Klaus-Peter
Klaus Peter Bogeso, Adorp NL
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20090176808 | COMBINATION OF A SEROTONIN REUPTAKE INHIBITOR AND A 5-HT2C ANTAGONIST, INVERSE AGONIST OR PARTIAL AGONIST - The present invention relates to the use of compounds and compositions of compounds having serotonin reuptake inhibiting activity and 5-HT | 07-09-2009 |
Klaus Peter Gungl, Aidlingen DE
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20090113094 | System for performing a serial communication between a central control block and satellite components - The various embodiments described herein relate to a system for performing a serial communication between a central control block and a plurality of satellite components within a semiconductor chip. The system comprises at least one logical ring that serially connects the satellite components to the central control block. The system further comprises a centralized timer. The satellite components aid the system in obeying protocols and performing direct accesses to and/or from registers. The logical ring comprises at least one data channel that is provided for transmitting data packets and address packets. Single-envelope transactions are implemented. Errors of the satellite components associated with the single-envelope transactions are reported to the central control block as additional acknowledgement information. | 04-30-2009 |
Klaus Peter Koch, Darmstadt DE
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20110224528 | FLEXIBLE, MULTI-CHANNEL MICROELECTRODE FOR RECORDING LABORATORY ANIMAL EEG AND METHOD FOR RECORDING LABORATORY ANIMAL EEG USING THE SAME - Disclosed are a novel, elastic, biocompatible, micro-sized, polyimide-based multi-channel microelectrode for recording of electroencephalography (EEG) from a laboratory animal including mouse, and a method for recording of laboratory animal EEG using the microelectrode. The microelectrode may include 2 grounding electrodes and 32 recording electrodes. A connector for signal transmission easily connects the microelectrode to a signal acquiring apparatus. The total weight of the microelectrode, including the connector, does not exceed 150 mg. Laboratory animal EEG, including that of mouse, provides the advantage of monitoring the brain state of a freely moving animal following a genetic or pharmaceutical manipulation. The microelectrode can be implanted without surgery and may be detached from wires while EEG is not recorded from the laboratory animal. The microelectrode can successfully acquire broadband EEG signals from the skull of the laboratory animal and is effective in monitoring spatial and temporal pattern of brain activities of the laboratory animal. | 09-15-2011 |
Klaus Peter Kopper, Helmenzen DE
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20090212768 | Magnetic Tagging Techniques - This invention relates to microfluidic apparatus for reading, writing and sorting magnetic tags attached to chemical and biological molecules and other entities. We describe apparatus for separating chemical or biological molecules or moieties each individually attached to a MBM tag miniature multi-bit magnetic tag capable of adopting a plurality of remanent magnetic configurations corresponding to binary information, the apparatus comprising: at least one input for said tagged molecules or moieties; at least two outputs for said tagged molecules or moieties; a microfluidic flow channel incorporating: magnetic readers to read said binary information; magnetic writers to write said binary information; and a switch to direct said tagged molecules or moieties to a selected said output responsive to said binary information. The invention also relates to planar multibit magnetic tags suitable for use with such apparatus. | 08-27-2009 |
Klaus Peter Maab, Viersen DE
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20090021044 | SEALING OR GUIDING ASSEMBLIES AND METHOD OF MAKING IT - A sealing or guiding assembly for sealing or guiding a corner of a closure member such as a window ( | 01-22-2009 |
Klaus Peter Meyer, Ratingen DE
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20100266348 | MULTICOMPONENT COMPOSITION FOR FILLING AND/OR INJECTING CRACKS, FLAWS AND CAVITIES IN STRUCTURES OR EARTH AND ROCK FORMATIONS - A multicomponent composition for filling and/or grouting cracks, flaws, and cavities in structures or earth and stone formations, including: i) water; ii) cement; iii) an aqueous plastic dispersion; and iv) at least one monomer, which can be radically polymerized, or a polyisocyanate. A material is thus obtained as a sealant, which displays great adjustment capabilities of hardness and reaction time, in addition to its cost-effectiveness. Such a composition unifies positive properties of various materials as a sealant, such as expansion capacity and swelling capacity. | 10-21-2010 |
Klaus Peter Möbius, Zoullnitz DE
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20100179068 | Assays - A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. | 07-15-2010 |
Klaus Peter Möbius, Zoullnitz DE
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20100179068 | Assays - A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. | 07-15-2010 |
Klaus Peter Moubius, Zoullnitz DE
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20100056387 | ASSAYS - A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones are disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. | 03-04-2010 |
20140148365 | Assays - A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones are disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. | 05-29-2014 |
Klaus Peter Raunecker, Ulm DE
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20150248688 | METHOD FOR OBTAINING INFORMATION - A method for ascertaining a sought piece of information by involving a plurality of subscribers. The subscribers are set a search task by an initiator and the one or more subscribers that assist with delivering a sought piece of information have the prospect of a reward. Even subscribers that, although not delivering the sought piece of information, play a part in identifying the subscriber that delivers the sought piece of information have the prospect of a share of the reward. | 09-03-2015 |
Klaus Peter Schmidt, Bonn DE
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20090000525 | Pallet - The invention relates to a pallet ( | 01-01-2009 |
20090008397 | PALLET CONTAINER - A pallet container for the storage and transport of liquid or free-flowing goods, includes a thin-walled inner container of thermoplastic material, a tubular lattice frame closely surrounding the inner plastic container in the form of a support jacket, and a bottom pallet upon which the inner plastic container rests and with which the tubular lattice frame is securely fixed. The inner plastic container includes for withdrawal of liquid goods at the lower side, approximately in mid-section in a side wall near its bottom a blown, calibrated tubular pipe for allowing attachment of a closeable discharge fitting which is fixedly welded with its tubular housing to the calibrated tubular pipe of the inner container. | 01-08-2009 |
20090152151 | PALLET CONTAINER, AND METHOD FOR PRODUCING AN ELECTROSTATICALLY NON-CHARGEABLE AND/OR ELECTRIC CHARGE-DRAINING PALLET CONTAINER - A pallet container includes a bottom pallet, a lattice frame, and a multilayer inner container made of thermoplastic material by a blow-molding technique and received in the lattice frame, for storing and transporting liquid fill material. The inner container has an exterior layer which is configured to be incapable of permanently retaining an electrostatic charge by allowing electric charges to be drained. The exterior layer contains an antistatic compound and has a layer thickness which does not or only insubstantially change a transparency or translucency of the exterior layer, allowing easy optical detection of a fill level of the liquid fill material in the container. The exterior layer includes a fusible, easily stretchable thermoplastic material (polymer). At least one of a center layer and an interior layer of the multilayer container includes a cold-impact-resistant HDPE material (High Density Polyethylene) with a high molecular weight. | 06-18-2009 |
20090269530 | Multilayer Plastic Container - A multilayer thermoplastic container for storing and transporting liquid contents, especially combustible or explosive contents, is made of at least three superimposed layers and includes at least one layer for discharging an electric charge. The innermost layer of the container in contact with the liquid content is made of virgin material. A second integrated inner layer which is covered by the innermost virgin material layer is electrically conductive as a result of incorporated additives, e.g. conductive carbon black and is covered on the outside by another electrically non-conductive layer. Electric charge carriers that accumulate on the surface of the thin inner layer due to the friction with the content are “suctioned through” large areas of the inner, electrically non-conductive layer by the second, electrically conductive layer and discharged. | 10-29-2009 |
20100200579 | PALLET CONTAINER - A pallet container for the storage and transport of liquid or free-flowing goods, includes a thin-walled inner container of thermoplastic material, a tubular lattice frame closely surrounding the inner plastic container in the form of a support jacket, and a bottom pallet upon which the inner plastic container rests and with which the tubular lattice frame is securely fixed. The inner plastic container includes for withdrawal of liquid goods at the lower side, approximately in mid-section in a side wall near its bottom a blown, calibrated tubular pipe for allowing attachment of a closeable discharge fitting which is fixedly welded with its tubular housing to the calibrated tubular pipe of the inner container. | 08-12-2010 |
20110180554 | PALLET CONTAINER - The present invention relates to a pallet container ( | 07-28-2011 |
20110266284 | LIDDED CONTAINER - The invention relates to a lidded container for storing and transporting in particular hazardous liquid fill goods, including an outer container body, an upper container lid and an inserted thin-walled inliner. The container lid has at least one filling and emptying opening that can be closed in a gas and liquid tight manner and that, for example, can be attached by means of a U-shaped tension ring closure or without tension ring as a snap cover by means of snap closure or a screw cap by means of screw closure on the upper container opening of the container body on a correspondingly designed flange edge. The thin-walled inliner ( | 11-03-2011 |
20120160729 | MULTILAYER PLASTIC CONTAINER - A multilayer thermoplastic container for storing and transporting liquid contents, especially combustible or explosive contents, is made of at least three superimposed layers and includes at least one layer for discharging an electric charge. The innermost layer of the container in contact with the liquid content is made of virgin material and a second integrated inner layer which is covered by the innermost virgin material layer is electrically conductive as a result of incorporated additives, e.g. conductive carbon black and is covered on the outside by another electrically non-conductive layer. Electric charge carriers that accumulate on the surface of the thin inner layer due to the friction with the content are “suctioned through” large areas of the inner, electrically non-conductive layer by the second, electrically conductive layer and discharged. | 06-28-2012 |
Klaus Peter Werner, Wijchen NL
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20100187449 | OPTICAL SENSOR MODULE AND ITS MANUFACTURE - The invention relates to an optical sensor module ( | 07-29-2010 |
20110116101 | LASER SELF-MIXING MEASURING DEVICE - A laser self-mixing measuring device is provided, comprising a laser with a laser cavity and a surface arranged along the optical path of the laser beam which redirects incident laser light back into the laser cavity. The surface comprises a periodic structure which diffracts the laser light into partial beams. | 05-19-2011 |
Klaus-Peter Bansemir, Langenfeld DE
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20100056642 | HEPATITIS A VIRICIDE - The invention relates to agents which combat the hepatitis A virus, containing only minimal amounts of chlorine-containing and/or chlorine cleaving active ingredients, or none of said substances. The inventions also relates to the use of these agents and to a method for their production. | 03-04-2010 |
20120087961 | HEPATITIS A VIRUCIDE - The invention relates to agents which combat the hepatitus A virus, containing only minimal amounts of chlorine-containing and/or chlorine cleaving active ingredients, or none of said substances. The inventions also relates to the use of these agents and to a method for their production. | 04-12-2012 |
Klaus-Peter Brhel, Philippsburg DE
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20120071899 | DEVICE AND METHOD FOR APPLYING A MEDICAL LOCKABLE CLIP IN A TISSUE AREA - A device and method are provided for clips or staples as an effective substitute for suture material when joining body tissue or covering body tissue with a mesh, such as is particularly used in fracture operations. The device for applying a medical lockable clip ( | 03-22-2012 |
Klaus-Peter Dimitrov-Kuhl, Hillsborough, NJ US
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20090046303 | PARAMETERIZED OPTICAL SYSTEM AND METHOD - A system for segmented parametric optimization of emissions from a light source, including a light source emitting light rays at a plurality of angles and an optic for directing light rays from the light source, the optic including at least one annular segment, the at least one annular segment being configured to optimize a characteristic of the emitted light rays, and a method for using and manufacturing the system. | 02-19-2009 |
Klaus-Peter Dörle, Mehlingen DE
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20100047054 | TURBOCHARGER - The invention relates to a turbocharger ( | 02-25-2010 |
Klaus-Peter Dörle, Mehlingen DE
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20100047054 | TURBOCHARGER - The invention relates to a turbocharger ( | 02-25-2010 |
Klaus-Peter Erickhoff, Wiedenbruck DE
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20140057772 | PHASE-SEPARATION METHOD FOR A PRODUCT, USING A CENTRIFUGE - A method for the continuous processing of a product such as a vegetable or animal oil or fat. The processing occurs via a separation into two liquid phases and a solid phase. The method step includes processing the product, the processing occurring in a centrifuge arranged as a separator, the separator including a rotatable drum, a disk stack having risers arranged in the drum, a product feed having a feed tube, a first separator disk to discharge a lighter liquid phase from the drum, a second separator disk to discharge a heavier liquid phase from the drum, and a solids discharge opening to discharge a solids phase from the drum. A separation zone is formed between the lighter phase and the heavier phase in the separator. | 02-27-2014 |
Klaus-Peter Galuschki, Berlin DE
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20110255769 | MACHINE PERFORMANCE TESTING METHOD AND DEVICE - A transparent panel is used to acquire a test sample from a machine to be tested; where the test sample includes at least one object placed on the transparent panel by the machine to be tested. A scanning device is used to scan the transparent panel to obtain image data and a computing device is used to determine the operation accuracy of the machine to be tested according to the image data from the scanning device. These devices may be used for machine performance testing and acquiring an image of the test sample. | 10-20-2011 |
20110262029 | System and method for detecting solder paste printing - A system and a method detect solder paste printing. The system includes a detecting device for detecting solder paste when a scraping blade pushes the solder paste to spread over a template to obtain information associated with the rolling speed of the solder paste, and a state-indicating device for generating a printing-state indication based on the information associated with the rolling speed of the solder paste. The method includes detecting the solder paste during rolling to obtain the information associated with the rolling speed of the solder paste, and generating a printing-state indication based on said information associated with the rolling speed of the solder paste. By detecting the solder paste during rolling to obtain the printing state, it is possible to monitor the printing state in real time, discover an abnormal condition in time, and reduce costs to the maximum extent. | 10-27-2011 |
Klaus-Peter Gerbling, Berlin DE
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20090186375 | Method for Determining Bioactivity of Molecules - The present invention relates to a method for determining activity of a molecule, wherein the molecule comprises at least two active parts, and wherein the first part is capable of modulating the activity of cells, and the second part can specifically bind to a target, and kits useful for performing the method. | 07-23-2009 |
Klaus-Peter Hoffmann, St. Ingbert DE
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20130305438 | PROTECTIVE SUIT FOR USE IN A COOLING CHAMBER - A protective suit ( | 11-21-2013 |
Klaus-Peter Hoffmann, Cuxhaven DE
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20120196249 | DENTAL TEMPORARY SUPERSTRUCTURES AND MATERIALS FOR PRODUCTION THEREOF AND CORRESPONDING METHODS - A dental material, a dental mixture or a dental multi-component system for making the material of or core for a temporary superstructure for a dental implant by polymerization hardening, consisting of one, two or a plurality of polymerizable (meth)acrylates, and optionally further constituents. The dental material, the dental mixture or the multi-component system is hardenable to a product, and the maximum compressive modulus is 420 MPa, and is used in therapeutic treatments for accelerating the osseointegration of dental implants, in particular according to the method of progressive bone loading. Also described are temporary superstructures and cores themselves, and a temporary dental prosthesis, a kit for making a plurality of temporary superstructures for a dental implant or a plurality of cores for temporary superstructures for a dental implant. A corresponding method of preparing a temporary superstructure or a core is also described. | 08-02-2012 |
20140138864 | KIT AND METHOD FOR INDIRECT CHAIRSIDE PRODUCTION OF COMPOSITE INLAYS - The present invention relates to a kit for indirect production of composite inlays, comprising a polymerizable material for production of a dental model, a polymerizable material for production of an inlay, a polymerizable material for luting of a crosslinked and non-sand-blasted, non-silanized, non-etched, non-primed and non-roughened composite inlay, the surfaces of which have been fully polymerized, in the cavity. Also disclosed is a polymerizable material for increasing the bond strength between the polymerizable material for luting of a crosslinked non-sand-blasted, non-silanized, non-etched, non-primed and non-roughened composite inlay, the surfaces of which have been fully polymerized, in the cavity, and the hard substance of the tooth, and an acid solution for surface etching of the hard substance of the tooth. The invention further relates to methods for producing a composite inlay. | 05-22-2014 |
Klaus-Peter Hofmann, Berlin DE
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20140058936 | MANAGING VIRTUAL WALLETS PROVIDED BY A MOBILE TERMINAL - A method for managing a plurality of virtual wallets provided by a mobile terminal for carrying out transactions with electronic devices. The plurality of virtual wallets receives different virtual objects and manages resources available via the different virtual objects. Each virtual wallet of the plurality of virtual wallets includes a respective security element connected to the mobile terminal used for identification in a transaction and a respective wallet application for controlling transactions and providing a user interface for a user of the mobile terminal. The plurality of virtual wallets are linked and displayed by a unitary wallet application. The method includes accessing, by the unitary wallet application, a security element of a virtual wallet for a transaction via a hardware control interface supported by the mobile terminal that is universal to the respective security elements of the plurality of virtual wallets. | 02-27-2014 |
Klaus-Peter Jaquemotte, Westerstede DE
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20130064675 | WIND TURBINE ROTOR BLADE - The invention concerns a wind power installation rotor blade. The rotor blade has a rotor blade root, a rotor blade tip, a rotor blade leading edge and a rotor blade trailing edge. The rotor blade further has a pressure side and a suction side as well as at least one web at least partially between the suction and pressure sides. The rotor blade has a longitudinal direction between the rotor blade root and the rotor blade tip. The web is of a wave-shaped configuration in the longitudinal direction of the rotor blade. | 03-14-2013 |
Klaus-Peter Jurkat, Berlin DE
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20130342922 | MEDICAL MAGNIFICATION DEVICE - The invention relates to a medical magnification device which has an optical unit with an optical axis, illuminating means and attachment elements, wherein the optical unit has at the proximal end, an eyepiece of monocular design, and the illuminating means is configured in the form of a hollow cylinder, is connected at a distal end to the optical unit and is coaxial with respect to the optical axis generating a concentric illumination pattern and the attachment elements include means that can be connected to the optical unit and that are configured so that the optical unit is adjustable in any direction. | 12-26-2013 |
Klaus-Peter Koch, Weingarten DE
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20090128375 | Control Apparatus Having at Least One Pushbutton Switch and Domestic Appliance Having a Control Apparatus - A control apparatus having at least one pushbutton switch can be used, for example, in a control panel of an electronic domestic appliance. The control apparatus includes a mount element, a piezo-film having at least one sensor field corresponding to the at least one pushbutton switch, a first adhesive layer connecting the piezo-film to the mount element, a cover layer facing a user side, a second adhesive layer connecting the cover layer to the piezo-film, and at least one attachment element for attachment of the control apparatus to the control panel. An electronic domestic appliance having a control apparatus is also provided. | 05-21-2009 |
Klaus-Peter Kuenkele, Marzling DE
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20120237506 | Antigen Binding Proteins - The present invention relates to antigen binding proteins comprising two Fc parts, methods for their production, pharmaceutical compositions containing said antigen binding proteins, and uses thereof. | 09-20-2012 |
20120237507 | Monovalent Antigen Binding Proteins - The present invention relates to monovalent antigen binding proteins with a CH1-CL domain exchange, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 09-20-2012 |
20130217623 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 08-22-2013 |
20150099699 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 04-09-2015 |
Klaus-Peter Kuenkele, Benediktbeuern DE
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20080226635 | Antibodies against insulin-like growth factor I receptor and uses thereof - An antibody binding to IGF-IR and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is between 20% and 50%, has improved properties in antitumor therapy. | 09-18-2008 |
20090275126 | ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR AND USES THEREOF - Antibodies against insulin like growth factor I receptor (IGF-IR), methods for their production, pharmaceutical compositions containing said antibodies, and uses for such antibodies are disclosed. Such antibodies are implicated in antitumor therapy. | 11-05-2009 |
20100081796 | BISPECIFIC ANTI-EGFR/ANTI-IGF-1R ANTIBODIES - The present invention relates to bispecific antibodies against EGFR and against IGF-1R, methods for their production, pharmaceutical compositions containing said antibodies, and methods of treatment using the antibodies. | 04-01-2010 |
20100322927 | GLYCOSYLATED ANTIBODIES - The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof. | 12-23-2010 |
20100323373 | METHOD FOR THE ASSESSMENT OF THE INHIBITORY ACTIVITY OF ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR - A method for the assessment of the inhibitory activity of an antibody for inhibiting the binding of IGF-1 and/or IGF-2 to IGF-1R in a lysed PBL sample of a mammal which has been treated with said antibody, characterized in that the IGF-1R protein level of said PBLs is measured as a measure for the inhibitory activity of said antibody. | 12-23-2010 |
20110009317 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 01-13-2011 |
20120076778 | Antibodies Against Insulin-Like Growth Factor I Receptor and Uses Thereof - An antibody binding to IGF-IR and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is between 20% and 50%, has improved properties in antitumor therapy. | 03-29-2012 |
20120128664 | GLYCOSYLATED ANTIBODIES - The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof. | 05-24-2012 |
20120149879 | BISPECIFIC ANTI-EGFR/ANTI-IGF-1R ANTIBODIES - The present invention relates to bispecific antibodies against EGFR and against IGF-1R, methods for their production, pharmaceutical compositions containing said antibodies, and methods of treatment using the antibodies. | 06-14-2012 |
20120322732 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 12-20-2012 |
20140193404 | GLYCOSYLATED ANTIBODIES - The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof. | 07-10-2014 |
Klaus-Peter Lang, Bad-Waldsee DE
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20110142553 | CONVEYOR DEVICE FOR PNEUMATICALLY CONVEYING BULK MATERIAL - A conveyor device is used for the pneumatic conveying of bulk material. The conveyor device has a main conveyor pipe and a plurality of bypass conveyor pipe sections which are separate from one another and arranged one behind the other within the latter. The main extent direction of the bypass conveyor pipe sections runs along the main conveyor pipe. The bypass conveyor pipe sections in each case have an inlet opening and an outlet opening for conveyor gas. The inlet opening, when the main conveyor pipe is horizontally installed, is arranged in a cross sectional portion of the main conveyor pipe, which is located above a cross sectional portion of the main conveyor pipe, in which the outlet opening is arranged. The result is a conveyor device, of which the efficiency, in other words the ratio of the conveying power and the conveyor gas quantity used, is improved. | 06-16-2011 |
20130170926 | LOADING SYSTEM FOR LOADING BULK MATERIAL FROM A BULK MATERIAL PRODUCTION PLANT ONTO A SHIP AND UNLOADING SYSTEM FOR LOADING BULK MATERIAL FROM A SHIP ONTO TRANSPORTERS - A loading system for loading bulk material from a bulk material production plant onto a ship has at least one stationary intermediate storage container for receiving the bulk material from the bulk material production plant. A first loading conveying device is used to convey the bulk material from the bulk material production plant into the intermediate storage container. A second loading conveying device is used to convey the bulk material from the intermediate storage container into the ship. An unloading system for loading bulk material from a ship onto transporters has a stationary intermediate storage container for receiving the bulk material from the ship. Two unloading conveying devices are used to convey the bulk material, from the ship into the intermediate storage container and, from the intermediate storage container into the transporters. | 07-04-2013 |
Klaus-Peter Lang, Brackenheim-Botenheim DE
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20100153468 | CONFIGURATION CHANGE WITHOUT DISRUPTION OF INCOMPLETE PROCESSES - Various embodiments include one or more of systems, methods, software, and data structures to provide flexibility when configuring systems to new or different processes while not disrupting incomplete processes. Some embodiments include receiving input representative of a configuration change to at least one configuration setting and storing a copy of a setting of the at least one configuration setting from a current configuration to an historical configuration setting storage location. Such embodiments may further include storing the input representative of the configuration change into the current configuration. Following such configuring processes already initiated may be completed according to the copied historical configuration setting and new processes may be initiated according to the new configuration setting. These and other embodiments are described herein. | 06-17-2010 |
Klaus-Peter Lang, Brackenheim DE
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20100281243 | Configuring Computer Systems with Business Configuration Information - A configuration server includes a configuration repository that stores a wide range of configuration information for possible use by application programs. The configuration repository may include configuration parameters, settings for the parameters, and meta-data of definitions and descriptions of the parameters. Configuration information is selected from the configuration repository and stored in a configuration directory for later use by application programs at runtime. The configuration information is accessed from the configuration directory when needed by an application program or a component thereof. | 11-04-2010 |
20100281244 | Configuring Computer Systems with Business Configuration Information - A configuration server includes a configuration repository that stores a wide range of configuration information for possible use by application programs. The configuration repository may include configuration parameters, settings for the parameters, and meta-data of definitions and descriptions of the parameters. Configuration information is selected from the configuration repository and stored in a configuration directory for later use by application programs at runtime. The configuration information is accessed from the configuration directory when needed by an application program or a component thereof. | 11-04-2010 |
20100287075 | Configuring Computer Systems with Business Configuration Information - A configuration server includes a configuration repository that stores a wide range of configuration information for possible use by application programs. The configuration repository may include configuration parameters, settings for the parameters, and meta-data of definitions and descriptions of the parameters. Configuration information is selected from the configuration repository and stored in a configuration directory for later use by application programs at runtime. The configuration information is accessed from the configuration directory when needed by an application program or a component thereof. | 11-11-2010 |
Klaus-Peter Lebkuecher, Lengerich DE
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20100282412 | METHOD OF MAKING A PROTECTIVE FILM - A protective film is made by extruding a molten-plastic film from a slit nozzle into a nip formed between an outer face of a rotatable roll and a face of a metal belt. One of these faces is smooth. The belt is tensioned to press the film in the nip between the belt and the roll outer face. The belt or the roll is cooled to harden the film such that one face of the film engaging the smooth face of the roll or belt is rendered smooth and free of defects. | 11-11-2010 |
Klaus-Peter Linzmaier, Winterbach DE
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20100188070 | METHOD AND DEVICE FOR MEASURING A LEVEL OF AN ELECTRIC MEASUREMENT VARIABLE THAT CAN BE CHANGED OVER TIME - A method measures a level of an electric measurement variable that can be changed over time, particularly an electric voltage or an electric current. A measurement signal of the measurement variable is differentiated and a current amplitude value of the differentiated measurement variable is determined. Through the iterative approximation of a comparison value to the current amplitude value a level value of the measurement variable is determined. | 07-29-2010 |
20110197514 | CONTROLLER FOR PLATFORM DOORS - A method and a system control platform doors that are disposed at a distance to each other corresponding to a train to be entered via the platform. In order to actuate platform doors in a simple manner such that the door system of a platform is highly available, the platform doors are divided into a plural number of groups, that adjacent platform doors are associated with different groups. Each group may be connected to at least two controllers via one respective transfer medium, that control signals of at least one controller are transferred to the platform doors via the transfer media, such that in case of failure of one controller, the functions of the failed controller are transferred to the at least second controller. | 08-18-2011 |
Klaus-Peter Meier, Stammham DE
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20080305722 | Method for the single-sided polishing of bare semiconductor wafers - Single-sided polishing of bare semiconductor wafers is accomplished by using a polishing head with a membrane made of a resilient material by which polishing pressure is transmitted onto the backside of the semiconductor wafer to be polished, wherein the semiconductor wafer is pressed against a polishing cloth with a smooth surface while supplying a polishing agent, and is prevented from sliding off the membrane by a retainer ring. The retainer ring is provided with channels on a side surface facing the polishing cloth. | 12-11-2008 |
Klaus-Peter Mollhagen, Memmingen DE
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20080246241 | Axle suspension for heavy vehicles - The present invention relates to an axle suspension for heavy vehicles, in particular trucks, comprising an axle beam which bears axle parts projecting over at oppositely disposed sides, each axle part preferably bearing a wheel drive; an axle beam bearing which permits upward and downward movements of the axle beam as well as pendular movements of the axle beam around a substantially lying pendular axis transverse to the longitudinal direction of the axle parts; a spring device for the resilient support of the upward and downward movements of the axle beam at a vehicle frame; and also a pendular damping device for the damping of the pendular movements of the axle beam. The invention is characterized in that the pendular damping device has a rotary axle which is pivoted to a part connected to the vehicle frame and drives a damping lever rotatably pivoted to the axle beam in a rotary manner on pendular movements of the axle beam, said damping lever acting on at least one damping element fastened to the axle beam. | 10-09-2008 |
20080291772 | Building material mixer - The present invention relates to a building material mixer having a mixer drum which can be rotationally driven by a mixer drive, with the mixer drum being rotatably supported by the mixer drive at a mixer frame part, in particular a traveling gear frame part, at one of its end face ends and with the mixer drive having a drive part, in particular a hydraulic motor, and a drive transmission connected to the mixer drum. In accordance with the invention, the building material mixer is characterized in that the mixer drive is movably supported by movable bearing means at the mixer frame part allowing tilting movements; and in that the mixer drum is fastened to the transmission housing of the drive transmission. | 11-27-2008 |
Klaus-Peter Paulat, Schwendi DE
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20110011230 | DEVICE FOR PRODUCING A HOLE IN A SHEET-SHAPED MATERIAL - In a device ( | 01-20-2011 |
Klaus-Peter Saeck, Detmold DE
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20100103567 | Circuit arrangement for protecting electronic devices against incorrect logic voltages - The invention is based on the problem of devising a circuit arrangement ( | 04-29-2010 |
Klaus-Peter Schulz, Auggen DE
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20130327630 | THERMAL REACTOR - A thermal reactor for the continuous thermolytic recycling of granules of scrap tires, vulcanization residues and waste plastics, and of similar products features a feed portion, a central heating-zone portion and a discharge portion arranged vertically one below the other. An extraction pipe is located centrally in the central heating-zone portion of the thermal reactor, the lateral surface of the extraction pipe featuring numerous holes and/or slits for withdrawal of the vaporized short-chain hydrocarbon compounds being formed, and the extraction pipe having conical bells pushed onto it one above the other. A device withdraws the vaporized hydrocarbon compounds from the extraction pipe. Radially arranged heating plates are provided on the lateral surface of the reactor in its central heating-zone portion, the heating plates being arranged at the heating levels, which lie one above the other, such that the plates are mutually offset. | 12-12-2013 |
Klaus-Peter Sprol, Kempten DE
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20150049969 | Radial Bearing - The invention relates to a radial bearing, comprising a housing, a housing bore extending along a bearing axis, several tilting segments that are arranged around the bearing axis in order to support a shaft and each have a radially outer bearing surface, by means of which the tilting segments are supported on a supporting surface on the housing. The radially outer bearing surface of each tilting segment and the supporting surface are arranged facing each other. Each tilting segment is movably arranged relative to the housing. The invention is characterized by the following features: a first one of the surfaces forms a first section curve with a first section plane perpendicular to the bearing axis; the first section curve is convexly curved and has a first main radius of curvature, and the second surface forms a second section curve with the section plane perpendicular to the bearing axis; the second section curve is correspondingly concavely curved and has a second main radius of curvature, wherein the magnitude of the first main radius of curvature of the first surface is smaller than the magnitude of the second main radius of curvature of the second surface; the first surface forms a third section curve with a second section plane parallel to the bearing axis; the third section curve is convexly curved and has a first secondary radius of curvature, and the second surface forms a fourth section curve with the second section plane parallel to the bearing axis; and the fourth section curve is correspondingly concavely curved or not curved and has a second secondary radius of curvature or correspondingly has no curvature, the two secondary radii of curvature being different from each other. | 02-19-2015 |
Klaus-Peter Weiss, Pirna DE
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20090239156 | Apparatus and Method for the Removal of Pellicles from Masks - An apparatus and a method for the removal of pellicles from masks which can be used for photolithographic purposes. The pellicles are removed from masks in a universal manner without them being further contaminated or damaged. In an apparatus, at least one grip is present for the manipulation of masks provided with pellicles which has at least two fixing elements which engage at the edge of a mask with exerted pressure force. There are moreover present in this connection at least one detector for the contactless determination of the position of mounts formed at the radially outer edge of pellicles, and a heating device for the heating of an adhesive with which pellicles are fastened to a mask with material continuity, and a removal apparatus of the pellicles from a mask having a mask fixing unit and a pellicle removal unit. | 09-24-2009 |
Klaus-Peter Zeffler, Darmstadt DE
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20090285373 | METHOD FOR USING DIGITAL DATA NETWORKS FOR THE TRANSMISSION OF DATA VIA VOICE CONNECTION PATHS - A method for reducing bandwidth when transmitting data between a sending terminal and a receiving terminal over a voice connection path using a digital data network. The coding of user information is converted within the digital data network between data transmission in the voice connection path and data transmission in the digital data network so that the user information is transmitted on one section of the digital data network via the coded voice connection path and the user information is transmitted on another section of the digital data network using a method suitable for the digital data network. | 11-19-2009 |
Klaus-Peter Ziock, Clinton, TN US
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20080203316 | Dual-sided coded-aperture imager - In a vehicle, a single detector plane simultaneously measures radiation coming through two coded-aperture masks, one on either side of the detector. To determine which side of the vehicle a source is, the two shadow masks are inverses of each other, i.e., one is a mask and the other is the anti-mask. All of the data that is collected is processed through two versions of an image reconstruction algorithm. One treats the data as if it were obtained through the mask, the other as though the data is obtained through the anti-mask. | 08-28-2008 |
20110024611 | CALIBRATION METHOD FOR VIDEO AND RADIATION IMAGERS - The relationship between the high energy radiation imager pixel (HERIP) coordinate and real-world x-coordinate is determined by a least square fit between the HERIP x-coordinate and the measured real-world x-coordinates of calibration markers that emit high energy radiation imager and reflect visible light. Upon calibration, a high energy radiation imager pixel position may be determined based on a real-world coordinate of a moving vehicle. Further, a scale parameter for said high energy radiation imager may be determined based on the real-world coordinate. The scale parameter depends on the y-coordinate of the moving vehicle as provided by a visible light camera. The high energy radiation imager may be employed to detect radiation from moving vehicles in multiple lanes, which correspondingly have different distances to the high energy radiation imager. | 02-03-2011 |
20110025841 | ESTIMATING VEHICLE HEIGHT USING HOMOGRAPHIC PROJECTIONS - Multiple homography transformations corresponding to different heights are generated in the field of view. A group of salient points within a common estimated height range is identified in a time series of video images of a moving object. Inter-salient point distances are measured for the group of salient points under the multiple homography transformations corresponding to the different heights. Variations in the inter-salient point distances under the multiple homography transformations are compared. The height of the group of salient points is estimated to be the height corresponding to the homography transformation that minimizes the variations. | 02-03-2011 |