Kaufmann, DE
Alexander Kaufmann, Dinslaken DE
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20110184212 | PROCESS FOR PREPARING NEOPENTYL GLYCOL BY CRACKING HIGH BOILERS OCCURING IN THE PRODUCTION PROCESS - The present invention relates to a process for obtaining neopentyl glycol by hydrogenating cracking of high-boilers occurring in the production process in the presence of copper-chromite catalysts. The hydrogenating cracking proceeds in the absence of solvent at a temperature of 140 to 220° C. and at pressures of 7 to 28 MPa. | 07-28-2011 |
20120035393 | METHOD FOR PRODUCING ALIPHATIC CARBOXYLIC ACIDS FROM ALDEHYDES BY MICROREACTION TECHNOLOGY - A process for preparing aliphatic carboxylic acids having 3 to 10 carbon atoms by oxidizing the corresponding aldehydes with oxygen or oxygen-containing gases, characterized in that (i) the oxidation is performed in a microreactor at elevated pressure and with an oxygen excess based on the stoichiometrically required amount of oxygen, and (ii) in that the reaction mixture removed from the microreactor is passed through at least one postreactor without further addition of oxygen, and (iii) wherein the oxidation reaction in the microreactor is performed under such conditions that aldehyde and corresponding peracid formed are present in the reaction mixture removed in a molar ratio within a range of | 02-09-2012 |
Andre Kaufmann, Bochum DE
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20090161771 | Fft carrier frequency offset estimation for ofdm signal - There is being disclosed an OFDM signal receiver for detecting carrier frequency offset. When FFT transform of the signal is processed in the receiver, an estimator applies the spectrum shape of the FFT transform for estimating the carrier frequency offset. | 06-25-2009 |
20090210147 | Method, Apparatus and Computer Program Product for Map Generation Using Perpendicular Projection to Merge Data - An apparatus for enabling generation of a map using perpendicular projection to merge data may include a processor. The processor may be configured to receive an indication of a first trace defining a first position history and a second trace defining a second position history, perform a perpendicular projection calculation with respect to portions of the first and second traces, and merge the first trace and the second trace on the basis of the perpendicular projection calculation. | 08-20-2009 |
Andre Kaufmann, Baienfurt DE
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20100170245 | TURBOCHARGER CONFIGURATION AND TURBOCHARGEABLE INTERNAL COMBUSTION ENGINE - A turbocharger configuration, particularly in or for a motor vehicle, includes at least one turbocharger stage, which has a turbine and a compressor that are mechanically decoupled from each other. A turbochargeable internal combustion engine having such a turbocharger configuration, is also provided. | 07-08-2010 |
20100178163 | Radial Compressor with a Diffuser for Use in a Turbocharger - A radial compressor, in particular for a turbo-charger, has a spiral housing and a diffuser. The diffuser is constructed such that a low-pressure region in the area of the transition between the spiral housing and the tongue is at least reduced. | 07-15-2010 |
20100296924 | Guide Vane for a Variable Turbine Geometry - A guide vane, particularly for a turbocharger, has a line of curvature with at least one or more sectors having a discontinuous course. | 11-25-2010 |
20110189011 | TURBOCHARGER HAVING AN INSERTION PLATE - A turbocharger has a rotor housing. Said rotor housing has an insertion element. Said insertion element is configured such that the same forms an over-hanging spiral together with said rotor housing. | 08-04-2011 |
Andre Kaufmann, Tegernheim DE
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20100135773 | TURBOCHARGER HAVING A DEVICE FOR DETECTING A MALFUNCTION OF THE TURBOCHARGER AND A METHOD FOR DETECTING SUCH A MALFUNCTION - The turbocharger having a device for detecting a malfunction of the turbocharger, particularly a malfunction of at least one bearing of the turbocharger has the following features: The device for detecting a malfunction of the turbocharger has a memory device, in which the target operating states of an intact turbocharger are stored. The device for detecting a malfunction of the turbocharger further has a comparing device, in which the determined actual operating state of the turbocharger is compared to a corresponding target operating state of an intact turbocharger. The turbocharger further has a measuring device for determining an actual operating state of the turbocharger, wherein the device for detecting a malfunction of the turbocharger emits an error message if the comparing device detects that the actual operating stage deviates from the target operating state by a predefined measure. | 06-03-2010 |
20100254816 | Exhaust Gas Turbocharger - A turbocharger for or in a motor vehicle has a rotor with an intermediate blade disposed between two primary blades. The intermediate blade, at least in some regions, has an angular progression that differs from the primary blades. | 10-07-2010 |
Andreas Kaufmann, Kirchzarten DE
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20110165692 | METHOD FOR CAPTURING MEASUREMENT VALUES AND DISPLAYING MEASUREMENT VALUES - A method for determining an NO | 07-07-2011 |
20140000343 | HANDHELD SAMPLING-REMOVAL HEAD, ANALYSIS ARRANGEMENT AND METHOD FOR CHARACTERIZING AN AEROSOL | 01-02-2014 |
Andreas Kaufmann, Backnang DE
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20110154800 | CHAIN LINK FOR AN ENERGY GUIDING CHAIN - The invention relates to a chain link ( | 06-30-2011 |
Angela Kaufmann, Essen DE
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20120149832 | NON-AQUEOUS DISPERSION OF POLYMER PARTICLES IN REACTIVE DILUENT - The invention relates to a non-aqueous dispersion of organic polymer particles in a reactive diluent. Said non-aqueous dispersion can be obtained in that at least one monomer is polymerized in the reactive diluent, forming the organic polymer particles, wherein the reactive diluent does not participate in said polymerization due to the orthogonal reactivity thereof relative to the monomers, but comprises a functionality allowing later targeted polymerization. Depending on the organic polymer particles or reactive diluents used, the non-aqueous dispersion can be used in multifaceted applications having a wide range of application profiles. In order to produce said non-aqueous dispersion, polymerization of at least one monomer in a stirred tank reactor in the presence of a reactive diluent is particularly suitable, wherein the conversion is performed at a stirring speed of at least 2 m/s, wherein the ratio of the stirrer diameter to the vessel diameter is set to 0.3-0.80 and the distance from the stirrer to the vessel floor is set to 0.25 to 0.5 times the stirrer diameter. The invention provides multifaceted advantageous applications, particularly as an impact strength modifier, particularly in films, and as an adhesive, as casting resin, or as paint. A particularly advantageous application is producing a molded part or a semi-finished polymer product. | 06-14-2012 |
Artur Kaufmann, Landau DE
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20120136869 | System and Method of Processing Information Stored in Databases - In one embodiment the present invention includes a computer implemented method of processing information stored in a data structure. The method includes continuously generating individual records and storing the individual records in a database as a plurality of records. The method further includes selecting, according to a time period, a set of the plurality of records that qualify according to the time period. The method further includes moving the set to a table in the database, wherein the table excludes the plurality of records that are not in the set. In this manner, the records may be stored in a number of parallel tables, and this process may be managed at the application level instead of at the database level. Using parallel tables instead of a single large table may offer performance improvements, for example regarding deleting (or archiving) data. | 05-31-2012 |
20130046940 | OPTIMIZATION OF MEMORY BY TAILORED GENERATION OF RUNTIME STRUCTURES - Data structures used to store data in an enterprise resource planning (ERP) system may be configured and custom-generated in a configuration mode of the ERP system where a subset of selectable data fields may be selected to avoid allocating space and resources to unused data fields. The data structures may then be generated in the configuration mode to eliminate the unused data fields at runtime. This in turn saves space and resources that would otherwise be allocated but not used. In ERP systems substantial space and computing resources may be saved by only allocating space and resources to only those resources that a specific customer intends to use. | 02-21-2013 |
20130061026 | CONFIGURABLE MASS DATA PORTIONING FOR PARALLEL PROCESSING - A configurable mass data portioning for parallel processing is described herein. One or more operation attributes are selected to participate in parallelization criteria. The values of the selected operation attributes for a number of operations are submitted to a specified algorithm using to provide parallelization values corresponding to the operations. The parallelization values are applied to group the operations in comparable portions for parallel execution without conflicts. | 03-07-2013 |
20140089149 | MASS REVERSAL OF DOCUMENTS BASED ON REVERSAL TASKS AND REVERSAL TRIGGERS - In an example embodiment, a mass reversal of documents in a convergent invoicing system may be accomplished by first receiving a first set of one or more reversal triggers, wherein each of the one or more task triggers corresponds to a document in the convergent invoicing system. Then a reversal task is received, wherein the reversal task corresponds to the first set of one or more reversal triggers. A second set of reversal triggers may then be automatically corresponded to reversal task, based upon documents corresponding to the one or more task triggers in the first set of ne or more reversal triggers. Once an indication that the reversal task has been released in received, for each reversal trigger corresponding to the reversal task, the reversal trigger is processed, causing a corresponding document to be reversed. | 03-27-2014 |
Bernd Kaufmann, Hassfurt DE
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20080258464 | Fitting for a tube - A fitting tube including a fitting body ( | 10-23-2008 |
20100259039 | PRESS FITTING FOR A PIPE, IN PARTICULAR PLASTIC PIPE OR PLASTIC AND METAL COMPOSITE PIPE - The press fitting for a pipe, in particular plastic pipe or plastic-metal composite pipe, is provided with a fitting body ( | 10-14-2010 |
20110101673 | PRESS-ON FITTING FOR A PIPE,IN PARTICULAR PLASTIC PIPE, OR PLASTIC-METAL COMPOSITE PIPE - The invention relates to a fitting for a pipe, particularly a plastic pipe or plastic-metal composite pipe, having a base body ( | 05-05-2011 |
20110219594 | TOOL DEVICE FOR CONNECTION OF A PLASTIC PIPE - A tool device for the connection of a plastic pipe, particularly a plastic/metal composite pipe, to a fitting having a compression or sliding sleeve, has a housing ( | 09-15-2011 |
Boris Kaufmann, Aichtal DE
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20090073628 | SAFETY SWITCHING APPARATUS - A safety switching apparatus for the failsafe disconnection of an electrical load has a first and a second terminal for supplying a first and a second signal from a signaling device, such as an emergency-off button. The safety switching apparatus also has a first and a second switching element which together produce a redundant output switching signal for disconnecting the load. The first switching element has a first control circuit to which the first signal is supplied. The second switching element has a second control circuit to which the second signal is supplied. The safety switching apparatus further has circuitry providing a first current path, an alternative second current path and at least one further switching element. The at least one further switching element is designed to select either the first or the second current path, depending on a polarity of the second signal, in order to route the second signal to the second control circuit. | 03-19-2009 |
20110133574 | SAFETY SWITCHING APPARATUS - A safety switching apparatus for the failsafe disconnection of an electrical load has a first and a second terminal for supplying a first and a second signal from a signaling device, such as an emergency-off button. The safety switching apparatus also has a first and a second switching element which together produce a redundant output switching signal for disconnecting the load. The first switching element has a first control circuit to which the first signal is supplied. The second switching element has a second control circuit to which the second signal is supplied. The safety switching apparatus further has circuitry providing a first current path, an alternative second current path and at least one further switching element. The at least one further switching element is designed to select either the first or the second current path, depending on a polarity of the second signal, in order to route the second signal to the second control circuit. | 06-09-2011 |
Carsten Kaufmann, Mulheim A.d. Ruhr DE
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20110239650 | POWER PLANT COMPRISING A TURBINE UNIT AND A GENERATOR - A power plant including a turbine unit having a turbine, a generator connected to the turbine for power transmission, and a cooling device for cooling the generator is provided. The cooling device is provided to release waste heat from the generator to a device of the power plant. Waste heat may be used in the power plant process, thus attaining increased efficiency. | 10-06-2011 |
20110280712 | Passage wall section for an annular flow passage of an axial turbomachine with radial gap adjustment - A passage wall section of an annular flow passage of an axial turbomachine is provided. A guide ring has a first toothing arrangement which is in contact with a second toothing arrangement arranged on a sidewall of a circumferential groove which accommodates the guide ring, wherein for axial displacement of the displaceable guide ring, the guide ring is rotatable in a circumferential direction. | 11-17-2011 |
Christian Kaufmann, Burgstaedt DE
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20100024562 | MEMS VACUUM SENSOR BASED ON THE FRICTION PRINCIPLE - The invention relates to a sensor element for pressure measurement, having a substrate ( | 02-04-2010 |
20110303515 | ELECTROSTATICALLY ACTUATED MICRO-MECHANICAL SWITCHING DEVICE - An electrostatically actuated micro-mechanical switching device with movable elements formed in the bulk of a substrate for closing and releasing at least one Ohmic contact by a horizontal movement of the movable elements in a plane of the substrate. The switching device has a drive with comb-shaped electrodes including fixed driving electrodes and movable electrodes. A movable push rod is mechanically connected with the movable electrodes, extends through the electrodes, has a movable contact element at one side, and at least one restoring spring. A signal line has two parts interrupted by a gap. The micro-mechanical switching device is in shunt-configuration with low loss, high isolation in a wide frequency range, low switching time at low actuation voltage and sufficient reliability. The line impedance of the signal line and its variation is as small as possible. The switching device is in shunt-configuration for closing and releasing the Ohmic contact between a ground line and the signal line. The contact element has a movable contact beam extending at least partially opposite to the signal line and being electrically and mechanically connected to both parts of the signal line, respectively. The ground line is formed with a contact bar that leads through the gap of the signal line for forming the Ohmic contact between the contact beam and the ground line. A contact metallization is provided at least on top and on the side walls of the contact beam, of the signal line and of the ground line. | 12-15-2011 |
Christian Kaufmann, Berlin DE
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20120006403 | Solar Cells With A Barrier Layer Based On Polysilazane - The invention relates to a thin-film solar cell ( | 01-12-2012 |
20120017985 | Solar Cells With An Encapsulating Layer Based On Polysilazane - The invention relates to a thin-film solar cell ( | 01-26-2012 |
Christoph Kaufmann, Haag DE
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20110015443 | PROCESS FOR CONTINUOUSLY PREPARING METHYL MERCAPTAN FROM CARBON COMPOUNDS, SULFUR AND HYDROGEN - The invention relates to a process for continuously preparing methyl mercaptan by reacting a mixture comprising carbon compounds with sulfur and hydrogen, wherein the carbon disulfide and hydrogen sulfide compounds which form are subsequently converted to methyl mercaptan. | 01-20-2011 |
Dominic Kaufmann, Roding DE
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20110184215 | BIOMASS PYROLYSIS IN REFINERY FEEDSTOCK - This invention relates to biomass pyrolysis through the use of a hot liquid refinery feedstock as a heat transfer medium, preferably a vacuum gas oil feedstock. | 07-28-2011 |
Franz Kaufmann, Freiburg DE
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20100330384 | METHOD OF TREATING CELLULOSIC MATERIALS WITH HYDROPHOBINS - By treatment with hydrophobins, cellulosic materials such as paper, cardboard, cotton or, especially, wood-based materials, such as solid wood, glued wood products or particle board, can be effectively protected against absorption of and attack by water and/or moisture. | 12-30-2010 |
20110159050 | AMPHIPHILIC PROTEINS AS MORPHOLOGY MODIFIERS - Disclosed is a process for modifying the morphology and/or polymorphism of an organic substance, which process comprises treating the solid substance, or a solution or dispersion thereof, with one or more amphiphilic proteins. | 06-30-2011 |
20120058199 | COMPOSITIONS, USE AND METHOD FOR THE USE OF SURFACE ACTIVE PROTEINS IN TOPICAL DRUG DELIVERY ACROSS KERATIN - The present invention provides the use of surface active proteins, especially class I and class II hydrophobins, in topically applied pharmaceutical formulations. The invention is particularly directed to topically applied pharmaceutical products for enhancing the penetration to achieve a transungual delivery of a prophylactically and/or therapeutically effective amount of an active ingredient (drug) to a patient (including animals and humans) into and/or through a nail, of the animal or human body, in order to treat one or more of a variety of diseases or disorders. Related embodiments of the invention are also disclosed. | 03-08-2012 |
20120164162 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES - A method for the manufacture of products by biotechnological methods in bacterial cell culture is disclosed as well as products obtained, the use of certain additives to the media used in the manufacture of said products in bacterial cell culture media, and the use of said additives in reducing the detrimental effects of radicals in the manufacture of the products, as well as aspects related to these invention embodiments. The manufacturing process or method comprises adding one or more radical scavenging and/or antioxidative additive preferably selected from the group consisting of sterically hindered nitroxyls, sterically hindered hydroxylamines, sterically hindered hydroxylamine salt compounds, sterically hindered amino compounds and sterically hindered N-hydrocarbyloxyamines, benzofuranone compounds, as obligatory component(s) to the medium used during biosynthesis. | 06-28-2012 |
20120309036 | Test Arrangement - The invention relates to an arrangement, comprising a solid carrier and a matrix arranged on the solid carrier, said matrix comprising at least one enzymatically convertible or modifiable molecule and comprising at least one enzyme that can be released by the conversion or modification of the molecule, said enzyme being capable of converting at least one color-changing substrate located in the matrix and/or on the solid carrier. | 12-06-2012 |
Franz Kaufmann, Frieburg DE
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20110268792 | SURFACE ACTIVE PROTEINS AS EXCIPIENTS IN SOLID PHARMACEUTICAL FORMULATIONS - The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pharmaceutical forms with a hydrophobin-containing solution to modify the pharmaceutical properties of the galenic form. In a preferred embodiment of the invention hydrophobins are used to improve the properties of a pharmaceutical composition, e.g. to act as a surfactant or to increase resistance to disintegration of the galenic forms to achieve a retarded drug release. The galenic form to be modified by the use of surface active proteins as excipients can be capsules, tablets, pills, microparticles, vesicles, and suppositories, although further galenic forms are envisioned. The surface active proteins used for the purpose of present invention can either be isolated from their respective natural source or prepared by recombinant techniques and expression in a suitable host. | 11-03-2011 |
Gerhard Kaufmann, Herrenberg DE
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20110017824 | TELESCOPIC SIGHT - Telescopic sight, in particular for a handgun, comprising an optical lens system which is integrated in an essentially elongated outer tube which preferably has a circular cross section and can be fitted to the handgun or the like, which optical lens system is terminated by an eyepiece at an end facing the shooter's eye when the gun is being used, and by an objective at its opposite end, and has, between the eyepiece and the objective, at least one image plane lying in the optical beam path of light beams passing through the eyepiece and the objective, wherein a graticule structure lying in the beam path is arranged in the or at least one of the image planes, characterized in that the graticule structure comprises a virtual image of a graticule smiled outside the beam path, said virtual image being projected into the (respective) image plane. | 01-27-2011 |
Harald Kaufmann, Hattingen DE
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20110064912 | Screen Print Reflection Transfer and Process for the Manufacture Thereof - The invention relates to a method for manufacturing a screen print reflection transfer product and to reflection transfer systems produced by this method. According to said method, the reflecting color is provided with a multitude of reflecting particles, said reflecting particles protruding from the surface of the top color coat. | 03-17-2011 |
20120298025 | Process for the Production of a Textile Product - A process for the production of a textile product includes placing a flat motif template on a textile substrate, sewing the motif template onto the textile substrate in such a way that a perforation defining a desired motif in the motif template is produced, removing the part of the motif template, that is outside the motif defined by the perforation, and permanently fixing the remaining part, having the motif, of the motif template to the textile substrate. | 11-29-2012 |
20130213248 | Screen Print Reflection Transfer and Process for the Manufacture Thereof - The invention relates to a method for manufacturing a screen print reflection transfer product and to reflection transfer systems produced by this method. According to said method, the reflecting color is provided with a multitude of reflecting particles, said reflecting particles protruding from the surface of the top color coat. | 08-22-2013 |
20140093707 | Method of Producing a Motif Having Reflecting Properties and Transferring said Motif onto a Substrate, and a Reflection Transfer Film - A method of producing a motif having reflecting properties and transferring said motif onto a substrate includes providing an adhesive-repellent base medium; applying a transfer adhesive to the base medium over the full surface area; applying a reflection colorant which contains a multiplicity of reflection particles; cutting a motif into the layer structure produced, wherein a projecting region remains; removing said projecting region; and applying the layer structure having the motif, after removal of the base medium, to a substrate. | 04-03-2014 |
20140099483 | Method of Producing a Reflection Transfer for Transferring a Motif onto a Substrate - A method of producing a reflection transfer for transferring a motif onto a substrate includes providing an adhesive-repellent base medium, applying a transfer adhesive to the base medium, creating a colored print image by offset printing or digital printing, and applying at least one reflection layer which contains a multiplicity of reflection particles. | 04-10-2014 |
20140120290 | Screen Print Reflection Transfer and Process for the Manufacture Thereof - The invention relates to a method for manufacturing a screen print reflection transfer product and to reflection transfer systems produced by this method. According to said method, the reflecting color is provided with a multitude of reflecting particles, said reflecting particles protruding from the surface of the top color coat. | 05-01-2014 |
Heinz Kaufmann, Bad Konig DE
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20080315941 | Flat Substrate Having an Electrically Conductive Structure - The description is of a flat substrate with an electrically conductive structure integrated inside the flat substrate or applied to a surface of the flat substrate and/or with a technically improved surface. | 12-25-2008 |
Hitto Kaufmann, Ingelheim DE
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20090247609 | SM-PROTEIN BASED SECRETION ENGINEERING - The present invention concerns the field of cell culture technology. It describes a novel method for enhancing the secretory transport of proteins in eukaryotic cells by heterologous expression of Munc18c, Sly1 or other members of the SM protein family. This method is particularly useful for the generation of optimized host cell systems with enhanced production capacity for the expression and manufacture of recombinant protein products. | 10-01-2009 |
Hitto Kaufmann, Ulm DE
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20080268470 | METHODS OF SELECTING CELL CLONES - The invention describes novel methods for selecting cell clones which produce high amounts of protein of interest. In one method the amount of protein is measured before the cells are passaged for the first time. In another method a high throughput automated platform is used under sterile environment conditions with class A particle load of less than 100 particles per m3. | 10-30-2008 |
20080300207 | PROTEIN PRODUCTION - The invention concerns the field of protein production and cell culture technology. CERT is identified as a novel in vivo PKD substrate. Phosphorylation on serine 132 by PKD decreases the affinity of CERT towards its lipid target phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity, identifying PKD as a regulator of lipid homeostasis. The present invention shows that CERT in turn is critical for PKD activation and PKD dependent protein cargo transport to the plasma membrane. The interdependence of PKD and CERT is thus a key to the maintenance of Golgi membrane integrity and secretory transport. | 12-04-2008 |
20090018099 | PROTEIN PRODUCTION - The invention concerns the field of protein production and cell culture technology. CERT is identified as a novel in vivo PKD substrate. Phosphorylation on serine 132 by PKD decreases the affinity of CERT towards its lipid target phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity, identifying PKD as a regulator of lipid homeostasis. The present invention shows that CERT in turn is critical for PKD activation and PKD dependent protein cargo transport to the plasma membrane. The interdependence of PKD and CERT is thus a key to the maintenance of Golgi membrane integrity and secretory transport. | 01-15-2009 |
20100021911 | PRODUCTION HOST CELL LINES - The invention concerns the field of cell culture technology. The invention describes production host cell lines comprising vector constructs comprising a DHFR expression cassette. Those cell lines have improved growth characteristics in comparison to DHFR-deficient or DHFR-reduced cell lines such as CHO DG44 and CHO DUKX-B11. The invention especially concerns two cell lines, a representative of each cell line is deposited with the DSMZ under the number DSM ACC2909 (CHOpper® Discovery) and DSM ACC2910 (CHOpper® Standard). The invention further concerns a method of producing proteins using the cells generated by the described method. | 01-28-2010 |
20100086947 | USE OF FLOW-CYTROMETRIC ANALYSIS TO OPTIMIZE CELL BANKING STRATEGIES FOR CHO CELLS - Production of biopharmaceuticals from CHO cells requires generation of master-, working- and post-production cell banks of high quality, partly under GMP conditions. An optimal cryopreservation strategy is needed for each new production cell line, particularly with regard to the desire to establish production processes that are completely devoid of serum or even any animal components and to ensure robust thaw performance for reliable production. Here we describe a novel strategy employing flow cytometric (FC) analysis of Annexin V-stained cells for high-throughput characterization of CHO cell banks. Our data show that this method enables evaluation of a cryopreservation procedure just 6 h after thaw. | 04-08-2010 |
20100086967 | CELL GROWTH - The invention concerns the field of cell culture technology. It concerns a method of improving cell growth, especially the growth of biopharmaceutical producer host cells. The invention further concerns a method of producing proteins using the cells generated by the described method. | 04-08-2010 |
20110124108 | EPIGENETIC ENGINEERING - The invention concerns the field of cell culture technology. It concerns production host cell lines with increased expression of ribosomal RNA (rRNA) achieved through reducing expression of NoCR proteins, especially of TIP-5. Those cell lines have improved secretion and growth characteristics in comparison to control cell lines. | 05-26-2011 |
20110230642 | METHOD FOR INCREASING RECLONING EFFICIENCY - The present invention relates to the field of cell culture technology and relates to methods of replicating/cloning cells, preferably cell lines which are important for the production of biopharmaceuticals. The invention also relates to methods of preparing proteins using cells that have been obtained and replicated by single cell deposition and compositions which make it possible to replicate individual cells. | 09-22-2011 |
20110262967 | USE OF HSA-PRODUCING CELLS - The present invention refers to the area of cell culture technology and relates to methods for multiplying/cloning cells, preferably cell lines, which are important to the production of biopharmaceuticals. The invention further relates to methods for manufacturing proteins and to the use of cells extracted and multiplied through single cell sorting and to media compositions that enable a multiplication of single cells. Through the use of albumin-producing, preferably HSA-producing, cells as feeder cells for the conditioning of medium or as host cells, the recloning efficiency and thereby the quantity of clones obtained can be significantly increased. A combination of these approaches is also possible. Through the use of albumin-producing, preferably HSA-producing, cells, an increase in the recloning efficiency can be achieved in serum-free and/or insulin-free medium as well, and in different cell types. | 10-27-2011 |
20110281301 | THE SECRETORY CAPACITY IN HOST CELLS - The invention concerns the field of protein production and cell culture technology. It describes a method of producing a heterologous protein of interest in a cell comprising a. Increasing the expression or activity of a secretion enhancing gene, and b. Increasing the expression or activity of an anti-apoptotic gene, and c. Effecting the expression of said protein of interest, whereby the secretion enhancing gene is a gene encoding a protein whose expression or activity is induced during one of the following cellular processes: plasma-cell differentiation, unfolded protein response (UPR), endoplasmic reticulum overload response (EOR). | 11-17-2011 |
20120100553 | CHO/CERT CELL LINES - The invention concerns the field of cell culture technology. The invention describes production host cell lines comprising vector constructs comprising a CERT S132 A expression cassette. Those cell lines have improved growth characteristics and high CERT S132A expression levels. The invention especially concerns two cell lines deposited with the DSMZ under the number DSM ACC2989 (CHO/CERT 2.20) and DSM AC-C2990 (CHO/CERT 2.41). The invention further concerns a method of generating such preferred production host cells and a method of producing proteins using the two cell lines deposited with the DSMZ under the number DSM ACC2989 (CHO/CERT 2.20) and DSM ACC2990 (CHO/CERT 2.41). | 04-26-2012 |
20120190065 | COMBINATORIAL ENGINEERING - The invention concerns the field of cell culture technology. It concerns production host cell lines with increased expression of ribosomal RNA (rRNA) achieved through introduction of nucleic acids encoding UBF or reducing expression of NoRC proteins, especially of TIP-5. Those cell lines have improved secretion and growth characteristics in comparison to control cell lines. The invention further concerns a method of producing proteins using the cells generated by the described method. | 07-26-2012 |
20120258496 | PRODUCTION OF LOW FUCOSE ANTIBODIES IN H4-II-E RAT CELLS - The invention concerns the field of cell culture technology. It specifically concerns a rat hepatoma cell, preferably a H4-II-E rat hepatoma cell, carrying a DNA encoding an antibody or Fc-fusion protein and having low fucosylation activity for adding fucose to glycosidic structures such as biantennary glycans, e.g. N-acetylglucosamine. The invention furthermore concerns a method for producing low fucose glycoproteins especially antibodies or Fc-fusion proteins in rat hepatoma cells, preferably in H4-II-E rat hepatoma cells. It further concerns the identification and generation of new host cell lines which are capable of synthetizing glycoproteins with beneficial properties, improving the therapeutic efficacy and/or serum half-life of the product compared to products from commonly used host cell lines. | 10-11-2012 |
20130177919 | PROTEIN PRODUCTION - The invention concerns the field of protein production and cell culture technology. CERT is identified as a novel in vivo PKD substrate. Phosphorylation on serine 132 by PKD decreases the affinity of CERT towards its lipid target phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity, identifying PKD as a regulator of lipid homeostasis. The present invention shows that CERT in turn is critical for PKD activation and PKD dependent protein cargo transport to the plasma membrane. The interdependence of PKD and CERT is thus a key to the maintenance of Golgi membrane integrity and secretory transport. | 07-11-2013 |
20130196430 | PROTEIN PRODUCTION - The invention concerns the field of protein production and cell culture technology. CERT is identified as a novel in vivo PKD substrate. Phosphorylation on serine 132 by PKD decreases the affinity of CERT towards its lipid target phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity, identifying PKD as a regulator of lipid homeostasis. The present invention shows that CERT in turn is critical for PKD activation and PKD dependent protein cargo transport to the plasma membrane. The interdependence of PKD and CERT is thus a key to the maintenance of Golgi membrane integrity and secretory transport. | 08-01-2013 |
20130197196 | PROTEIN PRODUCTION - The invention concerns the field of protein production and cell culture technology. CERT is identified as a novel in vivo PKD substrate. Phosphorylation on serine 132 by PKD decreases the affinity of CERT towards its lipid target phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity, identifying PKD as a regulator of lipid homeostasis. The present invention shows that CERT in turn is critical for PKD activation and PKD dependent protein cargo transport to the plasma membrane. The interdependence of PKD and CERT is thus a key to the maintenance of Golgi membrane integrity and secretory transport. | 08-01-2013 |
20130210074 | EPIGENETIC ENGINEERING - The invention concerns the field of cell culture technology. It concerns production host cell lines with increased expression of ribosomal RNA (rRNA) achieved through reducing expression of NoCR proteins, especially of TIP-5. Those cell lines have improved secretion and growth characteristics in comparison to control cell lines. | 08-15-2013 |
Igor Kaufmann, Nuernberg DE
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20100119313 | Eight-Edged Cutting Insert, and Tool Holder for Same - The invention relates to an eight-edged rotatable and reversible cutting insert having two opposite, substantially square base surfaces which are twisted relative to one another about a central axis running perpendicularly to said base surfaces, and having four identical side surfaces, wherein a main lip is formed between each base surface and each side surface. A bearing surface is formed between two chip grooves which extend along the associated main lip of the respective side surface, said bearing surface extending symmetrically beyond the groove ends of the adjacent chip groove and transversely to the main lips until its adjoins the latter. | 05-13-2010 |
20100129166 | Eight-Edged Cutting Insert, and Tool Holder for Same - The invention relates to an eight-edged rotatable and reversible cutting insert having two opposite, substantially square base surfaces which are twisted relative to one another about a central axis running perpendicularly to said base surfaces, and having four identical side surfaces. A main lip is formed between each base surface and each side surface and extends only over part of the length of the side surface. Each side surface has two diagonally opposite corner edges which are of circular or curved design and form a secondary lip adjacent to the respective main lip. In addition, each side surface has two chip pockets which are drawn into the side surface and which, starting from the respective corner edge, extend along the main lip assigned to said corner edge up to a rear chip pocket end. | 05-27-2010 |
Igor Kaufmann, Nurnberg DE
Patent application number | Description | Published |
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20100158622 | GROOVING TOOL FOR CUTTING GROOVES IN WORKPIECES AND A GROOVING TOOL TOOL HOLDER FOR PERMITTING REPLACEMENT OF INSERTS AND PERMITTING INSERTS TO BE REPLACED WITHOUT MOVING THE TOOL HOLDER WITH RESPECT TO THE GROOVING TOOL IN WHICH THE TOOL HOLDER IS INSTALLED - A grooving tool for cutting grooves in workpieces and a grooving tool tool holder for permitting replacement of inserts and permitting inserts to be replaced without moving the tool holder with respect to the grooving tool in which the tool holder is installed. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. | 06-24-2010 |
20110293383 | INDEXABLE INSERT - An indexable insert having two main faces ( | 12-01-2011 |
20120269588 | GROOVING INSERT AND METHOD FOR PRODUCING A GROOVING INSERT - A grooving insert comprising a cutting edge ( | 10-25-2012 |
20130236256 | GROOVE INSERT, CLAMPING HOLDER FOR A GROOVE INSERT AND GROOVE CUTTING TOOL - A groove insert to be received in a tool holder has, along its top and bottom side and on its rear side, a holding structure which is formed by holding faces which taper toward one another and by way of which the groove insert is fixed in the tool holder in a positive locking manner. The tool holder has corresponding counter faces. The groove insert and the tool holder form a groove cutting tool. | 09-12-2013 |
20140064864 | TANGENTIAL INDEXABLE CUTTING INSERT - A tangential indexable cutting insert having eight lips which are distributed in pairs over four side faces of the indexable cutting insert, each lip being formed by a main lip which is formed by the intersection of one of the side faces with a base face, a secondary lip, which is formed by the intersection of the side face with an adjacent side face, and a corner edge ( | 03-06-2014 |
20140147219 | CUTTING INSERT HAVING A COOLANT DUCT - A cutting insert having a main lip, a rake face and at least one coolant duct, which is formed on the top side of the cutting insert, is disclosed. The at least one coolant duct runs at least partially in the rake face towards the main lip and the width increases towards the main lip. | 05-29-2014 |
20140161547 | TOOL HOLDER FOR GROOVE CUTTING TOOL, GROOVE INSERT AND GROOVE CUTTING TOOL - A groove cutting tool has a groove insert and a tool holder. The groove insert can be replaced by using a lever tool. The lever tool penetrates into a slot by way of an ejector portion and is able to assume several positions in the slot either in order to contact the groove insert and to push it out of its receiving means or in order to push away a clamping jaw and to open the receiving means for the groove insert. | 06-12-2014 |
20140199129 | TOOLHOLDER AND CUTTING INSERT THEREFOR - A cutting tool ( | 07-17-2014 |
Jens Kaufmann, Berlin DE
Patent application number | Description | Published |
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20090247591 | SUBSTITUTED CYCLOHEXYLDIAMINES - The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain or other conditions. | 10-01-2009 |
Joerg Kaufmann, Berlin DE
Patent application number | Description | Published |
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20100285038 | Factor Involved in Metastasis and Uses Thereof - The present invention is related to a nucleic acid coding for a factor involved in a biological process, whereby the process is a PI 3-kinase pathway regulated process, preferably a process selected from the group comprising glucose metabolism, amino acid and glucose deprivation processes, diabetes, wound healing, stress response, apoptosis, metastasis, tumorigenesis, cell migration, cell motility in extracellular matrix and cell growth in extracellular matrix, and the factor is a polypeptide comprising an amino acid sequence according to SEQ ID. NO. 1 or a polypeptide having a sequence according to databank entries gi 9506687 or NP_061931, preferably NP_061931.1. | 11-11-2010 |
20130196314 | Genes Differentially Expressed in Breast Cancer - A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions. | 08-01-2013 |
20140179755 | USE OF VEGFR1 AS A BIOMARKER - The present invention is related to the use of VEGFR1 or of a nucleic acid coding for VEGFR1 as a biomarker in a method for the treatment of a subject, wherein the method for the treatment comprises administering to the subject a PKN3 inhibitor. | 06-26-2014 |
Jörg Kaufmann, Berlin DE
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20110008320 | Further Use of Protein Kinase N Beta - The present invention is related to use of protein kinase N beta or a fragment or derivative thereof as a downstream target of the PI 3-kinase pathway, preferably as a downstream drug target of the PI 3-kinase pathway. | 01-13-2011 |
20110118456 | Interfering RNA Molecules - The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and whereby said first stretch is at least partially complementary to a target nucleic acid, and the second strand comprises a second stretch of contiguous nucleotides whereby said second stretch is at least partially identical to a target nucleic acid, and whereby the double stranded structure is blunt ended. | 05-19-2011 |
20120022138 | MEANS FOR INHIBITING THE EXPRESSION OF ANG2 - The present invention is related to an siRNA comprising an antisense strand and a sense strand, wherein all or a portion of said antisense strand comprises an antisense duplex region, wherein all or a portion of said sense strand comprises a sense duplex region, wherein said antisense duplex region is at least partially complementary to said sense duplex region, wherein said siRNA comprises a duplex region consisting of said antisense duplex region and said sense duplex region, and wherein: a) said antisense strand comprises a nucleotide sequence of SEQ ID NO: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 68, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102 or 104; or b) said antisense strand comprises an antisense duplex region, all or a portion of which, is complementary to a portion of SEQ ID NO: 1 or 70. | 01-26-2012 |
20120171220 | FURTHER USE OF PROTEIN KINASE N BETA - The present invention is related to use of protein kinase N beta or a fragment or derivative thereof as a downstream target of the PI 3-kinase pathway, preferably as a downstream drug target of the PI 3-kinase pathway. | 07-05-2012 |
Juergen Kaufmann, Neustadt DE
Patent application number | Description | Published |
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20100221127 | Main Coolant Pump - An engine pump assembly ( | 09-02-2010 |
Jurgen Kaufmann, Denzlingen DE
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20080279726 | Cuvette - The invention relates to a cuvette ( | 11-13-2008 |
20120002205 | OPTOELECTRONIC APPARATUS FOR GAS ANALYSIS AND METHOD - The invention relates to an improved optoelectronic apparatus for optical gas analysis by means of which the interfering influence of the particles contained in the gas is reduced with regard to the intended measurement. For this purpose the optoelectronic apparatus in accordance with the invention has a light transmitter and a light receiver which define an optical measurement path including a measurement volume between one another. The received signals of the light receiver can be evaluated in an evaluation unit, to ultimately obtain the desired information therefrom, for example, the concentration of a specific gas content. In accordance with the invention an ionizer is further provided which is arranged upstream of the optical measurement path. The ionizer causes an ionization of the undesirable particles, i.e. e.g. the dust particles, smoke particles or such like aerosols so that the ionized particles can be deflected by electric fields or also magnetic fields by means of an ion acceleration apparatus. In this respect the ion acceleration apparatus and/or its electromagnetic fields is/are aligned such that the generated ions experience a deflection to be able to flow past the measurement volume. | 01-05-2012 |
Jürgen Kaufmann, Denzlingen DE
Patent application number | Description | Published |
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20120002205 | OPTOELECTRONIC APPARATUS FOR GAS ANALYSIS AND METHOD - The invention relates to an improved optoelectronic apparatus for optical gas analysis by means of which the interfering influence of the particles contained in the gas is reduced with regard to the intended measurement. For this purpose the optoelectronic apparatus in accordance with the invention has a light transmitter and a light receiver which define an optical measurement path including a measurement volume between one another. The received signals of the light receiver can be evaluated in an evaluation unit, to ultimately obtain the desired information therefrom, for example, the concentration of a specific gas content. In accordance with the invention an ionizer is further provided which is arranged upstream of the optical measurement path. The ionizer causes an ionization of the undesirable particles, i.e. e.g. the dust particles, smoke particles or such like aerosols so that the ionized particles can be deflected by electric fields or also magnetic fields by means of an ion acceleration apparatus. In this respect the ion acceleration apparatus and/or its electromagnetic fields is/are aligned such that the generated ions experience a deflection to be able to flow past the measurement volume. | 01-05-2012 |
Karl Kaufmann, Poing DE
Klaus Kaufmann, Wuppertal DE
Patent application number | Description | Published |
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20110302763 | DEVICE FOR ATTACHING A LINE TO A CONNECTING ELEMENT - A device for attaching a line or wire cable to a connecting element includes an upper and a lower die that each has a press surface. At least one recess outside of the press surfaces is provided between the upper and the lower die that decreases the risk of damage to the dies should an erroneous attachment of the wire cable to the connecting element occur. | 12-15-2011 |
Marita Kaufmann, Griesheim DE
Patent application number | Description | Published |
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20080292893 | Heat-Sealing Material for Aluminum Foils and Polyethylene Terephthalate Foils Against Polypropyl, Polyvinyl Chloride, and Polystyrol Containers - The invention relates to a heat-sealable coating system suitable for the sealing of various types of substrate and comprising a film-forming dispersion, | 11-27-2008 |
20110111238 | IMPROVED ADHESIVE AGENTS FOR PLASTISOLS - The invention relates to plastisols which even without the addition of adhesion promoters exhibit high adhesion to metallic and cathodically deposition-coated substrates. | 05-12-2011 |
Markus Kaufmann, Berlin DE
Patent application number | Description | Published |
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20090220918 | AUTOMATIC CROWN AND GINGIVA DETECTION FROM THREE-DIMENSIONAL VIRTUAL MODEL OF TEETH - A method is provided for automatically separating tooth crowns and gingival tissue in a virtual three-dimensional model of teeth and associated anatomical structures. The method orients the model with reference to a plane and automatically determines local maxima of the model and areas bounded by the local maxima. The method automatically determines saddle points between the local maxima in the model, the saddle points corresponding to boundaries between teeth. The method further positions the saddle points along a dental arch form. For each tooth, the method automatically identifies a line or path along the surface of the model linking the saddle points to each other, the path marking a transition between teeth and gingival tissue and between adjacent teeth in the model. The areas bounded by the lines correspond to the tooth crowns; the remainder of the model constitutes the gingival tissue. | 09-03-2009 |
20100153075 | METHOD AND SYSTEM FOR FINDING TOOTH FEATURES ON A VIRTUAL THREE-DIMENSIONAL MODEL - A method and system are disclosed for finding virtual tooth features on virtual three-dimensional models of the teeth of patients. The tooth features comprise marginal ridges, cusp tips, contact points, central groove and buccal groove. Tooth axes system plays a key role in identifying the tooth features. An iterative method is disclosed for improving the accuracy of the tooth axes system. A virtual three-dimension model preferably obtained by scanning the dentition of a patient forms the basis for determining the tooth features. Tooth features are derived for all categories of teeth including molars, premolars, canines and front teeth. Tooth features are very helpful and used in planning orthodontic treatment. The tooth features are determined automatically using the computerized techniques; and can be manually adjusted when necessary. | 06-17-2010 |
20110268327 | GENERATING THREE DIMENSIONAL DIGITAL DENTION MODELS FROM SURFACE AND VOLUME SCAN DATA - A method and apparatus are disclosed enabling an orthodontist or a user to create an integrated three dimensional digital model of dentition and surrounding anatomy of an orthodontic patient from a three-dimensional digital model obtained using a scanner with a three-dimensional digital model obtained using a Cone Beam Computed Tomography (CBCT) or Magnetic Resonance Tomography (MRT) imaging devices. The digital data obtained from scanning as well as from CBCT imaging are downloaded into a computer workstation, and registered together in order to create a comprehensive 3-D model of the patient's teeth with roots, bones and soft tissues. The invention provides substantial improvement over the traditional two dimensional imaging modalities such as x-rays, photographs, cephalometric tracing for diagnosis and treatment planning | 11-03-2011 |
20110269097 | Method and system for comprehensive evaluation of orthodontic care using unified workstation - A method and system for orthodontic treatment planning, evaluation and quality measurement is provided comprising a workstation having computing platform, a graphical user interface, a processor and a computer storage medium containing digitized records pertaining to a patient. The digitized records include image and other types of data. The computer storage medium further includes a set of software instructions providing graphical user interface tools for providing a user with access to the digitized records for planning orthodontic treatment of a patient. Also provided are reference databases for aiding in the decision process during treatment selection, treatment planning and treatment delivery and progress monitoring and evaluation. Also provided are parameter or criteria measurement techniques and generally acceptable thresholds, which can be updated through learning process and through acquisition of patient data. Once the treatment is planned, the virtual dentition model of the patient in the proposed treatment set-up or the target state is evaluated using several virtual model evaluation features and criteria. | 11-03-2011 |
20120015316 | UNIFIED THREE DIMENSIONAL VIRTUAL CRANIOFACIAL AND DENTITION MODEL AND USES THEREOF - A method and apparatus are disclosed enabling an orthodontist or a user to create an unified three dimensional virtual craniofacial and dentition model of actual, as-is static and functional anatomy of a patient, from data representing facial bone structure; upper jaw and lower jaw; facial soft tissue; teeth including crowns and roots; information of the position of the roots relative to each other; and relative to the facial bone structure of the patient; obtained by scanning as-is anatomy of craniofacial and dentition structures of the patient with a volume scanning device; and data representing three dimensional virtual models of the patient's upper and lower gingiva, obtained from scanning the patient's upper and lower gingiva either (a) with a volume scanning device, or (a) with a surface scanning device. Such craniofacial and dentition models of the patient can be used in optimally planning treatment of a patient. | 01-19-2012 |
20140188448 | ORTHODONTIC TREATMENT PLANNING USING VIRTUAL ARTICULATOR - The present invention discloses orthodontic treatment planning using virtual articulator with the help of a computer workstation. | 07-03-2014 |
Martin Kaufmann, Heidelberg DE
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20120060712 | METHOD FOR SETTING THE INKING IN PRINTING PRESSES - A method for controlling the inking in printing presses having at least one control computer and at least one printing unit with an inking unit and a dampening unit, includes carrying out settings for controlling the inking in the inking unit and/or dampening unit of the printing press through the use of the control computer. The settings are displayed on a display device and the settings that are carried out are recorded and stored periodically by the control computer. | 03-15-2012 |
Matthias Kaufmann, Ringsheim DE
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20080202566 | INDUSTRIAL DISHWASHER - Industrial dishwasher with a main blower and an additional blower and a drying channel, wherein, in the base, the drying channel has a drainage means which runs transversely to the channel base and has a drainage opening, the channel base sloping up in the direction of the drainage means. | 08-28-2008 |
20110017235 | DISHWASHER AND METHOD FOR CLEANING WASH WARE - The invention relates to a dishwasher ( | 01-27-2011 |
Michael Kaufmann, Ellwangen DE
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20110308827 | Power Screwdriver - A power screwdriver is disclosed, having a drive for driving a tool spindle having a controller for controlling the drive, having a monitoring device for monitoring the rotation speed or the torque, and having a monitoring device for monitoring a switch-off criterion, which monitoring device is coupled to the controller, in order to switch off the drive when the switch-off criterion is reached, with the controller being programmed such that (a) the drive is first of all accelerated until the rotation speed has reached a specific first rotation speed; (b) if the rotation speed then falls by at least a specific amount within a specific time increment, or the torque rises by at least a specific amount within a specific time increment, the drive is braked until the rotation speed has reached a specific second rotation speed, which is lower than the first rotation speed; (c) the drive is then regulated at the second rotation speed for a specific time; and (d) after step (c), the drive is accelerated again at most until the rotation speed reaches the first rotation speed. | 12-22-2011 |
20120019177 | Power Tool Having An Electric Brake - The invention relates to a method for decelerating a drive movement of a power tool and to a power tool suitable for carrying out the method, having a drive driven by a motor, an energy supply device for the provision of electrical energy, a controller having a motor controller for activating the motor and an operating-state recognition module which is to detect at least one operating-state variable and, as a function of this, to output a brake signal, the controller being designed to initiate, as a function of the brake signal, a braking procedure in which brake cycles are provided which have a first time segment, in which the motor is short-circuited, and a second time segment in which current is fed to the motor opposite to its original direction of rotation. | 01-26-2012 |
Michael Kaufmann, Wachtersbach DE
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20100198152 | CANNULA DEVICE HAVING PIVOTABLE NEEDLE GUARD - A cannula device having a base body made of plastic, on which a cannula is held, and having a guard element that can be moved relative to the base body into a second position, in which the cannula tip is exposed for the use of the cannula device, from a first position, in which, in the delivered state of the cannula device, the cannula tip is covered to protect the user from injury. The guard element is movable, after use of the cannula device, back into a third position in which the cannula tip is covered to protect a user from injury, and the guard element is irreversibly locked to the base body by a third fixing device including a first latching protrusion protruding from the base body and at least one first latching receptacle, associated with the first latching protrusion in at least one side wall of the guard element. | 08-05-2010 |
Michael Kaufmann, Gehrden DE
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20100015841 | Electric plug connector having a guiding - The invention relates to a plug ( | 01-21-2010 |
20130186211 | Sensor Mounting for a Distance Sensor - The invention relates to a sensor mounting ( | 07-25-2013 |
Michael Kaufmann, Kempten DE
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20090046484 | Power supply for an electronic system - According to prior art, a clock frequency increase for clocked high-frequency integrated circuits, in particular microprocessors, reaches a current physical limit of approximately 3 GHz, as dynamic current modifications cannot be sufficiently compensated. The aim of the invention is to provide a power supply for electronic systems with a double-figure GHz range. To permit the rapid compensation of dynamic current modifications, the current compensation circuit ( | 02-19-2009 |
Michael Kaufmann, Meckenheim DE
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20110308212 | Filter Element and Filter System - The invention relates to a filter element, comprising a filter medium ( | 12-22-2011 |
20120317939 | Air Filter Element, Filter Housing and Filter Arrangement - An air filter element ( | 12-20-2012 |
20120317943 | Filter element and housing for a filter element - A filter element ( | 12-20-2012 |
20120324849 | Filter Element for Fluid Filtration, in Particular for Intake Air of Internal Combustion Engines - A filter element ( | 12-27-2012 |
20140059986 | Filter Arrangement and Method for Producing a Filter Receptacle - A filter arrangement has a filter receptacle and a round filter element arranged in the filter receptacle. The filter receptacle has a substantially cylindrical housing part with a cylindrical wall. An inflow opening is arranged in the cylindrical wall. An inflow socket is connected to the inflow opening and adapted to couple a fluid supply line. An axial outflow opening is connected to the cylindrical housing part. The inflow socket has a flow cross-section that widens in a flow direction into an interior of the cylindrical housing part. | 03-06-2014 |
20140102058 | Air filter system, air filter element and method for exchanging an air filter element | 04-17-2014 |
20140109532 | Filter - An air filter has a hollow cylindrical filter housing having a first axial terminal area and a second axial terminal area and a cylindrical outer filter housing wall and a ring-shaped flow guiding wall. The ring-shaped flow guiding wall extends coaxially to the cylindrical outer filter housing wall in the interior of the filter housing. A ring-shaped flow space is formed between outer filter housing wall and flow guiding wall. A filter element of an annularly closed filter medium is disposed in the filter housing. The flow guiding wall surrounds the filter element. An inlet socket is arranged on the outer filter housing wall in the first axial terminal area and extends tangentially relative thereto. The inlet socket has a projection that projects into the ring-shaped flow space and bridges the ring-shaped flow space up to the flow guiding wall. | 04-24-2014 |
20140165834 | Air filter system, air filter element and method for exchanging an air filter element - An air filter system, in particular for the intake air of internal combustion engines, is provided. It comprises a housing with a housing upper part and a round air filter element for filtering air, the housing comprising a clean air connection for discharging clean air from the housing and an annular sealing groove axially opened towards the interior area of the housing surrounding the clean air connection for the engagement of an annular sealing web axially extending away from the filter element, the sealing groove featuring a cylindrical contact area to which a sealing surface of the sealing web can be applied in particular radially sealingly, wherein the sealing groove features a cylindrical support area facing the contact area and the support area features at least one extension protruding from the support area in the direction of the sealing surface, wherein the sealing web features a second surface opposite to the sealing surface that features several annularly surrounding indentations in radial direction, wherein the at least one extension engages respectively one of the indentations. | 06-19-2014 |
20150013281 | Air Filter Element, Filter Housing and Filter Arrangement - An air filter element ( | 01-15-2015 |
20150059296 | Filter Element and Filter System with a Filter Element - A filter element has a filter body having a longitudinal axis, wherein the filter body has a first end with a first end face and a second end with a second end face opposite the first end in direction of the longitudinal axis. The filter body is provided with inner and outer circumferential surfaces permeable for a medium to be filtered. A first end disk is arranged at the first end face and a second end disk is arranged at the second end face. The outer circumferential surface of the filter body has at least one fluid-tight area that is impermeable for the medium to be filtered. The fluid-tight area is an incoming flow protector or an improper handling protector resting on the outer circumferential surface. | 03-05-2015 |
20150059297 | Air filter system and air filter element for an air filter system - A filter system for intake air of an internal combustion engine has a housing with a cover. A filter element is arranged in the housing. An inlet feeds a medium to be filtered into the housing and an outlet discharges the medium from the housing. The filter element has a filter body with first end face and opposite second end face. The filter element has an open first end plate at the first end face and a second end plate at the second end face. A support tube is arranged concentrically about a longitudinal axis in the housing and attached with a first end to the housing. The support tube is arranged in the interior of the filter element and radially supports the filter body. The second end plate rests on the second end of the support tube and on an inner cover contour of the cover with anti-rotation action. | 03-05-2015 |
20150059301 | Filter system with filter element - A filter system is provided with a housing having a housing wall and a cover, the housing having a longitudinal axis. An inlet is arranged on the housing and feeds a fluid to be filtered into the housing. An outlet is arranged on the housing and discharges the filtered fluid. Filter elements each having at least one filter medium are arranged in the housing. At least one of the filter elements extends along the longitudinal axis. The filter medium has pleats extending along the longitudinal axis with outer and inner pleat edges. The outer pleat edges extend on the first side of the filter medium and the inner pleat edges on the second side of the filter medium and are opposite the outer pleat edges. The filter medium has a variable flow resistance along the longitudinal axis. | 03-05-2015 |
20150059302 | Filter System Having a Support Tube - A filter system has a housing with a housing wall and at least one cover. An inlet port is arranged on the housing and supplies a fluid to be filtered to the housing. An outlet port is arranged on the housing and discharges the fluid that has been filtered from the housing. A support tube is arranged in an interior of the housing and accommodates a filter element. The support tube extends along a housing axis of the housing and has a receiving side, wherein the support tube is connected to the housing by a first detent connection provided on the receiving side. | 03-05-2015 |
20150059304 | Filter Element and Filter System with a Filter Element - A filter element has a filter body with a first end face and a second end face opposite the second end face in a direction of a longitudinal axis of the filter body. A first open end plate is arranged at the first end face. A second closed end plate is arranged at the second end face. The second end plate has a sealing structure and the sealing structure is adapted to seal, when the filter element is installed in a housing, a region between the second end plate and a cover of the housing relative to an interior space of the housing. The sealing structure is a ring surrounding an outside circumference of the second end plate and has a sealing surface directed in radial direction outwardly. | 03-05-2015 |
20150059584 | Filter system with sensor socket - A filter system has a housing with a housing wall and at least one lid. An inlet socket is arranged at the housing and feeds a fluid to be filtered into the housing. An outlet socket is arranged at the housing and discharges the fluid that has been filtered from the housing. A sensor socket is arranged at an end section of the housing. The sensor socket is arranged angularly relative to a longitudinal axis of the housing at the outlet socket. | 03-05-2015 |
20150060351 | Filter System with Seal - A filter system has a housing with a housing wall and at least one cover. An inlet is arranged on the housing and feeds a liquid to be filtered into the housing. An outlet is arranged on the housing and discharges the liquid that has been filtered from the housing. At least one filter element is arranged between the inlet and the outlet and separates a raw side of the filter system from a clean side of the filter system. A gasket is arranged between a sealing surface of the housing wall and a sealing surface of the cover. The gasket is held in position in a longitudinal direction of the housing by at least one retaining element that is arranged on the cover or on the housing wall. | 03-05-2015 |
20150082982 | Filter Element and Filter System Having a Filter Element - The invention relates to a filter element ( | 03-26-2015 |
Michaela Kaufmann, Schwelm DE
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20100120145 | THREE-DIMENSIONAL BIOCOMPATIBLE SKELETON STRUCTURE CONTAINING NANOPARTICLES - The invention relates to a cell culture system comprising a three-dimensional, biocompatible frame structure and biocompatible nanoparticles, a method for the cultivation of cells, and the preparation of cells or cell products and tissues per se by means of such a cell culture system. | 05-13-2010 |
20110300530 | IN VITRO TEST SYSTEM FOR VIRAL INFECTIONS - The invention relates to a multi-layered biological in vitro tissue containing: dermis layer, containing a collagen biomatrix with fibroblasts embedded therein and epidermis layer, containing epithelial cells. It is provided that latently virally infected neuronal cells are integrated at least into the dermis layer. | 12-08-2011 |
20120058560 | Bioreactor System - Bioreactors may be used for the cultivation of cells, in particular of adherent cells, and, in particular for the cultivation and propagation of cell cultures, and utilized in methods for the cultivation of cells. A particular area of application is the use of the bioreactors in the GMP-compliant, fully automatic cultivation and propagation of cells. | 03-08-2012 |
Michael W. Kaufmann, Stuttgart DE
Patent application number | Description | Published |
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20110302367 | Write Buffer for Improved DRAM Write Access Patterns - The present invention relates to a method and respective system for operating a DRAM main memory. One buffer line is provided for multiple pages. When writing data to the buffer it is decided which to which buffer-line the data is written to based on its destination main memory address. A tuple consisting of lower memory address and data is stored. Data entered into the buffer-line will be sorted by page in case the line is flushed to the main memory. Sorting the buffer entries results in less page openings and closings, since the data is re-arranged by memory address and therefore in logical order. By using one line for multiple pages only a fraction of memory of a common set-associative cache is needed, thus decreasing the amount of overhead significantly. | 12-08-2011 |
20120158774 | Computing Intersection of Sets of Numbers - The present invention relates to a computer program product, method and system for computing set intersection of a first and a second unordered set of discrete members that stem from a known input range of consecutive discrete numbers. The method breaks the numbers into subranges and for each subrange, utilizes a bit vector in a first random access memory, directly addressing bits representing values in a subrange in the first set to values in the second set in the subrange and writing each number of the second set that is also set member of the first set in the sub range directly to an output. This may be utilized by various applications including database applications. The algorithm may be offloaded to one or more processing subsystems. | 06-21-2012 |
Oliver Kaufmann, Heidenheim DE
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20080211514 | METHOD AND APPARATUS FOR DETERMINING THE MOISTURE OF A RUNNING MATERIAL WEB - In a method for determining the moisture of a running material web, in particular a paper web or paperboard web, the material web is scanned by way of a sensor including a microwave resonator, the resonance response of the microwave resonator is investigated, and the moisture in the material web is established in the light of this resonance response while taking account of the distance between the microwave resonator and the material web. Also disclosed is a corresponding apparatus for determining the moisture. | 09-04-2008 |
20090199987 | METHOD FOR DEWATERING AND A DEWATERING APPARATUS - This invention relates to a dewatering apparatus, in particular a paper machine or a paperboard machine, for the adjustable, and controllable dewatering of a fibrous material, which is conveyed as a fibrous web that can be divided into at least two zones arranged side by side in a cross direction (CD). The dewatering apparatus is characterized in that the dewatering of the fibrous material is adaptable to a dewatering curve defined in a machine direction on the basis of measurements of the water weight of the fibrous material taken by at least two water weight sensors, in particular a one-dimensional or multi-dimensional sensor arrangement of water weight sensors, which are assigned to a zone and arranged preferably in pairs in mutually offset position in the CD direction. | 08-13-2009 |
20100141270 | PROCESS AND DEVICE TO MEASURE AT LEAST ONE QUALITATIVE VALUE OF A FIBROUS WEB - A process to measure at least one qualitative measure of a moving fibrous web. The fibrous web being a web of paper or cardboard. The process including the steps of influencing, evaluating and determining. The influencing step includes the influencing of at least one microwave resonator by the fibrous web. The evaluating step including the evaluating of at least one resonance curve of the at least one microwave resonator. The determining step including the determining of at least one quality measure of the fibrous web dependent upon results of the evaluating step. | 06-10-2010 |
20110024069 | METHOD FOR OPTIMIZING THE ENERGY BALANCE IN FORMING SECTIONS IN MACHINES FOR THE PRODUCTION OF FIBROUS WEBS, AND FORMING SECTION - The invention relates to a method for optimizing the energy balance of a forming section in a machine for producing fibrous webs, in which a fiber suspension, which is fed to the forming section by way of a material ramp after the immobility point is reached, is passed through at least two dewatering units within a compression zone and to a subsequent functional unit. The invention is characterized in that a setpoint value for a target dryness to be set is predefined based on the existing dewatering elements as a function of a theoretical maximum achievable dryness under plant conditions in the area of the transition zone, said setpoint being selected such that it is less than the theoretical maximum achievable dryness but is equal to or greater than a required minimum dryness in the area of the transition zone, and that the target dryness is controlled by lowering the inlet dryness at one of the last dewatering units disposed in the direction of passage of the fiber suspension within the compression zone. | 02-03-2011 |
20120145346 | METHOD FOR OPTIMIZING THE ENERGY BALANCE IN FORMING SECTIONS IN MACHINES FOR THE PRODUCTION OF FIBROUS WEBS, AND FORMING SECTION - A forming section in a machine for producing a web of fibrous material includes a control and/or regulating system including a control and/or regulating device which is connected with at least one device for at least indirect acquisition of one value at least indirectly characterizing the dry content of the fibrous web in a transfer area from the forming section to a following function unit, with a device for input of a desired value for the target dry content, and with at least the control elements of an individual dewatering unit located prior to one of the last dewatering units, or the last dewatering unit inside the compression zone. The control and/or regulating device also includes a device for creating the control variables for controlling the individual dewatering units. | 06-14-2012 |
Paul Kaufmann, Aalen DE
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20110013171 | PROJECTION EXPOSURE SYSTEM FOR MICROLITHOGRAPHY WITH A MEASUREMENT DEVICE - A projection exposure system ( | 01-20-2011 |
Peter Kaufmann, Moers DE
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20100058732 | COMBUSTION CHAMBER FOR A GAS TURBINE - A combustion chamber for a gas turbine is provided. The combustion chamber comprises at least one first and one second jet carrier, of which at least one is provided for injecting an operating gas in the combustion chamber such that waste gas fanned in the flame zone thereof is circulated to a mixing zone of the first jet carrier. In order to achieve a compact combustion chamber, the jet carriers are positioned in relation to each other such that waste gas from the flame zone of the first jet carrier flows directly to the mixing zone of the second jet carrier. | 03-11-2010 |
20100300104 | BURNER, OPERATING METHOD AND ASSEMBLY METHOD - A burner incorporating a pilot cone and a mounting insert is provided. The pilot cone is constructed as a pilot cone assembly which is decoupled from the mounting insert. Further, an operating method for increasing the service life of a burner which incorporates a pilot cone assembly and a mounting insert is provided. The pilot cone assembly has a cone side and incorporates at least one further side where the further side is arranged to be essentially parallel to one of the sides of the mounting insert and spaced apart from it, so that between the further side and the side of the mounting insert there is a defined gap. In an operation of the burner, the gap is significantly reduced by the thermal expansion in at least at one point of contact between the further side and the side of the mounting insert. Finally, an assembly method is provided. | 12-02-2010 |
20120015311 | BURNER FOR A GAS COMBUSTOR AND A METHOD OF OPERATING THE BURNER THEREOF - A burner for a gas combustor and a method of operating the burner are disclosed. The burner includes a front surface area divided into a plurality of subareas and inlets arranged on the front surface area such that each subarea is encircled by at least four inlets and such that during operation of the burner, a gas recirculation in the combustor is facilitated corresponding to each subarea. | 01-19-2012 |
20130232988 | BURNER FOR A GAS COMBUSTOR AND A METHOD OF OPERATING THE BURNER THEREOF - A burner for a gas combustor and a method of operating the burner are disclosed. The burner includes a front surface area divided into a plurality of subareas and inlets arranged on the front surface area such that each subarea is encircled by at least four inlets and such that during operation of the burner, a gas recirculation in the combustor is facilitated corresponding to each subarea. | 09-12-2013 |
Peter Matthias Kaufmann, Wedemark DE
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20090130699 | METHOD FOR TESTING SUBSTANCES ON BIOMATRICES - The invention relates to a method for testing one or several substances. According to said method, a tissue equivalent is cultivated, the substance/s is/are made to affect the tissue equivalent, and it is determined whether the effect of the substance/s has resulted in a modification of the tissue equivalent and/or the substance/s. The tissue equivalent comprises at least one cell and a porous matrix based on a biologically compatible polymer or polymer mixture. The matrix is provided with pores having a maximum size of 150 μm as well as pores having a minimum size of 300 μm while the degree of porosity is 93 to 98 percent. | 05-21-2009 |
20100028405 | MATRIX, CELL IMPLANTATION AND METHOD FOR THEIR PRODUCTION AND USE - The invention relates to porous matrices based on a biologically compatible polymer or polymer mixture, to a cell implantation that is established on said matrices and to additional cell implantation based on cell mixtures of hepatocytes and islets of Langerhans. The invention also relates to a method for producing porous matrices, to matrices obtained according to said method and to a special method for obtaining cells for the inoculation of an implantable matrix. | 02-04-2010 |
Rainer Kaufmann, Stuttgart DE
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20110159339 | BATTERY WITH A HEAT CONDUCTING PLATE - The invention relates to a battery with a heat conducting plate for controlling the temperature of the battery. The battery comprises a plurality of single cells connected in parallel and/or in series to each other, the cells being connected to the heat conducting plate in a heat conducting manner. In the heat conducting plate, a channel structure for a heat conducting medium is provided. In the region of the poles of the single cells, the heat conducting plate comprises bores through which the poles of the single cells extend. | 06-30-2011 |
20120177977 | Battery with a Stack of Bipolar Individual Battery Cells - A battery includes a stack of bipolar individual battery cells, each of which includes an electrode stack and two sheet metal covers bounding the individual battery cell at least in the stacking direction. The electrode stack is connected to at least one of the sheet metal covers by at least one weld. In the region of the at least one weld, the sheet metal cover welded to the electrode stack and/or the sheet metal cover of the adjacent individual battery cell in contact with the sheet metal cover is/are of a set-back design. As a result, the sheet metal covers of adjacent individual battery cells do not have any contact in the region of the at least one weld. | 07-12-2012 |
20120208065 | Single Cell For a Battery - A single cell for a battery that includes a first housing part and a second housing part, which are electrically isolated from one another by an insulating housing frame. An electrochemically-active material is located in housing frame between housing parts. The first housing part and second housing part are in the form of plates. At least one of the housing parts exhibits a first edge area bent over towards the inside, and first housing part and second housing part are fixed by a form fit to one-piece housing frame. | 08-16-2012 |
20130045409 | Battery Having a Plurality of Single Cells - A battery is provided with a plurality of individual cells connected in series and/or in parallel to one another, and at least one cooling plate arranged on the pole side on the individual cells, with current drain tabs of electric poles of the individual cells being thermally coupled with the cooling plate and being angled such that they extend parallel to the cooling plate. Current drain tabs of adjacent individual cells are electrically interconnected in non-positive and/or in positive manner and pressed with the cooling plate in non-positive and/or in positive manner by clamping elements. | 02-21-2013 |
20140220409 | Individual Cell for a Battery, and a Battery - A single cell for a battery includes an electrode foil stack situated in a housing formed from two enveloping metal sheets and a frame that electrically insulates the two enveloping metal sheets from one another. Current discharge tabs of electrode foils of one polarity are connected to one another to form a pole contact, and the respective pole contact is connected to an enveloping metal sheet, and an enveloping metal sheet in each case forms an electrical pole of the single cell. The current discharge tabs of the same polarity are led out in each case at a pole side of the electrode foil stack and connected to one another in a middle area of the pole side. The pole contacts are angled parallel to the pole side, in particular with respect to one-half of the particular pole side, and are connected to an enveloping metal sheet. | 08-07-2014 |
20140242446 | Single Cell for a Battery, and a Battery - A single cell for a battery includes two housing parts, a cell frame, an electrode foil stack situated between the housing parts, and an insulating element situated between the housing parts. The insulating element electrically separates the two housing parts from one another. The insulating element has dimensions such that in the assembled state of the single cell the insulating element projects, at least in part, beyond a first housing part at the edge, forming a projection. The first housing part is enclosed, at least in part, by the insulating element at an edge. | 08-28-2014 |
20140363704 | Battery Comprising a Number of Individual Cells Connected Electrically to One Another and Method for Maintaining, Repairing and/or Optimizing such a Battery - A battery includes a number of single cells interconnected in series and/or in parallel, the electrical poles of which for the electrical interconnection are connected to one another in a positive-fit and/or integrally bonded manner, directly or by means of cell connectors. The battery also includes a battery monitoring unit connected to the electrical poles and/or to the cell connectors in a positive-fit and/or integrally bonded manner. The electrical poles of the single cells, the cell connectors, and/or the battery monitoring unit have redundant contact areas for the positive-fit and/or integrally bonded connection. In each case only one of the contact areas which are redundant with one another is connected in a positive-fit and/or integrally bonded manner, and the further contact area(s) is/are not connected. | 12-11-2014 |
Rainer Kaufmann, Delmenhorst DE
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20100008711 | DRY ERASE INK FOR NON-POROUS SURFACES - A dry-erase ink is disclosed for writing or marking on glossy and non-porous surfaces, in particular whiteboards or dry-erase boards, which ink is wipeable or erasable after drying without leaving visible colored residues. The ink contains a solvent, one or more dye(s) soluble in the solvent, a film forming resin such as polyvinylpyrrolidone or a derivative thereof, a strongly-alkaline substance such as a diamine and/or a quaternary organic ammonium hydroxide, an organic acid or a salt thereof and, if desired, a nonvolatile, liquid component serving as a release agent. | 01-14-2010 |
Ralf Kaufmann, Loerrach DE
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20110257649 | Electrode For An Electrophysiological Ablation Catheter - An electrode for an electrophysiological ablation catheter including an electrode body extending along a longitudinal axis, the electrode body including an electrode outer surface for emitting high-frequency signals and/or for measuring physiological signals, a first attachment point on a first end, at which the electrode is attached to a first catheter shaft, an irrigation lumen extending parallel to the longitudinal axis and through which cooling agent may be directed out of the first catheter shaft and into the electrode, and which forms an opening at the first end of the electrode body, the opening connected to a lumen of the first catheter shaft, and at least one cooling-agent passage connected to the irrigation lumen, the cooling-agent passage situated at an angle to the longitudinal axis and forming first and second openings in the electrode outer surface, through which the cooling agent may be released into the surroundings, as cooling-agent flow. | 10-20-2011 |
20130150805 | Irrigation Catheter Device and Ablation System - An irrigation catheter device, in particular an ablation catheter, including a catheter body in which a central lumen extends from a proximal region into a distal region, wherein a large number of irrigation channels extend away from the lumen, the outlet openings of which out of the catheter body are distributed across the distal end region thereof, wherein sensors are assigned to the central lumen and/or the individual irrigation channels for pressure measurement and/or to measure the flow velocity, to which evaluation means are connected, which are designed to determine the open or closed state of a portion of the irrigation channels on the basis of measured values registered by the sensors. | 06-13-2013 |
20130158478 | Catheter and Method for Producing the Same - A catheter comprising a steering cable anchor, which is preferably disposed at the distal end of the catheter, and a steering cable. In order to obtain a reliable connection between the steering cable anchor and the steering cable, which is also suitable for use in MRI, a substantially dumbbell-shaped element is disposed between the steering cable anchor and the steering cable and connects the steering cable anchor to the steering cable. | 06-20-2013 |
Ralf Kaufmann, Rangendingen DE
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20080288043 | DELIVERY SYSTEM HAVING A SELF-EXPANDING BRAIDED STENT - An insertion system with a self-expanding braided stent ( | 11-20-2008 |
20090030496 | INSERTION SYSTEM FOR STENTS, COMPRISING TENSION-COMPRESSION KINEMATICS - The present invention relates to a device for inserting a self-expanding stent into a body vessel. The device comprises a tube, a pushing element and a grip having a housing via which the pushing element is secured on the grip. Further, the device comprises a stent carrier and a moveable element, the latter of which is guided in the housing of the grip and is coupled to the pushing element. Moving the movable element in the proximal direction effects a movement of the pushing element in the distal direction and a movement of the tube in the proximal direction. | 01-29-2009 |
20090216307 | BRAIDED STENT TO BE IMPLANTED IN A BLOOD VESSEL - A braided stent to be implanted in a blood vessel comprises a hollow body which is stretchable in its longitudinal direction and whose circumferential surface is formed by a braid of a multiplicity of filamentary elements which, in the expanded state of the braided stent, intersect a plane, perpendicular to the longitudinal direction, at a braiding angle. The braided stent has a smaller braiding angle in a central portion than in its distal and proximal portions which adjoin the central portion in the longitudinal direction. | 08-27-2009 |
Regine Kaufmann, Neuwied DE
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20110313372 | Transdermal administration of memantine - The invention relates to transdermal therapeutic systems (TTS) which include, as active ingredient, the NMDA receptor antagonist memantine or one of its physiologically compatible salts. The TTSs can be produced and used for treating diseases of the central nervous system. | 12-22-2011 |
20120065599 | Transdermal Therapeutic System Having Controlled Active Substance Flow Comprising a Basic Reacting Oxide - The present invention relates to transdermal therapeutic systems that include an occlusive back layer impervious to an active substance, a single or multilayer matrix, and a peelable protective film. The matrix or at least one of the matrix layers includes a pharmaceutical active substance or a plurality of pharmaceutical active substances in the form of at least one pharmaceutically consumable salt thereof and a pharmaceutically consumable, alkaline reacting oxide. | 03-15-2012 |
20120225103 | Transdermal Therapeutic System Containing a Pramipexol Active Agent - This invention relates to a transdermal therapeutic system (TTS) releasing an active pramipexol agent during a time ranging from 4 to 7 days. | 09-06-2012 |
Richard Kaufmann, Freudenstadt DE
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20080245110 | Yarn Processing System and Yarn Feeding Device - The invention relates to a yarn processing system S with a textile machine T, a carrying device P, comprising a round cross-section or square cross-section clamping profile | 10-09-2008 |
Sebastian Kaufmann, Plizhausen DE
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20110220621 | Determining Powder Feed Nozzle Misalignment - This invention relates to a method for determining misalignment of a powder feed nozzle and a laser beam. The method includes forming a test structure on a workpiece in at least two different directions by deposition laser welding with powder at substantially constant deposition parameters without relative rotation between a powder feed nozzle and a laser beam, measuring heights and/or wall thicknesses of the test structure along the test structure, and determining a direction and/or an amount of misalignment of the powder feed nozzle relative to the laser beam based on the measured heights and/or wall thicknesses. | 09-15-2011 |
Stefan Kaufmann, Berlin DE
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20100143416 | Alpha-defensins as anthrax immunotherapeutis - The present invention relates to the use of an alpha-defensin in the manufacture of a medicament for the treatment, amelioration or prevention of a disease caused by | 06-10-2010 |
Stefan H.e. Kaufmann, Berlin DE
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20120027794 | TUBERCULOSIS VACCINE WITH IMPROVED EFFICACY - The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules, vectors containing said nucleic acid molecules, cells transformed with said nucleic acid molecules and polypeptides encoded by said nucleic acid molecules. | 02-02-2012 |
20130280739 | DETERMINATION OF THE EFFICACY OF AN ANTI-MYCOBACTERIAL VACCINATION - The invention relates to methods and reagents for determining efficacy of vaccine, particularly of a tuberculosis vaccine. | 10-24-2013 |
20130337011 | RECOMBINANT MYCOBCTERIUM AS A VACCINE - The invention relates to a recombinant | 12-19-2013 |
Stefan H. E. Kaufmann, Berlin DE
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20080280848 | Structures of Active Guide Rna Molecules and Method of Selection - The present invention relates to methods and compositions for modulating RNA silencing efficiency by providing selective RISC (RNA-induced silencing complex) formation. The present invention also relates to methods for identifying nucleic acids and/or determining their structures. | 11-13-2008 |
Stefanie Kaufmann, Hilzingen DE
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20100217395 | INTERVERTEBRAL IMPLANT WITH KEEL - An intervertebral implant component of an intervertebral implant includes an outer surface for engaging an adjacent vertebra and an inner surface. A keel extends from the outer surface and is designed to be disposed in a slot provided in the adjacent vertebra. This keel extends in a plane which is non-perpendicular to the outer surface; and preferably there are two of the keels extending from the outer surface which are preferably offset laterally from one another. In another embodiment, an anterior shelf is provided at an anterior end of the outer surface, and this anterior shelf extends vertically away from the inner surface in order to help prevent bone growth from the adjacent vertebra towards the inner surface. Further in accordance with disclosed embodiments, various materials, shapes and forms of construction of the component and/or keel provide various benefits. | 08-26-2010 |
Tom Kaufmann, Ippenschied DE
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20100241314 | STEERING DEVICE FOR ADJUSTING A WHEEL STEERING ANGLE - A steering device for adjusting a wheel steering angle of a wheel of a motor vehicle is disclosed, which steering device has a wheel guide member and a steering control unit. The steering control unit includes a basic steering function and an actuator travel control system for adjusting travel of the wheel guide member on the basis of a steering angle setpoint value. | 09-23-2010 |
20130134967 | METHOD AND CIRCUIT ARRANGEMENT FOR CHECKING THE ROTOR POSITION OF A SYNCHROUNOUS MACHINE - A method for validating a vehicle-to-X message, in which the message is received by an antenna arrangement having a least two antenna elements connected with a communication device. An electromagnetic field strength of the message is recorded based on different reception characteristics with different power densities, wherein the message includes an absolute position of a transmitter, and an absolute position of a receiver determined on the basis of global satellite navigation or on a map comparison. A first relative position of the transmitter is calculated from the absolute positions of the receiver and the transmitter. A second relative position is calculated from the ratio of the power densities or read out from a reference diagram. If a comparison of the first and second relative positions reveals a large degree of correspondence, the message is validated, and if a large degree of deviation is detected, the message is rejected. | 05-30-2013 |
20130300324 | Method for Determining the Speed of a Synchronous Machine, Circuit Configuration for Actuating a Synchronous Machine, and Use of Such a Configuration - The invention relates to a method wherein the speed of the rotor of an electronically commutated synchronous machine is determined or controlled by means of one or more rotor position sensors, in particular, three rotor position sensors that are fixed to the stator, and a time measuring device, wherein the angle traveled by the rotor and the time lapsed during the travel are measured, wherein the measured angle traveled by the rotor is corrected by means of one or more first correction constants, in particular a differential for correcting for the influence of non-uniform positioning or expansion of the position marking of the rotor, and a circuit configuration for actuating an electronically commutated synchronous machine. | 11-14-2013 |
20130304345 | Method and Device for Controlling an Electrohydraulic Brake System - A system and device and a method for controlling an electrohydraulic brake system of a motor vehicle especially adapted for brake by wire applications. The embodiments carryout position control of an actuator of an electronically activatable pressure supply unit based on the actuator position actual value and on and actuator position reference value which is determined on the basis of a pressure reference value. | 11-14-2013 |
20140300299 | Method for Controlling an Electronically Commutated Polyphase DC Motor - A method for controlling a brushless DC motor (BLDC motor) having a rotor, a stator and an angle sensor and a logic circuit for generating the phase voltages of the windings depending on the phase angle of the rotor. The logic circuit access a lookup table, in which to implement commutation with block-shaped, trapezoidal, sinusoidal, sinoid-based signal waveforms. The drive values are stored for the electrical phase angle of the rotor for generating phase voltages (V | 10-09-2014 |