Kellum, Jr.
John A. Kellum, Jr., Pittsburgh, PA US
Patent application number | Description | Published |
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20080281248 | REMOVAL OF CONTRAST AGENTS FROM BLOOD - The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent. | 11-13-2008 |
20120077690 | BIOMARKERS OF RENAL INJURY - This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor β1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury. | 03-29-2012 |
20150241415 | EVALUATING RENAL INJURY USING HYALURONIC ACID - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in sepsis patients. In particular, the invention relates to using assays that detect hyaluronic acid as diagnostic and prognostic biomarker assays of renal injury in the sepsis patient. | 08-27-2015 |
John A. Kellum, Jr., Pittsburg, PA US
Patent application number | Description | Published |
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20130323751 | Urine Biomarkers For Prediction Of Recovery After Acute Kidney Injury: Proteomics - This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, renal recovery. For example, renal recovery can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring urinary proteins can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury. Alternatively, the invention describes signature protein expression profiles to establish the probability of renal to recovery and/or renal non-recovery. | 12-05-2013 |
John Alston Kellum, Jr., Pittsburgh, PA US
Patent application number | Description | Published |
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20150335807 | REMOVAL OF CARBON DIOXIDE VIA DIALYSIS - A method of reducing the concentration of carbon dioxide in blood plasma includes removing blood from a patient and treating or processing at least blood plasma of the blood by flowing the blood plasma on one side of at least one semi-permeable membrane and flowing a dialysate on the other side of the at least one semi-permeable membrane. The dialysate has a concentration of bicarbonate less than the concentration of bicarbonate in the blood plasma before treating the blood plasma and has a composition such that the blood plasma strong ion difference that results from treating the blood plasma in conjunction with an achieved reduction in blood plasma CO2 concentration results in a blood plasma pH that does not change by more than +/−0.5 during treatment. | 11-26-2015 |