| Patent application number | Description | Published |
|---|
| 20110247743 | AUTOMATED BIAS-PLY PREPARATION DEVICE AND PROCESS - A material preparation device is provided. The material preparation device includes a bias-ply assembly, a feedstock assembly and an application head. The bias-ply assembly is configured to pass a bias-ply backing material along a first path. The feedstock assembly is configured to pass a feedstock along a second path that crosses the first path at a select angle. The feedstock includes resin pre-impregnated fiber reinforced material (pre-preg) having the fibers at a first orientation relative to an edge of the feedstock. The application head is configured to transfer the pre-preg from the feedstock to the bias-ply backing material at a location where the first path crosses the second path to form a bias-ply with the fibers of the pre-preg having a second different orientation relative to an edge of the formed bias-ply. | 10-13-2011 |
| 20140259630 | Cutting Mechanism - There is disclosed a cutting mechanism | 09-18-2014 |
| 20140260858 | Composite Material Lay-up Equipment - There is disclosed composite material lay-up equipment | 09-18-2014 |
| 20150273773 | Composite Material Lay-up Equipment - There is disclosed composite material lay-up equipment for applying a plurality of individual lengths of elongate fibre reinforcement material to an article, the equipment comprising: a support head; a cutting mechanism carried by the support head for severing a plurality of individual lengths of elongate fibre reinforcement material. The cutting mechanism comprises a plurality of cutting elements coupled to and moveable with respect to the support head and a cassette removably attached to the support head and having a plurality of corresponding counteracting elements statically mounted thereto. Each cutting element is displaceable relative to the corresponding counteracting element to perform a cutting stroke in which the respective cutting and counteracting elements cooperate to sever a length of elongate fibre reinforcement material extending through the nip formed between them. | 10-01-2015 |
| 20150336336 | Cutting Mechanism - There is disclosed a cutting mechanism for severing elongate fibre reinforcement material in composite material lay-up equipment, the cutting mechanism comprising a cutting element and a counteracting element which cooperate to sever fibre reinforcement material extending through the nip between them, the cutting element being mounted on an elongate arm which is pivotable about a pivot axis A spaced from the nip, to displace the cutting element relatively to the counteracting element to perform a cutting stroke, the mechanism further comprising guide means arranged to guide the fibre reinforcement material through the nip in a feed direction transverse to the pivot axis A, and an actuation device for driving the elongate arm in a cutting stroke, the actuation device acting on the elongate arm at a position away from the cutting element. There is also provided composite material lay-up equipment comprising the cutting mechanism. | 11-26-2015 |
| Patent application number | Description | Published |
|---|
| 20160038056 | DETECTING TEMPERATURE SENSITIVITY OF A PATIENT'S AIRWAY - According to one embodiment of the present invention, an airflow perturbation device for detecting airway sensitivity to temperature comprises a pneumotachometer including a flow sensor to measure airflow through the apparatus; a perturbation mechanism to periodically alter air flow resistance in the apparatus; an air cooler; a pressure sensor to measure a difference in air pressure across the pneumotachometer and perturbation mechanism; and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor; and determine an airflow resistance based on the received data. Embodiments of the present invention further include a method for detecting airway sensitivity to temperature in substantially the same manners described above. | 02-11-2016 |
| 20160038057 | MEASURING RESPIRATORY MECHANICS PARAMETERS USING PERTURBATIONS - According to one embodiment of the present invention, a method of determining respiratory parameters comprises determining a ratio of pressure changes to flow changes induced in the breathing of a patient by an airflow perturbation device at each of a plurality of perturbation frequencies to form a dataset. Resistance, compliance, and inertance parameters of a model of a respiratory system are determined by comparing a predicted frequency dependence of the model to the dataset. Embodiments of the present invention further include a system and computer program product for determining respiratory parameters in substantially the same manners described above. | 02-11-2016 |
| 20160038697 | MEASURING RESPIRATORY MECHANICS PARAMETERS OF VENTILATED PATIENTS - An airflow perturbation device for measuring respiratory resistance of a patient breathing with the use of a ventilator comprises a sealed housing having a first port and a second port each configured to couple to a ventilator hose, a perturbation mechanism to periodically alter air flow resistance between the first port and the second port, a pneumotachometer comprising a flow sensor to measure airflow between the first port and the second port, a pressure sensor to measure a difference in air pressure between the first port and the second port, and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor. The computing system determines an airflow resistance based on the received data. Embodiments of the present invention further include a method and computer program product for measuring respiratory resistance of a ventilated patient in substantially the same manners described above. | 02-11-2016 |
| Patent application number | Description | Published |
|---|
| 20090116587 | METHOD, SYSTEM AND APPARATUS FOR GENERATING CONSTANT AMPLITUDE ZERO AUTOCORRELATION SEQUENCES - A method, system and apparatus for generating a constant amplitude zero autocorrelation (CAZAC) sequence to be transmitted on a wireless communication channel between a user equipment and a base station within a cellular communication network includes iteratively calculating elements of the CAZAC sequence according to a CAZAC sequence formula until a number of iterations has reached a predetermined iteration value determined in accordance with a number of subcarriers associated with the channel; obtaining a value of particular elements of the CAZAC sequence from a table of stored values at predetermined reset iteration values in order to limit error propagation; and generating the reference signal based upon the elements of the CAZAC sequence. The CAZAC sequence formula is one of a Chu sequence, Frank-Zadoff sequence, Zadoff-Chu (ZC) sequence, and Generalized Chirp-Like (GCL) Sequence. | 05-07-2009 |
| 20090300463 | SYSTEM AND METHOD FOR DETERMINING PARITY BIT SOFT INFORMATION AT A TURBO DECODER OUTPUT - A decoding circuit, is provided, comprising: a turbo decoder configured to receive a input systematic bit soft information values and input parity bit information values, and to generate output systematic bit soft information values and hard decoded bits according to a turbo decoding operation; and a parity bit soft information generation circuit configured to receive the input systematic bit soft information values, the input parity bit soft information values, and the output systematic bit soft information values; to determine initial forward metrics, initial backward metrics, and branch metrics as a function of the input parity bit soft information values and the output systematic bit soft information values; to determine output parity bit soft information values based on the branch metrics, the initial forward metrics, and the initial backward metrics; and to provide the output parity bit soft information values as a signal output. | 12-03-2009 |
| Patent application number | Description | Published |
|---|
| 20110059870 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 03-10-2011 |
| 20110203924 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 08-25-2011 |
| 20110269642 | MODULAR ASSAY PLATES, READER SYSTEMS AND METHODS FOR TEST MEASUREMENTS - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 11-03-2011 |
| 20120190590 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 07-26-2012 |
| 20120190591 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 07-26-2012 |
| 20130203620 | MODULAR ASSAY PLATES, READER SYSTEMS AND METHODS FOR TEST MEASUREMENTS - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 08-08-2013 |
| Patent application number | Description | Published |
|---|
| 20100028948 | METHODS OF ADMINISTERING/DOSING ANTI-RSV ANTIBODIES FOR PROPHYLAXIS AND TREATMENT - The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a RSV antigen, and methods using said compositions for detection or diagnosis a RSV infection. | 02-04-2010 |
| 20100189718 | MOLECULES WITH EXTENDED HALF-LIVES, COMPOSITIONS AND USES THEREOF - The present invention provides molecules, including IgGs, non-IgG immunoglobulins, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. | 07-29-2010 |
| 20100239574 | HIGH POTENCY RECOMBINANT ANTIBODIES AND METHOD FOR PRODUCING THEM - High potency antibodies, including immunologically active fragments thereof, having high kinetic association rate constants and optional high affinities are disclosed, along with methods for producing such antibodies. The high potency antibodies disclosed herein are of either the neutralizing or non-neutralizing type and have specificity for antigens displayed by microorganisms, especially viruses, as well as antigenic sites present on cancer cells and on various types of toxins, and the products of toxins. Processes for producing high potency neutralizing antibodies and increasing the potency of already existing neutralizing antibodies are also described. Methods of using said antibodies in the prevention and/or treatment of diseases, especially diseases induced or caused by viruses, are disclosed. | 09-23-2010 |
| 20100266614 | ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES - Ultra high affinity antibodies with binding affinities in the range of 10 | 10-21-2010 |
| 20120070447 | METHODS OF ADMINISTERING / DOSING ANTI-RSV ANTIBODIES FOR PROPHYLAXIS AND TREATMENT - The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a RSV antigen, and methods using said compositions for detection or diagnosis a RSV infection | 03-22-2012 |
| 20120135006 | ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES - Ultra high affinity antibodies with binding affinities in the range of 10 | 05-31-2012 |
| Patent application number | Description | Published |
|---|
| 20090104205 | Human-Murine Chimeric Antibodies Against Respiratory Syncytial Virus - This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection. | 04-23-2009 |
| 20110136689 | Dual Expression Vector System for Antibody Expression in Bacterial and Mammalian Cells - The present invention provides a dual expression vector, and methods for its use, for the expression and secretion of a full-length polypeptide of interest in eukaryotic cells, and a soluble domain or fragment of the polypeptide in bacteria. When expressed in bacteria, transcription from a bacterial promoter within a first intron and termination at the stop codon in a second intron results in expression of a fragment of the polypeptide, e.g., a Fab fragment, whereas in mammalian cells, splicing removes the bacterial regulatory sequences located in the two introns and generates the mammalian signal sequence, allowing expression of the full-length polypeptide, e.g., IgG heavy or light chain polypeptide. The dual expression vector system of the invention can be used to select and screen for new monoclonal antibodies, as well as to optimize monoclonal antibodies for binding to antigenic molecules of interest. | 06-09-2011 |
| 20120156195 | Human-Murine Chimeric Antibodies Against Respiratory Syncytial Virus - This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection. | 06-21-2012 |
| 20140093501 | Human-Murine Chimeric Antibodies Against Respiratory Syncytial Virus - This invention relates to a human antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, against respiratory syncytial virus which is MAb1129 and the use thereof for the prevention and/or treatment of RSV infection. | 04-03-2014 |
| Patent application number | Description | Published |
|---|
| 20100148288 | Vertical Cell Edge Junction Magnetoelectronic Device Family - Magnetoelectronic devices are fabricated by joining the edge of one ferromagnetic thin film element with the top, or bottom, portion of a second ferromagnetic, or nonmagnetic, thin film element. The devices also employ a new operational geometry in which the transport of bias current is in the film plane of at least one of the thin film elements, but is substantially perpendicular to the film plane of at least one of the thin film elements. Additionally, any of the variety magnetoelectronic devices (e.g., current-in-plane spin valves, current-perpendicular-to-the-plane spin valves, magnetic tunnel junctions, and lateral spin valves can be fabricated using these features. | 06-17-2010 |
| 20140176184 | Nonvolatile Logic Circuit Architecture & Method of Operation - Magnetoelectronic (ME) logic circuits and methods of operating the same are disclosed. Microsystems of different circuits made from different types of ME devices can be constructed and employed in applications such as sensors, smart dust, etc. | 06-26-2014 |
| 20150137200 | Hybrid Domain Wall-Hall Cross Device - A hybrid domain wall Hall cross device consists of a semiconductor Hall cross having a top surface and a pair of arms intersecting at a center region, and a ferromagnetic wire fabricated on the top surface, electrically isolated from the Hall cross, and having a constriction proximate to the center of the Hall cross. The device provides a magnetoelectronic MRAM storage cell with improved performance characteristics. Binary storage is associated with a trapped domain wall having one of two stable orientations. The bit state can be written using current driven domain wall motion. This is a STT process in which the write current is applied to a thin film, low impedance wire. Heating is minimized and no wear-out mechanism is known to exist. | 05-21-2015 |
| 20160020769 | Reconfigurable Magnetoelectronic Processing System - Magnetoelectronic (ME) logic circuits and methods of operating the same are disclosed for use in energy constrained applications in which logic operations are carried out using a minimal number of physical operations. Microsystems of different circuits made from different types of ME devices can be constructed and employed in applications such as sensors, smart dust, etc. including in clockless applications. | 01-21-2016 |
| Patent application number | Description | Published |
|---|
| 20100270444 | CABINET INSTALLATION ASSEMBLY - A cabinet installation system is characterized by the use of adjustable brackets and rails used to align a wall or base cabinet for mounting the cabinets on a wall. The brackets include horizontal and vertical legs which are connected via a hinge at one end and by an adjustable device at the other end so that the brackets have a triangular configuration. The adjustable device varies the angle between the legs so that when the vertical leg of a bracket is mounted on a wall, the horizontal leg can be adjusted to a level position. Front and rear rails are adjustably connected with the brackets. With the brackets arranged in spaced relation on a wall and the horizontal legs adjusted to level, the rails are adjusted relative to each bracket, respectively, so that the rails are linear, parallel and spaced according to the depth of the cabinet. When a cabinet is aligned relative to the rails, it can be secured to the wall in a straight and level position. | 10-28-2010 |
| 20100270445 | CABINET INSTALLATION ASSEMBLY - A cabinet installation system is characterized by the use of adjustable brackets and rails used to align a wall or base cabinet for mounting the cabinets on a wall. The brackets include horizontal and vertical legs which are connected together at one end and by an adjustable device at the other end so that the brackets have a triangular configuration. The adjustable device varies the angle between the legs so that when the vertical leg of a bracket is mounted on a wall, the horizontal leg can be adjusted to a level position. Front and rear rails are adjustably connected with the brackets. With the brackets arranged in spaced relation on a wall and the horizontal legs adjusted to level, the rails are adjusted relative to each bracket, respectively, so that the rails are linear, parallel and spaced according to the depth of the cabinet. When a cabinet is aligned relative to the rails, it can be secured to the wall in a straight and level position. | 10-28-2010 |
| Patent application number | Description | Published |
|---|
| 20080300167 | Patched genes and uses related thereto - Methods for isolating patched genes, including the mouse and human patched genes, as well as invertebrate patched genes and sequences, are provided. Decreased expression of patched is associated with the occurrence of human cancers, particularly basal cell carcinomas of the skin. The patched and hedgehog genes are useful in creating transgenic animal models for these human cancers. The patched nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as treatment of cancer, identification of cell type based on expression, and the like. The DNA is further used as a diagnostic for a genetic predisposition to cancer, and to identify specific cancers having mutations in this gene. | 12-04-2008 |
| 20100221724 | PATCHED POLYPEPTIDES AND USES RELATED THERETO - Methods for isolating patched genes, including the mouse and human patched genes, as well as invertebrate patched genes and sequences, are provided. Decreased expression of patched is associated with the occurrence of human cancers, particularly basal cell carcinomas of the skin. The patched and hedgehog genes are useful in creating transgenic animal models for these human cancers. The patched nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as treatment of cancer, identification of cell type based on expression, and the like. The DNA is further used as a diagnostic for a genetic predisposition to cancer, and to identify specific cancers having mutations in this gene. | 09-02-2010 |
| 20130029983 | AMINOTHIENOPYRIDAZINE INHIBITORS OF TAU ASSEMBLY - The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula I: | 01-31-2013 |
| Patent application number | Description | Published |
|---|
| 20090165032 | Method And Apparatus For Managing Broadcasting Services Using Broadcast Tokens - A method of managing radio broadcasting services includes: generating a broadcast token including information for associating a service with one or more subscriber groups, using the broadcast token to configure a transmission of the service by a broadcaster, and broadcasting the service to the subscriber group. At the broadcaster, the service can be configured by using parameters in the broadcast token to retrieve service content from a resource manager. | 06-25-2009 |
| 20090259925 | Broadcast Equipment Communication Protocol - A method for transmitting data between components of a digital broadcasting system includes: receiving payload data, adding a content layer header to the payload data to form a content layer data frame, adding a transmission and authentication layer header and a cyclic redundancy check field to the content layer data frame to form a transmission and authentication layer data frame, adding an application framing layer header to the transmission and authentication layer data frame to form an application framing layer data frame, and transmitting the application framing layer data frame to a destination component. | 10-15-2009 |
| 20100056043 | Radio Service Registry - A service registry for a radio broadcasting system includes a memory for storing information relating to services to be provided over the broadcasting system, a processor coupled to the memory, and a core interface for exchanging messages between the processor and a plurality of users, the processor being programmed to retrieve the information from the memory in response to the messages received on the interface, and to output the retrieved information to an importer. A method of broadcasting and a broadcasting system are also provided. | 03-04-2010 |
| 20100265398 | Systems and methods for transmitting media content via digital radio broadcast transmission for synchronized rendering by a receiver - Systems, methods, and processor readable media are disclosed for encoding and transmitting first media content and second media content using a digital radio broadcast system, such that the second media content can be rendered in synchronization with the first media content by a digital radio broadcast receiver. The disclosed systems, methods, and processor-readable media determine when a receiver will render audio and data content that is transmitted at a given time by the digital radio broadcast transmitter, and adjust the media content accordingly to provide synchronized rendering. In exemplary embodiments, these adjustments can be provided by: 1) inserting timing instructions specifying playback time in the secondary content based on calculated delays; or 2) controlling the timing of sending the primary or secondary content to the transmitter so that it will be rendered in synchronization by the receiver. | 10-21-2010 |
| 20110039492 | Digital radio broadcast receiver, broadcasting methods and methods for tagging content of interest - A digital radio broadcast system includes a processing system that receives first audio content, first program data identifying a first item for the first audio content, second audio content, and second program data identifying a second item for the second audio content such that a start of the first program data is received at the processing system within 0.5 seconds of a start of the first audio content. A digital radio broadcast signal including the audio content and the program data is processed for digital radio broadcast transmission via a transmitter. The processing system stops delivery of the first program data to the transmitter upon receipt of the second program data, the first program data thereby being truncated, and begins delivery of the second program data to the transmitter. A digital radio broadcast receiver can tag content of interest based on a user command registered at the receiver. | 02-17-2011 |
| 20120162512 | Systems and Methods for Transmitting Media Content via Digital Radio Broadcast Transmission for Synchronized Rendering by a Receiver - Systems, methods, and processor readable media are disclosed for encoding and transmitting first media content and second media content using a digital radio broadcast system, such that the second media content can be rendered in synchronization with the first media content by a digital radio broadcast receiver. The disclosed systems, methods, and processor-readable media determine when a receiver will render audio and data content that is transmitted at a given time by the digital radio broadcast transmitter, and adjust the media content accordingly to provide synchronized rendering. In exemplary embodiments, these adjustments can be provided by: 1) inserting timing instructions specifying playback time in the secondary content based on calculated delays; or 2) controlling the timing of sending the primary or secondary content to the transmitter so that it will be rendered in synchronization by the receiver. | 06-28-2012 |
| 20130265918 | BROADCAST EQUIPMENT COMMUNICATION PROTOCOL - A data link manager includes a User Datagram Protocol (UDP) receiver for receiving HD Radio broadcast equipment communication protocol (HDP) data or non-HD Radio broadcast equipment communication protocol (non-HDP) data using a User Datagram Protocol/Internet Protocol (UDP/IP) protocol; a Transmission Control Protocol (TCP) receiver; and a router for receiving data from the UDP receiver and the TCP receiver, for searching for a destination route in a routing table, and for forwarding the data received from the from the UDP receiver and the TCP receiver to an identified destination route. | 10-10-2013 |
