Patent application number | Description | Published |
20110066014 | METHOD AND APPARATUS FOR CEREBRAL OXIMETRY - The present invention pertains to a method and apparatus for cerebral oximetry. A modulated optical signal based on a digital code sequence is transmitted to the human brain. A temporal transfer characteristic is derived from the modulated optical signal. Oxygen level in the brain is determined based on the temporal transfer characteristic. | 03-17-2011 |
20110118572 | METHOD AND APPARATUS FOR TOTAL HEMOGLOBIN MEASUREMENT - The present invention pertains to a method and apparatus for total hemoglobin measurement. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Total hemoglobin is determined based on the temporal transfer characteristic. | 05-19-2011 |
20110118575 | METHOD AND APPARATUS FOR PRESSURE SORE DETECTION - The present invention pertains to a method and apparatus for pressure sore detection. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Tissue characteristics is determined based on the temporal transfer characteristic. | 05-19-2011 |
20120130257 | METHOD AND APPARATUS FOR TISSUE MEASUREMENT POSITION TRACKING AND DEPTH ADJUSTMENT - The present invention pertains to a method and apparatus for pressure sore detection. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Tissue characteristics is determined based on the temporal transfer characteristic. | 05-24-2012 |
20120203114 | INTRINSIC AND SWEPT-SOURCE RAMAN SPECTROSCOPY - The present invention pertains to a method and an apparatus for Raman spectroscopy of human tissue. Human tissue is illuminated with a laser emitting a first wavelength of light. A Raman signal is measured and optical properties are determined at this wavelength such that the measured Raman signal can be corrected based on determined optical properties. Determined optical properties may be the scattering coefficient and absorption coefficient of the tissue. A system for Raman spectroscopy of human tissue includes a frequency sweeping laser light source for illumination, and a filtered detector for collecting the Raman signal. | 08-09-2012 |
20130035569 | METHOD AND APPARATUS FOR HEMOMETRY - The present invention pertains to a method and apparatus for hemometry in humans. Pressure is applied proximal to a target area in human tissue. A modulated optical signal based on a digital code sequence is transmitted to the target area. A temporal transfer characteristic is derived from the modulated optical signal. Concentration of an analyte is determined based on the temporal transfer characteristic. | 02-07-2013 |
20130317331 | Monte Carlo and Iterative Methods for Determination of Tissue Oxygen Saturation - A method for determining oxygen saturation includes emitting light from sources into tissue; detecting the light by detectors subsequent to reflection; and generating reflectance data based on detecting the light. The method includes determining a first subset of simulated reflectance curves from a set of simulated reflectance curves stored in a tissue oximetry device for a coarse grid; and fitting the reflectance data points to the first subset of simulated reflectance curves to determine a closest fitting one of the simulated reflectance curves. The method includes determining a second subset of simulated reflectance curves for a fine grid based on the closest fitting one of the simulated reflectance curves; determining a peak of absorption and reflection coefficients from the fine grid; and determining an absorption and a reflectance coefficient for the reflectance data points by performing a weighted average of the absorption coefficients and reflection coefficients from the peak. | 11-28-2013 |
20130324816 | Robust Calibration and Self-Correction for Tissue Oximetry Probe - A method for calibrating detectors of a self-contained, tissue oximetry device includes emitting light from a light source into a tissue phantom, detecting in a plurality of detectors the light emitted from the light source, subsequent to reflection from the tissue phantom, and generating a set of detector responses by the plurality of detectors based on detecting the light emitted from the light source. The method further includes determining a set of differences between the set of detector responses and a reflectance curve for the tissue phantom, and generating a set of calibration functions based on the set of differences. Each calibration function in the set of calibration functions is associated with a unique, light source-detector pair. The method further includes storing the set of calibration function in a memory of the self-contained, tissue oximetry device. | 12-05-2013 |
20130338458 | METHOD AND APPARATUS FOR TOTAL HEMOGLOBIN MEASUREMENT - The present invention pertains to a method and apparatus for total hemoglobin measurement. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is determined from the modulated optical signal. Total hemoglobin is determined based on the temporal transfer characteristic. | 12-19-2013 |
20140046152 | Wireless, Handheld, Tissue Oximetry Device - A system includes an enclosure having a processor and a memory coupled to the processor. The enclosure includes a display coupled to the processor where the display is visible from an exterior of the enclosure; and a battery within the enclosure coupled to the processor and the display. The enclosure includes a probe tip coupled to an exterior of the enclosure. The probe tip includes first, second, and third sensor openings. A first distance between the first and second sensor openings is different than a second distance between the first and third sensor openings. The enclosure includes code stored in the memory where the code is executable by the processor, and includes code to receive first data associated with the first and second sensor openings, code to receive second data associated with the first and second sensor openings, and code to perform SRS using the first and the second data. | 02-13-2014 |
20140148661 | Tissue Oximetry Probe Geometry for Robust Calibration and Self-Correction - A sensor head for a compact oximeter sensor device includes light sources and light detectors. A compact oximeter sensor device implementation is entirely self-contained, without any need to connect, via wires or wirelessly, to a separate system unit. The sources and detectors are arranged in a circular arrangement having various source-detector pair distances that allow for robust calibration and self-correction in a compact probe. Other source-detector arrangements are also possible. | 05-29-2014 |
20140148662 | Tissue Oximetry Probe with Tissue Marking Feature - An intraoperative tissue oximetry device includes a tissue marker that includes one or more pens or one or more similar ink sources, such that the tissue marker can mark tissue according to oxygen saturation measurements made by the tissue oximetry device, thereby visually delineating regions of potentially viable tissue from regions of potentially nonviable tissue. | 05-29-2014 |
20140155716 | Light Wavelength Selection for Avoidance of Surgical Dyes - A tissue oximetry device utilizes at least three or at least four different wavelengths of light for collection of reflectance data where the different wavelengths are longer than 730 nanometers. The three or four wavelengths are utilized to generate a range of reflectance data suited for accurate determination of oxygenated hemoglobin and deoxygenated hemoglobin concentrations. The relatively long wavelengths decrease optical interference from certain dyes, particularly methylene blue and PVPI, which may be present on tissue being analyzed for viability and further enhance the generation of accurate reflectance data. The wavelengths are 760 nanometers, 810 nanometers, and 850 nanometers, or 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers. | 06-05-2014 |
20140200486 | SYSTEM AND METHOD FOR CONTINUOUS MONITORING OF A HUMAN FOOT FOR SIGNS OF ULCER DEVELOPMENT - The present invention pertains to a system and method for monitoring a human foot by measuring pressures applied to regions of the foot or by measuring another tissue-health related condition. A light source in the 400 nm to 1400 nm range and a detector can be embedded in a wearable article that contacts tissue while in use, spaced 200 μm to 1 cm apart, and measure a tissue hemoglobin condition. A pressure-sensing array may be read by a low-power control circuit, and a power source can be incorporated in the article. An external processing unit wirelessly coupled to the control circuit can relate pressures measured with counts that are associated with injury risk, and an alert system can notify a patient if the counts exceed a predetermined threshold. A relationship between pressure experienced by a region of tissue and the risk of ulcer development in that region may be derived. | 07-17-2014 |
20140276775 | IDENTIFICATION OF SURGICAL SMOKE - A method includes assessing tumor margins and discriminating between tumor and non-tumor tissues by analyzing the compositional make-up of smoke produced during cautery resection of tissues. | 09-18-2014 |
20150055751 | METHOD AND APPARATUS FOR REDUCING X-RAY EXPOSURE - The present invention pertains to an apparatus and method for adaptive exposure in imaging systems. An x-ray source for producing x-ray radiation and an x-ray detector for measuring amount of x-ray radiation passing through the human patient and striking the detector can be used. A tomographic image of the human patient or a tomosynthetic image of the human patient can be generated. Region of interest filtering and equalization filtering can be utilized. Filtering can be accomplished with a mechanical shield or shutter or with electronic control of the x-ray source. | 02-26-2015 |