Patent application number | Description | Published |
20080249279 | Acid Groups-Containing Polyurethane Resins - Water-dilutable polyurethane resins with acid groups, wherein the polyurethane resins contain units derived from oils A which are at least partly unsaturated, from olefinically unsaturated aliphatic acids B or anhydrides B′ thereof, from compounds C having functional groups which are reactive towards acid groups or acid anhydride groups, selected from the group consisting of epoxide groups, hydroxyl groups, mercaptan groups and amino groups, and which react in the reaction with the compounds B or B′ to form an ester group, a thioester group or an acid amide group, where the compounds C are selected from the group consisting of compounds C″ which additionally contain sulfonic acid groups, or carboxylic acid groups which are activated by electron-withdrawing substituents, and compounds C′ which additionally contain at least one hydroxyl group which is retained during the reaction with the compounds B or B′, and where at least a mass fraction of 25% of the compounds C consists of compounds C″, and polyfunctional isocyanates D, a process for their preparation, their use as catalysts in the curing of binders containing hydroxyl groups with aminoplast resins, and stoving paints which contain these catalysts | 10-09-2008 |
20120269974 | AQUEOUSLY DISPERSIBLE POLYURETHANE - The invention relates to an aqueously dispersible polyurethane having a specific amount of substance of hydroxyl groups, —OH, of at least 0.6 mol/kg, and additionally satisfying at least two of the following conditions: a) a degree of branching measured as specific amount of substance of tertiary and/or quaternary aliphatic carbon atoms of from 0.01 mol/kg to 0.5 mol/kg, b) a specific amount of urea groups >N—CO—N< of from 0.8 mol/kg to 2 mol/kg, and c) a specific amount of substance of hydroxyl groups, —OH, of from 1 mol/kg to 4 mol/kg, wherein in each case the specific amount of substance is based on the mass of the polyurethane, a process for the preparation thereof, and a method of use thereof. | 10-25-2012 |
Patent application number | Description | Published |
20080274014 | Diagnostic Device for Testing Hydration and Other Conditions - Devices for the non-invasive collection of a liquid sample in small quantities, such as urine for testing hydration in infants and incontinent adults, directly at the source of that sample, isolation of the collected sample from a testing site, the transportation of that sample to a site for testing contained within the device itself, and the selective application of some or all of the specimen to a testing apparatus contained within the device itself, with a minimum of specimen handling required. Other aspects include a method and device for facilitating the reading of the result of the specimen test by a skilled or unskilled user, including means for determining that no adequate sample has been delivered to the testing site. | 11-06-2008 |
20080274495 | Diagnostic Method for Testing Hydration and Other Conditions - Methods for the non-invasive collection of a liquid sample in small quantities, such as urine for testing hydration in infants and incontinent adults, directly at the source of that sample, isolation of the collected sample from a testing site, the transportation of that sample to a site for testing contained within the device itself, and the selective application of some or all of the specimen to a testing apparatus contained within the device itself, with a minimum of specimen handling required. Other aspects include a method and device for facilitating the reading of the result of the specimen test by a skilled or unskilled user, including means for determining that no adequate sample has been delivered to the testing site. | 11-06-2008 |
Patent application number | Description | Published |
20090084377 | ENDOTRACHEAL TUBE PROTECTOR - A endotracheal tube protector for use with an endotracheal tube comprises an elongated tubular member having a first end configured to extend out of a patient's mouth when in use and a second end configured to enter the throat of the patient. The tubular member has openings in the first and second ends and defines a substantially cylindrical cavity with an interior wall configured to hold an endotracheal tube therewithin. The tubular member has a longitudinal slit for inducing radial expansion of the cavity and a pair of opposed bosses formed longitudinally in the tubular member at positions adjacent to the slit. The opposed bosses are configured to project into the cavity and to transmit a clamping force onto the endotracheal tube when contacted by the upper teeth of the patient when the endotracheal tube protector is in use and oriented such that the slit faces toward the roof of the patient's mouth. | 04-02-2009 |
20110180065 | ENDOTRACHEAL TUBE PROTECTOR - An endotracheal tube protector for use with an endotracheal tube comprises an elongated tubular member having a first end configured to extend out of a patient's mouth when in use and a second end configured to enter the throat of the patient. The tubular member has openings in the first and second ends and defines a substantially cylindrical cavity to hold an endotracheal tube. The tubular member has a longitudinal slit to allow the walls to separate for radial expansion of the cavity. The wall thickness is non-constant, with a thin-walled region which flexes to permit the walls to separate, and a thick-walled region which resists crushing forces acting on the protector. A pair of opposed bosses may extend longitudinally adjacent to the slit, to transmit a clamping force onto the endotracheal tube when contacted by the patient's jaw. | 07-28-2011 |
20120083816 | BLADE UNIT FOR SURGICAL SCALPEL - A scalpel is disclosed, having a conventional handle and a blade unit for releasable attachment to the handle. The blade unit includes a body, a slot within said body to releasably engage the finger protruding from the handle, a scalpel blade attached to said body, and a blade cover slideably engaged to said body and configured for movement between a forward, protective position fully covering said blade and a retracted position to expose said blade for use. The cover has open front and rear ends to permit said blade and said body respectively to protrude through opposing ends of said cover when said cover is moved between said positions. | 04-05-2012 |
20130186406 | GAS DELIVERY MASK FOR MEDICAL USE - There is provided a mask for delivery of a medical gas to a patient comprising a mask body having a rim for contacting the patient's face and an interior space configured to surround and enclose the patient's nose and mouth. The mask includes a gas diffuser structure projecting through said mask body into said interior space. The gas diffuser structure includes a support, a gas delivery tube within said support having an internal bore the axis of which is generally vertical when said mask body is upright, an inlet in said gas tube for communication with a source of pressurized gas, and an outlet from said gas tube within said interior space. The structure includes a gas flow disrupter or baffle located over the outlet of said bore in the path of gas exiting said bore configured to diffuse and/or redirect said gas radially outwardly. A flow of gas entering the mask forms a plume of enriched gas at the patient's nose and mouth region, thereby permitting a relatively high oxygen content to be delivered to the patient at a lower flow rate. | 07-25-2013 |
Patent application number | Description | Published |
20100302060 | METHODS FOR CLOSK SYNCRONIZATION IN WELLBORE INSTRUMENTS - A method for synchronizing a clock in a device at the Earth's surface with a device disposed in a wellbore includes generating a time datum for a signal generated at at least one of the surface and in the wellbore proximate an end of the pipe string. A time delay is determined between detection of the signal at the at least one repeater and retransmission of the signal from the at least one repeater. The time datum is appended with a signal corresponding to the time delay. The retransmitted signal is detected at the other of proximate the end of the pipe string and at the surface. | 12-02-2010 |
20110050452 | SYSTEM AND METHOD FOR COMMUNICATING DATA BETWEEN WELLBORE INSTRUMENTS AND SURFACE DEVICES - A method for communicating signals between an instrument in a wellbore and a device at the Earth's surface using a wired drill pipe telemetry channel includes allocating signals generated by at least one instrument in the wellbore to a plurality of buffers. Each buffer represents data having a respective communication priority. Signals from each buffer are communicated to the wired drill pipe telemetry channel according to a predetermined priority procedure. The procedure allocates telemetry channel priority related to the communication priority. | 03-03-2011 |
20110226470 | SYSTEMS AND METHODS FOR PROVIDING WIRELESS POWER TRANSMISSIONS AND TUNING A TRANSMISSION FREQUENCY - A system transmits a wireless power transmission from a bottom hole assembly of a drill string. The system has a downhole component having a wireless power transmitter adapted to wirelessly transmit at least one wireless power transmission and a wireless power receiver adapted to receive the at least one wireless power transmission. | 09-22-2011 |
20110309948 | SYNCHRONIZATION BETWEEN DEVICES - The present disclosure relates to a method to determine a clock signal when separate clocks are used. In one embodiment, a disciplined clock system comprising an update subsystem and a synthesis subsystem is provided. A first clock phase estimate is provided to the update subsystem and used, along with the update subsystem, to determine a frequency offset estimate and a phase offset estimate. The clock signal is determining using the frequency offset estimate, the phase offset estimate, and the synthesis subsystem. Alternatively, two clocks can be synchronized by generating a signal associated with a first clock; modulating the signal; transmitting the modulated signal; receiving the modulated signal by a receiver associated with a second clock; correlating the received signal; determining the time of arrival of the received signal; determining the time difference between the two clocks; and synchronizing the two clocks. | 12-22-2011 |
20120001629 | NON-RESONANT LOGGING TOOLS - Methods and systems are provided for tools having non-resonant circuits for analyzing a formation and/or a sample. For example, nuclear magnetic resonance and resistivity tools can make use of a non-resonant excitation coil and/or a detection coil. These coils can achieve desired frequencies by the use of switches, thereby removing the requirement of tuning circuits that are typical in conventional tools. | 01-05-2012 |
20120112924 | Systems and Methods for Providing a Wireless Power Provision and/or an Actuation of a Downhole Component - Systems and methods provide wireless power and actuation of a downhole component within a borehole formed in a formation. The systems and method have a first downhole component positioned within the borehole and connected to and/or in communication with a power source. A wireless transmitter is electrically connected to the first component and is adapted to wirelessly transmit electrical power. A second downhole component is in communication with the wireless transmitter to receive the electrical power from the wireless transmitter. The second component is actuated upon receiving the electrical power to perform a task related to the borehole or formation about the borehole. | 05-10-2012 |
20130021166 | SYSTEM AND METHOD FOR BOREHOLE COMMUNICATION - To produce a desired telemetry signal, the desired telemetry signal is first determined and then decomposed into two or more component signals. For each component signal, commands are sent to an individual modulator. The individual modulators each produce individual signals according to their received commands. The individual signals from each individual modulator are combined to produce the desired telemetry signal, or the individual signals from each individual modulator are allowed to combine to produce the desired telemetry signal. A telemetry system that produces such desired telemetry signals includes an uplink transmitter/receiver pair, a downlink transmitter/receiver pair, or both pairs, wherein each uplink transmitter and each downlink receiver is disposed in a wellbore. Two or more modulators are provided, as is a telemetry signal generator having a processor capable of decomposing a desired telemetry signal into two or more component signals and issuing commands to control the two or more modulators. | 01-24-2013 |
20130082845 | ESTIMATION AND COMPENSATION OF PRESSURE AND FLOW INDUCED DISTORTION IN MUD-PULSE TELEMETRY - A method for reconstituting a signal due to a flow distortion in a mud-pulse telemetry system, having steps of obtaining at least one parameter to be transmitted by a transmitter to a receiver through the mud-pulse telemetry system, estimating a change in a flow rate in a borehole fluid along a trajectory of the mud-pulse telemetry system undergoing a fluid distortion, estimating a Doppler rate of the signal traveling through the borehole fluid along the trajectory of the mud-pulse telemetry system, calculating a Doppler compensation value for the signal sent along the trajectory in the borehole fluid, transmitting the signal of the at least one parameter through the mud-pulse telemetry system, receiving a portion of the signal of the at least one parameter and reconstituting at least a portion of the signal using the Doppler compensation value. | 04-04-2013 |
20130106614 | SYNCHRONIZATION BETWEEN DEVICES | 05-02-2013 |
20130146279 | SYSTEM AND METHOD FOR BOREHOLE COMMUNICATION - A method and an apparatus for communicating between a tool and a surface of a subterranean formation including a signal generator configured to send a signal through the formation, a relay in communication with the generator, and a receiver in communication with the relay. A method and an apparatus for communicating between a tool and a surface of a subterranean formation including sending a signal from a generator configured to send a signal through a formation, receiving the signal at a relay, sending a second signal from the relay, and receiving the second signal at a receiver. | 06-13-2013 |
20130251083 | Synchronization Between Devices - The present disclosure relates to a method to determine a clock signal when separate clocks are used. In one embodiment, a disciplined clock system comprising an update subsystem and a synthesis subsystem is provided. A first clock phase estimate is provided to the update subsystem and used, along with the update subsystem, to determine a frequency offset estimate and a phase offset estimate. The clock signal is determining using the frequency offset estimate, the phase offset estimate, and the synthesis subsystem. Alternatively, two clocks can be synchronized by generating a signal associated with a first clock; modulating the signal; transmitting the modulated signal; receiving the modulated signal by a receiver associated with a second clock; correlating the received signal; determining the time of arrival of the received signal; determining the time difference between the two clocks; and synchronizing the two clocks. | 09-26-2013 |
20150109140 | Compression and Timely Delivery of Well-Test Data - A modem is described having a transceiver assembly, a non-transitory processor readable medium coupled to the transceiver assembly, transceiver electronics coupled to the transceiver and the non-transitory processor readable medium, and a power supply supplying power to the transceiver assembly and the transceiver electronics. The transceiver electronics are configured to calculate a size of an output bit stream based on an encoding scheme to encode for transmission data stored in the non-transitory processor readable medium, decimate the data if the size of the output bit stream exceeds a predetermined size, recalculate the size of the output bit stream, after decimation of the data, based on the encoding scheme to encode for transmission the decimated data, and encode the data using the encoding scheme. | 04-23-2015 |
Patent application number | Description | Published |
20120018279 | DEVICE AND METHOD FOR PRODUCING TUBES - A device for production of tubes, includes a plurality of mandrel assemblies, each comprising multiple mandrels on which the tubes can be produced in steps at a plurality of work stations, wherein the mandrel assemblies can be transported from work station to work station using transport means. The mandrels of at least one of the mandrel assemblies are distributed into a first and at least a second mandrel group, and in at least one of the work stations the first mandrel group can be moved from a processing position associated with the work station, in which the work station can interact with the first mandrel group to a park position associated with the work station, and the second mandrel group can be moved from a park position associated with the work station to a processing position associated with the work station. | 01-26-2012 |
20140255637 | METHOD FOR PRODUCING TUBULAR BODIES FOR PACKAGING TUBES, AND A PACKAGING TUBE - A method for manufacturing tubular bodies ( | 09-11-2014 |
20140318682 | DEVICE AND METHOD FOR MANUFACTURING TUBE BODIES - A device for manufacturing circumferentially closed tubular tube bodies, comprising conveying means for conveying the substrate in a conveying direction, and also comprising tube-forming means which are designed to form a web-like substrate, which has a first and a second longitudinal edge, into a tubular form in which, in the circumferential direction, the first and the second longitudinal edge form or delimit a contact region, in particular abutting or overlapping region, which extends in the conveying direction, wherein the tube-forming means effect the shaping of the substrate into the tubular form in a shaping region and comprise welding means for welding the tubular form at a weld circumferential position, first sensor means, which are upstream of the shaping region; in the conveying direction, for detecting the position of the substrate web, setting means for setting the position of the substrate web transversely with respect to the conveying direction, and first control means which are designed to actuate the setting means, taking into consideration the measurement values from the first sensor means, such that the web-like substrate is held in a setpoint position transversely with respect to the conveying direction or such that the web-like substrate is adjusted in the direction of the setpoint position. | 10-30-2014 |
20140338779 | METHOD FOR PRODUCING TUBULAR BODIES FOR PACKAGING TUBES, AND A PACKAGING TUBE WITH A TUBULAR BODY - A method for manufacturing tubular bodies ( | 11-20-2014 |
Patent application number | Description | Published |
20090300289 | Reducing back invalidation transactions from a snoop filter - In one embodiment, the present invention includes a method for receiving an indication of a pending capacity eviction from a caching agent, determining whether an invalidating writeback transaction from the caching agent is likely for a cache line associated with the pending capacity eviction, and if so moving a snoop filter entry associated with the cache line from a snoop filter to a staging area. Other embodiments are described and claimed. | 12-03-2009 |
20100161907 | POSTING WEAKLY ORDERED TRANSACTIONS - A processor may comprise a core area, a control unit, an uncore area. The core area may comprise multiple processing cores and line-fill buffers. A first processing core of the core area may store a first weakly ordered transaction in a first line-fill buffer. The firs processing core may offload the first weakly ordered transaction to the extended buffer space provisioned in the uncore area after receiving a request from the uncore area. The first processing core may then de-allocate the first line-fill buffer after the first weakly ordered transaction is offloaded to the extended buffer space. The uncore may then post the first weakly ordered transaction to a memory or a memory system. The control unit may track the first weakly ordered transaction to ensure that the first weakly ordered transaction is posted to the memory or the system. | 06-24-2010 |
20110320893 | G-ODLAT On-die Logic Analyzer Trigger with Parallel Vector Finite State Machine - An apparatus for debugging internal signals of integrated circuits is presented. In one embodiment, the apparatus comprises a number of vector registers associated with states of a state machine. A group of registers, associated with a state of the state machine, comprises a mask register an arm register. A comparator compares debug data with contents of the mask register and the arm register to determine a comparison result to be stored in one or more bit positions of the vector register. The apparatus further comprises a triggering logic unit to determine whether or not to trigger a fire event based on the vector registers. | 12-29-2011 |
20140380081 | Restricting Clock Signal Delivery In A Processor - In an embodiment, a processor includes a core to execute instructions, where the core includes a clock generation logic to receive and distribute a first clock signal to a plurality of units of the core, a restriction logic to receive a restriction command and to reduce delivery of the first clock signal to at least one of the plurality of units. The restriction logic may cause the first clock signal to be distributed to the plurality of units at a lower frequency than a frequency of the first clock signal. Other embodiments are described and claimed. | 12-25-2014 |
20150188797 | ADAPTIVE ADMISSION CONTROL FOR ON DIE INTERCONNECT - Methods and apparatus relating to adaptive admission control for on die interconnect are described. In one embodiment, admission control logic determines whether to cause a change in an admission rate of requests from one or more sources of data based at least in part on comparison of a threshold value and resource utilization information. The resource utilization information is received from a plurality of resources that are shared amongst the one or more sources of data. The threshold value is determined based at least in part on a number of the plurality of resources that are determined to be in a congested condition. Other embodiments are also disclosed. | 07-02-2015 |
Patent application number | Description | Published |
20100305951 | Methods And Systems For Resolving The Incompatibility Of Media Items Playable From A Vehicle - A system for monitoring hands-free accessibility of media items for play at a vehicle includes a vehicle entertainment computing system (VECS) configured to receive predetermined rules for voice-activated access of the media items. Violations of the rules are detected based on media item metadata. If a violation is detected, a prompt is outputted. Media items are retrieved and played based on voice-activated requests. One embodiment includes a method for monitoring hands-free accessibility of media items for play at a vehicle. A system for formatting media items for accessibility at a VECS includes a media item incompatibility resolution system (MIIRS) configured to resolve violations of the predetermined rules by receiving additional rules relating to formatting violating media items. The media items are searched and the violations addressed by reformatting the media items for voice-activated access. The media items are outputted to the MIIRS. | 12-02-2010 |
20110295444 | METHODS AND SYSTEMS FOR IMPLEMENTING AND ENFORCING SECURITY AND RESOURCE POLICIES FOR A VEHICLE - In one or more embodiments, a vehicle resource usage control system includes a vehicle computer having security policies that define usage rules for one or more vehicle resources. One or more devices communicating with the vehicle computer may have installed in memory software applications that use one or more vehicle resources for operation. Programmed instructions may be received that define which of the one or more vehicle resources the software applications use for operation. These programmed instructions may be associated with the one or more security policies. The security policy associated with the software applications may be determined based on the programmed instructions. Operation of the software applications may be permitted according to the security policy. | 12-01-2011 |
20110296037 | METHODS AND SYSTEMS FOR INTERFACING WITH A VEHICLE COMPUTING SYSTEM OVER MULTIPLE DATA TRANSPORT CHANNELS - In one or more embodiments, two or more devices may interface with a computing system over multiple communication channels. A connection may be established between a computing system and two or more devices communicating data using different communication protocols. The communication protocol of the two or more devices may be determined and a general transport protocol for communicating data with the two or more devices based on the respective communication protocols may be imposed on the communication protocol of the two or more devices. Data may be communicated with the two or more devices based on the general transport protocol. An event may be performed at the vehicle computing system or the two or more devices based on the data. | 12-01-2011 |
20120041633 | SYSTEMS AND METHODS FOR REGULATING CONTROL OF A VEHICLE INFOTAINMENT SYSTEM - One or more embodiments include systems and methods for regulating control of a vehicle infotainment system. In one embodiment, a vehicle computing system includes a user interface which has one or more output components and one or more input components. Software executing in memory of the vehicle computing system may be programmed with rules to reduce driver distraction such as preventing inputs or outputs during vehicle operation. Inputs may be intercepted from the one or more input components of the user interface. Additionally or alternatively, outputs may be intercepted to the output components of the user interface. The intercepted inputs or intercepted outputs may be evaluated for one or more violations based on the rules. If the one or more violations are detected, the inputs or outputs may be prevented during vehicle operation. | 02-16-2012 |
20130262552 | Methods and Apparatus for Remote Activation of an Application - An application activation method includes interfacing a vehicle computing system with a remote device using an interface protocol. The method also includes sending a query from the vehicle computing system to the remote device to determine applications and/or services available on the remote device that are capable of interaction with the vehicle computing system. Once the applications have been determined, the method includes selecting, at the vehicle computing system, an application or service from the determined available applications and/or services for interaction. The method also includes sending an instruction from the vehicle computing system to an agent on the remote device, the instruction including an indication that the selected application or service is to be activated. Finally, the method includes receiving confirmation, at the vehicle computing system, that the application or service has been activated. | 10-03-2013 |
20130311036 | Method and Apparatus for Interactive Vehicular Advertising - A system includes a processor configured to wirelessly communicate with a remote application. The system also includes one or more outputs, controllable by the processor. The processor is configured to receive an advertisement for playback on at least one output, determine the suitability of the received advertisement for playback, permit or deny advertisement playback based on the suitability of the advertisement, and provide access to the at least one output upon permitting advertisement playback. | 11-21-2013 |
20140129339 | Method and Apparatus for Digital Coupon Presentation - A system includes a processor configured to receive a plurality of media elements including at least one media element containing an interactive advertisement. The processor is further configured to present the media elements to a vehicle occupant. The processor is also configured to receive acquiescence to store a coupon associated with at least one interactive advertisement. Additionally, the processor is configured to instruct storage of the coupon and instruct storage of any events associated with the coupon which may signal a reason to re-present the coupon to a driver. | 05-08-2014 |
20140221033 | System and Method of Arbitrating Audio Source Streamed by Mobile Applications - A system for attenuating vehicle audio for mobile application audible statements, the system comprising a vehicle computing system having one or more processors for playing audio in the vehicle from a plurality of different audio sources. The system also includes a wireless transceiver for communicating signals from a mobile computing device for processing by the vehicle computing system. The vehicle computing system is configured to receive a wireless signal from the mobile computing device representative of an audible statement to be played in the vehicle. If the vehicle computing system is playing audio in the vehicle at the time the wireless signal is received from the mobile computing device, determine an amount to attenuate the audio based on the source of the audio. Attenuate the audio and play the audible statement based on the determination. | 08-07-2014 |
20150161832 | Method and Apparatus for Virtual Key Delivery - A system includes a processor configured to receive a request for temporary vehicle usage. The processor is also configured to associate a requesting user with an available vehicle and generate a temporary vehicle access code and start code, usable during a predetermined time period. The processor is further configured to send the access code and start code to both the user and the vehicle. | 06-11-2015 |
20150373175 | System and Method of Arbitrating Audio Source Streamed by Mobile Applications - A system for attenuating vehicle audio for mobile application audible statements, the system comprising a vehicle computing system having one or more processors for playing audio in the vehicle from a plurality of different audio sources. The system also includes a wireless transceiver for communicating signals from a mobile computing device for processing by the vehicle computing system. The vehicle computing system is configured to receive a wireless signal from the mobile computing device representative of an audible statement to be played in the vehicle. If the vehicle computing system is playing audio in the vehicle at the time the wireless signal is received from the mobile computing device, determine an amount to attenuate the audio based on the source of the audio. Attenuate the audio and play the audible statement based on the determination. | 12-24-2015 |
20160075232 | INTERNAL VEHICLE TELEMATICS DATA ACCESS - A nomadic device may connect to a vehicle computing system (VCS) and be configured to identify data element parameter information associated with a gauge to be displayed, capture, using a data bridge adapter connected to a vehicle network, an element of vehicle data according to the data element parameter information, and display, via the VCS, the gauge including the element of vehicle data formatted according to the data element parameter information. A VCS may be configured to receive filtered vehicle data from a telematics gateway configured to provide a subset of vehicle data provided over a vehicle network, receive vehicle data from a nomadic device in communication with a data bridge adapter configured to capture vehicle data provided over the vehicle network, and utilize the vehicle data to provide information via the VCS unavailable via the filtered vehicle data. | 03-17-2016 |
Patent application number | Description | Published |
20090069334 | Pyridazine based alpha-helix mimetics - The synthesis of new α-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available building block, 6. These scaffolds may be thought of as synthetic counterparts of amphiphilic α-helices having a “wet face” along one side and a hydrophobic face along the other side of the helix. | 03-12-2009 |
20090197895 | OXAZOLE-PYRROLE-PIPERAZINE ALPHA-HELIX MIMETIC - Amphiphilic α-helix mimetics are provided. These compounds are constructed using an oxazole-pyrrole-piperazine (OPP) scaffold. The amphiphilic α-helix mimetics are also employable for making libraries and for treating diseases or conditions effected by the inhibition or disruption of interactions with the alpha helix of a protein. | 08-06-2009 |
20090298835 | NOVEL SCAFFOLDS FOR ALPHA-HELIX MIMICRY - Functionalized pyridazine derivatives having a low molecular weight and pharmaceutical compositions thereof are useful as alpha-helix mimetics and for treating conditions and/or disorders mediated by alpha-helix-binding receptors and proteins. | 12-03-2009 |
20100022549 | ALPHA-HELIX MIMETIC WITH FUNCTIONALIZED PYRIDAZINE - The synthesis of new α-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available dimethyl pyridazine-3,6-dicarboxylate building block. These scaffolds may be thought of as synthetic counterparts of amphiphilic α-helices having a hydrophilic face along one side and a hydrophobic face along the other side of the helix. | 01-28-2010 |
20100113466 | OXAZOLE-PYRIDAZINE-OXAZOLE ALPHA-HELIX MIMETIC - There are provided alpha helix scaffolds mimicking i, i+3/i+4, i+7 or i+11 residues having the general structure oxazole-pyridazine-piperidine or oxazole-pyridazine-oxazole. The common pyridazine heterocycle originates from substituted or unsubstituted dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate. These scaffolds are synthetic counterparts of amphiphilic alpha helices having a hydrophilic face along one side and a hydrophobic face along the other side of the helix. | 05-06-2010 |
Patent application number | Description | Published |
20140053956 | METHOD FOR MANUFACTURING A THREE-DIMENSIONAL ARTICLE - The disclosure refers to a method for manufacturing a three-dimensional article, the method including successively building up the article from a metallic base material by means of an additive manufacturing process, thereby creating an article with a substantial anisotropy of its properties and heat treating the manufactured article at a sufficiently high temperature to reduce the anisotropy significantly by recrystallization and/or grain coarsening. | 02-27-2014 |
20140154088 | METHOD FOR MANUFACTURING A METALLIC COMPONENT BY ADDITIVE LASER MANUFACTURING - The invention refers to a method for manufacturing a three-dimensional metallic article/component entirely or partly. The method includes a) successively building up said article/component from a metallic base material by means of an additive manufacturing process by scanning with an energy beam, thereby b) establishing a controlled grain orientation in primary and in secondary direction of the article/component, c) wherein the secondary grain orientation is realized by applying a specific scanning pattern of the energy beam, which is aligned to the cross section profile of said article/component, or with characteristic load conditions of the article/component. | 06-05-2014 |
20140242400 | METHOD FOR MANUFACTURING A HYBRID COMPONENT - The invention refers to a method for manufacturing a hybrid component including the following steps of manufacturing a preform as a first part of the hybrid component, then successively building up on that preform a second part of the component from a metallic powder material by means of an additive manufacturing process by scanning with an energy beam, thereby establishing a controlled grain orientation in primary and in secondary direction of at least a part of the second part of the component. The controlled secondary grain orientation is realized by applying a specific scanning pattern of the energy beam, which is aligned to the cross section profile of the component or to the local load conditions for the component. | 08-28-2014 |
20150198052 | METHOD FOR MANUFACTURING A METALLIC OR CERAMIC COMPONENT BY SELECTIVE LASER MELTING ADDITIVE MANUFACTURING - The invention refers to a method for selective laser melting additive manufacturing a three-dimensional metallic or ceramic article/component entirely or partly. The method includes successively building up said article/component layer by layer directly from a powder bed of a metallic or ceramic base material by means of remelting the layers with a high energy laser beam, moving repetitively across the areas, which are to be solidified. The movement of the laser beam is made of a superposition of a continuous linear movement and at least one superimposed oscillation with a determined frequency and amplitude. The oscillation is created by a beam deflection device and the same beam deflection device is also used for linear positioning movement. | 07-16-2015 |