João Manuel
João Manuel Braz Goncalves, Montijo PT
| Patent application number | Description | Published |
|---|---|---|
| 20100136627 | Engineered Rabbit Antibody Variable Domains and Uses Thereof - The present invention relates to methods for screening and producing polypeptides that immunospecifically bind to an antigen, which: polypeptides comprise binding domains that are derived from rabbit immunoglobulin. Using rabbit antibody heavy-chain or light-chain scaffolds, the methods of the invention allow identification of novel CDR loops and framework regions that confer enhanced stability and/or affinity to isolated immunoglobulin variable domains, in particular, relative to those derived from rodent antibodies. The enhanced stability and/or affinity of the variable domains of the invention permit their use in the production research tools or therapeutic immunospecific polypeptides, including single domain immunospecific polypeptides, i.e., comprising one of a V | 06-03-2010 |
João Manuel Braz Goncalves, Montijo PT
| Patent application number | Description | Published |
|---|---|---|
| 20100136627 | Engineered Rabbit Antibody Variable Domains and Uses Thereof - The present invention relates to methods for screening and producing polypeptides that immunospecifically bind to an antigen, which: polypeptides comprise binding domains that are derived from rabbit immunoglobulin. Using rabbit antibody heavy-chain or light-chain scaffolds, the methods of the invention allow identification of novel CDR loops and framework regions that confer enhanced stability and/or affinity to isolated immunoglobulin variable domains, in particular, relative to those derived from rodent antibodies. The enhanced stability and/or affinity of the variable domains of the invention permit their use in the production research tools or therapeutic immunospecific polypeptides, including single domain immunospecific polypeptides, i.e., comprising one of a V | 06-03-2010 |
João Manuel Calado Da Silva, Aljustrel PT
| Patent application number | Description | Published |
|---|---|---|
| 20110129670 | NANOMETRIC-SIZED CERAMIC MATERIALS, PROCESS FOR THEIR SYNTHESIS AND USES THEREOF - The disclosed subject concerns nanometric-sized ceramic materials in the form of multiple crystalline structures, composites, or solid solutions, the process for their synthesis, and uses thereof. These materials are mainly obtained by detonation of two water-in-oil (W/O) emulsions, one of which is prepared with precursors in order to present a detonation regime with temperature lower than 2000° C., and they present a high chemical and crystalline phase homogeneity, individually for each particle, as well as a set of complementary properties adjustable according to the final applications, such as a homogeneous distribution of the primary particles, very high chemical purity level, crystallite size below 50 nm, surface areas by mass unit between 25 and 500 m2/g, and true particle densities higher than 98% of the theoretical density. This set of characteristics makes this materials particularly suitable for a vast range of applications in the nanotechnology field, such as, for example, nanocoatings, magnetic nanofluids, nanocatalysts, nanosensors, nanopigments, nanoadditives, ultra light nanocomposites, drug release nanoparticles, nanomarkers, nanometric films, etc. | 06-02-2011 |
| 20110183833 | CERAMIC POWDERS COATED WITH A NANOPARTICLE LAYER AND PROCESS FOR OBTAINING THEREOF - The disclosed subject matter relates to ceramic powders coated with a layer of nanoparticles of multiple crystalline structures and processes for obtaining the same. These coatings can be obtained by means of the introduction of precursors in water in oil emulsions, which upon decomposition during its detonation, form the nanoparticles that adhere to the surface of the ceramic powder intended to coat. The later base ceramic powder can be synthesized during the emulsion detonation (W/O) or simply be directly placed in its composition. The properties of the obtained coating, such as thickness, adhesion, porosity and coated surface percentage, can be adjusted according to the application desired. The ceramic powders coated can applicable to several types of areas of nanotechnology, such as electronics, biomedicine, chemistry, ceramics, energy industries, and the like. | 07-28-2011 |
| 20130224488 | PROCESS FOR NANOMATERIAL SYNTHESIS FROM THE PREPARATION AND DETONATION OF AN EMULSION, PRODUCTS AND EMULSIONS THEREOF - The present invention refers to a nanomaterial synthesis process from the decomposition and subsequent reaction among common and economical insoluble precursors, or precursors which hydrolyze in contact with water, which are incorporated in the internal phase of an emulsion. These insoluble precursors are introduced in the internal phase of an emulsion, then being subject to decomposition and subsequent reaction in the solid state, under shockwave effect during the detonation of the emulsion, the nanomaterial with the intended structure being in the end obtained. The process of the present invention therefore allows obtaining a wide range of nanomaterial as composites or binary, ternary structures or higher structures, with small-sized homogenous primary particles, applicable to several technological fields. | 08-29-2013 |
| 20130251623 | CONTINUOUS PROCESS FOR NANOMATERIAL SYNTHESIS FROM SIMULTANEOUS EMULSIFICATION AND DETONATION OF AN EMULSION - The present invention refers to a continuous process for in secco nanomaterial synthesis from the emulsification and detonation of an emulsion. The said process combines the simultaneous emulsification and detonation operations of the emulsion, thus assuring a production yield superior to 100 kg/h. When guaranteeing that the sensitization of the emulsion occurs mainly upon its feeding into the reactor, it is possible to avoid the accumulation of any class-1 substances along the entire synthesis process, thus turning it into an intrinsically safe process. Afterwards, dry collection of the nanomaterial avoids the production of liquid effluents, which are very difficult to process. Given that there's neither accumulation nor resort to explosive substances along the respective stages, the process of the present invention becomes a safe way of obtaining nanomaterial, thus allowing it to be implemented in areas wherein processes with hazardous substance aid are not allowed. | 09-26-2013 |
João Manuel De Castro Afonso, Cascais PT
| Patent application number | Description | Published |
|---|---|---|
| 20120192070 | INTERACTIVE SOUND SYSTEM - An interactive sound system is provided. The interactive sound system includes a plurality of sound channels arranged in a hierarchy, a representation of real space, a visual arrangement of the plurality of sound channels over the representation of real space, a user interface for simultaneous management of more than one sound channel in parallel, and a processing module. The processing module is configured to apply a user-attributed behavior to a sound channel over a hierarchically transmitted behavior, automatically assign a behavior to a sound channel following the activation of an automatic trigger, accept a manual assignment of a behavior to a sound channel following the activation of a human-operated trigger, and override a sound channel with an alarm behavior. | 07-26-2012 |
João Manuel Machado Pinto Germano, Lisbon PT
| Patent application number | Description | Published |
|---|---|---|
| 20130119293 | TRANSLUCENT LIGHTWEIGHT CONCRETE - The invention presented here belongs to the technical field of building materials, decorative materials and materials for furniture. It is intended to solve the problem of innovative uses with new solutions for the application of traditional building materials such as concrete. Its primary application is for materials used in building walls, floors, furniture and others within their technical field. Its main features, the translucency and lightness, result from the incorporation of fiber optics and granulated cork in the composition at the time of mixing with the special mortar cement. After setting we obtain a new material of resistance similar to traditional concrete, weighing less and with a certain degree of translucency. Changing the traditional formulation of concrete through the introduction of these two materials, alters the physical properties of the resulting compound. | 05-16-2013 |
João Manuel Pinto Filipe, Almere NL
| Patent application number | Description | Published |
|---|---|---|
| 20100198861 | METHOD AND SYSTEM FOR PROCESSING MEASURMENT DATA FOR WEBSITE STATISTICS - A method and a system for processing measurement data for website statistics are provided. The measurement data is processed in parallel bucket writers and stored in buckets. Upon receiving a report request the buckets are processed in parallel bucket queriers to obtain report data. | 08-05-2010 |
João Manuel Pinto Filipe, Almere NL
| Patent application number | Description | Published |
|---|---|---|
| 20100198861 | METHOD AND SYSTEM FOR PROCESSING MEASURMENT DATA FOR WEBSITE STATISTICS - A method and a system for processing measurement data for website statistics are provided. The measurement data is processed in parallel bucket writers and stored in buckets. Upon receiving a report request the buckets are processed in parallel bucket queriers to obtain report data. | 08-05-2010 |
João Manuel Ribeiro Da Silva Tavares, Porto PT
| Patent application number | Description | Published |
|---|---|---|
| 20110152621 | DEVICE FOR MEASURING AND ANALYSING THE COLOUR OF THE OUTER EAR AND EAR CANAL - The present application concerns a device for measurement and analysis of the middle ear and ear channel colour for the diagnosis of ear infections. The device is composed of a otoscope ( | 06-23-2011 |