| Patent application number | Description | Published |
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| 20150051443 | DEVICES, SYSTEMS, AND METHODS FOR DEFORMING A BODY CHANNEL - Devices, system and methods for deforming body channels are disclosed herein. At least some embodiments described may be used to deform a body channel so as to decrease or prevent the normal intrachannel flow of material within the body channel. Such deformation may be used to treat such maladies as Gastroesophageal Reflux Disease. | 02-19-2015 |
| 20150065835 | IMPEDANCE DEVICES FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS - Impedance devices for obtaining conductance measurements within luminal organs. In at least one embodiment of an impedance device of the present disclosure, the device, comprises an elongated body and an detector positioned upon the elongated body, the detector comprising at least five electrodes and configured to obtain one or more conductance measurements generated using a first arrangement of four of the at least five electrodes and further configured to obtain one or more fluid velocity measurements using a second arrangement of four of the at least five electrodes when the elongated body is positioned within a fluid environment of a mammalian luminal organ, wherein the first arrangement is different from the second arrangement. | 03-05-2015 |
| 20150073329 | SYSTEMS, DEVICES, AND METHODS FOR AUTORETROPERFUSION - Devices, systems, and methods for autoretroperfusion. In at least one embodiment of a perfusion system of the present disclosure, the system comprises a first catheter having a proximal end, a distal end, and a first lumen therethrough, the distal end configured for insertion into a luminal organ of a patient, a coupler defining an outlet port and a first port, the coupler configured to engage the proximal end of the first catheter at the outlet port and to receive blood from a blood supply through the first port, a first tube having a proximal end, a distal end, and a lumen therethrough, the distal end of the first tube configured to engage the first port of the coupler and to receive the blood from the blood supply, and a first flow regulator in communication with one or more of the coupler and the first tube, the first flow regulator operable to regulate a flow and/or a pressure of the blood through at least part of the system, wherein the system is configured to permit the blood from the blood supply to flow through the first tube, the coupler, and the first catheter into the patient to treat a patient condition. | 03-12-2015 |
| 20150073533 | LINKED DEFLECTION DEVICES, SYSTEMS AND METHODS FOR THE PREVENTION OF STROKE - Devices, systems, and methods for the prevention of stroke. Devices and systems hereof comprise stents configured to fit within at least part of an artery extending from an aortic arch, and at least one component comprising parallel convex struts for diverting emboli from entering an artery when the component is positioned at or near its ostium. The stents and the deflection component(s) are coupled in a linked configuration. Additionally, a retrieval system is provided, the retrieval system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises an attachment portion configured to engage a device positioned within an artery extending from the aortic arch. | 03-12-2015 |
| 20150080805 | DEVICES AND SYSTEMS FOR ACCESSING CARDIAC TISSUE - Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces. | 03-19-2015 |
| 20150126837 | DEVICES, SYSTEMS, AND METHODS TO DETERMINE VOLUME REFLUX - Devices, systems, and methods to determine volume reflux. In an exemplary embodiment of a device of the present disclosure, the device comprises an elongated body having a sufficient length so that a distal end of the elongated body can extend to a gastroesophageal junction of a person while a proximal end of the device, or a connector coupled thereto, is present at or distal to a throat of the person relative to the gastroesophageal junction, and a plurality of least ten electrodes positioned at known distances from one another along the elongated body, wherein two or more of the plurality of electrodes can excite an electric field, detect within the electric field, or excite and detect within the electric field, wherein the device is configured to obtain gastric/reflux bolus data at or near the gastroesophageal junction. | 05-07-2015 |
| 20150126853 | ARTERIAL SYSTEM NAVIGATION METHODS AND DEVICES AND SYSTEMS TO PERFORM THE SAME - Arterial system navigation methods and devices and systems to perform the same. In an exemplary embodiment of a method of the present disclosure, the method comprises the steps of inserting at least part of an impedance device into an artery of a patient, the artery selected from the group consisting of a femoral artery and a radial artery, obtaining at least one conductance measurement while navigating a distal end of the impedance device through an arterial vasculature of the patient until the distal end is at or near a left ventricle, and performing at least one medical procedure at a location within the arterial vasculature. | 05-07-2015 |
| 20150141863 | DEVICES AND SYSTEMS FOR OBTAINING IMPEDANCE DATA - Devices and systems to measure luminal organ parameters using impedance. In at least one embodiment of an impedance device of the present disclosure, the impedance device comprises an elongated body having a distal body end and a pair of detection electrodes positioned in between a pair of excitation electrodes located at or near the distal body end, the pair of detection electrodes configured to obtain one or more conductance values within a mammalian luminal organ within a field generated by the pair of excitation electrodes, wherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the device and a known distance between the pair of detection electrodes. | 05-21-2015 |
| 20150142094 | DEFLECTION DEVICES, SYSTEMS AND METHODS FOR THE PREVENTION OF STROKE - Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch. | 05-21-2015 |
| 20150150559 | DEVICES, SYSTEMS, AND METHODS FOR DIAGNOSING AND DELIVERING THERAPEUTIC INTERVENTIONS IN THE PERITONEAL CAVITY - A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion. | 06-04-2015 |
| 20150173795 | DEVICES, SYSTEMS, AND METHODS FOR DELIVERING A SUBSTANCE WITHIN A MAMMALIAN LUMINAL ORGAN OR AREA ADJACENT THERETO - Devices, systems, and methods for delivering a substance within a mammalian luminal organ or area adjacent thereto. In at least one exemplary embodiment of a system of the present disclosure, the system comprises an inner delivery device, comprising an inner portion configured to receive a substance therein, a pock tip at or near a distal end of the inner delivery device, the pock tip configured to deliver the substance from the inner portion, through a pock tip aperture defined within the pock tip, and into a mammalian tissue and/or luminal organ, and an embolus positioned within the inner portion, the embolus configured so that the substance remains distal to the embolus when the substance is positioned within the inner portion. | 06-25-2015 |
| 20150190254 | RETROPERFUSION SYSTEMS, DEVICES, AND METHODS - Devices, systems, and methods for providing retroperfusion to at least one ischemic tissue in a minimally invasive manner are disclosed. At least some of the embodiments disclosed herein enable an anastomosis to be formed between a vein and an artery without the use of sutures and through a non-invasive procedure. In addition, various disclosed embodiments provide a cannula device comprising a Y-configuration for bifurcating arterial flow between an anastomosis and the underlying artery. The devices, systems and methods herein can further provide simultaneous autoretroperfusion therapy to more than one area of an ischemic tissue. | 07-09-2015 |
| 20150204856 | METHODS TO DETERMINE FLUID FILTRATION RATES THROUGH MAMMALIAN LUMINAL ORGANS - Methods to determine fluid filtration rates through mammalian luminal organs. In one method, the method comprises the steps of positioning a segment of a mammalian luminal organ within a device, the device configured to prevent axial flow conditions through a lumen of the segment from a first end of the segment to an opposite second end of the segment, obtaining a first segment measurement at a first time, obtaining a second segment measurement at a second time, and determining a rate of fluid filtration through a wall of the segment based upon a difference between the first segment measurement and the second segment measurement and a difference in time between the first time and the second time. | 07-23-2015 |
| 20150231374 | INTRAVASCULAR CATHETERS, SYSTEMS, AND METHODS - Devices, systems, and methods for lead delivery. In at least one exemplary embodiment of a catheter for delivering a lead within a mammalian body of the present disclosure, the catheter comprises an elongated tube comprising a wall extending from a proximal end to a distal end, a lead delivery channel within the elongated tube, the lead delivery channel defining an outlet for delivering a lead, a balloon chamber positioned at or near the distal end of the elongated tube, and at least one balloon positioned within the balloon chamber, the at least one balloon capable of inflation to reversibly anchor the elongated tube within a mammalian body when at least a portion of the elongated tube is positioned therein. | 08-20-2015 |
| 20150233941 | SUBSTANCES, VACCINES AND METHODS FOR DIAGNOSING AND REDUCING INCIDENCES OF TRANSPLANT REJECTION - Methods and products for diagnosing, treating and/or delaying onset of chronic allograft rejection, including cardiac allograft vasculopathy. The method for screening an allograft recipient (including pregnant women) for chronic allograft rejection comprises the steps of measuring an amount of a natural antibody within a biological sample and comparing the amount of the first natural antibody with the amount of the first natural antibody present within a control sample; wherein a decrease in the amount of the first natural antibody as compared to those levels seen in the control indicates a diagnosis of being at-risk for or experiencing chronic allograft rejection. Furthermore, in an embodiment of a composition for preventing or treating chronic allograft rejection, the composition comprises a therapeutically effective amount of phosphorylcholine sufficient to initiate the production of anti-phoshporylecholine natural antibodies in a mammal following administration thereto. | 08-20-2015 |
| 20150265284 | ENDOGRAFT DEVICES AND METHODS TO USE THE SAME - Various endograft assemblies and methods for using the same. In at least one embodiment of an endograft assembly of the present disclosure, the endograft assembly comprises an endograft and a tube defining one or more tube openings coupled to said endograft. In another embodiment of an endograft assembly of the present disclosure, the endograft assembly comprises an endograft, a sponge sheath coupled to the endograft, and a reservoir bag coupled to the sponge sheath, said reservoir bag capable of receiving fluid from the sponge sheath. | 09-24-2015 |
| 20150297110 | DEVICES, SYSTEMS, AND METHODS FOR DETERMINING VEIN GEOMETRIC AND COMPLIANCE PROFILES FOR VENOUS STENTING - Devices, systems, and methods for determining vein geometric and compliance profiles for venous stenting. In one device embodiment, the device comprises an elongated body configured to fit within a mammalian luminal organ, a balloon coupled to the elongated body capable of and configured for inflation and deflation within the mammalian luminal organ, at least two excitation electrodes positioned along the elongated body within the balloon, and a plurality of at least three detection electrodes positioned in between at least two of the at least two excitation electrodes, wherein a first pair of two adjacent detection electrodes of the at least three detection electrodes can detect an electric field generated by the at least two excitation electrodes and obtain a first conductance measurement within the balloon, and a second pair of two adjacent detection electrodes can detect the electric field and obtain a second conductance measurement within the balloon. | 10-22-2015 |
| 20150297111 | METHODS FOR GENERATING LUMINAL ORGAN PROFILES USING IMPEDANCE - Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site. | 10-22-2015 |
| 20150297112 | SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES - Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements. | 10-22-2015 |
| 20150297113 | Devices and Systems for Navigation and Positioning a Central Venous Catheter Within a Patient - Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet. | 10-22-2015 |
| 20150328030 | GASTRIC DEVICES, SYSTEMS, AND METHODS - Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component. | 11-19-2015 |
| 20150352338 | DEVICES, SYSTEMS, AND METHODS FOR AUTO-RETROPERFUSION OF THE CEREBRAL VENOUS SYSTEM - Devices, systems, and methods for auto-retroperfusion of the cerebral venous system. In an exemplary embodiment of a catheter for controlling blood perfusion pressure of the present disclosure, the catheter comprises a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen and adapted to move between an expanded configuration and a deflated configuration, and at least one sensor coupled with the distal end of the body, each of the at least one sensors adapted to gather data relating to a fluid flowing through the lumen, wherein the catheter is configured to be coupled to a flow unit for regulating the flow and pressure of a fluid. | 12-10-2015 |
| 20150366485 | DEVICES AND METHODS FOR SIZING VALVE APERTURES AND LUMINAL ORGANS - Devices and methods for sizing valve apertures and luminal organs. In at least one embodiment of a device for obtaining measurements within a luminal organ of the present disclosure, the device comprises an elongated body, and at least one sizing finger positioned at a distal end of the elongated body, the at least one sizing finger configured to move from a first position to a second position by way of adjustment of at least one movable device coupled thereto, wherein a dimensional measurement within the luminal organ can be determined based upon the first position and the second position. | 12-24-2015 |
| 20160000568 | DEVICES AND METHODS FOR CONTROLLING BLOOD PERFUSION PRESSURE - Devices and methods for controlling blood perfusion pressure. In an exemplary device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel, wherein the partial occluder is configured to equalize the first blood pressure at the first area with the second blood pressure at the second area. | 01-07-2016 |
| 20160022273 | DEVICES, SYSTEMS, AND METHODS FOR INVERTING AND CLOSING THE LEFT ATRIAL APPENDAGE - Devices, systems, and methods are disclosed for inverting and closing a left atrial appendage. Certain methods include the steps of inverting a distal portion of a left atrial appendage and constraining the inverted portion using at least a snare device configured to be fit around the inverted portion of the left atrial appendage and closed, so that the inverted portion is securely circumscribed and closed. Devices and systems related to such methods are also described and include a catheter system comprising a vacuum tube and a snare slidably disposed within a catheter. | 01-28-2016 |
| 20160067031 | METHODS AND USES OF MEDIASTINAL PLEURA TISSUE FOR VARIOUS STENT AND OTHER MEDICAL APPLICATIONS - Methods, products and uses of or relating to biological tissues for various stent and other medical applications are disclosed. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a tissue comprising at least a portion of parietal pleura, selecting a sample of mediastinal pleura tissue from the parietal pleura tissue, and fixing the sample of mediastinal pleura tissue using a fixative, resulting in a fixed sample. Furthermore, in an embodiment of a tissue product of the present disclosure, the tissue product comprises a frame configured to retain mediastinal pleura tissue thereon and such tissue coupled to the frame. | 03-10-2016 |
| 20160067449 | Apparatus and Methods Relating to Intravascular Positioning of Distal End of Catheter - Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet. In another embodiment, techniques for identifying and locating obstructions in the vessel in which a device is disposed are disclosed. | 03-10-2016 |
| 20160081695 | SEPTAL OCCLUSION DEVICES AND METHODS - A magnetic device and method are disclosed for providing a safer and more reliable technique for closing a hole or rupture in the septum of the heart. A device is disclosed with proximal and distal occluders that are connected to one another via a catheter and are inserted on either side of the hole or rupture. Also disclosed are two patches that are placed on either side of the hole or rupture with at least one of the patches being composed of magnetic material with the other being magnetic or metallic. | 03-24-2016 |
| 20160081735 | SYSTEMS AND METHODS FOR CRYOABLATION OF A TISSUE - Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber. | 03-24-2016 |
