Patent application number | Description | Published |
20090156912 | IMPLANTABLE OPTICAL SENSOR AND METHOD FOR MANUFACTURE - An implantable optical sensor and associated manufacturing method include a sensor housing having an inner surface and an outer surface and a window formed in the housing extending between the housing inner surface and the housing outer surface. An opto-electronic device enclosed within the housing and having a photonic surface is operatively positioned proximate the window for emitting light through the window or detecting light through the window. An optical coupling member is positioned between the opto-electronic device and the window for reducing light reflection at a surface within the implantable optical sensor. | 06-18-2009 |
20090156918 | IMPLANTABLE OPTICAL SENSOR AND METHOD FOR USE - An implantable medical device includes a hermetically sealed housing and a first light emitting diode (LED) enclosed within the housing configured to detect light corresponding to a selected light wavelength. A conductive element extends from the LED for carrying a current signal corresponding to the light detected by the LED, the intensity of the detected light being correlated to a change in a physiological condition in a body fluid volume or a tissue volume proximate the LED. | 06-18-2009 |
20090270953 | Optical Device - A reflectance-type optical sensor includes one or more photodiodes formed in a semiconductor substrate. A well having sidewalls and a bottom is formed in the top surface of the substrate, and a reflective layer is formed on the sidewalls and bottom. A light-emitting diode (LED) is mounted in the well, so that light emitted laterally and rearwardly from the LED strikes the sidewalls or bottom and is redirected in a direction generally perpendicular to the top surface of the substrate. The optical sensor can be fabricated using microelectromechanical systems (MEMS) fabrication techniques. | 10-29-2009 |
20100030043 | IMPLANTABLE MEDICAL SYSTEM INCLUDING MULTIPLE SENSING MODULES - A medical system includes at least two sensing modules that each generate an optical signal that changes as a function of a physiological parameter of a patient. The sensing modules may be coupled to a common light source and a common receiver via an optically transmissive member. At least a first sensing module that is closest to the light source along a length of the optically transmissive member may include a waveguide to split the light emitted by the light source. A first portion of the light may be directed toward the first sensing module and a second portion of the light may be directed toward a second sensing module that is placed downstream of the first sensing module in a direction substantially along the direction of light flow through the optically transmissive member and away from the light source. | 02-04-2010 |
20100185262 | CO-LOCATION OF EMITTERS AND DETECTORS AND METHOD OF OPERATION - An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test | 07-22-2010 |
20100317937 | Device and Method for Monitoring of Absolute Oxygen Saturation and Total Hemoglobin Concentration - A medical device for monitoring of oxygen saturation includes an optical sensor adapted for positioning adjacent to a tissue volume. The optical sensor has a light emitting portion capable of emitting light at a plurality of wavelengths and a light detecting portion capable of generating an electrical output signal corresponding to light incident on the detecting portion. A control module coupled to the optical sensor controls the light emitted by the light emitting portion. A monitoring module receives the output signal from the light detecting portion and computes a volume-independent measure of oxygen saturation in the volume of tissue using the output signal. | 12-16-2010 |
20100317938 | Device and Method for Monitoring of Absolute Oxygen Saturation and Tissue Hemoglobin Concentration - A method and medical device for detecting signals that detects emitted light scattered by a volume of tissue delivered along a first pathway at a plurality of wavelengths to generate corresponding first detected light intensity output signals, detects emitted light scattered by the volume of tissue delivered along a second pathway different from the first pathway at a plurality of wavelengths to generate corresponding second detected light intensity output signals, determines whether a difference between the emitted light detected along the first pathway and the emitted light detected along the second pathway is greater than a predetermined threshold, and alters sensing by the device in response to the determining whether a difference is greater than the predetermined threshold. | 12-16-2010 |
20100317939 | Device and Method for Monitoring of Absolute Oxygen Saturation and Tissue Hemoglobin Concentration - A method and medical device for detecting signals that detects emitted light scattered by a volume of tissue delivered along a first pathway and a second pathway different from the first pathway, detects emitted light scattered by a volume of tissue delivered along a third pathway and a fourth pathway different from the third pathway, determines a first uniformity corresponding to the emitted light detected along the first pathway and the second pathway, determines a second uniformity corresponding to the emitted light detected along third pathway and the fourth pathway, determines a total uniformity in response to the determined first uniformity and the determined second uniformity, and alters sensing by the device in response to the determined total uniformity. | 12-16-2010 |
20100317940 | Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction - A medical device for monitoring a patient condition includes a sensor capable of being advanced transvascularly to be positioned along a volume of tissue, the sensor including a first combination of a light source and a light detector to emit light into a volume of tissue and to detect light scattered by the volume of tissue and to generate a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal and compute a measure of tissue oxygenation using the light detector output signal. | 12-16-2010 |
20100317941 | ABSOLUTE CALIBRATED TISSUE OXYGEN SATURATION AND TOTAL HEMOGLOBIN VOLUME FRACTION - A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation. | 12-16-2010 |
20100317942 | Tissue Oxygenation Monitoring in Heart Failure - A medical device system and associated method are used for monitoring a heart failure patient. A medical device for monitoring delivery of a therapy includes a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient, a therapy delivery module to deliver a therapy, and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement. | 12-16-2010 |
20100317943 | Active Noise Cancellation in an Optical Sensor Signal - A medical device system and associated method are used for monitoring tissue oxygenation. An optical sensor produces a signal corresponding to tissue light attenuation. A processor receives the optical sensor signal and computes a first measure of light attenuation at a first light wavelength and a second measure of light attenuation at a second light wavelength. In one embodiment, noise cancellation circuitry receives the first measure and the second measure and generates a guessed ratio of the first and second measures. Using the first measure, the second measure and the guessed ratio, the noise cancellation circuitry provides a peak output power when the guessed ratio corresponds to an actual ratio of the first and second measures. | 12-16-2010 |
20100317946 | Shock Reduction Using Absolute Calibrated Tissue Oxygen Saturation and Total Hemoglobin Volume Fraction - An implantable medical device for detecting and treating an arrhythmia includes an optical sensor adapted for positioning adjacent to a blood-perfused tissue volume. In one embodiment for controlling arrhythmia therapies delivered by the device, the optical sensor is controlled to emit light in response to detecting an arrhythmia, detect light scattered by the volume of blood perfused tissue including measuring an optical sensor output signal corresponding to the intensity of scattered light for at least four spaced-apart wavelengths, and compute a volume-independent measure of tissue oxygen saturation from the detected light. The hemodynamic status of the arrhythmia is detected in response to the measure of tissue oxygen saturation. | 12-16-2010 |
20100317947 | Tissue Oxygenation Monitoring in Heart Failure - A medical device system and associated method control the delivery of a therapy to a patient. The system includes an activity sensor and detects a change in activity level of the patient. The system further include an optical sensor to sense signal corresponding to tissue light attenuation. The system computes a tissue oxygenation measurement in response to detecting a change in activity level. A parameter controlling delivery of the therapy is adjusted in response to detecting the decreased tissue oxygenation. | 12-16-2010 |
20100318146 | Tissue Oxygenation Monitoring in Heart Failure - A medical device for monitoring delivery of a therapy that includes a therapy delivery module to deliver a therapy, a controller to set a therapy delivery control parameter, an optical sensor to produce a signal corresponding to tissue light attenuation, and a processor configured to compute a tissue oxygenation measurement from the optical sensor signal, wherein the controller, the optical sensor, and the processor operate cooperatively to determine a setting of the therapy delivery control parameter corresponding to a maximum tissue oxygenation. | 12-16-2010 |
20100318149 | Shock Reduction Using Absolute Calibrated Tissue Oxygen Saturation and Total Hemoglobin Volume Fraction - An implantable medical device that includes an optical sensor for providing a signal corresponding to light attenuation by a volume of blood perfused tissue, a control module coupled to the optical sensor controlling the light emitted by the optical sensor, a monitoring module receiving an optical sensor output signal and measuring light attenuation, a tissue electrode for stimulating the volume of blood perfused tissue, a pulse generator coupled to the tissue electrode for delivering electrical stimulation to the volume of blood-perfused tissue, and a processor coupled to the cardiac electrode and the monitoring module and configured to detect an arrhythmia in response to the depolarization signals, compute a tissue oxygenation measurement and control the pulse generator to deliver electrical stimulation to the volume of blood-perfused tissue in response to detecting the arrhythmia, and detect a hemodynamic status of the arrhythmia in response to at least one of a detected rate of tissue oxygenation decline and a detected rate of tissue oxygenation recovery. | 12-16-2010 |
20110066017 | METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module controls the light emission so that an emitted light intensity at each of the plurality of wavelengths is within a predetermined intensity range, and determines a tissue oxygenation index in response to only the detected light intensity output signals, and a therapy delivery module delivers therapy in response to the determined tissue oxygenation index. | 03-17-2011 |
20110066018 | METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and apparatus for controlling delivery of therapy that includes an emitting portion emitting light at a predetermined emitted light intensity to a volume of tissue at a plurality of wavelengths, and a detecting portion detecting the emitted light scattered by the volume of tissue to generate corresponding detected light intensity output signals. A control module adjusts the detected light intensity output signals for shifts in intensity corresponding to the emitted light intensity, and determines a tissue oxygenation index in response to only the adjusted detected light intensity output signals, and a therapy delivery module controlling therapy in response to the determined tissue oxygenation index. | 03-17-2011 |
20110066198 | METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a therapy delivery module coupled to the electrode to deliver a therapy via the electrode in response to the sensed cardiac signals, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the optical sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, and determine whether the delivered therapy restored cardiac hemodynamic function in response to the determined tissue oxygenation trend. | 03-17-2011 |
20110066204 | METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a therapy delivery module coupled to the electrode to deliver a therapy via the electrode in response to the sensed cardiac signals, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy; and a controller coupled to the therapy delivery module and the sensor, the controller configured to determine a tissue oxygenation measurement in response to the output signal, and determine whether the delivered therapy was successful in restoring cardiac hemodynamic function in response to the tissue oxygenation measurement. | 03-17-2011 |
20110066206 | METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS - A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a monitoring module detecting a cardiac event in response to the sensed cardiac signals using first detection criteria, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the monitoring module, the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, determine a recovery index in response to the determined tissue oxygenation trend, and control one or both of detecting a cardiac event by the monitoring module and delivery of therapy by the therapy delivery module in response to the determined recovery index. | 03-17-2011 |
20110190608 | OPTICAL SENSOR FOR MEDICAL DEVICE - An optical sensor for a medical device includes a fixed lens spacing between emit and receive modules to achieve target sensor sensitivity, while varying other sensor parameters in order to increase signal amplitude without increasing power demand. The size of at least one of emit and receive module lenses of an optical sensor, and the offset between the opto-electronic component and the respective lens of at least one of emit and receive modules is decreased to increase amplitude of the signal received by the receive module from the emit module. | 08-04-2011 |
20110190609 | OPTICAL SENSOR FOR MEDICAL DEVICE - An optical sensor for a medical device includes a fixed lens spacing between emit and receive modules to achieve target sensor sensitivity, while varying other sensor parameters in order to increase signal amplitude without increasing power demand. An optical sensor connected to a housing of a medical device includes a circuit board, an opto-electronic component, a wall, a lens, and a ferrule. The circuit board is arranged within the housing. The opto-electronic component is mounted on a surface of the circuit board. The wall protrudes from the surface of the circuit board and surrounds the opto-electronic component. The lens is offset from the surface of the circuit board. The ferrule is connected to the housing, the lens and the wall. An inner surface of the wall mates with an outer surface of the ferrule. | 08-04-2011 |
20110190610 | OPTICAL SENSOR FOR MEDICAL DEVICE - An optical sensor for a medical device includes a fixed lens spacing between emit and receive modules to achieve target sensor sensitivity, while varying other sensor parameters in order to increase signal amplitude without increasing power demand. The arrangement of an opto-electronic component within an optical sensor receive module is improved by masking the receive module lens with an opaque member to create a masked lens leading edge that is aligned with a leading edge of the opto-electronic component. | 08-04-2011 |
20120108923 | SYMMETRICALLY PACKAGED OPTICAL SENSORS FOR IMPLANTABLE MEDICAL DEVICES - Implantable medical devices and methods include an optical sensor that includes at least two optical sensor portions. The light emitting devices of the optical sensor are distributed among the at least two optical sensor portions. | 05-03-2012 |
20120108925 | MONITORING OF TISSUE HEMOGLOBIN CONCENTRATION - A medical device system and associated method monitor tissue hemoglobin concentration. Light attenuation is measured in a volume of tissue in a patient. A value of a tissue scattering coefficient corresponding to the tissue volume in the patient is established in response to the attenuation measurement. A second derivative of the light attenuation measurement is determined. An artifact correction term is computed in response to the established tissue scattering coefficient, and a tissue hemoglobin concentration is computed using the artifact correction term and the second derivative. | 05-03-2012 |
20120130208 | COEFFICENT DETERMINATION FOR BLOOD OXYGEN SATURATION AND TOTAL HEMOGLOBIN CONCENTRATION INDICES - A first concentration of a chromophore corresponding to a measurement volume of an optical sensor is determined. A second concentration of the chromophore is obtained in the vicinity of the measurement volume corresponding to a change in at least one of a total concentration of the chromophore and a relative concentration of a first form of the chromophore to the total concentration of the chromophore in the measurement volume. Light remittance measurements including a first light wavelength and a second light wavelength are obtained corresponding to the first chromophore concentration and the second chromophore concentration. A coefficient for computing an index of a change in the chromophore concentration is computed using the difference between the first and second chromophore concentrations and the first and second light remittance measurements. | 05-24-2012 |
20120245489 | Moment Fraction Computation for Sensors - An implantable medical sensor system provides signals representative of a magnitude of moment fraction applied to a sensor module at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A moment fraction is computed in response to the first signal and the second signal. In various embodiments, the moment fraction is used to guide positioning of the sensor module, indicate a need for repositioning the sensor module, report loading of the sensor module during normal operation for use as sensor design information and in setting sensor calibration ranges. | 09-27-2012 |
20120245864 | STRAIN COMPENSATION FOR PRESSURE SENSORS - A pressure sensing system provides signals representative of a magnitude of pressure at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A calculated pressure, a bending pressure error and a bend-compensated pressure are computed in response to the first signal and the second signal. | 09-27-2012 |
20130109938 | METHOD AND APPARATUS FOR CALIBRATING AN ABSOLUTE OXYGEN SATURATION SENSOR | 05-02-2013 |
20140107440 | DEVICE AND METHOD FOR MONITORING OF ABSOLUTE OXYGEN SATURATION AND TISSUE HEMOGLOBIN CONCENTRATION - A method and medical device for detecting signals that detects emitted light scattered by a volume of tissue delivered along a first pathway at a plurality of wavelengths to generate corresponding first detected light intensity output signals, detects emitted light scattered by the volume of tissue delivered along a second pathway different from the first pathway at a plurality of wavelengths to generate corresponding second detected light intensity output signals, determines whether a difference between the emitted light detected along the first pathway and the emitted light detected along the second pathway is greater than a predetermined threshold, and alters sensing by the device in response to the determining whether a difference is greater than the predetermined threshold. | 04-17-2014 |