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Kassab, US

Bobby Kassab, Spring Valley, CA US

Patent application numberDescriptionPublished
20160127291ANONYMOUS MOBILE GROUP COMMUNICATIONS - A text-notification application for iOS and Android devices that facilitates broadcasting group messages for any size group, for any purpose, without requiring users to disclose email or cell phone contact information. Users can configure their own group channels to send and receive messages anonymously.05-05-2016

Dorothy Kassab, Canastota, NY US

Patent application numberDescriptionPublished
20140106298Clinical Dispenser and Applicator - The present invention relates to a clinical dispenser and applicator and, more particularly, to a clinical dispenser and applicator that is structured to hold and dispense a micro amount (one to several drops) of liquids/solvents in a clinical setting.04-17-2014

Elias H. Kassab, Grosse Pointe Shores, MI US

Patent application numberDescriptionPublished
20130150874CATHETER SYSTEM WITH BALLOON-MOUNTED PLAQUE-MODIFYING ELEMENTS - A plaque-modifying balloon and method for use in an endovascular procedure includes an elongated balloon that defines a longitudinal axis and is inflatable from a first deflated configuration to a second radially expanded configuration. One or more plaque-modifying elements are mounted on the outside of the inflatable balloon. Optionally, a compressible sheath made of a relatively low durometer, flexible material is mounted on the balloon to cover the elements during transit of the plaque-modifying balloon to and from the treatment site.06-13-2013
20140058358DRUG ELUTING SCULPTING BALLOON - A plaque-modifying balloon and method for use in an endovascular procedure includes an elongated balloon that defines a longitudinal axis and is inflatable from a first deflated configuration to a second radially expanded configuration. One or more plaque-modifying elements are mounted on the outside of the inflatable balloon. Optionally, a compressible sheath made of a relatively low durometer, flexible material is mounted on the balloon to cover the elements during transit of the plaque-modifying balloon to and from the treatment site.02-27-2014

Elias Habib Kassab, Grosse Pointe Shores, MI US

Patent application numberDescriptionPublished
20100076405ENDOVASCULAR SHEATH WITH GRADABLE STIFFNESS DEVICE AND METHOD - An endovascular sheath apparatus 03-25-2010
20110071490SYSTEM AND PROCEDURE FOR PLACING A MEDICAL DEVICE PROXIMATE AN OSTIAL LESION USING A CATHETER ASSEMBLY - A catheter system and method 03-24-2011
20110251595ENDOVASCULAR CATHETER AND METHOD WITH HYDRAULIC BLADDER SYSTEM - A endovascular sheath system 10-13-2011

Ghassan Kassab, Zionsville, IN US

Patent application numberDescriptionPublished
20120316599THROMBUS REMOVAL SYSTEMS AND DEVICES AND METHODS OF USING THE SAME - Thrombus removal systems and devices and methods of using the same. In an exemplary embodiment of a thrombus removal system of the present disclosure, the thrombus removal system comprises an umbrella catheter comprising an umbrella catheter tube and an umbrella positioned at least partially within the umbrella catheter tube when in a compressed configuration and positioned external to the umbrella catheter tube when in a deployed configuration, and a balloon catheter configured to fit around at least part of the umbrella catheter, the balloon catheter comprising a balloon catheter tube and a balloon coupled thereto, the balloon capable of inflation within a lumen of a mammalian vessel to substantially or completely occlude the lumen of the mammalian vessel, wherein the thrombus removal system is configured to disrupt and/or dissolve and remove at least a portion of a thrombus positioned within the lumen of the mammalian vessel.12-13-2012
20130144324DEVICES, SYSTEMS AND METHODS FOR CONTROLLING LOCAL BLOOD PRESSURE - Devices, systems, and methods for controlling local blood pressure. In an exemplary embodiment of a device for exposing a blood vessel to increased pressure of the present disclosure, the device comprises an anchor configured for placement into a blood vessel and to expand independently from a particle held from flowing away by the anchor, the particle configured to gradually expand due to exposure to blood flow.06-06-2013
20150039079DEVICES AND METHODS FOR ASSISTING VALVE FUNCTION, REPLACING VENOUS VALVES, AND PREDICTING VALVE TREATMENT SUCCESS - Devices and methods for assisting valve function, replacing venous valves, and predicting valve treatment successes. In at least one exemplary embodiment of an endograft body configured for expansion within a luminal organ of the present disclosure, the endograft body comprises (a) a first portion having a proximal end defining a proximal end aperture and a distal end defining a distal end aperture, the first portion configured to increase a velocity of fluid flowing therethrough, (b) a second portion having a second portion proximal end defining a second portion proximal end aperture and a second portion distal end defining a second portion distal end aperture.02-05-2015
20150230947Tricuspid Regurgitation Model and Methods of Evaluating Intraluminal Medical Devices - Animal models useful in the evaluation of medical devices, such as intraluminal medical devices, including intraluminal valve prostheses, are described. An example animal model comprises an animal in which a chordae tendineae attached to at least one of the leaflets of the tricuspid valve has been cut during an interventional procedure. Methods of evaluating intraluminal medical devices are also described. An example methods comprises cutting chordae tendineae attached to a leaflet of a tricuspid valve of an animal; allowing the animal to recover from the step of cutting the chordae tendineae; implanting an intraluminal medical device at a target site within a body vessel of the animal; allowing the animal to recover from the step of implanting an intraluminal medical device; and monitoring in vivo performance of the intraluminal medical device.08-20-2015

Patent applications by Ghassan Kassab, Zionsville, IN US

Ghassan S. Kassab, Newport Coast, CA US

Patent application numberDescriptionPublished
20090023176Devices, systems and methods for isometric and isotonic contraction of blood vessels using an isovolumetric myograph - The present invention discloses devices, systems and methods for the isovolumic measurement of vasoactivity in a blood vessel (01-22-2009
20090118637METHODS FOR MEASURING CROSS-SECTIONAL AREAS AND PRESSURE GRADIENTS IN LUMINAL ORGANS - The present disclosure comprises a system, catheter and method for measuring the cross-sectional areas and pressure gradients in any hollow organ, such as, for example, blood vessels. One embodiment of such a method includes the steps of introducing an impedance catheter into a treatment site, providing electrical current flow to the treatment site, injecting a first solution and measuring a first conductance value, injecting a second solution and measuring a second conductance value, and calculating the cross-sectional area of the treatment site, in part, based on the first and second conductance values.05-07-2009
20090306770Tissue engineering of blood vessels - Method and apparatus for mapping the shape and dimensions of a 3-dimensional body, by applying to the 3-dimensional body a stretchable covering configured and dimensioned such that in its stretched condition it tightly engages and conforms to the shape and dimensions of the 3-dimensional body to be mapped. The stretchable covering carries a plurality of reference devices, such as bands and/or markers which are at known or determinable reference locations in an initial condition of the covering, and which change their locations in the stretched condition of the stretchable covering according to the shape and dimensions of the 3-dimensional body covered thereby. The locations of the markers on the stretchable covering are determined after the stretchable covering has been applied to the 3-dimensional body, and are utilized to produce a map of the shape and dimensions of the 3-dimensional body.12-10-2009
20110034824PLAQUE TYPE DETERMINATION DEVICES, SYSTEMS, AND METHODS - Plaque type determination devices, systems, and methods. In at least one exemplary embodiment of a device for assessing composition of a plaque of the present disclosure, the device comprises an elongate body having a longitudinal axis and a distal end, a first excitation electrode and a second excitation electrode located along the longitudinal axis of the body near the distal end of the elongate body, and a first detection electrode and a second detection electrode along the longitudinal axis of the body and in between the first and second excitation electrodes, wherein when a current source in communication with at least one of the first excitation electrode and the second excitation electrode applies current thereto to facilitate measurement of two or more conductance values within a vessel containing at least part of the elongate body at or near a plaque site, a plaque type determination can be made based upon a calculation of tissue conductance using at least one of the two or more conductance values.02-10-2011
20120143078DEVICES AND SYSTEMS TO MEASURE LUMINAL ORGAN PARAMETERS USING IMPEDANCE - Devices and systems to measure luminal organ parameters using impedance. In at least one embodiment of an impedance device of the present disclosure, the impedance device comprises an elongated body having a distal body end and a pair of detection electrodes positioned in between a pair of excitation electrodes located at or near the distal body end, the pair of detection electrodes configured to obtain one or more conductance values within a mammalian luminal organ within a field generated by the pair of excitation electrodes, wherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the device and a known distance between the pair of detection electrodes.06-07-2012

Patent applications by Ghassan S. Kassab, Newport Coast, CA US

Ghassan S. Kassab, San Diego, CA US

Patent application numberDescriptionPublished
20140330306DEVICES AND SYSTEMS FOR INVERTING AND CLOSING THE LEFT ATRIAL APPENDAGE - Devices, systems, and methods for inverting and closing the left atrial appendage. In at least one embodiment of a method for closing a left atrial appendage of the present disclosure, the method comprises the steps of inverting a distal portion of a left atrial appendage, and constraining the inverted distal portion of the left atrial appendage using a device configured to fit within an interior of the left atrial appendage.11-06-2014
20150064140METHODS AND USES OF BIOLOGICAL TISSUES FOR VARIOUS STENT AND OTHER MEDICAL APPLICATIONS - Methods and uses of biological tissues for various stent and other medical applications. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a mammalian tissue comprising at least a portion of a pulmonary region tissue, selecting a sample of pulmonary region tissue from the at least a portion of a pulmonary region tissue, and fixing the sample of pulmonary region tissue using a fixative, resulting in a fixed sample. In at least one embodiment, the step of selecting a sample of pulmonary region tissue comprises selecting a sample of pulmonary ligament tissue from the mammalian tissue.03-05-2015

Ghassan S. Kassab, La Jolla, CA US

Patent application numberDescriptionPublished
20150051443DEVICES, SYSTEMS, AND METHODS FOR DEFORMING A BODY CHANNEL - Devices, system and methods for deforming body channels are disclosed herein. At least some embodiments described may be used to deform a body channel so as to decrease or prevent the normal intrachannel flow of material within the body channel. Such deformation may be used to treat such maladies as Gastroesophageal Reflux Disease.02-19-2015
20150065835IMPEDANCE DEVICES FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS - Impedance devices for obtaining conductance measurements within luminal organs. In at least one embodiment of an impedance device of the present disclosure, the device, comprises an elongated body and an detector positioned upon the elongated body, the detector comprising at least five electrodes and configured to obtain one or more conductance measurements generated using a first arrangement of four of the at least five electrodes and further configured to obtain one or more fluid velocity measurements using a second arrangement of four of the at least five electrodes when the elongated body is positioned within a fluid environment of a mammalian luminal organ, wherein the first arrangement is different from the second arrangement.03-05-2015
20150073329SYSTEMS, DEVICES, AND METHODS FOR AUTORETROPERFUSION - Devices, systems, and methods for autoretroperfusion. In at least one embodiment of a perfusion system of the present disclosure, the system comprises a first catheter having a proximal end, a distal end, and a first lumen therethrough, the distal end configured for insertion into a luminal organ of a patient, a coupler defining an outlet port and a first port, the coupler configured to engage the proximal end of the first catheter at the outlet port and to receive blood from a blood supply through the first port, a first tube having a proximal end, a distal end, and a lumen therethrough, the distal end of the first tube configured to engage the first port of the coupler and to receive the blood from the blood supply, and a first flow regulator in communication with one or more of the coupler and the first tube, the first flow regulator operable to regulate a flow and/or a pressure of the blood through at least part of the system, wherein the system is configured to permit the blood from the blood supply to flow through the first tube, the coupler, and the first catheter into the patient to treat a patient condition.03-12-2015
20150073533LINKED DEFLECTION DEVICES, SYSTEMS AND METHODS FOR THE PREVENTION OF STROKE - Devices, systems, and methods for the prevention of stroke. Devices and systems hereof comprise stents configured to fit within at least part of an artery extending from an aortic arch, and at least one component comprising parallel convex struts for diverting emboli from entering an artery when the component is positioned at or near its ostium. The stents and the deflection component(s) are coupled in a linked configuration. Additionally, a retrieval system is provided, the retrieval system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises an attachment portion configured to engage a device positioned within an artery extending from the aortic arch.03-12-2015
20150080805DEVICES AND SYSTEMS FOR ACCESSING CARDIAC TISSUE - Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.03-19-2015
20150126837DEVICES, SYSTEMS, AND METHODS TO DETERMINE VOLUME REFLUX - Devices, systems, and methods to determine volume reflux. In an exemplary embodiment of a device of the present disclosure, the device comprises an elongated body having a sufficient length so that a distal end of the elongated body can extend to a gastroesophageal junction of a person while a proximal end of the device, or a connector coupled thereto, is present at or distal to a throat of the person relative to the gastroesophageal junction, and a plurality of least ten electrodes positioned at known distances from one another along the elongated body, wherein two or more of the plurality of electrodes can excite an electric field, detect within the electric field, or excite and detect within the electric field, wherein the device is configured to obtain gastric/reflux bolus data at or near the gastroesophageal junction.05-07-2015
20150126853ARTERIAL SYSTEM NAVIGATION METHODS AND DEVICES AND SYSTEMS TO PERFORM THE SAME - Arterial system navigation methods and devices and systems to perform the same. In an exemplary embodiment of a method of the present disclosure, the method comprises the steps of inserting at least part of an impedance device into an artery of a patient, the artery selected from the group consisting of a femoral artery and a radial artery, obtaining at least one conductance measurement while navigating a distal end of the impedance device through an arterial vasculature of the patient until the distal end is at or near a left ventricle, and performing at least one medical procedure at a location within the arterial vasculature.05-07-2015
20150141863DEVICES AND SYSTEMS FOR OBTAINING IMPEDANCE DATA - Devices and systems to measure luminal organ parameters using impedance. In at least one embodiment of an impedance device of the present disclosure, the impedance device comprises an elongated body having a distal body end and a pair of detection electrodes positioned in between a pair of excitation electrodes located at or near the distal body end, the pair of detection electrodes configured to obtain one or more conductance values within a mammalian luminal organ within a field generated by the pair of excitation electrodes, wherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the device and a known distance between the pair of detection electrodes.05-21-2015
20150142094DEFLECTION DEVICES, SYSTEMS AND METHODS FOR THE PREVENTION OF STROKE - Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.05-21-2015
20150150559DEVICES, SYSTEMS, AND METHODS FOR DIAGNOSING AND DELIVERING THERAPEUTIC INTERVENTIONS IN THE PERITONEAL CAVITY - A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion.06-04-2015
20150173795DEVICES, SYSTEMS, AND METHODS FOR DELIVERING A SUBSTANCE WITHIN A MAMMALIAN LUMINAL ORGAN OR AREA ADJACENT THERETO - Devices, systems, and methods for delivering a substance within a mammalian luminal organ or area adjacent thereto. In at least one exemplary embodiment of a system of the present disclosure, the system comprises an inner delivery device, comprising an inner portion configured to receive a substance therein, a pock tip at or near a distal end of the inner delivery device, the pock tip configured to deliver the substance from the inner portion, through a pock tip aperture defined within the pock tip, and into a mammalian tissue and/or luminal organ, and an embolus positioned within the inner portion, the embolus configured so that the substance remains distal to the embolus when the substance is positioned within the inner portion.06-25-2015
20150190254RETROPERFUSION SYSTEMS, DEVICES, AND METHODS - Devices, systems, and methods for providing retroperfusion to at least one ischemic tissue in a minimally invasive manner are disclosed. At least some of the embodiments disclosed herein enable an anastomosis to be formed between a vein and an artery without the use of sutures and through a non-invasive procedure. In addition, various disclosed embodiments provide a cannula device comprising a Y-configuration for bifurcating arterial flow between an anastomosis and the underlying artery. The devices, systems and methods herein can further provide simultaneous autoretroperfusion therapy to more than one area of an ischemic tissue.07-09-2015
20150204856METHODS TO DETERMINE FLUID FILTRATION RATES THROUGH MAMMALIAN LUMINAL ORGANS - Methods to determine fluid filtration rates through mammalian luminal organs. In one method, the method comprises the steps of positioning a segment of a mammalian luminal organ within a device, the device configured to prevent axial flow conditions through a lumen of the segment from a first end of the segment to an opposite second end of the segment, obtaining a first segment measurement at a first time, obtaining a second segment measurement at a second time, and determining a rate of fluid filtration through a wall of the segment based upon a difference between the first segment measurement and the second segment measurement and a difference in time between the first time and the second time.07-23-2015
20150231374INTRAVASCULAR CATHETERS, SYSTEMS, AND METHODS - Devices, systems, and methods for lead delivery. In at least one exemplary embodiment of a catheter for delivering a lead within a mammalian body of the present disclosure, the catheter comprises an elongated tube comprising a wall extending from a proximal end to a distal end, a lead delivery channel within the elongated tube, the lead delivery channel defining an outlet for delivering a lead, a balloon chamber positioned at or near the distal end of the elongated tube, and at least one balloon positioned within the balloon chamber, the at least one balloon capable of inflation to reversibly anchor the elongated tube within a mammalian body when at least a portion of the elongated tube is positioned therein.08-20-2015
20150233941SUBSTANCES, VACCINES AND METHODS FOR DIAGNOSING AND REDUCING INCIDENCES OF TRANSPLANT REJECTION - Methods and products for diagnosing, treating and/or delaying onset of chronic allograft rejection, including cardiac allograft vasculopathy. The method for screening an allograft recipient (including pregnant women) for chronic allograft rejection comprises the steps of measuring an amount of a natural antibody within a biological sample and comparing the amount of the first natural antibody with the amount of the first natural antibody present within a control sample; wherein a decrease in the amount of the first natural antibody as compared to those levels seen in the control indicates a diagnosis of being at-risk for or experiencing chronic allograft rejection. Furthermore, in an embodiment of a composition for preventing or treating chronic allograft rejection, the composition comprises a therapeutically effective amount of phosphorylcholine sufficient to initiate the production of anti-phoshporylecholine natural antibodies in a mammal following administration thereto.08-20-2015
20150265284ENDOGRAFT DEVICES AND METHODS TO USE THE SAME - Various endograft assemblies and methods for using the same. In at least one embodiment of an endograft assembly of the present disclosure, the endograft assembly comprises an endograft and a tube defining one or more tube openings coupled to said endograft. In another embodiment of an endograft assembly of the present disclosure, the endograft assembly comprises an endograft, a sponge sheath coupled to the endograft, and a reservoir bag coupled to the sponge sheath, said reservoir bag capable of receiving fluid from the sponge sheath.09-24-2015
20150297110DEVICES, SYSTEMS, AND METHODS FOR DETERMINING VEIN GEOMETRIC AND COMPLIANCE PROFILES FOR VENOUS STENTING - Devices, systems, and methods for determining vein geometric and compliance profiles for venous stenting. In one device embodiment, the device comprises an elongated body configured to fit within a mammalian luminal organ, a balloon coupled to the elongated body capable of and configured for inflation and deflation within the mammalian luminal organ, at least two excitation electrodes positioned along the elongated body within the balloon, and a plurality of at least three detection electrodes positioned in between at least two of the at least two excitation electrodes, wherein a first pair of two adjacent detection electrodes of the at least three detection electrodes can detect an electric field generated by the at least two excitation electrodes and obtain a first conductance measurement within the balloon, and a second pair of two adjacent detection electrodes can detect the electric field and obtain a second conductance measurement within the balloon.10-22-2015
20150297111METHODS FOR GENERATING LUMINAL ORGAN PROFILES USING IMPEDANCE - Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site.10-22-2015
20150297112SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES - Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements.10-22-2015
20150297113Devices and Systems for Navigation and Positioning a Central Venous Catheter Within a Patient - Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet.10-22-2015
20150328030GASTRIC DEVICES, SYSTEMS, AND METHODS - Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.11-19-2015
20150352338DEVICES, SYSTEMS, AND METHODS FOR AUTO-RETROPERFUSION OF THE CEREBRAL VENOUS SYSTEM - Devices, systems, and methods for auto-retroperfusion of the cerebral venous system. In an exemplary embodiment of a catheter for controlling blood perfusion pressure of the present disclosure, the catheter comprises a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen and adapted to move between an expanded configuration and a deflated configuration, and at least one sensor coupled with the distal end of the body, each of the at least one sensors adapted to gather data relating to a fluid flowing through the lumen, wherein the catheter is configured to be coupled to a flow unit for regulating the flow and pressure of a fluid.12-10-2015
20150366485DEVICES AND METHODS FOR SIZING VALVE APERTURES AND LUMINAL ORGANS - Devices and methods for sizing valve apertures and luminal organs. In at least one embodiment of a device for obtaining measurements within a luminal organ of the present disclosure, the device comprises an elongated body, and at least one sizing finger positioned at a distal end of the elongated body, the at least one sizing finger configured to move from a first position to a second position by way of adjustment of at least one movable device coupled thereto, wherein a dimensional measurement within the luminal organ can be determined based upon the first position and the second position.12-24-2015
20160000568DEVICES AND METHODS FOR CONTROLLING BLOOD PERFUSION PRESSURE - Devices and methods for controlling blood perfusion pressure. In an exemplary device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel, wherein the partial occluder is configured to equalize the first blood pressure at the first area with the second blood pressure at the second area.01-07-2016
20160022273DEVICES, SYSTEMS, AND METHODS FOR INVERTING AND CLOSING THE LEFT ATRIAL APPENDAGE - Devices, systems, and methods are disclosed for inverting and closing a left atrial appendage. Certain methods include the steps of inverting a distal portion of a left atrial appendage and constraining the inverted portion using at least a snare device configured to be fit around the inverted portion of the left atrial appendage and closed, so that the inverted portion is securely circumscribed and closed. Devices and systems related to such methods are also described and include a catheter system comprising a vacuum tube and a snare slidably disposed within a catheter.01-28-2016
20160067031METHODS AND USES OF MEDIASTINAL PLEURA TISSUE FOR VARIOUS STENT AND OTHER MEDICAL APPLICATIONS - Methods, products and uses of or relating to biological tissues for various stent and other medical applications are disclosed. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a tissue comprising at least a portion of parietal pleura, selecting a sample of mediastinal pleura tissue from the parietal pleura tissue, and fixing the sample of mediastinal pleura tissue using a fixative, resulting in a fixed sample. Furthermore, in an embodiment of a tissue product of the present disclosure, the tissue product comprises a frame configured to retain mediastinal pleura tissue thereon and such tissue coupled to the frame.03-10-2016
20160067449Apparatus and Methods Relating to Intravascular Positioning of Distal End of Catheter - Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet. In another embodiment, techniques for identifying and locating obstructions in the vessel in which a device is disposed are disclosed.03-10-2016
20160081695SEPTAL OCCLUSION DEVICES AND METHODS - A magnetic device and method are disclosed for providing a safer and more reliable technique for closing a hole or rupture in the septum of the heart. A device is disclosed with proximal and distal occluders that are connected to one another via a catheter and are inserted on either side of the hole or rupture. Also disclosed are two patches that are placed on either side of the hole or rupture with at least one of the patches being composed of magnetic material with the other being magnetic or metallic.03-24-2016
20160081735SYSTEMS AND METHODS FOR CRYOABLATION OF A TISSUE - Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber.03-24-2016

Ghassan S. Kassab, Zionville, IN US

Patent application numberDescriptionPublished
20100030245MAGNETIC DEVICES FOR HIATAL HERNIA REMODELING - Devices and methods are disclosed for providing static and dynamic tissue and organ restriction. A magnetic component is used to stabilize an apparatus to provide tissue and organ restriction. Such a device is described with respect to occluding a hernia via a mesh attachment, and, alternatively, with respect to closing or reinforcing the crural closure via a parallel magnetic arrangement.02-04-2010

Ghassan S. Kassab, Zlonsville, IN US

Patent application numberDescriptionPublished
20100069849PERCUTANEOUS INTRAVASCULAR ACCESS TO CARDIAC TISSUE - Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.03-18-2010

Hisham Kassab, Rockville, MD US

Patent application numberDescriptionPublished
20100095220METHODS AND SYSTEMS FOR PROVIDING A MINI-WEBPAGE WITHIN A WEBPAGE - Methods and systems to enable an Intermediate Network Entity (INE) to modify a Web Page requested by an end-user. The modification may involve placing a Mini-Webpage designated areas of the requested Web Page. An INE may be enabled to receive a request for a Web Page, process the request, modify the requested Web Page by placing Mini-Webpages in designated areas of the Web Page. The methods would allow the Mini-Webpages to be formed by the INE, Web Page provider or a third party ad server. The Mini-Webpages may be targeted based on certain criteria such as the nature of the Web Page requested, the information about the end-user, and the information about the INE. An INE may share some of the economic benefits associated with the ability to convey desired information to an end-user.04-15-2010
20100228963METHODS OF PLACING ADVERTISMENTS, INTERSTITIALS AND TOOLBARS IN A WEB BROWSER - The present invention provides methods and systems that can render INE content to a web browser. Various methods and approaches are disclosed that when implemented would enable an INE to place some of INE's contents in a web browser of a user. The INE content can be in the form of a tool bar or interstitial content. The invention can provide one or more of the following advantages: a) provide an opportunity for INE to conduct e-commerce, b) enable an INE to develop alternate revenue generation model, and c) enable an INE or it's related entities to participate in e-commerce and advertising.09-09-2010

Mark A. Kassab US

Patent application numberDescriptionPublished
20110258504TEST ACCESS MECHANISM FOR DIAGNOSIS BASED ON PARTITIOINING SCAN CHAINS - Disclosed are representative embodiments of methods, apparatus, and systems for partitioning-based Test Access Mechanisms (TAM). Test response data are captured by scan cells of a plurality scan chains in a circuit under test and are compared with test response data expected for a good CUT to generate check values. Based on the check values, partition pass/fail signals are generated by partitioning scheme generators. Each of the partitioning scheme generators is configured to generate one of the partition pass/fail signals for one of partitioning schemes. A partitioning scheme divides the scan cells into a set of non-overlapping partitions. Based on the partition pass/fail signals, a failure diagnosis process may be performed.10-20-2011

Maroun Kassab, Essex Junction, VT US

Patent application numberDescriptionPublished
20110137602INSERTION OF FAULTS IN LOGIC MODEL USED IN SIMULATION - A method of selecting fault candidates based on the physical layout of an Integrated Circuit (IC) layout, that includes, identifying failing observation points in an IC layout, determining the failing observation points proximity geometry in the IC circuit layout, determining if a proximity criteria for the failing observation points is met, and identifying faults associated with the failing observation points that meet the proximity criteria; and including the identified faults in a fault candidate set.06-09-2011
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