Patent application number | Description | Published |
20110302151 | Query Execution Systems and Methods - System, method, and computer program product for processing data are disclosed. The method includes receiving a query for processing of data, wherein the data is stored in a table in a plurality of tables, wherein the table is stored on at least one node within the database system, determining an attribute of the table and another table in the plurality of tables, partitioning one of the table and the another table in the plurality of tables using the determined attribute into a plurality of partitions, and performing a join of at least two partitions of the table and the another table using the determined attribute. The join is performed on a single node in the database system. | 12-08-2011 |
20110302583 | SYSTEMS AND METHODS FOR PROCESSING DATA - A system, method, and computer program product for processing data are disclosed. The system includes a data processing framework configured to receive a data processing task for processing, a plurality of database systems coupled to the data processing framework, wherein the database systems are configured to perform a data processing task, and a storage component in communication with the data processing framework and the plurality database systems, configured to store information about each partition of the data processing task being processed by each database system and the data processing framework. The data processing task is configured to be partitioned into a plurality of partitions and each database system is configured to process a partition of the data processing task assigned for processing to that database system. Each database system is configured to perform processing of its assigned partition of the data processing task in parallel with another database system processing another partition of the data processing task assigned to the another database system. The data processing framework is configured to perform at least one partition of the data processing task. | 12-08-2011 |
Patent application number | Description | Published |
20150280287 | Battery, Integrated Circuit and Method of Manufacturing a Battery - A battery includes a first substrate having a first main surface, a second substrate made of a conducting material or semiconductor material, and a carrier of an insulating material. The carrier has a first and a second main surfaces, the second substrate being attached to the first main surface of the carrier. An opening is formed in the second main surface of the carrier to uncover a portion of a second main surface of the second substrate. The second main surface of the carrier is attached to the first substrate, thereby forming a cavity. The battery further includes an electrolyte disposed in the cavity. | 10-01-2015 |
20150280288 | Lithium Ion Battery, Integrated Circuit and Method of Manufacturing a Lithium Ion Battery - A lithium ion battery includes a first substrate having a first main surface, and a lid including an insulating material. The lid is attached to the first main surface of the first substrate, and a cavity is defined between the first substrate and the lid. The lithium ion battery further includes an electrical interconnection element in the lid, the electrical interconnection element providing an electrical connection between a first main surface and a second main surface of the lid. The lithium ion battery further includes an electrolyte in the cavity, an anode at the first substrate, the anode including a component made of a semiconductor material, and a cathode at the lid. | 10-01-2015 |
20150280289 | Lithium Ion Battery, Integrated Circuit and Method of Manufacturing a Lithium Ion Battery - A lithium ion battery includes a first substrate having a first main surface, and a lid including a conductive cover element, the lid being attached to the first main surface. A cavity is formed between the first substrate and the lid. The battery further includes an electrolyte disposed in the cavity. An anode of the battery includes a component made of a semiconductor material and is formed at the first substrate, and a cathode of the battery is formed at the lid. | 10-01-2015 |
Patent application number | Description | Published |
20100125068 | METHODS FOR INHIBITING PROTEIN KINASES - The present invention provides methods for inhibiting protein kinases selected from the group consisting of AKT, Checkpoint kinase, Aurora kinase, Pim kinases, and tyrosine kinase using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with protein kinases using such compounds. | 05-20-2010 |
20100143384 | NOVEL 4-CYANO, 4-AMINO, AND 4-AMINOMETHYL DERIVATIVES OF PYRAZOLO[1,5-a]PYRIDINES, PYRAZOLO[1,5-c]PYRIMIDINES AND 2H-INDAZOLE COMPOUNDS AND 5-CYANO, 5-AMINO, AND 5-AMINOMETHYL DERIVATIVES OF IMIDAZO[1,2-a]PYRIDINES, AND IMIDAZO[1,5-a]PYRAZINES AS CYCLIN DEPENDENT KINASE INHIBITORS - In its many embodiments, the present invention provides a novel class of 4-cyano, 4-amino, and 4-aminomethyl derivatives of pyrazolo[1,5-a]pyridine, pyrazolo[1,5-c]pyrimidine, and 2H-Indazole compounds and 5-cyano, 5-amino, and 5-aminomethyl derivatives of imidazo[1,2-a]pyridine and imidazo[1,5-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. | 06-10-2010 |
20110183933 | NOVEL MODULATORS OF CELL CYCLE CHECKPOINTS AND THEIR USE IN COMBINATION WITH CHECKPOINT KINASE INHIBITORS - In its many embodiments, the present invention provides a novel class of pyrimidine analogs of formula (V) as targeted mechanism-based modulators of cell cycle checkpoints. Cancers and/or malignancies can be treated by administration of a cell cycle checkpoint modulator of the invention. Also discussed are suitable combinations of the cell cycle checkpoint modulator with a checkpoint kinase inhibitor to produce synergistic apoptosis in cancer cells. The invention includes methods of treating cancers by administering the combination of the cell cycle checkpoint modulator and the checkpoint kinase inhibitor, pharmaceutical compositions comprising the activator as well as the combination and pharmaceutical kits. | 07-28-2011 |
20120029204 | SYNTHESIS OF SUBSTITUTED-3-AMINOPYRAZOLES - The present invention discloses a process of preparing compound of formula (I): wherein A, M, and Z are as defined herein. An example of a compound of formula (I) is 3-amino-1-methyl-1H-1′H-4,4′-bispyrazole. | 02-02-2012 |
Patent application number | Description | Published |
20100137326 | NOVEL 4-CYANO, 4-AMINO, AND 4-AMINOMETHYL DERIVATIVES OF PYRAZOLO[1,5-a]PYRIDINES, PYRAZOLO[1,5-c]PYRIMIDINES AND 2H-INDAZOLE COMPOUNDS AND 5-CYANO, 5-AMINO, AND 5-AMINOMETHYL DERIVATIVES OF IMIDAZO[1,2-a]PYRIDINES, AND IMIDAZO[1,5-a]PYRAZINES AS CYCLIN DEPENDENT KINASE INHIBITORS - In its many embodiments, the present invention provides a novel class of 4-cyano, 4-amino, and 4-aminomethyl derivatives of pyrazolo[1,5-a]pyridine, pyrazolo[1,5-c]pyrimidine, and 2H-Indazole compounds and 5-cyano, 5-amino, and 5-aminomethyl derivatives of imidazo[1,2-a]pyridine and imidazo[1,5-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. | 06-03-2010 |
Patent application number | Description | Published |
20120300134 | REMOTE CONTROL OPERABLE STANDS FOR TV DISPLAY - A rotary stand for TV screen or monitor, which require an adjustable angular position relative to its vertical axis, secured in a holder in a bearing column, mounted rotationally in a fixed mount, fitted with a controlled electric drive of the bearing column bi-directional rotation and a potentiometer for electric adjustment of the bearing column angular position is described together with a support stand that is mountable to a lateral wall. The stand has a programmable control system enabling the limit angular positions of the screen secured in the holder on the bearing column to be automatically set and programmed. A remote control for controlling the rotation of the TV monitor and an LED lighting strip for showing the position of the TV monitor selected and a direction of movement of the TV monitor are also provided. | 11-29-2012 |
20120325985 | ROTARY STAND FOR TV SCREEN OR MONITOR - A rotary stand for TV screen or monitor, which require an adjustable angular position relative to its vertical axis, secured in a holder in a bearing column, mounted rotationally in a fixed mount, fitted with a controlled electric drive of the bearing column bi-directional rotation and a potentiometer for electric adjustment of the bearing column angular position is described together with a support stand that is mountable to a lateral wall. A potentiometer directly coupled with the bearing surface, and a friction clutch, as a component of a kinematic drive chain, transfers torque from the electrical drive to the bearing column. The stand has a programmable control system enabling the limit angular positions of the screen secured in the holder on the bearing column to be automatically set and programmed. | 12-27-2012 |
20130088868 | LAMP WITH MULTIPLE COMBINED LIGHT REFLECTORS, LAMP CONNECTOR, AND PROXIMITY SENSOR FOR THE LAMP - Lighting systems and lighting assemblies are disclosed, including a lamp with several light sources positioned to produce a smoother more blended lighting effect. Three or more light sources may be included, and each source can be positioned in its own light well. The light wells can be conical in form but may have a side of a cone missing to connect it to adjacent light wells, including to both adjacent light wells. A proximity sensor may be included to turn on or off the lamp or to dim the lamp when a user's presence is detected. | 04-11-2013 |
Patent application number | Description | Published |
20090115417 | Three dimensional RF coil structures for field profiling - In one illustrative embodiment, a radio frequency (RF) coil is disclosed. The RF coil may include a plurality of transmission line elements, wherein at least one of the plurality of transmission line elements may have at least one dimension different than a dimension of another one of the plurality of transmission line elements. In some cases, each of the transmission line elements may include a signal line conductor and a ground plane conductor separated by a dielectric. | 05-07-2009 |
20110182920 | IDENTIFICATION OF A NOVEL CYSTEINE-RICH CELL PENETRATING PEPTIDE - The present invention relates to a nucleic acid molecule encoding a peptide capable of being internalized into a cell, wherein said nucleic acid molecule consists of (a) a nucleic acid molecule encoding a peptide having the amino acid sequence of SEQ ID NO: 2; (b) a nucleic acid molecule having the DNA sequence of SEQ ID NO: 1, wherein T is U if the nucleic acid molecule is RNA; or (d) a nucleic acid molecule encoding a peptide having at least 80% sequence identity with that of SEQ ID NO: 2, wherein at least at two positions selected from the group consisting of positions 1, 7 and 8 of SEQ ID NO: 2 a cysteine is present and wherein at least at four positions selected from the groups consisting of position 2, 4, 6, 9 or 10 of SEQ ID NO: 2 an arginine or a lysine is present. The present invention also relates to a peptide encoded by the nucleic acid of the invention, a fusion molecule comprising the peptide of the invention and a composition comprising the peptide or the fusion molecule of the invention. Furthermore, the present invention relates to a method of detecting the internalization behaviour of a fusion molecule of the invention, the composition of the invention for treating and/or preventing a condition selected from cancer, enzyme deficiency diseases, infarcts, cerebral ischemia, diabetes, inflammatory diseases, infections such as bacterial, viral or fungal infections, autoimmune diseases such as systemic lupus erythematodes (SLE) or rheumatoid arthritis, diseases with amyloid-like fibrils such as Alzheimer's disease (AD) and Parkinson's disease (PD) or certain forms of myopathy. | 07-28-2011 |
20120056620 | MULTIPLICATIVE INCREASE IN MRI DATA ACQUISITION WITH MULTI-BAND RF EXCITATION PULSES IN A SIMULTANEOUS IMAGE REFOCUSING PULSE SEQUENCE - Disclosed are methods and systems for carrying out super-multiplexed magnetic resonance imaging that entwines techniques previously used individually and independently of each other in Simultaneous Echo (of Imaging) Refocusing (SER or SIR) and Multi-Band (MB) excitation, in a single pulse sequence that provides a multiplication rather than summation of desirable effects while suppressing undesirable effects of each of the techniques that previously were used independently. | 03-08-2012 |
20130342200 | Method for Reducing Power Deposition in Magnetic Resonance Imaging Using Multiband Pulses and Multichannel Transmission - A method is provided for substantially simultaneously manipulating spins in a plurality of slice locations using a magnetic resonance imaging [“MRI”) system that includes a radio frequency (“RF”) coil array composed of a plurality of RF coil dements, and in which power deposition, which may be measured as specific absorption rate (“SAR”), is reduce A plurality of slice locations to be substantially simultaneously manipulated with the MRI system are selected, and an RF transmission map (B | 12-26-2013 |
20130342206 | Method for Rapid Whole Brain Magnetic Resonance Imaging with Contrast Preparation - A method for acquiring image data from a plurality of slice locations in a subject with a magnetic resonance imaging (MRI) system is provided. The method includes directing the MRI system to perform a pulse sequence that includes performing a contrast preparation module configured to generate contrast-encoded longitudinal magnetization and an image encoding module configured to acquire image data from multiple slice locations substantially simultaneously. The contrast preparation module generally includes tipping longitudinal magnetization into the transverse plane to produce transverse magnetization, generating contrast-prepared transverse magnetization by establishing an image contrast in the transverse magnetization, and tipping the contrast-prepared magnetization back along the longitudinal axis to produce the contrast-encoded longitudinal magnetization. | 12-26-2013 |
20140218026 | System and Method For Iteratively Calibrated Reconstruction Kernel For Accelerated Magnetic Resonance Imaging - A method for iteratively calibrating a reconstruction kernel for use in accelerated magnetic resonance imaging (MRI) is provided. An MRI system is used to acquire k-space data from multiple slice locations following the application of a multiband radio frequency (RF) excitation pulse. An initial reconstruction kernel is generated from the acquired k-space data, and this initial reconstruction kernel is used to produce an initial image for each of the multiple slice locations by applying the initial reconstruction kernel to the acquired k-space data. The average phase of each slice location is then calculated from these images, and used to shift the phase values of the subsequently acquired k-space data. From the phase-shifted k-space data, an updated reconstruction kernel is then generated. This process is repeated iteratively until a stopping criterion is satisfied. | 08-07-2014 |
20140253120 | SYSTEM AND METHOD FOR REDUCING RADIO FREQUENCY PEAK VOLTAGE AND POWER REQUIREMENTS IN MAGNETIC RESONANCE IMAGING USING TIME-SHIFTED MULTIBAND RADIO FREQUENCY PULSES - A system and method for producing images depicting a plurality of slice locations in a subject using a magnetic resonance imaging (“MRI”} system is provided. In particular, the system and method utilize time-shifted multiband radio frequency (“RF”} pulses to lower peak voltage and peak power requirements when using conventional multiband RF pulses. A time-shifted multiband RF pulse includes at least two component RF pulses, which may be single-band or multiband pulses. The component RF pulses are designed such that they do not have temporal footprints that completely overlap; although, they may have temporal foot-prints that partially overlap or do not overlap at all. The MRI system is used to acquire magnetic resonance signals formed in response to a time-shifted multiband RF pulse and, from these acquired signals, images depicting each of the plurality of slice locations in the subject are reconstructed. | 09-11-2014 |
20150115958 | Multiband Slice Accelerated Imaging With Balanced Slice-Selective Gradients - A computer-implemented method for performing multi-band slice accelerated imaging includes performing a low-resolution fast multi-dimensional reference scan to obtain a coil sensitivity map. A multiband imaging scan is performed to acquire a plurality of k-space lines representative of an anatomical area of interest. A multi-band signal corresponding to the plurality of k-space lines is separated into a plurality of image slices using a parallel imaging reconstruction technique and the coil sensitivity map. | 04-30-2015 |
20150309142 | Apparatus And Method For Multi-Band MR Imaging - A magnetic resonance method and system are provided for providing improved multi-band (MB) magnetic resonance imaging. The adaptive MB imaging can be achieved by providing one or more modified multi-band excitation pulse sequences that include at least either one nullified “dummy” slice within a slab that is not excited simultaneously with the other slices during a single multislice acquisition sequence, or one excitation slice group that utilizes a non-uniform slice spacing between simultaneously excited slices. Adaptive GRAPPA or slice-GRAPPA kernel sizes can also be used during image reconstruction to improve speed without excessive point spread blurring or MB reconstruction failure. A total leakage factor (TLF) can also be determined based on test images using modified MB excitation sequences, and used to improve the adaptive MB procedure. | 10-29-2015 |
20150309147 | Systems and Methods For Designing Magnetic Resonance Imaging Radio Frequency Pulses That Are Robust Against Physiological Motion Errors - Systems and methods for designing and/or using radio frequency (“RF”) pulses for in-vivo MRI applications, where the RF pulses are robust against errors due to physiological motion of organs during the respiratory cycle. For example, RF pulses are designed based on multi-channel B1+ maps correlated to different positions of the respiratory cycle. | 10-29-2015 |
20150362574 | MULTIBAND RF/MRI PULSE DESIGN FOR MULTICHANNEL TRANSMITTER - A method for designing one or more multichannel, multiband radio frequency (“RF”) pulses for use with a magnetic resonance imaging (“MRI”) system is provided. The method includes determining a number of RF amplitude modulations and a number of RF phase modulations for each channel in a multichannel RF coil by minimizing an objective function that includes a complex-valued vector. The objective function also contains a system matrix that accounts for both a spatial sensitivity profile of each channel in the multichannel RF coil and a magnetic field map for each excitation band in the multiband RF pulse. | 12-17-2015 |