Kee, US
Bill Kee, San Francisco, CA US
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20130080342 | Preservation of Documents in a Hosted User Environment - Organizations struggle to meet their obligation to preserve electronic documents when litigation occurs or is likely. This is particularly challenging in a hosted user environment using a distributed file system. Embodiments of the invention enable a user to preserve email, chats, text documents, and other electronic files in the native storage systems of these applications, or in a hosted eDiscovery archive that syncs with the native store. In an embodiment, the process uses a label to indicate that a particular document should not be deleted. When purging tasks occur, the documents with such labels are exempt from purging until the label is removed. Search queries may also be run on the documents in their native locations to identify those relevant to a litigation hold. Because the system operates on the native document store, a user is not required to create a copy of the document in order to preserve it. | 03-28-2013 |
Christopher M. Kee, Glendora, CA US
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20110094686 | HYBRID ENCLOSURE SYSTEM - A hybrid enclosure, comprising a flexible, lightweight cover coupled within a rigid frame and at least one rigid stile that functions to confine a space, with minimal structural encroachment into potential ingress and egress area of the space when fully open. | 04-28-2011 |
Christopher Marshal Kee, Glendora, CA US
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20110005140 | ARTICULATING ROLLER ARM ASSEMBLY - An articulating roller arm assembly comprising a single integral piece cantilever beam with a span section and a throw section, with the span section oriented substantially transverse the throw section. A first distal end of the throw section and a distal end of the span section form a bend of the single integral piece cantilever beam. The articulating roller arm assembly further including a first wheel that is coupled with a first distal end of the throw section, and a second wheel that is coupled with a second distal end of the throw section. | 01-13-2011 |
20130019396 | ENCLOSURE SYSTEMS - An enclosure, comprising a sill that includes a drainage system having a spill channel that has a first barrier and a second barrier, with the second barrier positioned below the spill channel and facing a lower distal end of an exterior side of a stationary panel. The enclosure further provides set of hinge and distal rollers for maximum articulation of non-stationary panels without much encroachment into a closed space. | 01-24-2013 |
Daniel E. Kee, Somerville, MA US
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20080276408 | AUTONOMOUS COVERAGE ROBOT - A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface. | 11-13-2008 |
20080281470 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 11-13-2008 |
20120265343 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 10-18-2012 |
20120265346 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 10-18-2012 |
20140215735 | AUTONOMOUS COVERAGE ROBOT - A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface. | 08-07-2014 |
Eric Kee, Hanover, NH US
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20130129234 | Perceptual Rating Of Digital Image Retouching - A method is provided for automatically providing a digital image rating of photo retouching. The method includes the step of receiving at a computer, including a processor, a first set of pixel data of an original image and a second set of pixel data of a retouched image. The method also includes using the processor to determine a plurality of geometric statistics and a plurality of photometric statistics from the first and second sets of pixel data. The method further includes the step of using the processor to quantify a rating of the retouched image based upon the geometric statistics and photometric statistics to indicate deviation of the retouched image from the original image. A system is also provided to perform the steps. | 05-23-2013 |
20140321696 | Perceptual Rating Of Digital Image Retouching - A method is provided for automatically providing a digital image rating of photo retouching. The method includes the step of receiving at a computer, including a processor, a first set of pixel data of an original image and a second set of pixel data of a retouched image. The method also includes using the processor to determine a plurality of geometric statistics and a plurality of photometric statistics from the first and second sets of pixel data. The method further includes the step of using the processor to quantify a rating of the retouched image based upon the geometric statistics and photometric statistics to indicate deviation of the retouched image from the original image. A system is also provided to perform the steps. | 10-30-2014 |
Eric R. Kee, Hanover, NH US
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20130132044 | Lens Modeling - Techniques are disclosed relating to lens modeling. In one embodiment, a lens model may be generated based on reference images of a pre-determined, known geometric pattern. The lens model may represent a spatially variant blur pattern across the image field of the lens used to capture the reference images. In one embodiment, the lens model may include Gaussian approximations of the blur that may minimize the difference between a location within a reference image and a corresponding location of a pre-determined, known geometric pattern. In one embodiment, the generated lens model may be applied to deblur a new image. | 05-23-2013 |
Hojin Kee, Austin, TX US
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20130247019 | Specifying Memory Resource Implementations for Deployment of a Graphical Program to Programmable Hardware - System and method for managing and specifying hardware implementation of a graphical program. A graphical program that implements an algorithm is stored in a memory of a computer system. The graphical program meets one or more first specified implementation requirements and is targeted for deployment to a programmable hardware element. A plurality of sets of descriptive directives are also stored in the memory, where the descriptive directives are associated with the graphical program and specify one or more additional specified implementation requirements, e.g., memory resource implementations, optimization directives, and so forth, where the additional directives result from programmatic and/or user-specification. Each set of descriptive directives is useable by a synthesis tool to generate a respective hardware configuration program for deployment to the graphical programmable hardware element. | 09-19-2013 |
20140059524 | Compile Time Execution - When compiling high level, graphical code (e.g. LabVIEW™ code) representative of a design, parts of the code that do not depend on external input data may be executed during the compilation process. Specific variables and/or value traces of specific variables in the program, e.g. constant values and/or repeating patterns may be recorded then analyzed, and certain transformations may be applied in the compilation process according to the results of the analysis, thereby optimizing the design. In one approach, the graph may be dynamically stepped through one node at a time, and it may be determined whether all inputs to the stepped-through node are known. If those inputs are known, type conversion and the operation corresponding to the stepped-through node may be dynamically performed. In another approach, a subset of the graphical code not depending on external data may be compiled and executed, thereby obtaining the same results as described above. | 02-27-2014 |
20150242193 | Program Optimization via Compile Time Execution - When compiling high level, graphical code (e.g. LabVIEW™ code) representative of a design, parts of the code that do not depend on external input data may be executed during the compilation process. Specific variables and/or value traces of specific variables in the program, e.g. constant values and/or repeating patterns may be recorded then analyzed, and certain transformations may be applied in the compilation process according to the results of the analysis, thereby optimizing the design. In one approach, the graph may be dynamically stepped through one node at a time, and it may be determined whether all inputs to the stepped-through node are known. If those inputs are known, type conversion and the operation corresponding to the stepped-through node may be dynamically performed. In another approach, a subset of the graphical code not depending on external data may be compiled and executed, thereby obtaining the same results as described above. | 08-27-2015 |
Howard Kee, Brambleton, VA US
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20130179960 | METHOD OF COLLABORATIVE COMPUTING - A system and method for allowing for distributed interaction in a computing scenario is presented. The system is powered by SandTable software. First and Second items are respectively displayed on interactive screens of first and second surface computers. A first token is configured to be placed on the interactive screen of one of the computers and that computers reads its credentials. The SandTable software determines a first access level of the first token based on the credentials of the first token when it is placed on the surface computer. The first surface computer displays an image of an add item symbol when the first token is authenticated as a valid token. The SandTable software is configured to detect when the add item symbol is selected and to generate a menu of new items. SandTable creates a new item based on the new item selected from the menu. | 07-11-2013 |
Jeanette M. Kee, Rockville, MD US
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20090276520 | METHOD AND APPARATUS FOR SERVER ELECTION, DISCOVERY AND SELECTION IN MOBILE AD HOC NETWORKS - A method and apparatus for server election, discovery and selection in mobile ad hoc communication networks is disclosed. The server election method may include a server node that may elect itself as a server in network if the received server capabilities, network server lists and network specific parameters allow its election as a server in the network. A client node may discover and select a server in the network by transmitting a server discovery request to a plurality of nodes in the network, receiving advertisements from one or more servers in the network in response to the server discovery request, and selecting a server based on the received stability and connectivity information for each server from which advertisements are received. | 11-05-2009 |
Jimmy Kee, San Diego, CA US
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20150115061 | GIMBAL PIN FOR JET PROPULSION SYSTEM - A thrust reverser actuator gimbal assembly for mounting a thrust reverser actuator to fixed structure of the thrust reverser is disclosed. The thrust reverser actuator gimbal assembly may comprise a gimbal, first and second gimbal pins mounted to the gimbal and defining a first pivot axis, the first and second gimbal pins adapted to form a pivotal joint with the fixed structure of the thrust reverser, third and fourth gimbal pins mounted to the gimbal and defining a second pivot axis normal to the first pivot axis, the third and fourth gimbal pins adapted to farm a pivotal joint with the thrust reverser actuator, wherein the first and second gimbal pins each include a shaft and a flange integrally formed together, the flange including a pair of bores for receiving a fastener to fasten the respective gimbal pin to the thrust reverser fixed structure. | 04-30-2015 |
Jung-Min Kee, New York, NY US
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20090187046 | Process to Produce Prostratin and Structural or Functional Analogs Thereof - This invention concerns a process to convert a hydroxyl group (bold in R | 07-23-2009 |
20120101283 | Prostratin and Structural or Functional Analogs Thereof - This invention concerns product and process to convert a hydroxyl group (bold in R | 04-26-2012 |
Jung-Min Kee, Plainsboro, NJ US
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20130260398 | PHOSPHOHISTIDINE ANALOGS - The present invention relates to the phosphohistidine analogs of the present invention which of the formula (I) and the hapten containing the residue of same. It also relates to the hapten conjugated to a carrier molecule and the isolated antibodies raised against the immunogens, said antibodies recognizing polypeptide containing a phosphorylated histidine or the phosphotriazole residue but it does not recognize an amino acid or polypeptide that is not phosphorylated or a polypeptide which is phosphorylated on amino acids other than histidine but not on histidine. | 10-03-2013 |
20150344589 | PHOSPHOHISTIDINE ANALOGS - The present invention relates to the phosphohistidine analogs of the present invention which of the formula | 12-03-2015 |
Kevin D. Kee, Somerville, MA US
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20140220119 | Capsules Containing High Doses of Levodopa for Pulmonary Use - The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L. The invention further provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L wherein the capsule material comprises hydroxypropylmethylcellulose (HPMC) and titanium dioxide. | 08-07-2014 |
20150320711 | Capsules Containing High Doses of Levodopa for Pulmonary Use - The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L. The invention further provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L wherein the capsule material comprises hydroxypropylmethylcellulose (HPMC) and titanium dioxide. | 11-12-2015 |
Kok-Hiong Kee, St. Louis, MO US
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20100301250 | REVERSIBLE FLOW VALVE ASSEMBLY - A flow valve is provided that comprises a valve chamber including first and second valve port openings in communication with first and second inlet/outlets. The valve further includes a shaft rotatably disposed in the valve chamber, and a first valve plate rotatably coupled to the shaft that is disposed in the valve chamber over the first valve port opening. The first valve plate has a first tapered slot positioned therein so as to align with the first valve port opening. The first valve plate is configured to rotate from its closed position covering the first valve port opening to an open position, where rotation of the first valve plate adjustably positions a wider or narrower portion of the first tapered slot over the first valve port opening. The valve further includes a second valve plate that is configured to rotate with the first valve plate, and to cover the second valve port opening. | 12-02-2010 |
20120080102 | Reversible Flow Valve Assembly - A valve is provided that comprises a valve chamber including first and second valve port openings in communication with first and second inlet/outlets, respectively. A shaft is rotatably disposed in the valve chamber. A first valve plate is rotatably coupled to the shaft that is disposed in the valve chamber over the first valve port opening. The first valve plate has a first opening positioned so as to align with the first valve port opening. The first valve plate is configured to rotate from its closed position covering the first valve port opening to an open position, where rotation of the first valve plate adjustably positions at least a portion of the first opening over the first valve port opening. A second valve plate is configured to rotate with the first valve plate, and to cover the second valve port opening. | 04-05-2012 |
Laura Alaina Kee, Madison, AL US
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20140155161 | Image Rendering Systems and Methods - The present disclosure is a gaming system that has a gaming module that generates and renders gaming image data to a display device and a communication module that generates viewport image data. Additionally, the gaming system has logic that intercepts a rendering operation of the gaming module and determines a location of the gaming image data. Further, the logic further generates combined image data by combining the gaming image data with the viewport image data and performs a rendering operation for display of the combined image data to the display device. | 06-05-2014 |
Martin J. Kee, Sammamish, WA US
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20080288802 | METHOD AND APPARATUS FOR OPERATING AN ELECTRONIC DEVICE IN A LOW POWER MODE - An electronic device, such as a hand-held portable computer, is provided with capability to operate an application during a low power mode. During the low power mode, portions of hardware, software, services, and/or other components of the portable computer that are not necessary to the operation of the application is suspended or otherwise deactivated. As each task is performed by the application, the components that are no longer needed for subsequent tasks to be performed by the application are also deactivated and reactivated as needed. The deactivation can be performed in sequence from the highest-level components to the lowest-level components to ensure that components that are needed by other components are not prematurely deactivated. A specific set of events transitions the portable computer out of the low power mode. | 11-20-2008 |
20100174796 | LOW POWER EMAIL FUNCTIONALITY FOR AN ELECTRONIC DEVICE - Low power email capabilities are provided for an electronic device, such as a hand-held portable computer having capability to operate an application during a low power mode. During the low power mode, portions of hardware, software, services, and/or other components of the portable computer that are not necessary for email-related operations, such as polling a server for new email, are suspended or otherwise deactivated. At least a portion of a new email is stored in a memory of a low power display module (LPDM) of the portable computer. The LPDM is provided with its own low-power processing unit, user interface, and other components to allow access to and manipulation of the stored email while other components of the portable computer remain deactivated. | 07-08-2010 |
Robert J. Kee, Arvada, CO US
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20120251912 | HIGH EFFICIENCY, REVERSIBLE FLOW BATTERY SYSTEM FOR ENERGY STORAGE - The present invention relates to a reversible solid oxide electrochemical cell that may operate in two modes: a discharge mode (power generation) and a charge mode (electrolytic fuel production). A thermal system that utilizes a SOFB and is inclusive of selection of operating conditions that may enable roundtrip efficiencies exceeding about 80% to be realized is disclosed. Based on leverage of existing solid oxide fuel cell technology, the system concept is applicable to energy storage applications on the kW to MW scale. | 10-04-2012 |
20120282534 | HIGH EFFICIENCY, REVERSIBLE FLOW BATTERY SYSTEM FOR ENERGY STORAGE - The present invention relates to a reversible solid oxide electrochemical cell that may operate in two modes: a discharge mode (power generation) and a charge mode (electrolytic fuel production). A thermal system that utilizes a SOFB and is inclusive of selection of operating conditions that may enable roundtrip efficiencies exceeding about 80% to be realized is disclosed. Based on leverage of existing solid oxide fuel cell technology, the system concept is applicable to energy storage applications on the kW to MW scale. | 11-08-2012 |
Robert L. Kee, Charlotte, NC US
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20090319424 | POSTAL MAIL DEPOSIT AGENCY - Apparatus and methods for electronically depositing a check in a bank account. In some embodiments, the apparatus and methods may involve a check identification module configured to analyze content of an electronically imaged postal mail item; and a customer control module configured to receive from a customer an instruction to deposit the check in the bank account. | 12-24-2009 |
Robert Leonard Kee, Charlotte, NC US
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20090164390 | SYSTEMS AND METHODS FOR ALTERING MAIL ROUTING, MAIL PROCESSING, AND/OR MODE OF DELIVERY - The present invention provides systems, methods, and computer program products for altering delivery of a piece by altering either the delivery address, mode of processing, and/or the mode of delivery. The invention provide an indicia associated with the piece of mail including instructions that are at least one of a different delivery address, mode of processing, or a mode of delivery than that originally designated for the piece of mail. During mail sorting and processing, the indicia associated with the piece of mail are analyzed. Either the delivery address, mode of processing, and/or mode of delivery currently associated with the piece of mail are altered to conform with the delivery address, mode of processing, and/or mode of delivery indicated by the indicia. In some embodiments, the indicia is altered by on a business parameter, such as a monetary value associated with the contents of the piece of mail. | 06-25-2009 |
Ronald W. Kee, Fort Collins, CO US
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20110099440 | SYSTEMS AND METHODS FOR MEASURING SOFT ERRORS AND SOFT ERROR RATES IN AN APPLICATION SPECIFIC INTEGRATED CIRCUIT - A test system includes a computer and an interface device for accessing a scan chain on an application specific integrated circuit (ASIC) under test. The computer includes a memory that contains application software that when executed by the computer quantifies soft errors and soft error rates (SER) in storage elements on the ASIC. The interface device receives commands and data from the computer, translates the commands and data from a first protocol to a second protocol and communicates the commands and data in the second protocol to the ASIC. A method for measuring SER in the ASIC includes baseline, comparison, and latch up accesses of data in a scan chain in the ASIC. Between accesses, the ASIC is exposed to a neutron flux that accelerates the occurrence of soft errors due to ionizing radiation upon the ASIC. | 04-28-2011 |
Ronald William Kee, Fort Collins, CO US
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20100297787 | SYSTEM AND METHOD FOR BACKSIDE CIRCUIT EDITING ON FULL THICKNESS SILICON DEVICE - A system for accessing circuitry on a flip chip circuit device with active circuitry and full-thickness bulk silicon includes a moveable surface for supporting and locating the circuit device in a plane, an infrared (IR) imaging device located at a defined perpendicular distance from a surface of the bulk silicon, the surface of the bulk silicon parallel to the plane and a milling chamber configured to direct an etchant and a focused ion beam to the surface of the bulk silicon, resulting in a gas-enhanced milling process that creates a milled cavity in the bulk silicon. The system produces an IR reflective material located at a base of the cavity, wherein the circuit device is located within a field of view of the IR imaging device such that the IR reflective material is brought into focus by moving the IR imaging device an adjustable distance perpendicular to the surface of the bulk silicon, and where the adjustable perpendicular distance is indicative of a depth of the cavity. | 11-25-2010 |
20120235057 | APPARATUS AND METHOD FOR FORMING A SOLID IMMERSION LENS USING A BINARY BITMAP MILLING PATTERN - A method for forming a solid immersion lens (SIL) includes generating a focused ion beam, and projecting the focused ion beam onto an optical medium at locations defined by a binary bitmap milling pattern, wherein the locations at which the focused ion beam impact a surface of the optical medium are randomized over successive raster scans of the surface of the optical medium to form at least a portion of a hemispherical structure in the optical medium. | 09-20-2012 |
Scott Kee, Mission Viejo, CA US
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20140347007 | Wireless Power Transfer (WPT) for a Mobile Communication Device - A wireless power transfer (WPT) station is disclosed for wirelessly transferring power to a WPT enabled device. To initiate charging of the WPT enabled device, the WPT enabled device is simply moved to be proximate to the WPT station. After an initialization and setup period, the WPT station transmits power transfer signals to the WPT enabled device. The WPT enabled device receives the transferred power transfer signals, typically through inductive coupling, and extracts a voltage and/or current therefrom for charging. The extracted voltage and/or current can then be rectified and/or regulated by the WPT enabled device to produce a charging voltage and/or charging current that can be stored in a power storage element, such as a battery or a capacitor to provide some examples, of the WPT enabled device. | 11-27-2014 |
Scott David Kee, Pasadena, CA US
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20090002071 | Distributed Circular Geometry Power Amplifier Architecture - The present invention discloses a distributed power amplifier topology and device that efficiently and economically enhances the power output of an RF signal to be amplified. The power amplifier comprises a plurality of push-pull amplifiers interconnected in a novel circular geometry that preferably function as a first winding of an active transformer having signal inputs of adjacent amplification devices driven with an input signal of equal magnitude and opposite phase. The topology also discloses the use of a secondary winding that matches the geometry of primary winding and variations thereof that serve to efficiently combine the power of the individual power amplifiers. The novel architecture enables the design of low-cost, fully-integrated, high-power amplifiers in the RF, microwave, and millimeter-wave frequencies. | 01-01-2009 |
Scott M. Kee, Bourbonnais, IL US
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20080274969 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 11-06-2008 |
20100310550 | ALPHA 1- ANTITRYPSIN COMPOSITIONS - A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as a Cohn fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as a dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitant. Separation of the solid adsorbent from the solution leaves a purified AAT solution that is directly suitable for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described. | 12-09-2010 |
20110092413 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 04-21-2011 |
20120165261 | Alpha-1-antitrypsin compositions - A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as a Cohn fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as a dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitant. Separation of the solid adsorbent from the solution leaves a purified AAT solution that is directly suitable for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described. | 06-28-2012 |
20140323405 | ALPHA-1-ANTITRYPSIN COMPOSITIONS - A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as a Cohn fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as a dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitant. Separation of the solid adsorbent from the solution leaves a purified AAT solution that is directly suitable for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described. | 10-30-2014 |
20150320846 | METHODS OF TREATMENT USING ALPHA-1-ANTITRYPSIN COMPOSITIONS - A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as Coh fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitante. Separation of the solid absorbent from the solution leaves a purified AAT solution that is directly suitable for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described. | 11-12-2015 |
Siak Chon Kee, Milpitas, CA US
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20150372679 | PVT Compensation Scheme for Output Buffers - In one integrated circuit embodiment, a programmable pull-down output buffer is calibrated by sequentially configuring the buffer at different drive-strength levels and adjusting a source current applied to the buffer until the voltage at an input node of the buffer reaches a reference voltage level. A programmable pull-up output buffer is then calibrated by sequentially configuring a pull-down output buffer based on the pull-down buffer calibration results and adjusting the drive-strength level of the pull-up buffer until the voltage at a common node between the two buffers reaches a reference voltage level. Average calibration results are generated by averaging multiple calibration results for each setting. Output buffers are thereby calibrated to compensate for PVT variations without using any external resistors and without requiring any I/O pins of the integrated circuit. | 12-24-2015 |
Stephen T. Kee, Santa Monica, CA US
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20150150442 | ENDOVASCULAR PROBE - An embodiment of an endovascular probe includes a probe body, an inflatable mechanism surrounding a portion of the probe body and configured to create a reversible occlusion within a vascular system, multiple channels extending through the probe body, and an imaging device positioned within one of the channels. Another embodiment of an endovascular probe includes a probe body with a first channel configured to accommodate an instrument, a second channel configured to accommodate an imaging device, and a third channel configured to accommodate an irrigation device, along with an inflatable device at an external periphery of the probe body. Another embodiment of an endovascular probe includes an image recording device, a bi-modal mechanism that selectively provides one of irrigation and suction, and a laser fiber. | 06-04-2015 |
20150366649 | Bidirectional Vascular Filter and Method of Use - The present invention relates to a device for filtering obstructive material within the vasculature of a subject. The device includes a generally ellipsoid shaped frame having a plurality of shape-memory arms with a collapsible, sieve-like structure positioned within the elliptical frame. The device may be used as an inferior vena cava (IVC) filter for the prevention of pulmonary embolism, or any other procedure requiring filtering of a vein. | 12-24-2015 |
Timothy A. Kee, Stevensville, MI US
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20090039033 | PORTABLE OZONATION APPARATUS FOR STORING AND PURIFYING LIQUID - A portable ozonation apparatus for storing and purifying liquids includes a container having an opening for receiving a liquid and a treatment cap. The treatment cap is preferably detachably mounted to the container at the opening. Preferably, the treatment cap includes a main body portion having provided therein an electricity generating device and an ozone generating device. With this arrangement, un-purified liquid, such as water, is introduced into the container. The container is then inverted to bring the un-purified liquid into contact with the ozone generating device. At this point, the electricity generating device is activated to deliver an electrical current to the ozone generating device. Once powered, the ozone generating device produces ozone which is introduced into the liquid container. The ozone gas transforms un-purified liquid into a purified liquid suitable for consumption. | 02-12-2009 |
20120125830 | PORTABLE OZONATION APPARATUS FOR STORING AND PURIFYING LIQUID - A portable ozonation apparatus for storing and purifying liquids includes a container having an opening for receiving a liquid and a treatment cap. The treatment cap is preferably detachably mounted to the container at the opening. Preferably, the treatment cap includes a main body portion having provided therein an electricity generating device and an ozone generating device. With this arrangement, un-purified liquid, such as water, is introduced into the container. The container is then inverted to bring the un-purified liquid into contact with the ozone generating device. At this point, the electricity generating device is activated to deliver an electrical current to the ozone generating device. Once powered, the ozone generating device produces ozone which is introduced into the liquid container. The ozone gas transforms un-purified liquid into a purified liquid suitable for consumption. | 05-24-2012 |
20140151285 | VERTICALLY STACKED OR DIVIDED FLUID FILTER SYSTEM FOR INLET, OUTLET OR BOTH INLET AND OUTLET FILTERING - A liquid (water) pitcher that includes a pitcher having a liquid receiving aperture configured to allow a liquid (water) to be delivered into an interior liquid storage volume defined by at least one upwardly extending wall extending upward from a base and a liquid (water) filter positioned within the pitcher that includes a filter housing and at least one gravity-driven fluid treatment medium within the filter housing where the filter housing has a plurality of fluid intake apertures and at least one treated fluid outlet configured to deliver treated fluid into an internal volume of a vessel wherein the at least one fluid filtering medium treats the liquid at a rate of at least about one liter per minute while removing at least chlorine odor and chlorine taste components from the liquid (water). | 06-05-2014 |
20140151304 | GRAVITY FLUID/WATER FILTER ENGINE SYSTEM - A gravity-driven fluid filtering system that includes a universal fluid (typically water) filter and a plurality of differently sized fluid dispensing adapters. The universal fluid filter includes: at least one gravity-driven fluid filter media; a housing having an interior and at least one fluid inlet aperture configured to allow a fluid to be treated to enter the interior of the housing by a force of gravity and into contact with the at least one gravity-driven water filter media spaced within the interior of the housing; and at least one treated fluid outlet aperture configured to deliver treated fluid to at least one of a plurality vessels each having a differently sized fluid receiving aperture. The plurality of differently sized fluid dispensing adapters each having a sloped and contoured fluid receiving portion, which is different for each adapter. | 06-05-2014 |
20150027147 | AIR CONDITIONING SYSTEMS WITH MULTIPLE TEMPERATURE ZONES FROM INDEPENDENT DUCTING SYSTEMS AND A SINGLE OUTDOOR UNIT - A high-efficiency air conditioning system for conditioning a plurality of zones within an interior of a building that includes: at least two independent ductwork systems within a building wherein each independent ductwork system directs heating and cooling to one zone within the building; a single outdoor unit a refrigerant flow pathway having a common refrigerant flow path portion, a first divergent flow path, and a second divergent flow path; at least one throttling device and at least a first indoor air handling unit providing cooling to a first independent ductwork system and a second indoor air handling unit providing cooling to a second indoor ductwork system. The compressor is incapable of simultaneously supplying both the first evaporator and the second evaporator at their full cooling capacity. | 01-29-2015 |
20150027151 | AIR CONDITIONING SYSTEMS FOR AT LEAST TWO ROOMS USING A SINGLE OUTDOOR UNIT - A high-efficiency air conditioning system for conditioning a plurality of rooms within an interior of a building, the air conditioning system including: two separate rooms within a building, a single outdoor unit a refrigerant flow pathway that includes a plurality of refrigerant conduits having a common refrigerant flow path portion and at least two divergent flow path portions, a first divergent flow path where the first evaporator and second evaporator are in parallel with one another; at least one throttling device and at least a first indoor air handling unit positioned within and providing cooling to the first room and a second indoor air handling unit positioned within and providing cooling to a second room. The compressor is incapable of simultaneously supplying both the first evaporator and the second evaporator at their full cooling capacity. | 01-29-2015 |
Trisha Vanbrederode Kee, Ponte Vedra, FL US
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20130337428 | LEARNING CONCEPT ORGANIZER - The present invention is a learning organizer for assisting a learner. The learning organizer comprises a sheet having a front portion and a rear portion, the sheet folded substantially along a central line to form a first half and a second half, a plurality of flaps located on the first half, a plurality of holes provided along and proximate to the central line and punched through the first half and the second half, a plurality of lines on the rear portion and a plurality of fill-in-blanks pre-printed on the second half to write details of the learner. Each of the plurality of flaps includes a plurality of perforations and a plurality of scorings. The plurality of lines is provided for neat writing. The learning organizer allows the learner to write down learning information into each of the plurality of flaps so as to present, organize, learn and memorize learning concepts. | 12-19-2013 |
William P. Kee, San Francisco, CA US
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20140214535 | CONTENT SEQUENCING - This specification describes technologies relating to selection and display of content items based in part on sequencing information. In general, one aspect of the subject matter described in this specification can be embodied in methods that include receiving a request for content and a user identifier. The methods may further include identifying a sequence of content items in a browsing history corresponding to the user identifier, where the content items in the sequence are members of a set of content items. The methods may further include retrieving an estimate of a conditional probability of conversion for a first content item from the set, where the first content item is presented after the identified sequence. The methods may further include determining a bid for an impression in the requested content based in part on the estimate of the conditional probability of conversion and transmitting the bid. | 07-31-2014 |
William Patrick Kee, San Francisco, CA US
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20150161652 | METHODS AND SYSTEMS FOR DISPLAYING ATTRIBUTION CREDIT DATA BASED ON PARAMETERS - Methods and systems for providing for display attribution data associated with one or more events are disclosed. Processor identifies channels from paths including events corresponding to position data identifying a position along the path at which the event was performed. Processor determines attribution credits assigned to each event included in the paths corresponding to the channel. Processor determines a number of attribution credits assigned to the channel. Processor identifies, from the paths, a plurality of event-position pairs. Each event-position pair corresponds to events that correspond to a respective channel and are performed at a respective position of the plurality of paths corresponding to the event-position pair. Processor determines, for each identified event-position pair, a weighting based on an aggregate of the attribution credits assigned to the events to which the event-position pair corresponds. Processor provides, for display, a visual object including an indicator to display the determined weightings. | 06-11-2015 |
20150213511 | BID ADJUSTMENT BASED ON PRESENTATION OF RELATED CONTENT THROUGH OTHER COMMUNICATION MEDIUM - Systems, methods, and computer-readable storage media that may be used to adjust bid settings based on content presented through other communication media are provided. One method includes determining a time at which a first content item of a content provider is likely to have been presented to a plurality of users through a first communication medium. The method further includes adjusting a current bid setting for at least one bid for one or more auctions to be displayed through a content interface on one or more user devices. The bid is adjusted for a time period after the determined time, and is associated with at least one second content item that is related to a subject matter of the first content item. The method further includes applying the adjusted bid setting to the at least one bid for content auctions that are conducted during the time period. | 07-30-2015 |
William Patrick Kee, Mountain View, CA US
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20150161655 | Methods and Systems for Selecting Content for Display Based on Conversion Probabilities of Paths - Systems and methods for selecting content for display at a device includes, identifying by a processor, a visitor identifier associated with a device on which to display content. The processor can identify a path associated with the visitor identifier. The path corresponding to a sequence of one or more events through which the visitor identifier has visited the website. The processor can identify a conversion probability of the identified path. The conversion probability of the identified path indicates a likelihood that the visitor identifier will convert at the website. The conversion probability of the identified path is a ratio of a number of conversions at the website to a number of visits to the website over a given time period. The processor can select content for display. The content selected based on the identified conversion probability of the identified path. | 06-11-2015 |
20150161657 | Methods and Systems for Measuring Conversion Probabilities of Paths for an Attribution Model - Systems and methods for measuring conversion probabilities of a path types for an attribution model includes, identifying by a processor, paths taken by visitors to visit a website. The paths correspond to a sequence of events that cause a visitor to visit the website. The processor can identify as paths, for each path, subpaths corresponding to each visit to the website. The processor computes a total path count for each path type. The processor identifies, for each path type, a conversion path count indicating a number of paths taken by visitors that resulted in a conversion at the website. The processor calculates, for each path type, a probability of conversion and then provides the calculated probability of conversion for a given path type for an attribution model used in assigning attribution credit to events of a path. | 06-11-2015 |
20150161658 | METHODS AND SYSTEMS FOR CREATING A DATA-DRIVEN ATTRIBUTION MODEL FOR ASSIGNING ATTRIBUTION CREDIT TO A PLURALITY OF EVENTS - Systems and methods for creating a data-driven attribution model are described. A processor identifies visits to a website. The processor identifies a path for each visitor identifier associated with the visits. The processor determines, for each path type associated with the identified paths, a path-type conversion probability based on a number of visits corresponding to the path type that resulted in a conversion. The processor calculates, for each of a plurality of the path types, a counterfactual gain for each event based on a conversion probability of the given path type and a conversion probability of a path type that does not include the event for which the counterfactual gain is calculated. The processor determines, for each event, an attribution credit based on the calculated counterfactual gain of the event. The processor then stores the attribution credits of each of the events. | 06-11-2015 |
20150237395 | SYSTEMS AND METHODS FOR ENHANCING AUDIENCE MEASUREMENT DATA - The present disclosure provides systems and methods for enhancing audience measurement data. Offline and online audience measurement data may be compared and correlated to improve the quality of each data and source set. Positive correlations between the offline and online data sets related to a particular event may indicate demographic traits that are likely true, such that outliers may be removed from the set or considered at a reduced weight. Negative correlations may indicate that demographic information within a source set, such as the online measurement data, may be false or suspect. | 08-20-2015 |
Yun Kee, San Marino, CA US
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20080284430 | MAGNETIC RESONANCE STAGE MICROSCOPE - A magnetic resonance (MR) microscope and a dual-mode optic and MR microscope system are disclosed, The MR microscope is provided with a horizontal stage above which a sample to be analyzed is located, a radiofrequency coil assembly located above the horizontal stage and below the sample, a magnetic field gradient module located under the horizontal stage, and a heat exchange unit thermally coupled to the magnetic field gradient module and located under the magnetic field gradient module. The dual-mode optic and MR microscope system is provided with an MR microscope and an optical microscope, the optical microscope comprising a mirror located above the sample | 11-20-2008 |