Patent application number | Description | Published |
20080233267 | Coated Stent With Evenly Distributed Therapeutic Agent - A stent includes a stent framework and a coating disposed on the stent framework. The coating includes an inner surface and an outer surface. The coating has a circumferential therapeutic concentration zone near the inner surface and a circumferential washed zone near the outer surface. | 09-25-2008 |
20080234808 | Releasable Polymer on Drug Elution Stent and Method - A method for treating a vascular condition is disclosed, the method comprising delivering a stent to a target region of a vessel, the stent including a drug polymer coating including an elution portion and a remaining portion, eluting the elution portion from the delivered stent for an elution period, heating the delivered stent after the elution period; and removing the remaining portion based on the heating. | 09-25-2008 |
20080255658 | Degradation Associated Drug Delivery for Drug Eluting Stent and Medical Device Coatings - A system for treating a vascular condition includes a stent having a biodegradable coating on the stent framework. The coating releases a therapeutically effective amount of therapeutic agent as a function of degradation of the coating. Also provided is a method of treating a vascular condition by placing a stent having a biodegradable coating at a treatment site and delivering a therapeutically effective amount of therapeutic agent at the treatment site as a function of degradation of the coating. Also provided is a method of improving the performance of a medical device by including a biodegradable coating on the surface of the device and releasing a therapeutically effective amount of a therapeutic agent at the treatment site as a function of degradation of the coating. | 10-16-2008 |
20080306581 | Streamlined Stents - A stent for implantation within the body of a patient is disclosed. The stent can be formed from one or more stent modules comprising a plurality of stent struts, one or more of which have an inner contour designed for streamlined fluid flow when the stent is implanted within an anatomical passageway of the patient. | 12-11-2008 |
20090024209 | Hypotubes for Intravascular Drug Delivery - An implantable device capable of delivering drugs is disclosed. An example of the device is a stent that comprises at least one hypotube having a lumen and one or more pores. The lumen of the hypotube is configured to retain drugs that can be eluted through the one or more pores after deployment at a treatment site. | 01-22-2009 |
20090035351 | Bioabsorbable Hypotubes for Intravascular Drug Delivery - A biodegradable implantable device for delivering a drug to a treatment site includes a biodegradable hypotube defining a lumen and at least one drug disposed within the lumen of the hypotube. At least one drug is released from the lumen upon degradation of the biodegradable hypotube. The lumen may be compartmentalized, each compartment containing a different drug. The hypotube may also include a plurality of pores in fluid communication with the compartments providing different drug release profiles. | 02-05-2009 |
20090240238 | Clot Retrieval Mechanism - A clot retrieval device for removing thrombi or other emboli from a body lumen is disclosed. The clot retrieval device includes an elongate shaft portion, a self-expanding snare disposed at a distal end of the shaft portion and a flexible bag portion attached to the self-expanding snare. The snare may be a loop or circlet formed in a distal end of the elongate shaft portion or may be a separate component attached thereto. An opening of the bag portion for receiving the thrombi or emboli there through faces proximally when the snare is fully deployed. The bag portion is made of a flexible, non-porous material, such as a balloon-type or elastomeric material, that is foldable or otherwise collapsible to achieve a low-profile while the clot retrieval device is being tracked to the treatment site through the body lumen. | 09-24-2009 |
20090269480 | Supercritical Fluid Loading of Porous Medical Devices With Bioactive Agents - Described herein are implantable medical devices that can be coated with polymers and/or bioactive agents with the aid of supercritical fluids and methods for coating the devices. The medical devices described herein can have at least a portion of their surface made of or formed from a porous material. The supercritical fluids are used as a carrier for the bioactive agents described. Once the bioactive agents are carried to the medical device surface, they are sequestered there, preferably in the pores. The supercritical fluid is sprayed onto the medical devices achieving precipitation of the fluid. If appropriate conditions are used in the area of precipitation, bioactive agents can penetrate into the pores of the medical device before coming out of solution and expanding. | 10-29-2009 |
20090306756 | Hybrid Biodegradable/Non-Biodegradable Stent, Delivery System and Method of Treating a Vascular Condition - An intraluminal stent, an intraluminal stent delivery system, and a method of treating a vascular condition. The stent includes a framework composed of a biodegradable material. At least one strut is composed of a non-biodegradable material. The framework is operably attached to the at least one strut. The delivery system includes a catheter and a stent disposed on a portion of the catheter. The stent includes a framework composed of a biodegradable material. The stent further includes at least one strut composed of a non-biodegradable material. The framework is operably attached to the at least one strut. The method includes positioning an intraluminal stent via a catheter within a vessel. The stent includes at least one strut that is composed of a non-biodegradable material and is operably attached to a framework. The framework expands during deployment of the intraluminal stent. The framework is allowed to biodegrade within the vessel. | 12-10-2009 |
20100016950 | Streamlined Stents - A stent for implantation within the body of a patient is disclosed. The stent can be formed from one or more stent modules comprising a plurality of stent struts, one or more of which have an inner contour designed for streamlined fluid flow when the stent is implanted within an anatomical passageway of the patient. | 01-21-2010 |
20100125323 | Coil Stent Delivery System and Method of Use - The coil stent delivery system and method of use includes a stent delivery system including a coil stent; a housing, the housing having a receiver defining a receiver chamber and a sheath defining a sheath lumen, the receiver chamber being in communication with the sheath lumen; and a screw assembly, the screw assembly having a shaft, a helical screw disposed about a distal portion of the shaft, and a drive operably coupled to the shaft. The shaft is disposed in the receiver chamber and the sheath lumen, the helical screw is disposed in the sheath, and the coil stent is disposed about the shaft in the receiver chamber and engages the helical screw. Rotation of the drive moves the coil stent through the sheath lumen. | 05-20-2010 |
20100125325 | Stent With Cathodic Protection and Stent Delivery System - The stent with cathodic protection and stent delivery system includes a stent delivery system including a catheter; a balloon operably attached to the catheter; and a stent disposed on the balloon. The stent includes a stent body having a first stent layer of an anodic stent material disposed about a second stent layer of a cathodic stent material; and a battery having a first battery layer of an anodic battery material and a second battery layer of a cathodic battery material. The first stent layer is electrically coupled to the first battery layer and the second stent layer is electrically coupled to the second battery layer. | 05-20-2010 |
20100280595 | Method and Device for Localized Administration of Calcium Chelating Agent - A system for treating atherosclerotic cardiovascular disease and cardiac valve dysfunction comprises delivering one or more calcium chelating agents locally to a treatment site. One aspect of the invention provides a method including delivering a nano-particulate calcium chelating agent into a vascular wall. Another aspect of the invention provides a method and device for forming a sealed chamber around a cardiac valve, releasing one or more calcium chelating agents into the sealed chamber and decalcifying a cardiac valve in need thereof. | 11-04-2010 |
20100286758 | Implantable Temporary Flow Restrictor Device - An implantable flow restrictor plug is disclosed that is disposed within a deployed endoluminal prosthesis to initially restrict, then gradually restore blood flow through the prosthesis after an angioplasty procedure. Upon initial deployment, the plug has a tubular biodegradable body defining a blood flow lumen therethrough that is sized to effectively reduce the amount of blood flow exiting the prosthesis. An inner surface of the body erodes or biodegrades in vivo to enlarge the plug lumen, thereby gradually restoring blood flow through the prosthesis until blood flow is unimpeded through the prosthesis, i.e., blood flow through the vessel is fully restored. The flow restrictor plug may be attached to the endoluminal prosthesis to be delivered and deployed therewith, or may be formed within a previously deployed prosthesis. | 11-11-2010 |
20130090741 | Magnesium Alloys for Bioabsorbable Stent - A stent is formed from a magnesium alloy that consists essentially of: 0-10 weight % rare earth element; 0-5 weight % Li; 0-1 weight % Mn; 0-1 weight % Zr; and balance Mg, or the stent is formed from a magnesium alloy that consists essentially of: 0-5 weight % rare earth element; 0-8 weight % Li; 0-1 weight % Mn; 0-1 weight % Sn; 0-3 weight % Al; 0-4 weight % Zn; and balance Mg. | 04-11-2013 |
20130103161 | Iron Based Alloys for Bioabsorbable Stent - A stent includes an iron-based alloy that consists essentially of: Fe—X—Y, wherein X is at least one austenite stabilizing element selected from the group consisting of Co, Ni, Mn, Cu, Re, Rh, Ru, Ir, Pt, Pd, C, and N, and wherein Y is at least one corrosion-activator species selected from the group consisting of Au, and Pd. | 04-25-2013 |
20130284310 | APPARATUS AND METHODS FOR FILLING A DRUG ELUTING MEDICAL DEVICE VIA CAPILLARY ACTION - Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent. | 10-31-2013 |
20140213971 | NERVE IMPINGEMENT SYSTEMS INCLUDING AN INTRAVASCULAR PROSTHESIS AND AN EXTRAVASCULAR PROSTHESIS AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation assemblies ( | 07-31-2014 |