Patent application number | Description | Published |
20080207913 | Poly(ethylene glycol) containing chemically disparate endgroups - The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof. | 08-28-2008 |
20080274173 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 11-06-2008 |
20080274965 | ENCAPSULATED AMYLOID-BETA PEPTIDES - The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof. | 11-06-2008 |
20090092554 | ENCAPSULATED CONTRAST AGENTS - The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same. | 04-09-2009 |
20090110662 | MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER - The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same. | 04-30-2009 |
20090286938 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS - The present invention provides polymerization initiators and uses thereof. | 11-19-2009 |
20100136063 | Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides - The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof. | 06-03-2010 |
20100159020 | POLYMERIC MICELLES FOR DRUG DELIVERY - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 06-24-2010 |
20100160645 | POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS - The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof. | 06-24-2010 |
20100278927 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 11-04-2010 |
20100278928 | POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER - The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 11-04-2010 |
20100278932 | POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER - The present invention provides micelles having SN-38 encapsulated therein. | 11-04-2010 |
20100280252 | POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS - The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof. | 11-04-2010 |
20100292432 | POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides block copolymers comprising hydrophobic moieties in a cationic complexing block, methods of preparing the same, and intermediates thereto. The compounds are useful in a variety of applications such as the assembly of micellar polyion complexes. The invention further provides methods of using said compounds and compositions thereof. | 11-18-2010 |
20100324259 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 12-23-2010 |
20110091534 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 04-21-2011 |
20110092668 | AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 04-21-2011 |
20110124840 | Synthesis of Homopolymers and Block Copolymers - The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same. | 05-26-2011 |
20110142886 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 06-16-2011 |
20110142950 | POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER - The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 06-16-2011 |
20110224383 | POLY(ETHYLENE GLYCOL) DERIVATIVES FOR METAL-FREE CLICK CHEMISTRY - The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof. | 09-15-2011 |
20110229528 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 09-22-2011 |
20110256227 | CONTROLLED POLYPLEX ASSEMBLY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, polyplexes comprising polycations, polyanions, and polynucleotides are provided. The invention further provides methods of making and using said polyplexes. | 10-20-2011 |
20120046735 | PLASMA MODIFICATION OF METAL SURFACES - The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials. | 02-23-2012 |
20120046757 | COVALENT MODIFICATION OF METAL SURFACES - The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials. | 02-23-2012 |
20120148631 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 06-14-2012 |
20120196989 | SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS - The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same. | 08-02-2012 |
20120226050 | POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS - The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof. | 09-06-2012 |
20130195987 | POLYMERIC MICELLES FOR DRUG DELIVERY - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. | 08-01-2013 |
20130266617 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION - The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 10-10-2013 |
20130309277 | POLYMER MICELLES CONTAINING ANTHRACYCLINES FOR THE TREATMENT OF CANCER - The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof. | 11-21-2013 |
20130310912 | COVALENT MODIFICATION OF METAL SURFACES - The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials. | 11-21-2013 |
20130344117 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY - The present invention provides polymers, compositions thereof, and polyplexes comprising said polymers. In particular, cationic polymers, pegylated versions thereof, and polynucleotide containing polyplexes comprising such polymers are provided. The invention further provides methods of using said polymers and polyplexes. | 12-26-2013 |
20140112873 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE - The subject invention pertains to a modified MC1R peptide ligand comprising a peptide that is a melanocortin 1 receptor (MC1R) ligand and a functionality or linker, such as a click functionality, for conjugation to a surface or agent. The modified MC1R peptide ligand can be coupled, e.g., via a click reaction with a complementary click functionality attached, to a moiety to form an MC1R-targeted agent. Drugs, contrast agents, polymers, particles, micelles, surfaces of larger structures, or other moieties can be targeted to the MC1R. The subject invention also pertains to a MC1R peptide ligand-micelle complex comprising a peptide that is a melanocortin 1 receptor ligand connected via a click reaction product to a micelle. The micelle is stable in vivo and can target melanoma tumor cells by association of the peptide ligand with the MC1R or the tumor and selectively provide a detectable and/or therapeutic agent (such as an imageable contrast agent and/or anti-cancer agent) selectively to the tumor cell. | 04-24-2014 |
20140170225 | IMMUNOTHERAPY FOR TREATMENT OF AMYLOID-RELATED DISORDERS USING ENCAPSULATED BETA-AMYLOID PEPTIDES - The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof. | 06-19-2014 |