Patent application number | Description | Published |
20090233337 | Chemoenzymatic Process for the Stereoselective Preparation of (R)-Gamma-Amino-Beta-Hydroxybutyric Acid [(R)-GABOB) and (R)-Carnitine - The present invention provides a chemoenzymatic process for the preparation of (R)-GABOB and (R)-carnitine employing lipase-mediated resolution of 3-hydroxy-4-tosyloxybutanenitrile as the key step. The drawing accompanying this specification represents the preparation of racemic 3-hydroxy-4-tosyloxybutanenitrile, its lipase-mediated kinetic resolution and its successful application in the preparation of (R)-GABOB and (R)-carnitine. | 09-17-2009 |
20100016589 | Novel Anthranilic Acid Derivative as Potential Anticancer Agent and a Process for the Preparation Thereof - The present invention provides novel anthranilic acid derivative useful as potential anticancer agent. More particularly, the present invention relates novel anthranilic acid derivative of general formula (8), R′=alkyl-2-methoxyphenyl piperazine (or) benzyl, R=2 methoxy phenyl, piperazine, 2-pyridyl piperazine, 2-pyrimidyl piperazine, 4-quinazolinyl piperazine, 9H-9-fluorenylamine, 4-{(2{amino-5-(methoxy)-4-[(phenylmethyl)oxy]phenyl}carbonyl)hexahydro-1-pyrazinyl], and [(4[2 amino-4-(benzyloxy)-5-methoxybenzoyl]aminophenyl)sulfonyl]-4-benzamine; X═H (or) pyrazine-2-carbonyl. The present invention also provides a process for the preparation of novel anthranilic acid derivative of general formula (8), which is useful as potential anticancer agent. | 01-21-2010 |
20100113771 | NOVEL BENZOTHIAZOLE AND BENZOXAZOLE LINKED PYRROLO[2,1-C] [1, 4] BENZODIAZEPINE HYBRIDS AS NOVEL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formula (9), useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4][benzodiazepine g hybrids of general formula (9). | 05-06-2010 |
20100174074 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF - Disclosed herein are benzophenone hybrids with potent anticancer activities and processes for creation of the same. | 07-08-2010 |
20110190268 | Novel Benzimidazole Linked Pyrrolo[2,1-c[1,4] Benzodiazepine Hybrids as Potential Antitumour Agents and Process for the Preparation Thereof - The present invention provides a compounds of general formula (8), (11) and (14), useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo [2,1-c][1,4]benzodiazepine hybrids of general formula (8), (11) and (14). | 08-04-2011 |
20120095021 | SYNTHSIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS - The present disclosure provides a compound of general formula A useful as potential anti-tubercular agents. | 04-19-2012 |
20120142913 | BENZYLIDINEANTHRACENONE LINKED PYRROLOBENZODIAZEPINE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of formula 5, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of formula 5a-t. | 06-07-2012 |
20120253034 | PYRROLO[2,1-C][1,4]BENZODIAZEPINE LINKED IMIDAZO[1,5-A]PYRIDINE CONJUGATES AS POTENTIAL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 | 10-04-2012 |
20120271054 | IMIDAZOTHIAZOLE-CHALCONE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compounds 7a-f to 18a-f and 19a-f to 30a-f of general formula A, useful as potential anticancer agents against human cancer cell lines. The present invention further provides a process for the preparation of imidazothiazole-chalcone hybrids 7a-f to 18a-f and 19a-f to 30a-f of general formula A. | 10-25-2012 |
20120283439 | ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a-i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to 37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof. | 11-08-2012 |
20130131336 | CARBAZOLE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEFINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formulae A useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formulae 6a-g, 10a-o, 14a-g and 18a-o. | 05-23-2013 |
20130190489 | QUINOLYLPIPERAZINO SUBSTITUTED THIOLACTONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides compounds of general formulae A, useful as potential anti-tubercular agents against | 07-25-2013 |
20130317011 | DIARYL ETHER LINKED PYRROLO [2,1-c][1,4] BENZODIAZEPINE HYBRIDS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formula A, useful as potential anticancer agents against eleven human cancer cell lines. The present invention further provides a process for the preparation of diaryl ether linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates attached through different alkane spacers of general formula A. | 11-28-2013 |
20130317211 | Pyrrolo[2,1-c][1,4]naphthodiazepine Linked Piperazine Compounds and a Process for the Preparation Thereof - The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R′=(Formula II). n=1-9 and R″=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl | 11-28-2013 |
20130317221 | 3-ARYLETHYNYL SUBSTITUTED QUINAZOLINONE COMPOUNDS - The present invention provides 3-arylethynyl substituted quinazolinone compounds of formula (A) as potential anticancer agents against sixty human cancer cell lines. R | 11-28-2013 |
20130324734 | 2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R | 12-05-2013 |
20140039190 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - Compounds of general formula A useful as potential anticancer agents against human cancer cell lines and a process for the preparation thereof. | 02-06-2014 |
20140336388 | Nitrofurfuryl Substituted Phenyl Linked Piperidino-Oxadiazoline Conjugates As Anti-Tubercular Agents And Process For The Preparation Thereof - The present invention provides nitrofurfuryl substituted phenyl linked piperidino-oxadiazolone compounds of general formula (A) as anti-tubercular agents; wherein G=formula (B); X═H, F; R═H, CH | 11-13-2014 |
20150099888 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof - The present invention provides a compound of general formulae A useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof. | 04-09-2015 |
20150329527 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF - Pyrazole linked benzimidazole conjugates and a method for synthesis of one or more compounds having a pyrazole linked benzimidazole conjugate, particularly pyrazole linked benzimidazole conjugates that are useful as potential antitumor agents against human cancer cell lines, such as leukemia, non-small cell lung cancer, colon cancer, CNS cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer. The process comprises the step of oxidative cyclization of o-phenylenediamines and 3-phenyl-1H-pyrazole-5-carbaldehydes with sodium metabisulphite in ethanol/methanol solvent system at a desired temperature for a period of time to obtain the pyrazole linked benzimidazole conjugate. | 11-19-2015 |
Patent application number | Description | Published |
20090305367 | PROCESS FOR PREPARING LONG-CHAIN DICARBOXYLIC ACIDS - The present invention particularly discovered strains that are capable of producing a long-chain dicarboxylic acid by culturing microorganisms belonging to | 12-10-2009 |
20110046111 | QUINAZOLINE LINKED PYRROLO[2,1-C][1, 4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formula 5, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formula (5): wherein n=3, 4, 5, 6, 8 and wherein R1 and R | 02-24-2011 |
20110190275 | C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO[2,1-C][1,4] BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sodium phosphate buffer at pH of 7.00. The present invention further provides a process for the preparation of C2-Fluoro substituted piperazine linked pyrrolo[2,1c][1-4], benzodiazepine of formula (IX). | 08-04-2011 |
20110201600 | CHALCONE LINKED PYRROLO[2,1-C][1, 4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to chalcone linked pyrrolo[2,1-c][1,4]benzodiazepine hybrids and a process for the preparation there of. More particularly it relates to 7-Methoxy-8-{n[4-1-(2 or 4-substituted phenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one]alkyl}-oxy}-(11aS)-1,2,3,11a-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one and 7-Methoxy-8-{n[-3-(4-hydroxy-3-methoxyphenyl)-1-(2,4-alkyl-3-quinolyl)-2-propen-1-one]alkyl}-oxy-(11aS)-1,2,3,11a-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one with aliphatic chain length variations useful as anticancer (antitumour) agent. The general structural formula of these chalcone linked pyrrolo[2,1-c][1,4]benzodiazepines hybrids is given below. wherein R | 08-18-2011 |
Patent application number | Description | Published |
20090074599 | Stator Casing For Eccentric Worm Pumps - The invention relates to a stator casing for eccentric worm pumps comprising an elastic lining, the cylindrical stator casing having a surface on the inner side, along the longitudinal axis whereof grooves are incorporated. | 03-19-2009 |
20120118916 | FEEDING DEVICE HAVING A DOUBLE-DISK FEED HAVING A SEPARATED DRIVE AND METHOD FOR OPERATING SUCH A FEEDING DEVICE - A feeding device for an in-line screw machine with a shaft rotating in a feed container. A conveying screw is arranged in the direction toward the longitudinal axis of the rotating shaft. At least one disk wheel is allocated to each longitudinal side in the feed container. A separate drive is allocated to each disk wheel for purposes of rotational movement. | 05-17-2012 |
20130094985 | Rotary Piston Pump And Method For Operating A Rotary Piston Pump - A rotary piston pump equipped with a motor having two counter-rotating rotary pistons. The two rotary pistons are housed in an oval pump housing. The two rotary pistons are arranged on a first output shaft and a second output shaft. The first output shaft and the second output shaft are driven and synchronized via at least one elastic element. | 04-18-2013 |
20130129555 | Contact Element For Rotary Piston Pump - The rotary piston pump includes two counter-rotating rotary pistons and an oval pump housing. Every rotary piston has a rotary piston vane and is provided with a contact element. The contact points of the flanks of the two rotary pistons in which the two rotary pistons form a friction pairing are provided with a contact element each. The interior of the oval pump housing is likewise provided with an exchangeable contact element. | 05-23-2013 |
20140014476 | FEEDING DEVICE HAVING A DOUBLE-DISK FEED HAVING A SEPARATED DRIVE AND METHOD FOR OPERATING SUCH A FEEDING DEVICE - A feeding device for an in-line screw machine with a shaft rotating in a feed container. A conveying screw is arranged in the direction toward the longitudinal axis of the rotating shaft. At least one disk wheel is allocated to each longitudinal side in the feed container. A separate drive is allocated to each disk wheel for purposes of rotational movement. | 01-16-2014 |
20140016991 | Joint For The Transmission Of Torques And Axial Forces - The invention discloses a joint for the transmission of torques and axial forces in conjunction with an eccentric rotary motion. In a preferred embodiment, the joint according to the invention is used in an eccentric screw pump for connecting the drive to the pump rotor. The joint connects a coupling rod and a tool and/or a drive to one another. When the joint is used in an eccentric screw pump, the tool is the rotor of the pump. Furthermore, the joint is provided with at least one casing. The axial forces acting on the joint can be transmitted by a first joint part and the torques by a second joint part. | 01-16-2014 |
20140345451 | Method And Device For Fixing And Synchronising Rotary Pistons In A Rotary Piston Pump - A method and a device for fixing and synchronising rotary pistons in a rotary piston pump are disclosed. The rotary pistons are introduced into the pump space of the rotary piston pump. A shaft stub of each rotary piston is then pushed through a pump rear wall onto a driveshaft provided for the respective rotary piston. The rotary pistons are aligned and synchronised in the pump space by means of a template, the template being fixed detachably to a pump housing. The shaft stubs of the respective rotary piston are connected, after the synchronisation, in each case by means of a clamping device in a friction-locked manner to the respective driveshaft, outside the pump space. | 11-27-2014 |
20140348687 | Rotary Piston Pump - A rotary piston pump with at least two double- or multi-lobe rotary pistons rotating in opposite directions, the drive shafts whereof include seals, wherein the seals are constituted as slip ring seals or lip seals or stuffing-box seals, which in each case are disposed on the shaft shoulder belonging to the respective rotary piston, and one slip ring per seal is provided with a locking device, which includes a large number of fixing positions. The seals are pushed onto a tubular shoulder of the rotary piston, the rotary piston is introduced into the pump housing, the securing element is connected to the slip ring seal in a form-fit manner by rotation of the rotary piston and the shaft shoulder is then rigidly connected to the drive shaft. | 11-27-2014 |
20140360359 | Rotary Piston - A rotary piston for a rotary piston pump includes at least one supporting body, through which a rotational axis of the rotary piston extends, and at least one end cap section, which is disposed radially outwards from the at least one supporting body and is connected flexibly, preferably elastically, to the at least one supporting body. | 12-11-2014 |
20150050174 | Rotary Piston Pump With Optimised Inlets And Outlets - A rotary piston pump for the delivery of liquids and for the delivery of liquids containing solids. The rotary piston pump includes a pump housing which is provided with an inlet and an outlet. The pump housing includes a lining. Disposed in the pump housing, or inside the lining, are at least two counter-rotating rotary pistons, which form pump spaces during their rotation. During the rotational movement, the rotary pistons are sealed against one another, against the pump housing and against the lining. Disposed in the pump housing and/or in the lining, in the spatial vicinity of the inlet and/or the outlet, are means with which the pulsation can be reduced or even completely prevented. | 02-19-2015 |
20150086350 | Divided Stator Casing - A stator for eccentric screw pumps with a stator casing for an elastomer body for accommodating a rotor, the elastomer body being provided with at least one collar, wherein the collar is disposed in a recess between the stator casing and a connection body, wherein the fixing of the elastomer body in the stator casing is to be improved. The stator casing includes for this purpose open cavities, recesses and/or elevations at least at one side on the end face. | 03-26-2015 |
Patent application number | Description | Published |
20100268470 | System, Method, and Nanorobot to Explore Subterranean Geophysical Formations - An system and method for exploring geophysical formations at great depths below the surface of the earth. In order to explore the formation, nanorobots with a size less than 500 nanometers are inserted into the formation. The nanorobots propel through the formation, analyzing fluids and conditions as each moves through the formation. The nanorobots can communicate with a machine on the surface via a series of receivers and transmitters located in the wellbore. The machine on the surface is able to combine and analyze the data from the nanorobots to create a three dimensional map of the formation. The map shows the locations of pathways through the formation, pockets of hydrocarbons within the formation, and the boundaries of the formation. | 10-21-2010 |
20150285945 | SYSTEMS, TRANSMITTER ASSEMBLIES, AND ASSOCIATED PROPULSION DEVICES TO EXPLORE AND ANALYZE SUBTERRANEAN GEOPHYSICAL FORMATIONS - Systems and transmitter assemblies for exploring geophysical formations at great depths. In order to explore the formation, transmitter assemblies with a size less than 500 nanometers are inserted into the formation. The transmitter assemblies include propulsion devices to propel through the formation, analyzing fluids and conditions as each moves through the formation. The transmitter assemblies can communicate with a machine on the surface via a series of receivers and transmitters located in the wellbore. The machine on the surface is able to combine and analyze the data from the nanorobots to create a three dimensional map of the formation. The map shows the locations of pathways through the formation, pockets of hydrocarbons within the formation, and the boundaries of the formation. | 10-08-2015 |
20150285946 | SYSTEMS, MACHINES, PROGRAM PRODUCTS, TRANSMITTER ASSEMBLIES AND ASSOCIATED SENSORS TO EXPLORE AND ANALYZE SUBTERRANEAN GEOPHYSICAL FORMATIONS - Systems, methods, and transmitter assemblies for exploring geophysical formations at great depths. In order to explore the formation, transmitter assemblies with a size less than 500 nanometers are inserted into the formation. The transmitter assemblies include sensors and propel through the formation, analyzing fluids and conditions as each moves through the formation. The transmitter assemblies can communicate with a machine on the surface via a series of receivers and transmitters located in the wellbore. The machine on the surface is able to combine and analyze the data from the nanorobots to create a three dimensional map of the formation. The map shows the locations of pathways through the formation, pockets of hydrocarbons within the formation, and the boundaries of the formation. | 10-08-2015 |
20150285948 | SYSTEMS, METHODS, TRANSMITTER ASSEMBLIES, AND ASSOCIATED POWER SUPPLIES AND CHARGING STATIONS TO EXPLORE AND ANALYZE SUBTERRANEAN GEOPHYSICAL FORMATIONS - Systems, methods, and transmitter assemblies for exploring geophysical formations at great depths. In order to explore the formation, transmitter assemblies with a size less than 500 nanometers are inserted into the formation. The transmitter assemblies include power supplies or are charged at charging stations, allowing the transmitter assemblies to propel through the formation, analyzing fluids and conditions as each moves through the formation. The transmitter assemblies can communicate with a machine on the surface via a series of receivers and transmitters located in the wellbore. The machine on the surface is able to combine and analyze the data from the nanorobots to create a three dimensional map of the formation. The map shows the locations of pathways through the formation, pockets of hydrocarbons within the formation, and the boundaries of the formation. | 10-08-2015 |
20150293258 | SYSTEMS, MACHINES, METHODS, AND ASSOCIATED DATA PROCESSING TO EXPLORE AND ANALYZE SUBTERRANEAN GEOPHYSICAL FORMATIONS - Systems, methods, and transmitter assemblies for exploring geophysical formations at great depths. In order to explore the formation, transmitter assemblies with a size less than 500 nanometers are inserted into the formation. The transmitter assemblies propel through the formation, analyzing fluids and conditions as each moves through the formation. The transmitter assemblies can communicate with a machine on the surface via a series of receivers and transmitters located in the wellbore. The machine on the surface is able to combine and analyze the data from the nanorobots to create a three dimensional map of the formation. The map shows the locations of pathways through the formation, pockets of hydrocarbons within the formation, and the boundaries of the formation. | 10-15-2015 |