Kalyanaraman, US
Balaraman Kalyanaraman, Wauwatosa, WI US
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20090170134 | BIFUNCTIONAL AND TRIFUNCTIONAL NITRONE SPIN TRAPPING COMPOUNDS AND USES THEREOF - Methods and compositions for detecting free radicals, the compositions being spin trapping compounds comprising a nitrone having a detecting moiety and optionally having a targeting moiety for targeting the nitrone to an organ, a cell, an organelle or a molecule of interest for directly detecting free radicals, especially free radicals in biological samples. | 07-02-2009 |
20090214437 | In Vivo Mitochondrial Labeling Using Positively-Charged Nitroxide Enhanced and Gadolinium Chelate Enhanced Magnetic Resonance Imaging - A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging data from the subject, and reconstructing an image of the subject having enhanced contrast in areas including metabolic and/or mitotic activity. | 08-27-2009 |
20090220419 | 99mTc-LABELED TRIPHENYLPHOSPHONIUM DERIVATIVE CONTRASTING AGENTS AND MOLECULAR PROBES FOR EARLY DETECTION AND IMAGING OF BREAST TUMORS - Tc-labeled triphenylphosphonium contrasting agents that target the mitochondria and are useful for early detection of breast tumors using scintimammographic imaging. | 09-03-2009 |
20110059922 | MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS - The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked to nitroxide or linked to hydroxylamine anti-oxidant groups. | 03-10-2011 |
20120108549 | NEUROPROTECTIVE COMPOUNDS AND THEIR USE - Apocynin derivative compounds, active pharmaceutical ingredients, dosage forms, and methods of use thereof as neuroprotectants in the brain of mammals. | 05-03-2012 |
20130142735 | In Vivo Mitochondrial Labeling Using Positively-CHarged Nitroxide Enhanced and Gadolinum Chelate Enhanced Magnetic Resonance Imaging - A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging data from the subject, and reconstructing an image of the subject having enhanced contrast in areas including metabolic and/or mitotic activity. | 06-06-2013 |
20130149240 | 99mTc-LABELED TRIPHENYLPHOSPHONIUM DERIVATIVE CONTRASTING AGENTS AND MOLECULAR PROBES FOR EARLY DETECTION AND IMAGING OF BREAST TUMORS - 99mTc-labeled triphenylphosphonium contrasting agents that target the mitochondria and are useful for early detection of breast tumors using scintimammographic imaging. 99mTc-Mito10-MAG3 possesses advantageous radiopharmaceutical properties. The uptake in the myocardium is reduced by one to two orders of magnitude compared to 99mTc-MIBI. 99mTc-Mito10-MAG3 exhibits fast blood clearance, with a blood half-life of less than 2 minutes in rats. A diminished myocardial uptake combined with a prompt reduction of cardiovascular blood pool signal to facilitate improved signal-to-background ratios. | 06-13-2013 |
20130338110 | MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS - The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked to nitroxide or linked to hydroxylamine anti-oxidant groups. | 12-19-2013 |
Karthik Kalyanaraman, Redmond, WA US
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20150324690 | Deep Learning Training System - Training large neural network models by providing training input to model training machines organized as multiple replicas that asynchronously update a shared model via a global parameter server is described herein. In at least one embodiment, a system including a model module storing a portion of a model and a deep learning training module that communicates with the model module are configured for asynchronously sending updates to shared parameters associated with the model. The techniques herein describe receiving and processing a batch of data items to calculate updates. Replicas of training machines communicate asynchronously with a global parameter server to provide updates to a shared model and return updated weight values. The model may be modified to reflect the updated weight values. The techniques described herein include computation and communication optimizations that improve system efficiency and scaling of large neural networks. | 11-12-2015 |
Karthik Kalyanaraman, Bellevue, WA US
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20120130925 | DECOMPOSABLE RANKING FOR EFFICIENT PRECOMPUTING - Methods and computer storage media are provided for generating an algorithm used to provide preliminary rankings to candidate documents. A final ranking function that provides final rankings for documents is analyzed to identify potential preliminary ranking features, such as static ranking features that are query independent and dynamic atom-isolated components that are related to a single atom. Preliminary ranking features are selected from the potential preliminary ranking features based on many factors. Using these selected features, an algorithm is generated to provide a preliminary ranking to the candidate documents before the most relevant documents are passed to the final ranking stage. | 05-24-2012 |
20120130981 | SELECTION OF ATOMS FOR SEARCH ENGINE RETRIEVAL - Methods are provided for populating search indexes with atoms identified in documents. Documents that are to be indexed are identified, and for each document, atoms are identified and are categorized as unigrams, n-grams, and n-tuples. A list of atom/document pairs is generated such that an information metric can be computed for each pair. An information metric represents a ranking of the atom in relation to the particular document. Based on the information metric, some atom/document pairs are discarded and others are indexed. | 05-24-2012 |
20120130984 | DYNAMIC QUERY MASTER AGENT FOR QUERY EXECUTION - A preliminary segment root and a final segment root are selected for each segment. Each time a search query is received, a set of nodes in each segment that will be used to resolve the search query is identified. A preliminary segment root is selected from the set of nodes. Based on statistical data from each node in the set of nodes indicating each node's capability to act as a final segment root that assembles query-execution data, the preliminary segment root algorithmically selects the final segment root. The other nodes in the set of nodes are notified regarding the identity of the final segment root. | 05-24-2012 |
20120130994 | MATCHING FUNNEL FOR LARGE DOCUMENT INDEX - Search results are identified and returned in response to search queries by evaluating and pruning candidate documents in multiple stages. The process employs a search index that indexes atoms found in documents and pre-computed scores for document/atom pairs. When a search query is received, atoms are identified from the search query and a reformulated query is generated based on the identified atoms. The reformulated query is used to identify matching documents, and a preliminary score is generated for matching documents using a simplified scoring function and pre-computed scores in the search index. Documents are pruned based on preliminary scores, and the remaining documents are evaluated using a final ranking algorithm that provides a final set of ranked documents, which is used to generate search results to return in response to the search query. | 05-24-2012 |
20120130995 | EFFICIENT FORWARD RANKING IN A SEARCH ENGINE - Methods and computer storage media are provided for generating entries for documents in a forward index. A document and its document identification are received, in addition to static features that are query-independent. The document is parsed into tokens to form a token stream corresponding to the document. Relevant data used to calculate rankings of document is identified and a position of the data is determined. The entry is then generated from the document identification, the token stream of the document, the static features, and the positional information of the relevant data. The entry is stored in the forward index. | 05-24-2012 |
20120130996 | TIERING OF POSTING LISTS IN SEARCH ENGINE INDEX - A search index includes tiered posting lists. Each posting list in the search index corresponds with a different atom and includes a list of documents containing the particular document. Additionally, a rank is stored with each document listed in a posting list for a given atom representing the relevance of the atom to the context of each document. At least some of the posting lists in the search index are tiered. A tiered posting list is divided into a number of tiers with the tiers being ordered by document while each tier is internally ordered by document. Employing tiered posting lists within the search index allows a search engine to evaluate search queries in a manner that allows for a number of efficiencies and precise stopping. | 05-24-2012 |
20120130997 | HYBRID-DISTRIBUTION MODEL FOR SEARCH ENGINE INDEXES - Methods and systems are provided for using a hybrid-distribution system to identify relevant documents based on a search query. A group of documents is assigned to a particular segment. The group of documents is indexed both by atom and by document to form a reverse index and a forward index. Both indexes are divided amongst each node in that segment so that each node is responsible for storing and accessing a different portion of both the reverse and forward indexes. The reverse index portion is accessed on each of a first set of nodes to identify a first set of documents that is relevant to a particular search query. Document identifications associated with the first set of documents are used to identify a second set of nodes that access their forward index portions to limit the number of relevant documents to a second set of documents. | 05-24-2012 |
20120173510 | PRIORITY HASH INDEX - A priority hash index provides efficient lookup of posting lists for search query terms. The priority hash index is a data structure in which hash values for terms are distributed across multiple storage devices based on importance of the terms and access speeds of the storage devices. Terms are grouped into search lists with each search list including a storage location on each storage device. When a search query is received, a term is identified and hashed to a location on the first storage device and to generate a unique hash value for the term. The locations on the storage device for the term's search list are sequentially read until the hash value for the term is located to access the posting list for the term. | 07-05-2012 |
20130297621 | DECOMPOSABLE RANKING FOR EFFICIENT PRECOMPUTING - Methods and computer storage media are provided for generating an algorithm used to provide preliminary rankings to candidate documents. A final ranking function that provides final rankings for documents is analyzed to identify potential preliminary ranking features, such as static ranking features that are query independent and dynamic atom-isolated components that are related to a single atom. Preliminary ranking features are selected from the potential preliminary ranking features based on many factors. Using these selected features, an algorithm is generated to provide a preliminary ranking to the candidate documents before the most relevant documents are passed to the final ranking stage. | 11-07-2013 |
20140324819 | EFFICIENT FORWARD RANKING IN A SEARCH ENGINE - Methods and computer storage media are provided for generating entries for documents in a forward index. A document and its document identification are received, in addition to static features that are query-independent. The document is parsed into tokens to form a token stream corresponding to the document. Relevant data used to calculate rankings of document is identified and a position of the data is determined. The entry is then generated from the document identification, the token stream of the document, the static features, and the positional information of the relevant data. The entry is stored in the forward index. | 10-30-2014 |
Raghava Kalyanaraman, Lexington, MA US
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20150156230 | METHOD AND SYSTEM FOR SOCIAL COLLABORATIVE CURATION - A social learning and exploration platform to learn about both specific and everyday concepts by exploring an organized collection of multiple flips or media, called flips. Users of the system have the ability to explore a number of categories of content, create and assimilate curated content across those categories, define sets of questions and explore concepts with flips. The system invites crowdsourced perspectives on any concept and expands anyone's search query through invited or crowd sourced collaboration (gain exposure to new facets of a concept through collaborative set creation). | 06-04-2015 |
Raghuraman Kalyanaraman US
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20120096525 | Supporting Compliance in a Cloud Environment - Gathering auditable data concerning actions in a cloud computing environment is automated by determining that one or more auditable data items are available associated with a requester and with at least one application program; responsive to determining that data items are available, transmitting a list of the available auditable data items to a requesting cloud client computer; subsequent to transmitting the list, receiving a data request from the cloud client computer for one or more particular auditable data items from the list; preparing the requested particular auditable data items for transmission according to a predetermined format; and transmitting the prepared requested particular auditable data items to the cloud client computer. Optionally, in some embodiments, the requesting cloud client computer may negotiate a data exchange format with the cloud service provider for receipt of the requested auditable information. | 04-19-2012 |
Rajaramanan Kalyanaraman, Fremont, CA US
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20110073257 | UNITIZED CONFINEMENT RING ARRANGEMENTS AND METHODS THEREOF - An arrangement for performing pressure control in a plasma processing chamber comprising an upper electrode, a lower electrode, a unitized confinement ring arrangement wherein the upper electrode, the lower electrode and the unitized confinement ring arrangement are configured at least for surrounding a confined chamber region to facilitate plasma generation and confinement therein. The arrangement further includes at least one plunger configured for moving the unitized confinement ring arrangement in a vertical direction to adjust at least one of a first gas conductance path and a second gas conductance path to perform the pressure control, wherein the first gas conductance path is formed between the upper electrode and the unitized confinement ring arrangement and the second gas conductance path is formed between the lower electrode and the single unitized ring arrangement. | 03-31-2011 |
20150325414 | UNITIZED CONFINEMENT RING ARRANGEMENTS AND METHODS THEREOF - An arrangement for performing pressure control in a plasma processing chamber comprising an upper electrode, a lower electrode, a unitized confinement ring arrangement wherein the upper electrode, the lower electrode and the unitized confinement ring arrangement are configured at least for surrounding a confined chamber region to facilitate plasma generation and confinement therein. The arrangement further includes at least one plunger configured for moving the unitized confinement ring arrangement in a vertical direction to adjust at least one of a first gas conductance path and a second gas conductance path to perform the pressure control, wherein the first gas conductance path is formed between the upper electrode and the unitized confinement ring arrangement and the second gas conductance path is formed between the lower electrode and the single unitized ring arrangement. | 11-12-2015 |
Ramakrishnan Kalyanaraman, Knoxville, TN US
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20120279561 | Hollow Photovoltaic Fiber - A hollow photovoltaic fiber. The hollow photovoltaic fiber includes semiconductor formed on the inner surface of a hollow tube or on a flexible substrate subsequently formed into a hollow tube. The hollow photovoltaic fiber is suitable a variety of semiconductor devices, including solar cells. Light entering the hollow photovoltaic fiber deposits energy in the semiconductor as it travel through the tube. The hollow photovoltaic fiber exhibits improved energy conversion efficiency over planar thin film solar cells due to the large semiconductor surface area and longer light travel path provided by the tube. Embodiments of the hollow photovoltaic fiber are lightweight and flexible allowing the creation of non-planar solar cells and the applications for solar cells to extend into such areas as the manufacture of photovoltaic textiles or photovoltaic non-woven fabrics. | 11-08-2012 |
Ramnarayan Kalyanaraman US
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20150065509 | HIGHLY 6-SUBSTITUTED -2,4-DIAMINOPYRIMIDINES AS INHIBITORS OF ANTHRAX - 2,4-diaminopyrimidine compounds of generic Formula 1, where R and R′ may be the same or different and are independently selected from: C | 03-05-2015 |
Shankar Kalyanaraman, San Francisco, CA US
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20120284251 | PRIORITIZING CRAWL LISTS USING SOCIAL NETWORKING RANKINGS - Methods, systems, and computer-storage media having computer-usable instructions embodied thereon, for prioritizing crawl lists based on social networking rankings are provided. Various scores are associated with users based on a variety of factors including activity levels with respect to social networking services, activity levels with respect to search engines, and interactions with other users in a social networking environment. The scores are used to compute a ranking for the users and, based on the rankings, a crawl list is prioritized such that content associated with the social networking environment is crawled at an appropriate time. | 11-08-2012 |
20130041876 | LINK RECOMMENDATION AND DENSIFICATION - Links to web content can be identified as a function of one or more links shared by a user of an online social network service, among other things. The identified links can represent recommended links likely to be interesting to the user. Densification techniques can be employed to address data sparsity and thus enhance link recommendation. Furthermore, recommended links can be integrated with a search engine to personalize interaction with web content. | 02-14-2013 |
Shankar Kalyanaraman, New York, NY US
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20140101145 | DYNAMIC CAPTIONS FROM SOCIAL STREAMS - Architecture that augments a search result entry caption with keywords related to topics currently being shared and discussed in other social network information sources. This can provide a much better idea of the content of the website or webpage. The architecture obtains a link from updates of social topics of social network information sources (e.g., social networks for people places professionals, etc.), extracts title content of a document title associated with the link, compares the title content to document text for similarity to create non-duplicative content, creates keywords related to popular social topics from the non-duplicative content, and then augments a search result entry of a search result page with the keywords of the popular social topics. | 04-10-2014 |
Shankari Kalyanaraman, Mountain View, CA US
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20130346969 | Opportunistically Proactive Resource Management Using Spare Capacity - Embodiments perform opportunistically proactive resource scheduling for a plurality of resource-consuming entities. The scheduling is based on both current entitlement (or demand) by the entities and predicted future entitlement (or demand) by the entities. Resources are allocated based on the current demands, while any remaining resource capacity is further allocated to entities based on predicted demands. In some embodiments, the scheduling is performed on a cluster of hosts executing a plurality of virtual machines (VMs) in a virtualized datacenter to implement load balancing. | 12-26-2013 |
Shivkumar Kalyanaraman US
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20130172041 | ONLINE AND DISTRIBUTED OPTIMIZATION FRAMEWORK FOR WIRELESS ANALYTICS - A method, computer program product, and computer system directed to an online and distributed optimization framework for wireless analytics. A radio network controller determines a ranking for each of a plurality of received objects using a plurality of similarity graphs. The radio network controller extracts a common structure by collaborative filtering data associated with a plurality of user devices and the plurality of received objects. The common structure is analyzed to infer usage patterns within a time slot. The radio network controller stores a subset of the ranked objects of the plurality of received objects in response to the analysis. | 07-04-2013 |
Shivkumar Kalyanaraman, Niskayuna, NY US
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20090262646 | Transport protocol for efficient aggregation of heterogeneous losssy paths - A transport protocol that achieves improved performance in an environment where paths are lossy and a plurality of paths are employed to transfer data, essentially in parallel, from a source to a destination. The protocol is implemented with the aid of an aggregate flow manager (AFM) at the source that considers and controls the data flow through the plurality of paths. With some preselected regularity the AFM determines a number of packets to be included in a Forward Error Correction (FEC) block of packets, creates the block, and transmits the segments of the block over the plurality of paths. As necessary, the destination sends information to the source of what additional information needs to be sent. This additional information might be reactive error correcting (RFEC) packets, or a retransmission of the missed packets. | 10-22-2009 |
20110099437 | Loss Tolerant Transmission Control Protocol - A particular device includes a transmitter. The transmitter is adapted to estimate a packet erasure rate for packets of a data window to be transmitted to a receiver. The transmitter is adapted to determine a number of proactive forward error control (FEC) packets for the data window based on the estimated packet erasure rate. The transmitter is adapted to determine a packet size for the packets in the data window based on a window size of the data window and the determined number of proactive FEC packets. The transmitter is also adapted to transmit the data window to the receiver. The packets in the transmitted data window have a size corresponding to the determined packet size and include the determined number of proactive FEC packets. | 04-28-2011 |
Vani Kalyanaraman, St. Louis, MO US
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20140087463 | OPTICAL CONTROL OF CELL SIGNALING - The present invention discloses methods of spatiotemporally controlling G protein signaling in a cell using an artificial optical input. Also disclosed are methods of manipulating cell behavior that is controlled by asymmetrical G protein signaling in a cell. | 03-27-2014 |
Vaniambadi Kalyanaraman, Rockville, MD US
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20110171258 | POLYVALENT, PRIMARY HIV-1 GLYCOPROTEIN DNA VACCINES AND VACCINATION METHODS - Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The compositions and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods for using the protein compositions as boosts following administration of the DNA compositions are provided. | 07-14-2011 |
20140220107 | TRUNCATED HIV ENVELOPE PROTEINS (ENV), METHODS AND COMPOSITIONS RELATED THERETO - The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV. | 08-07-2014 |
Vignesh Kalyanaraman, Boise, ID US
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20100237848 | REFERENCE CIRCUIT WITH START-UP CONTROL, GENERATOR, DEVICE, SYSTEM AND METHOD INCLUDING SAME - A reference generator circuit generates a reference signal for use by a regulator in generating operational power for circuits and devices. A start-up circuit includes a self-biased voltage reference and a differential amplifier configured to generate a start-up signal to induce current flow in response to the voltage independent reference during the start-up phase of the circuit and cease inducing the current flow following the start-up phase of the circuit. The reference signal is generated by receiving a supply voltage and inducing current flow into a node of a bandgap reference circuit during a start-up phase of the bandgap reference circuit and ceasing inducing the current flow following the start-up phase of the bandgap reference circuit. | 09-23-2010 |
Viswanathan Kalyanaraman, Newburgh, IN US
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20120245239 | FAST DISSOLVING POLYIMIDE POWDERS - Polyetherimide particles or powders with a high surface area and high porosity can be prepared by precipitation of polymer solution in hot water or steam without the use of any additives. The particles or powders produced rapidly dissolved in organic solvents as well as epoxy matrices. | 09-27-2012 |
Viswanathan Kalyanaraman, Athens, OH US
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20100093915 | IMPACT-MODIFIED MOLDING COMPOSITION AND METHOD - A method is disclosed for preparing an acrylic-styrene-acrylonitrile (ASA) resin, which comprises the steps of: (a) polymerizing a mixture comprising at least one acrylate monomer and at least one polyethylenically unsaturated monomer to form a rubber substrate, followed by (b) polymerizing a mixture of monomers in the presence of the rubber substrate, at least one of which monomers is selected from the group consisting of vinyl aromatic monomers and at least one of which monomers is selected from the group consisting of monoethylenically unsaturated nitrile monomers, and optionally followed by (c) polymerizing one or more monomers in at least one subsequent stage in the presence of the rubber substrate from (b), wherein the one or more monomers comprise at least one monomer selected from the group consisting of (C | 04-15-2010 |