-CARBOXAMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF - (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses to improve cognition. | 06-05-2014 |
20140163067 | Methods of Treatment of Limited Cognitive Impairment - A method for improving or treating a Limited Cognitive Impairment (LCI) comprising administering to a subject a compound of the invention, or a pharmaceutically acceptable salt thereof is described together with related compositions. | 06-12-2014 |
20140179678 | METHODS OF TARGETED TREATMENT OF FRONTOTEMPORAL LOBAR DEGENERATION - The present invention provides targeted treatment to subjects suffering from Frontotemporal lobar degeneration through use of FTLD targeted agents, as described in the present invention. In particular, the FTLD targeted agents provided herein demonstrate high brain penetration, which decreases risk issues associated with peripheral administration. Furthermore, the FTLD targeted agents of the present invention, when administered to a subject selected for treatment based on the results of a FTLD diagnostic assay, offer targeted treatment of FTLD. | 06-26-2014 |
20140330014 | IMIDAZOTRIAZINONE COMPOUNDS - The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans. | 11-06-2014 |
20150126546 | Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptors in Combination with Acetylcholinesterase Inhibitors - A method for improving cognition comprising administering to a patient (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof and an acetylcholinesterase inhibitor is described together with related compositions. | 05-07-2015 |
20150126547 | Methods of Maintaining, Treating or Improving Cognitive Function - A method of administering an effective amount of (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, or a pharmaceutically acceptable salt thereof, to a patient in need thereof. | 05-07-2015 |
20150265583 | Treatment of Cognitive Disorders with (R)-7-Chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-Carboxamide and Pharmaceutically Acceptable Salts Thereof - (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses to improve cognition. | 09-24-2015 |
Patent application number | Description | Published |
20120145012 | SYSTEM AND METHOD FOR CRUSHING AND COMPACTION - An exemplary embodiment of a screw crusher may utilize a cantilevered screw with an inverse tapered shaft with flighting for conveying the product up the length of the shaft for compression. The screw may include an end flight configured to provide thrust to the product for further conveyance beyond the end of the screw or additional compaction when utilized with a receiving container. An exemplary embodiment of the screw crusher may utilize a single moving element in relation to a cylindrical tube for compression of the product. Also, an exemplary screw compactor may utilize a fixed replaceable restrictor tube section and an efficient screw design making it more cost effective and efficient to operate than other known compactors. Furthermore, an example of the screw crusher may be fitted with perforated or the preferred “V” Slotted tube to perform liquid removal in addition to the compaction of the material. | 06-14-2012 |
20120145814 | SYSTEM AND METHOD FOR CRUSHING - A system for crushing material that may include a compaction chamber and a screw assembly that generally extends between the proximal and distal ends of the compaction chamber. In one embodiment, a portion of the screw assembly increases in diameter along a length of the shaft of the screw assembly such that the system is configured to crush material between the compaction chamber and the portion that increases in diameter. The portion that increases in diameter may be integral with the shaft of the screw assembly. An embodiment of the system may also include at least one wear member that is removably associated with the distal portion of the compaction chamber such that the wear member may assist with crushing. Further embodiments may include improved input, discharge, and/or jam clearance means for a screw crusher or other types of screw or auger systems. | 06-14-2012 |
20120145815 | SYSTEM AND METHOD FOR CRUSHING - Exemplary embodiments are for a system for crushing a material that may include a compaction chamber and a screw assembly that generally extends between the proximal and distal ends of the compaction chamber. A portion of the screw assembly increases in diameter along a length of the shaft of the screw assembly such that the system is configured to crush material between the compaction chamber and the portion of the screw assembly that increases in diameter. The portion of the screw assembly that increases in diameter may be integral with the shaft of the screw assembly. An exemplary embodiment of the system may also include at least one wear member that is removably associated with the distal portion of the compaction chamber such that the wear member may assist with the crushing of material. | 06-14-2012 |
20130299315 | CANTILEVERED SCREW ASSEMBLY - An exemplary embodiment is directed to a cantilevered screw assembly comprising a solid oil bearing to facilitate rotation of the screw. Another exemplary embodiment of a cantilevered screw assembly includes an improved anchor system comprising multiple load-bearing walls. In particular, an exemplary embodiment may comprise a screw that is cantilevered to at least two walls. At least one reinforcement member may connect the walls for additional support. | 11-14-2013 |
20140261829 | OUTLET TUBE FOR A MATERIAL TRANSFER SYSTEM - An outlet tube for a material transfer system. The outlet tube comprises a body and at least one restrictor. The body is adapted to be connected to a feed system. The body has an inner wall that defines an opening adapted to receive material from the feed system such that the body is adapted to allow a flow of the material through the opening and out of the tube. At least one restrictor extends inwardly from the inner wall of the body into the opening. The restrictor(s) is adapted to extend into the flow of the material to impede the flow. In addition, the restrictor(s) is configured to enable the material to flow around it to exit out of the tube. | 09-18-2014 |
20140264130 | ISOLATION GATE - A gate comprising a frame and a blade. The frame defines an opening that is adapted to be opened and closed, and the blade is associated with the frame such that the blade is adapted to open and close the opening. For such purpose, the blade is adapted to move along a path defined by the frame between an open position and a closed position. | 09-18-2014 |
20140271047 | SYSTEM FOR PROCESSING MATERIAL FOR A GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. A tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. The tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 09-18-2014 |
20140271096 | METHOD FOR PROCESSING MATERIAL FOR A GASIFIER - A method for providing material to a gasifier. The method comprises providing a feedstock. A flow of the feedstock is formed. The flow is then delivered to a gasifier such that it provides a substantially airtight seal to the gasifier. | 09-18-2014 |
20140311869 | PRESSURE RELIEF TUBE FOR AUGER - A pressure relief tube or enclosure such as for an auger screw. In one embodiment, a pressure relief tube may comprise at least one hatch that is adapted to expand in response to force applied from within the tube. An example of the pressure relief tube may automatically adapt or adjust to potential problem material in the tube to allow for conveyance or clearance of the problem material. Another example of the pressure relief tube may be manually adapted or adjusted to facilitate conveyance or clearance of the problem material. Related systems and methods comprising a pressure relief tube are also provided. | 10-23-2014 |
20140339346 | FEED DELIVERY SYSTEM AND METHOD FOR GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. In an exemplary embodiment, a tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. In such an embodiment, the tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 11-20-2014 |
20150175912 | FEED DELIVERY SYSTEM AND METHOD FOR GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. In an exemplary embodiment, a tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. In such an embodiment, the tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 06-25-2015 |
20150202632 | DUAL AUGER SHREDDER HAVING LOW PROFILE - An auger system adapted to shred large materials. An exemplary embodiment is comprised of dual opposing augers that are adapted to grab, compress, and shred the material, reducing the material size such that it may be discharged through a side outlet opening and/or an extrusion tube into, for example, a standard roll-off compaction container. An exemplary embodiment allows large material to be processed in a low speed device with reduced equipment dimensions, providing operator safety with low profile loading, lower noise level, reduced chances of material being expelled from the processing chamber, and ability to use conventional material transport (e.g., semi-trucks). | 07-23-2015 |
20150336746 | CANTILEVERED SCREW ASSEMBLY - An exemplary embodiment is directed to a cantilevered screw assembly comprising a solid oil bearing to facilitate rotation of the screw. Another exemplary embodiment of a cantilevered screw assembly includes an improved anchor system comprising multiple load-bearing walls. In particular, an exemplary embodiment may comprise a screw that is cantilevered to at least two walls. At least one reinforcement member may connect the walls for additional support. | 11-26-2015 |
Patent application number | Description | Published |
20110046121 | INHIBITORS OF FOCAL ADHESION KINASE - The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions. | 02-24-2011 |
20120309757 | N-BIPHENYLMETHYLINDOLE MODULATORS OF PPARG - The invention provides molecular entities that bind with high affinity to PPARG (PPARγ), inhibit kinase-mediated, e.g., cdk5-mediated, phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes, insulin resistance, impaired glucose tolerance, pre-diabetes, hyperglycemia, hyperinsulinemia, obesity, or inflammation. In methods of treatment of these conditions using a compound of the invention, the compound can avoid producing side effects of significant weight gain, edema, impairment of bone growth or formation, or cardiac hypertrophy, or any combination thereof, in the patient receiving the compound. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided. | 12-06-2012 |
20120309769 | N-BENZYLINDOLE MODULATORS OF PPARG - The invention provides molecular entities that bind with high affinity to PPARG (PPARγ), and inhibit kinase-mediated (e.g., cdk5-mediated) phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes, insulin resistance, impaired glucose tolerance, pre-diabetes, hyperglycemia, hyperinsulinemia, obesity, or inflammation. Side effects such as significant weight gain, edema, impairment of bone growth or formation, or cardiac hypertrophy, or any combination thereof, can be avoided in the mammal receiving the compound. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided. | 12-06-2012 |
20130281443 | INHIBITORS OF FOCAL ADHESION KINASE - The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions. | 10-24-2013 |
20140187554 | MODULATORS OF THE NUCLEAR HORMONE RECEPTOR ROR - The invention provides small molecule modulators of retinoic acid receptor-related orphan receptors such as RORα, RORβ, or RORγ. Compounds of the invention can be effective modulators at concentrations ineffective to act on LXR receptors, or on other nuclear receptors, or other biological targets. Methods of modulation the RORs and methods of treating metabolic disorders, immune disorders, cancer, and CNS disorders wherein modulation of an ROR is medically indicated are also provided. | 07-03-2014 |
Patent application number | Description | Published |
20120145012 | SYSTEM AND METHOD FOR CRUSHING AND COMPACTION - An exemplary embodiment of a screw crusher may utilize a cantilevered screw with an inverse tapered shaft with flighting for conveying the product up the length of the shaft for compression. The screw may include an end flight configured to provide thrust to the product for further conveyance beyond the end of the screw or additional compaction when utilized with a receiving container. An exemplary embodiment of the screw crusher may utilize a single moving element in relation to a cylindrical tube for compression of the product. Also, an exemplary screw compactor may utilize a fixed replaceable restrictor tube section and an efficient screw design making it more cost effective and efficient to operate than other known compactors. Furthermore, an example of the screw crusher may be fitted with perforated or the preferred “V” Slotted tube to perform liquid removal in addition to the compaction of the material. | 06-14-2012 |
20120145814 | SYSTEM AND METHOD FOR CRUSHING - A system for crushing material that may include a compaction chamber and a screw assembly that generally extends between the proximal and distal ends of the compaction chamber. In one embodiment, a portion of the screw assembly increases in diameter along a length of the shaft of the screw assembly such that the system is configured to crush material between the compaction chamber and the portion that increases in diameter. The portion that increases in diameter may be integral with the shaft of the screw assembly. An embodiment of the system may also include at least one wear member that is removably associated with the distal portion of the compaction chamber such that the wear member may assist with crushing. Further embodiments may include improved input, discharge, and/or jam clearance means for a screw crusher or other types of screw or auger systems. | 06-14-2012 |
20120145815 | SYSTEM AND METHOD FOR CRUSHING - Exemplary embodiments are for a system for crushing a material that may include a compaction chamber and a screw assembly that generally extends between the proximal and distal ends of the compaction chamber. A portion of the screw assembly increases in diameter along a length of the shaft of the screw assembly such that the system is configured to crush material between the compaction chamber and the portion of the screw assembly that increases in diameter. The portion of the screw assembly that increases in diameter may be integral with the shaft of the screw assembly. An exemplary embodiment of the system may also include at least one wear member that is removably associated with the distal portion of the compaction chamber such that the wear member may assist with the crushing of material. | 06-14-2012 |
20130192478 | MATERIAL WASTE SORTING SYSTEM AND METHOD - Exemplary embodiments include improved systems and methods for sorting and metering materials to be recycled at a material recovery facility. Systems and methods for the accurate and automated sorting and metering of recoverable materials may include a bunker with an integral conveyor adapted to meter presorted materials such that predetermined amounts of the materials may be delivered to a baler for baling and sale. Exemplary systems may include an auger screw type conveyor sized and shaped to deliver the materials to, for example, a baling system. The systems may also include a crusher for reducing the volume of the materials prior to metering from the bunker; by reducing the volume of the materials in the bunker, a baler may operate more efficiently, increasing output from the facility. | 08-01-2013 |
20130299315 | CANTILEVERED SCREW ASSEMBLY - An exemplary embodiment is directed to a cantilevered screw assembly comprising a solid oil bearing to facilitate rotation of the screw. Another exemplary embodiment of a cantilevered screw assembly includes an improved anchor system comprising multiple load-bearing walls. In particular, an exemplary embodiment may comprise a screw that is cantilevered to at least two walls. At least one reinforcement member may connect the walls for additional support. | 11-14-2013 |
20140261829 | OUTLET TUBE FOR A MATERIAL TRANSFER SYSTEM - An outlet tube for a material transfer system. The outlet tube comprises a body and at least one restrictor. The body is adapted to be connected to a feed system. The body has an inner wall that defines an opening adapted to receive material from the feed system such that the body is adapted to allow a flow of the material through the opening and out of the tube. At least one restrictor extends inwardly from the inner wall of the body into the opening. The restrictor(s) is adapted to extend into the flow of the material to impede the flow. In addition, the restrictor(s) is configured to enable the material to flow around it to exit out of the tube. | 09-18-2014 |
20140264130 | ISOLATION GATE - A gate comprising a frame and a blade. The frame defines an opening that is adapted to be opened and closed, and the blade is associated with the frame such that the blade is adapted to open and close the opening. For such purpose, the blade is adapted to move along a path defined by the frame between an open position and a closed position. | 09-18-2014 |
20140271047 | SYSTEM FOR PROCESSING MATERIAL FOR A GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. A tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. The tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 09-18-2014 |
20140271096 | METHOD FOR PROCESSING MATERIAL FOR A GASIFIER - A method for providing material to a gasifier. The method comprises providing a feedstock. A flow of the feedstock is formed. The flow is then delivered to a gasifier such that it provides a substantially airtight seal to the gasifier. | 09-18-2014 |
20140311869 | PRESSURE RELIEF TUBE FOR AUGER - A pressure relief tube or enclosure such as for an auger screw. In one embodiment, a pressure relief tube may comprise at least one hatch that is adapted to expand in response to force applied from within the tube. An example of the pressure relief tube may automatically adapt or adjust to potential problem material in the tube to allow for conveyance or clearance of the problem material. Another example of the pressure relief tube may be manually adapted or adjusted to facilitate conveyance or clearance of the problem material. Related systems and methods comprising a pressure relief tube are also provided. | 10-23-2014 |
20140339346 | FEED DELIVERY SYSTEM AND METHOD FOR GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. In an exemplary embodiment, a tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. In such an embodiment, the tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 11-20-2014 |
20150175912 | FEED DELIVERY SYSTEM AND METHOD FOR GASIFIER - A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. In an exemplary embodiment, a tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. In such an embodiment, the tube is also connected to a gasifier, which is adapted to receive the material from the tube. | 06-25-2015 |
20150202632 | DUAL AUGER SHREDDER HAVING LOW PROFILE - An auger system adapted to shred large materials. An exemplary embodiment is comprised of dual opposing augers that are adapted to grab, compress, and shred the material, reducing the material size such that it may be discharged through a side outlet opening and/or an extrusion tube into, for example, a standard roll-off compaction container. An exemplary embodiment allows large material to be processed in a low speed device with reduced equipment dimensions, providing operator safety with low profile loading, lower noise level, reduced chances of material being expelled from the processing chamber, and ability to use conventional material transport (e.g., semi-trucks). | 07-23-2015 |
20150336746 | CANTILEVERED SCREW ASSEMBLY - An exemplary embodiment is directed to a cantilevered screw assembly comprising a solid oil bearing to facilitate rotation of the screw. Another exemplary embodiment of a cantilevered screw assembly includes an improved anchor system comprising multiple load-bearing walls. In particular, an exemplary embodiment may comprise a screw that is cantilevered to at least two walls. At least one reinforcement member may connect the walls for additional support. | 11-26-2015 |
Patent application number | Description | Published |
20100210939 | Method and Apparatus for Surgical Navigation - Disclosed is a surgical navigation system for tracking an instrument relative to a patient. The system can track a portion of the patient, an instrument, and/or both relative to image data, a coordinate system, an atlas, a morphed atlas, or combinations thereof. The system can include a tracking device on the instrument to provide six degree of freedom information regarding the location of the instrument. | 08-19-2010 |
20100234724 | Navigating A Surgical Instrument - An instrument tracking device for cooperating with an instrument during a surgical procedure where the instrument has an elongated body extending along a first longitudinal axis and including a working member at a distal tip includes a body having a distal end and a proximal end. An opening can be formed through the body along a second longitudinal axis. The opening can define a passthrough in the body from the distal end to the proximal end. A first tracking coil can be disposed in the body and can define a first tracking coil axis that is substantially coaxial with the second longitudinal axis of the body. A connection mechanism cooperates between the elongated housing and the body that secures the body to the elongated housing of the instrument upon passing at least a portion of the elongated housing through the passthrough of the body in an assembled position. | 09-16-2010 |
20110237935 | Method and Apparatus for Guiding an External Needle to an Implantable Device - A system can include an implantable device, an instrument, a display device and a processor. The implantable device can include a port and a localizer for generating a navigation field. The instrument can include a tracking device for sensing the navigation field. The processor can be operably coupled to the tracking and display devices and operable to determine a real-time location of the instrument relative to the port and a trajectory of the instrument relative to an insertion axis of the port. The processor system can be operable to cause the display device to graphically render the instrument as a plurality of two or three-dimensional rings positioned around an axis coincident with the determined trajectory and in spaced relation to each other along the axis. A first ring of the plurality of rings can be positioned at the determined instrument location relative to a graphical representation of the port location. | 09-29-2011 |
20110237936 | Method and Apparatus for Guiding an External Needle to an Implantable Device - A support tool or a supply assembly that delivers a functional fluid to a patient includes an antenna array for receiving or sensing a navigation field. The navigation field can be generated from a localizer. The localizer can be incorporated or included in an implanted device. | 09-29-2011 |
20110237937 | Method and Apparatus for Guiding an External Needle to an Implantable Device - A system to generate a navigation field relative to an implanted device is disclosed. The system can include a small and/or thin localizer array positioned in the implanted device. A power management scheme and circuits can be provided to conserve and resource power in the implanted device. | 09-29-2011 |
20110238034 | Method and Apparatus for Guiding an External Needle to an Implantable Device - A support tool for a supply assembly delivers a functional fluid to an implantable medical device. The supply assembly defines a supply axis. The support tool includes a support member defining an opening. The opening has a support axis, and the opening is configured to receive the supply assembly. The support member includes a three dimensionally contoured nesting surface that conforms to a corresponding three dimensionally contoured surface of the supply assembly. The corresponding surface of the supply assembly nests against the nesting surface to support the supply assembly such that the supply axis remains substantially fixed relative to and aligned with the support axis. | 09-29-2011 |
20120197108 | Method and Apparatus for Image-Based Navigation - A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, tracking a substantially small tracking device in a plurality of degrees of freedom is provided. The tracking device can be positioned on or be formed in an instrument to be tracked. | 08-02-2012 |
20120197109 | Method and Apparatus for Image-Based Navigation - A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, tracking a substantially small tracking device in a plurality of degrees of freedom is provided. The tracking device can be positioned on or be formed in an instrument to be tracked. | 08-02-2012 |
20120197110 | Method and Apparatus for Image-Based Navigation - A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, tracking a substantially small tracking device in a plurality of degrees of freedom is provided. The tracking device can be positioned on or be formed in an instrument to be tracked. | 08-02-2012 |
20120275645 | Method and Apparatus for Calibrating and Re-Aligning an Ultrasound Image Plane to a Navigation Tracker - The present disclosure relates to acquiring image data of a subject with an imaging system that has been calibrated. The imaging system can include an ultrasound imaging system that collects one of more images based on a plane of image acquisition. The plane of image acquisition can be calibrated to a tracking device associated with the ultrasound transducer. | 11-01-2012 |
20120277585 | Method and Apparatus for Calibrating and Re-aligning an Ultrasound Image Plane to a Navigation Tracker - The present disclosure relates to acquiring image data of a subject with an imaging system that has been calibrated. The imaging system can include an ultrasound imaging system that collects one of more images based on a plane of image acquisition. The plane of image acquisition can be calibrated to a tracking device associated with the ultrasound transducer. | 11-01-2012 |
20130296830 | Method And Apparatus For Guiding An External Needle To An Implantable Device - A support tool for a supply assembly delivers a functional fluid to an implantable medical device. The supply assembly defines a supply axis. The support tool includes a support member defining an opening. The opening has a support axis, and the opening is configured to receive the supply assembly. The support member includes a three dimensionally contoured nesting surface that conforms to a corresponding three dimensionally contoured surface of the supply assembly. The corresponding surface of the supply assembly nests against the nesting surface to support the supply assembly such that the supply axis remains substantially fixed relative to and aligned with the support axis. | 11-07-2013 |
20130303896 | Method And Apparatus For Guiding An External Needle To An Implantable Device - A system can include an implantable device, an instrument, a display device and a processor. The implantable device can include a port and a localizer for generating a navigation field. The instrument can include a tracking device for sensing the navigation field. The processor can be operably coupled to the tracking and display devices and operable to determine a real-time location of the instrument relative to the port and a trajectory of the instrument relative to an insertion axis of the port. The processor system can be operable to cause the display device to graphically render the instrument as a plurality of two or three-dimensional rings positioned around an axis coincident with the determined trajectory and in spaced relation to each other along the axis. A first ring of the plurality of rings can be positioned at the determined instrument location relative to a graphical representation of the port location. | 11-14-2013 |
20130317355 | Navigating A Surgical Instrument - An instrument tracking device for cooperating with an instrument during a surgical procedure where the instrument has an elongated body extending along a first longitudinal axis and including a working member at a distal tip includes a body having a distal end and a proximal end. An opening can be formed through the body along a second longitudinal axis. The opening can define a passthrough in the body from the distal end to the proximal end. A first tracking coil can be disposed in the body and can define a first tracking coil axis that is substantially coaxial with the second longitudinal axis of the body. A connection mechanism cooperates between the elongated housing and the body that secures the body to the elongated housing of the instrument upon passing at least a portion of the elongated housing through the passthrough of the body in an assembled position. | 11-28-2013 |
Patent application number | Description | Published |
20080221930 | Health data collection tool - A portable health data tool permits a health care provider to assimilate and display a plurality of health care data from a patient and to associate the data with patient identifying information all stored in a memory contained in the tool. The tool includes a code reader for reading patient information into the tool from a bar code or other coded tag. The tool is associated with a plurality of different data assimilation devices stored with the tool's housing, including but not limited to, instruments for measuring, temperature, blood pressure, two-finger or lead wire ECG data, pulse oximetry data, sound data and picture data obtained from an optional digital camera integrated within the housing. The tool further includes data receiver and/or transmitter ports, which may be wireless or cable ports, for transferring data between the health data tool and a separate computer system that stores patient records. | 09-11-2008 |
20120184120 | DUAL SERIAL BUS INTERFACE - An interface protocol for patient monitoring systems includes a Dual Serial Bus (DSB) interface. The DSB interface includes a first serial protocol that is USB, Firewire, or Ethernet protocol and a second serial protocol that is a low power serial (LPS) protocol. DSB interfaces provide for communication between DSB Hosts and DSB Devices and allow for the transfer of operating and battery charging power from DSB Host to DSB Device. In addition, the DSB host contains a switched Auxiliary Voltage Supply (AVS) which can provide up to 15 W of power to DSB devices for battery charging or other high power needs. The DSB interface eliminates the need for multiple cables for different parameter sensing devices as there is only one type of connector and, accordingly, reduces the risk of damage caused by inadvertently plugging a parameter sensing device into the wrong receptacle. | 07-19-2012 |
20140054374 | Health Data Collection Tool - A portable health data tool permits a health care provider to assimilate and display a plurality of health care data from a patient and to associate the data with patient identifying information all stored in a memory contained in the tool. The tool includes a code reader for reading patient information into the tool from a bar code or other coded tag. The tool is associated with a plurality of different data assimilation devices stored with the tool's housing, including but not limited to, instruments for measuring, temperature, blood pressure, two-finger or lead wire ECG data, pulse oximetry data, sound data and picture data obtained from an optional digital camera integrated within the housing. The tool further includes data receiver and/or transmitter ports, which may be wireless or cable ports, for transferring data between the health data tool and a separate computer system that stores patient records. | 02-27-2014 |
20150134364 | Health Data Collection Tool - A portable health data tool permits a health care provider to assimilate and display a plurality of health care data from a patient and to associate the data with patient identifying information all stored in a memory contained in the tool. The tool includes a code reader for reading patient information into the tool from a bar code or other coded tag. The tool is associated with a plurality of different data assimilation devices stored with the tool's housing, including but not limited to, instruments for measuring, temperature, blood pressure, two-finger or lead wire ECG data, pulse oximetry data, sound data and picture data obtained from an optional digital camera integrated within the housing. The tool further includes data receiver and/or transmitter ports, which may be wireless or cable ports, for transferring data between the health data tool and a separate computer system that stores patient records. | 05-14-2015 |
20150301717 | Trending Display of Patient Wellness - The present invention is a novel method of generating and representing the status of various physiological parameters that are monitored for patients during hospitalization. The system of present invention allows healthcare providers to easily view, at a glance, the status or trend of a patient or a plurality of patients as well as any changes in the parameter values. | 10-22-2015 |
Patent application number | Description | Published |
20080293726 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 11-27-2008 |
20090149549 | PREPARATION OF CHIRAL AMIDES AND AMINES - This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents. Accordingly, it produces the desired compounds without the concomitant production of a large volume of metallic waste. The enamides are useful precursors to amides and amines. The invention provides a process to convert a prochiral enamide into the corresponding chiral amide. In an exemplary process, a chiral amino center is introduced during hydrogenation through the use of a chiral hydrogenation catalyst. In selected embodiments, the invention provides methods of preparing amides and amines that include the 1,2,3,4-tetrahydro-N-alkyl-1-naphthalenamine or 1,2,3,4-tetrahydro-1-naphthalenamine substructure. | 06-11-2009 |
20120095106 | PREPARATION OF CHIRAL AMIDES AND AMINES - This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents. Accordingly, it produces the desired compounds without the concomitant production of a large volume of metallic waste. The enamides are useful precursors to amides and amines. The invention provides a process to convert a prochiral enamide into the corresponding chiral amide. In an exemplary process, a chiral amino center is introduced during hydrogenation through the use of a chiral hydrogenation catalyst. In selected embodiments, the invention provides methods of preparing amides and amines that include the 1,2,3,4-tetrahydro-N-alkyl-1-naphthalenamine or 1,2,3,4-tetrahydro-1-naphthalenamine substructure. | 04-19-2012 |
20120123164 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 05-17-2012 |
20130065904 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 03-14-2013 |
20140057990 | PREPARATION OF CHIRAL AMIDES AND AMINES - This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents. Accordingly, it produces the desired compounds without the concomitant production of a large volume of metallic waste. The enamides are useful precursors to amides and amines. The invention provides a process to convert a prochiral enamide into the corresponding chiral amide. In an exemplary process, a chiral amino center is introduced during hydrogenation through the use of a chiral hydrogenation catalyst. In selected embodiments, the invention provides methods of preparing amides and amines that include the 1,2,3,4-tetrahydro-N-alkyl-1-naphthalenamine or 1,2,3,4-tetrahydro-1-naphthalenamine substructure. | 02-27-2014 |
20140315910 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 10-23-2014 |