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| 20080214503 | Hiv Integrase Inhibitors - The present intention features compounds that are HIV integrase inhibitors and may be useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-04-2008 |
| 20080214527 | Hiv Integrase Inhibitors - The present invention features compounds that are HIV integrase inhibitors useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-04-2008 |
| 20080234231 | Hiv Integrase Inhibitors - The present invention features compounds that are HIV integrase inhibitors and may be useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-25-2008 |
| 20110003794 | Naphthyridine Integrase Inhibitors - The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 01-06-2011 |
| 20110152303 | Chemical Compounds - Novel diarylpyrimidine derivatives and pharmaceutically acceptable salts, solvates or hydrates thereof, designed to inhibit HIV reverse transcriptase, are provided, and a pharmaceutical composition containing the same, especially an anti-HIV agent. More specifically, novel diarylpyrimidine derivatives that are derivatives of the HIV reverse transcriptase inhibitor TMC278 of formula (1 | 06-23-2011 |
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| 20090318421 | Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity - The present invention is to provide a novel compound (I) shown below, having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. | 12-24-2009 |
| 20110183940 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 07-28-2011 |
| 20110190236 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 08-04-2011 |
| 20110263855 | PROCESSES AND INTERMEDIATES FOR CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS - Processes are provided which create an aldehyde methylene, or hydrated or hemiacetal methylene attached to a heteroatom of a 6 membered ring without going through an olefinic group and without the necessity of using an osmium reagent. In particular, a compound of formula (I) can be produced from (II) and avoid the use of an allyl amine: (formulae I and II) where R, P | 10-27-2011 |
| 20120115875 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY - The present invention is to provide a novel compound (I) shown below, having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. | 05-10-2012 |
| 20120209000 | CHEMICAL COMPOUNDS - The present invention is directed to a compound of the formula: | 08-16-2012 |
| 20130018049 | Azaindole Compounds and Methods for Treating HIV - Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV). | 01-17-2013 |
| 20130184263 | Derivatives of Betulin - The present invention relates to compounds characterized by having a structure according to the following Formula I: | 07-18-2013 |
| 20140031555 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 01-30-2014 |
| 20140039207 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 02-06-2014 |
| 20140094605 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound I-I yielding compound II-II: | 04-03-2014 |
| 20140243521 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-I1, whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. | 08-28-2014 |
| 20140256679 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-11-2014 |
| 20140256713 | 2-OXONAPHTHYRIDINE-3-CARBOXAMIDES HIV INTEGRASE INHIBITORS - The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-11-2014 |
| 20140256961 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-11-2014 |
| 20140343092 | Pyrrolopyridinone Compounds And Methods For Treating HIV - Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV). | 11-20-2014 |
| 20140350032 | PROPENOATE DERIVATIVES OF BETULIN - The present invention relates to a compound characterized by the following Formula I: | 11-27-2014 |
| 20140357643 | Derivatives of Betulin - The present invention relates to compounds characterized by having a structure according to the following Formula I: | 12-04-2014 |
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| 20120230177 | CONGESTION ABATEMENT IN A NETWORK INTERCONNECT - A method and system for detecting congestion in a network of nodes, abating the network congestion, and identifying the cause of the network congestion is provided. A congestion detection system may comprise a detection system, an abatement system, and a causation system. The detection system monitors the performance of network components such as the network interface controllers and tiles of routers to determine whether the network is congested such that a delay in delivering packets becomes unacceptable. Upon detecting that the network is congested, an abatement system abates the congestion by limiting the rate at which packets are injected into the network from the nodes. Upon detecting that the network is congested, a causation system may identify the job that is executing on a node that is the cause of the network congestion. | 09-13-2012 |
| 20120230188 | CONGESTION CAUSATION IN A NETWORK INTERCONNECT - A method and system for detecting congestion in a network of nodes, abating the network congestion, and identifying the cause of the network congestion is provided. A congestion detection system may comprise a detection system, an abatement system, and a causation system. The detection system monitors the performance of network components such as the network interface controllers and tiles of routers to determine whether the network is congested such that a delay in delivering packets becomes unacceptable. Upon detecting that the network is congested, an abatement system abates the congestion by limiting the rate at which packets are injected into the network from the nodes. Upon detecting that the network is congested, a causation system may identify the job that is executing on a node that is the cause of the network congestion. | 09-13-2012 |
| 20120230212 | CONGESTION DETECTION IN A NETWORK INTERCONNECT - A method and system for detecting congestion in a network of nodes, abating the network congestion, and identifying the cause of the network congestion is provided. A congestion detection system may comprise a detection system, an abatement system, and a causation system. The detection system monitors the performance of network components such as the network interface controllers and tiles of routers to determine whether the network is congested such that a delay in delivering packets becomes unacceptable. Upon detecting that the network is congested, an abatement system abates the congestion by limiting the rate at which packets are injected into the network from the nodes. Upon detecting that the network is congested, a causation system may identify the job that is executing on a node that is the cause of the network congestion. | 09-13-2012 |
| 20120287777 | DYNAMICALLY UPDATING ROUTING INFORMATION WHILE AVOIDING DEADLOCKS AND PRESERVING PACKET ORDER AFTER A LINK ERROR - A system for allowing dynamic changing of routing information of a network interconnect while avoiding deadlocks and preserving packet ordering. A network resiliency system detects when an error in the network interconnect occurs and dynamically generates new routing information for the routers that factors in the detected error. The network resiliency system then generates new routing information that factors in the failure. The network resiliency system then directs the network interconnect to enter a quiescent state in which no packets are transiting through the network interconnect. After the network interconnect enters the quiescent state, the network resiliency system directs the loading of the new routing information into the routing tables of the network interconnect and then directs the network interconnect to start injecting request packets into the network interconnect. | 11-15-2012 |
| 20120287821 | DYNAMICALLY UPDATING ROUTING INFORMATION WHILE AVOIDING DEADLOCKS AND PRESERVING PACKET ORDER AFTER A CONFIGURATION CHANGE - A system for allowing dynamic changing of routing information of a network interconnect while avoiding deadlocks and preserving packet ordering. A network resiliency system detects when an error in the network interconnect occurs and dynamically generates new routing information for the routers that factors in the detected error. The network resiliency system then generates new routing information that factors in the failure. The network resiliency system then directs the network interconnect to enter a quiescent state in which no packets are transiting through the network interconnect. After the network interconnect enters the quiescent state, the network resiliency system directs the loading of the new routing information into the routing tables of the network interconnect and then directs the network interconnect to start injecting request packets into the network interconnect. | 11-15-2012 |
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| 20090281194 | Combinations for treating HIV-associated pain - The present invention relates to novel combinations suitable for the treatment or amelioration of pain of various genesis or aetiology, which comprise, as active ingredients, at least one cannabinoid receptor binding compound, in particular a cannabinoid receptor binding naphthalene derivative, and at least one opioid, to their preparation, to their use as medicaments and to medicaments comprising them. | 11-12-2009 |
| 20100041641 | USES OF METABOTROPIC GLUTAMATE RECEPTORS - The invention concerns the use an mGluR modulator, e.g. an mGluR5 modulator, for the treatment, prevention or delay of progression of cognitive dysfunction. | 02-18-2010 |
| 20110212980 | COMBINATIONS FOR THE TREATMENT OF MIGRAINE - The present invention relates to novel combinations suitable for the treatment of migraine of various genesis or aetiology, which comprise, as active ingredients, at least one 5-HT | 09-01-2011 |
| 20120172346 | USE OF NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA 7 ACTIVATORS - The invention concerns the use of a nicotinic acetylcholine receptor alpha 7 activators for the treatment, prevention or delay of progression of dyskinesia associated with dopamine agonist therapy in Parkinson's Disease. | 07-05-2012 |
| 20120309742 | USE OF METABOTROPIC GLUTAMATE RECEPTORS - The invention concerns the use an mGluR modulator, e.g. an mGluR5 modulator, for the treatment, prevention or delay of progression of cognitive dysfunction. | 12-06-2012 |
| 20130090346 | Use of 1H-quinazoline-2,4-diones - The invention concerns the use of competitive AMPA receptor antagonists for the treatment or prevention of photosensitive epilepsy. | 04-11-2013 |
| 20140163050 | Use of 1H-quinazoline-2,4-diones - The invention concerns the use of competitive AMPA receptor antagonists for the treatment or prevention of photosensitive epilepsy. | 06-12-2014 |
| 20140187600 | USE OF METABOTROPIC GLUTAMATE RECEPTORS - The invention concerns the use an mGluR modulator, e.g. an mGluR5 modulator, for the treatment, prevention or delay of progression of cognitive dysfunction. | 07-03-2014 |
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| 20100103230 | MULTI-COLOR INK TANK WITH ELEMENTS ENABLING COMPATIBILITY WITH A SUPPORT STRUCTURE FOR INDIVIDUAL DIFFERENT COLOR IN TANKS - A multi-color ink tank is adapted to replace individual different color ink tanks in a cavity of a given support structure. Elements on the body of the multi-color ink tank have configurations enabling compatibility with the support structure. The elements include empty opposite side portions of the body defining laterally spaced apart bottom openings that adapt the opposite side portions to seat in spaced slots in the cavity over keys therein and an intermediate central recessed region defined between the opposite side portions that adapts the body to straddle an intermediate slot between the spaced slots and a key therein and also straddle partitions in the cavity forming the slots. The elements also include tabs blocking some latches used to releasably lock some individual ink tanks to thereby identify the latch to be used to releasably lock the multi-color ink tank. | 04-29-2010 |
| 20100157004 | Multi-Color Ink Tank With Features Spaced by Distances Ensuring Interface with Printhead and Carrier Support Structure - A multi-color ink tank includes certain features that properly interface with features on a printhead and carrier support structure to operatively seat the ink tank in the carrier support structure in a sealed flow communicative relationship with the printhead. These interface features are spaced apart relative to one another at distances (or dimensions) that ensure the desired seating and sealing of the ink tank in the carrier support structure and thereby the reliable supply of ink for operation of the inkjet printing system. | 06-24-2010 |
| 20100165060 | Individual Ink Tank with Features Spaced by Distances Ensuring Interface with Printhead and Carrier Support Structure - A individual ink tank includes certain features that properly interface with features on a printhead and carrier support structure to operatively seat the ink tank in the carrier support structure in a sealed flow communicative relationship with the printhead. These interface features are spaced apart relative to one another at distances (or dimensions) that ensure the desired seating and sealing of the ink tank in the carrier support structure and thereby the reliable supply of ink for operation of the inkjet printing system. | 07-01-2010 |
| 20100165061 | Mono Ink Tank with Features Spaced by Distances Ensuring Interface with Printhead and Carrier Support Structure - A mono ink tank includes certain features that properly interface with features on a printhead and carrier support structure to operatively seat the ink tank in the carrier support structure in a sealed flow communicative relationship with the printhead. These interface features are spaced apart relative to one another at distances (or dimensions) that ensure the desired seating and sealing of the ink tank in the carrier support structure and thereby the reliable supply of ink for operation of the inkjet printing system. | 07-01-2010 |
| 20110032313 | INDIVIDUAL INK TANK WITH FEATURES SPACED BY DISTANCES ENSURING INTERFACE WITH PRINTHEAD - A individual ink tank includes certain features that properly interface with features on a printhead to operatively seat the ink tank in the printhead in a sealed flow communicative relationship with the printhead. These interface features are spaced apart relative to one another at distances (or dimensions) that ensure the desired seating and sealing of the ink tank in the printhead and thereby the reliable supply of ink for operation of the inkjet printing system. | 02-10-2011 |
| 20110032316 | MONO INK TANK WITH FEATURES SPACED BY DISTANCES ENSURING INTERFACE WITH PRINTHEAD - A mono ink tank includes certain features that properly interface with features on a printhead to operatively seat the ink tank in the printhead in a sealed flow communicative relationship with the printhead. These interface features are spaced apart relative to one another at distances (or dimensions) that ensure the desired seating and sealing of the ink tank in the printhead and thereby the reliable supply of ink for operation of the inkjet printing system. | 02-10-2011 |
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| 20110174544 | Bearing Assemblies, Bearing Apparatuses Using the Same, and Related Methods - Various embodiments relate to bearing assemblies configured to enable removal and replacement of superhard bearing elements, and bearing apparatuses that may utilize such bearing assemblies. The disclosed bearing assemblies may be used in a number of applications, such as downhole motors in subterranean drilling systems, directional drilling systems, roller-cone drill bits, and many other applications. In an embodiment, a bearing assembly includes a support ring and a retention ring assembled with the support ring. The retention ring includes a plurality of through holes. The bearing assembly further includes a plurality of superhard bearing elements, with each superhard bearing element inserted partially through and projecting from a corresponding one of the through holes of the retention ring. The retention ring and each superhard bearing element are collectively configured to restrict displacement of each superhard bearing element beyond a selected position in a direction away from the support ring. | 07-21-2011 |
| 20130186691 | BEARING ASSEMBLIES, AND BEARING APPARATUSES USING THE SAME - Various embodiments relate to bearing assemblies configured to enable removal and replacement of superhard bearing elements, and bearing apparatuses that may utilize such bearing assemblies. The disclosed bearing assemblies may be used in a number of applications, such as downhole motors in subterranean drilling systems, directional drilling systems, roller-cone drill bits, and many other applications. In an embodiment, a bearing assembly includes a support ring and a retention ring assembled with the support ring. The bearing assembly further includes a plurality of superhard bearing elements. The retention ring and at least a number of the superhard bearing element are collectively configured to restrict displacement of the at least a number of the superhard bearing elements. | 07-25-2013 |
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| 20120216793 | THIN FLAME BURNER FOR A FIREPLACE - A burner assembly for a fireplace, comprising a fuel-metering plate, a fuel-delivery plenum and a dividing plate. The fuel metering plate has tines that form a combed structure in an uppermost portion of the fuel-metering plate, the combed structure extending along a long dimension of the fuel-metering plate. The fuel-delivery plenum has a fuel chamber and the fuel-delivery plenum being coupled to the fuel-metering plate such that the fuel chamber extends along the long dimension of the fuel metering plate. The dividing plate is located between the fuel-metering plate and the fuel-delivery plenum. The dividing plate has a slotted opening that extends along the long dimension of the fuel metering plate, the slotted opening being in fluid communication with individual channels between the tines and with the fuel chamber. | 08-30-2012 |
| 20120216794 | MULTI-CHANNEL BURNER ASSEMBLY SIMULATANEOSULY ACCEPTING MULTIPLE DIFFERENT FUEL-AIR MIXTURES - A burner assembly comprising a burner casing having two or more separate chambers therein, the chambers being divided from each other by one or more walls. The assembly also comprises one or more input conduits each configured to deliver different fuel-air mixtures to at least one of the separated chambers. | 08-30-2012 |
| 20120216795 | FIREPLACE LINER - A fireplace liner comprising a first panel configured to be located in front of a fireplace burner assembly that has a lateral dimension that extends across a viewing window of a fireplace box. The first panel is configured to extend laterally along the lateral dimension, and, a rear end of the first panel, nearest to the burner assembly, includes a first trough having a vertical wall with a plurality of first slots therein. The linear comprises a second panel configured to be located behind the burner assembly in the box. The second panel is configured to extend laterally along the lateral dimension, and a front end of the second panel, nearest to the burner assembly, includes a second trough having another vertical wall with a plurality of second slots therein. The first and second slots permit secondary air flow there-through. | 08-30-2012 |
| 20120216797 | BAFFLE FOR A FIREPLACE - A heat deflection member having a first bend along a central axis of the heat deflection member that forms first and second opposing panels, and opposing first and second parallel edges of the heat deflection member having second and third bends formed parallel the central axis that form opposing first and second coupling flanges along at least a portion of a length of the opposing edges. A method of manufacturing a fireplace baffle and a pre-fabricated fireplace are also provided. | 08-30-2012 |
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| 20100011015 | SIMPLIFYING COMPLEX DATA STREAM PROBLEMS INVOLVING FEATURE EXTRACTION FROM NOISY DATA - Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source. | 01-14-2010 |
| 20100011192 | SIMPLIFYING COMPLEX DATA STREAM PROBLEMS INVOLVING FEATURE EXTRACTION FROM NOISY DATA - Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source. | 01-14-2010 |
| 20110131148 | SYSTEM, METHOD, AND APPARATUS FOR MANAGING PRICE INFORMATION WITH LOCKING MECHANISMS - A computer-implemented method for managing price information. Embodiments include receiving a mapping of interconnected components, identifying as a first subset components subject to a first fixed price agreement not subject to a second fixed price agreement that overlaps the first fixed price agreement, identifying as a second subset the components subject to the second fixed price agreement not subject to the first fixed price agreement, and identifying as a third subset the components subject to both the first fixed price agreement and the second fixed price agreement. The method also includes receiving a price change for a price associated with a component in one of the subsets of components, and distributing an offset of the price change to components in the other subsets of components. | 06-02-2011 |
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| 20120179601 | OFFSITE FINANCIAL ACCOUNT ONBOARDING - Offsite financial account onboarding is provided which creates a more streamlined process for a customer. The customer accesses a money services businesss business electronic system to request financial account setup. The onboarding system establishes account access to a pooled custodial account managed by the money services businesss business based on preliminary identification (ID) data from the customer. With only preliminary ID data, account access limits are assigned which reduces the risk of fraud or criminal activity with the customer's account access. Because account access is established with just the preliminary ID data, the customer may fully obtain account access directly from a mobile device. The money services businesss business provides additional graduated access levels depending on additional ID data provided by the customer. Thus, depending on the type of ID data provided by the customer, the customer's account access will have corresponding access level rights to the custodial account. | 07-12-2012 |
| 20130036054 | OFFSITE FINANCIAL ACCOUNT ONBOARDING - Offsite financial account onboarding is provided which creates a more streamlined process for a customer. The customer accesses a money services businesss business electronic system to request financial account setup. The onboarding system establishes account, access to a pooled custodial account managed by the money services businesss business based on preliminary identification (ID) data from the customer. With only preliminary ID data, account access limits are assigned which reduces the risk of fraud or criminal activity with the customer's account access. Because account access is established with just the preliminary ID data, the customer may fully obtain account access directly from a mobile device. The money services businesss business provides additional graduated access levels depending on additional ID data provided by the customer. Thus, depending on the type of ID data provided by the customer, the customer's account access will have corresponding access level rights to the custodial account. | 02-07-2013 |
| 20140258126 | OFFSITE FINANCIAL ACCOUNT ONBOARDING - Offsite financial account onboarding is provided which creates a more streamlined process for a customer. The customer accesses a money services business electronic system to request financial account setup. The onboarding system establishes account access to a pooled custodial account managed by the money services business based on preliminary identification (ID) data from the customer. With only preliminary ID data, account access limits are assigned which reduces the risk of fraud or criminal activity with the customer's account access. Because account access is established with just the preliminary ID data, the customer may fully obtain account access directly from a mobile device. The money services business provides additional graduated access levels depending on additional ID data provided by the customer. Thus, depending on the type of ID data provided by the customer, the customer's account access will have corresponding access level rights to the custodial account. | 09-11-2014 |
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| 20110301958 | System-Initiated Speech Interaction - Whenever an event occurs on a computing system which will accept a response from a user of the system, the system automatically determines whether or not to enable speech interaction with the system for the event response. Whenever speech interaction is enabled with the system for the event response, the system provides a notification to the user which informs the user of the event and their options for responding thereto, where these options include responding verbally. Whenever the user responds within a prescribed period of time via a voice command (VC), the system attempts to recognize the VC. Whenever the VC is successfully recognized, the system responds appropriately to the VC. | 12-08-2011 |
| 20120317210 | Asynchronous Video Threads - Described are systems and user interfaces for facilitating asynchronous communication with video threads. Implementations may enable members of a team to have threaded view of video messages, from which they can capture video, record their screen, and send, receive, and reply to a video message. The screen recording feature enables team members to share parts of their screen while simultaneously narrating, if desired. Video messages are threaded by topic and each conversation is visually represented. | 12-13-2012 |
| 20130139071 | PROXY FOR ASYNCHRONOUS MEETING PARTICIPATION - Embodiments described herein relate to enabling a lightweight way of recording and sharing video messages intended to provide input to a future meeting that cannot be personally attended. A person who cannot attend the meeting pre-records their thoughts and remarks for the meeting as video clips for presentation at the meeting. A physical device with at least a display is presented at the meeting. The physically present participants can play the pre-recorded clips on the device. Video of participants' responses to the clips is recorded and made available so that the represented attendee can view the participants' responses. | 05-30-2013 |
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| 20110250322 | Plastic Packaged Nutritional Liquids Comprising HMB - Disclosed are nutritional compositions comprising a plastic package and a nutritional liquid contained therein, wherein the nutritional liquid comprises beta-hydroxy-beta-methylbutyrate (HMB) and at least one of fat, protein, and carbohydrate. It has been found that HMB provides a buffering effect in the nutritional liquid to thus minimize an acidic pH shift that is more prevalent in plastic packages, and thus help maintain product stability over time. | 10-13-2011 |
| 20110256301 | Nutritional Emulsions Comprising Calcium HMB - Disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB, wherein the nutritional emulsion has a weight ratio of a soluble calcium binding capacity to soluble calcium of from about 2.3 to about 12.0. Also disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB, wherein the nutritional emulsion comprises less than 900 mg/L of soluble calcium in a weight ratio of calcium HMB to soluble calcium of from 6:1 to 15:1. The nutritional emulsions are surprisingly stable and generate minimal or no bitter flavors or after taste over time. | 10-20-2011 |
| 20140030420 | NUTRITIONAL POWDERS COMPRISING SPRAY DRIED HMB - Spray dried nutritional powders include soluble calcium, protein, and at least one of a soluble citrate, a soluble phosphate, and combinations thereof as at least one chelating agent. At least a portion of the soluble calcium is calcium HMB. At least a portion of the protein is soluble protein. The spray dried nutritional powders have a weight ratio of soluble calcium binding capacity to total soluble calcium of from about 2.3:1 to about 12:1. The calcium HMB, the at least one chelating agent, and the protein are spray dried together. | 01-30-2014 |
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| 20090248502 | COMPUTING A TIME-DEPENDENT VARIABILITY VALUE - A system that facilitates computation of a time-dependent variability value is described herein. The system includes a receiver component that receives a plurality of items, wherein each item has a timestamp corresponding thereto. The system further includes a value generator component that outputs a time-dependent variability value for an item in the plurality of items, wherein the time-dependent variability value is indicative of a recent frequency of use of the item in comparison to a frequency of use of the item over a defined period of time. | 10-01-2009 |
| 20090254847 | ANALYSIS OF VISUALLY-PRESENTED DATA - A person may interact with visually-presented data in order to specify an analysis to be performed on the data. Data may be presented through a browser or other program in a visual form, such as a chart or graph. The person may interact with the visual presentation of the data in order to choose a specific body of data or a portion thereof. An analysis may be performed on the chosen data. The analysis to be performed may be selected based on features of the data and/or based on the person's indication of which analysis is to be performed. A decision tree may be used to choose the particular analysis to be performed. | 10-08-2009 |
| 20130232552 | Automatic Context Sharing with Privacy - The subject disclosure is directed towards a technology by which a computing device user may share context-related information (e.g., including current activity) with other recipient machines. A requestor may request to peek at a user's context, and if the requestor is valid (pre-approved by the user), a response based on context-related information is sent, which may be via a cloud service. The response may be filtered and/or adjusted based upon the identity of the requestor and other information associated with that identity, e.g., filtering criteria set by the user. Also described is notifying the user of the peek request, and logging information corresponding to the request and response. A broadcast message may also be sent by the device to share context without waiting for a peek request. | 09-05-2013 |
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| 20080274230 | Iron-Containing Human Milk Fortifier With Improved Antimicrobial Properties - Disclosed are human milk fortifier compositions, in either powder or liquid forms, comprising nutrients and selected iron-containing materials, wherein the fortifiers when added to human milk do not significantly inhibit or otherwise eliminate the inherent, in-vitro antimicrobial properties of the milk. This is accomplished by formulating the compositions with iron-containing insoluble iron, soluble bound iron, or combinations thereof, with little or no soluble unbound iron. Also disclosed are methods of providing nutrition to infants, especially preterm infants, by adding the human milk fortifier described herein with human milk to form a fortified human milk, and then administering the fortified human milk to the infant. The fortifier can also be used to fortify other infant formulas. | 11-06-2008 |
| 20090162518 | Stable Nutritional Powder - Disclosed are compositions comprising carbohydrate; lipid, comprising from about 0.25% to about 2.5 % lecithin by weight of total lipid; from about 90% to about 99.5% of intact protein by weight of total protein; and from about 0.5% to about 10% of at least one hydrolyzed protein selected from the group consisting of hydrolyzed casein protein and hydrolyzed whey protein; wherein the hydrolyzed protein has a degree of hydrolysis of between about 23% and about 90%, and wherein the compositions are nutritional powders. The nutritional powders provide improved oxidative stability and sensory performance. | 06-25-2009 |
| 20090162521 | Stable Nutritional Powder - Disclosed are compositions comprising carbohydrate; lipid, comprising from about 0.25% to about 2.5% lecithin by weight of total lipid; from about 0.5% to about 10% hydrolyzed casein protein by weight of total protein; and from about 90% to about 99.5% intact protein by weight of total protein; wherein the compositions are nutritional powders. The nutritional powders provide improved oxidative stability and sensory performance. | 06-25-2009 |
| 20100247734 | Methods for Making Nutritional Compositions Comprising Curcuminoids - Disclosed are nutritional compositions and methods for preparing the compositions, comprising fat, protein, and carbohydrate, including a combination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, which combination is solubilized in a polar oil having an HLB value of from about 0.7 to about 14 wherein the weight ratio of the bisdemethoxycurcumin to the curcumin is from about 1:1 to about 1:7 and the weight ratio of the bisdemethoxycurcumin to the demethoxycurcumin is from about 1:1 to about 1:2.5. The composition provides a selected ratio of curcuminoids having improved biological activity, bioavailability, and reduced color impact. | 09-30-2010 |
| 20100249031 | Nutritional Composition Comprising Curcuminoids and Methods of Manufacture - Disclosed are nutritional compositions and methods for preparing the compositions, comprising fat, protein, and carbohydrate, including a combination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, which combination is solubilized in a polar oil having an HLB value of from about 0.7 to about 14 wherein the weight ratio of the bisdemethoxycurcumin to the curcumin is from about 1:1 to about 1:7 and the weight ratio of the bisdemethoxycurcumin to the demethoxycurcumin is from about 1:1 to about 1:2.5. The composition provides a selected ratio of curcuminoids having improved biological activity, bioavailability, and reduced color impact. | 09-30-2010 |
| 20110250340 | SHELF STABLE NUTRITIONAL LIQUIDS COMPRISING BETA ALANINE - Disclosed are shelf-stable nutritional liquids comprising beta alanine, protein, and a carbohydrate system, wherein the shelf-stable nutritional liquid includes a molar ratio of the DE of the carbohydrate system to the lysine amino nitrogen of the protein of less than about 1.0 and or a molar ratio of the DE of the carbohydrate system to the beta alanine of less than about 3.0. The nutritional liquids are surprisingly stable over extended periods of time and exhibit minimal reduction in the concentration of beta alanine over shelf life. | 10-13-2011 |
| 20110256272 | Aseptically Packaged Nutritional Liquids Comprising HMB - Disclosed are nutritional compositions comprising a peroxide-treated aseptic package and a nutritional liquid contained therein, wherein the nutritional liquid comprises beta-hydroxy-beta-methylbutyrate (HMB) and at least one of fat, carbohydrate, and protein. The HMB provides a buffering effect in the nutritional liquid to thus minimize an acidic pH shift that is prevalent in aseptically sterilized packages, and thus helps maintain product stability over time. | 10-20-2011 |
| 20110256297 | Nutritional Emulsions Comprising Calcium HMB and Soluble Protein - Disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB wherein soluble protein comprises from about 50% to 100% by weight of the total protein. Also disclosed are nutritional emulsions comprising fat, carbohydrate, protein, and calcium HMB wherein soluble protein comprises from about 50% to 100% by weight of the protein and the emulsion has a weight ratio of soluble protein to calcium HMB of from about 5:1 to about 12:1. The nutritional emulsions are surprisingly stable and generate minimal or no bitter flavors or after taste over time. | 10-20-2011 |
| 20110305799 | SUBSTANTIALLY CLEAR NUTRITIONAL LIQUIDS COMPRISING CALCIUM HMB AND SOLUBLE PROTEIN - Disclosed are substantially clear nutritional liquids comprising protein and calcium HMB wherein soluble protein represents from about 65% to 100% by weight of total protein. The liquids have a pH of from about 2.8 to about 4.6 and may be manufactured as a hot fill product. The substantially clear nutritional liquids may also have a weight ratio of calcium HMB to soluble calcium of from 4.5:1 to 7.3:1. In some embodiments, the substantially clear nutritional liquids are substantially free of fat, and may optionally include isomaltulose and/or beta alanine. | 12-15-2011 |
| 20140037797 | NUTRITIONAL PRODUCTS COMPRISING BETA-HYDROXY-BETA-METHYLBUTYRATE - Disclosed are shelf stable nutritional products including beta-hydroxy-beta-methylbutyrate (HMB) and an oxidatively active species such as iron or copper. The HMB restricts the capacity of the oxidative species to catalyze the oxidation of nutrients such as fatty acids and vitamins thereby imparting both nutritional benefits and sensory benefits to the nutritional products. | 02-06-2014 |
| 20140037798 | LIQUID NUTRITIONAL PRODUCTS COMPRISING METAL AMINO ACID CHELATES - Disclosed are shelf stable nutritional liquids including metal amino acid chelates. Metal amino acid chelates, such as copper amino acid chelates and iron amino acid chelates, limit the capacity of incompletely bound copper and iron to catalyze the oxidation of sensitive nutrients such as vitamins, particularly vitamin A, vitamin B12 and vitamin C, thereby imparting both nutritional benefits and sensory benefits to the nutritional liquids. | 02-06-2014 |
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| 20100112042 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics - Processes and compositions for liposomal delivery of therapeuticals prepared by contacting an aqueous solution of an active agent with a solution of liposome-forming components containing one or more DILA2 amino acid compounds or lipids in organic solvent to form an impinging stream. A protocol including flow rates, pH, and an incubation period are used to control formation of liposomal components for therapeutic applications. The impinging stream may be collected and incubated to prepare a liposomal formulation which encapsulates the active agent. The composition can be quenched with buffer and filtered by tangential flow and diafiltration and other means for finishing as a pharmaceutical composition. An efficiency for delivering a drug cargo is provided. Compositions can include a liposome containing one or more carrier particles, each carrier particle having an active agent and a peptide, wherein the ratio of the mass of the peptide plus the mass of the liposome to the mass of the active agent is less than about 15. | 05-06-2010 |
| 20100240731 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS - Lipopeptide compounds comprising a peptide having 2 to 100 amino acid residues, and having a lipophilic group attached to at least one terminus of the peptide or to at least one amino acid residue of the peptide, and salts and uses thereof. The lipophilic group may be attached to the N-terminus, C-terminus or both termini of the peptide. The lipophilic group may be attached to at least one interal amino acid residue (i.e., an amino acid residue that is not the N-terminus or the C-terminus amino acid residue of the peptide). The lipophilic group may be attached to either termini or both and at least one internal amino acid residue. | 09-23-2010 |
| 20120277289 | ACTIVITY GENERATING DELIVERY MOLECULES - Activity-generating delivery molecules comprising the structure R | 11-01-2012 |
| 20130039970 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics - Processes and compositions for liposomal delivery of therapeuticals prepared by contacting an aqueous solution of an active agent with a solution of liposome-forming components containing one or more DILA2 amino acid compounds or lipids in organic solvent to form an impinging stream. A protocol including flow rates, pH, and an incubation period are used to control formation of liposomal components for therapeutic applications. The impinging stream may be collected and incubated to prepare a liposomal formulation which encapsulates the active agent. The composition can be quenched with buffer and filtered by tangential flow and diafiltration and other means for finishing as a pharmaceutical composition. | 02-14-2013 |
| 20130231382 | LIPOPEPTIDES FOR DELIVERY OF NUCLEIC ACIDS - Lipopeptide compounds comprising a peptide having 2 to 100 amino acid residues, and having a lipophilic group attached to at least one terminus of the peptide or to at least one amino acid residue of the peptide, and salts and uses thereof. The lipophilic group may be attached to the N-terminus, C-terminus or both termini of the peptide. The lipophilic group may be attached to at least one interal amino acid residue (i.e., an amino acid residue that is not the N-terminus or the C-terminus amino acid residue of the peptide). The lipophilic group may be attached to either termini or both and at least one internal amino acid residue. | 09-05-2013 |
| 20150073038 | DELIVERY MOLECULES FOR THERAPEUTICS - Activity-generating delivery molecules comprising the structure R | 03-12-2015 |
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| 20090300472 | METHOD OF AUTHORING, DEPLOYING AND USING INTERACTIVE, DATA-DRIVEN TWO OR MORE DIMENSIONAL CONTENT - A method whereby dynamic, interactive, two or more dimensional media can be assembled and delivered where the need for pre-packaged binary content files and pre-compiled content is eliminated by using a markup language, a standard URI to identify local and/or remote media resources within a markup text, a standard protocol to retrieve the resource, a parser to load resources from the native format and a markup language to define behavior and where dynamic, interactive, n-dimensional media is achieved by using a markup language, connecting or embedding content into a local or remote data source, dragging-and-dropping markup text into a content provider application, updating content using a form, establishing a two-way connection between content and one or more data sources such that changing to the data source(s) and seeing the results propagate to the scene changing the content and seeing the results propagate to the data source(s) and using a markup language to issue commands, configure interaction, and create behavior. | 12-03-2009 |
| 20100206042 | Emissions Monitoring Apparatus, System, and Method - Some embodiments of the invention generally relate to an apparatus configured to monitor emissions. The apparatus includes a sampling chamber, a gas analyzer, and a particulate matter analyzer. The sampling chamber is configured to receive a portion of an exhaust flow from an exhaust stack. The portion of the exhaust flow comprises one or more gases and particulate matter. The gas analyzer is configured to receive the portion of the exhaust flow to measure at least one emission level of the one or more gases using a laser and output a signal indicative thereof. The particulate matter analyzer is operatively connected to the sampling chamber and is configured to measure the particulate matter using optics and output a signal indicative thereof. | 08-19-2010 |
| 20140201610 | AUTHORING, DEPLOYING AND USING INTERACTIVE, DATA-DRIVEN TWO OR MORE DIMENSIONAL CONTENT - A method whereby dynamic, interactive, two or more dimensional media can be assembled and delivered where the need for pre-packaged binary content files and pre-compiled content is eliminated by using a markup language, a standard URI to identify local and/or remote media resources within a markup text, a standard protocol to retrieve the resource, a parser to load resources from the native format and a markup language to define behavior and where dynamic, interactive, n-dimensional media is achieved by using a markup language, connecting or embedding content into a local or remote data source, dragging-and-dropping markup text into a content provider application, updating content using a form, establishing a two-way connection between content and one or more data sources such that changing to the data source(s) and seeing the results propagate to the scene changing the content and seeing the results propagate to the data source(s) and using a markup language to issue commands, configure interaction, and create behavior. | 07-17-2014 |
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| 20110008349 | Hypoxia Induced Mitogenic Factor - We found that FIZZ1/RELMα is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELMα was located in the pulmonary vasculature, bronchial epithelial cells, and type II pneumocytes. Recombinant FIZZ1/RELMα protein stimulates rat pulmonary microvascular smooth muscle cell (RPSM) proliferation dose-dependently. Therefore, we renamed this gene as hypoxia-induced mitogenic factor (HIMF). HIMF strongly activated Akt phosphorylation. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 inhibits HIMF-activated Akt phosphorylation. It also inhibits HIMF-stimulated RPSM proliferation. Thus, the PI3K/Akt pathway, at least in part, mediates the proliferative effect of HIMF. HIMF also has angiogenic and vasoconstrictive activity. Notably, HIMF increases pulmonary arterial pressure and vascular resistance more potently than either endothelin-1 or angiotensin II. | 01-13-2011 |
| 20120039839 | Hypoxia Induced Mitogenic Factor - We found that FIZZ1/RELMα is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELMα was located in the pulmonary vasculature, bronchial epithelial cells, and type II pneumocytes. Recombinant FIZZ1/RELMα protein stimulates rat pulmonary microvascular smooth muscle cell (RPSM) proliferation dose-dependently. Therefore, we renamed this gene as hypoxia-induced mitogenic factor (HIMF). HIMF strongly activated Akt phosphorylation. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 inhibits HIMF-activated Akt phosphorylation. It also inhibits HIMF-stimulated RPSM proliferation. Thus, the PI3K/Akt pathway, at least in part, mediates the proliferative effect of HIMF. HIMF also has angiogenic and vasoconstrictive activity. Notably, HIMF increases pulmonary arterial pressure and vascular resistance more potently than either endothelin-1 or angiotensin II. | 02-16-2012 |
| 20120141489 | Hypoxia Induced Mitogenic Factor - We found that FIZZ1/RELMα is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELMα was located in the pulmonary vasculature, bronchial epithelial cells, and type II pneumocytes. Recombinant FIZZ1/RELMα protein stimulates rat pulmonary microvascular smooth muscle cell (RPSM) proliferation dose-dependently. Therefore, we renamed this gene as hypoxia-induced mitogenic factor (HIMF). HIMF strongly activated Akt phosphorylation. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 inhibits HIMF-activated Akt phosphorylation. It also inhibits HIMF-stimulated RPSM proliferation. Thus, the PI3K/Akt pathway, at least in part, mediates the proliferative effect of HIMF. HIMF also has angiogenic and vasoconstrictive activity. Notably, HIMF increases pulmonary arterial pressure and vascular resistance more potently than either endothelin-1 or angiotensin II. | 06-07-2012 |
| 20130243782 | HYPOXIA-INDUCED MITOGENIC FACTOR - We found that FIZZ1/RELMα is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELMα was located in the pulmonary vasculature, bronchial epithelial cells, and type II pneumocytes. Recombinant FIZZ1/RELMα protein stimulates rat pulmonary microvascular smooth muscle cell (RPSM) proliferation dose-dependently. Therefore, we renamed this gene as hypoxia-induced mitogenic factor (HIMF). HIMF strongly activated Akt phosphorylation. The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 inhibits HIMF-activated Akt phosphorylation. It also inhibits HIMF-stimulated RPSM proliferation. Thus, the PI3K/Akt pathway, at least in part, mediates the proliferative effect of HIMF. HIMF also has angiogenic and vasoconstrictive activity. Notably, HIMF increases pulmonary arterial pressure and vascular resistance more potently than either endothelin-I or angiotensin II. | 09-19-2013 |
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| 20100028355 | HIMF AND BTK IN PULMONARY, CARDIAC AND INFLAMMATION DISORDERS - Hypoxia induced mitogenic factor (HIMF) is a member of the “found in inflammatory zone” (FIZZ)/resistin family of proteins and has potent mitogenic, angiogenic, and vasoconstrictive effects in the lung vasculature. The receptor/binding partners for this family of proteins have been largely unknown. We identified Bruton's tyrosine kinase (BTK) as a functional HIMF binding partner through GST-HIMF pull-downs and mass spectrometry. Using primary cultured HIMF-stimulated murine bone marrow cells, we demonstrated that BTK was recruited to the leading edge of the cells. We also demonstrated that BTK and the closely related tyrosine kinase Fyn, colocalized at the growth cone process in these cells. HIMF stimulation induced BTK autophosphorylation, which peaked at 2.5 minutes. A transwell migration assay showed that treatment with recombinant murine HIMF induced migration of primary cultured bone marrow cells, which was completely blocked by the BTK inhibitor, LFM-A13. In vivo studies, using the rat hindlimb ischemia model, revealed that HIMF can stimulate angiogenesis in the hypoxic tissue probably through inducing the migration of endothelial progenitor cells (EPCs) to areas of active angiogenesis. Our results indicate that HIMF may acts as a chemotactic molecule in stimulating the migration of leukocytes/EPCs from bone marrow to targeted tissues through activation of the BTK pathway. | 02-04-2010 |
| 20100204100 | BIOLOGICAL AGENTS ACTIVE IN CENTRAL NERVOUS SYSTEM - Cell-permeant fusion peptides Tat-PDZ can dose-dependently reduce the threshold for anesthesia. PDZ domain-mediated protein interactions at synapses in the central nervous system play an important role in the molecular mechanisms of anesthesia. Moreover, Tat-PDZ cell-permeant fusion peptides are delivered intracellularly into neurons in the central nervous system subsequent to intraperitoneally injection. By in vitro and in vivo binding assays, we found that the Tat-PDZ dose-dependently inhibited the interactions between NMDARs and PSD-95. Furthermore, behavior testing showed that animals given Tat-PDZ exhibited significantly reduced established inflammatory pain behaviors compared to vehicle-treated group. Our results indicate that by disrupting NMDAR/PSD-95 protein interactions, the Tat-PDZ cell-permeable fusion peptides provide a new approach for inflammatory pain therapy. | 08-12-2010 |
| 20110178160 | Inhibition of Interaction of PSD93 and PSDS95 with nNOS and NMDA Receptors - PSD-95/SAP90 antisense-treated animals not only experience a significant decrease in MAC for isoflurane, but also experience an attenuation in the NMDA-induced increase in isoflurane MAC. PSD-95/SAP90 appears to mediate the role of the NMDA receptor in determining the MAC of inhalational anesthetics. Suppression of the expression of PSD-95/SAP90 in the spinal cord significantly attenuates responses to painful stimuli mediated through the N-methyl-D-aspartate receptor activation. In spinal cord neurons PSD-95/SAP90 interacts with the N-methyl-D-aspartate receptor subunits 2A/2B. Activation of the N-methyl-D-aspartate receptor in spinal hyperalgesia results in association of the N-methyl-D-aspartate receptor with PSD-95/SAP90. PSD-95/SAP90 is required for hyperalgesia triggered via the N-methyl-D-aspartate receptor at the spinal cord level. | 07-21-2011 |
| 20120329723 | Biological Agents Active in Central Nervous System - Cell-permeant fusion peptides Tat-PDZ can dose-dependently reduce the threshold for anesthesia. PDZ domain-mediated protein interactions at synapses in the central nervous system play an important role in the molecular mechanisms of anesthesia. Moreover, Tat-PDZ cell-permeant fusion peptides are delivered intracellularly into neurons in the central nervous system subsequent to intraperitoneally injection. By in vitro and in vivo binding assays, we found that the Tat-PDZ dose-dependently inhibited the interactions between NMDARs and PSD-95. Furthermore, behavior testing showed that animals given Tat-PDZ exhibited significantly reduced established inflammatory pain behaviors compared to vehicle-treated group. Our results indicate that by disrupting NMDAR/PSD-95 protein interactions, the Tat-PDZ cell-permeable fusion peptides provide a new approach for inflammatory pain therapy. | 12-27-2012 |
| 20140080151 | ANTI-HIMF ANTIBODIES TO TREAT LUNG DISEASES - Hypoxia induced mitogenic factor (HIMF) is a member of the “found in inflammatory zone” (FIZZ)/resistin family of proteins and has potent mitogenic, angiogenic, and vasoconstrictive effects in the lung vasculature. The receptor/binding partners for this family of proteins have been largely unknown. We identified Bruton's tyrosine kinase (BTK) as a functional HIMF binding partner through GST-HIMF pull-downs and mass spectrometry. Using primary cultured HIMF-stimulated murine bone marrow cells, we demonstrated that BTK was recruited to the leading edge of the cells. A transwell migration assay showed that treatment with recombinant murine HIMF induced migration of primary cultured bone marrow cells, which was completely blocked by a BTK inhibitor. In vivo studies revealed that HIMF can stimulate angiogenesis in the hypoxic tissue. Our results indicate that HIMF may act as a chemotactic molecule in stimulating the migration of leukocytes/EPCs from bone marrow to targeted tissues through activation of the BTK pathway. | 03-20-2014 |
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| 20090156006 | COMPOSITIONS AND METHODS FOR CMP OF SEMICONDUCTOR MATERIALS - The present invention provides a chemical-mechanical polishing (CMP) composition suitable for polishing semi-conductor materials. The composition comprises an abrasive, an organic amino compound, an acidic metal complexing agent and an aqueous carrier A CMP method for polishing a surface of a semiconductor material utilizing the composition is also disclosed. | 06-18-2009 |
| 20100144149 | METHOD TO SELECTIVELY POLISH SILICON CARBIDE FILMS - The present invention provides a method for selectively removing silicon carbide from the surface of a substrate in preference to silicon dioxide. The method comprises abrading a surface of substrate with a polishing composition that comprises a particulate abrasive, at least one acidic buffering agent, and an aqueous carrier. | 06-10-2010 |
| 20110136344 | COMPOSITION AND METHOD FOR POLISHING POLYSILICON - The invention provides a polishing composition comprising silica, an aminophosphonic acid, a polysaccharide, a tetraalkylammonium salt, a bicarbonate salt, an azole ring, and water, wherein the polishing composition has a pH of about 7 to about 11. The invention further provides a method of polishing a substrate with the polishing composition. | 06-09-2011 |
| 20140191155 | COMPOSITION AND METHOD FOR POLISHING POLYSILICON - The invention provides a polishing composition comprising silica, an aminophosphonic acid, a polysaccharide, a tetraalkylammonium salt, a bicarbonate salt, an azole ring, and water, wherein the polishing composition has a pH of about 7 to about 11. The invention further provides a method of polishing a substrate with the polishing composition. | 07-10-2014 |
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| 20100171978 | DELIVERY EXPERT SYSTEM AND METHOD - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 07-08-2010 |
| 20110216366 | Delivery Expert System, Method and Computer Program Product - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 09-08-2011 |
| 20110249288 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - Embodiments disclosed herein can facilitate delivery of a document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon input conditions which may include a time-variable set of input conditions such as identifying non-business days and/or hours at the destination. The document can be a fax, an email, or a voice mail. The actions may include resubmitting the document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, identifying the destination as a technical problem, or a combination thereof. | 10-13-2011 |
| 20120162695 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - Embodiments disclosed herein can facilitate delivery of a document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon input conditions which may include a time-variable set of input conditions such as identifying non-business days and/or hours at the destination. The document can be a fax, an email, or a voice mail. The actions may include resubmitting the document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, identifying the destination as a technical problem, or a combination thereof. | 06-28-2012 |
| 20120188607 | Delivery Expert System, Method and Computer Program Product - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Actions to be taken are based upon a time-variable set of input conditions which may be determined from one or more of the destination, the source, a database of past delivery attempts, and a human analyst. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, sending a request to the source or destination for additional delivery information, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 07-26-2012 |
| 20130301075 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Rules may be stored in a database. The database may include rules based on past delivery information or new delivery instructions. When an input condition is determined, the database may be traversed to determine an action based on the set of rules. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 11-14-2013 |
| 20140307284 | DELIVERY EXPERT SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - An automated rule-based system for facilitating delivery of a fax document from a source to a destination over a network where an initial delivery attempt has been unsuccessful. Rules may be stored in a database. The database may include rules based on past delivery information or new delivery instructions. When an input condition is determined, the database may be traversed to determine an action based on the set of rules. The actions may include one or more of resubmitting the fax document to the network for a next delivery attempt, cancelling the document, and identifying the destination as a technical problem. The input conditions may include an identification of non-business days and non-business hours. | 10-16-2014 |
